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Gene: Aip (AHR interacting HSP90 co-chaperone) Rattus norvegicus

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Symbol:

Aip

Name:

AHR interacting HSP90 co-chaperone (Ensembl:aryl-hydrocarbon receptor-interacting protein)

RGD ID:

628619

Description:

Enables enzyme binding activity. Involved in protein kinase A signaling. Predicted to be located in cytosol and plasma membrane. Predicted to be part of aryl hydrocarbon receptor complex. Human ortholog(s) of this gene implicated in pituitary adenoma 1. Orthologous to human AIP (aryl hydrocarbon receptor interacting protein); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4,6-trinitrotoluene; 3-chloropropane-1,2-diol.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

AH receptor-interacting protein; aryl-hydrocarbon receptor-interacting protein; HBV-X associated protein; immunophilin XAP2; XAP2

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	AIP (AHR interacting HSP90 co-chaperone)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, PhylomeDB, Treefam
Mus musculus (house mouse):	Aip (aryl-hydrocarbon receptor-interacting protein)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Aip (AHR interacting HSP90 co-chaperone)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	AIP (AHR interacting HSP90 co-chaperone)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	AIP (aryl hydrocarbon receptor interacting protein)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Aip (AHR interacting HSP90 co-chaperone)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	AIP (aryl hydrocarbon receptor interacting protein)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	AIP (AHR interacting HSP90 co-chaperone)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Aip (AHR interacting HSP90 co-chaperone)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus rattus (black rat):	Aip (AHR interacting HSP90 co-chaperone)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Homo sapiens (human):	AIP (AHR interacting HSP90 co-chaperone)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Aip (aryl-hydrocarbon receptor-interacting protein)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	aip (aryl hydrocarbon receptor interacting protein)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	CG1847	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	CG1847	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)
Caenorhabditis elegans (roundworm):	aipr-1	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	aip	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB)
Xenopus tropicalis (tropical clawed frog):	aip	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	1	210,837,473 - 210,848,691 (-)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	1	210,836,755 - 210,848,634 (-)	Ensembl				GRCr8
mRatBN7.2	1	201,408,002 - 201,419,220 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	1	201,407,288 - 201,419,122 (-)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	1	209,760,253 - 209,771,414 (-)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	1	216,853,484 - 216,864,639 (-)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	1	209,544,497 - 209,555,652 (-)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	1	219,361,859 - 219,373,924 (-)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	1	219,361,860 - 219,374,014 (-)	Ensembl			rn6	Rnor6.0
Rnor_5.0	1	226,232,510 - 226,244,576 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	1	206,697,248 - 206,704,457 (-)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	1	198,951,810 - 198,959,237 (-)	NCBI		Celera
RGSC_v3.1	1	206,850,700 - 206,857,910 (-)	NCBI
Cytogenetic Map	1	q43	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

ACTH-secreting pituitary adenoma (ISO)

adenoma (ISO)

Familial Isolated Pituitary Adenoma (ISO)

growth hormone secreting pituitary adenoma (ISO)

Hereditary Neoplastic Syndromes (ISO)

pituitary adenoma 1 (ISO)

pituitary adenoma 5 (ISO)

pituitary-dependent Cushing's disease (ISO)

Symmetric Acroleukopathy (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1,2-dimethylhydrazine (ISO)

17beta-estradiol (ISO)

17beta-hydroxy-17-methylestra-4,9,11-trien-3-one (ISO)

2,3',4,4',5-Pentachlorobiphenyl (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2,4,6-trinitrotoluene (EXP)

2-hydroxypropanoic acid (ISO)

3-chloropropane-1,2-diol (EXP)

3-isobutyl-1-methyl-7H-xanthine (ISO)

9-cis-retinoic acid (ISO)

all-trans-4-oxoretinoic acid (ISO)

all-trans-retinoic acid (ISO)

ammonium chloride (EXP)

apigenin (ISO)

arsenite(3-) (EXP)

benzene (EXP)

benzo[a]pyrene (ISO)

Benzo[ghi]perylene (ISO)

bis(2-ethylhexyl) phthalate (EXP)

bisphenol A (EXP)

bisphenol F (ISO)

bromobenzene (EXP)

cadmium dichloride (EXP)

caffeine (ISO)

clofibrate (ISO)

cyclosporin A (ISO)

dexamethasone (ISO)

dextran sulfate (ISO)

Dibutyl phosphate (ISO)

dibutyl phthalate (ISO)

disodium selenite (ISO)

doxorubicin (ISO)

elemental selenium (ISO)

endosulfan (EXP)

enzyme inhibitor (ISO)

Evodiamine (ISO)

indometacin (ISO)

isotretinoin (ISO)

ivermectin (ISO)

kaempferol (ISO)

methotrexate (ISO)

N-ethyl-N-nitrosourea (ISO)

nefazodone (EXP)

nitric oxide (ISO)

rac-lactic acid (ISO)

rotenone (ISO)

selenium atom (ISO)

sodium arsenite (ISO)

sunitinib (ISO)

temozolomide (ISO)

tert-butyl hydroperoxide (ISO)

thapsigargin (EXP)

titanium dioxide (ISO)

trichostatin A (ISO)

triphenyl phosphate (ISO)

valproic acid (ISO)

vinclozolin (EXP)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

protein maturation (IEA,ISO,ISS)

protein targeting to mitochondrion (IEA,ISO,ISS)

xenobiotic metabolic process (ISO)

