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Gene: Amotl2 (angiomotin like 2) Rattus norvegicus

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Symbol:

Amotl2

Name:

angiomotin like 2

RGD ID:

70977

Description:

Predicted to enable actin filament binding activity and identical protein binding activity. Predicted to be involved in several processes, including endothelial cell morphogenesis; establishment of cell polarity involved in ameboidal cell migration; and hippo signaling. Predicted to be located in several cellular components, including apical plasma membrane; cell junction; and podosome. Predicted to be active in bicellular tight junction; cytoplasmic vesicle; and plasma membrane. Orthologous to human AMOTL2 (angiomotin like 2); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

angiomotin-like protein 2; Lccp; Leman coiled-coil protein

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	AMOTL2 (angiomotin like 2)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther
Mus musculus (house mouse):	Amotl2 (angiomotin-like 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Amotl2 (angiomotin like 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	AMOTL2 (angiomotin like 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	AMOTL2 (angiomotin like 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Amotl2 (angiomotin like 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	AMOTL2 (angiomotin like 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	AMOTL2 (angiomotin like 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Amotl2 (angiomotin like 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus rattus (black rat):	Amotl2 (angiomotin like 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Other homologs ²
Homo sapiens (human):	MARK2 (microtubule affinity regulating kinase 2)	HGNC	OMA
Alliance orthologs ³
Homo sapiens (human):	AMOTL2 (angiomotin like 2)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Amotl2 (angiomotin-like 2)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	amotl2b (angiomotin like 2b)	Alliance	DIOPT (Ensembl Compara\|OrthoFinder\|PANTHER\|PhylomeDB)
Danio rerio (zebrafish):	amotl2a (angiomotin like 2a)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Caenorhabditis elegans (roundworm):	F59C12.3	Alliance	DIOPT (Ensembl Compara\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	amotl2	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	8	112,182,060 - 112,198,032 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	8	112,181,863 - 112,198,030 (+)	Ensembl				GRCr8
mRatBN7.2	8	103,303,368 - 103,319,161 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	8	103,302,992 - 103,318,910 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	8	108,967,179 - 108,982,616 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	8	107,166,330 - 107,181,767 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	8	105,009,012 - 105,024,449 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	8	111,210,261 - 111,226,217 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	8	111,209,908 - 111,226,226 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	8	110,603,968 - 110,619,845 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	8	107,694,405 - 107,709,841 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	8	102,684,968 - 102,700,275 (+)	NCBI		Celera
RGSC_v3.1	8	107,716,856 - 107,724,559 (+)	NCBI
Cytogenetic Map	8	q32	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

17beta-estradiol (EXP,ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

3,3',5,5'-tetrabromobisphenol A (ISO)

3-isobutyl-1-methyl-7H-xanthine (ISO)

4,4'-sulfonyldiphenol (ISO)

4-hydroxyphenyl retinamide (ISO)

6-propyl-2-thiouracil (EXP)

acrolein (ISO)

acrylamide (EXP,ISO)

aflatoxin B1 (ISO)

alpha-pinene (ISO)

alpha-Zearalanol (EXP)

amitrole (EXP)

ammonium chloride (EXP)

amphetamine (EXP)

aristolochic acid A (ISO)

arsenite(3-) (ISO)

benzo[a]pyrene (ISO)

benzo[e]pyrene (ISO)

beta-lapachone (ISO)

bexarotene (ISO)

bisphenol A (EXP,ISO)

bisphenol F (ISO)

cadmium atom (ISO)

cadmium dichloride (ISO)

caffeine (ISO)

carbamazepine (ISO)

carbon nanotube (ISO)

CGP 52608 (ISO)

cisplatin (ISO)

copper atom (ISO)

copper(0) (ISO)

copper(II) chloride (ISO)

copper(II) sulfate (ISO)

coumarin (ISO)

coumestrol (ISO)

crocidolite asbestos (ISO)

Cuprizon (EXP)

cyclosporin A (ISO)

dexamethasone (ISO)

dibutyl phthalate (ISO)

diclofenac (ISO)

diuron (EXP)

dorsomorphin (ISO)

doxorubicin (ISO)

endosulfan (EXP)

Enterolactone (ISO)

fenamidone (ISO)

FR900359 (ISO)

fulvestrant (ISO)

gentamycin (EXP)

hydrogen peroxide (ISO)

indometacin (ISO)

leflunomide (ISO)

lipopolysaccharide (EXP,ISO)

menadione (ISO)

methapyrilene (ISO)

methylmercury chloride (ISO)

methylparaben (ISO)

N-methyl-4-phenylpyridinium (ISO)

N1'-[2-[[5-[(dimethylamino)methyl]-2-furanyl]methylthio]ethyl]-N1-methyl-2-nitroethene-1,1-diamine (EXP)

ochratoxin A (ISO)

okadaic acid (ISO)

organophosphorus compound (EXP)

orphenadrine (EXP)

oxaliplatin (EXP)

ozone (ISO)

paracetamol (ISO)

paraquat (EXP)

perfluorooctanoic acid (EXP,ISO)

phenylmercury acetate (ISO)

pioglitazone (ISO)

pirinixic acid (ISO)

pregnenolone 16alpha-carbonitrile (EXP)

quercetin (ISO)

raloxifene (ISO)

ranitidine (EXP)

Rutecarpine (ISO)

S-(1,2-dichlorovinyl)-L-cysteine (ISO)

