Ugt2b1 (UDP glucuronosyltransferase 2 family, polypeptide B1) - Rat Genome Database

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Gene: Ugt2b1 (UDP glucuronosyltransferase 2 family, polypeptide B1) Rattus norvegicus
Analyze
Symbol: Ugt2b1 (Ensembl: Ugt2b10)
Name: UDP glucuronosyltransferase 2 family, polypeptide B1 (Ensembl:UDP glucuronosyltransferase 2 family, polypeptide B10)
RGD ID: 708541
Description: Enables glucuronosyltransferase activity. Involved in several processes, including biphenyl catabolic process; cellular response to ethanol; and cellular response to testosterone stimulus. Predicted to be located in endoplasmic reticulum membrane. Predicted to be part of protein-containing complex. Orthologous to several human genes including UGT2B4 (UDP glucuronosyltransferase family 2 member B4); PARTICIPATES IN ascorbate and aldarate metabolic pathway; O-linked glycan biosynthetic pathway; pentose and glucuronate interconversion pathway; INTERACTS WITH (+)-schisandrin B; 1,2-dimethylhydrazine; 1-naphthaleneacetic acid.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: 2B1; liver UDP-glucuronosyltransferase, phenobarbital-inducible form; UDP glucuronosyltransferase 2 family, polypeptide B17; UDP glucuronosyltransferase family 2 member B17; UDP-glucuronosyltransferase 2B1; UDP-glucuronosyltransferase 2B4; UDPGT 2B1; UDPGTr-2; Udpgtr2; Ugt2b17
RGD Orthologs
Human
Mouse
Dog
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81421,378,882 - 21,390,631 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1421,378,853 - 21,392,331 (+)EnsemblGRCr8
mRatBN7.21421,024,035 - 21,035,784 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1421,024,006 - 21,035,986 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1421,363,252 - 21,374,999 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01422,682,188 - 22,693,935 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01421,213,270 - 21,225,017 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01422,724,399 - 22,736,148 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1422,724,070 - 22,825,444 (+)Ensemblrn6Rnor6.0
Rnor_5.01422,625,222 - 22,636,971 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41422,639,182 - 22,650,931 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1420,517,697 - 20,529,446 (+)NCBICelera
RGSC_v3.11422,639,181 - 22,650,931 (+)NCBI
Cytogenetic Map14p21NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-schisandrin B  (EXP)
(1->4)-beta-D-glucan  (ISO)
1,2-dichloroethane  (ISO)
1,2-dimethylhydrazine  (EXP)
1-naphthaleneacetic acid  (EXP)
1-naphthol  (EXP)
1-naphthyl isothiocyanate  (EXP)
17alpha-ethynylestradiol  (EXP)
17beta-estradiol  (EXP,ISO)
17beta-hydroxy-5alpha-androstan-3-one  (ISO)
2,2',4,4',5,5'-hexachlorobiphenyl  (EXP)
2,2',4,4'-Tetrabromodiphenyl ether  (EXP)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4-dibromophenyl 2,4,5-tribromophenyl ether  (ISO)
2,6-dinitrotoluene  (EXP)
2-Ethylhexanoic acid  (EXP)
2-Ethylphenol  (EXP)
2-naphthol  (EXP)
2-nitrofluorene  (EXP)
3-Ethylphenol  (EXP)
3-phenylpropionic acid  (EXP)
3H-1,2-dithiole-3-thione  (EXP)
4,4'-sulfonyldiphenol  (ISO)
4-(N-nitrosomethylamino)-1-(3-pyridyl)butan-1-one  (ISO)
