Hic2 (HIC ZBTB transcriptional repressor 2) - Rat Genome Database

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Gene: Hic2 (HIC ZBTB transcriptional repressor 2) Rattus norvegicus
Analyze
Symbol: Hic2
Name: HIC ZBTB transcriptional repressor 2
RGD ID: 1305338
Description: Predicted to enable DNA-binding transcription repressor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in negative regulation of transcription by RNA polymerase II; regulation of cytokine production; and regulation of immune system process. Predicted to be located in nucleus. Predicted to be active in nucleoplasm. Orthologous to human HIC2 (HIC ZBTB transcriptional repressor 2); INTERACTS WITH 17beta-estradiol; 6-propyl-2-thiouracil; acrylamide.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: hypermethylated in cancer 2; LOC287940
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81197,241,308 - 97,294,429 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1197,240,704 - 97,271,713 (-)EnsemblGRCr8
mRatBN7.21183,737,075 - 83,789,554 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1183,738,874 - 83,767,484 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1192,468,892 - 92,497,416 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01185,130,042 - 85,158,569 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01184,183,649 - 84,212,175 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01187,988,213 - 88,016,825 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1187,988,213 - 88,016,825 (-)Ensemblrn6Rnor6.0
Rnor_5.01191,040,376 - 91,092,856 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41185,740,737 - 85,770,511 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1182,501,044 - 82,529,506 (-)NCBICelera
RGSC_v3.11185,783,605 - 85,788,018 (-)NCBI
Cytogenetic Map11q23NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View
megacolon  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
nucleoplasm  (IBA,ISO)
nucleus  (IEA,ISO)

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
4. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
6. Comprehensive gene review and curation RGD comprehensive gene curation
Additional References at PubMed
PMID:11554746   PMID:12052894  


Genomics

Comparative Map Data
Hic2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81197,241,308 - 97,294,429 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1197,240,704 - 97,271,713 (-)EnsemblGRCr8
mRatBN7.21183,737,075 - 83,789,554 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1183,738,874 - 83,767,484 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1192,468,892 - 92,497,416 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01185,130,042 - 85,158,569 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01184,183,649 - 84,212,175 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01187,988,213 - 88,016,825 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1187,988,213 - 88,016,825 (-)Ensemblrn6Rnor6.0
Rnor_5.01191,040,376 - 91,092,856 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41185,740,737 - 85,770,511 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1182,501,044 - 82,529,506 (-)NCBICelera
RGSC_v3.11185,783,605 - 85,788,018 (-)NCBI
Cytogenetic Map11q23NCBI
HIC2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382221,417,371 - 21,451,463 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2221,416,504 - 21,451,463 (+)Ensemblhg38GRCh38
GRCh372221,771,660 - 21,805,752 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362220,101,693 - 20,135,752 (+)NCBIBuild 36Build 36hg18NCBI36
Build 342220,096,246 - 20,130,302NCBI
Celera225,515,817 - 5,524,520 (-)NCBICelera
Cytogenetic Map22q11.21NCBI
HuRef224,831,266 - 4,839,973 (+)NCBIHuRef
CHM1_12221,772,928 - 21,805,973 (+)NCBICHM1_1
T2T-CHM13v2.02221,896,880 - 21,930,996 (-)NCBIT2T-CHM13v2.0
Hic2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391617,051,451 - 17,081,294 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1617,051,436 - 17,081,294 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm381617,233,587 - 17,263,430 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1617,233,572 - 17,263,430 (+)Ensemblmm10GRCm38
MGSCv371617,233,680 - 17,263,523 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361617,147,150 - 17,176,993 (+)NCBIMGSCv36mm8
Celera1617,806,402 - 17,836,239 (+)NCBICelera
Cytogenetic Map16A3NCBI
cM Map1610.68NCBI
Hic2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495544217,626,190 - 17,643,455 (+)Ensembl
ChiLan1.0NW_00495544217,610,042 - 17,643,381 (+)NCBIChiLan1.0ChiLan1.0
HIC2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22331,035,190 - 31,070,717 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12233,584,202 - 33,619,723 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0223,603,972 - 3,639,341 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1377,445,100 - 77,453,976 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl377,445,100 - 77,454,473 (-)EnsemblpanPan2panpan1.1
HIC2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12630,771,555 - 30,804,652 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2630,776,464 - 30,780,173 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha2630,729,504 - 30,762,597 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.02632,176,739 - 32,209,855 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2632,181,651 - 32,185,360 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12630,226,722 - 30,259,812 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02629,850,536 - 29,883,623 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02630,940,328 - 30,973,651 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Hic2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118140,525,714 - 140,551,694 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366192,205,464 - 2,214,146 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049366192,205,106 - 2,214,199 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
HIC2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1450,365,851 - 50,368,634 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.11450,347,575 - 50,373,007 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21453,799,713 - 53,821,429 (+)NCBISscrofa10.2Sscrofa10.2susScr3
HIC2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1194,584,633 - 4,622,519 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl194,613,833 - 4,617,835 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_0236660852,378,628 - 2,413,506 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Hic2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247471,067,927 - 1,092,757 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046247471,065,864 - 1,096,164 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Hic2
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v142,506,185 - 2,532,362 (+)NCBIRrattus_CSIRO_v1

miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:1147
Count of miRNA genes:349
Interacting mature miRNAs:471
Transcripts:ENSRNOT00000002545
Prediction methods:Microtar, Miranda, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
10058954Gmadr7Adrenal mass QTL 72.490.0049adrenal gland mass (VT:0010420)both adrenal glands wet weight to body weight ratio (CMO:0002411)117385089499753367Rat
4889859Pur28Proteinuria QTL 2819.50.001urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)115892833699753367Rat
724561Plsm4Polydactyly-luxate syndrome (PLS) morphotypes QTL 40.0003forelimb integrity trait (VT:0010562)front foot phalanges count (CMO:0001947)116796218499753367Rat
631506Bp104Blood pressure QTL 1042.8arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)117330831599753367Rat
7411658Foco27Food consumption QTL 2716.20.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)116985594399753367Rat
1549848Bvd6Brain ventricular dilatation QTL 63.10.0001brain ventricle morphology trait (VT:0000822)hydrocephalus severity score (CMO:0001881)117961851999753367Rat

Markers in Region
AU048745  
Rat AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map5q32UniSTS
Cytogenetic Map13q24UniSTS
Cytogenetic Map6q32UniSTS
Cytogenetic Map17p12UniSTS
Cytogenetic Map16p14UniSTS
Cytogenetic Map13q26UniSTS
Cytogenetic Map10q22UniSTS
Cytogenetic Map7q11UniSTS
Cytogenetic Map8q24UniSTS
Cytogenetic Map5q21UniSTS
Cytogenetic Map4q24UniSTS
Cytogenetic Map2q11UniSTS
Cytogenetic Map1q54UniSTS
Cytogenetic Map1q36UniSTS
Cytogenetic Map18p11UniSTS
Cytogenetic Map13q13UniSTS
Cytogenetic Map10q24UniSTS
Cytogenetic Map8q31UniSTS
Cytogenetic Map3q21UniSTS
Cytogenetic Map13p13UniSTS
Cytogenetic Map1q21UniSTS
Cytogenetic Map11q23UniSTS
Cytogenetic Map10q31UniSTS
Cytogenetic Map16q12.2UniSTS
Cytogenetic Map3q24UniSTS
Cytogenetic Map5q36UniSTS
Cytogenetic Map3p13UniSTS
RH127916  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21183,737,174 - 83,737,367 (+)MAPPERmRatBN7.2
mRatBN7.2470,927,050 - 70,927,243 (+)MAPPERmRatBN7.2
Rnor_6.0471,455,520 - 71,455,712NCBIRnor6.0
Rnor_6.01187,986,514 - 87,986,706NCBIRnor6.0
Rnor_5.01191,040,480 - 91,040,672UniSTSRnor5.0
Rnor_5.04136,245,525 - 136,245,717UniSTSRnor5.0
RGSC_v3.4469,802,431 - 69,802,623UniSTSRGSC3.4
RGSC_v3.41185,739,038 - 85,739,230UniSTSRGSC3.4
Celera1182,499,345 - 82,499,537UniSTS
Celera465,866,067 - 65,866,259UniSTS
RH 3.4 Map11729.72UniSTS
Cytogenetic Map11q23UniSTS
RH125835  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21183,738,993 - 83,739,195 (+)MAPPERmRatBN7.2
Rnor_6.01187,988,333 - 87,988,534NCBIRnor6.0
Rnor_5.01191,042,299 - 91,042,500UniSTSRnor5.0
RGSC_v3.41185,740,857 - 85,741,058UniSTSRGSC3.4
Celera1182,501,164 - 82,501,365UniSTS
Cytogenetic Map11q23UniSTS
BI284294  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21183,739,089 - 83,739,293 (+)MAPPERmRatBN7.2
