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Gene: Ptpn7 (protein tyrosine phosphatase, non-receptor type 7) Rattus norvegicus

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Symbol:

Ptpn7

Name:

protein tyrosine phosphatase, non-receptor type 7

RGD ID:

708516

Description:

Predicted to enable protein tyrosine phosphatase activity. Predicted to be involved in signal transduction. Predicted to be located in cytoplasmic side of plasma membrane and cytosol. Orthologous to human PTPN7 (protein tyrosine phosphatase non-receptor type 7); PARTICIPATES IN mitogen activated protein kinase signaling pathway; INTERACTS WITH 1,3-dinitrobenzene; 2,3,7,8-tetrachlorodibenzodioxine; 2-methoxyethanol.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

hematopoietic protein-tyrosine phosphatase; Heptp; Lcptp; protein-tyrosine phosphatase LC-PTP; protein-tyrosine phosphatase, non-receptor type 7; tyrosine-protein phosphatase non-receptor type 7

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	PTPN7 (protein tyrosine phosphatase non-receptor type 7)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, PhylomeDB, Treefam
Mus musculus (house mouse):	Ptpn7 (protein tyrosine phosphatase, non-receptor type 7)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Ptpn7 (protein tyrosine phosphatase non-receptor type 7)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	PTPN7 (protein tyrosine phosphatase non-receptor type 7)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	PTPN7 (protein tyrosine phosphatase non-receptor type 7)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Ptpn7 (protein tyrosine phosphatase non-receptor type 7)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	PTPN7 (protein tyrosine phosphatase non-receptor type 7)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	PTPN7 (protein tyrosine phosphatase non-receptor type 7)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Ptpn7 (protein tyrosine phosphatase non-receptor type 7)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus rattus (black rat):	Ptpn7 (protein tyrosine phosphatase non-receptor type 7)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Other homologs ²
Homo sapiens (human):	HSPH1 (heat shock protein family H (Hsp110) member 1)	HGNC	OMA
Alliance orthologs ³
Mus musculus (house mouse):	Ptpn7 (protein tyrosine phosphatase, non-receptor type 7)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Homo sapiens (human):	PTPN7 (protein tyrosine phosphatase non-receptor type 7)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	ptprda (protein tyrosine phosphatase, receptor type, D, a)	Alliance	DIOPT (Ensembl Compara\|OMA)
Caenorhabditis elegans (roundworm):	C17H12.3	Alliance	DIOPT (Ensembl Compara\|OMA)
Caenorhabditis elegans (roundworm):	C17H12.3	Alliance	DIOPT (Ensembl Compara\|OMA\|OrthoFinder)
Saccharomyces cerevisiae (baker's yeast):	PTP1	Alliance	DIOPT (Ensembl Compara\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER)
Saccharomyces cerevisiae (baker's yeast):	PTP1	Alliance	DIOPT (Ensembl Compara\|OMA\|PANTHER)
Caenorhabditis elegans (roundworm):	C33H5.16	Alliance	DIOPT (Ensembl Compara\|OMA)
Caenorhabditis elegans (roundworm):	C33H5.16	Alliance	DIOPT (Ensembl Compara\|OMA\|OrthoFinder)
Saccharomyces cerevisiae (baker's yeast):	PTP3	Alliance	DIOPT (Ensembl Compara\|InParanoid\|PANTHER)
Caenorhabditis elegans (roundworm):	C55B7.3	Alliance	DIOPT (Ensembl Compara\|OMA)
Caenorhabditis elegans (roundworm):	C55B7.3	Alliance	DIOPT (Ensembl Compara\|OMA\|OrthoFinder)
Caenorhabditis elegans (roundworm):	F10G8.1	Alliance	DIOPT (Ensembl Compara\|OMA)
Caenorhabditis elegans (roundworm):	F10G8.1	Alliance	DIOPT (Ensembl Compara\|OMA\|OrthoFinder)
Caenorhabditis elegans (roundworm):	F47B3.7	Alliance	DIOPT (Ensembl Compara\|OMA)
Caenorhabditis elegans (roundworm):	F47B3.7	Alliance	DIOPT (Ensembl Compara\|OMA\|OrthoFinder)
Caenorhabditis elegans (roundworm):	K07F5.8	Alliance	DIOPT (Ensembl Compara\|OMA)
Caenorhabditis elegans (roundworm):	K07F5.8	Alliance	DIOPT (Ensembl Compara\|OMA\|OrthoFinder)
Caenorhabditis elegans (roundworm):	Y48G9A.9	Alliance	DIOPT (Ensembl Compara\|OMA)
Caenorhabditis elegans (roundworm):	Y48G9A.9	Alliance	DIOPT (Ensembl Compara\|OMA\|OrthoFinder)
Caenorhabditis elegans (roundworm):	ZK484.7	Alliance	DIOPT (Ensembl Compara\|OMA)
Caenorhabditis elegans (roundworm):	ZK484.7	Alliance	DIOPT (Ensembl Compara\|OMA\|OrthoFinder)
Drosophila melanogaster (fruit fly):	PTP-ER	Alliance	DIOPT (Ensembl Compara\|PANTHER)

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	13	49,122,679 - 49,136,096 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	13	49,122,609 - 49,136,094 (+)	Ensembl				GRCr8
mRatBN7.2	13	46,570,904 - 46,584,048 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	13	46,571,712 - 46,583,308 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	13	49,178,503 - 49,190,055 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	13	50,466,576 - 50,478,127 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	13	47,732,661 - 47,744,208 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	13	51,958,023 - 51,971,431 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	13	51,958,834 - 51,972,777 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	13	57,009,427 - 57,023,148 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	13	48,094,119 - 48,105,707 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	13	46,897,613 - 46,908,578 (+)	NCBI		Celera
RGSC_v3.1	13	48,108,161 - 48,119,750 (+)	NCBI
Cytogenetic Map	13	q13	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(+)-catechin (ISO)

(-)-alpha-phellandrene (ISO)

1,3-dinitrobenzene (EXP)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2-methoxyethanol (EXP)

4,4'-sulfonyldiphenol (ISO)

