Exoc3 (exocyst complex component 3) - Rat Genome Database

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Pathways
Gene: Exoc3 (exocyst complex component 3) Rattus norvegicus
Analyze
Symbol: Exoc3
Name: exocyst complex component 3
RGD ID: 621790
Description: Predicted to enable SNARE binding activity. Predicted to be involved in exocyst localization and exocytosis. Is active in presynaptic membrane. Orthologous to human EXOC3 (exocyst complex component 3); PARTICIPATES IN E-cadherin signaling pathway; insulin signaling pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; 3,3',4,4',5-pentachlorobiphenyl.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: exocyst complex component Sec6; rSec6; Sec6; SEC6-like 1; SEC6-like 1 (S. cerevisiae); Sec6l1
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8130,919,871 - 30,950,624 (+)NCBIGRCr8GRCr8GRCr8
mRatBN7.2129,091,298 - 29,122,056 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl129,091,294 - 29,122,045 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx128,893,113 - 28,923,914 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0134,892,975 - 34,923,773 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0129,093,734 - 29,124,536 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0131,700,953 - 31,731,726 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl131,700,953 - 31,731,815 (+)Ensemblrn6Rnor6.0
Rnor_5.0133,126,575 - 33,159,109 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4129,897,536 - 29,928,281 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera127,743,063 - 27,773,955 (+)NCBICelera
RGSC_v3.1129,902,027 - 29,931,141 (+)NCBI
Cytogenetic Map1p11NCBI
JBrowse:




Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,2-dichloroethane  (ISO)
1,2-dimethylhydrazine  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4,6-tribromophenol  (ISO)
2,4-dinitrotoluene  (EXP)
3,3',4,4',5-pentachlorobiphenyl  (EXP)
3,3',5,5'-tetrabromobisphenol A  (ISO)
3-chloropropane-1,2-diol  (EXP)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
3H-1,2-dithiole-3-thione  (EXP)
4,4'-diaminodiphenylmethane  (ISO)
4,4'-sulfonyldiphenol  (ISO)
acrolein  (ISO)
acrylamide  (ISO)
aflatoxin B1  (ISO)
all-trans-retinoic acid  (ISO)
allethrin  (EXP)
alpha-pinene  (ISO)
ammonium chloride  (EXP)
Aroclor 1254  (EXP)
arsane  (ISO)
arsenic atom  (ISO)
benzo[a]pyrene  (ISO)
beta-lapachone  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
butan-1-ol  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
caffeine  (ISO)
carbon nanotube  (ISO)
chlorpyrifos  (ISO)
cisplatin  (ISO)
copper atom  (ISO)
copper(0)  (ISO)
cyhalothrin  (EXP)
cypermethrin  (EXP)
dexamethasone  (ISO)
dibutyl phthalate  (ISO)
diuron  (EXP)
elemental selenium  (ISO)
ethanol  (ISO)
fenvalerate  (EXP)
finasteride  (EXP)
flutamide  (EXP)
formaldehyde  (ISO)
fulvestrant  (ISO)
gentamycin  (EXP,ISO)
indometacin  (ISO)
ivermectin  (ISO)
leflunomide  (EXP)
methyl methanesulfonate  (ISO)
Nor-9-carboxy-delta9-THC  (ISO)
ozone  (ISO)
phenylmercury acetate  (ISO)
piroxicam  (ISO)
potassium dichromate  (ISO)
pyrethrins  (EXP)
selenium atom  (ISO)
sodium arsenite  (ISO)
sulindac  (EXP)
tamibarotene  (ISO)
titanium dioxide  (ISO)
triphenyl phosphate  (ISO)
tungsten  (ISO)
vinclozolin  (EXP)
vitamin E  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. The glycine transporter GLYT1 interacts with Sec3, a component of the exocyst complex. Cubelos B, etal., Neuropharmacology. 2005 Nov;49(6):935-44. doi: 10.1016/j.neuropharm.2005.07.021. Epub 2005 Sep 21.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. MyRIP anchors protein kinase A to the exocyst complex. Goehring AS, etal., J Biol Chem. 2007 Nov 9;282(45):33155-67. Epub 2007 Sep 7.
4. GRIP1 and 2 regulate activity-dependent AMPA receptor recycling via exocyst complex interactions. Mao L, etal., Proc Natl Acad Sci U S A. 2010 Nov 2;107(44):19038-43. doi: 10.1073/pnas.1013494107. Epub 2010 Oct 18.
5. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
6. PID Annotation Import Pipeline Pipeline to import Pathway Interaction Database annotations from NCI into RGD
7. GOA pipeline RGD automated data pipeline
8. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
9. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
10. rSec6 and rSec8, mammalian homologs of yeast proteins essential for secretion. Ting AE, etal., Proc Natl Acad Sci U S A 1995 Oct 10;92(21):9613-7.
11. Sec6 is localized to the plasma membrane of mature synaptic terminals and is transported with secretogranin II-containing vesicles. Vik-Mo EO, etal., Neuroscience. 2003;119(1):73-85.
Additional References at PubMed
PMID:11406615   PMID:12477932   PMID:15489334   PMID:25468996  