4-ethylphenol  (EXP)
4-hydroxyphenyl retinamide  (ISO)
4-methylcyclohexan-1-ol  (EXP)
4-methylumbelliferone  (EXP,ISO)
4-methylumbelliferone beta-D-glucuronide  (ISO)
4-tert-butylphenol  (EXP)
5-methoxy-2-\{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl\}-1H-benzimidazole  (EXP)
6-propyl-2-thiouracil  (EXP)
8-Br-cAMP  (ISO)
acetamide  (EXP)
aflatoxin B1  (EXP,ISO)
aldrin  (ISO)
all-trans-retinoic acid  (ISO)
alpha-hexachlorocyclohexane  (EXP)
amentoflavone  (ISO)
amiodarone  (EXP)
amitriptyline  (EXP)
ammonium chloride  (EXP)
androstane-3,17-diol  (ISO)
androsterone  (ISO)
aristolochic acid A  (EXP)
Aroclor 1254  (EXP,ISO)
arsenous acid  (ISO)
atrazine  (EXP)
benzene  (EXP)
benzo[a]pyrene  (ISO)
benzyl alcohol  (EXP)
bezafibrate  (EXP)
bicalutamide  (ISO)
biphenyl-4-ol  (EXP)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
bisphenol AF  (ISO)
bisphenol F  (ISO)
bromuconazole  (EXP)
buta-1,3-diene  (ISO)
butylated hydroxyanisole  (ISO)
cadmium acetate  (EXP)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
calcitriol  (ISO)
carbamazepine  (EXP)
carbon nanotube  (ISO)
chloramphenicol  (EXP)
chlorogenic acid  (ISO)
chlorohydrocarbon  (EXP)
ciprofibrate  (EXP)
cis-caffeic acid  (ISO)
cisplatin  (EXP)
clofibrate  (EXP,ISO)
clofibric acid  (EXP)
clomipramine  (EXP)
cortisol  (EXP)
cyclosporin A  (ISO)
cylindrospermopsin  (ISO)
cyproconazole  (EXP)
daidzein  (ISO)
DDE  (EXP)
decabromodiphenyl ether  (EXP)
dexamethasone  (EXP)
diarsenic trioxide  (ISO)
dibutyl phthalate  (EXP)
dichloroacetic acid  (ISO)
diclofenac  (ISO)
diethylstilbestrol  (EXP,ISO)
Diosbulbin B  (ISO)
diquat  (ISO)
doxorubicin  (EXP)
elemental selenium  (EXP)
endosulfan  (EXP,ISO)
epoxiconazole  (EXP)
equol  (ISO)
ethyl methanesulfonate  (ISO)
eugenol  (ISO)
felbamate  (EXP)
fipronil  (EXP,ISO)
fluconazole  (EXP)
flumequine  (ISO)
flurbiprofen  (EXP)
flutamide  (EXP)
formaldehyde  (ISO)
fumonisin B1  (ISO)
gabapentin  (EXP)
genistein  (ISO)
glafenine  (EXP)
glutathione  (EXP)
hexachlorobenzene  (EXP)
hydratropic acid  (EXP)
ibuprofen  (EXP)
imipramine  (EXP)
indole-3-methanol  (EXP)
iron atom  (EXP)
iron(0)  (EXP)
ketoconazole  (EXP)
ketoprofen  (EXP)
L-ascorbic acid  (EXP)
lansoprazole  (EXP)
Lasiocarpine  (EXP)
Licochalcone A  (ISO)
lipopolysaccharide  (ISO)
lithocholic acid  (EXP)
lorcaserin  (ISO)
MeIQx  (ISO)
methyl methanesulfonate  (ISO)
methylmercury chloride  (EXP)
Mitotane  (EXP)
Muraglitazar  (EXP)
N-nitrosodiethylamine  (EXP,ISO)
N-Vinyl-2-pyrrolidone  (EXP)
naproxen  (EXP)
nefazodone  (EXP)
nelfinavir  (EXP)
nimesulide  (EXP)
Nonylphenol  (EXP)
O-methyleugenol  (ISO)
okadaic acid  (ISO)
oltipraz  (EXP,ISO)
omeprazole  (EXP)
orphenadrine  (EXP)
p-cresol  (EXP)
p-toluidine  (EXP)
pantoprazole  (EXP)
paracetamol  (EXP,ISO)
pectolinarigenin  (ISO)
perfluorooctane-1-sulfonic acid  (EXP,ISO)
perfluorooctanoic acid  (EXP,ISO)
phenformin  (EXP)
phenobarbital  (EXP,ISO)
phenytoin  (EXP)
phloretin  (ISO)
phlorizin  (ISO)
piperonyl butoxide  (EXP)
pirinixic acid  (EXP,ISO)
pirprofen  (EXP)
poly(I:C)  (EXP)
pravastatin  (EXP,ISO)
pregnenolone 16alpha-carbonitrile  (EXP)
prochloraz  (EXP)
propiconazole  (EXP,ISO)
quercetin 3-O-beta-D-galactopyranoside  (ISO)
quinolines  (EXP)
