Ctsz (cathepsin Z) - Rat Genome Database

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Gene: Ctsz (cathepsin Z) Rattus norvegicus
Analyze
Symbol: Ctsz
Name: cathepsin Z
RGD ID: 708479
Description: Predicted to enable carboxypeptidase activity and cysteine-type endopeptidase activity. Predicted to be involved in epithelial tube branching involved in lung morphogenesis; negative regulation of plasminogen activation; and proteolysis involved in protein catabolic process. Located in several cellular components, including cell surface; extracellular space; and growth cone. Orthologous to human CTSZ (cathepsin Z); INTERACTS WITH 1-naphthyl isothiocyanate; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: cathepsin X; cathepsin Y; CATX; LOC252929
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83183,643,077 - 183,653,847 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl3183,643,077 - 183,657,012 (-)EnsemblGRCr8
mRatBN7.23163,224,875 - 163,235,645 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl3163,224,875 - 163,235,645 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx3167,023,616 - 167,034,386 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.03175,520,073 - 175,530,842 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.03173,264,462 - 173,275,232 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.03172,527,107 - 172,537,877 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3172,527,107 - 172,537,877 (-)Ensemblrn6Rnor6.0
Rnor_5.03178,574,619 - 178,585,389 (-)NCBIRnor_5.0Rnor_5.0rn5
Celera3162,398,362 - 162,409,134 (-)NCBICelera
Cytogenetic Map3q43NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,1-dichloroethene  (ISO)
1,2-dimethylhydrazine  (ISO)
1-naphthyl isothiocyanate  (EXP)
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (EXP,ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
3,3',5,5'-tetrabromobisphenol A  (EXP)
3,4-methylenedioxymethamphetamine  (ISO)
3-chloropropane-1,2-diol  (EXP)
4,4'-diaminodiphenylmethane  (EXP)
4,4'-sulfonyldiphenol  (EXP,ISO)
5-aza-2'-deoxycytidine  (ISO)
7,12-dimethyltetraphene  (ISO)
acetamide  (EXP)
acrylamide  (ISO)
aflatoxin B1  (EXP,ISO)
all-trans-retinoic acid  (ISO)
Aroclor 1254  (ISO)
benzo[a]pyrene  (ISO)
benzoates  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
bisphenol AF  (ISO)
Bisphenol B  (ISO)
bisphenol F  (EXP)
buspirone  (EXP)
Butylbenzyl phthalate  (EXP)
cadmium dichloride  (EXP)
carbon nanotube  (ISO)
copper atom  (ISO)
copper(0)  (ISO)
Cuprizon  (EXP)
cyclosporin A  (ISO)
dexamethasone  (ISO)
diazinon  (ISO)
dimethylarsinic acid  (EXP)
dorsomorphin  (ISO)
doxorubicin  (ISO)
fenamidone  (ISO)
formaldehyde  (ISO)
genistein  (ISO)
gentamycin  (EXP)
hydrogen peroxide  (ISO)
ivermectin  (ISO)
kainic acid  (ISO)
kojic acid  (ISO)
lead diacetate  (ISO)
lidocaine  (EXP)
methylmercury chloride  (ISO)
microcystin-LR  (ISO)
N-nitrosodimethylamine  (EXP)
nickel atom  (ISO)
nitrates  (ISO)
ozone  (ISO)
paracetamol  (ISO)
perfluorohexanesulfonic acid  (ISO)
pirinixic acid  (ISO)
rotenone  (ISO)
SB 431542  (ISO)
serpentine asbestos  (ISO)
silicon dioxide  (EXP)
sodium arsenite  (ISO)
sodium dichromate  (ISO)
Soman  (EXP)
sunitinib  (ISO)
tetrachloromethane  (ISO)
thioacetamide  (EXP)
thiram  (ISO)
titanium dioxide  (ISO)
trichostatin A  (ISO)
triphenyl phosphate  (ISO)
valproic acid  (ISO)
vorinostat  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cell cortex  (IDA,IEA,ISO)
cell surface  (IDA)
cytoplasmic vesicle  (IEA,ISO)
endoplasmic reticulum  (IEA,ISO)
extracellular region  (IEA)
extracellular space  (IBA,IDA,IEA,ISO)
growth cone  (IDA)
lysosome  (IBA,IEA,ISO)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Differential expression of Cathepsin S and X in the spinal cord of a rat neuropathic pain model. Leichsenring A, etal., BMC Neurosci. 2008 Aug 12;9:80.
3. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
4. Determination of the mRNA sequence of cathepsin Y, a cysteine endopeptidase from rat spleen, 1 and confirmation of its ubiquitous expression. Nakazono E, etal., Biol Chem 2002 Dec;383(12):1971-5.
5. Cathepsin X cleaves the C-terminal dipeptide of alpha- and gamma-enolase and impairs survival and neuritogenesis of neuronal cells. Obermajer N, etal., Int J Biochem Cell Biol. 2009 Aug-Sep;41(8-9):1685-96. doi: 10.1016/j.biocel.2009.02.019. Epub 2009 Mar 6.
6. GOA pipeline RGD automated data pipeline
7. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
8. Cathepsin Y (a novel thiol enzyme) produces kinin potentiating peptide from the component protein of rat plasma. Sakamoto E, etal., Immunopharmacology 1999 Dec;45(1-3):207-14.
Additional References at PubMed
PMID:12477932   PMID:17500053   PMID:20551380   PMID:23376485   PMID:23533145  


Genomics

Comparative Map Data
Ctsz
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83183,643,077 - 183,653,847 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl3183,643,077 - 183,657,012 (-)EnsemblGRCr8
mRatBN7.23163,224,875 - 163,235,645 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl3163,224,875 - 163,235,645 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx3167,023,616 - 167,034,386 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.03175,520,073 - 175,530,842 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.03173,264,462 - 173,275,232 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.03172,527,107 - 172,537,877 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3172,527,107 - 172,537,877 (-)Ensemblrn6Rnor6.0
Rnor_5.03178,574,619 - 178,585,389 (-)NCBIRnor_5.0Rnor_5.0rn5
Celera3162,398,362 - 162,409,134 (-)NCBICelera
Cytogenetic Map3q43NCBI
CTSZ
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382058,995,185 - 59,007,254 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2058,985,686 - 59,008,238 (-)Ensemblhg38GRCh38
GRCh372057,570,240 - 57,582,309 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362057,003,635 - 57,015,697 (-)NCBIBuild 36Build 36hg18NCBI36
Build 342057,003,634 - 57,015,680NCBI
Celera2054,310,657 - 54,322,736 (-)NCBICelera
Cytogenetic Map20q13.32NCBI
HuRef2054,357,148 - 54,369,230 (-)NCBIHuRef
CHM1_12057,471,631 - 57,483,697 (-)NCBICHM1_1
T2T-CHM13v2.02060,778,286 - 60,790,364 (-)NCBIT2T-CHM13v2.0
Ctsz
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm392174,269,287 - 174,280,832 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl2174,269,286 - 174,280,832 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm382174,427,494 - 174,439,039 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2174,427,493 - 174,439,039 (-)Ensemblmm10GRCm38
MGSCv372174,252,995 - 174,264,493 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv362174,070,433 - 174,081,931 (-)NCBIMGSCv36mm8
Celera2180,388,324 - 180,399,730 (-)NCBICelera
Cytogenetic Map2H4NCBI
cM Map297.94NCBI
Ctsz
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955445586,902 - 597,753 (+)Ensembl
ChiLan1.0NW_004955445586,901 - 597,753 (+)NCBIChiLan1.0ChiLan1.0
CTSZ
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22164,758,586 - 64,770,698 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12064,751,705 - 64,763,824 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02055,346,241 - 55,358,354 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12056,706,511 - 56,718,941 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2056,706,511 - 56,718,941 (-)EnsemblpanPan2panpan1.1
CTSZ
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12443,743,291 - 43,750,154 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2443,743,294 - 43,754,424 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha2442,989,417 - 42,996,868 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.02444,609,433 - 44,616,884 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2444,609,441 - 44,620,531 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12443,712,987 - 43,720,434 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02443,831,671 - 43,839,127 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02444,491,470 - 44,498,960 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Ctsz