4-nitrophenol (ISO)

acetamide (EXP)

acrylamide (EXP)

aldehydo-D-glucose (ISO)

all-trans-retinoic acid (ISO)

alpha-amanitin (ISO)

alpha-phellandrene (ISO)

alpha-Zearalanol (EXP)

amitrole (EXP)

ammonium chloride (EXP)

amphetamine (EXP)

antirheumatic drug (ISO)

benzene (ISO)

benzo[e]pyrene (ISO)

bisphenol A (EXP,ISO)

Butylbenzyl phthalate (EXP)

choline (ISO)

Cuprizon (EXP)

curcumin (ISO)

D-glucose (ISO)

Dibutyl phosphate (ISO)

dichlorine (EXP)

dimethylarsinic acid (ISO)

dioxygen (ISO)

diquat (ISO)

diuron (ISO)

ethanol (ISO)

flavonoids (EXP)

folic acid (ISO)

fructose (ISO)

glucose (ISO)

glyphosate (ISO)

L-methionine (ISO)

lead(0) (ISO)

methapyrilene (ISO)

methylarsonic acid (ISO)

methylmercury chloride (EXP)

nickel atom (ISO)

ozone (EXP)

paclitaxel (ISO)

paracetamol (EXP,ISO)

rotenone (ISO)

silicon dioxide (ISO)

sodium arsenate (ISO)

sodium arsenite (ISO)

Soman (EXP)

tetracycline (ISO)

thioacetamide (EXP)

titanium dioxide (ISO)

trichloroethene (EXP)

trimellitic anhydride (ISO)

triphenyl phosphate (ISO)

triphenylstannane (ISO)

triptonide (ISO)

tungsten (ISO)

valproic acid (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

protein dephosphorylation (ISO)

signal transduction (IBA)

Cellular Component

cytoplasm (IEA,ISO)

cytoplasmic side of plasma membrane (IEA,ISO)

cytoskeleton (IEA)

cytosol (IEA,ISO)

Molecular Function

hydrolase activity (IEA)

phosphoprotein phosphatase activity (IEA)

protein binding (ISO)

protein tyrosine phosphatase activity (IBA,IEA)

Molecular Pathway Annotations Click to see Annotation Detail View

mitogen activated protein kinase signaling pathway (IEA)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	Rat ISS GO annotations from MGI mouse gene data--August 2006	MGD data from the GO Consortium
3.	KEGG Annotation Import Pipeline	Pipeline to import KEGG annotations from KEGG into RGD
4.	GOA pipeline	RGD automated data pipeline
5.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
6.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
7.	Aggregation of IgE receptors in rat basophilic leukemia 2H3 cells induces tyrosine phosphorylation of the cytosolic protein-tyrosine phosphatase HePTP.	Swieter M, etal., J Biol Chem 1995 Sep 15;270(37):21902-6.

Additional References at PubMed

PMID:10940933	PMID:11564869	PMID:14613483

Genomics

Comparative Map Data

Ptpn7
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	13	49,122,679 - 49,136,096 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	13	49,122,609 - 49,136,094 (+)	Ensembl				GRCr8
mRatBN7.2	13	46,570,904 - 46,584,048 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	13	46,571,712 - 46,583,308 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	13	49,178,503 - 49,190,055 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	13	50,466,576 - 50,478,127 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	13	47,732,661 - 47,744,208 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	13	51,958,023 - 51,971,431 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	13	51,958,834 - 51,972,777 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	13	57,009,427 - 57,023,148 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	13	48,094,119 - 48,105,707 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	13	46,897,613 - 46,908,578 (+)	NCBI		Celera
RGSC_v3.1	13	48,108,161 - 48,119,750 (+)	NCBI
Cytogenetic Map	13	q13	NCBI

PTPN7
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	1	202,147,013 - 202,161,588 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	1	202,147,012 - 202,161,588 (-)	Ensembl			hg38	GRCh38
GRCh37	1	202,116,141 - 202,130,716 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	1	200,382,766 - 200,396,374 (-)	NCBI	Build 36	Build 36	hg18	NCBI36
Celera	1	175,240,001 - 175,253,609 (-)	NCBI		Celera
Cytogenetic Map	1	q32.1	NCBI
HuRef	1	173,281,692 - 173,296,269 (-)	NCBI		HuRef
CHM1_1	1	203,538,425 - 203,553,000 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	1	201,404,580 - 201,419,169 (-)	NCBI		T2T-CHM13v2.0

Ptpn7
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	1	135,059,577 - 135,073,064 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	1	135,060,438 - 135,073,055 (+)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	1	135,131,838 - 135,145,328 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	1	135,132,700 - 135,145,317 (+)	Ensembl			mm10	GRCm38
MGSCv37	1	137,029,302 - 137,041,897 (+)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	1	136,949,136 - 136,961,731 (+)	NCBI		MGSCv36	mm8
Celera	1	137,759,680 - 137,772,179 (+)	NCBI		Celera
Cytogenetic Map	1	E4	NCBI
cM Map	1	58.24	NCBI

Ptpn7
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955406	38,232,589 - 38,250,195 (-)	Ensembl
ChiLan1.0	NW_004955406	38,233,409 - 38,249,940 (-)	NCBI	ChiLan1.0	ChiLan1.0

PTPN7
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	1	47,220,186 - 47,234,828 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	1	47,184,863 - 47,199,505 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	1	177,744,963 - 177,759,611 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	1	182,047,418 - 182,061,889 (-)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	1	182,049,084 - 182,061,151 (-)	Ensembl			panPan2	panpan1.1

PTPN7
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	7	859,124 - 869,168 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	7	859,214 - 869,183 (+)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	7	911,497 - 921,564 (+)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	7	867,172 - 877,245 (+)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	7	867,266 - 877,241 (+)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	7	855,561 - 865,624 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	7	963,852 - 973,174 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	7	987,836 - 997,900 (+)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Ptpn7
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024409344	73,146,132 - 73,158,479 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936567	2,382,931 - 2,391,542 (+)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936567	2,381,519 - 2,392,562 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

PTPN7
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	10	24,325,293 - 24,336,419 (-)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	10	24,325,289 - 24,336,426 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	10	28,744,132 - 28,748,147 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

