Cct4 (chaperonin containing TCP1 subunit 4) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Behavioral & Substance Use Disorder Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)
Gene: Cct4 (chaperonin containing TCP1 subunit 4) Rattus norvegicus
Analyze
Symbol: Cct4
Name: chaperonin containing TCP1 subunit 4
RGD ID: 727937
Description: Predicted to enable protein folding chaperone and unfolded protein binding activity. Predicted to be involved in positive regulation of telomerase RNA localization to Cajal body; protein folding; and protein stabilization. Predicted to act upstream of with a positive effect on scaRNA localization to Cajal body. Predicted to act upstream of or within binding activity of sperm to zona pellucida. Predicted to be located in cell body; centrosome; and microtubule. Predicted to be part of chaperonin-containing T-complex and zona pellucida receptor complex. Used to study hereditary sensory neuropathy. Orthologous to human CCT4 (chaperonin containing TCP1 subunit 4); INTERACTS WITH 1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane; 17alpha-ethynylestradiol; 17beta-estradiol.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: CCT-delta; chaperonin containing Tcp1, subunit 4 (delta); chaperonin subunit 4 (delta); T-complex protein 1 subunit delta; TCP-1-delta
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr814101,193,057 - 101,205,935 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl14101,192,772 - 101,205,770 (+)EnsemblGRCr8
mRatBN7.21496,991,853 - 97,004,732 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1496,991,859 - 97,005,267 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx14101,325,100 - 101,337,974 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.014102,567,399 - 102,580,273 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01499,039,002 - 99,051,876 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.014107,767,392 - 107,780,270 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl14107,767,392 - 107,780,270 (+)Ensemblrn6Rnor6.0
Rnor_5.014107,843,411 - 107,856,260 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.414103,675,110 - 103,687,893 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1495,973,133 - 95,985,983 (+)NCBICelera
RGSC_v3.114103,694,320 - 103,707,104 (+)NCBI
Cytogenetic Map14q22NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane  (EXP,ISO)
1,2-dimethylhydrazine  (ISO)
1-chloro-2,4-dinitrobenzene  (ISO)
17alpha-ethynylestradiol  (EXP,ISO)
17beta-estradiol  (EXP)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4-dibromophenyl 2,4,5-tribromophenyl ether  (EXP)
2,6-dimethoxyphenol  (ISO)
2,6-dinitrotoluene  (EXP)
3-chloropropane-1,2-diol  (EXP)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
4,4'-sulfonyldiphenol  (ISO)
acrylamide  (EXP,ISO)
all-trans-retinoic acid  (ISO)
aminoglutethimide  (ISO)
antirheumatic drug  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenite(3-)  (ISO)
benzo[a]pyrene  (ISO)
benzo[e]pyrene  (ISO)
beta-naphthoflavone  (ISO)
bisphenol A  (EXP,ISO)
bisphenol AF  (ISO)
Bisphenol B  (ISO)
bisphenol F  (ISO)
caffeine  (ISO)
cannabidiol  (ISO)
carbon nanotube  (ISO)
casticin  (ISO)
CGP 52608  (ISO)
chromium(6+)  (ISO)
crocidolite asbestos  (ISO)
Cuprizon  (ISO)
cyclosporin A  (ISO)
DDE  (ISO)
dexamethasone  (ISO)
Dibutyl phosphate  (ISO)
dinophysistoxin 1  (ISO)
doxorubicin  (ISO)
endosulfan  (EXP)
enzyme inhibitor  (ISO)
finasteride  (EXP)
flutamide  (EXP)
folic acid  (ISO)
furan  (EXP)
furfural  (ISO)
gentamycin  (EXP)
glyphosate  (ISO)
hyaluronic acid  (EXP)
hydrogen peroxide  (EXP)
indirubin  (ISO)
indometacin  (ISO)
ivermectin  (ISO)
L-serine  (ISO)
manganese atom  (ISO)
manganese(0)  (ISO)
manganese(II) chloride  (ISO)
methapyrilene  (ISO)
nefazodone  (EXP)
nimesulide  (EXP)
okadaic acid  (ISO)
paraquat  (EXP)
pentachlorophenol  (ISO)
phenethyl isothiocyanate  (EXP)
PhIP  (EXP)
propiconazole  (ISO)
Propiverine  (EXP)
resveratrol  (EXP)
rotenone  (EXP)
SB 431542  (ISO)
sodium arsenite  (ISO)
sodium chloride  (ISO)
