Bex5l1 (brain expressed X-linked 5 like 1) - Rat Genome Database

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Gene: Bex5l1 (brain expressed X-linked 5 like 1) Rattus norvegicus
Analyze
Symbol: Bex5l1 (Ensembl: LOC100912195)
Name: brain expressed X-linked 5 like 1 (Ensembl:protein BEX1-like)
RGD ID: 6488322
Description: Orthologous to human BEX5 (brain expressed X-linked 5); INTERACTS WITH acrylamide (ortholog); aflatoxin B1 (ortholog); belinostat (ortholog).
Type: protein-coding
RefSeq Status: MODEL
Previously known as: LOC100361937; LOC100912195; protein BEX1-like
RGD Orthologs
Human
Bonobo
Dog
Squirrel
Pig
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81119,181,370 - 119,202,904 (-)NCBIGRCr8GRCr8GRCr8
mRatBN7.21110,047,861 - 110,051,812 (-)NCBImRatBN7.2mRatBN7.2
Rnor_6.01116,565,779 - 116,567,283 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1116,565,790 - 116,567,189 (-)Ensemblrn6Rnor6.0
Rnor_5.01117,724,191 - 117,725,657 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41110,708,014 - 110,708,403 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Cytogenetic Map1q22NCBI
JBrowse:




Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytoplasm  (IEA)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:12911636   PMID:20731761   PMID:23376485  


Genomics

Comparative Map Data
Bex5l1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81119,181,370 - 119,202,904 (-)NCBIGRCr8GRCr8GRCr8
mRatBN7.21110,047,861 - 110,051,812 (-)NCBImRatBN7.2mRatBN7.2
Rnor_6.01116,565,779 - 116,567,283 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1116,565,790 - 116,567,189 (-)Ensemblrn6Rnor6.0
Rnor_5.01117,724,191 - 117,725,657 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41110,708,014 - 110,708,403 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Cytogenetic Map1q22NCBI
BEX5
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38X102,153,712 - 102,155,977 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 EnsemblX102,153,464 - 102,156,017 (-)Ensemblhg38GRCh38
GRCh37X101,408,684 - 101,410,949 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36X101,295,340 - 101,297,685 (-)NCBIBuild 36Build 36hg18NCBI36
CeleraX101,929,239 - 101,931,548 (-)NCBICelera
Cytogenetic MapXq22.1NCBI
HuRefX91,216,777 - 91,219,086 (-)NCBIHuRef
CHM1_1X101,302,593 - 101,304,902 (-)NCBICHM1_1
T2T-CHM13v2.0X100,598,297 - 100,600,564 (-)NCBIT2T-CHM13v2.0
BEX5
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2X101,758,145 - 101,760,446 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1X101,761,750 - 101,764,050 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0X91,361,030 - 91,363,335 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1X101,488,813 - 101,491,117 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 EnsemblX101,489,036 - 101,489,371 (-)EnsemblpanPan2panpan1.1
BEX5
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1X75,930,148 - 75,932,618 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 EnsemblX75,930,633 - 75,930,971 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_TashaX62,295,892 - 62,298,114 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0X77,352,165 - 77,354,387 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 EnsemblX77,350,158 - 77,354,311 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1X74,922,191 - 74,924,413 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0X76,565,330 - 76,568,459 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0X76,328,317 - 76,331,446 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Bex5
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2X61,938,894 - 61,941,173 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004937070148,400 - 150,529 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_004937070148,270 - 150,535 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
BEX5
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 EnsemblX83,607,375 - 83,609,794 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1X83,607,366 - 83,609,797 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2X97,469,217 - 97,471,660 (-)NCBISscrofa10.2Sscrofa10.2susScr3