PTPN7
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	25	27,243,907 - 27,258,088 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
Vero_WHO_p1.0	NW_023666055	28,023,104 - 28,038,993 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Ptpn7
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624807	8,575,371 - 8,593,552 (+)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
HetGla 1.0	NW_004624807	8,575,414 - 8,593,063 (+)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Ptpn7
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	10	566,175 - 576,253 (-)	NCBI		Rrattus_CSIRO_v1

Variants

Variants in Ptpn7
111 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	316
Count of miRNA genes:	197
Interacting mature miRNAs:	229
Transcripts:	ENSRNOT00000007833
Prediction methods:	Microtar, Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1298066	Bp159	Blood pressure QTL 159		0.004	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	13	48639634	93639634	Rat
10755495	Bp387	Blood pressure QTL 387	3.78		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	13	37216241	90057603	Rat
9589141	Insul28	Insulin level QTL 28	10.82	0.001	blood insulin amount (VT:0001560)	plasma insulin level (CMO:0000342)	13	11866254	56866254	Rat
6893344	Cm79	Cardiac mass QTL 79	1.5	0.04	heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	13	46272922	51216694	Rat
1354655	Bp241	Blood pressure QTL 241	3.9		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	13	38975045	103588154	Rat
70220	Bp55	Blood pressure QTL 55	5.75		arterial blood pressure trait (VT:2000000)	blood pressure measurement (CMO:0000003)	13	39924693	84924693	Rat
71119	Thym2	Thymus enlargement QTL 2	3.8		thymus mass (VT:0004954)	thymus weight to body weight ratio (CMO:0000612)	13	48749814	87285480	Rat
61391	Bp5	Blood pressure QTL 5	5.6		arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	13	24853925	69853925	Rat
4889861	Pur29	Proteinuria QTL 29	13.8	0.005	urine total protein amount (VT:0000032)	urine total protein excretion rate (CMO:0000756)	13	39968211	83286298	Rat
2317040	Aia21	Adjuvant induced arthritis QTL 21	2.75		joint integrity trait (VT:0010548)	left rear ankle joint diameter (CMO:0002149)	13	12384320	57384320	Rat
631645	Bp121	Blood pressure QTL 121	3.3		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	13	17468282	62468282	Rat
2317046	Aia8	Adjuvant induced arthritis QTL 8	3.9700000286102295		joint integrity trait (VT:0010548)	left rear ankle joint diameter (CMO:0002149)	13	12384320	57384320	Rat
619615	Bp80	Blood pressure QTL 80		0.0354	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	13	7421791	87286911	Rat
1331784	Bp222	Blood pressure QTL 222	2.944		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	13	24335432	55601132	Rat
61340	Bp25	Blood pressure QTL 25	4.2	0.004	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	13	37087983	82087983	Rat
1581573	Uae36	Urinary albumin excretion QTL 36			urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	13	6002008	88706694	Rat
1549897	Stresp12	Stress response QTL 12	3.35		stress-related behavior trait (VT:0010451)	number of approaches toward negative stimulus before onset of defensive burying response (CMO:0001960)	13	40983585	85983585	Rat
724564	Uae11	Urinary albumin excretion QTL 11	5.7		urine albumin amount (VT:0002871)	urine albumin level (CMO:0000130)	13	47354258	94285672	Rat
7207885	Glom27	Glomerulus QTL 27	3.9		kidney glomerulus integrity trait (VT:0010546)	kidney crescentic glomeruli count to kidney normal glomeruli count ratio (CMO:0002139)	13	21120177	109350286	Rat
4145117	Mcs27	Mammary carcinoma susceptibility QTL 27		0.0001	mammary gland integrity trait (VT:0010552)	post-insult time to mammary tumor formation (CMO:0000345)	13	45990077	50392939	Rat
1558644	Cm45	Cardiac mass QTL 45	3.6	0.002	heart mass (VT:0007028)	heart wet weight (CMO:0000069)	13	26244808	71244808	Rat
70181	BpQTLcluster11	Blood pressure QTL cluster 11	6.922		arterial blood pressure trait (VT:2000000)	absolute change in mean arterial blood pressure (CMO:0000533)	13	33794096	78794096	Rat
61349	Bp31	Blood pressure QTL 31	5.75		arterial blood pressure trait (VT:2000000)	blood pressure measurement (CMO:0000003)	13	39924693	84924693	Rat
2303563	Bw89	Body weight QTL 89	6		body mass (VT:0001259)	body weight (CMO:0000012)	13	34834947	79834947	Rat
1354621	Rf47	Renal function QTL 47	3.7		kidney renin amount (VT:0010559)	kidney renin level (CMO:0002166)	13	11081740	103588154	Rat
2301962	Cm72	Cardiac mass QTL 72	4.12		heart left ventricle mass (VT:0007031)	heart left ventricle weight (CMO:0000776)	13	33794096	60914504	Rat
1581554	Pur11	Proteinuria QTL 11			urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	13	6002008	88706694	Rat
12879477	Bp401	Blood pressure QTL 401			arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	13	39814726	84814726	Rat
1331750	Bp220	Blood pressure QTL 220	2.98		arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	13	39968211	84968211	Rat
6893338	Cm76	Cardiac mass QTL 76	0	0.99	heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	13	26244808	71244808	Rat
12879472	Bp399	Blood pressure QTL 399			arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	13	47780418	50392939	Rat
11530006	Niddm72	Non-insulin dependent diabetes mellitus QTL 72		0.001	blood glucose amount (VT:0000188)	blood glucose level area under curve (AUC) (CMO:0000350)	13	38286298	83286298	Rat
1354666	Bp244	Blood pressure QTL 244	4.9		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	13	1	103588154	Rat
9589164	Gluco66	Glucose level QTL 66	6.67	0.001	blood glucose amount (VT:0000188)	plasma glucose level (CMO:0000042)	13	17711336	62711336	Rat
7411662	Foco29	Food consumption QTL 29	20.8	0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	13	11866254	56866254	Rat

