Sox11 (SRY-box transcription factor 11) - Rat Genome Database

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Gene: Sox11 (SRY-box transcription factor 11) Rattus norvegicus
Analyze
Symbol: Sox11
Name: SRY-box transcription factor 11
RGD ID: 69351
Description: Enables DNA-binding transcription activator activity, RNA polymerase II-specific and transcription cis-regulatory region binding activity. Involved in kidney development; neurogenesis; and positive regulation of transcription by RNA polymerase II. Located in nucleus. Human ortholog(s) of this gene implicated in Coffin-Siris syndrome 9. Orthologous to human SOX11 (SRY-box transcription factor 11); INTERACTS WITH 6-propyl-2-thiouracil; alachlor; amitriptyline.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: SRY (sex determining region Y)-box 11; SRY box 11; SRY-box 11; SRY-box containing gene 11; transcription factor SOX-11
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8649,736,773 - 49,738,794 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl649,736,304 - 49,738,691 (-)EnsemblGRCr8
mRatBN7.2644,008,333 - 44,010,354 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl644,008,340 - 44,010,354 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx644,315,859 - 44,317,880 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0644,630,739 - 44,632,760 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0644,063,910 - 44,065,931 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0646,629,967 - 46,631,988 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl646,629,974 - 46,631,983 (-)Ensemblrn6Rnor6.0
Rnor_5.0655,343,067 - 55,345,088 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4645,141,366 - 45,143,387 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera643,252,857 - 43,254,878 (-)NCBICelera
RGSC_v3.1645,144,498 - 45,146,513 (-)NCBI
Cytogenetic Map6q16NCBI
JBrowse:




Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,2,4-trichloro-5-(2,5-dichlorophenyl)benzene  (ISO)
1,2-dichloroethane  (ISO)
17beta-estradiol  (ISO)
2,2',4,4',5,5'-hexachlorobiphenyl  (ISO)
2,2',5,5'-tetrachlorobiphenyl  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (ISO)
2,4,4'-trichlorobiphenyl  (ISO)
2-methylcholine  (ISO)
3,4-methylenedioxymethamphetamine  (ISO)
4,4'-sulfonyldiphenol  (ISO)
5-aza-2'-deoxycytidine  (ISO)
6-propyl-2-thiouracil  (EXP)
aflatoxin B1  (ISO)
alachlor  (EXP)
all-trans-retinoic acid  (ISO)
amitriptyline  (EXP)
aristolochic acid A  (ISO)
Aroclor 1254  (EXP)
arsane  (ISO)
arsenic atom  (ISO)
arsenite(3-)  (ISO)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
benzo[b]fluoranthene  (ISO)
bisphenol A  (EXP,ISO)
camptothecin  (ISO)
carbon nanotube  (ISO)
CGP 52608  (ISO)
chloroprene  (ISO)
chlorpyrifos  (EXP,ISO)
choline  (ISO)
cisplatin  (ISO)
clobetasol  (ISO)
clofibrate  (ISO)
Cuprizon  (EXP)
dexamethasone  (EXP,ISO)
dibutyl phthalate  (ISO)
dioxygen  (ISO)
dorsomorphin  (ISO)
entinostat  (ISO)
flavonoids  (EXP)
folic acid  (ISO)
genistein  (ISO)
gentamycin  (EXP)
glyphosate  (EXP)
graphite  (EXP)
hydroquinone  (ISO)
ketamine  (EXP)
L-ascorbic acid  (EXP)
L-methionine  (ISO)
linalool  (EXP)
methylphenidate  (ISO)
ozone  (ISO)
panobinostat  (ISO)
paracetamol  (EXP)
PCB138  (ISO)
phenylmercury acetate  (ISO)
pirinixic acid  (ISO)
progesterone  (ISO)
Ptaquiloside  (ISO)
resveratrol  (ISO)
SB 431542  (ISO)
sodium arsenite  (ISO)
Soman  (EXP)
streptozocin  (EXP)
temozolomide  (ISO)
testosterone  (EXP)
titanium dioxide  (ISO)
trichloroethene  (EXP)
trichostatin A  (ISO)
valproic acid  (ISO)
vorinostat  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
brain development  (IBA)
camera-type eye morphogenesis  (IBA)
cell differentiation  (IEA)
central nervous system development  (IEA)
closure of optic fissure  (IEA,ISO,ISS)
cornea development in camera-type eye  (IEA,ISO,ISS)
DNA-templated transcription  (IEA)
embryonic digestive tract morphogenesis  (IEA,ISO,ISS)
embryonic skeletal system morphogenesis  (IEA,ISO,ISS)
eyelid development in camera-type eye  (IEA,ISO,ISS)
glial cell development  (IEA,ISO)
glial cell proliferation  (IEA,ISO,ISS)
hard palate development  (IEA,ISO,ISS)
kidney development  (IEP)
lens morphogenesis in camera-type eye  (IEA,ISO,ISS)
lung morphogenesis  (IEA,ISO,ISS)
negative regulation of gene expression  (IEA,ISO,ISS)
negative regulation of glial cell proliferation  (IEA,ISO,ISS)
negative regulation of lymphocyte proliferation  (IEA,ISO)
negative regulation of transcription by RNA polymerase II  (IBA,IEA,ISO,ISS)
nervous system development  (IEA,ISO,ISS)
neuroepithelial cell differentiation  (IEA,ISO,ISS)
neuron differentiation  (IBA,IEA,ISO)
noradrenergic neuron differentiation  (IEA,IMP,ISO)
oligodendrocyte development  (IEP)
outflow tract morphogenesis  (IEA,ISO,ISS)
positive regulation of BMP signaling pathway  (IEA,ISO,ISS)
positive regulation of DNA-templated transcription  (IEA,ISO)
positive regulation of gene expression  (IEA,ISO,ISS)
positive regulation of hippo signaling  (IEA,ISO,ISS)
positive regulation of hormone secretion  (IEA,ISO,ISS)
positive regulation of lens epithelial cell proliferation  (IEA,ISO,ISS)
positive regulation of neurogenesis  (IEA,ISO,ISS)
positive regulation of neuron differentiation  (IEA,ISO,ISS)
positive regulation of ossification  (IEA,ISO,ISS)
positive regulation of osteoblast differentiation  (IEA,ISO,ISS)
positive regulation of stem cell proliferation  (IEA,ISO,ISS)
positive regulation of transcription by RNA polymerase II  (IBA,IEA,IMP,ISO,ISS)
regulation of transforming growth factor beta receptor signaling pathway  (IEA,ISO)
skeletal muscle cell differentiation  (ISO)
soft palate development  (IEA,ISO,ISS)
spinal cord development  (IEA,ISO,ISS)
sympathetic nervous system development  (IEA,ISO,ISS)
ventricular septum morphogenesis  (IEA,ISO,ISS)

