Celsr3 (cadherin, EGF LAG seven-pass G-type receptor 3) - Rat Genome Database

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Pathways
Gene: Celsr3 (cadherin, EGF LAG seven-pass G-type receptor 3) Rattus norvegicus
Analyze
Symbol: Celsr3
Name: cadherin, EGF LAG seven-pass G-type receptor 3
RGD ID: 621787
Description: Predicted to enable G protein-coupled receptor activity and calcium ion binding activity. Predicted to be involved in Wnt signaling pathway, planar cell polarity pathway; axon guidance; and cell-cell adhesion mediated by cadherin. Predicted to act upstream of or within cilium assembly; generation of neurons; and regulation of protein localization. Predicted to be located in membrane. Predicted to be active in adherens junction; glutamatergic synapse; and synaptic membrane. Orthologous to human CELSR3 (cadherin EGF LAG seven-pass G-type receptor 3); INTERACTS WITH ammonium chloride; atrazine; bis(2-ethylhexyl) phthalate.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: cadherin EGF LAG seven-pass G-type receptor 3; cadherin, EGF LAG seven-pass G-type receptor 3 (flamingo homolog, Drosophila); Megf2; multiple EGF-like domains protein 2; multiple epidermal growth factor-like domains 2; multiple epidermal growth factor-like domains protein 2
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr88118,409,136 - 118,438,593 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl8118,409,136 - 118,436,847 (+)EnsemblGRCr8
mRatBN7.28109,530,597 - 109,558,360 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl8109,530,641 - 109,558,354 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx8115,148,091 - 115,175,780 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.08113,347,270 - 113,374,959 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.08111,190,068 - 111,217,758 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.08117,620,293 - 117,648,034 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl8117,620,317 - 117,648,028 (+)Ensemblrn6Rnor6.0
Rnor_5.08116,964,621 - 116,991,771 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.48113,882,883 - 113,923,950 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera8108,824,695 - 108,852,099 (+)NCBICelera
RGSC_v3.18113,902,337 - 113,943,405 (+)NCBI
Cytogenetic Map8q32NCBI
JBrowse:




Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,2,4-trichloro-5-(2,5-dichlorophenyl)benzene  (ISO)
1,2-dichloroethane  (ISO)
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (ISO)
2,2',4,4',5,5'-hexachlorobiphenyl  (ISO)
2,2',5,5'-tetrachlorobiphenyl  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (ISO)
2,4,4'-trichlorobiphenyl  (ISO)
2,4-D  (ISO)
2-methylcholine  (ISO)
4,4'-sulfonyldiphenol  (ISO)
Aflatoxin B2 alpha  (ISO)
aldehydo-D-glucose  (ISO)
all-trans-retinoic acid  (ISO)
ammonium chloride  (EXP)
aristolochic acid A  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
atrazine  (EXP)
benzo[a]pyrene  (ISO)
benzo[e]pyrene  (ISO)
bis(2-ethylhexyl) phthalate  (EXP)
bisphenol A  (EXP,ISO)
Butylbenzyl phthalate  (EXP)
cadmium dichloride  (EXP,ISO)
carbon nanotube  (ISO)
chlorpyrifos  (ISO)
choline  (ISO)
cisplatin  (ISO)
copper atom  (EXP)
copper(0)  (EXP)
D-glucose  (ISO)
DDE  (ISO)
dexamethasone  (ISO)
dibutyl phthalate  (EXP)
dicrotophos  (ISO)
diethyl phthalate  (EXP)
diisobutyl phthalate  (EXP)
Diisodecyl phthalate  (ISO)
diisononyl phthalate  (EXP)
dimethylarsinic acid  (EXP)
dorsomorphin  (ISO)
doxorubicin  (ISO)
emodin  (ISO)
ethanol  (ISO)
flavonoids  (EXP)
folic acid  (ISO)
fructose  (ISO)
furan  (EXP)
glucose  (ISO)
graphite  (EXP)
hydrogen peroxide  (ISO)
L-methionine  (ISO)
methapyrilene  (ISO)
niclosamide  (ISO)
paracetamol  (EXP)
PCB138  (ISO)
phenylmercury acetate  (ISO)
quercitrin  (ISO)
resveratrol  (ISO)
SB 431542  (ISO)
temozolomide  (ISO)
titanium dioxide  (ISO)
trichostatin A  (ISO)
triphenyl phosphate  (ISO)
triptonide  (ISO)
tunicamycin  (ISO)
valproic acid  (EXP,ISO)
XL147  (ISO)
zinc atom  (ISO)
zinc(0)  (ISO)

References

References - curated
# Reference Title Reference Citation
1. The flamingo-related mouse Celsr family (Celsr1-3) genes exhibit distinct patterns of expression during embryonic development. Formstone CJ and Little PF, Mech Dev 2001 Nov;109(1):91-4.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
4. Identification of high-molecular-weight proteins with multiple EGF-like motifs by motif-trap screening. Nakayama M, etal., Genomics 1998 Jul 1;51(1):27-34.
5. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
6. GOA pipeline RGD automated data pipeline
7. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
8. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
9. Complexes of matrilin-1 and biglycan or decorin connect collagen VI microfibrils to both collagen II and aggrecan. Wiberg C, etal., J Biol Chem 2003 Sep 26;278(39):37698-704.
Additional References at PubMed
PMID:15778712   PMID:17618280   PMID:20473291   PMID:20631168   PMID:21106844   PMID:24305805  


Genomics

Comparative Map Data
Celsr3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr88118,409,136 - 118,438,593 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl8118,409,136 - 118,436,847 (+)EnsemblGRCr8
mRatBN7.28109,530,597 - 109,558,360 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl8109,530,641 - 109,558,354 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx8115,148,091 - 115,175,780 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.08113,347,270 - 113,374,959 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.08111,190,068 - 111,217,758 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.08117,620,293 - 117,648,034 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl8117,620,317 - 117,648,028 (+)Ensemblrn6Rnor6.0
Rnor_5.08116,964,621 - 116,991,771 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.48113,882,883 - 113,923,950 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera8108,824,695 - 108,852,099 (+)NCBICelera
RGSC_v3.18113,902,337 - 113,943,405 (+)NCBI
Cytogenetic Map8q32NCBI
CELSR3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38348,636,463 - 48,662,886 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl348,636,463 - 48,662,886 (-)Ensemblhg38GRCh38
GRCh37348,673,896 - 48,700,319 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36348,648,900 - 48,675,352 (-)NCBIBuild 36Build 36hg18NCBI36
Build 34348,648,900 - 48,675,352NCBI
Celera348,629,806 - 48,656,257 (-)NCBICelera
Cytogenetic Map3p21.31NCBI
HuRef348,732,066 - 48,758,302 (-)NCBIHuRef
CHM1_1348,626,190 - 48,652,451 (-)NCBICHM1_1
T2T-CHM13v2.0348,665,423 - 48,691,846 (-)NCBIT2T-CHM13v2.0
Celsr3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm399108,703,244 - 108,730,168 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl9108,703,519 - 108,730,168 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm389108,826,023 - 108,852,969 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl9108,826,320 - 108,852,969 (+)Ensemblmm10GRCm38
MGSCv379108,728,651 - 108,755,300 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv369108,683,543 - 108,710,186 (+)NCBIMGSCv36mm8
Celera9108,433,487 - 108,460,140 (+)NCBICelera
Cytogenetic Map9F2NCBI
cM Map959.63NCBI
Celsr3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955532725,243 - 749,173 (-)Ensembl
ChiLan1.0NW_004955532724,306 - 749,192 (-)NCBIChiLan1.0ChiLan1.0
CELSR3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2248,610,805 - 48,639,012 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1348,615,573 - 48,643,236 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0348,557,976 - 48,586,051 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1349,639,936 - 49,667,335 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl349,639,942 - 49,667,335 (-)EnsemblpanPan2panpan1.1
CELSR3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12040,457,430 - 40,495,128 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2040,457,657 - 40,483,881 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha2040,375,514 - 40,412,346 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.02040,943,952 - 40,980,477 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2040,970,510 - 40,980,478 (+)EnsemblROS_Cfam_1.0 Ensembl