SB 431542 (ISO)

silicon dioxide (ISO)

silver atom (ISO)

silver(0) (ISO)

sodium arsenite (ISO)

sunitinib (ISO)

tert-butyl hydroperoxide (ISO)

tetrachloromethane (ISO)

thioacetamide (EXP)

thiram (ISO)

topotecan (EXP)

triptonide (ISO)

troglitazone (ISO)

trovafloxacin (ISO)

valproic acid (ISO)

vinclozolin (EXP)

vorinostat (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

actin cytoskeleton organization (IBA)

angiogenesis (IBA)

endothelial cell morphogenesis (ISO,ISS)

establishment of cell polarity involved in ameboidal cell migration (IBA)

hippo signaling (IBA,ISO)

negative regulation of transcription by RNA polymerase II (ISO,ISS)

positive regulation of protein localization (IEA,ISO,ISS)

regulation of cell migration (IBA)

Wnt signaling pathway (IEA)

Cellular Component

anchoring junction (IEA)

apical plasma membrane (ISO)

bicellular tight junction (IBA,ISO)

cell junction (ISO,ISS)

cytoplasm (IEA,ISO,ISS)

cytoplasmic vesicle (IBA,ISO)

plasma membrane (IBA)

podosome (IEA,ISO,ISS)

recycling endosome (IEA)

Molecular Function

actin filament binding (ISO,ISS)

identical protein binding (ISO)

protein binding (ISO)

protein-containing complex binding (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Angiomotin belongs to a novel protein family with conserved coiled-coil and PDZ binding domains.	Bratt A, etal., Gene 2002 Sep 18;298(1):69-77.
2.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3.	Rat ISS GO annotations from MGI mouse gene data--August 2006	MGD data from the GO Consortium
4.	Electronic Transfer of LocusLink and RefSeq Data	NCBI rat LocusLink and RefSeq merged data July 26, 2002
5.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:16019084	PMID:17397395	PMID:21205866	PMID:39027975

Genomics

Comparative Map Data

Amotl2
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	8	112,182,060 - 112,198,032 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	8	112,181,863 - 112,198,030 (+)	Ensembl				GRCr8
mRatBN7.2	8	103,303,368 - 103,319,161 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	8	103,302,992 - 103,318,910 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	8	108,967,179 - 108,982,616 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	8	107,166,330 - 107,181,767 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	8	105,009,012 - 105,024,449 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	8	111,210,261 - 111,226,217 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	8	111,209,908 - 111,226,226 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	8	110,603,968 - 110,619,845 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	8	107,694,405 - 107,709,841 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	8	102,684,968 - 102,700,275 (+)	NCBI		Celera
RGSC_v3.1	8	107,716,856 - 107,724,559 (+)	NCBI
Cytogenetic Map	8	q32	NCBI

AMOTL2
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	3	134,355,345 - 134,375,417 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	3	134,355,347 - 134,375,479 (-)	Ensembl			hg38	GRCh38
GRCh37	3	134,074,187 - 134,094,259 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	3	135,556,880 - 135,576,096 (-)	NCBI	Build 36	Build 36	hg18	NCBI36
Build 34	3	135,556,887 - 135,576,104	NCBI
Celera	3	132,500,465 - 132,519,692 (-)	NCBI		Celera
Cytogenetic Map	3	q22.2	NCBI
HuRef	3	131,452,026 - 131,472,100 (-)	NCBI		HuRef
CHM1_1	3	134,038,283 - 134,058,339 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	3	137,100,500 - 137,120,572 (-)	NCBI		T2T-CHM13v2.0

Amotl2
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	9	102,594,290 - 102,610,616 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	9	102,593,871 - 102,610,617 (+)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	9	102,717,091 - 102,733,418 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	9	102,716,672 - 102,733,418 (+)	Ensembl			mm10	GRCm38
MGSCv37	9	102,620,134 - 102,635,747 (+)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	9	102,580,684 - 102,591,563 (+)	NCBI		MGSCv36	mm8
Celera	9	102,259,128 - 102,274,693 (+)	NCBI		Celera
Cytogenetic Map	9	F1	NCBI
cM Map	9	54.71	NCBI

Amotl2
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955501	4,192,063 - 4,211,562 (+)	Ensembl
ChiLan1.0	NW_004955501	4,192,339 - 4,209,150 (+)	NCBI	ChiLan1.0	ChiLan1.0

AMOTL2
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	2	132,281,821 - 132,299,679 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	3	132,286,549 - 132,305,216 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	3	131,402,375 - 131,421,030 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	3	138,874,302 - 138,892,913 (-)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	3	138,874,309 - 138,892,913 (-)	Ensembl			panPan2	panpan1.1

AMOTL2
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	23	31,147,420 - 31,165,120 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	23	31,148,609 - 31,162,369 (-)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	23	31,125,977 - 31,143,625 (-)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	23	31,663,168 - 31,680,819 (-)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	23	31,663,173 - 31,680,757 (-)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	23	31,360,413 - 31,378,048 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	23	31,418,995 - 31,436,602 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	23	31,666,646 - 31,684,285 (-)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Amotl2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405602	70,694,281 - 70,711,193 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936529	7,454,763 - 7,471,718 (-)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936529	7,454,778 - 7,471,660 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

AMOTL2
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	13	75,490,942 - 75,509,420 (-)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	13	75,490,936 - 75,507,360 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	13	83,024,424 - 83,038,681 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

AMOTL2
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	15	56,002,474 - 56,021,838 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	15	56,003,236 - 56,022,123 (+)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM
Vero_WHO_p1.0	NW_023666041	28,986,214 - 29,005,590 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Amotl2
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624730	10,695,138 - 10,713,808 (-)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
HetGla 1.0	NW_004624730	10,695,648 - 10,713,188 (-)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Amotl2
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	8	94,020,427 - 94,036,323 (+)	NCBI		Rrattus_CSIRO_v1