Markers in Region

BE112734

Rat Assembly	Chr	Position (strand)	Source	JBrowse
GRCr8	13	49,134,920 - 49,135,095 (+)	Marker Load Pipeline
mRatBN7.2	13	46,583,132 - 46,583,306 (+)	MAPPER	mRatBN7.2
Rnor_6.0	13	51,970,264 - 51,970,437	NCBI	Rnor6.0
Rnor_5.0	13	57,021,974 - 57,022,147	UniSTS	Rnor5.0
RGSC_v3.4	13	48,105,532 - 48,105,705	UniSTS	RGSC3.4
Celera	13	46,908,403 - 46,908,576	UniSTS
RH 3.4 Map	13	168.9	UniSTS
Cytogenetic Map	13	q13	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
16	12	67	160	91	90	59	92	59	6	356	192	11	139	81	92	31	17	17

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_145683	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006249820	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006249821	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	CH473958	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000013	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	U28356	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000007833 ⟹ ENSRNOP00000007833

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	13	49,122,675 - 49,135,106 (+)	Ensembl
mRatBN7.2 Ensembl	13	46,571,768 - 46,583,308 (+)	Ensembl
Rnor_6.0 Ensembl	13	51,958,834 - 51,972,777 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000114746 ⟹ ENSRNOP00000084393

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	13	49,123,538 - 49,136,094 (+)	Ensembl
mRatBN7.2 Ensembl	13	46,571,712 - 46,583,308 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000155289 ⟹ ENSRNOP00000103780

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	13	49,122,609 - 49,134,278 (+)	Ensembl

RefSeq Acc Id:

NM_145683 ⟹ NP_663716

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	13	49,123,558 - 49,135,096 (+)	NCBI
mRatBN7.2	13	46,571,768 - 46,583,308 (+)	NCBI
Rnor_6.0	13	51,958,877 - 51,970,439 (+)	NCBI
Rnor_5.0	13	57,009,427 - 57,023,148 (+)	NCBI
RGSC_v3.4	13	48,094,119 - 48,105,707 (+)	RGD
Celera	13	46,897,613 - 46,908,578 (+)	RGD

Sequence:

show sequence

AGACGGACTGACAGACAGCTGGCAAGAGGCAGCCCTGGGGACATAGCTGCTTCAGCAGGCCTCA
TGGCTGAGTGAGCCTCCCTTGGGCCCAGCAACCTACCCCAGCATGGTCCAGGCCTGTGAGGGGC
GCTCCAGAGCACAGCTGCCGACCTTGTCTTTGGGGGCAGACATGACTCAGCCTCCACCCGCCAA
AGCTCCAGCCAAGAAGCATGTGCGGCTGCAGGAGAGAAGGGGCTCCAGTGTGGCTCTGATGCTG
GATGTGCGGTCACTGGGCACTGTCGAGCCCATCTGCTCAGTGAACACACCCCGTGAAGTCACCC
TGCACTTCCTGCGCACAGCCGGGCACCCCCTTACACGCTGGACTCTACAGCACCAGCCTCCCAG
CCCCAAGCAGCTAGAAGAGGAATTCTTGAAGATCCCCTCAAACTTTGTCAACCCTGAAGACCTG
GATATCCCTGGCCATGCCTCCAAAGACCGATACAAGACCATCTTGCCAAATCCCCAGAGCCGTG
TCTGTCTTGGCCGGGCACACAGCCAGGAGGACAGCGACTACATCAATGCCAATTACATCCGGGG
CTATGATGGAAAGGAGAAGGTCTACATTGCTACCCAGGGCCCCATGCCCAACACTGTAGCAGAC
TTCTGGGAGATGGTGTGGCAGGAAGATGTATCCCTCATTGTCATGCTCACCCAGCTCCGAGAGG
GCAAGGAGAAATGTGTACACTACTGGCCCACAGAAGAGGAAGCCTATGGGCCCTTCCAGATCCG
CATCCAGGGCATGAAAGAGCACCCAGAATATACTGTGAGGCACCTCACCATTCAGCACCAACAG
GAATGCCGGTCAGTGAAACACATCCTCTTCTCAGCCTGGCCAGACCACCAGACGCCAGAATCAG
CCGGGCCCCTGCTGCGCCTGGTGGCTGAGGTGGAGACCCCAGAGACAGCTGCCAACTCCGGGCC
TATAGTGGTCCACTGCAGCGCAGGGATCGGTCGGACAGGCTGCTTCATCGCCACCCGAATCGGC
TGCCAGCAGCTGAAGGCCCGAGGGGAGGTGGACATTCTGGGCATTGTGTGCCAACTTCGCCTAG
ACAGAGGAGGCATGATCCAGACGGCGGAGCAGTACCAGTTCCTACACCACACTTTGGCCCTGTA
TGCAGCCCAGCTGCCCCCGGAGACCGACCCCTGACCCCTGACCCCTGACCCCTGACCCCTGACC
CTCCACCAGCCCAGGGACCAACCTTCTCTCAGGTCAGGGACAGTGGGTCTGGGGAAGTGGGCTG
TGCGCTCTGGCATGGCTTCTGCATAAGCACAGGAAAGGGAGCCTTGGAAGCAAGAATGTTTTAC
AGTCTCAGGAAACTGCCCCAGCAAGCAACAGGGGCCAGGCCGTAGGTCTTCGCCACAGACCATG
ACTCTGCCTTCTTCAGTGGCCCCCGGTGGACTCCAGGGGAGCTTCCCTAAGTGGCTCTGAACTT
ACAGATAGGAGCTGGTCCTTGAAATGGATTGAGAAAGCGGCTGAGGCACTGGCTTGTCTTTGTG
CTTCCTGTGGGCTCCTTTCCTTGTCGGTGACACAGAGTCAGTCCTTTGCTGCCATTGTAGAAGC
AGACAGAATGTTCCTGAAAGCCATTCCAGGTAGCCCTGCCGTTGGGGCTGCAGAGATGCTGATC
GTAAGATCCTCTTCCGGTAAGGCCTTGCCCACACACAGGCCAGATGCAAGCGCAGGGAAAATCC
CAGTCTGACCTTGGTCAAATCCTCTCTATTCTACATAGACTGCTCCTCCCCATACACCGGGGGG
TGCTGGATGACCCGCTCAGAAGAGAATAAAGGCCTTGGTTGGCCCCCCTCCACACCTGTGGTAA
AAGGAGACGCAGAGGTAACCAGGTCCAGCAGTTAGGAATCCCTGGAAGAGCCCAGGTGTGATGA
CCTACGTACTCATCCTCCAGCACTCAGGAGTAGAAGCAGGAGGATTGCTGCAAATTTGAGGCCA
GCTAGATCTATATTTTGAGTACCAGGCCAGACAGGACTACATAGCAAG

hide sequence

RefSeq Acc Id:

XM_006249820 ⟹ XP_006249882

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	13	49,124,028 - 49,136,096 (+)	NCBI
mRatBN7.2	13	46,572,239 - 46,584,048 (+)	NCBI
Rnor_6.0	13	51,958,955 - 51,971,431 (+)	NCBI
Rnor_5.0	13	57,009,427 - 57,023,148 (+)	NCBI

Sequence:

show sequence

CATCCCAGGACCCTGGGGTGGGAGGGGGTCTCCAAAGATGGGGTGAAGAAGCATGAGTTTGGGG
CTCCCATGCCTGGCCAGGGCATGAGAAGTGACATCTGGTGTCCCTGTGGCTGGAGGGCAAAGAA
GCCACACAGAGTGCCAGCAGAGGAGAGGCTAAAGGCCCCTTCCTGTTGTGGGCAAGTACTGTCC
CAGCCACACCTGCACCGGCCCACACTGTTCCCAAACCTCTGTCCCTGTGGGTTAGCAGCTCTAA
CCCCACCACCATAGCACCCACGACCTAGCTCTGAGAGACAGGGACTGCCCCAAAGGTGATGCTC
TCATCACCTCTATGGTCCCTCTCCCCTGCACCCCGAGCTGTAGCCTCACCATGCGCTGTCGCGC
TCTAGGGCTTAGTGAGGCCATTTCCTGTGACGGTTACAGAGGCGGGAGAGTGGGGGATGGGAAG
GAGGAGGGAGGAAGCACCCCTGGCCTACTGCCCTGGACAGAGACCCCATGAGCCACAACTGATC
TTGGAGCGGAACTGGCAGGCCTCATGGCTGAGTGAGCCTCCCTTGGGCCCAGCAACCTACCCCA
GCATGGTCCAGGCCTGTGAGGGGCGCTCCAGAGCACAGCTGCCGACCTTGTCTTTGGGGGCAGA
CATGACTCAGCCTCCACCCGCCAAAGCTCCAGCCAAGAAGCATGTGCGGCTGCAGGAGAGAAGG
GGCTCCAGTGTGGCTCTGATGCTGGATGTGCGGTCACTGGGCACTGTCGAGCCCATCTGCTCAG
TGAACACACCCCGTGAAGTCACCCTGCACTTCCTGCGCACAGCCGGGCACCCCCTTACACGCTG
GACTCTACAGCACCAGCCTCCCAGCCCCAAGCAGCTAGAAGAGGAATTCTTGAAGATCCCCTCA
AACTTTGTCAACCCTGAAGACCTGGATATCCCTGGCCATGCCTCCAAAGACCGATACAAGACCA
TCTTGCCAAATCCCCAGAGCCGTGTCTGTCTTGGCCGGGCACACAGCCAGGAGGACAGCGACTA
CATCAATGCCAATTACATCCGGGGCTATGATGGAAAGGAGAAGGTCTACATTGCTACCCAGGGC
CCCATGCCCAACACTGTAGCAGACTTCTGGGAGATGGTGTGGCAGGAAGATGTATCCCTCATTG
TCATGCTCACCCAGCTCCGAGAGGGCAAGGAGAAATGTGTACACTACTGGCCCACAGAAGAGGA
AGCCTATGGGCCCTTCCAGATCCGCATCCAGGGCATGAAAGAGCACCCAGAATATACTGTGAGG
CACCTCACCATTCAGCACCAACAGGAATGCCGGTCAGTGAAACACATCCTCTTCTCAGCCTGGC
CAGACCACCAGACGCCAGAATCAGCCGGGCCCCTGCTGCGCCTGGTGGCTGAGGTGGAGACCCC
AGAGACAGCTGCCAACTCCGGGCCTATAGTGGTCCACTGCAGCGCAGGGATCGGTCGGACAGGC
TGCTTCATCGCCACCCGAATCGGCTGCCAGCAGCTGAAGGCCCGAGGGGAGGTGGACATTCTGG
GCATTGTGTGCCAACTTCGCCTAGACAGAGGAGGCATGATCCAGACGGCGGAGCAGTACCAGTT