rabeprazole  (EXP)
rotenone  (EXP)
selenium atom  (EXP)
senecionine  (ISO)
sodium arsenite  (ISO)
tamoxifen  (EXP)
taurine  (EXP)
tert-butyl ethyl ether  (EXP)
Tesaglitazar  (EXP)
testosterone  (EXP,ISO)
Testosterone propionate  (EXP)
tetrachloromethane  (EXP,ISO)
thioacetamide  (EXP)
trans-caffeic acid  (ISO)
triadimefon  (EXP)
trichloroethene  (EXP,ISO)
trifluralin  (EXP)
triphenyl phosphate  (EXP)
trovafloxacin  (EXP)
uranium atom  (EXP)
ursodeoxycholic acid  (EXP,ISO)
valdecoxib  (EXP)
valproic acid  (EXP,ISO)
vinclozolin  (EXP)
vorinostat  (ISO)
warfarin  (ISO)
zaragozic acid A  (EXP,ISO)
zidovudine  (EXP)
zinc acetate  (EXP)
zinc atom  (EXP)
zinc(0)  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Effect of the acute phase response induced by endotoxin administration on the expression and activity of UGT isoforms in rats. Alkharfy KM, etal., Drug Metab Lett. 2008 Dec;2(4):248-55.
2. UDP-glucuronosyltransferase isoforms catalyzing glucuronidation of hydroxy-polychlorinated biphenyls in rat. Daidoji T, etal., Drug Metab Dispos. 2005 Oct;33(10):1466-76. Epub 2005 Jul 8.
3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
4. The pharmacokinetics of morphine and its glucuronide conjugate in a rat model of streptozotocin-induced diabetes and the expression of MRP2, MRP3 and UGT2B1 in the liver. Hasegawa Y, etal., J Pharm Pharmacol. 2010 Mar;62(3):310-4. doi: 10.1211/jpp.62.03.0004.
5. Protein-protein interactions between rat hepatic cytochromes P450 (P450s) and UDP-glucuronosyltransferases (UGTs): evidence for the functionally active UGT in P450-UGT complex. Ishii Y, etal., Drug Metab Pharmacokinet. 2007 Oct;22(5):367-76.
6. The configuration of the 17-hydroxy group variably influences the glucuronidation of beta-estradiol and epiestradiol by human UDP-glucuronosyltransferases. Itäaho K, etal., Drug Metab Dispos. 2008 Nov;36(11):2307-15. doi: 10.1124/dmd.108.022731. Epub 2008 Aug 21.
7. Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology Li Y, etal., Zhonghua Gan Zang Bing Za Zhi. 2001 Jun;9(3):172-4.
8. The effect of hormones on the expression of five isoforms of UDP-glucuronosyltransferase in primary cultures of rat hepatocytes. Li YQ, etal., Pharm Res. 1999 Feb;16(2):191-7.
9. Rat liver UDP-glucuronosyltransferase. Sequence and expression of a cDNA encoding a phenobarbital-inducible form. Mackenzie PI J Biol Chem 1986 May 5;261(13):6119-25.
10. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
11. Drug-drug interaction potential of antitumor acridine agent C-1748: The substrate of UDP-glucuronosyltransferases 2B7, 2B17 and the inhibitor of 1A9 and 2B7. Mróz A, etal., Pharmacol Rep. 2018 Sep;70(5):972-980. doi: 10.1016/j.pharep.2018.03.007. Epub 2018 Mar 22.
12. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
13. Glucuronidation of the lung carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol (NNAL) by rat UDP-glucuronosyltransferase 2B1. Ren Q, etal., Drug Metab Dispos. 1999 Sep;27(9):1010-6.
14. GOA pipeline RGD automated data pipeline
15. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
16. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:2113533   PMID:20308471   PMID:22579593   PMID:30107347  


