Nob1 (NIN1 (RPN12) binding protein 1 homolog) - Rat Genome Database

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Gene: Nob1 (NIN1 (RPN12) binding protein 1 homolog) Rattus norvegicus
Analyze
Symbol: Nob1
Name: NIN1 (RPN12) binding protein 1 homolog
RGD ID: 735222
Description: Predicted to enable RNA endonuclease activity. Predicted to be involved in maturation of SSU-rRNA. Predicted to act upstream of or within visual perception. Predicted to be located in nucleus. Predicted to be part of preribosome, small subunit precursor. Orthologous to human NOB1 (NIN1 (RPN12) binding protein 1 homolog); PARTICIPATES IN ribosome biogenesis pathway; INTERACTS WITH (+)-schisandrin B; 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: LOC291996; MGC156557; nin one binding protein; NIN1/PSMD8 binding protein 1 homolog; NIN1/RPN12 binding protein 1 homolog; NIN1/RPN12 binding protein 1 homolog (S. cerevisiae); Nob1p; RNA-binding protein NOB1
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81952,232,543 - 52,245,824 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1952,232,543 - 52,256,189 (-)EnsemblGRCr8
mRatBN7.21935,322,803 - 35,335,354 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1935,322,669 - 35,346,815 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1942,138,262 - 42,150,724 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01942,791,623 - 42,804,085 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01945,097,502 - 45,109,814 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Dahl_SR_JrHsd1946,019,849 - 46,032,311 (-)NCBIDahl_SR_JrHsd
Lyon_Normotensive1944,144,691 - 44,157,153 (-)NCBILyon_Normotensive
Lyon_Hypertensive1946,018,046 - 46,030,508 (-)NCBILyon_Hypertensive
F344_StmMcwi1943,773,256 - 43,785,718 (-)NCBIF344_StmMcwi
Rnor_6.01938,397,466 - 38,409,924 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1938,397,466 - 38,409,924 (+)Ensemblrn6Rnor6.0
Rnor_5.01949,267,159 - 49,279,617 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41937,278,326 - 37,290,784 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1934,744,223 - 34,756,681 (-)NCBICelera
RGSC_v3.11937,283,206 - 37,295,665 (-)NCBI
Cytogenetic Map19q12NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-schisandrin B  (EXP)
(-)-epigallocatechin 3-gallate  (ISO)
(1->4)-beta-D-glucan  (ISO)
1,2-dimethylhydrazine  (ISO)
17alpha-ethynylestradiol  (EXP)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4-dinitrotoluene  (EXP)
2,6-dinitrotoluene  (EXP)
3-chloropropane-1,2-diol  (EXP)
4,4'-sulfonyldiphenol  (ISO)
6-propyl-2-thiouracil  (EXP)
all-trans-retinoic acid  (ISO)
amitrole  (EXP)
aristolochic acid A  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
benzo[a]pyrene  (ISO)
beta-lapachone  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
caffeine  (ISO)
carbon nanotube  (ISO)
chlorpyrifos  (ISO)
choline  (ISO)
chromium(6+)  (ISO)
cisplatin  (ISO)
clofibric acid  (EXP)
clotrimazole  (EXP)
coumarin  (ISO)
cyclosporin A  (ISO)
cylindrospermopsin  (ISO)
Dibutyl phosphate  (ISO)
dioxygen  (ISO)
diuron  (EXP)
ethanol  (ISO)
folic acid  (ISO)
FR900359  (ISO)
gentamycin  (EXP)
ivermectin  (ISO)
L-methionine  (ISO)
manganese atom  (ISO)
manganese(0)  (ISO)
manganese(II) chloride  (ISO)
N-nitrosodiethylamine  (EXP)
okadaic acid  (ISO)
paracetamol  (ISO)
paraquat  (EXP)
perfluorononanoic acid  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
phenobarbital  (ISO)
pirinixic acid  (ISO)
potassium chromate  (ISO)
pregnenolone 16alpha-carbonitrile  (ISO)
rotenone  (EXP,ISO)
sodium arsenate  (ISO)
sodium arsenite  (ISO)
sulfadimethoxine  (EXP)
sunitinib  (ISO)
tetrachloromethane  (EXP)
thapsigargin  (EXP)
thioacetamide  (EXP)
thiram  (ISO)
titanium dioxide  (ISO)
valproic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Nob1p is required for cleavage of the 3' end of 18S rRNA. Fatica A, etal., Mol Cell Biol 2003 Mar;23(5):1798-807.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. Up-regulation of Nob1 in the rat auditory system with noise-induced hearing loss. Han Y, etal., Neurosci Lett. 2011 Mar 10;491(1):79-82. doi: 10.1016/j.neulet.2011.01.010. Epub 2011 Jan 8.
