Has1 (hyaluronan synthase 1) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Behavioral & Substance Use Disorder Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)
Gene: Has1 (hyaluronan synthase 1) Rattus norvegicus
Analyze
Symbol: Has1
Name: hyaluronan synthase 1
RGD ID: 708528
Description: Predicted to enable hyaluronan synthase activity and identical protein binding activity. Involved in estrous cycle. Predicted to be located in Golgi apparatus and membrane. Predicted to be active in plasma membrane. Biomarker of pulmonary hypertension. Orthologous to human HAS1 (hyaluronan synthase 1); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; acrylamide; ammonium chloride.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: hyaluronan synthase1; LOC282821; similar to hyaluronan synthase1
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Allele / Splice: Has1m1Mcwi ; Has1m2Mcwi ; Has1m3Mcwi
Genetic Models: FHH-Has1m1Mcwi ; SS-Has1m2Mcwi ; SS-Has1m3Mcwi
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8167,366,460 - 67,378,686 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl167,366,460 - 67,378,444 (-)EnsemblGRCr8
mRatBN7.2158,693,411 - 58,705,653 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl158,693,411 - 58,705,397 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx163,518,026 - 63,530,014 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0172,210,671 - 72,222,664 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0165,428,072 - 65,440,064 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0159,720,612 - 59,732,409 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl159,720,612 - 59,732,409 (-)Ensemblrn6Rnor6.0
Rnor_5.0160,640,270 - 60,652,067 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4156,503,365 - 56,516,133 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera154,874,356 - 54,879,329 (-)NCBICelera
RGSC_v3.1156,506,309 - 56,519,078 (-)NCBI
Cytogenetic Map1q12NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytoplasm  (IEA,ISO)
Golgi apparatus  (ISO)
membrane  (IEA,ISO)
plasma membrane  (IBA,IEA,ISO)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Synthesis and fragmentation of hyaluronan in renal ischaemia. Decleves AE, etal., Nephrol Dial Transplant. 2012 Oct;27(10):3771-81. doi: 10.1093/ndt/gfs098. Epub 2012 Apr 23.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. Parallel up-regulation of FGF-2 and hyaluronan during development of cardiac hypertrophy in rat. Hellman U, etal., Cell Tissue Res. 2008 Jan 15;.
4. Mycobacteria exploit host hyaluronan for efficient extracellular replication. Hirayama Y, etal., PLoS Pathog. 2009 Oct;5(10):e1000643. doi: 10.1371/journal.ppat.1000643. Epub 2009 Oct 30.
5. Selective expression and functional characteristics of three mammalian hyaluronan synthases in oncogenic malignant transformation. Itano N, etal., J Biol Chem 2004 Apr 30;279(18):18679-87. Epub 2004 Jan 14.
6. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
7. The enzymatic degradation of hyaluronan is associated with disease progression in experimental pulmonary hypertension. Ormiston ML, etal., Am J Physiol Lung Cell Mol Physiol. 2010 Feb;298(2):L148-57. doi: 10.1152/ajplung.00097.2009. Epub 2009 Nov 13.
8. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
9. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
10. Involvement of hyaluronan synthesis in ovarian follicle growth in rats. Takahashi N, etal., Reproduction. 2013 Dec 19;147(2):189-97. doi: 10.1530/REP-13-0464. Print 2014 Feb.
Additional References at PubMed
PMID:10455188   PMID:10617644   PMID:17324121   PMID:19577615   PMID:24057227   PMID:25795779  