Variants

.
Variants in Bex5l1
217 total Variants

QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
631496Bp97Blood pressure QTL 973.08arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1115183611176289080Rat
1582234Gluco18Glucose level QTL 183.40.0003blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)187889942132889942Rat
1358359Sradr1Stress Responsive Adrenal Weight QTL 14.74adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)139728272132889942Rat
634314Niddm44Non-insulin dependent diabetes mellitus QTL 44blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)151941022208479811Rat
1331793Bp200Blood pressure QTL 2003.71601arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1102780511182384005Rat
1578654Bss10Bone structure and strength QTL 104femur morphology trait (VT:0000559)femoral neck cortical cross-sectional area (CMO:0001702)151940904168768703Rat
1554320Bmd1Bone mineral density QTL 112.20.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)1101228864146228864Rat
1354591Cm36Cardiac mass QTL 364.1heart left ventricle mass (VT:0007031)calculated heart weight (CMO:0000073)1111949780210707719Rat
1331800Scl25Serum cholesterol level QTL 253.013blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)187785026142582336Rat
7421628Bp361Blood pressure QTL 3610.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)183019780128019780Rat
9590300Scort16Serum corticosterone level QTL 164.390.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)1112521556157521556Rat
70225Bp58Blood pressure QTL 583.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)134184556172281316Rat
2298545Neuinf8Neuroinflammation QTL 84.6nervous system integrity trait (VT:0010566)spinal cord beta-2 microglobulin mRNA level (CMO:0002125)166009857160501508Rat
10059597Bp377Blood pressure QTL 3773.420.025arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)134565911208798288Rat
631519Pia11Pristane induced arthritis QTL 115.3joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)193903998191260518Rat
1302788Scl19Serum cholesterol QTL 194.60.001blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)166400974132889942Rat
61399Tcat1Tongue tumor resistance QTL 13.3tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 5 mm (CMO:0001879)1108680016153680016Rat
2313083Bmd74Bone mineral density QTL 7440.0001tibia mineral mass (VT:1000283)total volumetric bone mineral density (CMO:0001728)191302413136302413Rat
631569Bp93Blood pressure QTL 930.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1115183611131244255Rat
2313402Anxrr24Anxiety related response QTL 24aggression-related behavior trait (VT:0015014)tameness/aggressiveness composite score (CMO:0002136)151511344153680016Rat
724567Tcas6Tongue tumor susceptibility QTL 66.85tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)1102359314153680016Rat
724521Uae1Urinary albumin excretion QTL 13.80.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)199645382182701046Rat
1358902Bw47Body weight QTL 471.67body mass (VT:0001259)body weight (CMO:0000012)199645382221502378Rat
1354615Cm32Cardiac mass QTL 325.2heart left ventricle mass (VT:0007031)heart left ventricle wet weight (CMO:0000071)1111949780210707719Rat
1358192Ept13Estrogen-induced pituitary tumorigenesis QTL 133.4pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)186622262131622262Rat
8655649Arrd1Age-related retinal degeneration QTL 14.89retinal layer morphology trait (VT:0003727)percentage of study population developing retinopathy during a period of time (CMO:0002453)1109493780193400781Rat
8694370Bw154Body weight QTL 1548.910.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)1112521556157521556Rat
2317833Alcrsp19Alcohol response QTL 1912.40.001response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)1110389869155389869Rat
731168Bp154Blood pressure QTL 1543.4arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1103779152223964440Rat
1354623Rf46Renal function QTL 463.8blood creatinine amount (VT:0005328)plasma creatinine level (CMO:0000537)1111949780160574007Rat
631205Bp196Blood pressure QTL 19640.0001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)198879955208479939Rat
738022Anxrr13Anxiety related response QTL 134.60.00039locomotor behavior trait (VT:0001392)measurement of voluntary locomotion into, out of, or within a discrete space in an open field apparatus (CMO:0001514)192683681137683681Rat
10054135Gmadr2Adrenal mass QTL 21.970.0129adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)186993904131993904Rat
1641897Alcrsp1Alcohol response QTL 1response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)1110389869155389869Rat
7411712Strs4Sensitivity to stroke QTL 48.7cerebrum integrity trait (VT:0010549)percentage of study population developing cerebrovascular lesions during a period of time (CMO:0000932)187558587132558587Rat
1331749Hrtrt11Heart rate QTL 112.973heart pumping trait (VT:2000009)heart rate (CMO:0000002)192683681137683681Rat
737977Bp160Blood pressure QTL 1600.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)197582336142582336Rat
1331751Bp199Blood pressure QTL 1993.60022arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)1116099376191260518Rat
2293142Bp314Blood pressure QTL 314arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1101594089146594089Rat
61433Cia2Collagen induced arthritis QTL 25joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1100345976145345976Rat
724529Cm16Cardiac mass QTL 162.7heart mass (VT:0007028)calculated heart weight (CMO:0000073)196717367160111531Rat
61370Mcs3Mammary carcinoma susceptibility QTL 32.15mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)1111404407142582336Rat
1354606Bp246Blood pressure QTL 2463.6arterial blood pressure trait (VT:2000000)pulse pressure (CMO:0000292)1111949780228180370Rat