sulindac  (EXP)
tetrachloromethane  (EXP,ISO)
thiram  (ISO)
titanium dioxide  (ISO)
trimellitic anhydride  (ISO)
triphenyl phosphate  (ISO)
valdecoxib  (EXP)
valproic acid  (ISO)
zinc sulfate  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cell body  (IEA,ISO)
centrosome  (IEA,ISO)
chaperonin-containing T-complex  (IBA,IEA,ISO,ISS)
cytoplasm  (IEA)
cytosol  (IEA,ISO)
melanosome  (IEA)
microtubule  (IEA,ISO)
zona pellucida receptor complex  (IEA,ISO)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Normalization and subtraction: two approaches to facilitate gene discovery. Bonaldo MF, etal., Genome Res 1996 Sep;6(9):791-806.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. Hereditary sensory neuropathy is caused by a mutation in the delta subunit of the cytosolic chaperonin-containing t-complex peptide-1 (Cct4 ) gene. Lee MJ, etal., Hum Mol Genet 2003 Aug 1;12(15):1917-25.
4. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
5. NCBI rat LocusLink and RefSeq merged data October 15, 2003 NCBI rat LocusLink and RefSeq merged data October 15, 2003
6. GOA pipeline RGD automated data pipeline
7. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
8. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
Additional References at PubMed
PMID:7828721   PMID:7953530   PMID:15193290   PMID:15489334   PMID:16854843   PMID:20080638   PMID:20193073   PMID:20458337   PMID:21525035   PMID:21880732   PMID:22658674   PMID:23011926  
PMID:23376485   PMID:23533145   PMID:23716698   PMID:24625528   PMID:25124038   PMID:25467444   PMID:26316108   PMID:29476059   PMID:32357304   PMID:33450132  


Genomics

Comparative Map Data
Cct4
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr814101,193,057 - 101,205,935 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl14101,192,772 - 101,205,770 (+)EnsemblGRCr8
mRatBN7.21496,991,853 - 97,004,732 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1496,991,859 - 97,005,267 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx14101,325,100 - 101,337,974 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.014102,567,399 - 102,580,273 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01499,039,002 - 99,051,876 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.014107,767,392 - 107,780,270 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl14107,767,392 - 107,780,270 (+)Ensemblrn6Rnor6.0
Rnor_5.014107,843,411 - 107,856,260 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.414103,675,110 - 103,687,893 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1495,973,133 - 95,985,983 (+)NCBICelera
RGSC_v3.114103,694,320 - 103,707,104 (+)NCBI
Cytogenetic Map14q22NCBI
CCT4
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38261,868,085 - 61,888,671 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl261,868,085 - 61,888,696 (-)Ensemblhg38GRCh38
GRCh37262,095,220 - 62,115,806 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36261,948,766 - 61,969,295 (-)NCBIBuild 36Build 36hg18NCBI36
Build 34262,006,913 - 62,027,442NCBI
Celera261,940,173 - 61,960,736 (-)NCBICelera
Cytogenetic Map2p15NCBI
HuRef261,835,217 - 61,855,722 (-)NCBIHuRef
CHM1_1262,025,224 - 62,045,751 (-)NCBICHM1_1
T2T-CHM13v2.0261,874,246 - 61,894,829 (-)NCBIT2T-CHM13v2.0
Cct4
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391122,940,593 - 22,953,336 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1122,940,519 - 22,953,780 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm381122,990,593 - 23,003,336 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1122,990,519 - 23,003,780 (+)Ensemblmm10GRCm38
MGSCv371122,890,593 - 22,903,336 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361122,890,593 - 22,903,336 (+)NCBIMGSCv36mm8
Celera1125,126,226 - 25,138,969 (+)NCBICelera
Cytogenetic Map11A3.2NCBI
cM Map1114.25NCBI
Cct4
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542422,088,949 - 22,108,514 (+)Ensembl
ChiLan1.0NW_00495542422,088,949 - 22,108,514 (+)NCBIChiLan1.0ChiLan1.0
CCT4