Variants

Variants in Amotl2
117 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	510
Count of miRNA genes:	208
Interacting mature miRNAs:	291
Transcripts:	ENSRNOT00000011347
Prediction methods:	Microtar, Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
2303171	Bp331	Blood pressure QTL 331	5.57	0.005	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	8	105462581	132782436	Rat
1549909	Stresp11	Stress response QTL 11	6.83	0.0019	stress-related behavior trait (VT:0010451)	number of approaches toward negative stimulus before onset of defensive burying response (CMO:0001960)	8	82352698	127352698	Rat
631210	Bw3	Body weight QTL3	5.9		mesenteric fat pad mass (VT:0010427)	mesenteric fat pad weight to body weight ratio (CMO:0000654)	8	61019838	121662124	Rat
1554321	Bmd3	Bone mineral density QTL 3	7.9	0.0001	femur mineral mass (VT:0010011)	volumetric bone mineral density (CMO:0001553)	8	49849908	118871671	Rat
9590292	Uminl3	Urine mineral level QTL 3	3.62	0.001	urine mineral amount (VT:0015086)	urine electrolyte level (CMO:0000593)	8	80768445	125768445	Rat
8694446	Bw170	Body weight QTL 170	12.07	0.001	retroperitoneal fat pad mass (VT:0010430)	retroperitoneal fat pad weight to body weight ratio (CMO:0000635)	8	80768445	125768445	Rat
631650	Stl6	Serum triglyceride level QTL 6	4	0.0019	blood triglyceride amount (VT:0002644)	plasma triglyceride level (CMO:0000548)	8	70041301	121080908	Rat
1581557	Eae16	Experimental allergic encephalomyelitis QTL 16	3.8		nervous system integrity trait (VT:0010566)	experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)	8	68690349	119799881	Rat
10450865	Bw175	Body weight QTL 175	4.1		total fat pad mass (VT:0015008)	adipose tissue molecular composition measurement (CMO:0000484)	8	84192326	129192326	Rat
738011	Anxrr9	Anxiety related response QTL 9	6.1		exploratory behavior trait (VT:0010471)	number of entries into a discrete space in an experimental apparatus (CMO:0000960)	8	102413464	132782436	Rat
724539	Cm19	Cardiac mass QTL 19	2.6		heart mass (VT:0007028)	calculated heart weight (CMO:0000073)	8	103375781	129871912	Rat
8693654	Alc32	Alcohol consumption QTL 32	2	0.755	drinking behavior trait (VT:0001422)	calculated ethanol drink intake rate (CMO:0001615)	8	97492344	116428905	Rat
70197	BpQTLcluster8	Blood pressure QTL cluster 8	3.482		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	8	55428333	127966348	Rat
2316950	Scl66	Serum cholesterol level QTL 66	4.1		blood cholesterol amount (VT:0000180)	plasma total cholesterol level (CMO:0000585)	8	39106363	114525825	Rat
634332	Pia18	Pristane induced arthritis QTL 18	4		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	8	84192326	132782436	Rat
2300181	Bmd55	Bone mineral density QTL 55	5.7	0.0001	femur mineral mass (VT:0010011)	volumetric bone mineral density (CMO:0001553)	8	85348065	130348065	Rat
1300171	Bp184	Blood pressure QTL 184	3.66		arterial blood pressure trait (VT:2000000)	blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)	8	79394435	132782436	Rat
631217	Activ1	Activity QTL 1	15.9		voluntary movement trait (VT:0003491)	number of photobeam interruptions in an experimental apparatus (CMO:0001517)	8	111249511	117802327	Rat
2313400	Anxrr25	Anxiety related response QTL 25			aggression-related behavior trait (VT:0015014)	tameness/aggressiveness composite score (CMO:0002136)	8	98145073	122898010	Rat
8694200	Abfw4	Abdominal fat weight QTL 4	9.07	0.001	visceral adipose mass (VT:0010063)	abdominal fat pad weight to body weight ratio (CMO:0000095)	8	80768445	125768445	Rat
8694392	Bw161	Body weight QTL 161	8.06	0.001	body lean mass (VT:0010483)	lean tissue morphological measurement (CMO:0002184)	8	80768445	125768445	Rat
61437	Cia6	Collagen induced arthritis QTL 6			joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	8	91340911	131690273	Rat

Markers in Region

SGC32004

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	8	103,319,009 - 103,319,135 (+)	MAPPER	mRatBN7.2
Rnor_6.0	8	111,226,066 - 111,226,191	NCBI	Rnor6.0
Rnor_5.0	8	110,619,694 - 110,619,819	UniSTS	Rnor5.0
RGSC_v3.4	8	107,709,695 - 107,709,820	UniSTS	RGSC3.4
Celera	8	102,700,129 - 102,700,254	UniSTS
Cytogenetic Map	8	q32	UniSTS

RH143423

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	8	103,305,467 - 103,305,607 (+)	MAPPER	mRatBN7.2
Rnor_6.0	8	111,212,524 - 111,212,663	NCBI	Rnor6.0
Rnor_5.0	8	110,606,163 - 110,606,302	UniSTS	Rnor5.0
RGSC_v3.4	8	107,696,118 - 107,696,257	UniSTS	RGSC3.4
Celera	8	102,686,681 - 102,686,820	UniSTS
Cytogenetic Map	8	q32	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
16	12	67	162	91	90	59	85	59	6	349	185	11	141	81	92	31	17	17

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_031717	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006243680	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039082102	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AF175969	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473954	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000008	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000011347 ⟹ ENSRNOP00000011347

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	8	103,303,744 - 103,318,910 (+)	Ensembl
Rnor_6.0 Ensembl	8	111,210,811 - 111,226,193 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000090221 ⟹ ENSRNOP00000075540

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	8	112,181,863 - 112,198,030 (+)	Ensembl
mRatBN7.2 Ensembl	8	103,302,992 - 103,318,910 (+)	Ensembl
Rnor_6.0 Ensembl	8	111,209,908 - 111,226,226 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000094404 ⟹ ENSRNOP00000093935