Genomics

Comparative Map Data
Has1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8167,366,460 - 67,378,686 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl167,366,460 - 67,378,444 (-)EnsemblGRCr8
mRatBN7.2158,693,411 - 58,705,653 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl158,693,411 - 58,705,397 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx163,518,026 - 63,530,014 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0172,210,671 - 72,222,664 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0165,428,072 - 65,440,064 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0159,720,612 - 59,732,409 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl159,720,612 - 59,732,409 (-)Ensemblrn6Rnor6.0
Rnor_5.0160,640,270 - 60,652,067 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4156,503,365 - 56,516,133 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera154,874,356 - 54,879,329 (-)NCBICelera
RGSC_v3.1156,506,309 - 56,519,078 (-)NCBI
Cytogenetic Map1q12NCBI
HAS1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381951,713,112 - 51,723,991 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1951,713,112 - 51,723,991 (-)Ensemblhg38GRCh38
GRCh371952,216,365 - 52,227,244 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361956,908,177 - 56,919,033 (-)NCBIBuild 36Build 36hg18NCBI36
Build 341956,908,176 - 56,919,033NCBI
Celera1949,265,901 - 49,276,762 (-)NCBICelera
Cytogenetic Map19q13.41NCBI
HuRef1948,547,305 - 48,558,022 (-)NCBIHuRef
CHM1_11952,218,163 - 52,229,047 (-)NCBICHM1_1
T2T-CHM13v2.01954,800,274 - 54,811,173 (-)NCBIT2T-CHM13v2.0
Has1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391718,063,588 - 18,075,450 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1718,063,585 - 18,075,467 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm381717,833,691 - 17,855,589 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1717,843,323 - 17,855,205 (-)Ensemblmm10GRCm38
MGSCv371717,980,290 - 17,992,152 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361717,547,941 - 17,559,804 (-)NCBIMGSCv36mm8
Celera1718,784,007 - 18,795,939 (-)NCBICelera
Cytogenetic Map17A3.2NCBI
cM Map1710.53NCBI
Has1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955558826,853 - 836,809 (+)Ensembl
ChiLan1.0NW_004955558826,853 - 836,809 (+)NCBIChiLan1.0ChiLan1.0
HAS1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22057,756,571 - 57,767,543 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11959,680,847 - 59,691,810 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01948,657,165 - 48,668,130 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11957,537,049 - 57,547,804 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1957,537,049 - 57,547,804 (-)EnsemblpanPan2panpan1.1
HAS1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11105,376,091 - 105,386,043 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1105,376,536 - 105,385,134 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha1104,949,702 - 104,959,564 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.01105,886,101 - 105,895,963 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1105,885,956 - 105,895,628 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11105,558,334 - 105,568,196 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01105,199,396 - 105,209,300 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01105,994,224 - 106,004,086 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Has1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244093494,768,242 - 4,775,106 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004937026125,881 - 135,235 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_004937026125,622 - 132,141 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
HAS1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl658,302,799 - 58,313,486 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1658,303,274 - 58,313,486 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2651,877,028 - 51,888,298 (-)NCBISscrofa10.2Sscrofa10.2susScr3
HAS1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1644,540,036 - 44,552,396 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl644,540,363 - 44,547,711 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366607324,594,280 - 24,606,885 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Has1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248323,329,920 - 3,336,290 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046248323,327,626 - 3,341,928 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Has1
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v12100,751,880 - 100,763,998 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Has1
45 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:61
Count of miRNA genes:55
Interacting mature miRNAs:58
Transcripts:ENSRNOT00000014824