ROS_Cfam_1.0 Ensembl2040,943,706 - 40,966,371 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12040,181,313 - 40,217,932 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02040,585,605 - 40,622,438 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02040,867,118 - 40,903,641 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Celsr3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560263,676,979 - 63,703,515 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936529437,418 - 464,017 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_004936529437,476 - 464,012 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CELSR3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1331,331,574 - 31,357,469 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.11331,331,563 - 31,357,374 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21334,595,206 - 34,637,678 (-)NCBISscrofa10.2Sscrofa10.2susScr3
CELSR3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12210,046,361 - 10,073,689 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2210,045,900 - 10,072,395 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_023666041157,017,459 - 157,043,000 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Celsr3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247302,651,756 - 2,675,923 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046247302,650,096 - 2,675,930 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Celsr3
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v18100,157,973 - 100,184,768 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Celsr3
319 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:277
Count of miRNA genes:149
Interacting mature miRNAs:187
Transcripts:ENSRNOT00000040661
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2303171Bp331Blood pressure QTL 3315.570.005arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)8105462581132782436Rat
1549909Stresp11Stress response QTL 116.830.0019stress-related behavior trait (VT:0010451)number of approaches toward negative stimulus before onset of defensive burying response (CMO:0001960)882352698127352698Rat
631210Bw3Body weight QTL35.9mesenteric fat pad mass (VT:0010427)mesenteric fat pad weight to body weight ratio (CMO:0000654)861019838121662124Rat
1554321Bmd3Bone mineral density QTL 37.90.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)849849908118871671Rat
9590292Uminl3Urine mineral level QTL 33.620.001urine mineral amount (VT:0015086)urine electrolyte level (CMO:0000593)880768445125768445Rat
8694446Bw170Body weight QTL 17012.070.001retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)880768445125768445Rat
631650Stl6Serum triglyceride level QTL 640.0019blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)870041301121080908Rat
1581557Eae16Experimental allergic encephalomyelitis QTL 163.8nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)868690349119799881Rat
10450865Bw175Body weight QTL 1754.1total fat pad mass (VT:0015008)adipose tissue molecular composition measurement (CMO:0000484)884192326129192326Rat
724539Cm19Cardiac mass QTL 192.6heart mass (VT:0007028)calculated heart weight (CMO:0000073)8103375781129871912Rat
738011Anxrr9Anxiety related response QTL 96.1exploratory behavior trait (VT:0010471)number of entries into a discrete space in an experimental apparatus (CMO:0000960)8102413464132782436Rat
70197BpQTLcluster8Blood pressure QTL cluster 83.482arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)855428333127966348Rat
634332Pia18Pristane induced arthritis QTL 184joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)884192326132782436Rat
2300181Bmd55Bone mineral density QTL 555.70.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)885348065130348065Rat
1300171Bp184Blood pressure QTL 1843.66arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)879394435132782436Rat
2313400Anxrr25Anxiety related response QTL 25aggression-related behavior trait (VT:0015014)tameness/aggressiveness composite score (CMO:0002136)898145073122898010Rat
8694200Abfw4Abdominal fat weight QTL 49.070.001visceral adipose mass (VT:0010063)abdominal fat pad weight to body weight ratio (CMO:0000095)880768445125768445Rat
8694392Bw161Body weight QTL 1618.060.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)880768445125768445Rat
61437Cia6Collagen induced arthritis QTL 6joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)891340911131690273Rat

Markers in Region