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	8	112,182,052 - 112,198,030 (+)	Ensembl
mRatBN7.2 Ensembl	8	103,303,218 - 103,318,910 (+)	Ensembl

RefSeq Acc Id:

NM_031717 ⟹ NP_113905

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	8	112,182,626 - 112,198,027 (+)	NCBI
mRatBN7.2	8	103,303,755 - 103,319,156 (+)	NCBI
Rnor_6.0	8	111,210,811 - 111,226,212 (+)	NCBI
Rnor_5.0	8	110,603,968 - 110,619,845 (+)	NCBI
RGSC_v3.4	8	107,694,405 - 107,709,841 (+)	RGD
Celera	8	102,684,968 - 102,700,275 (+)	RGD

Sequence:

show sequence

CGGCGCCACCGACGAGTGCGCACCTCCGTTGCCGACCGTACCTAAGCCGAACCCGGTCTGCGTG
CGCCGGCAGCCGCGGGCCGCAGCGGTGCTCTGAGACCAGGTGCCTGCTGGCCATTGTCTAGGCA
GGTGTGTGCAAGCCAGAGAAGCATGAGGACACTGGAAGACTCCTCAGGGACAGTCCTGCACCGC
CTCATCCAGGAGCAGCTGCGCTACGGCAACCTGACAGAGACTCGCACTCTGTTGGCCATCCAGC
AGCAGGCCCTGCGGGGTGGGGCTGGAGCTGGGGGCACAGGGAGCCCCCAGGCCTCCCTGGAGAT
CGGAGCACCCGAGGACAGTCAGGTGCTACAGCAGGCCACCAGGCAGGAGCCCCAGGGCCAGGAG
CATCAGGGTGGAGAGACCCACCTGGCAGAGAACAGGCTGTACCGACTCTGCCCACAGCCCAGCA
AGGGAGAAGAGCTGCCCACCTATGAGGAAGCCAAAGCCCATTCGCAGTACTATGCAGCGCAGCA
GGCAGGCTCCCGGCTGCATGGTGGGGACCGGGATCCTAGAGGGGCCTCAGGAGGCAGCCGACGT
CAGGATGAGGCTCTTCGAGAGTTGAGGCACGGCCATGTGCGCTCCTTGAGTGAACGACTTCTGC
AGCTGTCCCTGGAAAGAAATGGTGCCCGGGTCCCCAGCCACATGAGCTCTTCCCACAGTTTCCC
TCAGCTGGCCCGCAGCCAGCAAGGTCCCCAGCCCCGAGGACCCCCAGCTGAGGGCCCGGAGCCC
CGTGGGCCACCACCTCAGTACCCACACGCTGTAATGGCTCAGGAGACTGCGGCTGTCAATGACC
CAAGATACCGTCCGAGAAGCAGCCCACACTTCCAGCATGCTGAAGTCAGGATCCTGCAGGCACA
GGTACCACCGGTTTTCCTCCAGCAGCAACAGTACCAGTACCTGCAGCAACCCCAGGAGCACTCC
CCACCCCTCCATCCAGCCGCTCTAGGCCATGGTCCCCCAAGTTCCTTCAGTCCACCTGCCCTGG
AGGGACCACCCGGTGCCCAGGCCACTTCGGGCAGTGCCCACCTGGCCCAGATGGAGAGCGTGCT
GAGGGAGAACGCCAGGCTGCAGAGGGACAATGAGCGGTTGCAGAGAGAGCTGGAGAGCACTTCA
GAGAAGGCCAGCTGCATAGAAAAGCTGGAAAATGAAATCCAGCGGCTCTCAGAGGCCCATGAGA
GCCTGATGAGGACCTCGTCCAAGCGTGAGGCCCTGGAGAAGACCATGAGGAACAAGATGGACAG
TGAAATGAGACGGTTACAGGACTTTAACCGAGACCTTAGAGAGAGATTGGAGTCCGCAAACCGC
CACCTGGCAAGCAAGACCCAGGAAGCCCAGGCGGGCAGTCAGGACATGGTGGCTAAACTGCTTG
CTCAGAGCTATGAGCAGCAACAGGAGCAAGAGAAGCTGGAGCGGGAGATGGCGCTGCTGCGTGG
TGCCATCGAGGACCAGAGGCGACGGGCTGAACTGCTGGAGCAGGCTCTGGGCAACGCGCAGAGC
CGCGCCGCTCGAGCGGAGGAGGAGCTACGCAAGAAGCAGGCCTACGTGGAGAAGGTGGAGCGGC
TGCAGCAGGCGCTGGGACAGTTGCAGGCTGCTTGTGAAAAGCGGGAGCAGCTGGAGCTGCGTCT
GCGCACGCGCCTGGAGCAGGAACTCAAAGCCTTGCGCGCGCAGCAGAGGCAGACAGGCACCCTC
ACAGGTGGTGGCGGTAGCCACACTGGGTCCACGGAGCTCAGTGCCCTGCGACTGTCAGAACAGC