Cellular Component

aryl hydrocarbon receptor complex (IEA,ISO)

cytoplasm (IEA)

cytosol (IEA,ISO)

membrane (IEA,ISO)

plasma membrane (IEA,ISO)

Molecular Function

aryl hydrocarbon receptor binding (IEA,ISO)

enzyme binding (IPI)

GAF domain binding (IEA,ISO)

peptidyl-prolyl cis-trans isomerase activity (IEA,ISO)

protein binding (IPI,ISO)

transcription coregulator activity (IEA,ISO)

unfolded protein binding (IEA,ISO,ISS)

References

References - curated

#	Reference Title	Reference Citation
1.	Attenuation of the Activity of the cAMP-specific Phosphodiesterase PDE4A5 by Interaction with the Immunophilin XAP2.	Bolger GB, etal., J Biol Chem 2003 Aug 29;278(35):33351-63.
2.	Phosphodiesterase 2A forms a complex with the co-chaperone XAP2 and regulates nuclear translocation of the aryl hydrocarbon receptor.	de Oliveira SK, etal., J Biol Chem. 2007 May 4;282(18):13656-63. Epub 2007 Feb 28.
3.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
4.	Rat ISS GO annotations from MGI mouse gene data--August 2006	MGD data from the GO Consortium
5.	OMIM Disease Annotation Pipeline	OMIM Disease Annotation Pipeline
6.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
7.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:9083006	PMID:12477932	PMID:14557246	PMID:15082773	PMID:16085934	PMID:18078967	PMID:19366855	PMID:21323643	PMID:23702468	PMID:27706259	PMID:34588620

Genomics

Comparative Map Data

Aip
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	1	210,837,473 - 210,848,691 (-)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	1	210,836,755 - 210,848,634 (-)	Ensembl				GRCr8
mRatBN7.2	1	201,408,002 - 201,419,220 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	1	201,407,288 - 201,419,122 (-)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	1	209,760,253 - 209,771,414 (-)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	1	216,853,484 - 216,864,639 (-)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	1	209,544,497 - 209,555,652 (-)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	1	219,361,859 - 219,373,924 (-)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	1	219,361,860 - 219,374,014 (-)	Ensembl			rn6	Rnor6.0
Rnor_5.0	1	226,232,510 - 226,244,576 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	1	206,697,248 - 206,704,457 (-)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	1	198,951,810 - 198,959,237 (-)	NCBI		Celera
RGSC_v3.1	1	206,850,700 - 206,857,910 (-)	NCBI
Cytogenetic Map	1	q43	NCBI

AIP
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	11	67,483,026 - 67,491,103 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	11	67,468,174 - 67,491,154 (+)	Ensembl			hg38	GRCh38
GRCh37	11	67,250,497 - 67,258,574 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	11	67,007,097 - 67,015,150 (+)	NCBI	Build 36	Build 36	hg18	NCBI36
Build 34	11	67,007,096 - 67,015,150	NCBI
Celera	11	64,584,240 - 64,592,315 (+)	NCBI		Celera
Cytogenetic Map	11	q13.2	NCBI
HuRef	11	63,579,484 - 63,587,558 (+)	NCBI		HuRef
CHM1_1	11	67,133,548 - 67,141,623 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	11	67,462,305 - 67,485,230 (+)	NCBI		T2T-CHM13v2.0

Aip
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	19	4,163,756 - 4,177,233 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	19	4,164,446 - 4,175,858 (-)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	19	4,113,756 - 4,126,559 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	19	4,114,446 - 4,125,858 (-)	Ensembl			mm10	GRCm38
MGSCv37	19	4,114,446 - 4,125,827 (-)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	19	4,114,446 - 4,125,827 (-)	NCBI		MGSCv36	mm8
Celera	19	3,985,348 - 3,992,447 (-)	NCBI		Celera
Cytogenetic Map	19	A	NCBI
cM Map	19	3.82	NCBI

Aip
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955422	17,997,683 - 18,004,201 (-)	Ensembl
ChiLan1.0	NW_004955422	17,997,683 - 18,003,888 (-)	NCBI	ChiLan1.0	ChiLan1.0

AIP
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	9	68,708,273 - 68,718,181 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	11	69,752,649 - 69,760,766 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	11	62,841,377 - 62,849,664 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	11	66,152,669 - 66,160,898 (+)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	11	66,152,670 - 66,160,898 (+)	Ensembl			panPan2	panpan1.1

AIP
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	18	49,986,582 - 49,992,756 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	18	49,986,587 - 49,992,676 (-)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	18	48,597,113 - 48,603,280 (-)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	18	50,909,012 - 50,914,972 (-)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	18	50,909,022 - 50,914,904 (-)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	18	50,122,349 - 50,128,309 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	18	49,696,867 - 49,702,827 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	18	50,491,120 - 50,497,293 (-)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Aip
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404947	5,832,074 - 5,837,873 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936599	2,274,448 - 2,280,504 (-)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936599	2,274,451 - 2,280,486 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

