Wnt11 (Wnt family member 11) - Rat Genome Database

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Gene: Wnt11 (Wnt family member 11) Rattus norvegicus
Analyze
Symbol: Wnt11
Name: Wnt family member 11
RGD ID: 621463
Description: Predicted to enable cytokine activity; frizzled binding activity; and protein kinase activator activity. Involved in cell differentiation and response to nutrient levels. Predicted to be located in cytoplasm; extracellular matrix; and extracellular region. Predicted to be active in extracellular space. Human ortholog(s) of this gene implicated in oral squamous cell carcinoma. Orthologous to human WNT11 (Wnt family member 11); PARTICIPATES IN the Wnt/calcium signaling pathway; Wnt signaling pathway; Wnt signaling, canonical pathway; INTERACTS WITH 6-propyl-2-thiouracil; alpha-Zearalanol; ammonium chloride.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: wingless-related MMTV integration site 11; wingless-type MMTV integration site family, member 11
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81162,545,660 - 162,565,456 (+)NCBIGRCr8
mRatBN7.21153,134,503 - 153,154,294 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1153,138,197 - 153,154,294 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1161,133,836 - 161,149,936 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01168,314,007 - 168,330,107 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01161,187,522 - 161,203,622 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01163,794,136 - 163,813,756 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1163,797,660 - 163,813,756 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01169,997,286 - 170,016,829 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41156,125,969 - 156,142,065 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11156,213,816 - 156,216,652 (+)NCBI
Celera1151,224,671 - 151,240,729 (+)NCBICelera
Cytogenetic Map1q32NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model



  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Wnt11Ratoral squamous cell carcinoma susceptibilityISOWNT11 (Homo sapiens)150530486DNA:SNP:exon: A>G (rs1533767) (human)RGD 
Wnt11RatProstatic Neoplasms disease_progressionISOWNT11 (Homo sapiens)2299946 RGD 
Wnt11Ratrenal cell carcinoma  ISOWNT11 (Homo sapiens)2299947 RGD 
Object Symbol
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Original Reference(s)
Wnt11Ratbladder exstrophy-epispadias-cloacal exstrophy complex  ISOWNT11 (Homo sapiens)8554872ClinVar Annotator: match by term: Bladder exstrophy-epispadias-cloacal exstrophy complexClinVarPMID:25741868
Wnt11Rathypospadias  ISOWNT11 (Homo sapiens)8554872ClinVar Annotator: match by term: HypospadiasClinVarPMID:25741868
Wnt11Ratintellectual disability  ISOWNT11 (Homo sapiens)8554872ClinVar Annotator: match by term: Intellectual disabilityClinVar 
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Original Reference(s)
Wnt11RatAbnormalities, Drug-Induced  ISOWNT11 (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:25783350
Wnt11RatAnimal Disease Models  ISOWNT11 (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:25783350
Wnt11Ratcongenital diaphragmatic hernia  ISOWNT11 (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:25783350

