Klhl24 (kelch-like family member 24) - Rat Genome Database

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Gene: Klhl24 (kelch-like family member 24) Rattus norvegicus
Analyze
Symbol: Klhl24
Name: kelch-like family member 24
RGD ID: 727971
Description: Predicted to enable ubiquitin-like ligase-substrate adaptor activity. Predicted to be involved in intermediate filament organization; proteasome-mediated ubiquitin-dependent protein catabolic process; and protein autoubiquitination. Predicted to be located in adherens junction and desmosome. Predicted to be part of Cul3-RING ubiquitin ligase complex. Predicted to be active in cytoplasm. Human ortholog(s) of this gene implicated in epidermolysis bullosa simplex and familial hypertrophic cardiomyopathy. Orthologous to human KLHL24 (kelch like family member 24); INTERACTS WITH 17alpha-ethynylestradiol; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: Dre1; kainate receptor-interacting protein for GluR6; kelch-like 24; kelch-like 24 (Drosophila); kelch-like protein 24; KRIP6; MGC105289
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81194,348,024 - 94,382,085 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1194,351,157 - 94,382,050 (-)EnsemblGRCr8
mRatBN7.21180,843,621 - 80,877,649 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1180,846,755 - 80,877,636 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1189,566,617 - 89,597,436 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01182,219,965 - 82,250,790 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01181,281,103 - 81,311,931 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01184,613,101 - 84,643,674 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1184,615,760 - 84,633,504 (-)Ensemblrn6Rnor6.0
Rnor_5.01187,675,249 - 87,705,822 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41183,094,560 - 83,126,617 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1179,681,696 - 79,711,857 (-)NCBICelera
RGSC_v3.11183,152,149 - 83,184,206 (-)NCBI
Cytogenetic Map11q23NCBI
JBrowse:




Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(-)-alpha-phellandrene  (ISO)
(-)-demecolcine  (ISO)
1,2-dichloroethane  (ISO)
1,2-dimethylhydrazine  (ISO)
17alpha-ethynylestradiol  (EXP)
17beta-estradiol  (EXP,ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2-hydroxypropanoic acid  (ISO)
3,3',4,4'-tetrachlorobiphenyl  (ISO)
3,4-dichloroaniline  (EXP)
4,4'-sulfonyldiphenol  (ISO)
4-hydroxyphenyl retinamide  (ISO)
5-aza-2'-deoxycytidine  (ISO)
5-fluorouracil  (ISO)
6-propyl-2-thiouracil  (EXP)
acetamide  (EXP)
actinomycin D  (ISO)
aflatoxin B1  (ISO)
all-trans-retinoic acid  (ISO)
alpha-phellandrene  (ISO)
amitrole  (EXP)
ammonium chloride  (EXP)
amphotericin B  (ISO)
antimycin A  (ISO)
arsenite(3-)  (ISO)
arsenous acid  (ISO)
avobenzone  (ISO)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
buspirone  (EXP)
butanal  (ISO)
Butylbenzyl phthalate  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (EXP,ISO)
cadmium sulfate  (ISO)
captan  (ISO)
carbon nanotube  (ISO)
CGP 52608  (ISO)
cisplatin  (ISO)
cobalt dichloride  (ISO)
copper atom  (EXP,ISO)
copper(0)  (EXP,ISO)
copper(II) sulfate  (ISO)
coumestrol  (ISO)
crocidolite asbestos  (ISO)
curcumin  (ISO)
cyclosporin A  (ISO)
DDE  (ISO)
deguelin  (ISO)
diarsenic trioxide  (ISO)
diazinon  (ISO)
Dibutyl phosphate  (ISO)
dibutyl phthalate  (EXP,ISO)
Didecyldimethylammonium  (ISO)
dimethyl sulfoxide  (ISO)
dioxygen  (ISO)
diuron  (EXP)
dorsomorphin  (ISO)
doxorubicin  (ISO)
elemental selenium  (ISO)
endosulfan  (EXP)
Enterolactone  (ISO)
entinostat  (ISO)
ethanol  (ISO)
ethyl methanesulfonate  (ISO)
fenpyroximate  (ISO)
fenthion  (ISO)
fingolimod hydrochloride  (ISO)
fluoxetine  (ISO)
folpet  (ISO)
formaldehyde  (ISO)
FR900359  (ISO)
gamma-hexachlorocyclohexane  (ISO)
geldanamycin  (ISO)
genistein  (ISO)