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024408640181,815,540 - 181,824,209 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365301,482,012 - 1,490,736 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049365301,482,007 - 1,490,685 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CTSZ
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1759,138,621 - 59,149,377 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.11759,141,497 - 59,149,377 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21766,511,905 - 66,519,788 (-)NCBISscrofa10.2Sscrofa10.2susScr3
CTSZ
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.125,135,729 - 5,146,063 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl25,135,770 - 5,145,630 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366605053,186,955 - 53,197,273 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ctsz
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474125,280,916 - 25,301,800 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462474125,280,916 - 25,301,724 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Ctsz
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v15143,541,082 - 143,551,865 (+)NCBIRrattus_CSIRO_v1

miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:66
Count of miRNA genes:52
Interacting mature miRNAs:59
Transcripts:ENSRNOT00000072069
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
12879876Bw182Body weight QTL 1820.003body mass (VT:0001259)body weight (CMO:0000012)3141555229186555229Rat
2301411Bp320Blood pressure QTL 3200.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)3141555229186555229Rat
9589106Insul23Insulin level QTL 2313.860.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)3152055202189428310Rat
10755461Coatc16Coat color QTL 16coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)3142898802187898802Rat
12879872Cm97Cardiac mass QTL 970.001heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)3141555229186555229Rat
12879873Cm96Cardiac mass QTL 960.001heart mass (VT:0007028)heart wet weight to body weight ratio (CMO:0002408)3141555229186555229Rat
1559282Emca5Estrogen-induced mammary cancer QTL 53.9mammary gland integrity trait (VT:0010552)percentage of study population developing mammary tumors during a period of time (CMO:0000948)3145335553189428310Rat
1578653Vnigr3Vascular neointimal growth QTL 33.1artery morphology trait (VT:0002191)artery neointimal hyperplastic lesion area (CMO:0001414)3151075912189428310Rat
12879874Cm98Cardiac mass QTL 980.005heart right ventricle mass (VT:0007033)heart right ventricle weight to body weight ratio (CMO:0000914)3141555229186555229Rat
12879875Kidm64Kidney mass QTL 640.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)3141555229186555229Rat
1298068Bp167Blood pressure QTL 1670.004arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)3161492708189428310Rat
1582256Insul9Insulin level QTL 94.40.0016blood insulin amount (VT:0001560)absolute change in serum insulin level (CMO:0002038)3155759447189428310Rat
70216Cm14Cardiac mass QTL 142.1heart mass (VT:0007028)heart wet weight (CMO:0000069)351581665184004958Rat
1576306Schws3Schwannoma susceptibility QTL 30.001nervous system integrity trait (VT:0010566)percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)3139299381184299381Rat
1582248Insul7Insulin level QTL 73.90.0041blood insulin amount (VT:0001560)calculated serum insulin level (CMO:0000359)3155759447189428310Rat
1578666Vnigr1Vascular neointimal growth QTL 14.6artery morphology trait (VT:0002191)artery lumen area (CMO:0001409)3151075912189428310Rat
1300161Rf10Renal function QTL 103.57renal blood flow trait (VT:2000006)absolute change in renal vascular resistance (CMO:0001900)3181611379189428310Rat
8552791Vie2Viral induced encephalitis QTL 24.1brain integrity trait (VT:0010579)encephalitis incidence/prevalence measurement (CMO:0002361)3166376089189428310Rat
1578656Vnigr2Vascular neointimal growth QTL 24.2artery morphology trait (VT:0002191)lesioned artery residual lumen area (CMO:0001417)3151075912189428310Rat
1331726Bp208Blood pressure QTL 2083.129arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)3161799270187311134Rat
12879871Am7Aortic mass QTL 70.001aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)3141555229186555229Rat