Markers in Region
RH134506  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2X99,219,051 - 99,219,259 (+)MAPPERmRatBN7.2
Rnor_6.0X106,763,333 - 106,763,533NCBIRnor6.0
Rnor_6.01116,565,827 - 116,566,034NCBIRnor6.0
Rnor_5.01117,724,239 - 117,724,446UniSTSRnor5.0
RGSC_v3.4X123,527,774 - 123,527,981UniSTSRGSC3.4
CeleraX99,926,796 - 99,927,003UniSTS
Cytogenetic MapXq35UniSTS
RH126864  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2X99,219,015 - 99,219,251 (+)MAPPERmRatBN7.2
Rnor_6.01116,565,791 - 116,566,026NCBIRnor6.0
Rnor_5.01117,724,203 - 117,724,438UniSTSRnor5.0
Rnor_5.0X106,565,167 - 106,565,438UniSTSRnor5.0
Cytogenetic MapXq35UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
9 11 49 113 91 90 59 25 59 6 218 97 4 93 45 60 31 10 10

Sequence


Ensembl Acc Id: ENSRNOT00000048996   ⟹   ENSRNOP00000039471
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 EnsemblX99,219,014 - 99,220,958 (-)Ensembl
Rnor_6.0 Ensembl1116,565,790 - 116,567,189 (-)Ensembl
RefSeq Acc Id: XM_063278646   ⟹   XP_063134716
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81119,181,370 - 119,202,904 (-)NCBI
Protein Sequences
Protein RefSeqs XP_063134716 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000112742
  ENSRNOP00000112742.1
Ensembl Acc Id: ENSRNOP00000039471   ⟸   ENSRNOT00000048996
RefSeq Acc Id: XP_063134716   ⟸   XM_063278646

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-A0A096MIT8-F1-model_v2 AlphaFold A0A096MIT8 1-128 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:6488322 AgrOrtholog
BioCyc Gene G2FUF-59423 BioCyc
Ensembl Genes ENSRNOG00000033844 Ensembl
  ENSRNOG00000082512 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000157037 ENTREZGENE
  ENSRNOT00000157037.1 UniProtKB/TrEMBL
NCBI Gene LOC100912195 ENTREZGENE
PhenoGen Bex5l1 PhenoGen
RatGTEx ENSRNOG00000033844 RatGTEx
  ENSRNOG00000082512 RatGTEx
UniProt A0ABK0M8W2_RAT UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2025-05-12 Bex5l1  brain expressed X-linked 5 like 1  LOC100912195  protein BEX1-like  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2015-07-29 LOC100912195  protein BEX1-like  LOC100361937  protein BEX1-like  Data merged from RGD:2319143 737654 PROVISIONAL
2012-07-05 LOC100912195  protein BEX1-like      Symbol and Name status set to provisional 70820 PROVISIONAL
2010-05-05 LOC100361937  protein BEX1-like      Symbol and Name status set to provisional 70820 PROVISIONAL