gentamycin  (EXP)
GSK-J4  (ISO)
hydrogen peroxide  (ISO)
irinotecan  (ISO)
isoprenaline  (ISO)
ketamine  (EXP)
lead(II) chloride  (ISO)
methapyrilene  (EXP)
methidathion  (ISO)
methimazole  (EXP)
methyl methanesulfonate  (ISO)
methylmercury chloride  (ISO)
miconazole  (ISO)
nickel dichloride  (ISO)
niclosamide  (ISO)
Nutlin-3  (ISO)
okadaic acid  (ISO)
oxaliplatin  (EXP)
paracetamol  (ISO)
phenobarbital  (ISO)
phenylephrine  (EXP)
picoxystrobin  (ISO)
pirinixic acid  (ISO)
prednisolone  (ISO)
progesterone  (ISO)
propanal  (ISO)
propiconazole  (ISO)
pyrimidifen  (ISO)
rac-lactic acid  (ISO)
raloxifene  (ISO)
resveratrol  (ISO)
rotenone  (EXP,ISO)
SB 431542  (ISO)
selenium atom  (ISO)
silicon dioxide  (ISO)
silver atom  (ISO)
silver(0)  (ISO)
sirolimus  (ISO)
sodium arsenate  (ISO)
sodium arsenite  (ISO)
sulfadimethoxine  (EXP)
sunitinib  (ISO)
tebufenpyrad  (ISO)
testosterone  (ISO)
testosterone enanthate  (ISO)
tetrachloroethene  (ISO)
tetrachloromethane  (ISO)
thifluzamide  (ISO)
thimerosal  (ISO)
thiram  (ISO)
titanium dioxide  (ISO)
topotecan  (EXP)
torcetrapib  (ISO)
tremolite asbestos  (ISO)
trichloroethene  (EXP)
trichostatin A  (ISO)
troglitazone  (ISO)
trovafloxacin  (EXP,ISO)
urethane  (ISO)
valdecoxib  (EXP)
valproic acid  (ISO)
venlafaxine hydrochloride  (EXP)
vinclozolin  (EXP)
vitamin E  (ISO)
vorinostat  (ISO)
zinc atom  (ISO)
zinc(0)  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
adherens junction  (IEA,ISO,ISS)
axon  (IEA)
Cul3-RING ubiquitin ligase complex  (IBA,IEA,ISO,ISS)
cytoplasm  (IBA,IEA,ISO,ISS)
desmosome  (IEA,ISO,ISS)
perikaryon  (IEA)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. NCBI rat LocusLink and RefSeq merged data October 15, 2003 NCBI rat LocusLink and RefSeq merged data October 15, 2003
2. GOA pipeline RGD automated data pipeline
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:12477932   PMID:15489334   PMID:17254796   PMID:21873635   PMID:27798626   PMID:27889062  


Genomics

Comparative Map Data
Klhl24
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81194,348,024 - 94,382,085 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1194,351,157 - 94,382,050 (-)EnsemblGRCr8
mRatBN7.21180,843,621 - 80,877,649 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1180,846,755 - 80,877,636 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1189,566,617 - 89,597,436 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01182,219,965 - 82,250,790 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01181,281,103 - 81,311,931 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01184,613,101 - 84,643,674 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1184,615,760 - 84,633,504 (-)Ensemblrn6Rnor6.0
Rnor_5.01187,675,249 - 87,705,822 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41183,094,560 - 83,126,617 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1179,681,696 - 79,711,857 (-)NCBICelera
RGSC_v3.11183,152,149 - 83,184,206 (-)NCBI
Cytogenetic Map11q23NCBI
KLHL24
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh383183,635,623 - 183,684,519 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl3183,635,602 - 183,684,519 (+)Ensemblhg38GRCh38
GRCh373183,353,411 - 183,402,307 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 363184,836,105 - 184,885,001 (+)NCBIBuild 36Build 36hg18NCBI36
Celera3181,794,950 - 181,843,839 (+)NCBICelera
Cytogenetic Map3q27.1NCBI
HuRef3180,759,268 - 180,810,190 (+)NCBIHuRef
CHM1_13183,317,525 - 183,366,726 (+)NCBICHM1_1
T2T-CHM13v2.03186,445,098 - 186,493,998 (+)NCBIT2T-CHM13v2.0
Klhl24
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391619,916,286 - 19,947,976 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1619,916,292 - 19,947,971 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm381620,097,553 - 20,129,226 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1620,097,542 - 20,129,221 (+)Ensemblmm10GRCm38