TTCGGGAGAAGGAGGAACAGATACTGGCTCTAGAGGCGGACATGACCAAGTGGGAACAAAAGTA
TTTGGAGGAACGGGCCATGAGGCAGTTTGCCATGGATGCGGCTGCCACTGCGGCTGCCCAGCGA
GACACCACTCTCATCAGACACTCCCCCCAGCCCTCGCCCAGCAGCAGTTTCAACGAAGGCCTGC
TGGCAGGCAACCACAGGCACCAGGAGATGGAGAGCAGGTTGAAGGTGCTCCATGCCCAGATCCT
AGAGAAAGACGCAGTGATCAAGGTCCTTCAACAGCGTTCCAGGAAAGACCCTGGCAAGGCTACC
CAGGGCACCCTACGGCCCGCCAAGTCGGTGCCGTCCATCTTTGCAGCTGCAGTGGGGACTCAGG
GCTGGCAAGGGTTCTCAACCAGCGAGCGACAAACTGATGCACCTGCCCGACAGACAGTAGACCG
TGGACCAGCAGAAGAGCCCCCGGCCACACCTCCTCTCCCTGCCCACACCAAACATGGCAGCAGA
GACGGGAGCACCCAAACTGATGGCCCTGCAGACAGCACCTCTGCCTGCTTGGCCTCAGAACCCG
ACAGCCTCCTGGGGTGCAACGGTAGCCAGAGGACAACCTCTCTGGACTCTATAGCTGCAACCAG
AGTCCAGGATCTGTCAGACATGGTGGAAATACTGATCTGAAGGAAGGAGGCCTTGGGGACCCTG
AAGCCTGGCTCCCCCATGGCATTCCAGCAATTGTCTTCAAATGCTGCACCTCACTTCCTCCAAC
CAGCAATGGTTTGGTGCAGGAGCTCAGAGAGGAGCACTCCAGGGGAGCCAGAAAAGGCTGCACC
CCCAGAAGACTGCTTTTTTTTGACCTATATTTCTCCCACGACAATGAGGAAGGAAGAGGTCTGT
TGCTGGAGCAGGAAGGGGCTGAGCCCCCTCCGTCCTGCCAGTTTGTATTTGGGCATGAAGGGAA
AGGAGACTGGATTCTGATTCCCAAGAATGGCTGGACACCAGCCAAATGGTCTGCAGGGATAATC
AGGCCAAACCATGGTGTTCTGTGGCTAAGCATGGCCCCAGCCAGCCCTAACTGCTCTCAGTCCC
TCACTGCCTTCTTCAGATCACTAAGACTTGAATCTTTTGGGGAACCATTGGGAGTGTGAGCCTT
TCGGGAGCCACCAGCATGTCCCCTTGCTTGGAGTAGGTTAGAGGCCATTTGAGAGGCCCGCAGA
ACAGTGTGTTTTGTATATAATTCTCTTTCCTTGGGAACAGAAGACTAAGCATGCTGGTTCAGAG
TCTCCTTCCAGAGCTGTGCTGCCTGCCCCTGCTTGCCACAGTTCTTGAAACATTTGACAGGTCT
ACCAGATGTCCCTCTGCCTCCAGTTCTTGGCGGTGTTTTTTTGATACTGGTTGCCTTTCCTCTG
TTTTAAACCCCTGTGTTCAATGCCCGTGGGATTCTTGTCACCAGCCTTTGTTGTGAACGGCTCC
ACCGCTCCTACCCCTGGGACATCCTGTCAGTTTGGTTATAAACTGAGCCAGATGCGATGAGCCA
CAACAAGCGGATATCTGTCATACCCAGCCCCAGGTTCTCTTTGAAGAAACTGGAGACGTTGTTC
TCATAAACGTGTTCGTTCCCACCAGCAGGGACTGGGAGAGGGAGCTATGCTGTTAAAAGTAATC
GGTGAACTTAAAGAAAAGTCCCCACTAGGTGCCCCCATCACAGAATGGCACCCAAGAGGCTGGC
TCCTCGAGCTTTGGTGCCCCAGCCCTGAAGCAGGGCCAGCTACTCGGAATTAGGCAGCCTACCA
GCAGCAGTGACTTTAACTTCTGGTCTTAAAGTAACCCCCATTCAGCTGAAAAAGCGATTGGTGG
ATTGCAGATCTGTTGTGTTTTCTCTTGTTGTTTTGTTCGTTTTTTCTCTCATTGTTTGAAGTTC
TGTCTGTTGTTCCATTCCCATGGTTCTCCGTGTTTCCTTTTTAAACATTTGCATTTGCTGGGCA
ATTGCGTATTTTTTTAATTCCCCTTTTCCCCTGTGTAAAGCTGAGAAATACATCTGGTTCATGT
GCGTTGTTTACAAAGATAAAAGTTTAAAAAAAAAACAAAAAAAAAGGAGGGAAAAACAAAAAAT
ATCGTGAAAGAAAAAAAACAACTTAATATATTTTGGATTAATATTTGGTATTTCTTTTAAAATA
TTTTTTTTGTGCTGTGAACGTTTTCTGCCAAAGACCATGACGTGTGTCTGTGTGTTTAAGTTAT
CATGAATATTTAAGGTGCAAACATGGCTGTTTTGTCACGCCACTCTGTACCAGGATTGCCGAAG
CATTCCACTGGGTATGACAGTATTTTAATAAAAAAAAAAGCTTAT

