Klhl17 (kelch-like family member 17) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Behavioral & Substance Use Disorder Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)
Gene: Klhl17 (kelch-like family member 17) Rattus norvegicus
Analyze
Symbol: Klhl17
Name: kelch-like family member 17
RGD ID: 708444
Description: Enables POZ domain binding activity; actin filament binding activity; and molecular adaptor activity. Involved in actin cytoskeleton organization and regulation protein catabolic process at postsynapse. Located in actin cytoskeleton; dendrite cytoplasm; and neuronal cell body. Is active in glutamatergic synapse and postsynapse. Orthologous to human KLHL17 (kelch like family member 17); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran; 2,6-dinitrotoluene.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: actinfilin; kelch-like 17; kelch-like 17 (Drosophila); kelch-like protein 17; LOC246757
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr85172,095,701 - 172,101,945 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl5172,094,940 - 172,101,195 (-)EnsemblGRCr8
mRatBN7.25166,813,482 - 166,819,949 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl5166,814,110 - 166,818,925 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx5169,515,574 - 169,521,068 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.05171,336,958 - 171,342,452 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.05171,299,519 - 171,305,012 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.05173,654,238 - 173,659,706 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5173,654,860 - 173,659,675 (-)Ensemblrn6Rnor6.0
Rnor_5.05177,128,278 - 177,134,602 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.45173,064,739 - 173,069,548 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera5165,015,955 - 165,020,764 (-)NCBICelera
RGSC_v3.15173,075,233 - 173,080,043 (-)NCBI
Cytogenetic Map5q36NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Interactions between CAP70 and actinfilin are important for integrity of actin cytoskeleton structures in neurons. Chen Y and Li M, Neuropharmacology. 2005 Dec;49(7):1026-41. Epub 2005 Jul 28.
2. Actinfilin, a Brain-specific Actin-binding Protein in Postsynaptic Density. Chen Y, etal., J Biol Chem 2002 Aug 23;277(34):30495-501.
3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
4. Autism-related KLHL17 and SYNPO act in concert to control activity-dependent dendritic spine enlargement and the spine apparatus. Hu HT, etal., PLoS Biol. 2023 Aug 31;21(8):e3002274. doi: 10.1371/journal.pbio.3002274. eCollection 2023 Aug.
5. GOA pipeline RGD automated data pipeline
6. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
7. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
8. Actinfilin is a Cul3 substrate adaptor, linking GluR6 kainate receptor subunits to the ubiquitin-proteasome pathway. Salinas GD, etal., J Biol Chem. 2006 Dec 29;281(52):40164-73. Epub 2006 Oct 24.
Additional References at PubMed
PMID:22664934  


Genomics

Comparative Map Data
Klhl17
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr85172,095,701 - 172,101,945 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl5172,094,940 - 172,101,195 (-)EnsemblGRCr8
mRatBN7.25166,813,482 - 166,819,949 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl5166,814,110 - 166,818,925 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx5169,515,574 - 169,521,068 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.05171,336,958 - 171,342,452 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.05171,299,519 - 171,305,012 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.05173,654,238 - 173,659,706 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5173,654,860 - 173,659,675 (-)Ensemblrn6Rnor6.0
Rnor_5.05177,128,278 - 177,134,602 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.45173,064,739 - 173,069,548 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera5165,015,955 - 165,020,764 (-)NCBICelera