MGSCv371620,097,627 - 20,127,817 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361620,011,097 - 20,041,287 (+)NCBIMGSCv36mm8
Celera1620,661,389 - 20,691,296 (+)NCBICelera
Cytogenetic Map16A3NCBI
cM Map1612.36NCBI
Klhl24
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542023,700,035 - 23,735,301 (-)Ensembl
ChiLan1.0NW_00495542023,700,030 - 23,733,021 (-)NCBIChiLan1.0ChiLan1.0
KLHL24
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22181,505,763 - 181,569,697 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan13181,510,545 - 181,574,403 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v03180,669,767 - 180,731,186 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.13188,837,980 - 188,888,933 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl3188,839,457 - 188,885,385 (+)EnsemblpanPan2panpan1.1
KLHL24
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13416,583,683 - 16,625,778 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3416,590,368 - 16,621,041 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha3420,671,915 - 20,713,790 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.03416,491,764 - 16,533,422 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3416,491,815 - 16,533,348 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13416,530,507 - 16,572,150 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03416,517,530 - 16,559,186 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03416,755,202 - 16,797,365 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Klhl24
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405602120,024,263 - 120,061,122 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365786,116,068 - 6,151,297 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049365786,116,117 - 6,151,244 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
KLHL24
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl13121,570,591 - 121,608,139 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.113121,564,833 - 121,608,146 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.213131,001,698 - 131,061,043 (+)NCBISscrofa10.2Sscrofa10.2susScr3
KLHL24
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1155,732,347 - 5,780,154 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl155,732,928 - 5,780,143 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366606314,515,358 - 14,565,756 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Klhl24
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473072,807,780 - 72,844,190 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462473072,803,070 - 72,843,627 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Klhl24
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v144,900,156 - 4,930,071 (+)NCBIRrattus_CSIRO_v1

miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:94
Count of miRNA genes:78
Interacting mature miRNAs:86
Transcripts:ENSRNOT00000052120
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
70208Niddm22Non-insulin dependent diabetes mellitus QTL 223.61blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)117330848796070872Rat
1581565Pur10Proteinuria QTL 100.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)115827236396350770Rat
4889859Pur28Proteinuria QTL 2819.50.001urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)115892833699753367Rat
1549848Bvd6Brain ventricular dilatation QTL 63.10.0001brain ventricle morphology trait (VT:0000822)hydrocephalus severity score (CMO:0001881)117961851999753367Rat
10450831Scl80Serum cholesterol level QTL 804.70.01blood LDL cholesterol amount (VT:0000181)blood low density lipoprotein cholesterol level (CMO:0000053)119046178196556255Rat
10058954Gmadr7Adrenal mass QTL 72.490.0049adrenal gland mass (VT:0010420)both adrenal glands wet weight to body weight ratio (CMO:0002411)117385089499753367Rat