Genomics

Comparative Map Data
Exoc3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8130,919,871 - 30,950,624 (+)NCBIGRCr8GRCr8GRCr8
mRatBN7.2129,091,298 - 29,122,056 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl129,091,294 - 29,122,045 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx128,893,113 - 28,923,914 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0134,892,975 - 34,923,773 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0129,093,734 - 29,124,536 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0131,700,953 - 31,731,726 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl131,700,953 - 31,731,815 (+)Ensemblrn6Rnor6.0
Rnor_5.0133,126,575 - 33,159,109 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4129,897,536 - 29,928,281 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera127,743,063 - 27,773,955 (+)NCBICelera
RGSC_v3.1129,902,027 - 29,931,141 (+)NCBI
Cytogenetic Map1p11NCBI
EXOC3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh385443,176 - 467,290 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl5442,522 - 471,937 (+)Ensemblhg38GRCh38
GRCh375443,291 - 467,405 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 365496,334 - 520,411 (+)NCBIBuild 36Build 36hg18NCBI36
Build 345496,374 - 520,407NCBI
Celera5541,456 - 565,545 (+)NCBICelera
Cytogenetic Map5p15.33NCBI
HuRef5431,407 - 455,422 (+)NCBIHuRef
CHM1_15443,164 - 467,222 (+)NCBICHM1_1
T2T-CHM13v2.05438,418 - 462,555 (+)NCBIT2T-CHM13v2.0
Exoc3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391374,317,921 - 74,358,151 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1374,317,607 - 74,356,851 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm381374,169,802 - 74,210,032 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1374,169,488 - 74,208,732 (-)Ensemblmm10GRCm38
MGSCv371374,307,253 - 74,346,148 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361374,635,807 - 74,674,702 (-)NCBIMGSCv36mm8
Celera1376,499,394 - 76,538,276 (-)NCBICelera
Cytogenetic Map13C1NCBI
cM Map1340.15NCBI
Exoc3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955504196,695 - 223,812 (+)Ensembl
ChiLan1.0NW_004955504195,743 - 223,812 (+)NCBIChiLan1.0ChiLan1.0
EXOC3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v24662,394 - 690,011 (+)NCBINHGRI_mPanPan1-v2
PanPan1.1 Ensembl5568,471 - 596,723 (+)EnsemblpanPan2panpan1.1
EXOC3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13411,790,927 - 11,811,566 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3411,791,926 - 11,811,561 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha3416,304,626 - 16,325,902 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.03411,695,749 - 11,716,848 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3411,694,759 - 11,716,578 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13411,746,203 - 11,767,708 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03411,727,053 - 11,748,335 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03411,937,421 - 11,958,497 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Exoc3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024407213244,844,352 - 244,861,748 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049368151,005,560 - 1,023,070 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049368151,005,637 - 1,022,916 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
EXOC3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1679,705,750 - 79,730,047 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.11679,705,743 - 79,730,272 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
EXOC3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.14320,067 - 359,647 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl4337,658 - 360,149 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366606427,462,671 - 27,487,604 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Exoc3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624751215,821 - 255,104 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_004624751215,762 - 254,200 (+)NCBIHetGla 1.0HetGla 1.0hetGla2