AIP
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	2	5,041,990 - 5,048,781 (-)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	2	5,042,883 - 5,048,885 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	2	3,761,439 - 3,767,460 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

AIP
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	1	6,774,648 - 6,783,095 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	1	6,773,364 - 6,783,318 (-)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM
Vero_WHO_p1.0	NW_023666038	104,058,162 - 104,066,714 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Aip
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624767	19,045,389 - 19,051,747 (-)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
HetGla 1.0	NW_004624767	19,045,559 - 19,051,876 (-)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Aip
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	2	3,516,520 - 3,527,578 (+)	NCBI		Rrattus_CSIRO_v1

Variants

Variants in Aip
84 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	129
Count of miRNA genes:	100
Interacting mature miRNAs:	115
Transcripts:	ENSRNOT00000000599
Prediction methods:	Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1578778	Pur4	Proteinuria QTL 4	3.3	0.003	urine total protein amount (VT:0000032)	urine total protein excretion rate (CMO:0000756)	1	160111531	262090437	Rat
1354646	Kidm18	Kidney mass QTL 18	5.7		kidney mass (VT:0002707)	calculated kidney weight (CMO:0000160)	1	160573753	266453731	Rat
1357335	Bw39	Body weight QTL 39	3.3		body mass (VT:0001259)	body weight (CMO:0000012)	1	207243873	252243873	Rat
1354652	Kidm20	Kidney mass QTL 20	4.3		kidney mass (VT:0002707)	calculated kidney weight (CMO:0000160)	1	186658830	266453731	Rat
1354653	Despr9	Despair related QTL 9		0.00019	locomotor behavior trait (VT:0001392)	amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)	1	177339686	222339686	Rat
2293673	Bss27	Bone structure and strength QTL 27	18.63	0.0001	femur morphology trait (VT:0000559)	femur midshaft cortical cross-sectional area (CMO:0001663)	1	181059071	226059071	Rat
2293677	Bss41	Bone structure and strength QTL 41	9.38	0.0001	lumbar vertebra size trait (VT:0010518)	lumbar vertebra cross-sectional area (CMO:0001689)	1	181059071	226059071	Rat
1549830	Bss1	Bone structure and strength QTL 1	4.8		femur strength trait (VT:0010010)	femur ultimate force (CMO:0001675)	1	182039247	227039247	Rat
70163	Bw20	Body weight QTL 20	5.1		body mass (VT:0001259)	body weight (CMO:0000012)	1	183564652	228564652	Rat
1600395	Niddm69	Non-insulin dependent diabetes mellitus QTL 69	4.14	0.0002	blood insulin amount (VT:0001560)	plasma insulin level (CMO:0000342)	1	205233991	267096252	Rat
1354624	Cm35	Cardiac mass QTL35	5.7		heart left ventricle mass (VT:0007031)	calculated heart weight (CMO:0000073)	1	186658830	266453731	Rat
1600396	Niddm68	Non-insulin dependent diabetes mellitus QTL 68	4.97	0.0003	blood glucose amount (VT:0000188)	blood glucose level area under curve (AUC) (CMO:0000350)	1	205233991	267096252	Rat
1600397	Edcs4	Endometrial carcinoma susceptibility QTL 4	2.2		uterus morphology trait (VT:0001120)	percentage of study population developing endometrioid carcinoma during a period of time (CMO:0001759)	1	176288899	270518180	Rat
631838	Niddm36	Non-insulin dependent diabetes mellitus QTL 36		0.01	insulin secretion trait (VT:0003564)	calculated pancreatic islet insulin release measurement (CMO:0001217)	1	193964073	238964073	Rat
1549837	Hcar15	Hepatocarcinoma resistance QTL 15		0.05	liver integrity trait (VT:0010547)	liver tumorous lesion number (CMO:0001068)	1	162548015	270518180	Rat
2293689	Bss47	Bone structure and strength QTL 47	7.25	0.0001	lumbar vertebra size trait (VT:0010518)	lumbar vertebra trabecular cross-sectional area (CMO:0001692)	1	181059071	226059071	Rat
152025235	Bw194	Body weight QTL 194	4.86		body mass (VT:0001259)		1	132966869	252856240	Rat
1600388	Niddm67	Non-insulin dependent diabetes mellitus QTL 67	5.84	0.000004	blood glucose amount (VT:0000188)	blood glucose level area under curve (AUC) (CMO:0000350)	1	205233991	267096252	Rat
61341	Bp26	Blood pressure QTL 26			arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	139442053	223964440	Rat
1598853	Memor3	Memory QTL 3	4.5		exploratory behavior trait (VT:0010471)	total horizontal distance resulting from voluntary locomotion in an experimental apparatus (CMO:0001443)	1	152919152	268496042	Rat
1578759	Uae30	Urinary albumin excretion QTL 30	3.3	0.003	urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	1	160111531	262090437	Rat
2293693	Bss22	Bone structure and strength QTL 22	33.52	0.0001	femur morphology trait (VT:0000559)	femur cross-sectional area (CMO:0001661)	1	181059071	226059071	Rat
1358902	Bw47	Body weight QTL 47	1.67		body mass (VT:0001259)	body weight (CMO:0000012)	1	99645382	221502378	Rat
2300161	Bmd43	Bone mineral density QTL 43	8.4	0.0001	femur mineral mass (VT:0010011)	volumetric bone mineral density (CMO:0001553)	1	181059071	226059071	Rat
1300145	Rf7	Renal function QTL 7	2.96		urine creatinine amount (VT:0010540)	urine creatinine level (CMO:0000125)	1	194575422	239575422	Rat
61347	Bp197	Blood pressure QTL 197	4.2		arterial blood pressure trait (VT:2000000)	blood pressure measurement (CMO:0000003)	1	168063662	213063662	Rat
8655655	Arrd2	Age-related retinal degeneration QTL 2	7.79		retinal layer morphology trait (VT:0003727)	percentage of study population developing retinopathy during a period of time (CMO:0002453)	1	193400541	238400541	Rat
1358898	Bp255	Blood pressure QTL 255	3.6		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	1	200449456	256003563	Rat
631214	Bw61	Body weight QTL61	3.4	0.0001	intramuscular adipose amount (VT:0010044)	intramuscular fat area (CMO:0001162)	1	182535316	227535316	Rat
7771612	Cm80	Cardiac mass QTL 80	8.4		heart left ventricle mass (VT:0007031)	heart left ventricle weight (CMO:0000776)	1	146080545	243492863	Rat
731168	Bp154	Blood pressure QTL 154	3.4		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	103779152	223964440	Rat