Cellular Component
nucleoplasm  (IEA,ISO)
nucleus  (IBA,IDA,IEA,ISO)

References

References - curated
# Reference Title Reference Citation
1. The helix-loop-helix inhibitor of differentiation (ID) proteins induce post-mitotic terminally differentiated Sertoli cells to re-enter the cell cycle and proliferate. Chaudhary J, etal., Biol Reprod. 2005 May;72(5):1205-17. Epub 2005 Jan 12.
2. The three SoxC proteins--Sox4, Sox11 and Sox12--exhibit overlapping expression patterns and molecular properties. Dy P, etal., Nucleic Acids Res. 2008 May;36(9):3101-17. doi: 10.1093/nar/gkn162. Epub 2008 Apr 10.
3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
4. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
5. The Optimedin gene is a downstream target of Pax6. Grinchuk O, etal., J Biol Chem. 2005 Oct 21;280(42):35228-37. Epub 2005 Aug 22.
6. Cooperative function of POU proteins and SOX proteins in glial cells. Kuhlbrodt K, etal., J Biol Chem 1998 Jun 26;273(26):16050-7.
7. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
8. Mesenchymal-epithelial transition in the developing metanephric kidney: gene expression study by differential display. Plisov SY, etal., Genesis. 2000 May;27(1):22-31.
9. Sequential requirement of Sox4 and Sox11 during development of the sympathetic nervous system. Potzner MR, etal., Development. 2010 Mar;137(5):775-84. doi: 10.1242/dev.042101.
10. GOA pipeline RGD automated data pipeline
11. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
12. Fibroblast growth factor-inducible-14 is induced in axotomized neurons and promotes neurite outgrowth. Tanabe K, etal., J Neurosci. 2003 Oct 22;23(29):9675-86.
13. Tentative Sequence Identification Numbers Tentative Sequence Data IDs. TIGR Gene Index, Rat Data
14. Identification of novel domains within Sox-2 and Sox-11 involved in autoinhibition of DNA binding and partnership specificity. Wiebe MS, etal., J Biol Chem. 2003 May 16;278(20):17901-11. Epub 2003 Mar 10.
Additional References at PubMed
PMID:10574465   PMID:10606637   PMID:15254231   PMID:15456859   PMID:17934069   PMID:18261853   PMID:18423449   PMID:18505825   PMID:19490090   PMID:19808959   PMID:20596238   PMID:20624318  
PMID:20626275   PMID:20646169   PMID:20847309   PMID:21124928   PMID:21527504   PMID:25466891   PMID:31916393   PMID:32935389   PMID:38407972   PMID:39135278  