hide sequence

RefSeq Acc Id:

XM_006243680 ⟹ XP_006243742

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	8	112,182,060 - 112,198,032 (+)	NCBI
mRatBN7.2	8	103,303,368 - 103,319,161 (+)	NCBI
Rnor_6.0	8	111,210,261 - 111,226,217 (+)	NCBI
Rnor_5.0	8	110,603,968 - 110,619,845 (+)	NCBI

Sequence:

show sequence

GGGCAGCTGCGGGCCGAAGCATCGGTTGGTTCGCCTGCAACACGGCCCAAGCTGGGCGGATGTA
AAGTGCTTTGCAGTCCTCCCGCCATCTCCAAAAAGCCACAGACCCCTCTTGCAGCCACCACCGG
GCGTTCGAGGCTTATCCCTGGAAGTCGTCCCTCGGTGCATGTAAGGATGACGGGTGCTCTGAGA
CCAGGTGCCTGCTGGCCATTGTCTAGGCAGGTGTGTGCAAGCCAGAGAAGCATGAGGACACTGG
AAGACTCCTCAGGGACAGTCCTGCACCGCCTCATCCAGGAGCAGCTGCGCTACGGCAACCTGAC
AGAGACTCGCACTCTGTTGGCCATCCAGCAGCAGGCCCTGCGGGGTGGGGCTGGAGCTGGGGGC
ACAGGGAGCCCCCAGGCCTCCCTGGAGATCGGAGCACCCGAGGACAGTCAGGTGCTACAGCAGG
CCACCAGGCAGGAGCCCCAGGGCCAGGAGCATCAGGGTGGAGAGACCCACCTGGCAGAGAACAG
GCTGTACCGACTCTGCCCACAGCCCAGCAAGGGAGAAGAGCTGCCCACCTATGAGGAAGCCAAA
GCCCATTCGCAGTACTATGCAGCGCAGCAGGCAGGCTCCCGGCTGCATGGTGGGGACCGGGATC
CTAGAGGGGCCTCAGGAGGCAGCCGACGTCAGGATGAGGCTCTTCGAGAGTTGAGGCACGGCCA
TGTGCGCTCCTTGAGTGAACGACTTCTGCAGCTGTCCCTGGAAAGAAATGGTGCCCGGGTCCCC
AGCCACATGAGCTCTTCCCACAGTTTCCCTCAGCTGGCCCGCAGCCAGCAAGGTCCCCAGCCCC
GAGGACCCCCAGCTGAGGGCCCGGAGCCCCGTGGGCCACCACCTCAGTACCCACACGCTGTAAT
GGCTCAGGAGACTGCGGCTGTCAATGACCCAAGATACCGTCCGAGAAGCAGCCCACACTTCCAG
CATGCTGAAGTCAGGATCCTGCAGGCACAGGTACCACCGGTTTTCCTCCAGCAGCAACAGTACC
AGTACCTGCAGCAACCCCAGGAGCACTCCCCACCCCTCCATCCAGCCGCTCTAGGCCATGGTCC
CCCAAGTTCCTTCAGTCCACCTGCCCTGGAGGGACCACCCGGTGCCCAGGCCACTTCGGGCAGT
GCCCACCTGGCCCAGATGGAGAGCGTGCTGAGGGAGAACGCCAGGCTGCAGAGGGACAATGAGC
GGTTGCAGAGAGAGCTGGAGAGCACTTCAGAGAAGGCCAGCTGCATAGAAAAGCTGGAAAATGA
AATCCAGCGGCTCTCAGAGGCCCATGAGAGCCTGATGAGGACCTCGTCCAAGCGTGAGGCCCTG
GAGAAGACCATGAGGAACAAGATGGACAGTGAAATGAGACGGTTACAGGACTTTAACCGAGACC
TTAGAGAGAGATTGGAGTCCGCAAACCGCCACCTGGCAAGCAAGACCCAGGAAGCCCAGGCGGG
CAGTCAGGACATGGTGGCTAAACTGCTTGCTCAGAGCTATGAGCAGCAACAGGAGCAAGAGAAG
CTGGAGCGGGAGATGGCGCTGCTGCGTGGTGCCATCGAGGACCAGAGGCGACGGGCTGAACTGC
TGGAGCAGGCTCTGGGCAACGCGCAGAGCCGCGCCGCTCGAGCGGAGGAGGAGCTACGCAAGAA
GCAGGCCTACGTGGAGAAGGTGGAGCGGCTGCAGCAGGCGCTGGGACAGTTGCAGGCTGCTTGT
GAAAAGCGGGAGCAGCTGGAGCTGCGTCTGCGCACGCGCCTGGAGCAGGAACTCAAAGCCTTGC
GCGCGCAGCAGAGGCAGACAGGCACCCTCACAGGTGGTGGCGGTAGCCACACTGGGTCCACGGA
GCTCAGTGCCCTGCGACTGTCAGAACAGCTTCGGGAGAAGGAGGAACAGATACTGGCTCTAGAG
GCGGACATGACCAAGTGGGAACAAAAGTATTTGGAGGAACGGGCCATGAGGCAGTTTGCCATGG
ATGCGGCTGCCACTGCGGCTGCCCAGCGAGACACCACTCTCATCAGACACTCCCCCCAGCCCTC
GCCCAGCAGCAGTTTCAACGAAGGCCTGCTGGCAGGCAACCACAGGCACCAGGAGATGGAGAGC
AGGTTGAAGGTGCTCCATGCCCAGATCCTAGAGAAAGACGCAGTGATCAAGGTCCTTCAACAGC
GTTCCAGGAAAGACCCTGGCAAGGCTACCCAGGGCACCCTACGGCCCGCCAAGTCGGTGCCGTC
CATCTTTGCAGCTGCAGTGGGGACTCAGGGCTGGCAAGGGTTCTCAACCAGCGAGCGACAAACT
GATGCACCTGCCCGACAGACAGTAGACCGTGGACCAGCAGAAGAGCCCCCGGCCACACCTCCTC
TCCCTGCCCACACCAAACATGGCAGCAGAGACGGGAGCACCCAAACTGATGGCCCTGCAGACAG
CACCTCTGCCTGCTTGGCCTCAGAACCCGACAGCCTCCTGGGGTGCAACGGTAGCCAGAGGACA
ACCTCTCTGGACTCTATAGCTGCAACCAGAGTCCAGGATCTGTCAGACATGGTGGAAATACTGA
TCTGAAGGAAGGAGGCCTTGGGGACCCTGAAGCCTGGCTCCCCCATGGCATTCCAGCAATTGTC
TTCAAATGCTGCACCTCACTTCCTCCAACCAGCAATGGTTTGGTGCAGGAGCTCAGAGAGGAGC
ACTCCAGGGGAGCCAGAAAAGGCTGCACCCCCAGAAGACTGCTTTTTTTTGACCTATATTTCTC
CCACGACAATGAGGAAGGAAGAGGTCTGTTGCTGGAGCAGGAAGGGGCTGAGCCCCCTCCGTCC
TGCCAGTTTGTATTTGGGCATGAAGGGAAAGGAGACTGGATTCTGATTCCCAAGAATGGCTGGA
CACCAGCCAAATGGTCTGCAGGGATAATCAGGCCAAACCATGGTGTTCTGTGGCTAAGCATGGC
CCCAGCCAGCCCTAACTGCTCTCAGTCCCTCACTGCCTTCTTCAGATCACTAAGACTTGAATCT
TTTGGGGAACCATTGGGAGTGTGAGCCTTTCGGGAGCCACCAGCATGTCCCCTTGCTTGGAGTA
GGTTAGAGGCCATTTGAGAGGCCCGCAGAACAGTGTGTTTTGTATATAATTCTCTTTCCTTGGG
AACAGAAGACTAAGCATGCTGGTTCAGAGTCTCCTTCCAGAGCTGTGCTGCCTGCCCCTGCTTG
CCACAGTTCTTGAAACATTTGACAGGTCTACCAGATGTCCCTCTGCCTCCAGTTCTTGGCGGTG
TTTTTTTGATACTGGTTGCCTTTCCTCTGTTTTAAACCCCTGTGTTCAATGCCCGTGGGATTCT
TGTCACCAGCCTTTGTTGTGAACGGCTCCACCGCTCCTACCCCTGGGACATCCTGTCAGTTTGG
TTATAAACTGAGCCAGATGCGATGAGCCACAACAAGCGGATATCTGTCATACCCAGCCCCAGGT
TCTCTTTGAAGAAACTGGAGACGTTGTTCTCATAAACGTGTTCGTTCCCACCAGCAGGGACTGG
GAGAGGGAGCTATGCTGTTAAAAGTAATCGGTGAACTTAAAGAAAAGTCCCCACTAGGTGCCCC
CATCACAGAATGGCACCCAAGAGGCTGGCTCCTCGAGCTTTGGTGCCCCAGCCCTGAAGCAGGG
CCAGCTACTCGGAATTAGGCAGCCTACCAGCAGCAGTGACTTTAACTTCTGGTCTTAAAGTAAC
CCCCATTCAGCTGAAAAAGCGATTGGTGGATTGCAGATCTGTTGTGTTTTCTCTTGTTGTTTTG
TTCGTTTTTTCTCTCATTGTTTGAAGTTCTGTCTGTTGTTCCATTCCCATGGTTCTCCGTGTTT
CCTTTTTAAACATTTGCATTTGCTGGGCAATTGCGTATTTTTTTAATTCCCCTTTTCCCCTGTG
TAAAGCTGAGAAATACATCTGGTTCATGTGCGTTGTTTACAAAGATAAAAGTTTAAAAAAAAAA
CAAAAAAAAAGGAGGGAAAAACAAAAAATATCGTGAAAGAAAAAAAACAACTTAATATATTTTG
GATTAATATTTGGTATTTCTTTTAAAATATTTTTTTTGTGCTGTGAACGTTTTCTGCCAAAGAC
CATGACGTGTGTCTGTGTGTTTAAGTTATCATGAATATTTAAGGTGCAAACATGGCTGTTTTGT
CACGCCACTCTGTACCAGGATTGCCGAAGCATTCCACTGGGTATGACAGTATTTTAATAAAAAA
AAAAGCTTATACGGA

