Gene:	Sfrp2 ( Rattus norvegicus ) secreted frizzled-related protein 2
Description:	expression of the mouse homolog is induced by the transcription factor Pax2
Synonyms:	putative secreted frizzled related protein;  (details...)
ArrayIDs:	6596295; 1390119_at; 6534669; 6376839; 1396614_at; A_44_P503116; rc_AA944317_at; A_42_P599969; A_44_P503115; 6411393; 5932948; A_44_P458731; 6419837; 5851468; A_44_P1036291; GE18545;  (details...)
Gene Type:	protein-coding
Additional Data
Homologs
Homo sapiens: SFRP2     See the Human gene in context in:     UCSC     NCBI MapViewer
Mus musculus: Sfrp2     See the Mouse gene in context in:     UCSC     NCBI MapViewer
Comparative Map Data Species Symbol Map Name Chr. Position Rattus norvegicus Sfrp2 Rat Celera Assembly 2 163105863 - 163113579     RGSC genome assembly v3.4 2 175479309 - 175487020     Cytogenetic 2 q34     genome assembly 3.1 2 175435856 - 175436574 Mus musculus Sfrp2 Mouse genome assembly build 36.1 3 83570243 - 83578237     Cytogenetic 3 3 E3 Homo sapiens SFRP2 human genome assembly 4 155059346 - 155067833     Human genome assembly build 36.2 4 154921192 - 154929678     Cytogenetic 4 q31.3   View comparative maps:      NCBI MapViewer
Genome
View:
Browsers:	Select a browser to viewGene (GBrowse)Gene and SNPs (GBrowse)UCSCVCMAPEnsemblNCBIECRVISTAVISTA+UCSC
Annotation
Molecular Function	Gene Ontology Wnt-protein binding,  protein binding (details...)
Biological Process	Gene Ontology multicellular organismal development,  somitogenesis,  negative regulation of mesodermal cell fate specification ...  (details...)
External Links
Databases	DATABASE ID SOURCE SMART: C345C IPI SMART: FRI IPI PROSITE: NTR IPI PROSITE: FZ IPI UNIPARC: UPI0000181598 IPI KEGG Report: rno:310552 ENTREZGENE HomoloGene Group ID: 56438 ENTREZGENE Germonline: 735163 Pfam: Fz IPI Pfam: NTR IPI KEGG Pathway: 04310 ENTREZGENE InterPro: Netrin_domain. IPI InterPro: Frizzled_related. IPI InterPro: Frizzled_dom_subgr. IPI InterPro: Frizzled_Cys-rich. IPI InterPro: Frizzled-like_dom. IPI InterPro: TIMP-like_OB-fold. IPI InterPro: Netrin_module_non-TIMP. IPI Ensembl Protein: ENSRNOP00000012659 IPI IPI: IPI00204804 IPI Gene3D-CATH: Frizzled_Cys-rich IPI Entrez Gene: Sfrp2 ENTREZGENE IMAGE_CLONE: IMAGE:8367121 IMAGE-MGC_LOAD MGC_CLONE: MGC:187620 IMAGE-MGC_LOAD UniProt: B1WBV2_RAT IPI UniProt: Q80W55_RAT IPI Ensembl Genes: ENSRNOG00000009465 IPI Superfamily-SCOP: Frizzled_Cys-rich IPI Superfamily-SCOP: TIMP_like IPI PANTHER: Fz_related IPI
Sequences	Nucleotide: XM_001065174 Get FASTA Search GEO Profiles Nucleotide: NM_001100700 Get FASTA Search GEO Profiles Nucleotide: XM_227314 Get FASTA Search GEO Profiles Nucleotide: CH473976 Get FASTA Search GEO Profiles Nucleotide: AJ560715 Get FASTA Search GEO Profiles Nucleotide: BC161900 Get FASTA Search GEO Profiles (View all 6 Nucleotide Accessions) Protein: CAD90761 Get FASTA Protein: NP_001094170 Get FASTA Protein: EDM00833 Get FASTA Protein: XP_001065174 Get FASTA Protein: Q80W55 Get FASTA Protein: AAI61900 Get FASTA Protein: XP_227314 Get FASTA (View all 7 Protein Accessions)
Clusters	UniGene: 102416
References
Curated References	2 references in RGD related to Sfrp2
Other References	5 other references at PubMed related to Sfrp2
Database Information
RGD ID	735163
History	Date Current Symbol Current Name Previous Symbol Previous name Status Description Reference 08-JUL-05: Sfrp2 secreted frizzled-related protein 2 APPROVED Symbol and Name status set to approved 1299863