731175	Uae20	Urinary albumin excretion QTL 20	3.5	0.0018	urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	1	207163993	269633915	Rat
2300174	Bmd42	Bone mineral density QTL 42	8.4	0.0001	lumbar vertebra mineral mass (VT:0010511)	bone mineral density (CMO:0001226)	1	181059071	226059071	Rat
737828	Hcas3	Hepatocarcinoma susceptibility QTL 3	4.9		liver integrity trait (VT:0010547)	liver tumorous lesion volume to total liver volume ratio (CMO:0001082)	1	153679879	232414077	Rat
1354661	Bw33	Body weight QTL 33	5.2		body mass (VT:0001259)	body weight (CMO:0000012)	1	160573753	266453731	Rat
1358886	Bp260	Blood pressure QTL 260	3.67		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	1	160574007	235238518	Rat
2293654	Bss30	Bone structure and strength QTL 30	32.65	0.0001	femur strength trait (VT:0010010)	femur midshaft polar moment of inertia (CMO:0001669)	1	181059071	226059071	Rat
1298084	Thym4	Thymus enlargement QTL 4	10.68		thymus mass (VT:0004954)	thymus weight to body weight ratio (CMO:0000612)	1	207243873	252243873	Rat
724531	Uae5	Urinary albumin excretion QTL 5	4		urine albumin amount (VT:0002871)	urine albumin level (CMO:0000130)	1	160111426	262090599	Rat
2300187	Bmd41	Bone mineral density QTL 41	8.9	0.0001	femur mineral mass (VT:0010011)	volumetric bone mineral density (CMO:0001553)	1	181059071	226059071	Rat
2314011	Gluco56	Glucose level QTL 56			blood glucose amount (VT:0000188)	blood glucose level area under curve (AUC) (CMO:0000350)	1	209203273	254203273	Rat
8552891	Epfw5	Epididymal fat weight QTL 5	4.4		epididymal fat pad mass (VT:0010421)	epididymal fat pad weight to body weight ratio (CMO:0000658)	1	202543537	247543537	Rat
1354580	Scort1	Serum corticosterone level QTL 1	3.4		blood corticosterone amount (VT:0005345)	blood corticosterone level (CMO:0001172)	1	154961463	266453731	Rat
1358292	Cm37	Cardiac mass QTL 37	6.2	8e-07	heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	1	205674651	250674651	Rat
61376	Bp42	Blood pressure QTL 42	23.4		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	207243873	252243873	Rat
634313	Niddm43	Non-insulin dependent diabetes mellitus QTL 43			blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	1	208479811	269633915	Rat
634312	Bp143	Blood pressure QTL 143	3	0.0002	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	203300512	229359342	Rat
1358294	Bw37	Body weight QTL 37	5	0.000011	body mass (VT:0001259)	body weight (CMO:0000012)	1	180739993	225739993	Rat
724559	Pancm1	Pancreatic morphology QTL 1	7.1		islet of Langerhans morphology trait (VT:0005215)	pancreatic islet damage composite score (CMO:0001156)	1	191190115	223964326	Rat
2312420	Pur17	Proteinuria QTL 17	7.1	0.0001	urine protein amount (VT:0005160)	urine total protein excretion rate (CMO:0000756)	1	172718770	228180370	Rat
10059600	Bp378	Blood pressure QTL 378	3.08	0.05	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	186298393	231298393	Rat
2312564	Glom18	Glomerulus QTL 18	2.4	0.003	kidney glomerulus morphology trait (VT:0005325)	index of glomerular damage (CMO:0001135)	1	194786607	262083703	Rat
634321	Hc1	Hypercalciuria QTL 1	2.91		urine calcium amount (VT:0002985)	urine calcium excretion rate (CMO:0000763)	1	188241285	250779312	Rat
2292218	Kidm35	Kidney mass QTL 35			kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	1	208798288	253798288	Rat
724562	Rends1	Renal damage susceptibility QTL 1		0.05	kidney glomerulus integrity trait (VT:0010546)	index of glomerular damage (CMO:0001135)	1	139442053	223964440	Rat
1300168	Bp170	Blood pressure QTL 170	2.76		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	1	192995199	237995199	Rat
61403	Niddm4	Non-insulin dependent diabetes mellitus QTL 4			blood glucose amount (VT:0000188)	plasma glucose level (CMO:0000042)	1	201464383	246464383	Rat
2292222	Bp307	Blood pressure QTL 307	3.06	0.0014	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	186298393	231298393	Rat
2292220	Bp306	Blood pressure QTL 306	3.47	0.00087	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	186298393	231298393	Rat
1641926	Teswt2	Testicular weight QTL 2	2.82		testis mass (VT:1000644)	both testes wet weight (CMO:0000175)	1	203675682	248675682	Rat
631658	Cm7	Cardiac mass QTL 7	5.32	0.0001	aorta mass (VT:0002845)	aorta weight (CMO:0000076)	1	205674651	250674651	Rat
1600380	Niddm70	Non-insulin dependent diabetes mellitus QTL 70	3.1	0.0008	blood insulin amount (VT:0001560)	plasma insulin level (CMO:0000342)	1	185979875	230979875	Rat
1354610	Bw34	Body weight QTL 34	4.1		body mass (VT:0001259)	body weight (CMO:0000012)	1	160573753	266453731	Rat
1582206	Kidm33	Kidney mass QTL 33	6.9		kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	1	197807365	233480676	Rat
8655855	Arrd3	Age-related retinal degeneration QTL 3	3.07		lens clarity trait (VT:0001304)	cataract incidence/prevalence measurement (CMO:0001585)	1	193400541	238400541	Rat
634338	Hcar4	Hepatocarcinoma resistance QTL 4	4.6		liver integrity trait (VT:0010547)	liver tumorous lesion number to liver area ratio (CMO:0001210)	1	202851915	223964440	Rat
6480783	Insul19	Insulin level QTL 19	4.33		blood insulin amount (VT:0001560)	plasma insulin level (CMO:0000342)	1	203300512	213659238	Rat
6903303	Scl34	Serum cholesterol QTL 34	2.5	0.0033	blood cholesterol amount (VT:0000180)	plasma total cholesterol level (CMO:0000585)	1	173363824	227535316	Rat
1600374	Mcs17	Mammary carcinoma susceptibility QTL 17	3		mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	1	207099883	252099883	Rat
2293083	Iddm25	Insulin dependent diabetes mellitus QTL 25	4.18		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	1	191260175	236260175	Rat
1354606	Bp246	Blood pressure QTL 246	3.6		arterial blood pressure trait (VT:2000000)	pulse pressure (CMO:0000292)	1	111949780	228180370	Rat
738032	Hcas5	Hepatocarcinoma susceptibility QTL 5	3.12		liver integrity trait (VT:0010547)	liver tumorous lesion number (CMO:0001068)	1	185857683	270518180	Rat
2325727	Pia41	Pristane induced arthritis QTL 41			joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	1	188241285	233241285	Rat