Genomics

Comparative Map Data
Sox11
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8649,736,773 - 49,738,794 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl649,736,304 - 49,738,691 (-)EnsemblGRCr8
mRatBN7.2644,008,333 - 44,010,354 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl644,008,340 - 44,010,354 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx644,315,859 - 44,317,880 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0644,630,739 - 44,632,760 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0644,063,910 - 44,065,931 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0646,629,967 - 46,631,988 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl646,629,974 - 46,631,983 (-)Ensemblrn6Rnor6.0
Rnor_5.0655,343,067 - 55,345,088 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4645,141,366 - 45,143,387 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera643,252,857 - 43,254,878 (-)NCBICelera
RGSC_v3.1645,144,498 - 45,146,513 (-)NCBI
Cytogenetic Map6q16NCBI
SOX11
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3825,692,384 - 5,701,385 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl25,692,384 - 5,701,385 (+)Ensemblhg38GRCh38
GRCh3725,832,516 - 5,841,517 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3625,750,250 - 5,758,968 (+)NCBIBuild 36Build 36hg18NCBI36
Build 3425,783,396 - 5,792,114NCBI
Celera25,748,512 - 5,756,851 (+)NCBICelera
Cytogenetic Map2p25.2NCBI
HuRef25,676,397 - 5,685,112 (+)NCBIHuRef
CHM1_125,762,093 - 5,770,810 (+)NCBICHM1_1
T2T-CHM13v2.025,713,811 - 5,722,812 (+)NCBIT2T-CHM13v2.0
Sox11
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391227,384,267 - 27,392,717 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1227,384,263 - 27,392,573 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm381227,334,268 - 27,342,718 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1227,334,264 - 27,342,574 (-)Ensemblmm10GRCm38
MGSCv371228,019,133 - 28,027,583 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361227,921,484 - 27,928,980 (-)NCBIMGSCv36mm8
Celera1228,811,290 - 28,819,758 (-)NCBICelera
Cytogenetic Map12A2NCBI
cM Map129.95NCBI
Sox11
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554872,679,145 - 2,680,521 (-)Ensembl
ChiLan1.0NW_0049554872,678,961 - 2,680,869 (-)NCBIChiLan1.0ChiLan1.0
SOX11
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v212120,808,899 - 120,820,381 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12A120,812,876 - 120,824,358 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02A5,699,738 - 5,711,210 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12A5,840,399 - 5,841,762 (+)NCBIPanPan1.1PanPan1.1panPan2
SOX11
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Dog10K_Boxer_Tasha173,570,850 - 3,572,822 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0173,680,433 - 3,682,409 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl173,680,517 - 3,682,010 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1173,573,068 - 3,575,034 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0173,576,503 - 3,578,454 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0173,580,950 - 3,582,922 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Sox11
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244050589,632,081 - 9,635,331 (-)NCBIHiC_Itri_2
SpeTri2.0NW_004937107203,120 - 207,185 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SOX11
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl3129,798,854 - 129,800,197 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.13129,797,438 - 129,800,568 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.23138,751,621 - 138,754,531 (-)NCBISscrofa10.2Sscrofa10.2susScr3
SOX11
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.114101,982,551 - 101,991,305 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl14101,989,895 - 101,991,220 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366604510,348,860 - 10,357,867 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Sox11
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248464,044,893 - 4,046,248 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046248464,043,010 - 4,046,660 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Sox11
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v1740,872,669 - 40,881,013 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Sox11
22 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:263
Count of miRNA genes:172
Interacting mature miRNAs:196
Transcripts:ENSRNOT00000045963
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
9590290Uminl2Urine mineral level QTL 23.960.001urine mineral amount (VT:0015086)urine electrolyte level (CMO:0000593)64451097489510974Rat
8693632Alc27Alcohol consumption QTL 272.20.791drinking behavior trait (VT:0001422)calculated ethanol drink intake rate (CMO:0001615)64005241156848866Rat
634318Bw118Body weight QTL 1183.55abdominal fat pad mass (VT:1000711)abdominal fat pad weight (CMO:0000088)63902865963457441Rat
10401812Kidm54Kidney mass QTL 54kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)62009763565097635Rat
634307Bp141Blood pressure QTL 1414arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)64095756485957564Rat
1331743Uae28Urinary albumin excretion QTL 284.5urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)64515378690153786Rat
8552910Pigfal5Plasma insulin-like growth factor 1 level QTL 54.3blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)62265388967653889Rat
10401800Kidm49Kidney mass QTL 49kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)62009763565097635Rat
1331779Rf38Renal function QTL 382.876kidney blood vessel physiology trait (VT:0100012)absolute change in renal vascular resistance (CMO:0001900)63118500276185002Rat
737827Hcar11Hepatocarcinoma resistance QTL 114.4liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)646050607116278722Rat
724513Uae14Urinary albumin excretion QTL 146.5urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)64604735391047353Rat
2293839Kiddil2Kidney dilation QTL 24.8kidney pelvis morphology trait (VT:0004194)hydronephrosis severity score (CMO:0001208)62661831486868070Rat
1576309Emca7Estrogen-induced mammary cancer QTL 74mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)620859430113082285Rat
9590140Scort4Serum corticosterone level QTL 414.490.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)64451097489510974Rat
2301964Bp323Blood pressure QTL 3234.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)6186868070Rat
9590306Scort18Serum corticosterone level QTL 182.880.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)64451097489510974Rat
1578665Bss16Bone structure and strength QTL 164.4femur morphology trait (VT:0000559)bone trabecular cross-sectional area (CMO:0002311)63332884178328841Rat
2293841Kiddil4Kidney dilation QTL 44.4kidney pelvis morphology trait (VT:0004194)hydronephrosis severity score (CMO:0001208)62661831486868070Rat
1641898Colcr4Colorectal carcinoma resistance QTL43.710.0007intestine integrity trait (VT:0010554)well differentiated malignant colorectal tumor surface area measurement (CMO:0002077)63093763275937632Rat
1578668Bmd14Bone mineral density QTL 143.8femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)63332884178328841Rat
6893340Cm77Cardiac mass QTL 770.260.57heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)63902865986867923Rat
70199Coreg1Compensatory renal growth QTL 111.8kidney mass (VT:0002707)compensatory renal growth score (CMO:0001894)61459947363457687Rat
2301972Bp325Blood pressure QTL 3254.8arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)61608937261967788Rat
1354664Slep2Serum leptin concentration QTL 24.49blood leptin amount (VT:0005667)serum leptin level (CMO:0000780)62228825767288257Rat
1300143Rf14Renal function QTL 142.92renal blood flow trait (VT:2000006)absolute change in renal blood flow rate (CMO:0001168)64016318385163183Rat