4. An overview of pre-ribosomal RNA processing in eukaryotes. Henras AK, etal., Wiley Interdiscip Rev RNA. 2015 Mar-Apr;6(2):225-42. doi: 10.1002/wrna.1269. Epub 2014 Oct 27.
5. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
6. GOA pipeline RGD automated data pipeline
7. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
8. Comprehensive gene review and curation RGD comprehensive gene curation
9. Both endonucleolytic and exonucleolytic cleavage mediate ITS1 removal during human ribosomal RNA processing. Sloan KE, etal., J Cell Biol. 2013 Mar 4;200(5):577-88. doi: 10.1083/jcb.201207131. Epub 2013 Feb 25.
10. CK1delta and CK1epsilon are components of human 40S subunit precursors required for cytoplasmic 40S maturation. Zemp I, etal., J Cell Sci. 2014 Mar 15;127(Pt 6):1242-53. doi: 10.1242/jcs.138719. Epub 2014 Jan 14.
Additional References at PubMed
PMID:12477932   PMID:22937111   PMID:23482395  


Genomics

Comparative Map Data
Nob1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81952,232,543 - 52,245,824 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1952,232,543 - 52,256,189 (-)EnsemblGRCr8
mRatBN7.21935,322,803 - 35,335,354 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1935,322,669 - 35,346,815 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1942,138,262 - 42,150,724 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01942,791,623 - 42,804,085 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01945,097,502 - 45,109,814 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Dahl_SR_JrHsd1946,019,849 - 46,032,311 (-)NCBIDahl_SR_JrHsd
Lyon_Normotensive1944,144,691 - 44,157,153 (-)NCBILyon_Normotensive
Lyon_Hypertensive1946,018,046 - 46,030,508 (-)NCBILyon_Hypertensive
F344_StmMcwi1943,773,256 - 43,785,718 (-)NCBIF344_StmMcwi
Rnor_6.01938,397,466 - 38,409,924 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1938,397,466 - 38,409,924 (+)Ensemblrn6Rnor6.0
Rnor_5.01949,267,159 - 49,279,617 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41937,278,326 - 37,290,784 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1934,744,223 - 34,756,681 (-)NCBICelera
RGSC_v3.11937,283,206 - 37,295,665 (-)NCBI
Cytogenetic Map19q12NCBI
NOB1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381669,741,871 - 69,754,926 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1669,741,871 - 69,754,942 (-)Ensemblhg38GRCh38
GRCh371669,775,774 - 69,788,829 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361668,333,275 - 68,346,330 (-)NCBIBuild 36Build 36hg18NCBI36
Celera1654,290,520 - 54,303,578 (-)NCBICelera
Cytogenetic Map16q22.1NCBI
HuRef1655,654,088 - 55,667,425 (-)NCBIHuRef
CHM1_11671,183,740 - 71,196,858 (-)NCBICHM1_1
T2T-CHM13v2.01675,544,399 - 75,557,460 (-)NCBIT2T-CHM13v2.0
Nob1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm398108,139,121 - 108,151,670 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl8108,139,118 - 108,151,683 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm388107,412,489 - 107,425,038 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl8107,412,486 - 107,425,051 (-)Ensemblmm10GRCm38
MGSCv378109,936,389 - 109,948,938 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv368110,301,618 - 110,314,167 (-)NCBIMGSCv36mm8
Celera8111,643,138 - 111,655,687 (-)NCBICelera
Cytogenetic Map8D3NCBI
cM Map854.12NCBI
Nob1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554846,996,797 - 7,006,164 (+)Ensembl
ChiLan1.0NW_0049554846,996,795 - 7,006,499 (+)NCBIChiLan1.0ChiLan1.0