1300135Rf19Renal function QTL 193.38blood creatinine amount (VT:0005328)creatinine clearance (CMO:0000765)115441539196071021Rat
1354656Bvd3Brain ventricular dilatation QTL 33.640.001brain ventricle morphology trait (VT:0000822)hydrocephalus severity score (CMO:0001881)118295102896351019Rat
2312566Glom20Glomerulus QTL 203.60.001kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)115775483796071021Rat
724563Uae10Urinary albumin excretion QTL 106urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)112019354996351019Rat
724561Plsm4Polydactyly-luxate syndrome (PLS) morphotypes QTL 40.0003forelimb integrity trait (VT:0010562)front foot phalanges count (CMO:0001947)116796218499753367Rat
4889521Gluco62Glucose level QTL 622.820.001blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)116859932196497754Rat
7411658Foco27Food consumption QTL 2716.20.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)116985594399753367Rat
631506Bp104Blood pressure QTL 1042.8arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)117330831599753367Rat
1581572Uae35Urinary albumin excretion QTL 350.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)115827236396350770Rat
1300110Stl7Serum triglyceride level QTL 74.64blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)115107102196071021Rat

Markers in Region
AI104888  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21180,873,771 - 80,874,021 (+)MAPPERmRatBN7.2
Rnor_6.01184,639,747 - 84,639,996NCBIRnor6.0
Rnor_5.01187,701,895 - 87,702,144UniSTSRnor5.0
RGSC_v3.41183,122,223 - 83,122,472UniSTSRGSC3.4
Celera1179,708,017 - 79,708,266UniSTS
RH 3.4 Map11686.4UniSTS
Cytogenetic Map11q23UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 165 91 90 59 92 59 6 356 192 11 144 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000052120   ⟹   ENSRNOP00000050815
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1194,351,157 - 94,382,050 (-)Ensembl
mRatBN7.2 Ensembl1180,846,755 - 80,877,636 (-)Ensembl
Rnor_6.0 Ensembl1184,615,760 - 84,633,504 (-)Ensembl
RefSeq Acc Id: NM_001394229   ⟹   NP_001381158
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81194,351,157 - 94,382,050 (-)NCBI
mRatBN7.21180,846,754 - 80,877,649 (-)NCBI
RefSeq Acc Id: NM_181473   ⟹   NP_852138
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81194,351,157 - 94,382,050 (-)NCBI
mRatBN7.21180,846,754 - 80,877,649 (-)NCBI
Rnor_6.01184,613,101 - 84,643,674 (-)NCBI
Rnor_5.01187,675,249 - 87,705,822 (-)NCBI
RGSC_v3.41183,094,560 - 83,126,617 (-)RGD
Celera1179,681,696 - 79,711,857 (-)RGD
Sequence:
RefSeq Acc Id: XM_039088275   ⟹   XP_038944203
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81194,348,024 - 94,381,998 (-)NCBI
mRatBN7.21180,843,621 - 80,876,680 (-)NCBI
RefSeq Acc Id: XM_039088276   ⟹   XP_038944204
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81194,348,024 - 94,381,374 (-)NCBI
mRatBN7.21180,843,621 - 80,876,889 (-)NCBI
RefSeq Acc Id: XM_063270469   ⟹   XP_063126539
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81194,348,024 - 94,381,998 (-)NCBI
RefSeq Acc Id: XM_063270470   ⟹   XP_063126540
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81194,348,024 - 94,381,962 (-)NCBI
RefSeq Acc Id: XM_063270471   ⟹   XP_063126541
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81194,348,024 - 94,381,937 (-)NCBI
RefSeq Acc Id: XM_063270472   ⟹   XP_063126542
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81194,348,024 - 94,382,085 (-)NCBI
RefSeq Acc Id: XM_063270473   ⟹   XP_063126543
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81194,348,024 - 94,381,998 (-)NCBI
RefSeq Acc Id: NP_852138   ⟸   NM_181473
- UniProtKB: Q812D9 (UniProtKB/Swiss-Prot),   Q56A24 (UniProtKB/Swiss-Prot),   A6JSC2 (UniProtKB/TrEMBL),   F1LNL5 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000050815   ⟸   ENSRNOT00000052120
