Gene:	Fzd6 ( Rattus norvegicus ) frizzled homolog 6 (Drosophila)
Description:	human homolog is a Wnt signaling receptor that may act as a negative regulator of the beta-catenin signaling cascade
ArrayIDs:	A_44_P334991; 6095880; 5980783; 1388994_at; 6502942; 5876031; 5628998; 6464720; 5949070; 6336912; 6015072; rc_AA900855_at; 6082864;  (details...)
Gene Type:	protein-coding
Additional Data
Homologs
Homo sapiens: FZD6     See the Human gene in context in:     UCSC     NCBI MapViewer
Mus musculus: Fzd6     See the Mouse gene in context in:     UCSC     NCBI MapViewer
Comparative Map Data Species Symbol Map Name Chr. Position Rattus norvegicus Fzd6 Rat Celera Assembly 7 67112475 - 67142071     RGSC genome assembly v3.4 7 74563328 - 74592928     Cytogenetic 7 q22     genome assembly 3.1 7 74608138 - 74610532 Mus musculus Fzd6 Mouse genome assembly build 36.1 15 38837898 - 38869738     Cytogenetic 15 15 B3.1 Homo sapiens FZD6 human genome assembly 8 104380275 - 104414268     Human genome assembly build 36.2 8 104380276 - 104414270     Cytogenetic 8 q22.3-q23.1   View comparative maps:      NCBI MapViewer
Genome
View:
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Annotation
Molecular Function	Gene Ontology non-G-protein coupled 7TM receptor activity,  molecular_function (details...)
Biological Process	Gene Ontology inner ear morphogenesis,  biological_process,  neural tube closure ...  (details...)
Cellular Component	Gene Ontology membrane,  apical part of cell,  cellular_component ...  (details...)
Pathway	Ontology Wnt signaling pathway,  the planar cell polarity Wnt signaling pathway (details...)
External Links
Databases	DATABASE ID SOURCE SMART: FRI IPI PROSITE: G_PROTEIN_RECEP_F2_4 IPI PROSITE: FZ IPI UNIPARC: UPI0000503E8D IPI KEGG Report: rno:282581 ENTREZGENE HomoloGene Group ID: 2617 ENTREZGENE Germonline: 628816 Pfam: Fz IPI Pfam: Frizzled IPI KEGG Pathway: 05217 ENTREZGENE KEGG Pathway: 04916 ENTREZGENE KEGG Pathway: 05200 ENTREZGENE KEGG Pathway: 05210 ENTREZGENE KEGG Pathway: 04310 ENTREZGENE InterPro: Frizzled-like_dom. IPI InterPro: Frizzled_Cys-rich. IPI InterPro: Frizzled_dom_subgr. IPI InterPro: Frizzled_related. IPI InterPro: GPCR_2-like. IPI InterPro: Frizzled. IPI IPI: IPI00366243 IPI Ensembl Protein: ENSRNOP00000006195 IPI Gene3D-CATH: Frizzled_Cys-rich IPI Entrez Gene: Fzd6 ENTREZGENE UniProt: Q8CFA9_RAT IPI Ensembl Genes: ENSRNOG00000004660 IPI Superfamily-SCOP: Frizzled_Cys-rich IPI PANTHER: Fz_related IPI PRINTS: FRIZZLED. IPI
Sequences	Nucleotide: XM_343230 Get FASTA Search GEO Profiles Nucleotide: XM_001061748 Get FASTA Search GEO Profiles Nucleotide: NM_001130536 Get FASTA Search GEO Profiles Nucleotide: CH473950 Get FASTA Search GEO Profiles Nucleotide: AF481948 Get FASTA Search GEO Profiles (View all 5 Nucleotide Accessions) Protein: XP_343231 Get FASTA Protein: XP_001061748 Get FASTA Protein: NP_001124008 Get FASTA Protein: EDM16356 Get FASTA Protein: AAN51981 Get FASTA Protein: Q8CFA9 Get FASTA (View all 6 Protein Accessions)
Clusters	UniGene: 2740
References
Curated References	7 references in RGD related to Fzd6
Other References	2 other references at PubMed related to Fzd6
Database Information
RGD ID	628816
History	Date Current Symbol Current Name Previous Symbol Previous name Status Description Reference 20-JAN-05: Fzd6 frizzled homolog 6 (Drosophila) APPROVED Symbol and Name status set to approved 1299863 27-FEB-03: Fzd6 frizzled homolog 6 (Drosophila) PROVISIONAL Symbol and Name status set to provisional 70820