Klhl24 (kelch-like family member 24) - Rat Genome Database

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Gene: Klhl24 (kelch-like family member 24) Rattus norvegicus
Analyze
Symbol: Klhl24
Name: kelch-like family member 24
RGD ID: 727971
Description: Predicted to be involved in intermediate filament organization and protein autoubiquitination. Predicted to be located in adherens junction; cytoplasm; and desmosome. Predicted to be part of Cul3-RING ubiquitin ligase complex. Human ortholog(s) of this gene implicated in epidermolysis bullosa simplex and familial hypertrophic cardiomyopathy. Orthologous to human KLHL24 (kelch like family member 24); INTERACTS WITH 17alpha-ethynylestradiol; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: Dre1; kainate receptor-interacting protein for GluR6; kelch-like 24; kelch-like 24 (Drosophila); kelch-like protein 24; KRIP6; MGC105289
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81194,348,024 - 94,382,085 (-)NCBIGRCr8
mRatBN7.21180,843,621 - 80,877,649 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1180,846,755 - 80,877,636 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1189,566,617 - 89,597,436 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01182,219,965 - 82,250,790 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01181,281,103 - 81,311,931 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01184,613,101 - 84,643,674 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1184,615,760 - 84,633,504 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01187,675,249 - 87,705,822 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41183,094,560 - 83,126,617 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11183,152,149 - 83,184,206 (-)NCBI
Celera1179,681,696 - 79,711,857 (-)NCBICelera
Cytogenetic Map11q23NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(-)-alpha-phellandrene  (ISO)
(-)-demecolcine  (ISO)
1,2-dichloroethane  (ISO)
1,2-dimethylhydrazine  (ISO)
17alpha-ethynylestradiol  (EXP)
17beta-estradiol  (EXP,ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2-hydroxypropanoic acid  (ISO)
3,3',4,4'-tetrachlorobiphenyl  (ISO)
3,4-dichloroaniline  (EXP)
4-hydroxyphenyl retinamide  (ISO)
5-aza-2'-deoxycytidine  (ISO)
5-fluorouracil  (ISO)
6-propyl-2-thiouracil  (EXP)
acetamide  (EXP)
aflatoxin B1  (ISO)
all-trans-retinoic acid  (ISO)
alpha-phellandrene  (ISO)
amitrole  (EXP)
ammonium chloride  (EXP)
amphotericin B  (ISO)
antimycin A  (ISO)
arsenite(3-)  (ISO)
arsenous acid  (ISO)
avobenzone  (ISO)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
bisphenol A  (EXP,ISO)
buspirone  (EXP)
butanal  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (EXP,ISO)
cadmium sulfate  (ISO)
captan  (ISO)
carbon nanotube  (ISO)
CGP 52608  (ISO)
cisplatin  (ISO)
cobalt dichloride  (ISO)
copper atom  (EXP,ISO)
copper(0)  (EXP,ISO)
copper(II) sulfate  (ISO)
coumestrol  (ISO)
crocidolite asbestos  (ISO)
curcumin  (ISO)
cyclosporin A  (ISO)
deguelin  (ISO)
diarsenic trioxide  (ISO)
diazinon  (ISO)
dibutyl phthalate  (EXP,ISO)
Didecyldimethylammonium  (ISO)
dioxygen  (ISO)
diuron  (EXP)
dorsomorphin  (ISO)
doxorubicin  (ISO)
elemental selenium  (ISO)
endosulfan  (EXP)
Enterolactone  (ISO)
entinostat  (ISO)
ethanol  (ISO)
ethyl methanesulfonate  (ISO)
fenpyroximate  (ISO)
fenthion  (ISO)
fingolimod hydrochloride  (ISO)
fluoxetine  (ISO)
folpet  (ISO)
formaldehyde  (ISO)
FR900359  (ISO)
gamma-hexachlorocyclohexane  (ISO)
geldanamycin  (ISO)
genistein  (ISO)
gentamycin  (EXP)
hydrogen peroxide  (ISO)
irinotecan  (ISO)
isoprenaline  (ISO)
ketamine  (EXP)
lead(II) chloride  (ISO)
methapyrilene  (EXP)
methidathion  (ISO)
methimazole  (EXP)
methyl methanesulfonate  (ISO)
methylmercury chloride  (ISO)
miconazole  (ISO)
nickel dichloride  (ISO)
niclosamide  (ISO)