Rnor_6.01187,988,429 - 87,988,632NCBIRnor6.0
Rnor_5.01191,042,395 - 91,042,598UniSTSRnor5.0
RGSC_v3.41185,740,953 - 85,741,156UniSTSRGSC3.4
Celera1182,501,260 - 82,501,463UniSTS
RH 3.4 Map11725.12UniSTS
Cytogenetic Map11q23UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 162 91 90 59 86 59 6 350 186 11 141 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000079595   ⟹   ENSRNOP00000072722
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1197,243,107 - 97,271,713 (-)Ensembl
mRatBN7.2 Ensembl1183,738,874 - 83,767,484 (-)Ensembl
Rnor_6.0 Ensembl1187,988,213 - 88,016,825 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000111204   ⟹   ENSRNOP00000085592
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1197,244,092 - 97,271,713 (-)Ensembl
mRatBN7.2 Ensembl1183,739,859 - 83,767,484 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000121734   ⟹   ENSRNOP00000102528
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1197,244,531 - 97,271,706 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000123069   ⟹   ENSRNOP00000098640
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1197,240,704 - 97,249,162 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000167404   ⟹   ENSRNOP00000105206
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1197,241,090 - 97,249,685 (-)Ensembl
RefSeq Acc Id: NM_001105862   ⟹   NP_001099332
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81197,243,107 - 97,271,713 (-)NCBI
mRatBN7.21183,738,874 - 83,767,484 (-)NCBI
Rnor_6.01187,988,213 - 88,016,825 (-)NCBI
Rnor_5.01191,040,376 - 91,092,856 (-)NCBI
RGSC_v3.41185,740,737 - 85,770,511 (-)RGD
Celera1182,501,044 - 82,529,506 (-)RGD
Sequence:
RefSeq Acc Id: XM_039088073   ⟹   XP_038944001
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81197,241,308 - 97,294,429 (-)NCBI
mRatBN7.21183,737,075 - 83,789,554 (-)NCBI
Protein Sequences
Protein RefSeqs NP_001099332 (Get FASTA)   NCBI Sequence Viewer  
  XP_038944001 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EDL77881 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000072722
  ENSRNOP00000072722.1
  ENSRNOP00000085592.1
  ENSRNOP00000098640.1
  ENSRNOP00000102528.1
  ENSRNOP00000105206.1
RefSeq Acc Id: NP_001099332   ⟸   NM_001105862
- UniProtKB: D4A9X7 (UniProtKB/TrEMBL),   A6JSM6 (UniProtKB/TrEMBL),   A0A8I6GE12 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000072722   ⟸   ENSRNOT00000079595
RefSeq Acc Id: XP_038944001   ⟸   XM_039088073
- Peptide Label: isoform X1
- UniProtKB: D4A9X7 (UniProtKB/TrEMBL),   A6JSM6 (UniProtKB/TrEMBL),   A0A8I6GE12 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000085592   ⟸   ENSRNOT00000111204
Ensembl Acc Id: ENSRNOP00000105206   ⟸   ENSRNOT00000167404
Ensembl Acc Id: ENSRNOP00000102528   ⟸   ENSRNOT00000121734
Ensembl Acc Id: ENSRNOP00000098640   ⟸   ENSRNOT00000123069
Protein Domains
BTB   C2H2-type