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1331732Srn4Serum renin concentration QTL 44.467renin activity (VT:0005581)plasma renin activity level (CMO:0000116)14345783787558729Rat
1357397Bw41Body weight QTL 414.190.0001body mass (VT:0001259)body weight (CMO:0000012)12940927974409279Rat
1578649Bmd8Bone mineral density QTL 84.9femur mineral mass (VT:0010011)trabecular volumetric bone mineral density (CMO:0001729)151940904101229020Rat
1358359Sradr1Stress Responsive Adrenal Weight QTL 14.74adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)139728272132889942Rat
4889929Bss87Bone structure and strength QTL 876.7tibia area (VT:1000281)tibia-fibula cortical bone endosteal cross-sectional area (CMO:0001722)14630261591302615Rat
634314Niddm44Non-insulin dependent diabetes mellitus QTL 44blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)151941022208479811Rat
1331792Rf29Renal function QTL 294.589urine potassium amount (VT:0010539)urine potassium level (CMO:0000128)14345783787558729Rat
2313062Bmd73Bone mineral density QTL 733.90.0001tibia mineral mass (VT:1000283)compact volumetric bone mineral density (CMO:0001730)14630261591302615Rat
8552900Pigfal1Plasma insulin-like growth factor 1 level QTL 17.4blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)14350995288509952Rat
1578654Bss10Bone structure and strength QTL 104femur morphology trait (VT:0000559)femoral neck cortical cross-sectional area (CMO:0001702)151940904168768703Rat
1354643Foco2Food consumption QTL 27.170.0001eating behavior trait (VT:0001431)food intake rate (CMO:0000427)14212296887122968Rat
2313065Bss67Bone structure and strength QTL 673.10.0001tibia area (VT:1000281)tibia total energy absorbed before break (CMO:0001736)14630261591302615Rat
2313069Bss68Bone structure and strength QTL 682.90.0001tibia size trait (VT:0100001)tibia total energy absorbed before break (CMO:0001736)14630261591302615Rat
631495Bp96Blood pressure QTL 964.52arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)166404680111404680Rat
70225Bp58Blood pressure QTL 583.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)134184556172281316Rat
2313075Bss66Bone structure and strength QTL 663.40.0001tibia length (VT:0004357)tibia length (CMO:0000450)14630261591302615Rat
2298545Neuinf8Neuroinflammation QTL 84.6nervous system integrity trait (VT:0010566)spinal cord beta-2 microglobulin mRNA level (CMO:0002125)166009857160501508Rat
10059597Bp377Blood pressure QTL 3773.420.025arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)134565911208798288Rat
1331778Rf28Renal function QTL 284.66urine potassium amount (VT:0010539)urine potassium excretion rate (CMO:0000761)14345783787558729Rat
2313077Bss69Bone structure and strength QTL 693.50.0001tibia strength trait (VT:1000284)bone polar moment of inertia (CMO:0001558)14630261591302615Rat
1302788Scl19Serum cholesterol QTL 194.60.001blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)166400974132889942Rat
2313402Anxrr24Anxiety related response QTL 24aggression-related behavior trait (VT:0015014)tameness/aggressiveness composite score (CMO:0002136)151511344153680016Rat
1331785Rf27Renal function QTL 274.643urine sodium amount (VT:0006274)urine sodium level (CMO:0000129)13070837587558729Rat
61342Bp27Blood pressure QTL 273.40.0006arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)16540563796805205Rat
1300172Bp172Blood pressure QTL 1723.56arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)13456572679565726Rat
4889962Bss94Bone structure and strength QTL 943.8tibia area (VT:1000281)tibia-fibula cortical bone endosteal cross-sectional area (CMO:0001722)15190920691302615Rat
6903308Scl36Serum cholesterol QTL 3620.0125blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)158769992103769992Rat
2313092Bmd72Bone mineral density QTL 722.50.0001tibia mineral mass (VT:1000283)total volumetric bone mineral density (CMO:0001728)14630261591302615Rat
2300164Bmd44Bone mineral density QTL 445.40.0001lumbar vertebra mineral mass (VT:0010511)volumetric bone mineral density (CMO:0001553)166077886111077886Rat
2313097Bss70Bone structure and strength QTL 703.50.0001tibia strength trait (VT:1000284)tibia total energy absorbed before break (CMO:0001736)14630261591302615Rat
9589820Insglur3Insulin/glucose ratio QTL 310.750.001blood insulin amount (VT:0001560)calculated plasma insulin level (CMO:0002170)14350995288509952Rat
152025249Scl82Serum cholesterol level QTL 824.77blood cholesterol amount (VT:0000180)152891222109116986Rat
1354599Bw29Body weight QTL 293.460.001body mass (VT:0001259)body weight (CMO:0000012)14212296887122968Rat
4889919Bss86Bone structure and strength QTL 864.1tibia area (VT:1000281)tibia midshaft total cross-sectional area (CMO:0001715)14630261591302615Rat
8552948Pigfal11Plasma insulin-like growth factor 1 level QTL 114.7blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)14350995288509952Rat