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21264,495,636 - 64,516,010 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12A64,499,652 - 64,519,655 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02A61,950,477 - 61,970,783 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12A63,084,090 - 63,104,530 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2A63,084,090 - 63,105,216 (-)EnsemblpanPan2panpan1.1
CCT4
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11061,859,148 - 61,874,030 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1061,859,245 - 61,874,389 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha1061,748,927 - 61,763,778 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.01062,867,889 - 62,882,584 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1062,867,244 - 62,882,587 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11062,551,782 - 62,566,434 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01062,855,534 - 62,870,428 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01063,151,020 - 63,165,931 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Cct4
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440629221,330,016 - 21,346,300 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364917,224,692 - 7,241,358 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049364917,224,989 - 7,241,348 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CCT4
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl379,924,507 - 79,946,207 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1379,924,338 - 79,941,926 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2383,760,065 - 83,777,463 (+)NCBISscrofa10.2Sscrofa10.2susScr3
CCT4
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11445,086,932 - 45,106,922 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1445,086,920 - 45,111,271 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366604566,727,959 - 66,748,110 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Cct4
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462483346,076 - 62,665 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462483346,071 - 62,665 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Cct4
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v11193,889,264 - 93,901,736 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Cct4
124 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:28
Count of miRNA genes:25
Interacting mature miRNAs:26
Transcripts:ENSRNOT00000012847
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
634328Hc5Hypercalciuria QTL 52.3urine calcium amount (VT:0002985)urine calcium excretion rate (CMO:0000763)1462398852107398852Rat
9590294Uminl4Urine mineral level QTL 45.660.001urine mineral amount (VT:0015086)urine electrolyte level (CMO:0000593)1459848686104848686Rat
2317879Alcrsp27Alcohol response QTL 273.30.63response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)1460854936105854936Rat
1641900Alcrsp11Alcohol response QTL 11alcohol metabolism trait (VT:0015089)blood ethanol level (CMO:0000535)1474255551109089856Rat
2300197Scl59Serum cholesterol level QTL 59blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)1477914838104348525Rat
9589034Epfw11Epididymal fat weight QTL 1160.001epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)1459848686104848686Rat
631523Pia13Pristane induced arthritis QTL 133.3joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1433424686102238540Rat
1582259Gluco23Glucose level QTL 233.10.0008blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)1474255551109089856Rat

Markers in Region
BE118339  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21497,001,371 - 97,001,556 (+)MAPPERmRatBN7.2
Rnor_6.014107,776,910 - 107,777,094NCBIRnor6.0
Rnor_5.014107,852,903 - 107,853,087UniSTSRnor5.0
RGSC_v3.414103,684,664 - 103,684,848UniSTSRGSC3.4
Celera1495,982,642 - 95,982,826UniSTS
RH 3.4 Map14766.5UniSTS
Cytogenetic Map14q22UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 165 91 90 59 92 59 6 356 192 11 144 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000012847   ⟹   ENSRNOP00000012847