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D4A9X7-F1-model_v2 AlphaFold D4A9X7 1-622 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13698331
Promoter ID:EPDNEW_R8856
Type:single initiation site
Name:Hic2_1
Description:HIC ZBTB transcriptional repressor 2
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01188,016,829 - 88,016,889EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1305338 AgrOrtholog
BioCyc Gene G2FUF-20583 BioCyc
Ensembl Genes ENSRNOG00000051458 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000079595 ENTREZGENE
  ENSRNOT00000079595.3 UniProtKB/TrEMBL
  ENSRNOT00000111204.2 UniProtKB/TrEMBL
  ENSRNOT00000121734.1 UniProtKB/TrEMBL
  ENSRNOT00000123069.1 UniProtKB/TrEMBL
  ENSRNOT00000167404.1 UniProtKB/TrEMBL
Gene3D-CATH Classic Zinc Finger UniProtKB/TrEMBL
  Potassium Channel Kv1.1, Chain A UniProtKB/TrEMBL
InterPro BTB/POZ-like UniProtKB/TrEMBL
  BTB/POZ_fold UniProtKB/TrEMBL
  Znf_C2H2/integrase_DNA-bd UniProtKB/TrEMBL
  Znf_C2H2_sf UniProtKB/TrEMBL
  ZnFinger_BTB_dom_contain UniProtKB/TrEMBL
KEGG Report rno:287940 UniProtKB/TrEMBL
NCBI Gene 287940 ENTREZGENE
PANTHER AGAP004733-PA UniProtKB/TrEMBL
  HYPERMETHYLATED IN CANCER 2 PROTEIN UniProtKB/TrEMBL
  ZINC FINGER AND BTB DOMAIN-CONTAINING PROTEIN 44 ISOFORM X1 UniProtKB/TrEMBL
  ZINC FINGER PROTEIN UniProtKB/TrEMBL
Pfam BTB UniProtKB/TrEMBL
  zf-C2H2 UniProtKB/TrEMBL
PharmGKB HIC2 RGD
PhenoGen Hic2 PhenoGen
PROSITE BTB UniProtKB/TrEMBL
  ZINC_FINGER_C2H2_1 UniProtKB/TrEMBL
  ZINC_FINGER_C2H2_2 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000051458 RatGTEx
SMART BTB UniProtKB/TrEMBL
  ZnF_C2H2 UniProtKB/TrEMBL
Superfamily-SCOP BTB/POZ_fold UniProtKB/TrEMBL
  SSF57667 UniProtKB/TrEMBL
UniProt A0A8I6GE12 ENTREZGENE, UniProtKB/TrEMBL
  A0ABK0LCD2_RAT UniProtKB/TrEMBL
  A0ABK0LLH1_RAT UniProtKB/TrEMBL
  A6JSM6 ENTREZGENE, UniProtKB/TrEMBL
  D4A9X7 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-10-12 Hic2  HIC ZBTB transcriptional repressor 2  Hic2  hypermethylated in cancer 2  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 Hic2  hypermethylated in cancer 2   Hic2_predicted  hypermethylated in cancer 2 (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-12 Hic2_predicted  hypermethylated in cancer 2 (predicted)      Symbol and Name status set to approved 70820 APPROVED