Variants

.
Variants in Exoc3
224 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:116
Count of miRNA genes:86
Interacting mature miRNAs:92
Transcripts:ENSRNOT00000020251
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
631688Hcas2Hepatocarcinoma susceptibility QTL 230.0001liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)1774611852746118Rat
1357397Bw41Body weight QTL 414.190.0001body mass (VT:0001259)body weight (CMO:0000012)12940927974409279Rat
2313090Bmd69Bone mineral density QTL 694.40.0001tibia mineral mass (VT:1000283)compact volumetric bone mineral density (CMO:0001730)1529322934184556Rat
4889451Eae29Experimental allergic encephalomyelitis QTL 295.51nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis severity score (CMO:0001419)1774612152746121Rat
70179Xhs2X-ray hypersensitivity QTL 23.2intestine integrity trait (VT:0010554)post-insult time to onset of moribundity (CMO:0001896)1143965634Rat
1558642Prcr2Prostate cancer resistance QTL 24.3prostate integrity trait (VT:0010571)area of ventral prostate occupied by tumorous lesions to total ventral prostate area ratio (CMO:0000899)11037949255379492Rat
7421626Bp360Blood pressure QTL 3600.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1694102251941022Rat
1357401Bw43Body weight QTL 433.75body mass (VT:0001259)body weight (CMO:0000012)1690935351909353Rat
2313070Bss52Bone structure and strength QTL 524.40.0001body length (VT:0001256)body length (CMO:0000013)1529322934184556Rat
631494Bp95Blood pressure QTL 95400.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)11731537851816258Rat
5684998Bss101Bone structure and strength QTL 1013.6tibia strength trait (VT:1000284)tibia ultimate force (CMO:0001734)1690935351909353Rat
5684999Bss102Bone structure and strength QTL 1025.57e-07tibia strength trait (VT:1000284)tibia stiffness (CMO:0001735)1690935351909353Rat
2302038Pia31Pristane induced arthritis QTL 315.50.001blood autoantibody amount (VT:0003725)serum immunoglobulin M-type rheumatoid factor level relative to an arbitrary reference serum (CMO:0002111)11282049457820494Rat
634353Rends2Renal damage susceptibility QTL 20.05kidney blood vessel morphology trait (VT:0000530)organ lesion measurement (CMO:0000677)12065642065656420Rat
2317755Glom22Glomerulus QTL 223.8urine protein amount (VT:0005160)urine protein level (CMO:0000591)1134184556Rat
1578756Iddm22Insulin dependent diabetes mellitus QTL 222.7blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)12050832665508326Rat
1331785Rf27Renal function QTL 274.643urine sodium amount (VT:0006274)urine sodium level (CMO:0000129)13070837587558729Rat
631508Sald1Serum aldosterone level QTL 13.7blood aldosterone amount (VT:0005346)serum aldosterone level (CMO:0000487)11168446456684464Rat
2313053Bss51Bone structure and strength QTL 513.80.0001tibia length (VT:0004357)tibia length (CMO:0000450)1529322934184556Rat

Markers in Region
D1Got38  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2129,098,144 - 29,098,329 (+)MAPPERmRatBN7.2
Rnor_6.0131,707,798 - 31,707,982NCBIRnor6.0
Rnor_5.0133,133,228 - 33,133,412UniSTSRnor5.0
RGSC_v3.4129,904,378 - 29,904,563RGDRGSC3.4
RGSC_v3.4129,904,379 - 29,904,563UniSTSRGSC3.4
Celera127,749,908 - 27,750,092UniSTS
RGSC_v3.1129,907,323 - 29,907,508RGD
Cytogenetic Map1p11UniSTS
RH131026  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2129,121,898 - 29,122,081 (+)MAPPERmRatBN7.2
Rnor_6.0131,731,552 - 31,731,734NCBIRnor6.0
Rnor_5.0133,156,832 - 33,157,014UniSTSRnor5.0
RGSC_v3.4129,928,133 - 29,928,315UniSTSRGSC3.4
Celera127,773,807 - 27,773,989UniSTS
Cytogenetic Map1p11UniSTS
RH142744  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2129,103,267 - 29,103,539 (+)MAPPERmRatBN7.2
Rnor_6.0131,712,921 - 31,713,192NCBIRnor6.0
Rnor_5.0133,138,201 - 33,138,472UniSTSRnor5.0
RGSC_v3.4129,909,502 - 29,909,773UniSTSRGSC3.4
Celera127,755,181 - 27,755,452UniSTS
RH 3.4 Map1342.9UniSTS
Cytogenetic Map1p11UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 165 91 90 59 92 59 6 356 192 11 144 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000020251   ⟹   ENSRNOP00000020251
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl129,091,298 - 29,122,045 (+)Ensembl
Rnor_6.0 Ensembl131,700,953 - 31,731,700 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000077740   ⟹   ENSRNOP00000072705
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl129,091,294 - 29,122,045 (+)Ensembl
Rnor_6.0 Ensembl131,702,485 - 31,731,815 (+)Ensembl
RefSeq Acc Id: NM_001024964   ⟹   NP_001020135
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8130,919,875 - 30,950,622 (+)NCBI
mRatBN7.2129,091,298 - 29,122,047 (+)NCBI
Rnor_6.0131,700,953 - 31,731,700 (+)NCBI
Rnor_5.0133,126,575 - 33,159,109 (+)NCBI
RGSC_v3.4129,897,536 - 29,928,281 (+)RGD
Celera127,743,063 - 27,773,955 (+)RGD
Sequence:
RefSeq Acc Id: XM_006227767   ⟹   XP_006227829
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8130,919,871 - 30,950,624 (+)NCBI
mRatBN7.2129,091,332 - 29,122,056 (+)NCBI
Rnor_6.0131,700,987 - 31,731,726 (+)NCBI
Rnor_5.0133,126,575 - 33,159,109 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006227768   ⟹   XP_006227830
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8130,919,890 - 30,950,624 (+)NCBI
mRatBN7.2129,091,543 - 29,122,056 (+)NCBI
Rnor_6.0131,701,153 - 31,731,726 (+)NCBI
Rnor_5.0133,126,575 - 33,159,109 (+)NCBI
Sequence:
RefSeq Acc Id: NP_001020135   ⟸   NM_001024964
- UniProtKB: Q4QQU2 (UniProtKB/Swiss-Prot),   Q62825 (UniProtKB/Swiss-Prot),   A6JUV0 (UniProtKB/TrEMBL),   A0A8L2QA79 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006227829   ⟸   XM_006227767
- Peptide Label: isoform X1
- UniProtKB: Q4QQU2 (UniProtKB/Swiss-Prot),   Q62825 (UniProtKB/Swiss-Prot),   A6JUV0 (UniProtKB/TrEMBL),   A0A8L2QA79 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006227830   ⟸   XM_006227768
- Peptide Label: isoform X1
- UniProtKB: Q4QQU2 (UniProtKB/Swiss-Prot),   Q62825 (UniProtKB/Swiss-Prot),   A6JUV0 (UniProtKB/TrEMBL),   A0A8L2QA79 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000072705   ⟸   ENSRNOT00000077740
Ensembl Acc Id: ENSRNOP00000020251   ⟸   ENSRNOT00000020251