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl14101,192,772 - 101,205,770 (+)Ensembl
mRatBN7.2 Ensembl1496,991,859 - 97,005,267 (+)Ensembl
Rnor_6.0 Ensembl14107,767,392 - 107,780,270 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000109669   ⟹   ENSRNOP00000078161
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl14101,192,772 - 101,205,770 (+)Ensembl
mRatBN7.2 Ensembl1496,991,859 - 97,005,267 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000116685   ⟹   ENSRNOP00000086401
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1496,993,448 - 97,005,267 (+)Ensembl
RefSeq Acc Id: NM_182814   ⟹   NP_877966
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr814101,193,057 - 101,205,935 (+)NCBI
mRatBN7.21496,991,853 - 97,004,732 (+)NCBI
Rnor_6.014107,767,392 - 107,780,270 (+)NCBI
Rnor_5.014107,843,411 - 107,856,260 (+)NCBI
RGSC_v3.414103,675,110 - 103,687,893 (+)RGD
Celera1495,973,133 - 95,985,983 (+)RGD
Sequence:
Protein Sequences
Protein RefSeqs NP_877966 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAH79283 (Get FASTA)   NCBI Sequence Viewer  
  AAP46161 (Get FASTA)   NCBI Sequence Viewer  
  EDL97980 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000012847
  ENSRNOP00000012847.3
GenBank Protein Q7TPB1 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_877966   ⟸   NM_182814
- UniProtKB: Q7TPB1 (UniProtKB/Swiss-Prot),   A6JQ63 (UniProtKB/TrEMBL),   A0A8I5YC75 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000012847   ⟸   ENSRNOT00000012847
Ensembl Acc Id: ENSRNOP00000078161   ⟸   ENSRNOT00000109669
Ensembl Acc Id: ENSRNOP00000086401   ⟸   ENSRNOT00000116685

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q7TPB1-F1-model_v2 AlphaFold Q7TPB1 1-539 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13699519
Promoter ID:EPDNEW_R10043
Type:initiation region
Name:Cct4_1
Description:chaperonin containing TCP1 subunit 4
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.014107,767,398 - 107,767,458EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:727937 AgrOrtholog
BioCyc Gene G2FUF-14788 BioCyc
Ensembl Genes ENSRNOG00000009642 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000012847 ENTREZGENE
  ENSRNOT00000012847.4 UniProtKB/Swiss-Prot
Gene3D-CATH 1.10.560.10 UniProtKB/Swiss-Prot
  3.30.260.10 UniProtKB/Swiss-Prot
  3.50.7.10 UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:7134210 IMAGE-MGC_LOAD
InterPro Chap_CCT_delta UniProtKB/Swiss-Prot
  Chaperone_TCP-1 UniProtKB/Swiss-Prot
  Chaperonin_TCP-1_CS UniProtKB/Swiss-Prot
  Cpn60/TCP-1 UniProtKB/Swiss-Prot
  GroEL-like_apical_dom_sf UniProtKB/Swiss-Prot
  GROEL-like_equatorial_sf UniProtKB/Swiss-Prot
  TCP-1-like_intermed_sf UniProtKB/Swiss-Prot
  TCP-1_chaperonin UniProtKB/Swiss-Prot
  thermosome_alpha UniProtKB/Swiss-Prot
KEGG Report rno:29374 UniProtKB/Swiss-Prot
MGC_CLONE MGC:94410 IMAGE-MGC_LOAD
NCBI Gene 29374 ENTREZGENE
PANTHER PTHR11353 UniProtKB/Swiss-Prot
Pfam Cpn60_TCP1 UniProtKB/Swiss-Prot
PhenoGen Cct4 PhenoGen
PRINTS TCOMPLEXTCP1 UniProtKB/Swiss-Prot
PROSITE TCP1_1 UniProtKB/Swiss-Prot
  TCP1_2 UniProtKB/Swiss-Prot
  TCP1_3 UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000009642 RatGTEx
Superfamily-SCOP SSF48592 UniProtKB/Swiss-Prot
  SSF52029 UniProtKB/Swiss-Prot
  SSF54849 UniProtKB/Swiss-Prot
UniProt A0A8I5YC75 ENTREZGENE, UniProtKB/TrEMBL
  A6JQ63 ENTREZGENE, UniProtKB/TrEMBL
  Q7TPB1 ENTREZGENE, UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-01-13 Cct4  chaperonin containing TCP1 subunit 4  Cct4  chaperonin containing Tcp1, subunit 4 (delta)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-09-29 Cct4  chaperonin containing Tcp1, subunit 4 (delta)  Cct4  chaperonin subunit 4 (delta)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2004-12-14 Cct4  chaperonin subunit 4 (delta)      Symbol and Name status set to approved 1299863 APPROVED

RGD Curation Notes
Note Type Note Reference
gene_mutations_overexpression 1349G>A mutation causes hereditary sensory neuropathy 1299607