RGSC_v3.15173,075,233 - 173,080,043 (-)NCBI
Cytogenetic Map5q36NCBI
KLHL17
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381960,584 - 965,719 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1960,576 - 965,719 (+)Ensemblhg38GRCh38
GRCh371895,964 - 901,099 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361885,830 - 890,958 (+)NCBIBuild 36Build 36hg18NCBI36
Build 341936,109 - 941,162NCBI
Celera11,690,578 - 1,695,031 (-)NCBICelera
Cytogenetic Map1p36.33NCBI
HuRef1166,390 - 170,737 (+)NCBIHuRef
CHM1_11883,012 - 888,029 (+)NCBICHM1_1
T2T-CHM13v2.01389,374 - 394,430 (+)NCBIT2T-CHM13v2.0
Klhl17
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm394156,313,501 - 156,319,314 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl4156,313,792 - 156,319,314 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm384156,229,044 - 156,234,857 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl4156,221,456 - 156,234,857 (-)Ensemblmm10GRCm38
MGSCv374155,603,153 - 155,608,966 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv364155,603,466 - 155,608,945 (-)NCBIMGSCv36mm8
Celera4158,485,528 - 158,491,396 (-)NCBICelera
Cytogenetic Map4E2NCBI
cM Map488.63NCBI
Klhl17
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554869,745,162 - 9,750,874 (-)Ensembl
ChiLan1.0NW_0049554869,745,162 - 9,750,874 (-)NCBIChiLan1.0ChiLan1.0
KLHL17
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21227,297,335 - 227,303,339 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11225,994,101 - 226,000,446 (-)NCBINHGRI_mPanPan1
PanPan1.11859,736 - 864,476 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1859,730 - 864,476 (+)EnsemblpanPan2panpan1.1
KLHL17
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1556,186,077 - 56,193,671 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl556,187,922 - 56,192,983 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha556,264,141 - 56,271,730 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0556,389,363 - 56,397,191 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl556,389,214 - 56,396,503 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1556,380,471 - 56,388,286 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0556,272,408 - 56,280,204 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0556,662,426 - 56,670,222 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Klhl17
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505827,379,695 - 27,385,239 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049367372,079,582 - 2,086,152 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049367372,080,699 - 2,086,252 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
KLHL17
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl663,322,184 - 63,328,259 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1663,320,898 - 63,328,093 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2657,898,263 - 57,901,884 (+)NCBISscrofa10.2Sscrofa10.2susScr3
KLHL17
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.120130,467,286 - 130,472,384 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl20130,467,261 - 130,471,904 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366605435,097,403 - 35,102,481 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Klhl17
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248188,546,137 - 8,550,603 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046248188,545,562 - 8,551,348 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Klhl17
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v114,434,525 - 4,439,982 (+)NCBIRrattus_CSIRO_v1

miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:92
Count of miRNA genes:82
Interacting mature miRNAs:86
Transcripts:ENSRNOT00000027547
Prediction methods:Microtar, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1576312Emca8Estrogen-induced mammary cancer QTL 84.1mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)555124766172190305Rat
