Mbtps1 (membrane-bound transcription factor peptidase, site 1) - Rat Genome Database

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Gene: Mbtps1 (membrane-bound transcription factor peptidase, site 1) Rattus norvegicus
Analyze
Symbol: Mbtps1
Name: membrane-bound transcription factor peptidase, site 1
RGD ID: 70935
Description: Enables serine-type endopeptidase activity. Predicted to be involved in several processes, including lysosome organization; membrane protein intracellular domain proteolysis; and mitotic G2 DNA damage checkpoint signaling. Predicted to act upstream of or within lipid metabolic process. Predicted to be located in Golgi stack. Predicted to be active in Golgi membrane. Human ortholog(s) of this gene implicated in spondyloepiphyseal dysplasia Kondo-Fu type. Orthologous to human MBTPS1 (membrane bound transcription factor peptidase, site 1); PARTICIPATES IN sterol regulatory element-binding protein signaling pathway; Endoplasmic Reticulum-associated degradation pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-sulfonyldiphenol; ammonium chloride.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: endopeptidase S1P; membrane-bound transcription factor protease, site 1; membrane-bound transcription factor site-1 protease; S1p; S1P endopeptidase; site-1 protease; Ski-1; subtilisin/kexin isozyme 1
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81964,470,245 - 64,521,438 (-)NCBIGRCr8
mRatBN7.21947,561,598 - 47,612,769 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1947,561,598 - 47,612,791 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1954,356,280 - 54,407,076 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01955,037,157 - 55,087,952 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01957,250,566 - 57,301,596 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01952,146,507 - 52,206,310 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1952,146,808 - 52,206,310 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01962,894,989 - 62,954,792 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41949,751,424 - 49,802,700 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11949,756,304 - 49,807,581 (-)NCBI
Celera1946,820,963 - 46,871,847 (-)NCBICelera
Cytogenetic Map19q12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. Gene Data Set MGD Curation, June 12, 2002
4. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
5. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
6. Evolutionary conservation and adaptation in the mechanism that regulates SREBP action: what a long, strange tRIP it's been. Osborne TF and Espenshade PJ, Genes Dev. 2009 Nov 15;23(22):2578-91.
7. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
8. GOA pipeline RGD automated data pipeline
9. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
10. Mammalian subtilisin/kexin isozyme SKI-1: A widely expressed proprotein convertase with a unique cleavage specificity and cellular localization. Seidah NG, etal., Proc Natl Acad Sci U S A 1999 Feb 16;96(4):1321-6.
11. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
Additional References at PubMed
PMID:11069896   PMID:11163209   PMID:11717426   PMID:15938716   PMID:17643267   PMID:21719679   PMID:30046013   PMID:33738762   PMID:37358010  