Markers in Region

RH124747

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	1	201,408,194 - 201,408,315 (+)	MAPPER	mRatBN7.2
Rnor_6.0	1	219,362,767 - 219,362,887	NCBI	Rnor6.0
Rnor_5.0	1	226,233,418 - 226,233,538	UniSTS	Rnor5.0
RGSC_v3.4	1	206,698,156 - 206,698,276	UniSTS	RGSC3.4
Celera	1	198,952,719 - 198,952,839	UniSTS
Cytogenetic Map	1	q42	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
16	12	67	165	91	90	59	92	59	6	356	192	11	144	81	92	31	17	17

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_172327	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006230700	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AF543560	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC089110	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473953	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ214270	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ228146	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000001	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000000599 ⟹ ENSRNOP00000000599

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	1	210,836,755 - 210,844,184 (-)	Ensembl
mRatBN7.2 Ensembl	1	201,407,288 - 201,411,787 (-)	Ensembl
Rnor_6.0 Ensembl	1	219,361,860 - 219,369,587 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000091542 ⟹ ENSRNOP00000075162

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	1	210,837,473 - 210,848,634 (-)	Ensembl
mRatBN7.2 Ensembl	1	201,408,010 - 201,419,122 (-)	Ensembl
Rnor_6.0 Ensembl	1	219,362,552 - 219,374,014 (-)	Ensembl

RefSeq Acc Id:

NM_172327 ⟹ NP_758830

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	1	210,837,473 - 210,848,634 (-)	NCBI
mRatBN7.2	1	201,408,006 - 201,419,172 (-)	NCBI
Rnor_6.0	1	219,361,859 - 219,369,587 (-)	NCBI
Rnor_5.0	1	226,232,510 - 226,244,576 (-)	NCBI
RGSC_v3.4	1	206,697,248 - 206,704,457 (-)	RGD
Celera	1	198,951,810 - 198,959,237 (-)	RGD