10053720Scort26Serum corticosterone level QTL 262.060.0147blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)5130249266172190305Rat
1354583Despr3Despair related QTL34.980.0002locomotor behavior trait (VT:0001392)amount of time spent in voluntary immobility (CMO:0001043)5132930505172190305Rat
61444Strs2Sensitivity to stroke QTL 24.7cerebrum integrity trait (VT:0010549)post-insult time to onset of cerebrovascular lesion (CMO:0002343)5141212838172190305Rat
724525Bp147Blood pressure QTL 1474.30.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)5131708216172190305Rat
61452Ciaa5CIA Autoantibody QTL 53.5blood autoantibody amount (VT:0003725)calculated serum anti-rat type 2 collagen autoantibody titer (CMO:0001281)599905133172190305Rat
8552908Pigfal4Plasma insulin-like growth factor 1 level QTL 46.6blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)5133789363172190305Rat
1331803Rf32Renal function QTL 322.798kidney blood vessel physiology trait (VT:0100012)absolute change in renal vascular resistance (CMO:0001900)5134369199172190305Rat
7794791Mcs33Mammary carcinoma susceptibility QTL 331.93mammary gland integrity trait (VT:0010552)mammary tumor incidence/prevalence measurement (CMO:0000946)5136631198172190305Rat
1354631Swd2Spike wave discharge measurement QTL 23.640.0002brain electrophysiology trait (VT:0010557)brain total spike-and-wave discharge duration (CMO:0001740)5156396728172190305Rat
1598861Cm64Cardiac mass QTL 642.9heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)5133081618172190305Rat
1581505Rf54Renal function QTL 54kidney physiology trait (VT:0002136)kidney 20-HETE level (CMO:0001854)5133270647172190305Rat
1641920Colcs1Colorectal carcinoma susceptibility QTL 12.990.0055intestine integrity trait (VT:0010554)benign colorectal tumor surface area measurement (CMO:0001799)5160071170172129029Rat
2317753Glom24Glomerulus QTL 243.1kidney glomerulus integrity trait (VT:0010546)kidney sclerotic glomeruli count to total glomeruli count ratio (CMO:0001269)5141764300172190305Rat
1598819Bp292Blood pressure QTL 2924.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)5133081618172190305Rat
1331721Bp210Blood pressure QTL 2103.413arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)5148093485172129029Rat
8694169Bw148Body weight QTL 14850.001body mass (VT:0001259)body weight gain (CMO:0000420)5133789363172190305Rat
1581510Cm54Cardiac mass QTL 543.40.05heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)5125969677172190305Rat


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 162 91 90 59 92 59 6 356 192 11 141 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000027547   ⟹   ENSRNOP00000027547
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl5172,095,701 - 172,101,195 (-)Ensembl
mRatBN7.2 Ensembl5166,814,110 - 166,818,925 (-)Ensembl
Rnor_6.0 Ensembl5173,654,860 - 173,659,675 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000172287   ⟹   ENSRNOP00000106651
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl5172,095,396 - 172,100,828 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000172879   ⟹   ENSRNOP00000107567
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl5172,094,940 - 172,101,195 (-)Ensembl
RefSeq Acc Id: NM_145671   ⟹   NP_663704
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85172,095,701 - 172,101,195 (-)NCBI
mRatBN7.25166,813,482 - 166,818,976 (-)NCBI
Rnor_6.05173,654,860 - 173,659,669 (-)NCBI
Rnor_5.05177,128,278 - 177,134,602 (-)NCBI
RGSC_v3.45173,064,739 - 173,069,548 (-)RGD
Celera5165,015,955 - 165,020,764 (-)RGD
Sequence:
RefSeq Acc Id: XM_006239521   ⟹   XP_006239583
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85172,095,707 - 172,101,117 (-)NCBI
mRatBN7.25166,813,494 - 166,818,956 (-)NCBI
Rnor_6.05173,654,238 - 173,659,706 (-)NCBI
Rnor_5.05177,128,278 - 177,134,602 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008764336   ⟹   XP_008762558