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Original Reference(s)
Wnt11Rat17beta-estradiol decreases expressionISOWnt11 (Mus musculus)6480464Estradiol results in decreased expression of WNT11 mRNACTDPMID:23144751
Wnt11Rat2,3,7,8-tetrachlorodibenzodioxine increases expressionISOWNT11 (Homo sapiens)6480464Tetrachlorodibenzodioxin results in increased expression of WNT11 mRNACTDPMID:20106945 more ...
Wnt11Rat2,3,7,8-tetrachlorodibenzodioxine affects expressionISOWnt11 (Mus musculus)6480464Tetrachlorodibenzodioxin affects the expression of WNT11 mRNACTDPMID:21570461
Wnt11Rat2,4-dibromophenyl 2,4,5-tribromophenyl ether affects expressionISOWnt11 (Mus musculus)64804642 more ...CTDPMID:38648751
Wnt11Rat3-isobutyl-1-methyl-7H-xanthine multiple interactionsISOWNT11 (Homo sapiens)6480464[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in increased expression of WNT11 mRNACTDPMID:28628672
Wnt11Rat4,4'-sulfonyldiphenol decreases expressionISOWNT11 (Homo sapiens)6480464bisphenol S results in decreased expression of WNT11 mRNACTDPMID:27685785
Wnt11Rat4,4'-sulfonyldiphenol increases expressionISOWnt11 (Mus musculus)6480464bisphenol S results in increased expression of WNT11 mRNACTDPMID:30951980
Wnt11Rat4-hydroperoxycyclophosphamide increases expressionISOWnt11 (Mus musculus)6480464perfosfamide results in increased expression of WNT11 mRNACTDPMID:19429390
Wnt11Rat6-propyl-2-thiouracil increases expressionEXP 6480464Propylthiouracil results in increased expression of WNT11 mRNACTDPMID:24780913
Wnt11Rataflatoxin B1 increases methylationISOWNT11 (Homo sapiens)6480464Aflatoxin B1 results in increased methylation of WNT11 geneCTDPMID:27153756
Wnt11Ratall-trans-retinoic acid increases expressionISOWnt11 (Mus musculus)6480464Tretinoin results in increased expression of WNT11 mRNACTDPMID:36189433
Wnt11Ratalpha-Zearalanol increases expressionEXP 6480464Zeranol results in increased expression of WNT11 mRNACTDPMID:35163327
Wnt11Ratammonium chloride affects expressionEXP 6480464Ammonium Chloride affects the expression of WNT11 mRNACTDPMID:16483693
Wnt11Ratamosite asbestos decreases methylationISOWNT11 (Homo sapiens)6480464Asbestos and Amosite results in decreased methylation of WNT11 promoterCTDPMID:29626692
Wnt11Ratamphetamine increases expressionEXP 6480464Amphetamine results in increased expression of WNT11 mRNACTDPMID:30779732
Wnt11Ratantirheumatic drug increases expressionISOWNT11 (Homo sapiens)6480464Antirheumatic Agents results in increased expression of WNT11 mRNACTDPMID:24449571
Wnt11RatAroclor 1254 increases expressionISOWnt11 (Mus musculus)6480464Chlorodiphenyl (54% Chlorine) results in increased expression of WNT11 mRNACTDPMID:23650126
Wnt11Ratarsane affects methylationISOWNT11 (Homo sapiens)6480464Arsenic affects the methylation of WNT11 geneCTDPMID:25304211
Wnt11Ratarsenic atom affects methylationISOWNT11 (Homo sapiens)6480464Arsenic affects the methylation of WNT11 geneCTDPMID:25304211
Wnt11Ratbenzo[a]pyrene increases expressionISOWNT11 (Homo sapiens)6480464Benzo(a)pyrene results in increased expression of WNT11 mRNACTDPMID:20106945 more ...