oxaliplatin  (EXP)
paracetamol  (ISO)
phenobarbital  (ISO)
phenylephrine  (EXP)
picoxystrobin  (ISO)
pirinixic acid  (ISO)
prednisolone  (ISO)
progesterone  (ISO)
propanal  (ISO)
propiconazole  (ISO)
pyrimidifen  (ISO)
rac-lactic acid  (ISO)
raloxifene  (ISO)
resveratrol  (ISO)
rotenone  (EXP,ISO)
SB 431542  (ISO)
selenium atom  (ISO)
silicon dioxide  (ISO)
silver atom  (ISO)
silver(0)  (ISO)
sirolimus  (ISO)
sodium arsenate  (ISO)
sodium arsenite  (ISO)
sulfadimethoxine  (EXP)
sunitinib  (ISO)
tebufenpyrad  (ISO)
testosterone  (ISO)
testosterone enanthate  (ISO)
tetrachloroethene  (ISO)
tetrachloromethane  (ISO)
thifluzamide  (ISO)
thimerosal  (ISO)
titanium dioxide  (ISO)
topotecan  (EXP)
torcetrapib  (ISO)
tremolite asbestos  (ISO)
trichloroethene  (EXP)
trichostatin A  (ISO)
troglitazone  (ISO)
trovafloxacin  (EXP,ISO)
urethane  (ISO)
valdecoxib  (EXP)
valproic acid  (ISO)
venlafaxine hydrochloride  (EXP)
vinclozolin  (EXP)
vitamin E  (ISO)
vorinostat  (ISO)
zinc atom  (ISO)
zinc(0)  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
adherens junction  (IEA,ISO,ISS)
axon  (IEA)
Cul3-RING ubiquitin ligase complex  (IEA,ISO,ISS)
cytoplasm  (IEA,ISO,ISS)
desmosome  (IEA,ISO,ISS)
perikaryon  (IEA)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. NCBI rat LocusLink and RefSeq merged data October 15, 2003 NCBI rat LocusLink and RefSeq merged data October 15, 2003
2. GOA pipeline RGD automated data pipeline
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:12477932   PMID:15489334   PMID:17254796   PMID:21873635   PMID:27798626   PMID:27889062  


Genomics

Comparative Map Data
Klhl24
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81194,348,024 - 94,382,085 (-)NCBIGRCr8
mRatBN7.21180,843,621 - 80,877,649 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1180,846,755 - 80,877,636 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1189,566,617 - 89,597,436 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01182,219,965 - 82,250,790 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01181,281,103 - 81,311,931 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01184,613,101 - 84,643,674 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1184,615,760 - 84,633,504 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01187,675,249 - 87,705,822 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41183,094,560 - 83,126,617 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11183,152,149 - 83,184,206 (-)NCBI
Celera1179,681,696 - 79,711,857 (-)NCBICelera
Cytogenetic Map11q23NCBI
KLHL24
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh383183,635,623 - 183,684,519 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl3183,635,610 - 183,684,519 (+)EnsemblGRCh38hg38GRCh38
GRCh373183,353,411 - 183,402,307 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 363184,836,105 - 184,885,001 (+)NCBINCBI36Build 36hg18NCBI36
Celera3181,794,950 - 181,843,839 (+)NCBICelera
Cytogenetic Map3q27.1NCBI
HuRef3180,759,268 - 180,810,190 (+)NCBIHuRef
CHM1_13183,317,525 - 183,366,726 (+)NCBICHM1_1
T2T-CHM13v2.03186,445,098 - 186,493,998 (+)NCBIT2T-CHM13v2.0
Klhl24
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391619,916,286 - 19,947,976 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1619,916,292 - 19,947,971 (+)EnsemblGRCm39 Ensembl
GRCm381620,097,553 - 20,129,226 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1620,097,542 - 20,129,221 (+)EnsemblGRCm38mm10GRCm38
MGSCv371620,097,627 - 20,127,817 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361620,011,097 - 20,041,287 (+)NCBIMGSCv36mm8
Celera1620,661,389 - 20,691,296 (+)NCBICelera
Cytogenetic Map16A3NCBI
cM Map1612.36NCBI
Klhl24
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542023,700,035 - 23,735,301 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495542023,700,030 - 23,733,021 (-)NCBIChiLan1.0ChiLan1.0