Markers in Region
D1Got378  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr8167,378,962 - 67,379,119 (+)Marker Load Pipeline
mRatBN7.2158,705,915 - 58,706,072 (+)MAPPERmRatBN7.2
Rnor_6.0159,732,928 - 59,733,084NCBIRnor6.0
Rnor_5.0160,652,586 - 60,652,742UniSTSRnor5.0
RGSC_v3.4156,516,652 - 56,516,808UniSTSRGSC3.4
Cytogenetic Map1q12UniSTS


Genetic Models
This gene Has1 is modified in the following models/strains:
FHH-Has1m1Mcwi     SS-Has1m2Mcwi     SS-Has1m3Mcwi    


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
10 12 65 86 52 53 22 40 22 6 214 136 11 66 38 78 31 9 9

Sequence


Ensembl Acc Id: ENSRNOT00000014824   ⟹   ENSRNOP00000014824
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl167,366,460 - 67,378,444 (-)Ensembl
mRatBN7.2 Ensembl158,693,411 - 58,705,397 (-)Ensembl
Rnor_6.0 Ensembl159,720,612 - 59,732,409 (-)Ensembl
RefSeq Acc Id: NM_172323   ⟹   NP_758826
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8167,366,460 - 67,378,444 (-)NCBI
mRatBN7.2158,693,411 - 58,705,397 (-)NCBI
Rnor_6.0159,720,612 - 59,732,409 (-)NCBI
Rnor_5.0160,640,270 - 60,652,067 (-)NCBI
RGSC_v3.4156,503,365 - 56,516,133 (-)RGD
Celera154,874,356 - 54,879,329 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039102599   ⟹   XP_038958527
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8167,367,298 - 67,378,686 (-)NCBI
mRatBN7.2158,696,746 - 58,705,653 (-)NCBI
RefSeq Acc Id: NP_758826   ⟸   NM_172323
- UniProtKB: Q8CH93 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000014824   ⟸   ENSRNOT00000014824
RefSeq Acc Id: XP_038958527   ⟸   XM_039102599
- Peptide Label: isoform X1

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q8CH93-F1-model_v2 AlphaFold Q8CH93 1-583 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13689652
Promoter ID:EPDNEW_R175
Type:single initiation site
Name:Has1_1
Description:hyaluronan synthase 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0159,732,426 - 59,732,486EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:708528 AgrOrtholog
BioCyc Gene G2FUF-61255 BioCyc
Ensembl Genes ENSRNOG00000010994 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000014824 ENTREZGENE
  ENSRNOT00000014824.6 UniProtKB/TrEMBL
Gene3D-CATH Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A UniProtKB/TrEMBL
InterPro Nucleotide-diphossugar_trans UniProtKB/TrEMBL
KEGG Report rno:282821 UniProtKB/TrEMBL
NCBI Gene 282821 ENTREZGENE
PANTHER HYALURONAN SYNTHASE UniProtKB/TrEMBL
  PTHR22913:SF4 UniProtKB/TrEMBL
Pfam Glyco_tranf_2_3 UniProtKB/TrEMBL
PhenoGen Has1 PhenoGen
RatGTEx ENSRNOG00000010994 RatGTEx
Superfamily-SCOP SSF53448 UniProtKB/TrEMBL
UniProt A6KB72_RAT UniProtKB/TrEMBL
  Q8CH93 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2013-05-24 Has1  hyaluronan synthase 1  LOC688205  similar to hyaluronan synthase1  Data merged from RGD:1591217 1643240 APPROVED
2006-11-20 LOC688205  similar to hyaluronan synthase1      Symbol and Name status set to provisional 70820 PROVISIONAL
2005-07-08 Has1  hyaluronan synthase1  LOC282821    Symbol updated 1299863 APPROVED

RGD Curation Notes
Note Type Note Reference