NOB1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21879,292,957 - 79,305,907 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11685,205,139 - 85,217,829 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01650,122,905 - 50,135,096 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11669,506,425 - 69,517,932 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1669,506,425 - 69,517,932 (-)EnsemblpanPan2panpan1.1
NOB1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1579,958,145 - 79,966,166 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl579,945,446 - 79,966,147 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha579,946,907 - 79,955,072 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0580,388,489 - 80,396,668 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl580,388,557 - 80,396,894 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1580,216,290 - 80,224,456 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0579,905,807 - 79,913,960 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0580,538,734 - 80,546,900 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Nob1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934939,780,952 - 39,792,829 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647519,796,296 - 19,808,152 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_00493647519,794,199 - 19,808,142 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
NOB1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl617,233,858 - 17,245,451 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1617,233,863 - 17,245,451 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2616,181,508 - 16,193,098 (-)NCBISscrofa10.2Sscrofa10.2susScr3
NOB1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1557,646,386 - 57,661,014 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl557,646,587 - 57,662,406 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366604720,377,675 - 20,390,841 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Nob1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474616,661,126 - 16,675,962 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462474616,661,039 - 16,672,600 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Nob1
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v11727,141,607 - 27,154,001 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Nob1
93 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:62
Count of miRNA genes:56
Interacting mature miRNAs:58
Transcripts:ENSRNOT00000034386
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
8552935Pigfal10Plasma insulin-like growth factor 1 level QTL 105.7blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)19799775052997750Rat
61447Tcas1Tongue tumor susceptibility QTL 16.08tongue integrity trait (VT:0010553)squamous cell carcinoma of the tongue maximum tumor diameter (CMO:0001875)191922068964220689Rat
9590298Uminl5Urine mineral level QTL 53.590.001urine mineral amount (VT:0015086)urine electrolyte level (CMO:0000593)19799775052997750Rat
631840Niddm38Non-insulin dependent diabetes mellitus QTL 383.86blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)191032907674246245Rat
724546Kidm3Kidney mass QTL 33.1kidney mass (VT:0002707)calculated kidney weight (CMO:0000160)194622677874246245Rat
7411549Bw130Body weight QTL 13050.001body mass (VT:0001259)body weight gain (CMO:0000420)193236531174246245Rat
1331737Uae29Urinary albumin excretion QTL 295.5urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)193628974246245Rat
724518Uae19Urinary albumin excretion QTL 195.5urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)192409397369093973Rat
61423Cia14Collagen induced arthritis QTL 143joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)191083361874246245Rat