hide sequence

RefSeq Acc Id:

XM_039082102 ⟹ XP_038938030

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	8	112,182,823 - 112,198,032 (+)	NCBI
mRatBN7.2	8	103,303,946 - 103,319,161 (+)	NCBI

Protein Sequences


Protein RefSeqs	NP_113905	(Get FASTA)	NCBI Sequence Viewer
	XP_006243742	(Get FASTA)	NCBI Sequence Viewer
	XP_038938030	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAD56364	(Get FASTA)	NCBI Sequence Viewer
	EDL77396	(Get FASTA)	NCBI Sequence Viewer
	EDL77397	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000011347.5
	ENSRNOP00000075540
	ENSRNOP00000093935
GenBank Protein	G3V735	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

NP_113905 ⟸ NM_031717

- UniProtKB:

G3V735 (UniProtKB/Swiss-Prot), A0A0G2KAV3 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MRTLEDSSGTVLHRLIQEQLRYGNLTETRTLLAIQQQALRGGAGAGGTGSPQASLEIGAPEDSQ
VLQQATRQEPQGQEHQGGETHLAENRLYRLCPQPSKGEELPTYEEAKAHSQYYAAQQAGSRLHG
GDRDPRGASGGSRRQDEALRELRHGHVRSLSERLLQLSLERNGARVPSHMSSSHSFPQLARSQQ
GPQPRGPPAEGPEPRGPPPQYPHAVMAQETAAVNDPRYRPRSSPHFQHAEVRILQAQVPPVFLQ
QQQYQYLQQPQEHSPPLHPAALGHGPPSSFSPPALEGPPGAQATSGSAHLAQMESVLRENARLQ
RDNERLQRELESTSEKASCIEKLENEIQRLSEAHESLMRTSSKREALEKTMRNKMDSEMRRLQD
FNRDLRERLESANRHLASKTQEAQAGSQDMVAKLLAQSYEQQQEQEKLEREMALLRGAIEDQRR
RAELLEQALGNAQSRAARAEEELRKKQAYVEKVERLQQALGQLQAACEKREQLELRLRTRLEQE
LKALRAQQRQTGTLTGGGGSHTGSTELSALRLSEQLREKEEQILALEADMTKWEQKYLEERAMR
QFAMDAAATAAAQRDTTLIRHSPQPSPSSSFNEGLLAGNHRHQEMESRLKVLHAQILEKDAVIK
VLQQRSRKDPGKATQGTLRPAKSVPSIFAAAVGTQGWQGFSTSERQTDAPARQTVDRGPAEEPP
ATPPLPAHTKHGSRDGSTQTDGPADSTSACLASEPDSLLGCNGSQRTTSLDSIAATRVQDLSDM
VEILI