Genomics

Comparative Map Data
Ugt2b1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81421,378,882 - 21,390,631 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1421,378,853 - 21,392,331 (+)EnsemblGRCr8
mRatBN7.21421,024,035 - 21,035,784 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1421,024,006 - 21,035,986 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1421,363,252 - 21,374,999 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01422,682,188 - 22,693,935 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01421,213,270 - 21,225,017 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01422,724,399 - 22,736,148 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1422,724,070 - 22,825,444 (+)Ensemblrn6Rnor6.0
Rnor_5.01422,625,222 - 22,636,971 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41422,639,182 - 22,650,931 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1420,517,697 - 20,529,446 (+)NCBICelera
RGSC_v3.11422,639,181 - 22,650,931 (+)NCBI
Cytogenetic Map14p21NCBI
UGT2B17
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38468,537,173 - 68,576,322 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl468,537,146 - 68,576,413 (-)Ensemblhg38GRCh38
GRCh37469,402,891 - 69,442,040 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36469,085,497 - 69,116,840 (-)NCBIBuild 36Build 36hg18NCBI36
Build 34469,231,670 - 69,263,011NCBI
Celera449,985,485 - 50,019,693 (-)NCBICelera
Cytogenetic Map4q13.2NCBI
CHM1_1469,439,588 - 69,470,934 (-)NCBICHM1_1
T2T-CHM13v2.0471,978,248 - 72,017,397 (-)NCBIT2T-CHM13v2.0
Ugt2b1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39587,064,498 - 87,074,362 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl587,064,497 - 87,074,389 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm38586,916,639 - 86,926,503 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl586,916,638 - 86,926,530 (-)Ensemblmm10GRCm38
MGSCv37587,345,664 - 87,355,528 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36587,991,200 - 88,001,064 (-)NCBIMGSCv36mm8
Celera584,136,470 - 84,146,336 (-)NCBICelera
Cytogenetic Map5E1NCBI
cM Map543.56NCBI
LOC480777
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11358,911,301 - 58,932,594 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1359,138,348 - 59,222,802 (-)EnsemblcanFam3CanFam3.1
CanFam3.1 Ensembl1359,138,348 - 59,222,802 (-)NCBIcanFam3CanFam3.1
Dog10K_Boxer_Tasha1358,815,272 - 58,952,673 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.01359,582,377 - 59,611,136 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
UMICH_Zoey_3.11359,229,309 - 59,258,028 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01358,712,846 - 58,741,639 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01359,733,225 - 59,761,990 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0

Variants

.
Variants in Ugt2b1
74 total Variants

QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1300114Srn2Serum renin concentration QTL 23.27blood renin amount (VT:0003349)plasma renin activity level (CMO:0000116)14395787821572472Rat
631528Scl11Serum cholesterol level QTL 114.9blood cholesterol amount (VT:0000180)blood total cholesterol level (CMO:0000051)141787564536079022Rat
7411573Bw139Body weight QTL 1394.70.001body mass (VT:0001259)body weight gain (CMO:0000420)14140068101Rat
9589814Gluco67Glucose level QTL 674.540.001blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)14140068101Rat
731183Pia20Pristane induced arthritis QTL 203.55joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)14939329839411170Rat
631212Bw5Body weight QTL55.43retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)141133490630674469Rat
2302277Gluco38Glucose level QTL 385.8blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)141133471628389666Rat
1331740Bw26Body weight QTL 263.028body mass (VT:0001259)body weight (CMO:0000012)14395787831121464Rat
1358296Ael3Aortic elastin QTL 33.70.00051aorta elastin amount (VT:0003905)aortic elastin14862139853621398Rat
61420Pia6Pristane induced arthritis QTL 64.9joint integrity trait (VT:0010548)arthritic paw count (CMO:0001460)141891545442433608Rat
70195Mcs8Mammary carcinoma susceptibility QTL 84.28mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)14395787824886169Rat
631839Niddm37Non-insulin dependent diabetes mellitus QTL 373.37blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)1411334716100078267Rat
2313397Coatc1Coat color QTL1coat/hair pigmentation trait (VT:0010463)coat/hair color measurement (CMO:0001808)141889519263895192Rat
631262Tcas4Tongue tumor susceptibility QTL 47.29tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)141790672654251504Rat
634352Apr6Acute phase response QTL 63.7blood interleukin-6 amount (VT:0008595)plasma interleukin-6 level (CMO:0001927)14141415516Rat
70204Niddm20Non-insulin dependent diabetes mellitus QTL 205.10.000008blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)14131893212Rat
2302045Pia39Pristane induced arthritis QTL 394.90.001blood immunoglobulin amount (VT:0002460)serum immunoglobulin G2a level (CMO:0002116)14862139853621398Rat
1300140Srn3Serum renin concentration QTL 33.19blood renin amount (VT:0003349)plasma renin activity level (CMO:0000116)141513759431238250Rat

Markers in Region
AA945116  
Rat AssemblyChrPosition (strand)SourceJBrowse
RH 3.4 Map14307.7UniSTS
Cytogenetic Map14p21UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
14 8 15 48 87 85 55 29 55 6 178 65 1 31 36 51 30 2 2