Genomics

Comparative Map Data
Mbtps1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81964,470,245 - 64,521,438 (-)NCBIGRCr8
mRatBN7.21947,561,598 - 47,612,769 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1947,561,598 - 47,612,791 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1954,356,280 - 54,407,076 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01955,037,157 - 55,087,952 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01957,250,566 - 57,301,596 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01952,146,507 - 52,206,310 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1952,146,808 - 52,206,310 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01962,894,989 - 62,954,792 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41949,751,424 - 49,802,700 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11949,756,304 - 49,807,581 (-)NCBI
Celera1946,820,963 - 46,871,847 (-)NCBICelera
Cytogenetic Map19q12NCBI
MBTPS1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381684,053,763 - 84,116,942 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1684,053,761 - 84,116,942 (-)EnsemblGRCh38hg38GRCh38
GRCh371684,087,368 - 84,150,547 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361682,644,869 - 82,708,018 (-)NCBINCBI36Build 36hg18NCBI36
Build 341682,644,871 - 82,708,018NCBI
Celera1668,389,268 - 68,452,435 (-)NCBICelera
Cytogenetic Map16q23.3-q24.1NCBI
HuRef1669,841,352 - 69,904,502 (-)NCBIHuRef
CHM1_11685,498,381 - 85,561,902 (-)NCBICHM1_1
T2T-CHM13v2.01690,119,889 - 90,190,524 (-)NCBIT2T-CHM13v2.0
Mbtps1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm398120,234,890 - 120,285,603 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl8120,234,895 - 120,285,474 (-)EnsemblGRCm39 Ensembl
GRCm388119,508,151 - 119,558,864 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl8119,508,156 - 119,558,735 (-)EnsemblGRCm38mm10GRCm38
MGSCv378122,032,051 - 122,082,661 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv368122,394,132 - 122,444,704 (-)NCBIMGSCv36mm8
Celera8123,725,569 - 123,776,209 (-)NCBICelera
Cytogenetic Map8E1NCBI
cM Map867.85NCBI
Mbtps1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955564176,230 - 228,587 (+)EnsemblChiLan1.0
ChiLan1.0NW_004955564176,230 - 226,555 (+)NCBIChiLan1.0ChiLan1.0
MBTPS1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21893,800,904 - 93,863,994 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11699,718,041 - 99,781,111 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01664,719,971 - 64,783,119 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11684,063,508 - 84,126,000 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1684,063,508 - 84,126,000 (-)Ensemblpanpan1.1panPan2
MBTPS1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1568,228,176 - 68,281,175 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl568,228,238 - 68,280,515 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha568,242,379 - 68,295,248 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0568,526,299 - 68,579,190 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl568,526,329 - 68,579,190 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1568,474,058 - 68,526,939 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0568,310,640 - 68,363,509 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0568,726,354 - 68,779,243 (+)NCBIUU_Cfam_GSD_1.0
Mbtps1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934927,942,920 - 27,998,011 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366413,696,536 - 3,751,598 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366413,696,506 - 3,751,558 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MBTPS1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl64,503,565 - 4,558,609 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.164,503,530 - 4,558,601 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.265,085,217 - 5,140,266 (+)NCBISscrofa10.2Sscrofa10.2susScr3
MBTPS1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1569,464,064 - 69,527,588 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl569,463,920 - 69,527,541 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660476,231,679 - 6,295,208 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Mbtps1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247463,455,995 - 3,523,262 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247463,466,723 - 3,521,830 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Mbtps1
202 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:214
Count of miRNA genes:151
Interacting mature miRNAs:173
Transcripts:ENSRNOT00000020838
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1578764Stresp19Stress response QTL 193.60.001blood renin amount (VT:0003349)plasma renin activity level (CMO:0000116)191563020157337602Rat
61350Bp32Blood pressure QTL 320.012arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)192048357557337602Rat
5135224Leukc1Leukocyte quantity QTL 1eosinophil quantity (VT:0002602)blood eosinophil count (CMO:0000033)194434021455283277Rat
724546Kidm3Kidney mass QTL 33.1kidney mass (VT:0002707)calculated kidney weight (CMO:0000160)192932249057337602Rat
2317848Alcrsp21Alcohol response QTL 211.8999999761581420.05response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)19320477748204777Rat
7411549Bw130Body weight QTL 13050.001body mass (VT:0001259)body weight gain (CMO:0000420)191545586057337602Rat
1358200Insglur2Insulin/glucose ratio QTL 24.1blood glucose amount (VT:0000188)serum glucose level (CMO:0000543)193383821455283146Rat
724566Uae12Urinary albumin excretion QTL 125urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)19218792756457239Rat
1331737Uae29Urinary albumin excretion QTL 295.5urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)19409615555283277Rat
2298478Eau8Experimental allergic uveoretinitis QTL 80.0163uvea integrity trait (VT:0010551)experimental autoimmune uveitis score (CMO:0001504)191715443357337602Rat

Markers in Region
RH127834  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21947,561,709 - 47,561,912 (+)MAPPERmRatBN7.2
Rnor_6.01952,146,617 - 52,146,819NCBIRnor6.0
Rnor_5.01962,895,099 - 62,895,301UniSTSRnor5.0
RGSC_v3.41949,751,233 - 49,751,435UniSTSRGSC3.4
Celera1946,820,772 - 46,820,974UniSTS
RH 3.4 Map19653.0UniSTS
Cytogenetic Map19q12UniSTS
RH129347  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21947,561,672 - 47,561,857 (+)MAPPERmRatBN7.2
Rnor_6.01952,146,580 - 52,146,764NCBIRnor6.0
Rnor_5.01962,895,062 - 62,895,246UniSTSRnor5.0
RGSC_v3.41949,751,196 - 49,751,380UniSTSRGSC3.4
Celera1946,820,735 - 46,820,919UniSTS
RH 3.4 Map19652.8UniSTS
Cytogenetic Map19q12UniSTS
UniSTS:225106  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21947,601,467 - 47,601,642 (+)MAPPERmRatBN7.2
Rnor_6.01952,195,075 - 52,195,249NCBIRnor6.0
Rnor_6.01952,186,247 - 52,186,421NCBIRnor6.0
Rnor_5.01962,934,729 - 62,934,903UniSTSRnor5.0
Rnor_5.01962,943,557 - 62,943,731UniSTSRnor5.0
RGSC_v3.41949,791,465 - 49,791,639UniSTSRGSC3.4
Celera1946,860,612 - 46,860,786UniSTS
Cytogenetic Map19q12UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31