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Biological Process
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Original Reference(s)
Wnt11Ratadrenal gland development involved_inISOWNT11 (Homo sapiens)1624291 PMID:9757009RGDPMID:9757009
Wnt11Ratadrenal gland development involved_inIEAUniProtKB:O96014 and ensembl:ENSP000003255261600115GO_REF:0000107EnsemblGO_REF:0000107
Wnt11Ratapoptotic process acts_upstream_ofISOWnt11 (Mus musculus)1624291 PMID:18191119RGDPMID:18191119
Wnt11Ratapoptotic process acts_upstream_ofIEAUniProtKB:P48615 and ensembl:ENSMUSP000000643331600115GO_REF:0000107EnsemblGO_REF:0000107
Wnt11Ratartery morphogenesis acts_upstream_of_or_withinISOWnt11 (Mus musculus)1624291MGI:2665014 PMID:17767158RGDPMID:17767158
Wnt11Ratartery morphogenesis acts_upstream_of_or_withinIEAUniProtKB:P48615 and ensembl:ENSMUSP000000643331600115GO_REF:0000107EnsemblGO_REF:0000107
Wnt11Ratatrial septum development involved_inISOWnt11 (Mus musculus)1624291UniProtKB:P22725 and PMID:22569553RGDPMID:22569553
Wnt11Ratatrial septum development involved_inIEAUniProtKB:P48615 and ensembl:ENSMUSP000000643331600115GO_REF:0000107EnsemblGO_REF:0000107
Wnt11Ratbicellular tight junction assembly acts_upstream_of_or_withinISOWnt11 (Mus musculus)1624291MGI:2665014 PMID:17767158RGDPMID:17767158
Wnt11Ratbicellular tight junction assembly acts_upstream_of_or_withinIEAUniProtKB:P48615 and ensembl:ENSMUSP000000643331600115GO_REF:0000107EnsemblGO_REF:0000107
Wnt11Ratbone mineralization acts_upstream_of_or_withinISOWnt11 (Mus musculus)1624291MGI:88177 PMID:19213727RGDPMID:19213727
Wnt11Ratbone mineralization acts_upstream_of_or_withinIEAUniProtKB:P48615 and ensembl:ENSMUSP000000643331600115GO_REF:0000107EnsemblGO_REF:0000107
Wnt11Ratcanonical Wnt signaling pathway acts_upstream_of_or_withinISOWnt11 (Mus musculus)1624291 PMID:19213727RGDPMID:19213727
Wnt11Ratcanonical Wnt signaling pathway acts_upstream_of_or_withinIEAUniProtKB:P48615 and ensembl:ENSMUSP000000643331600115GO_REF:0000107EnsemblGO_REF:0000107
Wnt11Ratcanonical Wnt signaling pathway involved_inIBAFB:FBgn0004360 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Wnt11Ratcell differentiation  IEP 2317898 RGD 
Wnt11Ratcell fate commitment involved_inIBAFB:FBgn0284084 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Wnt11Ratcellular response to mechanical stimulus acts_upstream_of_or_withinIEAUniProtKB:P48615 and ensembl:ENSMUSP000000643331600115GO_REF:0000107EnsemblGO_REF:0000107
Wnt11Ratcellular response to mechanical stimulus acts_upstream_of_or_withinISOWnt11 (Mus musculus)1624291 PMID:25959411RGDPMID:25959411
Wnt11Ratcloacal septation involved_inISOWNT11 (Homo sapiens)1624291 PMID:9757009RGDPMID:9757009
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Cellular Component
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Original Reference(s)
Wnt11Ratcytoplasm located_inISOWNT11 (Homo sapiens)1624291 PMID:20103596 and PMID:20219091RGDPMID:20103596 and PMID:20219091
Wnt11Ratcytoplasm located_inIEAUniProtKB:O96014 and ensembl:ENSP000003255261600115GO_REF:0000107EnsemblGO_REF:0000107
Wnt11Ratextracellular matrix located_inISOWnt11 (Mus musculus)1624291 PMID:8700530RGDPMID:8700530
Wnt11Ratextracellular matrix located_inIEAUniProtKB:P48615 and ensembl:ENSMUSP000000643331600115GO_REF:0000107EnsemblGO_REF:0000107
Wnt11Ratextracellular region located_inIEAUniProtKB:P48615 and ensembl:ENSMUSP000000643331600115GO_REF:0000107EnsemblGO_REF:0000107
Wnt11Ratextracellular region located_inIEAInterPro:IPR0058171600115GO_REF:0000002InterProGO_REF:0000002
Wnt11Ratextracellular region located_inISOWnt11 (Mus musculus)1624291 PMID:18155657RGDPMID:18155657
Wnt11Ratextracellular region located_inIEAUniProtKB-KW:KW-09641600115GO_REF:0000043UniProtGO_REF:0000043
Wnt11Ratextracellular space is_active_inIBAFB:FBgn0284084 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
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Molecular Function

  
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Original Reference(s)
Wnt11Ratcytokine activity enablesIBAMGI:98953 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Wnt11Ratfrizzled binding enablesIBAFB:FBgn0004360 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Wnt11Ratprotein binding enablesISOWNT11 (Homo sapiens)1624291UniProtKB:A6NK89 more ...RGDPMID:25416956 more ...
Wnt11Ratprotein binding enablesISOWnt11 (Mus musculus)1624291PR:Q9D1D6 PMID:18606138RGDPMID:18606138
Wnt11Ratprotein kinase activator activity enablesISOWNT11 (Homo sapiens)1624291 PMID:20219091RGDPMID:20219091
Wnt11Ratprotein kinase activator activity enablesIEAUniProtKB:O96014 and ensembl:ENSP000003255261600115GO_REF:0000107EnsemblGO_REF:0000107
Wnt11Ratsignaling receptor binding enablesIEAInterPro:IPR0058171600115GO_REF:0000002InterProGO_REF:0000002