Markers in Region
RH140068  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2644,008,807 - 44,009,003 (+)MAPPERmRatBN7.2
Rnor_6.0646,630,442 - 46,630,637NCBIRnor6.0
Rnor_5.0655,343,542 - 55,343,737UniSTSRnor5.0
RGSC_v3.4645,141,841 - 45,142,036UniSTSRGSC3.4
Celera643,253,332 - 43,253,527UniSTS
RH 3.4 Map6263.2UniSTS
Cytogenetic Map6q16UniSTS
Sox11  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2644,007,548 - 44,008,282 (+)MAPPERmRatBN7.2
Rnor_6.0646,629,183 - 46,629,916NCBIRnor6.0
Rnor_5.0655,342,283 - 55,343,016UniSTSRnor5.0
RGSC_v3.4645,140,582 - 45,141,315UniSTSRGSC3.4
Celera643,252,073 - 43,252,806UniSTS
Cytogenetic Map6q16UniSTS
PMC85614P1  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2644,009,144 - 44,009,797 (+)MAPPERmRatBN7.2
Rnor_6.0646,630,779 - 46,631,431NCBIRnor6.0
Rnor_5.0655,343,879 - 55,344,531UniSTSRnor5.0
RGSC_v3.4645,142,178 - 45,142,830UniSTSRGSC3.4
Celera643,253,669 - 43,254,321UniSTS
Cytogenetic Map6q16UniSTS
Sox11  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2644,009,716 - 44,009,867 (+)MAPPERmRatBN7.2
Rnor_6.0646,631,351 - 46,631,501NCBIRnor6.0
Rnor_5.0655,344,451 - 55,344,601UniSTSRnor5.0
RGSC_v3.4645,142,750 - 45,142,900UniSTSRGSC3.4
Celera643,254,241 - 43,254,391UniSTS
Cytogenetic Map6q16UniSTS
UniSTS:547149  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2644,008,873 - 44,008,933 (+)MAPPERmRatBN7.2
Rnor_6.0646,630,508 - 46,630,567NCBIRnor6.0
Rnor_5.0655,343,608 - 55,343,667UniSTSRnor5.0
Celera643,253,398 - 43,253,457UniSTS
Cytogenetic Map6q16UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
11 11 59 133 63 64 35 33 35 3 251 116 4 117 81 86 29 8 8