KLHL24
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22181,505,763 - 181,569,697 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan13181,510,545 - 181,574,403 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v03180,669,767 - 180,731,186 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.13188,837,980 - 188,888,933 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl3188,839,457 - 188,885,385 (+)Ensemblpanpan1.1panPan2
KLHL24
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13416,583,683 - 16,625,778 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3416,590,368 - 16,621,041 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3420,671,915 - 20,713,790 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03416,491,764 - 16,533,422 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3416,491,815 - 16,533,348 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13416,530,507 - 16,572,150 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03416,517,530 - 16,559,186 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03416,755,202 - 16,797,365 (+)NCBIUU_Cfam_GSD_1.0
Klhl24
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405602120,024,263 - 120,061,122 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365786,116,068 - 6,151,297 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365786,116,117 - 6,151,244 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
KLHL24
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl13121,570,591 - 121,608,139 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.113121,564,833 - 121,608,146 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.213131,001,698 - 131,061,043 (+)NCBISscrofa10.2Sscrofa10.2susScr3
KLHL24
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1155,732,347 - 5,780,154 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl155,732,928 - 5,780,143 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366606314,515,358 - 14,565,756 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Klhl24
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473072,807,780 - 72,844,190 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473072,803,070 - 72,843,627 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Klhl24
215 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:94
Count of miRNA genes:78
Interacting mature miRNAs:86
Transcripts:ENSRNOT00000052120
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
724554Iddm17Insulin dependent diabetes mellitus QTL 170.001blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)111897620886241447Rat
724563Uae10Urinary albumin excretion QTL 106urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)112767241082846715Rat
1300110Stl7Serum triglyceride level QTL 74.64blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)112952841882566702Rat
1300135Rf19Renal function QTL 193.38blood creatinine amount (VT:0005328)creatinine clearance (CMO:0000765)114094618882566702Rat
2312566Glom20Glomerulus QTL 203.60.001kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)114428575982566702Rat
1581565Pur10Proteinuria QTL 100.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)114480331882846466Rat
1581572Uae35Urinary albumin excretion QTL 350.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)114480331882846466Rat
724561Plsm4Polydactyly-luxate syndrome (PLS) morphotypes QTL 40.0003forelimb integrity trait (VT:0010562)front foot phalanges count (CMO:0001947)115445753486241447Rat
4889521Gluco62Glucose level QTL 622.820.001blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)115513672982993457Rat
7411658Foco27Food consumption QTL 2716.20.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)115635142486241447Rat