CCTACACCACACTTTGGCCCTGTATGCAGCCCAGCTGCCCCCGGAGACCGACCCCTGACCCCTG
ACCCCTGACCCCTGACCCCTGACCCTCCACCAGCCCAGGGACCAACCTTCTCTCAGGTCAGGGA
CAGTGGGTCTGGGGAAGTGGGCTGTGCGCTCTGGCATGGCTTCTGCATAAGCACAGGAAAGGGA
GCCTTGGAAGCAAGAATGTTTTACAGTCTCAGGAAACTGCCCCAGCAAGCAACAGGGGCCAGGC
CGTAGGTCTTCGCCACAGACCATGACTCTGCCTTCTTCAGTGGCCCCCGGTGGACTCCAGGGGA
GCTTCCCTAAGTGGCTCTGAACTTACAGATAGGAGCTGGTCCTTGAAATGGATTGAGAAAGCGG
CTGAGGCACTGGCTTGTCTTTGTGCTTCCTGTGGGCTCCTTTCCTTGTCGGTGACACAGAGTCA
GTCCTTTGCTGCCATTGTAGAAGCAGACAGAATGTTCCTGAAAGCCATTCCAGGTAGCCCTGCC
GTTGGGGCTGCAGAGATGCTGATCGTAAGATCCTCTTCCGGTAAGGCCTTGCCCACACACAGGC
CAGATGCAAGCGCAGGGAAAATCCCAGTCTGACCTTGGTCAAATCCTCTCTATTCTACATAGAC
TGCTCCTCCCCATACACCGGGGGGTGCTGGATGACCCGCTCAGAAGAGAATAAAGGCCTTGGTT
GGCCCCCCTCCACACCTGTGGTAAAAGGAGACGCAGAGGTAACCAGGTCCAGCAGTTAGGAATC
CCTGGAAGAGCCCAGGTGTGATGACCTACGTACTCATCCTCCAGCACTCAGGAGTAGAAGCAGG
AGGATTGCTGCAAATTTGAGGCCAGCTAGATCTATATTTTGAGTACCAGGCCAGACAGGACTAC
ATAGCAAGATCTTCTCTTAAAAAAAAAAAAAAAAAAAAAAAGCAATTTGAACTCTCTGGAGGAG
ATGGGGGGGGGGGGGGCTGCCTCTGCCTCCATGGCTTCCTTCCTGCTGTCATCTGCTCCCAACC
ACTCTCCGGGGAAAACCCAGCCTCTCTGCTTTGCTTCTGTGACTGACTTCAGAGCATCCTCTGG
GTACCCATGAAGTATCAAAGAAAGAGCAGAGGAGAGACAAAGAGCTGTGTCTGGTTCAAGAAAA
CCTACCTGCCATCTCTCCCTCCCCGGCTTGTATTTCTTTGCAGAGCCCTAGATTGCTTACCGGG
TCCCAGGAACAGACTGGGCTGTCACCACTTCAACCCTCATCCTCATCTCTTCAACACAGTTTTC
AGGGAGCCCACGATCTATCTCAGGGATGAACTACATACCCGAGAAAGCCAGGCCAACCCTGAGT
CTTCCTTGCTCCAGTTTGGACTGCCTGTGGGGAGGCAGGTGGAATGCTATTCCTCCTGTTTGGT
CTTCAGCCCCTAGATTGCTGCATGGTACAGTCCTCTGTGAAAACCCCAAGGAGTTGGAGGAGTG
ACTGCCCTCTTGCTTCCTGGCATCTCTCTGAAGAATGCGCAGTGTCGAAAGCCCGTGATCCACA
CTTGGACAGTGAAGACTGGAGAATCAGGAGTTCTGGACCGGCCTTGGCGATATGGCACCCTAGC
TCGAATACTAAACACACAAAATGAATGTGATGCTCCCACTGAGGCTAACATTCTGAGTGTCTGC
TTCTTTAGTCTTGGGGTGATGGCTTGCAGTTTTCTAAGTCCCCTAAAAGCTCAGCACTGCCCAA
GGTAGGCTTCTAAAGTATCCAATGCTACCATGAGCTCAGAGCCTGTCTGGAAGGGAGTGAGGGA
GGAAACTGCACAGCCCTATGGGCACCCTCCCTCTACAGTCACCCCAACCCCGTTCTAGAGGGCA
CAGGCTCTGGAAAAGCTAAATAAATAAATAACCTCTTGGA