Sequence


Ensembl Acc Id: ENSRNOT00000002724   ⟹   ENSRNOP00000002724
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1421,378,856 - 21,390,622 (+)Ensembl
mRatBN7.2 Ensembl1421,024,035 - 21,035,784 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000089471   ⟹   ENSRNOP00000069054
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1421,378,853 - 21,390,833 (+)Ensembl
mRatBN7.2 Ensembl1421,024,006 - 21,035,986 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000139046   ⟹   ENSRNOP00000104488
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1421,378,873 - 21,392,331 (+)Ensembl
RefSeq Acc Id: NM_173295   ⟹   NP_775417
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81421,378,882 - 21,390,631 (+)NCBI
mRatBN7.21421,024,035 - 21,035,784 (+)NCBI
Rnor_6.01422,724,399 - 22,736,148 (+)NCBI
Rnor_5.01422,625,222 - 22,636,971 (+)NCBI
RGSC_v3.41422,639,182 - 22,650,931 (+)RGD
Celera1420,517,697 - 20,529,446 (+)RGD
Sequence:
Protein Sequences
Protein RefSeqs NP_775417 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAA42310 (Get FASTA)   NCBI Sequence Viewer  
  AAA42313 (Get FASTA)   NCBI Sequence Viewer  
  EDL89826 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000002724.2
  ENSRNOP00000104488
GenBank Protein P09875 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_775417   ⟸   NM_173295
- Peptide Label: precursor
- UniProtKB: P09875 (UniProtKB/Swiss-Prot),   A6JCQ4 (UniProtKB/TrEMBL),   A0A0G2JUD3 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000002724   ⟸   ENSRNOT00000002724
Ensembl Acc Id: ENSRNOP00000069054   ⟸   ENSRNOT00000089471
Ensembl Acc Id: ENSRNOP00000104488   ⟸   ENSRNOT00000139046

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P09875-F1-model_v2 AlphaFold P09875 1-529 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13699257
Promoter ID:EPDNEW_R9782
Type:multiple initiation site
Name:Ugt2b17_2
Description:UDP glucuronosyltransferase family 2 member B17
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_R9783  
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01422,724,389 - 22,724,449EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:708541 AgrOrtholog
BioCyc Gene G2FUF-16095 BioCyc
Ensembl Genes ENSRNOG00000001990 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000002724.4 UniProtKB/Swiss-Prot
  ENSRNOT00000139046 ENTREZGENE
Gene3D-CATH Glycogen Phosphorylase B UniProtKB/Swiss-Prot
InterPro UDP-glycosyltransferase UniProtKB/Swiss-Prot
  UDP_glucos_trans UniProtKB/Swiss-Prot
  UDP_glycos_trans_CS UniProtKB/Swiss-Prot
KEGG Report rno:286954 UniProtKB/Swiss-Prot
NCBI Gene 286954 ENTREZGENE
PANTHER EG:EG0003.4 PROTEIN-RELATED UniProtKB/Swiss-Prot
  UDP-GLUCURONOSYLTRANSFERASE 2B17-RELATED UniProtKB/Swiss-Prot
Pfam UDPGT UniProtKB/Swiss-Prot
PharmGKB UGT2B4 RGD
PhenoGen Ugt2b1 PhenoGen
PROSITE UDPGT UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000001990 RatGTEx
Superfamily-SCOP UDP-Glycosyltransferase/glycogen phosphorylase UniProtKB/Swiss-Prot
UniProt A0A0G2JUD3 ENTREZGENE, UniProtKB/TrEMBL
  A6JCQ4 ENTREZGENE, UniProtKB/TrEMBL
  P09875 ENTREZGENE, UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2023-03-31 Ugt2b1  UDP glucuronosyltransferase 2 family, polypeptide B1  Ugt2b17  UDP glucuronosyltransferase family 2 member B17  Name and Symbol changed 629549 APPROVED
2016-09-09 Ugt2b17  UDP glucuronosyltransferase family 2 member B17  Ugt2b17  UDP glucuronosyltransferase 2 family, polypeptide B17  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2013-02-04 Ugt2b17  UDP glucuronosyltransferase 2 family, polypeptide B17  Ugt2b1  UDP glucuronosyltransferase 2 family, polypeptide B1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2010-03-11 Ugt2b1  UDP glucuronosyltransferase 2 family, polypeptide B1  Ugt2b17  UDP glucuronosyltransferase 2 family, polypeptide B17  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-08-29 Ugt2b17  UDP glucuronosyltransferase 2 family, polypeptide B17  Ugt2b1  UDP glucuronosyltransferase 2 family, polypeptide B1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-03-07 Ugt2b1  UDP glucuronosyltransferase 2 family, polypeptide B1  Udpgtr2  liver UDP-glucuronosyltransferase, phenobarbital-inducible form  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-09-30 Udpgtr2        Symbol and Name status set to provisional 70820 PROVISIONAL