Gene:	Fzd3 ( Rattus norvegicus ) frizzled homolog 3 (Drosophila)
Description:	human homolog is a Wnt receptor involved in proliferation of primary endothelial cells
ArrayIDs:	1385636_at; rc_AI029226_at;  (details...)
Gene Type:	protein-coding
Additional Data
Homologs
Comparative Map Data Species Symbol Map Name Chr. Position Rattus norvegicus Fzd3 Rat Celera Assembly 15 39096287 - 39163152   View comparative maps:
Genome
View:
Annotation
Molecular Function	Gene Ontology non-G-protein coupled 7TM receptor activity,  G-protein coupled receptor activity (details...)
Biological Process	Gene Ontology multicellular organismal development,  G-protein coupled receptor protein signaling pathway,  response to drug ...  (details...)
Cellular Component	Gene Ontology membrane,  integral to membrane (details...)
Disease	Ontology Schizophrenia,  Williams Syndrome (details...)
Pathway	Ontology Wnt signaling pathway,  the planar cell polarity Wnt signaling pathway (details...)
External Links
Databases	DATABASE ID SOURCE SMART: FRI IPI PROSITE: FZ IPI PROSITE: G_PROTEIN_RECEP_F2_4 IPI UNIPARC: UPI00000E8B74 IPI KEGG Report: rno:266715 ENTREZGENE Germonline: 628814 Pfam: Fz IPI Pfam: Frizzled IPI KEGG Pathway: 04310 ENTREZGENE KEGG Pathway: 05210 ENTREZGENE KEGG Pathway: 05217 ENTREZGENE KEGG Pathway: 04916 ENTREZGENE InterPro: Frizzled_dom_subgr. IPI InterPro: Frizzled_related. IPI InterPro: GPCR_2-like. IPI InterPro: Frizzled_Cys-rich. IPI InterPro: Frizzled. IPI InterPro: Frizzled-like_dom. IPI IPI: IPI00194675 IPI Gene3D-CATH: Frizzled_Cys-rich IPI Entrez Gene: Fzd3 ENTREZGENE UniProt: Q8CFB0_RAT IPI UniProt: Q8CJC4_RAT IPI Superfamily-SCOP: Frizzled_Cys-rich IPI PANTHER: Fz_related IPI PRINTS: FRIZZLED. IPI
Sequences	Nucleotide: CH474023 Get FASTA Search GEO Profiles Nucleotide: AF323956 Get FASTA Search GEO Profiles Nucleotide: NM_153474 Get FASTA Search GEO Profiles Nucleotide: AF481947 Get FASTA Search GEO Profiles (View all 4 Nucleotide Accessions) Protein: AAN51982 Get FASTA Protein: AAN14442 Get FASTA Protein: NP_703204 Get FASTA Protein: EDL85352 Get FASTA Protein: Q8CJC4 Get FASTA Protein: Q8CFB0 Get FASTA Protein: EDL85351 Get FASTA (View all 7 Protein Accessions)
Clusters	UniGene: 178695
References
Curated References	13 references in RGD related to Fzd3
Other References	6 other references at PubMed related to Fzd3
Database Information
RGD ID	628814
History	Date Current Symbol Current Name Previous Symbol Previous name Status Description Reference 20-JAN-05: Fzd3 frizzled homolog 3 (Drosophila) APPROVED Symbol and Name status set to approved 1299863 27-FEB-03: Fzd3 frizzled homolog 3 (Drosophila) PROVISIONAL Symbol and Name status set to provisional 70820