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85172,095,707 - 172,101,117 (-)NCBI
mRatBN7.25166,813,494 - 166,818,956 (-)NCBI
Rnor_6.05173,654,238 - 173,659,706 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039109280   ⟹   XP_038965208
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85172,095,707 - 172,101,945 (-)NCBI
mRatBN7.25166,813,494 - 166,819,831 (-)NCBI
RefSeq Acc Id: XM_039109282   ⟹   XP_038965210
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85172,096,908 - 172,101,117 (-)NCBI
mRatBN7.25166,814,689 - 166,818,956 (-)NCBI
RefSeq Acc Id: XM_039109283   ⟹   XP_038965211
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85172,096,908 - 172,101,117 (-)NCBI
mRatBN7.25166,814,689 - 166,818,956 (-)NCBI
RefSeq Acc Id: XM_063287161   ⟹   XP_063143231
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85172,095,707 - 172,101,117 (-)NCBI
RefSeq Acc Id: NP_663704   ⟸   NM_145671
- UniProtKB: Q8K430 (UniProtKB/Swiss-Prot),   A6IUX0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006239583   ⟸   XM_006239521
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_008762558   ⟸   XM_008764336
- Peptide Label: isoform X2
- Sequence:
Ensembl Acc Id: ENSRNOP00000027547   ⟸   ENSRNOT00000027547
RefSeq Acc Id: XP_038965208   ⟸   XM_039109280
- Peptide Label: isoform X4
RefSeq Acc Id: XP_038965211   ⟸   XM_039109283
- Peptide Label: isoform X6
RefSeq Acc Id: XP_038965210   ⟸   XM_039109282
- Peptide Label: isoform X5
RefSeq Acc Id: XP_063143231   ⟸   XM_063287161
- Peptide Label: isoform X3
Ensembl Acc Id: ENSRNOP00000106651   ⟸   ENSRNOT00000172287
Ensembl Acc Id: ENSRNOP00000107567   ⟸   ENSRNOT00000172879
Protein Domains
BACK   BTB

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q8K430-F1-model_v2 AlphaFold Q8K430 1-640 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13694348
Promoter ID:EPDNEW_R4872
Type:single initiation site
Name:Klhl17_1
Description:kelch-like family member 17
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.05173,659,719 - 173,659,779EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:708444 AgrOrtholog
BioCyc Gene G2FUF-38856 BioCyc
Ensembl Genes ENSRNOG00000020302 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000027547 ENTREZGENE
  ENSRNOT00000027547.6 UniProtKB/Swiss-Prot
  ENSRNOT00000172287 ENTREZGENE
Gene3D-CATH 1.25.40.420 UniProtKB/Swiss-Prot
  2.120.10.80 UniProtKB/Swiss-Prot
  Potassium Channel Kv1.1, Chain A UniProtKB/Swiss-Prot
InterPro BACK UniProtKB/Swiss-Prot
  BTB-kelch_protein UniProtKB/Swiss-Prot
  BTB/POZ_dom UniProtKB/Swiss-Prot
  Gal_Oxase/kelch_b-propeller UniProtKB/Swiss-Prot
  Kelch-typ_b-propeller UniProtKB/Swiss-Prot
  Kelch_1 UniProtKB/Swiss-Prot
  SKP1/BTB/POZ_sf UniProtKB/Swiss-Prot
KEGG Report rno:246757 UniProtKB/Swiss-Prot
NCBI Gene 246757 ENTREZGENE
PANTHER KELCH PROTEIN UniProtKB/Swiss-Prot
  KELCH-LIKE PROTEIN 17 UniProtKB/Swiss-Prot
Pfam BACK UniProtKB/Swiss-Prot
  BTB UniProtKB/Swiss-Prot
  Kelch_1 UniProtKB/Swiss-Prot
PhenoGen Klhl17 PhenoGen
PIRSF Kelch-like_protein_gigaxonin UniProtKB/Swiss-Prot
PRINTS KELCHREPEAT UniProtKB/Swiss-Prot
PROSITE BTB UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000020302 RatGTEx
SMART BACK UniProtKB/Swiss-Prot
  BTB UniProtKB/Swiss-Prot
  Kelch UniProtKB/Swiss-Prot
Superfamily-SCOP SSF50965 UniProtKB/Swiss-Prot
  SSF54695 UniProtKB/Swiss-Prot
UniProt A0ABK0L8L9_RAT UniProtKB/TrEMBL
  A0ABK0LP69_RAT UniProtKB/TrEMBL
  A6IUX0 ENTREZGENE, UniProtKB/TrEMBL
  A6IUX1_RAT UniProtKB/TrEMBL
  A6IUX2_RAT UniProtKB/TrEMBL
  KLH17_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2013-02-06 Klhl17  kelch-like family member 17  Klhl17  kelch-like 17 (Drosophila)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-07-08 Klhl17  kelch-like 17 (Drosophila)  LOC246757  actinfilin  Symbol and Name updated 1299863 APPROVED

RGD Curation Notes
Note Type Note Reference
gene_expression expression is brain-specific 625502