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q62825-F1-model_v2 AlphaFold Q62825 1-755 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13689557
Promoter ID:EPDNEW_R82
Type:multiple initiation site
Name:Exoc3_1
Description:exocyst complex component 3
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0131,700,938 - 31,700,998EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:621790 AgrOrtholog
BioCyc Gene G2FUF-61940 BioCyc
Ensembl Genes ENSRNOG00000039776 Ensembl, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000077740.2 UniProtKB/Swiss-Prot
Gene3D-CATH 1.10.357.50 UniProtKB/Swiss-Prot
  1.10.357.70 UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:7446619 IMAGE-MGC_LOAD
InterPro EXOC3/Sec6 UniProtKB/Swiss-Prot
  EXOC3/Sec6_C UniProtKB/Swiss-Prot
KEGG Report rno:252881 UniProtKB/Swiss-Prot
MGC_CLONE MGC:116137 IMAGE-MGC_LOAD
NCBI Gene 252881 ENTREZGENE
PANTHER EXOCYST COMPLEX COMPONENT 3 UniProtKB/Swiss-Prot
  PTHR21292 UniProtKB/Swiss-Prot
Pfam Sec6 UniProtKB/Swiss-Prot
PhenoGen Exoc3 PhenoGen
RatGTEx ENSRNOG00000039776 RatGTEx
UniProt A0A8L2QA79 ENTREZGENE, UniProtKB/TrEMBL
  A6JUV0 ENTREZGENE, UniProtKB/TrEMBL
  A6JUV2_RAT UniProtKB/TrEMBL
  EXOC3_RAT UniProtKB/Swiss-Prot
  Q4QQU2 ENTREZGENE
  Q62825 ENTREZGENE
UniProt Secondary Q4QQU2 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2006-03-30 Exoc3  exocyst complex component 3  Sec6l1  SEC6-like 1 (S. cerevisiae)  Symbol and Name updated 1299863 APPROVED
2004-09-10 Sec6l1  SEC6-like 1 (S. cerevisiae)  Sec6  RSec6 protein  Symbol and Name updated 1299863 APPROVED
2002-08-07 Sec6  RSec6 protein      Symbol and Name status set to provisional 70820 PROVISIONAL

RGD Curation Notes
Note Type Note Reference
gene_homology shows 22% amino acid identity to yeast Sec6p 633933
gene_protein 87-kDa protein 633933