Ruvbl1 Rat Gene (RuvB-like 1 (E. coli))

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Keyword

Gene:
Ruvbl1 ( Rattus norvegicus )
RuvB-like 1 (E. coli)
Description: nuclear DNA helicase that binds TBP; involved in recombination and transcription
Synonyms: Pontin52; NMP238; RuvB-like protein 1; Tip49a;  (details...)
ArrayIDs: 5887086; 5889192; 1370386_at; 6103242; 5641214; rc_AI043861_at; 6699299; 5742025; 6420235; 5863621; 5699596; 6420245; A_42_P699162; 6561234; AB002406_at; 6302574; 5747506; GE13017; 6669555; 6164445; 5920643; 6330698; A_44_P218014; 6012501; 5678120; 6485705;  (details...)
Gene Type: protein-coding

Additional Data

Homologs
Homo sapiens: RUVBL1     See the Human gene in context in:     UCSC     NCBI MapViewer

Mus musculus: Ruvbl1     See the Mouse gene in context in:     UCSC     NCBI MapViewer

Comparative Map Data
Species Symbol Map Name Chr. Position
Rattus norvegicus Ruvbl1 genome assembly 3.1 4 122801337 - 122836249
Rat Celera Assembly 4 109888321 - 109923233
RGSC genome assembly v3.4 4 122556857 - 122591769
Cytogenetic 4 q34
Mus musculus Ruvbl1 Mouse genome assembly build 36.1 6 88415417 - 88447560
Cytogenetic 6 6 D1
Homo sapiens RUVBL1 human genome assembly 3 129282500 - 129325340
Human genome assembly build 36.2 3 129282493 - 129325332
Cytogenetic 3 q21

View comparative maps:      NCBI MapViewer

Genome
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Annotation
Molecular Function

Note Reference

DNA helicase 729809

binds to the TATA-binding protein (TBP), also binds plasminogen 68301

Gene Ontology

ATPase activity,  protein binding,  nucleotide binding ... (details...)
Biological Process

Note Reference

plays a role in recombination and transcription 729809

enhances plasminogen activation 68301

Gene Ontology

cell division,  histone H2A acetylation,  regulation of growth ... (details...)
Cellular Component

Note Reference

localizes to liver nuclear extracts 68301

Gene Ontology

nucleus,  NuA4 histone acetyltransferase complex,  ribonucleoprotein complex (details...)

External Links
Databases
DATABASE ID SOURCE
SMART: AAA IPI
UNIPARC: UPI0000029B3E IPI
KEGG Report: rno:65137 ENTREZGENE
HomoloGene Group ID: 37839 ENTREZGENE
Germonline: 68373
Pfam: AAA IPI
Pfam: TIP49 IPI
KEGG Pathway: 04310 ENTREZGENE
InterPro: ATPase_AAA+_core. IPI
InterPro: TIP49_C. IPI
InterPro: ATPase_AAA_core. IPI
IPI: IPI00212268 IPI
Ensembl Protein: ENSRNOP00000018339 IPI
IMAGE_CLONE: IMAGE:7304521 IMAGE-MGC_LOAD
IMAGE_CLONE: IMAGE:7104777 IMAGE-MGC_LOAD
Entrez Gene: Ruvbl1 ENTREZGENE
MGC_CLONE: MGC:91456 IMAGE-MGC_LOAD
MGC_CLONE: MGC:105307 IMAGE-MGC_LOAD
TIGR: TC207355
UniProt: RUVB1_RAT IPI
Ensembl Genes: ENSRNOG00000013195 IPI
Sequences
Nucleotide: AB001581 Get FASTA Search GEO Profiles
Nucleotide: AB002406 Get FASTA Search GEO Profiles
Nucleotide: CH473957 Get FASTA Search GEO Profiles
Nucleotide: BC072511 Get FASTA Search GEO Profiles
Nucleotide: NM_147177 Get FASTA Search GEO Profiles
Nucleotide: BC086531 Get FASTA Search GEO Profiles
(View all 6 Nucleotide Accessions)
Protein: AAH72511 Get FASTA
Protein: NP_671706 Get FASTA
Protein: BAA20875 Get FASTA
Protein: EDL91312 Get FASTA
Protein: P60123 Get FASTA
Protein: AAH86531 Get FASTA
Protein: BAA76313 Get FASTA
(View all 7 Protein Accessions)
Clusters
UniGene: 86410

References
Curated References
9 references in RGD related to Ruvbl1

Other References
6 other references at PubMed related to Ruvbl1

Database Information
RGD ID 68373
History

Date Current Symbol Current Name Previous Symbol Previous name Status Description Reference

30-OCT-08: Ruvbl1 RuvB-like 1 (E. coli) Ruvbl1 RuvB-like protein 1 APPROVED Nomenclature updated to reflect human and mouse nomenclature 1299863

10-JUN-02: Ruvbl1 ruvB-like protein 1 APPROVED Symbol and Name status set to approved 70586