Sequence


Ensembl Acc Id: ENSRNOT00000020838   ⟹   ENSRNOP00000020838
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1947,561,601 - 47,612,791 (-)Ensembl
Rnor_6.0 Ensembl1952,147,127 - 52,186,260 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000087886   ⟹   ENSRNOP00000071317
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1947,561,598 - 47,612,723 (-)Ensembl
Rnor_6.0 Ensembl1952,146,808 - 52,206,310 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000108847   ⟹   ENSRNOP00000077523
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1947,561,606 - 47,612,703 (-)Ensembl
RefSeq Acc Id: NM_053569   ⟹   NP_446021
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81964,470,545 - 64,521,342 (-)NCBI
mRatBN7.21947,561,901 - 47,612,703 (-)NCBI
Rnor_6.01952,146,808 - 52,206,310 (-)NCBI
Rnor_5.01962,894,989 - 62,954,792 (-)NCBI
RGSC_v3.41949,751,424 - 49,802,700 (-)RGD
Celera1946,820,963 - 46,871,847 (-)RGD
Sequence:
RefSeq Acc Id: XM_008772651   ⟹   XP_008770873
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81964,477,978 - 64,521,438 (-)NCBI
mRatBN7.21947,569,334 - 47,612,769 (-)NCBI
Rnor_6.01952,154,222 - 52,187,411 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039098049   ⟹   XP_038953977
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81964,470,245 - 64,521,403 (-)NCBI
mRatBN7.21947,561,598 - 47,612,766 (-)NCBI
RefSeq Acc Id: XM_039098051   ⟹   XP_038953979
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81964,470,245 - 64,490,421 (-)NCBI
mRatBN7.21947,561,598 - 47,581,939 (-)NCBI
RefSeq Acc Id: NP_446021   ⟸   NM_053569
- Peptide Label: precursor
- UniProtKB: Q9WTZ3 (UniProtKB/Swiss-Prot),   G3V7Z2 (UniProtKB/Swiss-Prot),   A0A8L2R475 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008770873   ⟸   XM_008772651
- Peptide Label: isoform X1
- UniProtKB: A0A8I5XW81 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000071317   ⟸   ENSRNOT00000087886
Ensembl Acc Id: ENSRNOP00000020838   ⟸   ENSRNOT00000020838
RefSeq Acc Id: XP_038953977   ⟸   XM_039098049
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038953979   ⟸   XM_039098051
- Peptide Label: isoform X3
Ensembl Acc Id: ENSRNOP00000077523   ⟸   ENSRNOT00000108847
Protein Domains
Peptidase S8   Peptidase S8/S53

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q9WTZ3-F1-model_v2 AlphaFold Q9WTZ3 1-1052 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13701181
Promoter ID:EPDNEW_R11703
Type:initiation region
Name:Mbtps1_1
Description:membrane-bound transcription factor peptidase, site 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01952,206,316 - 52,206,376EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:70935 AgrOrtholog
BioCyc Gene G2FUF-5515 BioCyc
Ensembl Genes ENSRNOG00000015173 Ensembl, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ENSRNOG00055020994 UniProtKB/Swiss-Prot
  ENSRNOG00060022648 UniProtKB/Swiss-Prot
  ENSRNOG00065006633 UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000020838.8 UniProtKB/Swiss-Prot
  ENSRNOT00000087886.2 UniProtKB/TrEMBL
  ENSRNOT00000108847.1 UniProtKB/TrEMBL
  ENSRNOT00055035879 UniProtKB/Swiss-Prot
  ENSRNOT00060039310 UniProtKB/Swiss-Prot
  ENSRNOT00065010269 UniProtKB/Swiss-Prot
Gene3D-CATH 3.40.50.200 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:5623811 IMAGE-MGC_LOAD
InterPro Peptidase_S8/S53_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Peptidase_S8/S53_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Peptidase_S8_His-AS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Peptidase_S8_Ser-AS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Peptidase_S8_subtilisin-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Peptidase_S8_subtilisin-rel UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Site-1_peptidase_cat_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:89842 UniProtKB/Swiss-Prot
MGC_CLONE MGC:72356 IMAGE-MGC_LOAD
NCBI Gene 89842 ENTREZGENE
PANTHER MEMBRANE-BOUND TRANSCRIPTION FACTOR SITE-1 PROTEASE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PEPTIDASE S8 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam MBTP1_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Peptidase_S8 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Mbtps1 PhenoGen
PRINTS SUBTILISIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE SUBTILASE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SUBTILASE_HIS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SUBTILASE_SER UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RatGTEx ENSRNOG00000015173 RatGTEx
  ENSRNOG00055020994 RatGTEx
  ENSRNOG00060022648 RatGTEx
  ENSRNOG00065006633 RatGTEx
Superfamily-SCOP SSF52743 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A8I5XW81 ENTREZGENE, UniProtKB/TrEMBL
  A0A8L2R475 ENTREZGENE, UniProtKB/TrEMBL
  G3V7Z2 ENTREZGENE
  MBTP1_RAT UniProtKB/Swiss-Prot, ENTREZGENE
UniProt Secondary G3V7Z2 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2006-03-30 Mbtps1  membrane-bound transcription factor peptidase, site 1    membrane-bound transcription factor protease, site 1  Name updated 1299863 APPROVED
2002-07-09 Mbtps1  membrane-bound transcription factor protease, site 1      Symbol and Name updated to reflect Human and Mouse nomenclature 70877 APPROVED

RGD Curation Notes
Note Type Note Reference
gene_cellular_localization appears in the Golgi apparatus and within small punctate structures reminiscent of endosomes 70790