hide sequence

RefSeq Acc Id:

XM_006249821 ⟹ XP_006249883

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	13	49,122,679 - 49,136,096 (+)	NCBI
mRatBN7.2	13	46,570,904 - 46,584,048 (+)	NCBI
Rnor_6.0	13	51,958,023 - 51,971,431 (+)	NCBI
Rnor_5.0	13	57,009,427 - 57,023,148 (+)	NCBI

Sequence:

show sequence

GCATGAACCACAAACCAGTTGGGCTGAGGGCCAGTGAAGGGCCTACCAAAGCCAGGCAGGGGTG
GGGGACTGTGGAGTCTTGAACTTGGAGACCGTTCCCTCCCCACACCCCAAGCATCCAAGTGGCC
CTGTGGTGAAGAGGACGTGAGACGTCTCTGATGTGAGGGCCACAGCCTTCGACTATCTGCAGGC
CTCATGGCTGAGTGAGCCTCCCTTGGGCCCAGCAACCTACCCCAGCATGGTCCAGGCCTGTGAG
GGGCGCTCCAGAGCACAGCTGCCGACCTTGTCTTTGGGGGCAGACATGACTCAGCCTCCACCCG
CCAAAGCTCCAGCCAAGAAGCATGTGCGGCTGCAGGAGAGAAGGGGCTCCAGTGTGGCTCTGAT
GCTGGATGTGCGGTCACTGGGCACTGTCGAGCCCATCTGCTCAGTGAACACACCCCGTGAAGTC
ACCCTGCACTTCCTGCGCACAGCCGGGCACCCCCTTACACGCTGGACTCTACAGCACCAGCCTC
CCAGCCCCAAGCAGCTAGAAGAGGAATTCTTGAAGATCCCCTCAAACTTTGTCAACCCTGAAGA
CCTGGATATCCCTGGCCATGCCTCCAAAGACCGATACAAGACCATCTTGCCAAATCCCCAGAGC
CGTGTCTGTCTTGGCCGGGCACACAGCCAGGAGGACAGCGACTACATCAATGCCAATTACATCC
GGGGCTATGATGGAAAGGAGAAGGTCTACATTGCTACCCAGGGCCCCATGCCCAACACTGTAGC
AGACTTCTGGGAGATGGTGTGGCAGGAAGATGTATCCCTCATTGTCATGCTCACCCAGCTCCGA
GAGGGCAAGGAGAAATGTGTACACTACTGGCCCACAGAAGAGGAAGCCTATGGGCCCTTCCAGA
TCCGCATCCAGGGCATGAAAGAGCACCCAGAATATACTGTGAGGCACCTCACCATTCAGCACCA
ACAGGAATGCCGGTCAGTGAAACACATCCTCTTCTCAGCCTGGCCAGACCACCAGACGCCAGAA
TCAGCCGGGCCCCTGCTGCGCCTGGTGGCTGAGGTGGAGACCCCAGAGACAGCTGCCAACTCCG
GGCCTATAGTGGTCCACTGCAGCGCAGGGATCGGTCGGACAGGCTGCTTCATCGCCACCCGAAT
CGGCTGCCAGCAGCTGAAGGCCCGAGGGGAGGTGGACATTCTGGGCATTGTGTGCCAACTTCGC
CTAGACAGAGGAGGCATGATCCAGACGGCGGAGCAGTACCAGTTCCTACACCACACTTTGGCCC
TGTATGCAGCCCAGCTGCCCCCGGAGACCGACCCCTGACCCCTGACCCCTGACCCCTGACCCCT
GACCCTCCACCAGCCCAGGGACCAACCTTCTCTCAGGTCAGGGACAGTGGGTCTGGGGAAGTGG
GCTGTGCGCTCTGGCATGGCTTCTGCATAAGCACAGGAAAGGGAGCCTTGGAAGCAAGAATGTT
TTACAGTCTCAGGAAACTGCCCCAGCAAGCAACAGGGGCCAGGCCGTAGGTCTTCGCCACAGAC
CATGACTCTGCCTTCTTCAGTGGCCCCCGGTGGACTCCAGGGGAGCTTCCCTAAGTGGCTCTGA
ACTTACAGATAGGAGCTGGTCCTTGAAATGGATTGAGAAAGCGGCTGAGGCACTGGCTTGTCTT
TGTGCTTCCTGTGGGCTCCTTTCCTTGTCGGTGACACAGAGTCAGTCCTTTGCTGCCATTGTAG
AAGCAGACAGAATGTTCCTGAAAGCCATTCCAGGTAGCCCTGCCGTTGGGGCTGCAGAGATGCT
GATCGTAAGATCCTCTTCCGGTAAGGCCTTGCCCACACACAGGCCAGATGCAAGCGCAGGGAAA
ATCCCAGTCTGACCTTGGTCAAATCCTCTCTATTCTACATAGACTGCTCCTCCCCATACACCGG
GGGGTGCTGGATGACCCGCTCAGAAGAGAATAAAGGCCTTGGTTGGCCCCCCTCCACACCTGTG
GTAAAAGGAGACGCAGAGGTAACCAGGTCCAGCAGTTAGGAATCCCTGGAAGAGCCCAGGTGTG
ATGACCTACGTACTCATCCTCCAGCACTCAGGAGTAGAAGCAGGAGGATTGCTGCAAATTTGAG
GCCAGCTAGATCTATATTTTGAGTACCAGGCCAGACAGGACTACATAGCAAGATCTTCTCTTAA
AAAAAAAAAAAAAAAAAAAAAGCAATTTGAACTCTCTGGAGGAGATGGGGGGGGGGGGGGCTGC
CTCTGCCTCCATGGCTTCCTTCCTGCTGTCATCTGCTCCCAACCACTCTCCGGGGAAAACCCAG
CCTCTCTGCTTTGCTTCTGTGACTGACTTCAGAGCATCCTCTGGGTACCCATGAAGTATCAAAG
AAAGAGCAGAGGAGAGACAAAGAGCTGTGTCTGGTTCAAGAAAACCTACCTGCCATCTCTCCCT
CCCCGGCTTGTATTTCTTTGCAGAGCCCTAGATTGCTTACCGGGTCCCAGGAACAGACTGGGCT
GTCACCACTTCAACCCTCATCCTCATCTCTTCAACACAGTTTTCAGGGAGCCCACGATCTATCT
CAGGGATGAACTACATACCCGAGAAAGCCAGGCCAACCCTGAGTCTTCCTTGCTCCAGTTTGGA
CTGCCTGTGGGGAGGCAGGTGGAATGCTATTCCTCCTGTTTGGTCTTCAGCCCCTAGATTGCTG
CATGGTACAGTCCTCTGTGAAAACCCCAAGGAGTTGGAGGAGTGACTGCCCTCTTGCTTCCTGG
CATCTCTCTGAAGAATGCGCAGTGTCGAAAGCCCGTGATCCACACTTGGACAGTGAAGACTGGA
GAATCAGGAGTTCTGGACCGGCCTTGGCGATATGGCACCCTAGCTCGAATACTAAACACACAAA
ATGAATGTGATGCTCCCACTGAGGCTAACATTCTGAGTGTCTGCTTCTTTAGTCTTGGGGTGAT
GGCTTGCAGTTTTCTAAGTCCCCTAAAAGCTCAGCACTGCCCAAGGTAGGCTTCTAAAGTATCC
AATGCTACCATGAGCTCAGAGCCTGTCTGGAAGGGAGTGAGGGAGGAAACTGCACAGCCCTATG
GGCACCCTCCCTCTACAGTCACCCCAACCCCGTTCTAGAGGGCACAGGCTCTGGAAAAGCTAAA
TAAATAAATAACCTCTTGGA

hide sequence

Protein Sequences


Protein RefSeqs	NP_663716	(Get FASTA)	NCBI Sequence Viewer
	XP_006249882	(Get FASTA)	NCBI Sequence Viewer
	XP_006249883	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAA84443	(Get FASTA)	NCBI Sequence Viewer
	EDM09706	(Get FASTA)	NCBI Sequence Viewer
	EDM09707	(Get FASTA)	NCBI Sequence Viewer
	EDM09708	(Get FASTA)	NCBI Sequence Viewer
	EDM09709	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000007833.1
	ENSRNOP00000084393
	ENSRNOP00000103780
GenBank Protein	P49445	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

NP_663716 ⟸ NM_145683

- UniProtKB:

P49445 (UniProtKB/Swiss-Prot), A6ICD8 (UniProtKB/TrEMBL), A6ICE0 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MVQACEGRSRAQLPTLSLGADMTQPPPAKAPAKKHVRLQERRGSSVALMLDVRSLGTVEPICSV
NTPREVTLHFLRTAGHPLTRWTLQHQPPSPKQLEEEFLKIPSNFVNPEDLDIPGHASKDRYKTI
LPNPQSRVCLGRAHSQEDSDYINANYIRGYDGKEKVYIATQGPMPNTVADFWEMVWQEDVSLIV
MLTQLREGKEKCVHYWPTEEEAYGPFQIRIQGMKEHPEYTVRHLTIQHQQECRSVKHILFSAWP
DHQTPESAGPLLRLVAEVETPETAANSGPIVVHCSAGIGRTGCFIATRIGCQQLKARGEVDILG
IVCQLRLDRGGMIQTAEQYQFLHHTLALYAAQLPPETDP

hide sequence

RefSeq Acc Id:	XP_006249883 ⟸ XM_006249821
- Peptide Label:	isoform X2
- UniProtKB:	P49445 (UniProtKB/Swiss-Prot), A6ICD8 (UniProtKB/TrEMBL), A6ICE0 (UniProtKB/TrEMBL)
- Sequence:	show sequence MVQACEGRSRAQLPTLSLGADMTQPPPAKAPAKKHVRLQERRGSSVALMLDVRSLGTVEPICSV NTPREVTLHFLRTAGHPLTRWTLQHQPPSPKQLEEEFLKIPSNFVNPEDLDIPGHASKDRYKTI LPNPQSRVCLGRAHSQEDSDYINANYIRGYDGKEKVYIATQGPMPNTVADFWEMVWQEDVSLIV MLTQLREGKEKCVHYWPTEEEAYGPFQIRIQGMKEHPEYTVRHLTIQHQQECRSVKHILFSAWP DHQTPESAGPLLRLVAEVETPETAANSGPIVVHCSAGIGRTGCFIATRIGCQQLKARGEVDILG IVCQLRLDRGGMIQTAEQYQFLHHTLALYAAQLPPETDP hide sequence

RefSeq Acc Id:

XP_006249882 ⟸ XM_006249820

- Peptide Label:

isoform X1

- Sequence:

show sequence

MGRRREEAPLAYCPGQRPHEPQLILERNWQASWLSEPPLGPATYPSMVQACEGRSRAQLPTLSL
GADMTQPPPAKAPAKKHVRLQERRGSSVALMLDVRSLGTVEPICSVNTPREVTLHFLRTAGHPL
TRWTLQHQPPSPKQLEEEFLKIPSNFVNPEDLDIPGHASKDRYKTILPNPQSRVCLGRAHSQED
SDYINANYIRGYDGKEKVYIATQGPMPNTVADFWEMVWQEDVSLIVMLTQLREGKEKCVHYWPT
EEEAYGPFQIRIQGMKEHPEYTVRHLTIQHQQECRSVKHILFSAWPDHQTPESAGPLLRLVAEV
ETPETAANSGPIVVHCSAGIGRTGCFIATRIGCQQLKARGEVDILGIVCQLRLDRGGMIQTAEQ
YQFLHHTLALYAAQLPPETDP

hide sequence

Ensembl Acc Id:

ENSRNOP00000007833 ⟸ ENSRNOT00000007833

Ensembl Acc Id:

ENSRNOP00000084393 ⟸ ENSRNOT00000114746

Ensembl Acc Id:

ENSRNOP00000103780 ⟸ ENSRNOT00000155289

Protein Domains

Tyrosine specific protein phosphatases Tyrosine-protein phosphatase

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-P49445-F1-model_v2	AlphaFold	P49445	1-359	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13698838

Promoter ID:

EPDNEW_R9362

Type:

multiple initiation site

Name:

Ptpn7_1

Description:

protein tyrosine phosphatase, non-receptor type 7

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	13	51,958,877 - 51,958,937	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:708516	AgrOrtholog
BioCyc Gene	G2FUF-18218	BioCyc
Ensembl Genes	ENSRNOG00000005807	Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript	ENSRNOT00000007833.4	UniProtKB/Swiss-Prot
	ENSRNOT00000114746	ENTREZGENE
	ENSRNOT00000155289	ENTREZGENE
Gene3D-CATH	3.90.190.10	UniProtKB/Swiss-Prot
InterPro	Prot-tyrosine_phosphatase-like	UniProtKB/Swiss-Prot
	PTPase_domain	UniProtKB/Swiss-Prot
	Tyr_Pase_AS	UniProtKB/Swiss-Prot
	Tyr_Pase_cat	UniProtKB/Swiss-Prot
	Tyr_Pase_KIM-con	UniProtKB/Swiss-Prot
	TYR_PHOSPHATASE_dom	UniProtKB/Swiss-Prot
KEGG Report	rno:246781	UniProtKB/Swiss-Prot
NCBI Gene	246781	ENTREZGENE
PANTHER	PROTEIN-TYROSINE-PHOSPHATASE	UniProtKB/Swiss-Prot
	PTHR46198	UniProtKB/Swiss-Prot
Pfam	Y_phosphatase	UniProtKB/Swiss-Prot
PhenoGen	Ptpn7	PhenoGen
PRINTS	KIMPTPASE	UniProtKB/Swiss-Prot
	PRTYPHPHTASE	UniProtKB/Swiss-Prot
PROSITE	TYR_PHOSPHATASE_1	UniProtKB/Swiss-Prot
	TYR_PHOSPHATASE_2	UniProtKB/Swiss-Prot
	TYR_PHOSPHATASE_PTP	UniProtKB/Swiss-Prot
RatGTEx	ENSRNOG00000005807	RatGTEx
SMART	PTPc	UniProtKB/Swiss-Prot
	PTPc_motif	UniProtKB/Swiss-Prot
Superfamily-SCOP	SSF52799	UniProtKB/Swiss-Prot
UniProt	A0A8I5ZXS3_RAT	UniProtKB/TrEMBL
	A0ABK0L3G4_RAT	UniProtKB/TrEMBL
	A6ICD8	ENTREZGENE, UniProtKB/TrEMBL
	A6ICE0	ENTREZGENE, UniProtKB/TrEMBL
	A6ICE1_RAT	UniProtKB/TrEMBL
	P49445	ENTREZGENE, UniProtKB/Swiss-Prot

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2005-07-08	Ptpn7	protein tyrosine phosphatase, non-receptor type 7	Lcptp	protein-tyrosine phosphatase, non-receptor type 7	Symbol and Name updated	1299863	APPROVED

RGD Curation Notes

Note Type	Note	Reference

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Annotations - KEGG (archival)