631506Bp104Blood pressure QTL 1042.8arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)115980279482566545Rat
70208Niddm22Non-insulin dependent diabetes mellitus QTL 223.61blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)115980279482566553Rat
10058954Gmadr7Adrenal mass QTL 72.490.0049adrenal gland mass (VT:0010420)both adrenal glands wet weight to body weight ratio (CMO:0002411)116034659086241447Rat
1549848Bvd6Brain ventricular dilatation QTL 63.10.0001brain ventricle morphology trait (VT:0000822)hydrocephalus severity score (CMO:0001881)116611332182169223Rat
634339Niddm50Non-insulin dependent diabetes mellitus QTL 503.32blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)116642214886241447Rat
1354593Stl12Serum triglyceride level QTL 123.36blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)116642214886241447Rat
1354656Bvd3Brain ventricular dilatation QTL 33.640.001brain ventricle morphology trait (VT:0000822)hydrocephalus severity score (CMO:0001881)116944607082846715Rat
10450831Scl80Serum cholesterol level QTL 804.70.01blood LDL cholesterol amount (VT:0000181)blood low density lipoprotein cholesterol level (CMO:0000053)117695713183051965Rat

Markers in Region
AI104888  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21180,873,771 - 80,874,021 (+)MAPPERmRatBN7.2
Rnor_6.01184,639,747 - 84,639,996NCBIRnor6.0
Rnor_5.01187,701,895 - 87,702,144UniSTSRnor5.0
RGSC_v3.41183,122,223 - 83,122,472UniSTSRGSC3.4
Celera1179,708,017 - 79,708,266UniSTS
RH 3.4 Map11686.4UniSTS
Cytogenetic Map11q23UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 42 39 23 19 23 8 11 74 35 41 11 8
Low 1 18 18 18
Below cutoff

Sequence


RefSeq Acc Id: ENSRNOT00000052120   ⟹   ENSRNOP00000050815
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1180,846,755 - 80,877,636 (-)Ensembl
Rnor_6.0 Ensembl1184,615,760 - 84,633,504 (-)Ensembl
RefSeq Acc Id: NM_001394229   ⟹   NP_001381158
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81194,351,157 - 94,382,050 (-)NCBI
mRatBN7.21180,846,754 - 80,877,649 (-)NCBI
RefSeq Acc Id: NM_181473   ⟹   NP_852138
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81194,351,157 - 94,382,050 (-)NCBI
mRatBN7.21180,846,754 - 80,877,649 (-)NCBI
Rnor_6.01184,613,101 - 84,643,674 (-)NCBI
Rnor_5.01187,675,249 - 87,705,822 (-)NCBI
RGSC_v3.41183,094,560 - 83,126,617 (-)RGD
Celera1179,681,696 - 79,711,857 (-)RGD
Sequence:
RefSeq Acc Id: XM_039088275   ⟹   XP_038944203
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81194,348,024 - 94,381,998 (-)NCBI
mRatBN7.21180,843,621 - 80,876,680 (-)NCBI
RefSeq Acc Id: XM_039088276   ⟹   XP_038944204
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81194,348,024 - 94,381,374 (-)NCBI
mRatBN7.21180,843,621 - 80,876,889 (-)NCBI
RefSeq Acc Id: XM_063270469   ⟹   XP_063126539
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81194,348,024 - 94,381,998 (-)NCBI
RefSeq Acc Id: XM_063270470   ⟹   XP_063126540
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81194,348,024 - 94,381,962 (-)NCBI
RefSeq Acc Id: XM_063270471   ⟹   XP_063126541
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81194,348,024 - 94,381,937 (-)NCBI
RefSeq Acc Id: XM_063270472   ⟹   XP_063126542
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81194,348,024 - 94,382,085 (-)NCBI
RefSeq Acc Id: XM_063270473   ⟹   XP_063126543
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81194,348,024 - 94,381,998 (-)NCBI
RefSeq Acc Id: NP_852138   ⟸   NM_181473
- UniProtKB: Q812D9 (UniProtKB/Swiss-Prot),   Q56A24 (UniProtKB/Swiss-Prot),   A6JSC2 (UniProtKB/TrEMBL),   F1LNL5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000050815   ⟸   ENSRNOT00000052120
RefSeq Acc Id: XP_038944204   ⟸   XM_039088276
- Peptide Label: isoform X1