2303628Vencon9Ventilatory control QTL 90.005respiration trait (VT:0001943)minute ventilation (CMO:0000132)192318858668188586Rat
2313395Anxrr26Anxiety related response QTL 26aggression-related behavior trait (VT:0015014)tameness/aggressiveness composite score (CMO:0002136)194438513474246245Rat
1578764Stresp19Stress response QTL 193.60.001blood renin amount (VT:0003349)plasma renin activity level (CMO:0000116)193253961574246245Rat
9590090Insglur8Insulin/glucose ratio QTL 810.810.001blood insulin amount (VT:0001560)calculated plasma insulin level (CMO:0002170)19799775052997750Rat
9590250Scort11Serum corticosterone level QTL 1123.450.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)19799775052997750Rat
1331788Rf45Renal function QTL 452.818kidney blood vessel physiology trait (VT:0100012)absolute change in renal blood flow rate (CMO:0001168)193177788874246245Rat
1554318Bmd5Bone mineral density QTL 512.10.0001lumbar vertebra mineral mass (VT:0010511)volumetric bone mineral density (CMO:0001553)192318858668188586Rat
2317848Alcrsp21Alcohol response QTL 211.8999999761581420.05response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)192010930665109306Rat
1354607Gmadr1Adrenal mass QTL 15.83adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)194072709254856850Rat
7247442Uae39Urinary albumin excretion QTL 39urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)19219431774246245Rat
1354600Salc2Saline consumption QTL 29.910.001drinking behavior trait (VT:0001422)saline drink intake rate (CMO:0001627)194072709254856850Rat
1549835Tcas7Tongue tumor susceptibility QTL 70.001tongue integrity trait (VT:0010553)squamous cell carcinoma of the head and neck tumor number (CMO:0001876)194172254674246245Rat
724566Uae12Urinary albumin excretion QTL 125urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)19219431774246245Rat
1354633Bw28Body weight QTL 286.04body mass (VT:0001259)body weight (CMO:0000012)194072709254856850Rat

Markers in Region
RH128393  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21935,322,848 - 35,323,028 (-)MAPPERmRatBN7.2
Rnor_6.01938,409,701 - 38,409,880NCBIRnor6.0
Rnor_5.01949,279,394 - 49,279,573UniSTSRnor5.0
RGSC_v3.41937,278,370 - 37,278,549UniSTSRGSC3.4
Celera1934,744,267 - 34,744,446UniSTS
RH 3.4 Map19314.5UniSTS
Cytogenetic Map19q12UniSTS
AA956531  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr81952,232,578 - 52,232,752 (+)Marker Load Pipeline
mRatBN7.21935,322,839 - 35,323,014 (-)MAPPERmRatBN7.2
Rnor_6.01938,409,715 - 38,409,889NCBIRnor6.0
Rnor_5.01949,279,408 - 49,279,582UniSTSRnor5.0
RGSC_v3.41937,278,361 - 37,278,535UniSTSRGSC3.4
Celera1934,744,258 - 34,744,432UniSTS
RH 3.4 Map19293.7UniSTS
Cytogenetic Map19q12UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 162 91 90 59 92 59 6 356 192 11 141 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000034386   ⟹   ENSRNOP00000031905
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1952,232,543 - 52,256,189 (-)Ensembl
mRatBN7.2 Ensembl1935,322,669 - 35,346,815 (-)Ensembl
Rnor_6.0 Ensembl1938,397,466 - 38,409,924 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000156160   ⟹   ENSRNOP00000099742
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1952,234,951 - 52,245,219 (-)Ensembl
RefSeq Acc Id: NM_199086   ⟹   NP_954517
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81952,232,543 - 52,245,001 (-)NCBI
mRatBN7.21935,322,805 - 35,335,264 (-)NCBI
Dahl_SR_JrHsd1946,019,849 - 46,032,311 (-)NCBI
Lyon_Normotensive1944,144,691 - 44,157,153 (-)NCBI
Lyon_Hypertensive1946,018,046 - 46,030,508 (-)NCBI
F344_StmMcwi1943,773,256 - 43,785,718 (-)NCBI
Rnor_6.01938,397,466 - 38,409,924 (+)NCBI
Rnor_5.01949,267,159 - 49,279,617 (+)NCBI
RGSC_v3.41937,278,326 - 37,290,784 (-)RGD