631541Bp81Blood pressure QTL 814arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)3144575244189428310Rat
1582213Insul6Insulin level QTL 63.70.0009blood insulin amount (VT:0001560)calculated serum insulin level (CMO:0000359)3155759447189428310Rat
1598854Memor10Memory QTL 102exploratory behavior trait (VT:0010471)average horizontal distance between subject and target during voluntary locomotion in an experimental apparatus (CMO:0002674)3166376089189428310Rat

Markers in Region
RH130740  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.23163,224,497 - 163,224,698 (+)MAPPERmRatBN7.2
Rnor_6.03172,526,730 - 172,526,930NCBIRnor6.0
Rnor_5.03178,574,242 - 178,574,442UniSTSRnor5.0
Celera3162,397,985 - 162,398,185UniSTS
RH 3.4 Map31496.8UniSTS
AA818798  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.23163,225,050 - 163,225,230 (+)MAPPERmRatBN7.2
Rnor_6.03172,527,283 - 172,527,462NCBIRnor6.0
Rnor_5.03178,574,795 - 178,574,974UniSTSRnor5.0
Celera3162,398,538 - 162,398,717UniSTS
RH 3.4 Map31496.9UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 165 91 90 59 92 59 6 356 192 11 144 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000072069   ⟹   ENSRNOP00000066523
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl3183,643,077 - 183,657,012 (-)Ensembl
mRatBN7.2 Ensembl3163,224,875 - 163,235,645 (-)Ensembl
Rnor_6.0 Ensembl3172,527,107 - 172,537,877 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000110056   ⟹   ENSRNOP00000087446
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl3163,224,875 - 163,231,804 (-)Ensembl
RefSeq Acc Id: NM_183330   ⟹   NP_899159
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83183,643,077 - 183,653,847 (-)NCBI
mRatBN7.23163,224,875 - 163,235,645 (-)NCBI
Rnor_6.03172,527,107 - 172,537,877 (-)NCBI
Rnor_5.03178,574,619 - 178,585,389 (-)NCBI
Celera3162,398,362 - 162,409,134 (-)RGD
Sequence:
Protein Sequences
Protein RefSeqs NP_899159 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAH91110 (Get FASTA)   NCBI Sequence Viewer  
  BAA82844 (Get FASTA)   NCBI Sequence Viewer  
  EDL85083 (Get FASTA)   NCBI Sequence Viewer  
  EDL85084 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000066523
  ENSRNOP00000066523.1
GenBank Protein Q9R1T3 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_899159   ⟸   NM_183330
- Peptide Label: precursor
- UniProtKB: Q5BKD9 (UniProtKB/Swiss-Prot),   Q9R1T3 (UniProtKB/Swiss-Prot),   A6KL33 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000066523   ⟸   ENSRNOT00000072069
Ensembl Acc Id: ENSRNOP00000087446   ⟸   ENSRNOT00000110056
Protein Domains
Peptidase C1A papain C-terminal

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q9R1T3-F1-model_v2 AlphaFold Q9R1T3 1-306 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13692721
Promoter ID:EPDNEW_R3245
Type:initiation region
Name:Ctsz_1
Description:cathepsin Z
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.03172,537,883 - 172,537,943EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:708479 AgrOrtholog
BioCyc Gene G2FUF-46452 BioCyc
Ensembl Genes ENSRNOG00000050697 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000072069 ENTREZGENE
  ENSRNOT00000072069.2 UniProtKB/Swiss-Prot
Gene3D-CATH Cysteine proteinases UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:7379777 IMAGE-MGC_LOAD
InterPro Cathepsin_X UniProtKB/Swiss-Prot
  Papain-like_cys_pep_sf UniProtKB/Swiss-Prot
  Pept_asp_AS UniProtKB/Swiss-Prot
  Peptidase_C1A UniProtKB/Swiss-Prot
  Peptidase_C1A_C UniProtKB/Swiss-Prot
KEGG Report rno:252929 UniProtKB/Swiss-Prot
MGC_CLONE MGC:108536 IMAGE-MGC_LOAD
NCBI Gene 252929 ENTREZGENE
PANTHER CYSTEINE PROTEASE FAMILY C1-RELATED UniProtKB/Swiss-Prot
Pfam Peptidase_C1 UniProtKB/Swiss-Prot
PhenoGen Ctsz PhenoGen
PRINTS PAPAIN UniProtKB/Swiss-Prot
PROSITE THIOL_PROTEASE_ASN UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000050697 RatGTEx
SMART Pept_C1 UniProtKB/Swiss-Prot
Superfamily-SCOP SSF54001 UniProtKB/Swiss-Prot
UniProt A6KL32_RAT UniProtKB/TrEMBL
  A6KL33 ENTREZGENE, UniProtKB/TrEMBL
  CATZ_RAT UniProtKB/Swiss-Prot
  Q5BKD9 ENTREZGENE
  Q9R1T3 ENTREZGENE
UniProt Secondary Q5BKD9 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2005-07-08 Ctsz  cathepsin Z  LOC252929  cathepsin Y  Symbol and Name updated 1299863 APPROVED