RGD Manual Annotations


  

Imported Annotations - KEGG (archival)

Object Symbol
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Original Reference(s)
Wnt11Ratbasal cell carcinoma pathway  IEA 6907045 KEGGrno:05217
Wnt11RatHedgehog signaling pathway   IEA 6907045 KEGGrno:04340
Wnt11RatWnt signaling pathway  IEA 6907045 KEGGrno:04310

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Reference Title
Reference Citation
1. Mechanisms of impaired nephrogenesis with fetal growth restriction: altered renal transcription and growth factor expression. Abdel-Hakeem AK, etal., Am J Obstet Gynecol. 2008 Sep;199(3):252.e1-7. Epub 2008 Jul 17.
2. Insights from studies with oral cleft genes suggest associations between WNT-pathway genes and risk of oral cancer. Andrade Filho PA, etal., J Dent Res. 2011 Jun;90(6):740-6. doi: 10.1177/0022034511401622. Epub 2011 Mar 10.
3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
4. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
5. Molecular cloning and characterization of human WNT11. Kirikoshi H, etal., Int J Mol Med. 2001 Dec;8(6):651-6.
6. Wnt signal pathways and neural stem cell differentiation. Lange C, etal., Neurodegener Dis. 2006;3(1-2):76-86.
7. Wnt11 and Ret/Gdnf pathways cooperate in regulating ureteric branching during metanephric kidney development. Majumdar A, etal., Development 2003 Jul;130(14):3175-85.
8. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
9. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
10. Wnt11 signaling promotes proliferation, transformation, and migration of IEC6 intestinal epithelial cells. Ouko L, etal., J Biol Chem 2004 Jun 18;279(25):26707-15. Epub 2004 Apr 14.
11. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
12. GOA pipeline RGD automated data pipeline
13. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
14. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
15. Comprehensive gene review and curation RGD comprehensive gene curation
16. Wnt signaling in the ovary: identification and compartmentalized expression of wnt-2, wnt-2b, and frizzled-4 mRNAs. Ricken A, etal., Endocrinology 2002 Jul;143(7):2741-9.
17. The Wnt Homepage Roel Nusse - Howard Hughes Medical Institute and the Department of Developmental Biology at Stanford University, California, USA
18. Alternative wnt signaling is initiated by distinct receptors. van Amerongen R, etal., Sci Signal. 2008 Sep 2;1(35):re9.
19. Analysis of Wnt gene expression in prostate cancer: mutual inhibition by WNT11 and the androgen receptor. Zhu H, etal., Cancer Res. 2004 Nov 1;64(21):7918-26.
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PMID:8700530   PMID:9757009   PMID:17767158   PMID:18155657   PMID:18191119   PMID:18413325   PMID:19213727   PMID:19847889   PMID:20103596   PMID:20219091   PMID:21281623   PMID:22569553  
PMID:22829700   PMID:22985995   PMID:23998262   PMID:24474615   PMID:25813538   PMID:25959411   PMID:26193266   PMID:33137935  