Celera1934,744,223 - 34,756,681 (-)RGD
Sequence:
RefSeq Acc Id: XM_063277928   ⟹   XP_063133998
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81952,236,156 - 52,245,824 (-)NCBI
RefSeq Acc Id: XM_063277929   ⟹   XP_063133999
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81952,236,156 - 52,245,824 (-)NCBI
Protein Sequences
Protein RefSeqs NP_954517 (Get FASTA)   NCBI Sequence Viewer  
  XP_063133998 (Get FASTA)   NCBI Sequence Viewer  
  XP_063133999 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAI26077 (Get FASTA)   NCBI Sequence Viewer  
  AAQ24170 (Get FASTA)   NCBI Sequence Viewer  
  EDL92479 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000031905
GenBank Protein Q6VEU1 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_954517   ⟸   NM_199086
- UniProtKB: A0JN09 (UniProtKB/Swiss-Prot),   Q6VEU1 (UniProtKB/Swiss-Prot),   A6IZ01 (UniProtKB/TrEMBL),   A0A8L2UKR4 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000031905   ⟸   ENSRNOT00000034386
RefSeq Acc Id: XP_063133999   ⟸   XM_063277929
- Peptide Label: isoform X2
RefSeq Acc Id: XP_063133998   ⟸   XM_063277928
- Peptide Label: isoform X1
Ensembl Acc Id: ENSRNOP00000099742   ⟸   ENSRNOT00000156160
Protein Domains
PIN   PINc

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q6VEU1-F1-model_v2 AlphaFold Q6VEU1 1-410 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13701109
Promoter ID:EPDNEW_R11633
Type:multiple initiation site
Name:Nob1_1
Description:NIN1/PSMD8 binding protein 1 homolog
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01938,397,461 - 38,397,521EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:735222 AgrOrtholog
BioCyc Gene G2FUF-5758 BioCyc
Ensembl Genes ENSRNOG00000021890 Ensembl, ENTREZGENE
Ensembl Transcript ENSRNOT00000034386 ENTREZGENE
Gene3D-CATH 5'-nuclease UniProtKB/Swiss-Prot
  6.20.210.10 UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:8366716 IMAGE-MGC_LOAD
InterPro NOB1 UniProtKB/Swiss-Prot
  Nob1_euk UniProtKB/Swiss-Prot
  NOB1_Zf-like_sf UniProtKB/Swiss-Prot
  NOB1_Zn-bd UniProtKB/Swiss-Prot
  PIN_dom UniProtKB/Swiss-Prot
  Ribonuclease_PIN UniProtKB/Swiss-Prot
  WRNPLPNID UniProtKB/Swiss-Prot
KEGG Report rno:291996 UniProtKB/Swiss-Prot
MGC_CLONE MGC:156557 IMAGE-MGC_LOAD
NCBI Gene 291996 ENTREZGENE
PANTHER PTHR12814 UniProtKB/Swiss-Prot
  RNA-BINDING PROTEIN NOB1 UniProtKB/Swiss-Prot
Pfam NOB1_Zn_bind UniProtKB/Swiss-Prot
  PIN_6 UniProtKB/Swiss-Prot
  WRNPLPNID UniProtKB/Swiss-Prot
PhenoGen Nob1 PhenoGen
PIRSF D-site_20S_pre-rRNA_nuclease UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000021890 RatGTEx
SMART PINc UniProtKB/Swiss-Prot
Superfamily-SCOP SSF144206 UniProtKB/Swiss-Prot
UniProt A0A8L2UKR4 ENTREZGENE, UniProtKB/TrEMBL
  A0ABK0KYB5_RAT UniProtKB/TrEMBL
  A0JN09 ENTREZGENE
  A6IZ01 ENTREZGENE, UniProtKB/TrEMBL
  NOB1_RAT UniProtKB/Swiss-Prot, ENTREZGENE
UniProt Secondary A0JN09 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2018-03-01 Nob1  NIN1 (RPN12) binding protein 1 homolog  Nob1  NIN1/PSMD8 binding protein 1 homolog  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2016-03-29 Nob1  NIN1/PSMD8 binding protein 1 homolog  Nob1  NIN1/RPN12 binding protein 1 homolog  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2015-07-09 Nob1  NIN1/RPN12 binding protein 1 homolog  Nob1  NIN1/RPN12 binding protein 1 homolog (S. cerevisiae)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-03-06 Nob1  NIN1/RPN12 binding protein 1 homolog (S. cerevisiae)  Nob1p  nin one binding protein  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-07-08 Nob1p  nin one binding protein  LOC291996    Symbol updated 1299863 APPROVED