Sequence


Ensembl Acc Id: ENSRNOT00000045963   ⟹   ENSRNOP00000040127
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl649,736,304 - 49,738,691 (-)Ensembl
mRatBN7.2 Ensembl644,008,340 - 44,010,354 (-)Ensembl
Rnor_6.0 Ensembl646,629,974 - 46,631,983 (-)Ensembl
RefSeq Acc Id: NM_053349   ⟹   NP_445801
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8649,736,773 - 49,738,794 (-)NCBI
mRatBN7.2644,008,333 - 44,010,354 (-)NCBI
Rnor_6.0646,629,967 - 46,631,988 (-)NCBI
Rnor_5.0655,343,067 - 55,345,088 (-)NCBI
RGSC_v3.4645,141,366 - 45,143,387 (-)RGD
Celera643,252,857 - 43,254,878 (-)RGD
Sequence:
Protein Sequences
Protein RefSeqs NP_445801 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein CAA06166 (Get FASTA)   NCBI Sequence Viewer  
  EDM03208 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000040127.3
GenBank Protein P0C1G9 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_445801   ⟸   NM_053349
- UniProtKB: P0C1G9 (UniProtKB/Swiss-Prot),   A6HB03 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000040127   ⟸   ENSRNOT00000045963
Protein Domains
HMG box

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P0C1G9-F1-model_v2 AlphaFold P0C1G9 1-395 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13694529
Promoter ID:EPDNEW_R5052
Type:single initiation site
Name:Sox11_1
Description:SRY box 11
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0646,631,983 - 46,632,043EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:69351 AgrOrtholog
BioCyc Gene G2FUF-37986 BioCyc
Ensembl Genes ENSRNOG00000030034 Ensembl, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000045963.5 UniProtKB/Swiss-Prot
Gene3D-CATH 1.10.30.10 UniProtKB/Swiss-Prot
InterPro HMG_box_dom UniProtKB/Swiss-Prot
  HMG_box_dom_sf UniProtKB/Swiss-Prot
  SOX-11/4 UniProtKB/Swiss-Prot
  SRY-related_HMG-box_TFs UniProtKB/Swiss-Prot
KEGG Report rno:84046 UniProtKB/Swiss-Prot
NCBI Gene 84046 ENTREZGENE
PANTHER PTHR10270:SF113 UniProtKB/Swiss-Prot
  SOX TRANSCRIPTION FACTOR UniProtKB/Swiss-Prot
Pfam HMG_box UniProtKB/Swiss-Prot
PhenoGen Sox11 PhenoGen
PIRSF SOX-12/11/4a UniProtKB/Swiss-Prot
PROSITE HMG_BOX_2 UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000030034 RatGTEx
SMART HMG UniProtKB/Swiss-Prot
Superfamily-SCOP SSF47095 UniProtKB/Swiss-Prot
TIGR TC221702
UniProt A6HB03 ENTREZGENE, UniProtKB/TrEMBL
  P0C1G9 ENTREZGENE, UniProtKB/Swiss-Prot
UniProt Secondary O35178 UniProtKB/Swiss-Prot
  O89036 UniProtKB/Swiss-Prot
  Q04889 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2019-08-05 Sox11  SRY-box transcription factor 11  Sox11  SRY box 11  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2015-11-13 Sox11  SRY box 11  Sox11  SRY (sex determining region Y)-box 11  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-09-18 Sox11  SRY (sex determining region Y)-box 11  Sox11  SRY-box containing gene 11  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2002-06-10 Sox11  SRY-box containing gene 11      Name updated 70584 APPROVED

RGD Curation Notes
Note Type Note Reference