Sequence:

show sequence

GGAGGATGGCGGATCTCATCGCAAGACTTCGAGAGGACGGGATCCAAAAGCGTGTGATACAGGA
GGGCCGAGGAGAGTTGCCGGAATTTCAGGATGGCACTAAGGCCACCTTCCACTTCCGGACGCTG
CATAGTGACCCGGAGGGCTCCGTCATAGATGACAGCCGAGCACGCGGCAAGCCCATGGAGCTCA
TCATCGGCAAGAAGTTCAAGCTGCCTGTGTGGGAGACCATCGTGCGTACCATGCGTGAGGGGGA
GACGGCCCAGTTCCTCTGCGATGTCAAGCACACAGTCCTGTATCCTCTGGTGGCCAAGAGCCTC
CGCAACATCGCTGAGGGCAAGGACCCCTTGGAGGGCCAGCGGCATTGCTGTGGAATTGCTCAAA
TGCATGAGCATAGCTCCCTGGGTCATGCGGACCTGGACGCCCTGCAGCAGAACCCTCAACCCCT
CATCTTCCACATCGAGATGCTGAAGGTGGAGAGCCCTGGCACCTACCAGCAGGACCCATGGGCA
ATGACAGATGAGGAGAAAGCAAAGGCAGTACCACTCATCCACCAAGAGGGCAACCGCTTATACC
GTGAGGGGCAGGTGAAGGAGGCTGCTGCCAAGTACTACGATGCCATTGCCTGCCTCAAGAACCT
GCAGATGAAGGAGCAGCCTGGATCACCCGACTGGATCCAGTTGGACTTGCAGATCACACCACTG
CTACTCAACTATTGCCAGTGCAAGCTGGTGGCTCAGGAGTACTATGAGGTGCTGGATCACTGCT
CCTCCATCCTCAACAAGTATGATGACAATGTCAAGGCTTACTTCAAGCGGGGTAAGGCCCATGC
TGCTGTGTGGAATGCCCAGGAGGCCCAGGCTGACTTTGCCAAGGTGTTGGAGCTCGACCCTGCC
CTGGCGCCTGTGGTAAGCAGAGAGCTGCGGGCCCTGGAGGCACGGATCCGGCAGAAGGATGAGG
AGGACAAAGCCCGCTTCCGGGGCATCTTTTCCCACTAACAGGACCTCAGTTCTGCCCTGCCCTG
CCAAGCCCACTGCTGCCACCACCTGTCAATCCCCCACTGCCACCTTGTGCTTCTGTGTATATAA
AGGCCTTATTTATCTCTCTGGCTTTGCAGAGCTAATCCGTCCTGAAGGCTGGTCCTCAGTGGCC
AGGTGCTTGGTAGTCAGTGGGAGGGAAGAATTCAGGGTCTTACCTAGTTCCCTACTGGTTTGTG
GTAAAGTCTCTGGGAGTTTCTTTCTGGCAAGTACCAGCTTCCTCTAGTATTAAGTTGTAGAGAA
AGCAGGCATGGTTCACACAGGCCACAGTTCCAGCCTTAGGTCCCTCAGTCCTTGGCTTTTGGTT
TTGGAGACAGAAGTTTCCTTAGGGGCATAGGTGAGGAGAGCTGTAGAGTTAGACTCCACATGAC
TCAAGCAGTGTCTGAGGTTGAGGACAGGAGAAGGGATAGGCAGACTATCTAGGAAATGCCCTAG
GAAAGTACAGCCAGGGCCCTTGGGGAAAGTGAAAGTGAAGGGGCTCCAGTTGCCCTACTCTATG
ACCCTGAGCAGGTCCTGGCCCCTTTTAGCACCTCAGAGTCCCAGACAGGAAAGGCCTTGGTAGA
GTGCAGTTTAATTTTATAGGTTCACACATTGGAAAAGCTGCTGGACCCTAGCCCACTCCCTCCT
TCCTCCCCTCGGGGGTAGGAAGTAATCCCCCACTAAGGGAAGTAATACTGAGGAGTAGTCATAC
AGGGTGTGGGGCCAGGGCTGGGGCCAAAGGTCTAGGCCCCAGCCTCCCACAGTCACTCAGGCCC
CTTGAGTATCAATAAATAACCCAGGTCCAGCCAAAAAAAAAAAAAAAAAAAAAAAAAGG

hide sequence

RefSeq Acc Id:

XM_006230700 ⟹ XP_006230762

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	1	210,837,473 - 210,848,691 (-)	NCBI
mRatBN7.2	1	201,408,002 - 201,419,220 (-)	NCBI
Rnor_6.0	1	219,361,863 - 219,373,924 (-)	NCBI
Rnor_5.0	1	226,232,510 - 226,244,576 (-)	NCBI

