Diras2 (DIRAS family GTPase 2) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Gene: Diras2 (DIRAS family GTPase 2) Heterocephalus glaber
Analyze
Symbol: Diras2
Name: DIRAS family GTPase 2
RGD ID: 18927303
Description: ENCODES a protein that exhibits GDP binding (inferred); GTP binding (inferred); GTPase activity (inferred); INVOLVED IN signal transduction (inferred); FOUND IN membrane (inferred); plasma membrane (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: GTP-binding protein Di-Ras2
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248681,832,727 - 1,863,089 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248681,832,696 - 1,862,947 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:21993625   PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Diras2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248681,832,727 - 1,863,089 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248681,832,696 - 1,862,947 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
DIRAS2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38990,609,832 - 90,642,824 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl990,609,832 - 90,642,862 (-)EnsemblGRCh38hg38GRCh38
GRCh37993,372,114 - 93,405,106 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36992,411,934 - 92,444,928 (-)NCBINCBI36Build 36hg18NCBI36
Build 34990,451,667 - 90,484,662NCBI
Celera963,806,753 - 63,839,749 (-)NCBICelera
Cytogenetic Map9q22.2NCBI
HuRef963,052,764 - 63,085,766 (-)NCBIHuRef
CHM1_1993,518,607 - 93,551,600 (-)NCBICHM1_1
T2T-CHM13v2.09102,774,878 - 102,807,866 (-)NCBIT2T-CHM13v2.0
Diras2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391352,658,411 - 52,685,390 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1352,658,416 - 52,685,315 (-)EnsemblGRCm39 Ensembl
GRCm381352,504,375 - 52,531,354 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1352,504,380 - 52,531,279 (-)EnsemblGRCm38mm10GRCm38
MGSCv371352,599,744 - 52,626,205 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361352,516,812 - 52,543,086 (-)NCBIMGSCv36mm8
Celera1353,580,860 - 53,607,323 (-)NCBICelera
Cytogenetic Map13A5NCBI
cM Map1327.3NCBI
Diras2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81712,882,224 - 12,913,366 (+)NCBIGRCr8
mRatBN7.21712,730,040 - 12,761,511 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1712,725,149 - 12,761,663 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1712,691,363 - 12,692,565 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01714,296,434 - 14,297,634 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01712,613,401 - 12,614,601 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01712,738,078 - 12,766,700 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1712,762,752 - 12,763,952 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01714,826,986 - 14,858,039 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41718,604,023 - 18,605,223 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11718,604,054 - 18,604,654 (+)NCBI
Celera1712,518,650 - 12,519,850 (+)NCBICelera
Cytogenetic Map17p14NCBI
Diras2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555151,526,333 - 1,551,811 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049555151,526,436 - 1,551,811 (+)NCBIChiLan1.0ChiLan1.0
DIRAS2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21148,823,151 - 48,856,390 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1948,825,551 - 48,858,780 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0961,694,582 - 61,727,808 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1989,794,504 - 89,827,725 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl989,797,897 - 89,798,496 (-)Ensemblpanpan1.1panPan2
DIRAS2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1196,057,595 - 96,082,063 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha196,510,091 - 96,535,201 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0196,660,495 - 96,685,610 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl196,660,789 - 96,685,608 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1196,287,919 - 96,312,999 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0196,008,459 - 96,033,556 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0196,768,562 - 96,793,678 (+)NCBIUU_Cfam_GSD_1.0
Diras2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494412,232,904 - 12,264,012 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049367801,380,876 - 1,381,475 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049367801,377,569 - 1,408,889 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
DIRAS2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl141,964,849 - 1,987,891 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1141,964,842 - 1,987,900 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2142,406,324 - 2,406,923 (+)NCBISscrofa10.2Sscrofa10.2susScr3
DIRAS2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.112101,071,595 - 101,102,883 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl12101,074,992 - 101,075,591 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603889,405,540 - 89,437,227 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSHGLT00000011096   ⟹   ENSHGLP00000010973
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046248681,832,727 - 1,863,089 (+)Ensembl
RefSeq Acc Id: XM_004870057   ⟹   XP_004870114
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248681,832,696 - 1,862,947 (+)NCBI
Protein Sequences
Protein RefSeqs XP_004870114 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EHB15736 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000010973
  ENSHGLP00100002725
  ENSHGLP00100032261
  ENSHGLP00100060853
GenBank Protein JAN97874 (Get FASTA)   NCBI Sequence Viewer  
Reference Protein Sequences
RefSeq Acc Id: XP_004870114   ⟸   XM_004870057
- UniProtKB: G5C2H5 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSHGLP00000010973   ⟸   ENSHGLT00000011096


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000007875 Ensembl, ENTREZGENE
  ENSHGLG00100002122 UniProtKB/TrEMBL
Ensembl Transcript ENSHGLT00000011096 ENTREZGENE
  ENSHGLT00100002780 UniProtKB/TrEMBL
  ENSHGLT00100047990 UniProtKB/TrEMBL
  ENSHGLT00100068894 UniProtKB/TrEMBL
Gene3D-CATH 3.40.50.300 UniProtKB/TrEMBL
InterPro P-loop_NTPase UniProtKB/TrEMBL
  Small_GTP-bd_dom UniProtKB/TrEMBL
  Small_GTPase UniProtKB/TrEMBL
  Small_GTPase_Ras-type UniProtKB/TrEMBL
KEGG Report hgl:101720081 UniProtKB/TrEMBL
NCBI Gene Diras2 ENTREZGENE
PANTHER GTP-BINDING PROTEIN DI-RAS2 UniProtKB/TrEMBL
  PTHR24070 UniProtKB/TrEMBL
Pfam Ras UniProtKB/TrEMBL
PRINTS RASTRNSFRMNG UniProtKB/TrEMBL
PROSITE RAB UniProtKB/TrEMBL
  RAS UniProtKB/TrEMBL
  RHO UniProtKB/TrEMBL
SMART RAB UniProtKB/TrEMBL
  RAS UniProtKB/TrEMBL
  RHO UniProtKB/TrEMBL
Superfamily-SCOP SSF52540 UniProtKB/TrEMBL
UniProt G5C2H5 ENTREZGENE, UniProtKB/TrEMBL