- UniProtKB: Q56A24 (UniProtKB/Swiss-Prot),   Q812D9 (UniProtKB/Swiss-Prot),   A6JSC2 (UniProtKB/TrEMBL),   F1LNL5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038944203   ⟸   XM_039088275
- Peptide Label: isoform X1
- UniProtKB: Q56A24 (UniProtKB/Swiss-Prot),   Q812D9 (UniProtKB/Swiss-Prot),   A6JSC2 (UniProtKB/TrEMBL),   F1LNL5 (UniProtKB/TrEMBL)
RefSeq Acc Id: NP_001381158   ⟸   NM_001394229
- UniProtKB: Q56A24 (UniProtKB/Swiss-Prot),   Q812D9 (UniProtKB/Swiss-Prot),   A6JSC2 (UniProtKB/TrEMBL),   F1LNL5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063126542   ⟸   XM_063270472
- Peptide Label: isoform X1
RefSeq Acc Id: XP_063126539   ⟸   XM_063270469
- Peptide Label: isoform X1
RefSeq Acc Id: XP_063126543   ⟸   XM_063270473
- Peptide Label: isoform X1
RefSeq Acc Id: XP_063126540   ⟸   XM_063270470
- Peptide Label: isoform X1
RefSeq Acc Id: XP_063126541   ⟸   XM_063270471
- Peptide Label: isoform X1
Protein Domains
BACK   BTB

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q56A24-F1-model_v2 AlphaFold Q56A24 1-600 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:727971 AgrOrtholog
BioCyc Gene G2FUF-20711 BioCyc
Ensembl Genes ENSRNOG00000033372 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ENSRNOG00055004730 UniProtKB/Swiss-Prot
  ENSRNOG00060011991 UniProtKB/Swiss-Prot
  ENSRNOG00065004385 UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000052120 ENTREZGENE, UniProtKB/TrEMBL
  ENSRNOT00000052120.6 UniProtKB/Swiss-Prot
  ENSRNOT00055007517 UniProtKB/Swiss-Prot
  ENSRNOT00060020326 UniProtKB/Swiss-Prot
  ENSRNOT00065006381 UniProtKB/Swiss-Prot
Gene3D-CATH 1.25.40.420 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  2.120.10.80 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7312023 IMAGE-MGC_LOAD
InterPro BACK UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  BTB-kelch_protein UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  BTB/POZ_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Kelch-typ_b-propeller UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Kelch_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  KLHL24 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  KLHL24_BACK UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SKP1/BTB/POZ_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:303803 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGC_CLONE MGC:105289 IMAGE-MGC_LOAD
NCBI Gene 303803 ENTREZGENE
PANTHER KELCH PROTEIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR24412:SF215 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam BACK UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  BTB UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Kelch_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Klhl24 PhenoGen
PIRSF Kelch-like_protein_gigaxonin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE BTB UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RatGTEx ENSRNOG00000033372 RatGTEx
  ENSRNOG00055004730 RatGTEx
  ENSRNOG00060011991 RatGTEx
  ENSRNOG00065004385 RatGTEx
SMART BACK UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  BTB UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Kelch UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF117281 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF54695 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A6JSC2 ENTREZGENE, UniProtKB/TrEMBL
  F1LNL5 ENTREZGENE, UniProtKB/TrEMBL
  KLH24_RAT UniProtKB/Swiss-Prot, ENTREZGENE
  Q812D9 ENTREZGENE
UniProt Secondary Q812D9 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2013-02-27 Klhl24  kelch-like family member 24  Klhl24  kelch-like 24 (Drosophila)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-03-30 Klhl24  kelch-like 24 (Drosophila)  Dre1  Dre1 protein  Symbol and Name updated 1299863 APPROVED
2005-07-08 Dre1  Dre1 protein      Symbol and Name status set to approved 1299863 APPROVED