Sequence:

show sequence

CCGAGTTGATTCGGGAATCACGTCAGAGTCTCGCGGGTAGCGGGACTCGCGGCGCCACCCAGAG
GCTACCTTGTCAAAATGGCGCTTGCTCAGAAGCTGCCCAGGCTCTAGGAGTTGCCGAAACAGGT
CCGGAAGCTACCGAGCGAGTCCGGAAGTTGCCGAAAGGGAGCAGCGGGGAAGGAGGATGGCGGA
TCTCATCGCAAGACTTCGAGAGGACGGGATCCAAAAGCGTGTGATACAGGAGGGCCGAGGAGAG
TTGCCGGAATTTCAGGATGGCACTAAGGCCACCTTCCACTTCCGGACGCTGCATAGTGACCCGG
AGGGCTCCGTCATAGATGACAGCCGAGCACGCGGCAAGCCCATGGAGCTCATCATCGGCAAGAA
GTTCAAGCTGCCTGTGTGGGAGACCATCGTGCGTACCATGCGTGAGGGGGAGACGGCCCAGTTC
CTCTGCGATGTCAAGCACACAGTCCTGTATCCTCTGGTGGCCAAGAGCCTCCGCAACATCGCTG
AGGGCAAGGACCCCTTGGAGGGCCAGCGGCATTGCTGTGGAATTGCTCAAATGCATGAGCATAG
CTCCCTGGGTCATGCGGACCTGGACGCCCTGCAGCAGAACCCTCAACCCCTCATCTTCCACATC
GAGATGCTGAAGGTGGAGAGCCCTGGCACCTACCAGCAGGACCCATGGGCAATGACAGATGAGG
AGAAAGCAAAGGCAGTACCACTCATCCACCAAGAGGGCAACCGCTTATACCGTGAGGGGCAGGT
GAAGGAGGCTGCTGCCAAGTACTACGATGCCATTGCCTGCCTCAAGAACCTGCAGATGAAGGAG
CAGCCTGGATCACCCGACTGGATCCAGTTGGACTTGCAGATCACACCACTGCTACTCAACTATT
GCCAGTGCAAGCTGGTGGCTCAGGAGTACTATGAGGTGCTGGATCACTGCTCCTCCATCCTCAA
CAAGTATGATGACAATGTCAAGGCTTACTTCAAGCGGGGTAAGGCCCATGCTGCTGTGTGGAAT
GCCCAGGAGGCCCAGGCTGACTTTGCCAAGGTGTTGGAGCTCGACCCTGCCCTGGCGCCTGTGG
TAAGCAGAGAGCTGCGGGCCCTGGAGGCACGGATCCGGCAGAAGGATGAGGAGGACAAAGCCCG
CTTCCGGGGCATCTTTTCCCACTAACAGGACCTCAGTTCTGCCCTGCCCTGCCAAGCCCACTGC
TGCCACCACCTGTCAATCCCCCACTGCCACCTTGTGCTTCTGTGTATATAAAGGCCTTATTTAT
CTCTCTGGCTTTGCAGAGCTAATCCGTCCTGAAGGCTGGTCCTCAGTGGCCAGGTGCTTGGTAG
TCAGTGGGAGGGAAGAATTCAGGGTCTTACCTAGTTCCCTACTGGTTTGTGGTAAAGTCTCTGG
GAGTTTCTTTCTGGCAAGTACCAGCTTCCTCTAGTATTAAGTTGTAGAGAAAGCAGGCATGGTT
CACACAGGCCACAGTTCCAGCCTTAGGTCCCTCAGTCCTTGGCTTTTGGTTTTGGAGACAGAAG
TTTCCTTAGGGGCATAGGTGAGGAGAGCTGTAGAGTTAGACTCCACATGACTCAAGCAGTGTCT
GAGGTTGAGGACAGGAGAAGGGATAGGCAGACTATCTAGGAAATGCCCTAGGAAAGTACAGCCA
GGGCCCTTGGGGAAAGTGAAAGTGAAGGGGCTCCAGTTGCCCTACTCTATGACCCTGAGCAGGT
CCTGGCCCCTTTTAGCACCTCAGAGTCCCAGACAGGAAAGGCCTTGGTAGAGTGCAGTTTAATT
TTATAGGTTCACACATTGGAAAAGCTGCTGGACCCTAGCCCACTCCCTCCTTCCTCCCCTCGGG
GGTAGGAAGTAATCCCCCACTAAGGGAAGTAATACTGAGGAGTAGTCATACAGGGTGTGGGGCC
AGGGCTGGGGCCAAAGGTCTAGGCCCCAGCCTCCCACAGTCACTCAGGCCCCTTGAGTATCAAT
AAATAACCCAGGTCCA

hide sequence

Protein Sequences


Protein RefSeqs	NP_758830	(Get FASTA)	NCBI Sequence Viewer
	XP_006230762	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAH89110	(Get FASTA)	NCBI Sequence Viewer
	AAN77242	(Get FASTA)	NCBI Sequence Viewer
	EDM12365	(Get FASTA)	NCBI Sequence Viewer
	EDM12366	(Get FASTA)	NCBI Sequence Viewer
	EDM12367	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000075162
	ENSRNOP00000075162.1
GenBank Protein	Q5FWY5	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

NP_758830 ⟸ NM_172327

- UniProtKB:

Q8CGW7 (UniProtKB/Swiss-Prot), Q5FWY5 (UniProtKB/Swiss-Prot), A6HYT6 (UniProtKB/TrEMBL), A0A8L2PZ29 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MADLIARLREDGIQKRVIQEGRGELPEFQDGTKATFHFRTLHSDPEGSVIDDSRARGKPMELII
GKKFKLPVWETIVRTMREGETAQFLCDVKHTVLYPLVAKSLRNIAEGKDPLEGQRHCCGIAQMH
EHSSLGHADLDALQQNPQPLIFHIEMLKVESPGTYQQDPWAMTDEEKAKAVPLIHQEGNRLYRE
GQVKEAAAKYYDAIACLKNLQMKEQPGSPDWIQLDLQITPLLLNYCQCKLVAQEYYEVLDHCSS
ILNKYDDNVKAYFKRGKAHAAVWNAQEAQADFAKVLELDPALAPVVSRELRALEARIRQKDEED
KARFRGIFSH

hide sequence

RefSeq Acc Id:	XP_006230762 ⟸ XM_006230700
- Peptide Label:	isoform X1
- UniProtKB:	Q8CGW7 (UniProtKB/Swiss-Prot), Q5FWY5 (UniProtKB/Swiss-Prot), A6HYT6 (UniProtKB/TrEMBL), A0A8L2PZ29 (UniProtKB/TrEMBL)
- Sequence:	show sequence MADLIARLREDGIQKRVIQEGRGELPEFQDGTKATFHFRTLHSDPEGSVIDDSRARGKPMELII GKKFKLPVWETIVRTMREGETAQFLCDVKHTVLYPLVAKSLRNIAEGKDPLEGQRHCCGIAQMH EHSSLGHADLDALQQNPQPLIFHIEMLKVESPGTYQQDPWAMTDEEKAKAVPLIHQEGNRLYRE GQVKEAAAKYYDAIACLKNLQMKEQPGSPDWIQLDLQITPLLLNYCQCKLVAQEYYEVLDHCSS ILNKYDDNVKAYFKRGKAHAAVWNAQEAQADFAKVLELDPALAPVVSRELRALEARIRQKDEED KARFRGIFSH hide sequence

Ensembl Acc Id:

ENSRNOP00000000599 ⟸ ENSRNOT00000000599

Ensembl Acc Id:

ENSRNOP00000075162 ⟸ ENSRNOT00000091542

Protein Domains

AIP/AIPL N-terminal FKBP-type PPIase PPIase FKBP-type

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q5FWY5-F1-model_v2	AlphaFold	Q5FWY5	1-330	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13690612

Promoter ID:

EPDNEW_R1137

Type:

multiple initiation site

Name:

Aip_1

Description:

aryl-hydrocarbon receptor-interacting protein

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	1	219,369,616 - 219,369,676	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:628619	AgrOrtholog
BioCyc Gene	G2FUF-56777	BioCyc
Ensembl Genes	ENSRNOG00000022289	Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript	ENSRNOT00000091542	ENTREZGENE
	ENSRNOT00000091542.2	UniProtKB/Swiss-Prot
Gene3D-CATH	1.25.40.10	UniProtKB/Swiss-Prot
	3.10.50.40	UniProtKB/Swiss-Prot
IMAGE_CLONE	IMAGE:7311852	IMAGE-MGC_LOAD
InterPro	AIP/AIPL1	UniProtKB/Swiss-Prot
	PPIase_AIP	UniProtKB/Swiss-Prot
	PPIase_dom_sf	UniProtKB/Swiss-Prot
	PPIase_FKBP_dom	UniProtKB/Swiss-Prot
	TPR-like_helical_dom_sf	UniProtKB/Swiss-Prot
	TPR_repeat	UniProtKB/Swiss-Prot
KEGG Report	rno:282827	UniProtKB/Swiss-Prot
MGC_CLONE	MGC:105297	IMAGE-MGC_LOAD
NCBI Gene	282827	ENTREZGENE
PANTHER	PTHR11242	UniProtKB/Swiss-Prot
	PTHR11242:SF3	UniProtKB/Swiss-Prot
Pfam	PPIase_AIP	UniProtKB/Swiss-Prot
PhenoGen	Aip	PhenoGen
PROSITE	FKBP_PPIASE	UniProtKB/Swiss-Prot
	TPR	UniProtKB/Swiss-Prot
	TPR_REGION	UniProtKB/Swiss-Prot
RatGTEx	ENSRNOG00000022289	RatGTEx
Superfamily-SCOP	FKBP-like	UniProtKB/Swiss-Prot
	SSF48452	UniProtKB/Swiss-Prot
UniProt	A0A8L2PZ29	ENTREZGENE, UniProtKB/TrEMBL
	A6HYT4_RAT	UniProtKB/TrEMBL
	A6HYT5_RAT	UniProtKB/TrEMBL
	A6HYT6	ENTREZGENE, UniProtKB/TrEMBL
	AIP_RAT	UniProtKB/Swiss-Prot, ENTREZGENE
	Q8CGW7	ENTREZGENE
UniProt Secondary	Q8CGW7	UniProtKB/Swiss-Prot

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2025-11-13	Aip	AHR interacting HSP90 co-chaperone	Aip	aryl-hydrocarbon receptor-interacting protein	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2005-01-20	Aip	aryl-hydrocarbon receptor-interacting protein			Symbol and Name status set to approved	1299863	APPROVED
2003-02-27	Aip	aryl-hydrocarbon receptor-interacting protein			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - OMIM

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Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - OMIM