hide sequence

RefSeq Acc Id:	XP_006243742 ⟸ XM_006243680
- Peptide Label:	isoform X1
- UniProtKB:	A0A0G2KAV3 (UniProtKB/TrEMBL), A0A8I6AGR3 (UniProtKB/TrEMBL)
- Sequence:	show sequence MTGALRPGACWPLSRQVCASQRSMRTLEDSSGTVLHRLIQEQLRYGNLTETRTLLAIQQQALRG GAGAGGTGSPQASLEIGAPEDSQVLQQATRQEPQGQEHQGGETHLAENRLYRLCPQPSKGEELP TYEEAKAHSQYYAAQQAGSRLHGGDRDPRGASGGSRRQDEALRELRHGHVRSLSERLLQLSLER NGARVPSHMSSSHSFPQLARSQQGPQPRGPPAEGPEPRGPPPQYPHAVMAQETAAVNDPRYRPR SSPHFQHAEVRILQAQVPPVFLQQQQYQYLQQPQEHSPPLHPAALGHGPPSSFSPPALEGPPGA QATSGSAHLAQMESVLRENARLQRDNERLQRELESTSEKASCIEKLENEIQRLSEAHESLMRTS SKREALEKTMRNKMDSEMRRLQDFNRDLRERLESANRHLASKTQEAQAGSQDMVAKLLAQSYEQ QQEQEKLEREMALLRGAIEDQRRRAELLEQALGNAQSRAARAEEELRKKQAYVEKVERLQQALG QLQAACEKREQLELRLRTRLEQELKALRAQQRQTGTLTGGGGSHTGSTELSALRLSEQLREKEE QILALEADMTKWEQKYLEERAMRQFAMDAAATAAAQRDTTLIRHSPQPSPSSSFNEGLLAGNHR HQEMESRLKVLHAQILEKDAVIKVLQQRSRKDPGKATQGTLRPAKSVPSIFAAAVGTQGWQGFS TSERQTDAPARQTVDRGPAEEPPATPPLPAHTKHGSRDGSTQTDGPADSTSACLASEPDSLLGC NGSQRTTSLDSIAATRVQDLSDMVEILI hide sequence

Ensembl Acc Id:

ENSRNOP00000075540 ⟸ ENSRNOT00000090221

Ensembl Acc Id:

ENSRNOP00000011347 ⟸ ENSRNOT00000011347

RefSeq Acc Id:	XP_038938030 ⟸ XM_039082102
- Peptide Label:	isoform X2
- UniProtKB:	G3V735 (UniProtKB/Swiss-Prot), A0A0G2KAV3 (UniProtKB/TrEMBL)

Ensembl Acc Id:

ENSRNOP00000093935 ⟸ ENSRNOT00000094404

Protein Domains

Angiomotin C-terminal

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-G3V735-F1-model_v2	AlphaFold	G3V735	1-773	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13696226

Promoter ID:

EPDNEW_R6750

Type:

multiple initiation site

Name:

Amotl2_1

Description:

angiomotin like 2

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	8	111,210,800 - 111,210,860	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:70977	AgrOrtholog
BioCyc Gene	G2FUF-29347	BioCyc
Ensembl Genes	ENSRNOG00000008487	Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript	ENSRNOT00000011347.8	UniProtKB/Swiss-Prot
	ENSRNOT00000090221	ENTREZGENE
	ENSRNOT00000094404	ENTREZGENE
InterPro	Angiomotin	UniProtKB/Swiss-Prot
	Angiomotin-like_reg	UniProtKB/Swiss-Prot
	Angiomotin_C	UniProtKB/Swiss-Prot
KEGG Report	rno:65157	UniProtKB/Swiss-Prot
NCBI Gene	65157	ENTREZGENE
PANTHER	ANGIOMOTIN	UniProtKB/Swiss-Prot
	ANGIOMOTIN-LIKE PROTEIN 2	UniProtKB/Swiss-Prot
Pfam	Angiomotin_C	UniProtKB/Swiss-Prot
PhenoGen	Amotl2	PhenoGen
PRINTS	ANGIOMOTIN	UniProtKB/Swiss-Prot
RatGTEx	ENSRNOG00000008487	RatGTEx
UniProt	A0A0G2KAV3	ENTREZGENE, UniProtKB/TrEMBL
	A0A8I6AGR3	ENTREZGENE, UniProtKB/TrEMBL
	A6I2I1_RAT	UniProtKB/TrEMBL
	AMOL2_RAT	UniProtKB/Swiss-Prot, ENTREZGENE

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2002-07-09	Amotl2	angiomotin like 2			Symbol and Name updated to reflect Human and Mouse nomenclature	70877	APPROVED

RGD Curation Notes

Note Type	Note	Reference
gene_domains	human homolog is predicted to have an N-terminal Glutamine rich domain, two coiled-coil domains and a C-terminal PDZ binding domain, but appears to lack the angiostatin binding domain found between the coiled-coil regions and PDZ binding domain of angiomotin	634546
gene_expression	human homolog is expressed in all tissues examined except peripheral blood leukocytes and thymus; highest expression in placenta, followed by heart, skeletal muscle and kidney	1358128
gene_expression	mouse homolog shows highest expression in lung, followed by placenta	634546
gene_transcript	human homolog appears to have tissue-specific alternative transcripts expressed in heart and skeletal muscle	1358128

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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