BF386320  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.28109,528,642 - 109,528,814 (+)MAPPERmRatBN7.2
Rnor_6.08117,618,319 - 117,618,490NCBIRnor6.0
Rnor_5.08116,962,623 - 116,962,794UniSTSRnor5.0
RGSC_v3.48113,880,885 - 113,881,056UniSTSRGSC3.4
Celera8108,822,697 - 108,822,868UniSTS
RH 3.4 Map81115.79UniSTS
Cytogenetic Map8q32UniSTS
BF406162  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.28109,528,704 - 109,528,872 (+)MAPPERmRatBN7.2
Rnor_6.08117,618,381 - 117,618,548NCBIRnor6.0
Rnor_5.08116,962,685 - 116,962,852UniSTSRnor5.0
RGSC_v3.48113,880,947 - 113,881,114UniSTSRGSC3.4
Celera8108,822,759 - 108,822,926UniSTS
RH 3.4 Map81114.89UniSTS
Cytogenetic Map8q32UniSTS
Celsr3  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.28109,551,665 - 109,552,479 (+)MAPPERmRatBN7.2
Rnor_6.08117,641,340 - 117,642,153NCBIRnor6.0
Rnor_5.08116,985,078 - 116,985,891UniSTSRnor5.0
RGSC_v3.48113,917,263 - 113,918,076UniSTSRGSC3.4
Celera8108,845,413 - 108,846,226UniSTS
Cytogenetic Map8q32UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 9 62 155 61 59 34 37 34 6 225 127 9 136 40 91 25 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000084220   ⟹   ENSRNOP00000068821
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl8118,409,136 - 118,436,847 (+)Ensembl
mRatBN7.2 Ensembl8109,530,641 - 109,558,354 (+)Ensembl
Rnor_6.0 Ensembl8117,620,317 - 117,648,028 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000112823   ⟹   ENSRNOP00000079747
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl8118,409,136 - 118,436,847 (+)Ensembl
mRatBN7.2 Ensembl8109,530,641 - 109,558,354 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000118398   ⟹   ENSRNOP00000085264
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl8118,409,136 - 118,433,489 (+)Ensembl
mRatBN7.2 Ensembl8109,530,641 - 109,554,996 (+)Ensembl
RefSeq Acc Id: NM_031320   ⟹   NP_112610
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr88118,409,136 - 118,436,847 (+)NCBI
mRatBN7.28109,530,641 - 109,558,354 (+)NCBI
Rnor_6.08117,620,317 - 117,648,028 (+)NCBI
Rnor_5.08116,964,621 - 116,991,771 (+)NCBI
RGSC_v3.48113,882,883 - 113,923,950 (+)RGD
Celera8108,824,695 - 108,852,099 (+)RGD
Sequence:
RefSeq Acc Id: XM_006243860   ⟹   XP_006243922
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr88118,409,404 - 118,438,593 (+)NCBI
mRatBN7.28109,530,603 - 109,558,360 (+)NCBI
Rnor_6.08117,620,296 - 117,648,034 (+)NCBI
Rnor_5.08116,964,621 - 116,991,771 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006243861   ⟹   XP_006243923
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr88118,409,404 - 118,429,365 (+)NCBI
mRatBN7.28109,530,603 - 109,550,732 (+)NCBI
Rnor_6.08117,620,293 - 117,640,496 (+)NCBI
Rnor_5.08116,964,621 - 116,991,771 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039082204   ⟹   XP_038938132
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr88118,409,404 - 118,438,593 (+)NCBI
mRatBN7.28109,530,603 - 109,558,360 (+)NCBI
RefSeq Acc Id: XM_039082205   ⟹   XP_038938133
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr88118,409,404 - 118,438,593 (+)NCBI
mRatBN7.28109,530,603 - 109,558,360 (+)NCBI
RefSeq Acc Id: XM_063266218   ⟹   XP_063122288
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr88118,409,404 - 118,429,853 (+)NCBI
RefSeq Acc Id: XR_005487934
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr88118,409,404 - 118,422,390 (+)NCBI
mRatBN7.28109,530,597 - 109,543,898 (+)NCBI
RefSeq Acc Id: XR_005487935
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr88118,409,404 - 118,424,282 (+)NCBI
mRatBN7.28109,530,597 - 109,545,787 (+)NCBI
RefSeq Acc Id: XR_010054036
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr88118,409,404 - 118,430,209 (+)NCBI
RefSeq Acc Id: NP_112610   ⟸   NM_031320
- Peptide Label: precursor
- UniProtKB: O88278 (UniProtKB/Swiss-Prot),   A0A8L2R1D5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006243922   ⟸   XM_006243860
- Peptide Label: isoform X1
- UniProtKB: A0A8L2R1D5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006243923   ⟸   XM_006243861
- Peptide Label: isoform X5
- UniProtKB: A6I391 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000068821   ⟸   ENSRNOT00000084220