RefSeq Acc Id: XP_038944204   ⟸   XM_039088276
- Peptide Label: isoform X1
- UniProtKB: Q56A24 (UniProtKB/Swiss-Prot),   Q812D9 (UniProtKB/Swiss-Prot),   A6JSC2 (UniProtKB/TrEMBL),   F1LNL5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038944203   ⟸   XM_039088275
- Peptide Label: isoform X1
- UniProtKB: Q56A24 (UniProtKB/Swiss-Prot),   Q812D9 (UniProtKB/Swiss-Prot),   A6JSC2 (UniProtKB/TrEMBL),   F1LNL5 (UniProtKB/TrEMBL)
RefSeq Acc Id: NP_001381158   ⟸   NM_001394229
- UniProtKB: Q56A24 (UniProtKB/Swiss-Prot),   Q812D9 (UniProtKB/Swiss-Prot),   A6JSC2 (UniProtKB/TrEMBL),   F1LNL5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063126542   ⟸   XM_063270472
- Peptide Label: isoform X1
- UniProtKB: Q812D9 (UniProtKB/Swiss-Prot),   Q56A24 (UniProtKB/Swiss-Prot),   A6JSC2 (UniProtKB/TrEMBL),   F1LNL5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063126539   ⟸   XM_063270469
- Peptide Label: isoform X1
- UniProtKB: Q812D9 (UniProtKB/Swiss-Prot),   Q56A24 (UniProtKB/Swiss-Prot),   A6JSC2 (UniProtKB/TrEMBL),   F1LNL5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063126543   ⟸   XM_063270473
- Peptide Label: isoform X1
- UniProtKB: Q812D9 (UniProtKB/Swiss-Prot),   Q56A24 (UniProtKB/Swiss-Prot),   A6JSC2 (UniProtKB/TrEMBL),   F1LNL5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063126540   ⟸   XM_063270470
- Peptide Label: isoform X1
- UniProtKB: Q812D9 (UniProtKB/Swiss-Prot),   Q56A24 (UniProtKB/Swiss-Prot),   A6JSC2 (UniProtKB/TrEMBL),   F1LNL5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063126541   ⟸   XM_063270471
- Peptide Label: isoform X1
- UniProtKB: Q812D9 (UniProtKB/Swiss-Prot),   Q56A24 (UniProtKB/Swiss-Prot),   A6JSC2 (UniProtKB/TrEMBL),   F1LNL5 (UniProtKB/TrEMBL)
Protein Domains
BACK   BTB

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q56A24-F1-model_v2 AlphaFold Q56A24 1-600 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:727971 AgrOrtholog
BioCyc Gene G2FUF-20711 BioCyc
Ensembl Genes ENSRNOG00000033372 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000052120 ENTREZGENE
  ENSRNOT00000052120.6 UniProtKB/Swiss-Prot
Gene3D-CATH 1.25.40.420 UniProtKB/Swiss-Prot
  2.120.10.80 UniProtKB/Swiss-Prot
  Potassium Channel Kv1.1, Chain A UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:7312023 IMAGE-MGC_LOAD
InterPro BACK UniProtKB/Swiss-Prot
  BTB-kelch_protein UniProtKB/Swiss-Prot
  BTB/POZ_dom UniProtKB/Swiss-Prot
  Kelch-typ_b-propeller UniProtKB/Swiss-Prot
  Kelch_1 UniProtKB/Swiss-Prot
  KLHL24 UniProtKB/Swiss-Prot
  KLHL24_BACK UniProtKB/Swiss-Prot
  SKP1/BTB/POZ_sf UniProtKB/Swiss-Prot
KEGG Report rno:303803 UniProtKB/Swiss-Prot
MGC_CLONE MGC:105289 IMAGE-MGC_LOAD
NCBI Gene 303803 ENTREZGENE
PANTHER KELCH PROTEIN UniProtKB/Swiss-Prot
  PTHR24412:SF215 UniProtKB/Swiss-Prot
Pfam BACK UniProtKB/Swiss-Prot
  BTB UniProtKB/Swiss-Prot
  Kelch_1 UniProtKB/Swiss-Prot
  Kelch_KLHDC2_KLHL20_DRC7 UniProtKB/Swiss-Prot
PhenoGen Klhl24 PhenoGen
PIRSF Kelch-like_protein_gigaxonin UniProtKB/Swiss-Prot
PROSITE BTB UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000033372 RatGTEx
SMART BACK UniProtKB/Swiss-Prot
  BTB UniProtKB/Swiss-Prot
  Kelch UniProtKB/Swiss-Prot
Superfamily-SCOP SSF117281 UniProtKB/Swiss-Prot
  SSF54695 UniProtKB/Swiss-Prot
UniProt A6JSC2 ENTREZGENE, UniProtKB/TrEMBL
  F1LNL5 ENTREZGENE, UniProtKB/TrEMBL
  KLH24_RAT UniProtKB/Swiss-Prot, ENTREZGENE
  Q812D9 ENTREZGENE
UniProt Secondary Q812D9 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2013-02-27 Klhl24  kelch-like family member 24  Klhl24  kelch-like 24 (Drosophila)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-03-30 Klhl24  kelch-like 24 (Drosophila)  Dre1  Dre1 protein  Symbol and Name updated 1299863 APPROVED
2005-07-08 Dre1  Dre1 protein      Symbol and Name status set to approved 1299863 APPROVED