PTPN7 (protein tyrosine phosphatase non-receptor type 7) - Rat Genome Database

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Gene: PTPN7 (protein tyrosine phosphatase non-receptor type 7) Chlorocebus sabaeus
Analyze
Symbol: PTPN7
Name: protein tyrosine phosphatase non-receptor type 7
RGD ID: 18700401
Description: ENCODES a protein that exhibits protein kinase binding (inferred); protein tyrosine phosphatase activity (inferred); INVOLVED IN signal transduction (inferred); ASSOCIATED WITH familial adult myoclonic epilepsy 5 (ortholog); gastrointestinal stromal tumor (ortholog); Hypokalemic Periodic Paralysis, Type 1 (ortholog); FOUND IN cell junction (inferred); cytoplasm (inferred); cytoplasmic side of plasma membrane (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: tyrosine-protein phosphatase non-receptor type 7
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12527,243,907 - 27,258,088 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366605528,023,104 - 28,038,993 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
PTPN7
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12527,243,907 - 27,258,088 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366605528,023,104 - 28,038,993 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
PTPN7
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381202,147,013 - 202,161,588 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1202,147,013 - 202,161,588 (-)EnsemblGRCh38hg38GRCh38
GRCh371202,116,141 - 202,130,716 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361200,382,766 - 200,396,374 (-)NCBINCBI36Build 36hg18NCBI36
Celera1175,240,001 - 175,253,609 (-)NCBICelera
Cytogenetic Map1q32.1NCBI
HuRef1173,281,692 - 173,296,269 (-)NCBIHuRef
CHM1_11203,538,425 - 203,553,000 (-)NCBICHM1_1
T2T-CHM13v2.01201,404,580 - 201,419,169 (-)NCBIT2T-CHM13v2.0
Ptpn7
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391135,059,577 - 135,073,064 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1135,060,438 - 135,073,055 (+)EnsemblGRCm39 Ensembl
GRCm381135,131,838 - 135,145,328 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1135,132,700 - 135,145,317 (+)EnsemblGRCm38mm10GRCm38
MGSCv371137,029,302 - 137,041,897 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361136,949,136 - 136,961,731 (+)NCBIMGSCv36mm8
Celera1137,759,680 - 137,772,179 (+)NCBICelera
Cytogenetic Map1E4NCBI
cM Map158.24NCBI
Ptpn7
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81349,122,679 - 49,136,096 (+)NCBIGRCr8
mRatBN7.21346,570,904 - 46,584,048 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1346,571,712 - 46,583,308 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1349,178,503 - 49,190,055 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01350,466,576 - 50,478,127 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01347,732,661 - 47,744,208 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01351,958,023 - 51,971,431 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1351,958,834 - 51,972,777 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01357,009,427 - 57,023,148 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41348,094,119 - 48,105,707 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11348,108,161 - 48,119,750 (+)NCBI
Celera1346,897,613 - 46,908,578 (+)NCBICelera
Cytogenetic Map13q13NCBI
Ptpn7
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540638,232,589 - 38,250,195 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495540638,233,409 - 38,249,940 (-)NCBIChiLan1.0ChiLan1.0
PTPN7
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2147,220,186 - 47,234,828 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1147,184,863 - 47,199,505 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01177,744,963 - 177,759,611 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11182,047,418 - 182,061,889 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1182,049,084 - 182,061,151 (-)Ensemblpanpan1.1panPan2
PTPN7
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.17859,124 - 869,168 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl7859,214 - 869,183 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha7911,497 - 921,564 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.07867,172 - 877,245 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl7867,266 - 877,241 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.17855,561 - 865,624 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.07963,852 - 973,174 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.07987,836 - 997,900 (+)NCBIUU_Cfam_GSD_1.0
Ptpn7
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934473,146,132 - 73,158,479 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365672,382,931 - 2,391,542 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365672,381,519 - 2,392,562 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PTPN7
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1024,325,293 - 24,336,419 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11024,325,289 - 24,336,426 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21028,744,132 - 28,748,147 (-)NCBISscrofa10.2Sscrofa10.2susScr3
Ptpn7
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248078,575,371 - 8,593,552 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248078,575,414 - 8,593,063 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: XM_037985744   ⟹   XP_037841672
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366605528,023,740 - 28,038,993 (+)NCBI
RefSeq Acc Id: XM_037985745   ⟹   XP_037841673
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366605528,023,740 - 28,038,993 (+)NCBI
RefSeq Acc Id: XM_037985746   ⟹   XP_037841674
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366605528,023,857 - 28,038,993 (+)NCBI
RefSeq Acc Id: XM_037985747   ⟹   XP_037841675
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366605528,023,740 - 28,038,993 (+)NCBI
RefSeq Acc Id: XM_037985749   ⟹   XP_037841677
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366605528,023,104 - 28,038,993 (+)NCBI
RefSeq Acc Id: XM_037985750   ⟹   XP_037841678
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366605528,023,132 - 28,038,993 (+)NCBI
Reference Protein Sequences
RefSeq Acc Id: XP_037841677   ⟸   XM_037985749
- Peptide Label: isoform X5
- UniProtKB: A0A0D9RNP9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_037841678   ⟸   XM_037985750
- Peptide Label: isoform X6
RefSeq Acc Id: XP_037841672   ⟸   XM_037985744
- Peptide Label: isoform X1
RefSeq Acc Id: XP_037841673   ⟸   XM_037985745
- Peptide Label: isoform X2
RefSeq Acc Id: XP_037841675   ⟸   XM_037985747
- Peptide Label: isoform X4
RefSeq Acc Id: XP_037841674   ⟸   XM_037985746
- Peptide Label: isoform X3


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000014118 UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000012193.1 UniProtKB/TrEMBL
Gene3D-CATH Protein tyrosine phosphatase superfamily UniProtKB/TrEMBL
InterPro Prot-tyrosine_phosphatase-like UniProtKB/TrEMBL
  PTP_cat UniProtKB/TrEMBL
  Tyr_Pase_AS UniProtKB/TrEMBL
  Tyr_Pase_cat UniProtKB/TrEMBL
  Tyr_Pase_dom UniProtKB/TrEMBL
  Tyr_Pase_KIM-con UniProtKB/TrEMBL
NCBI Gene PTPN7 ENTREZGENE
PANTHER PROTEIN-TYROSINE-PHOSPHATASE UniProtKB/TrEMBL
  PROTEIN-TYROSINE-PHOSPHATASE UniProtKB/TrEMBL
Pfam Y_phosphatase UniProtKB/TrEMBL
PRINTS KIMPTPASE UniProtKB/TrEMBL
  PRTYPHPHTASE UniProtKB/TrEMBL
PROSITE TYR_PHOSPHATASE_1 UniProtKB/TrEMBL
  TYR_PHOSPHATASE_2 UniProtKB/TrEMBL
  TYR_PHOSPHATASE_PTP UniProtKB/TrEMBL
SMART PTPc UniProtKB/TrEMBL
  PTPc_motif UniProtKB/TrEMBL
Superfamily-SCOP (Phosphotyrosine protein) phosphatases II UniProtKB/TrEMBL
UniProt A0A0D9RNP9 ENTREZGENE, UniProtKB/TrEMBL