Gene:	Csnk2a1 ( Rattus norvegicus ) casein kinase 2, alpha 1 polypeptide
Description:	alpha subunit of casein kinase II, a protein serine/threonine kinase that may play a role in regulation of cell growth and proliferation
Synonyms:	casein kinase II, alpha 1 polypeptide; casein kinase ii, alpha 1 polypeptide;  (details...)
ArrayIDs:	1375636_at; 5728867; 1387170_at; 5830796; 1384339_s_at; 1392650_at; 6532133; 6603514; L15618_at; A_43_P12945; 6014171; A_44_P363204; 6686126; 5790618; 5726014; rc_AI012245_at; 1389974_at; 6405563; 6001028; 6482833; rc_AI072089_at; 5799266; 5823549; 5657052; rc_AA875506_at; rc_AI103003_s_at; 6601255; 6086792; 6199507; 6634360; rc_AI179620_at; 6292374; 6724816;  (details...)
Gene Type:	protein-coding
Additional Data
Homologs
Homo sapiens: CSNK2A1     See the Human gene in context in:     UCSC     NCBI MapViewer
Mus musculus: Csnk2a1     See the Mouse gene in context in:     UCSC     NCBI MapViewer
Comparative Map Data Species Symbol Map Name Chr. Position Rattus norvegicus Csnk2a1 genome assembly 3.1 3 142470349 - 142514931     Rat Celera Assembly 3 139485716 - 139506506     RGSC genome assembly v3.4 3 142564777 - 142609358     Cytogenetic 3 q41 Mus musculus Csnk2a1 Mouse genome assembly build 36.1 2 152052687 - 152107583     Cytogenetic 2 2 G3 Homo sapiens CSNK2A1 human genome assembly 20 411337 - 472482     Human genome assembly build 36.2 20 411338 - 472482     Cytogenetic 20 p13   View comparative maps:      NCBI MapViewer
Genome
View:
Browsers:	Select a browser to viewGene (GBrowse)Gene and SNPs (GBrowse)UCSCVCMAPEnsemblNCBIECRVISTAVISTA+UCSC
Annotation
Molecular Function	Gene Ontology protein N-terminus binding,  protein phosphatase regulator activity,  nucleotide binding ...  (details...)
Biological Process	Gene Ontology protein amino acid autophosphorylation,  regulation of cell growth,  protein amino acid phosphorylation ...  (details...)
Cellular Component	Gene Ontology protein kinase CK2 complex,  NuRD complex,  Sin3 complex (details...)
Regulation	Note Reference transcription is regulated by androgen, regulation is not an early androgen response but occurs in later stages of androgen mediated cell proliferation 727982
External Links
Databases	DATABASE ID SOURCE SMART: S_TKc IPI PROSITE: PROTEIN_KINASE_DOM IPI PROSITE: PROTEIN_KINASE_ATP IPI PROSITE: PROTEIN_KINASE_ST IPI UNIPARC: UPI0000D77971 IPI UNIPARC: UPI000012DC6C IPI KEGG Report: rno:116549 ENTREZGENE HomoloGene Group ID: 90874 ENTREZGENE Germonline: 621663 Pfam: Pkinase IPI KEGG Pathway: 04310 ENTREZGENE KEGG Pathway: 04520 ENTREZGENE KEGG Pathway: 04530 ENTREZGENE InterPro: Protein_kinase_ATP_BS. IPI InterPro: Kinase-like_dom. IPI InterPro: Prot_kinase_cat_dom. IPI InterPro: Se/Thr_prot_kinase-like_dom. IPI InterPro: Ser/Thr_prot_kinase_AS. IPI InterPro: Ser/Thr_prot_kinase_dom. IPI IPI: IPI00192586 IPI IPI: IPI00947824 IPI Ensembl Protein: ENSRNOP00000007558 IPI Ensembl Protein: ENSRNOP00000059475 IPI Entrez Gene: Csnk2a1 ENTREZGENE IMAGE_CLONE: IMAGE:7367296 IMAGE-MGC_LOAD MGC_CLONE: MGC:108626 IMAGE-MGC_LOAD UniProt: CSK21_RAT IPI Ensembl Genes: ENSRNOG00000005276 IPI Superfamily-SCOP: Kinase_like IPI
Sequences	Nucleotide: CH474050 Get FASTA Search GEO Profiles Nucleotide: BC091130 Get FASTA Search GEO Profiles Nucleotide: NM_053824 Get FASTA Search GEO Profiles Nucleotide: L15618 Get FASTA Search GEO Profiles (View all 4 Nucleotide Accessions) Protein: AAA74462 Get FASTA Protein: AAH91130 Get FASTA Protein: EDL86080 Get FASTA Protein: NP_446276 Get FASTA Protein: P19139 Get FASTA (View all 5 Protein Accessions)
Clusters	UniGene: 4231
References
Curated References	5 references in RGD related to Csnk2a1
Other References	5 other references at PubMed related to Csnk2a1
Database Information
RGD ID	621663
History	Date Current Symbol Current Name Previous Symbol Previous name Status Description Reference 25-FEB-08: Csnk2a1 casein kinase 2, alpha 1 polypeptide Csnk2a1 casein kinase II, alpha 1 polypeptide APPROVED Nomenclature updated to reflect human and mouse nomenclature 1299863 20-JAN-05: Csnk2a1 casein kinase II, alpha 1 polypeptide APPROVED Symbol and Name status set to approved 1299863 07-AUG-02: Csnk2a1 casein kinase II, alpha 1 polypeptide PROVISIONAL Symbol and Name status set to provisional 70820