RefSeq Acc Id: XP_038938132   ⟸   XM_039082204
- Peptide Label: isoform X2
- UniProtKB: A0A8L2R1D5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038938133   ⟸   XM_039082205
- Peptide Label: isoform X3
- UniProtKB: A0A8L2R1D5 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000085264   ⟸   ENSRNOT00000118398
Ensembl Acc Id: ENSRNOP00000079747   ⟸   ENSRNOT00000112823
RefSeq Acc Id: XP_063122288   ⟸   XM_063266218
- Peptide Label: isoform X4
- UniProtKB: A6I391 (UniProtKB/TrEMBL)
Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:621787 AgrOrtholog
BioCyc Gene G2FUF-29112 BioCyc
Ensembl Genes ENSRNOG00000053889 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000084220 ENTREZGENE
  ENSRNOT00000112823.1 UniProtKB/Swiss-Prot
Gene3D-CATH 2.60.120.200 UniProtKB/Swiss-Prot
  2.60.220.50 UniProtKB/Swiss-Prot
  4.10.1240.10 UniProtKB/Swiss-Prot
  Cadherins UniProtKB/Swiss-Prot
  Laminin UniProtKB/Swiss-Prot
  Rhodopsin 7-helix transmembrane proteins UniProtKB/Swiss-Prot
InterPro Cadherin-like_dom UniProtKB/Swiss-Prot
  Cadherin-like_sf UniProtKB/Swiss-Prot
  Cadherin_CELSR1-3_9th UniProtKB/Swiss-Prot
  Cadherin_CS UniProtKB/Swiss-Prot
  ConA-like_dom_sf UniProtKB/Swiss-Prot
  EGF-like_Ca-bd_dom UniProtKB/Swiss-Prot
  EGF-like_dom UniProtKB/Swiss-Prot
  GAIN_B UniProtKB/Swiss-Prot
  GAIN_dom_N UniProtKB/Swiss-Prot
  GAIN_dom_sf UniProtKB/Swiss-Prot
  GPCR_2-like UniProtKB/Swiss-Prot
  GPCR_2_extracell_dom_sf UniProtKB/Swiss-Prot
  GPCR_2_extracellular_dom UniProtKB/Swiss-Prot
  GPCR_2_secretin-like UniProtKB/Swiss-Prot
  GPCR_2_secretin-like_CS UniProtKB/Swiss-Prot
  GPS UniProtKB/Swiss-Prot
  Laminin_EGF UniProtKB/Swiss-Prot
  Laminin_G UniProtKB/Swiss-Prot
KEGG Report rno:83466 UniProtKB/Swiss-Prot
NCBI Gene 83466 ENTREZGENE
PANTHER CADHERIN EGF LAG SEVEN-PASS G-TYPE RECEPTOR 3 UniProtKB/Swiss-Prot
  FAT ATYPICAL CADHERIN-RELATED UniProtKB/Swiss-Prot
Pfam 7tm_2 UniProtKB/Swiss-Prot
  Cadherin UniProtKB/Swiss-Prot
  Cadherin_CELSR2_9th UniProtKB/Swiss-Prot
  EGF UniProtKB/Swiss-Prot
  GAIN UniProtKB/Swiss-Prot
  GPS UniProtKB/Swiss-Prot
  HRM UniProtKB/Swiss-Prot
  Laminin_EGF UniProtKB/Swiss-Prot
  Laminin_G_2 UniProtKB/Swiss-Prot
PhenoGen Celsr3 PhenoGen
PRINTS CADHERIN UniProtKB/Swiss-Prot
  GPCRSECRETIN UniProtKB/Swiss-Prot
PROSITE ASX_HYDROXYL UniProtKB/Swiss-Prot
  CADHERIN_1 UniProtKB/Swiss-Prot
  CADHERIN_2 UniProtKB/Swiss-Prot
  EGF_1 UniProtKB/Swiss-Prot
  EGF_2 UniProtKB/Swiss-Prot
  EGF_3 UniProtKB/Swiss-Prot
  EGF_LAM_1 UniProtKB/Swiss-Prot
  EGF_LAM_2 UniProtKB/Swiss-Prot
  G_PROTEIN_RECEP_F2_2 UniProtKB/Swiss-Prot
  G_PROTEIN_RECEP_F2_3 UniProtKB/Swiss-Prot
  G_PROTEIN_RECEP_F2_4 UniProtKB/Swiss-Prot
  GPS UniProtKB/Swiss-Prot
  LAM_G_DOMAIN UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000053889 RatGTEx
SMART EGF UniProtKB/Swiss-Prot
  EGF_CA UniProtKB/Swiss-Prot
  EGF_Lam UniProtKB/Swiss-Prot
  GPS UniProtKB/Swiss-Prot
  HormR UniProtKB/Swiss-Prot
  LamG UniProtKB/Swiss-Prot
  SM00112 UniProtKB/Swiss-Prot
Superfamily-SCOP EGF/Laminin UniProtKB/Swiss-Prot
  SSF111418 UniProtKB/Swiss-Prot
  SSF49313 UniProtKB/Swiss-Prot
  SSF49899 UniProtKB/Swiss-Prot
UniProt A0A8I6A2Y0_RAT UniProtKB/TrEMBL
  A0A8L2R1D5 ENTREZGENE, UniProtKB/TrEMBL
  A6I391 ENTREZGENE, UniProtKB/TrEMBL
  CELR3_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2013-02-27 Celsr3  cadherin, EGF LAG seven-pass G-type receptor 3  Celsr3  cadherin, EGF LAG seven-pass G-type receptor 3 (flamingo homolog, Drosophila)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-25 Celsr3  cadherin, EGF LAG seven-pass G-type receptor 3 (flamingo homolog, Drosophila)  Celsr3  cadherin EGF LAG seven-pass G-type receptor 3  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-01-20 Celsr3  cadherin EGF LAG seven-pass G-type receptor 3      Symbol and Name status set to approved 1299863 APPROVED
2002-08-07 Celsr3  cadherin EGF LAG seven-pass G-type receptor 3      Symbol and Name status set to provisional 70820 PROVISIONAL

RGD Curation Notes
Note Type Note Reference
gene_domains contains multiple EGF-like motifs 68762