Wnt11
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81162,545,660 - 162,565,456 (+)NCBIGRCr8
mRatBN7.21153,134,503 - 153,154,294 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1153,138,197 - 153,154,294 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1161,133,836 - 161,149,936 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01168,314,007 - 168,330,107 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01161,187,522 - 161,203,622 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01163,794,136 - 163,813,756 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1163,797,660 - 163,813,756 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01169,997,286 - 170,016,829 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41156,125,969 - 156,142,065 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11156,213,816 - 156,216,652 (+)NCBI
Celera1151,224,671 - 151,240,729 (+)NCBICelera
Cytogenetic Map1q32NCBI
WNT11
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381176,186,325 - 76,210,761 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1176,186,325 - 76,210,736 (-)EnsemblGRCh38hg38GRCh38
GRCh371175,897,369 - 75,917,546 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361175,575,018 - 75,595,222 (-)NCBINCBI36Build 36hg18NCBI36
Build 341175,575,017 - 75,595,222NCBI
Celera1173,205,187 - 73,225,391 (-)NCBICelera
Cytogenetic Map11q13.5NCBI
HuRef1172,194,546 - 72,214,753 (-)NCBIHuRef
CHM1_11175,780,888 - 75,801,091 (-)NCBICHM1_1
T2T-CHM13v2.01176,116,041 - 76,140,519 (-)NCBIT2T-CHM13v2.0
Wnt11
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39798,484,293 - 98,503,954 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl798,484,319 - 98,504,402 (+)EnsemblGRCm39 Ensembl
GRCm38798,835,084 - 98,854,747 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl798,835,112 - 98,855,195 (+)EnsemblGRCm38mm10GRCm38
MGSCv377105,987,355 - 106,003,257 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36798,714,037 - 98,728,940 (+)NCBIMGSCv36mm8
Celera799,160,445 - 99,176,286 (+)NCBICelera
Cytogenetic Map7E1NCBI
cM Map753.9NCBI
Wnt11
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541415,674,940 - 15,694,883 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495541415,674,478 - 15,694,758 (+)NCBIChiLan1.0ChiLan1.0
WNT11
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2977,110,987 - 77,161,434 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11178,156,064 - 78,180,195 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01171,239,781 - 71,263,915 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11174,540,025 - 74,560,024 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1174,540,169 - 74,560,024 (-)Ensemblpanpan1.1panPan2
WNT11
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12122,442,496 - 22,463,040 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2122,446,051 - 22,463,173 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2122,210,200 - 22,227,251 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02122,648,822 - 22,665,821 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2122,648,814 - 22,665,904 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12122,423,226 - 22,440,217 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02122,642,741 - 22,659,738 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02122,561,731 - 22,578,745 (+)NCBIUU_Cfam_GSD_1.0
Wnt11
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494763,309,313 - 63,329,371 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364984,908,978 - 4,927,165 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364984,909,041 - 4,927,482 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
WNT11
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl910,413,263 - 10,435,100 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1910,413,182 - 10,435,158 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2911,487,189 - 11,509,672 (+)NCBISscrofa10.2Sscrofa10.2susScr3
WNT11
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1167,393,975 - 67,427,247 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl167,399,074 - 67,418,509 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604358,377,747 - 58,402,147 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Wnt11
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624817932,970 - 952,326 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624817931,686 - 952,474 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

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Variants in Wnt11
72 total Variants

Predicted Target Of
Summary Value
Count of predictions:355
Count of miRNA genes:194
Interacting mature miRNAs:245
Transcripts:ENSRNOT00000021674
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


1 to 10 of 70 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
61442Strs1Sensitivity to stroke QTL 17.4cerebrum integrity trait (VT:0010549)post-insult time to onset of cerebrovascular lesion (CMO:0002343)1121767634166767634Rat
1578778Pur4Proteinuria QTL 43.30.003urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)1150700247252085048Rat
1354646Kidm18Kidney mass QTL 185.7kidney mass (VT:0002707)calculated kidney weight (CMO:0000160)1151162512256448636Rat
1578780Cm52Cardiac mass QTL 523.30.0001heart mass (VT:0007028)heart wet weight (CMO:0000069)181591954219808434Rat
1578654Bss10Bone structure and strength QTL 104femur morphology trait (VT:0000559)femoral neck cortical cross-sectional area (CMO:0001702)149393172159356837Rat
2302378Insul11Insulin level QTL 113.25blood insulin amount (VT:0001560)serum insulin level (CMO:0000358)1144267353251128347Rat
1598866Bp287Blood pressure QTL 2875.1arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1121006655166006655Rat
1578770Stresp23Stress response QTL 23kidney sympathetic nerve activity (VT:0004050)stimulated renal sympathetic nerve activity to basal renal sympathetic nerve activity ratio (CMO:0001786)1123350408182418476Rat
70160Bw18Body weight QTL 185.7body mass (VT:0001259)body weight (CMO:0000012)1144267353196383668Rat
7794788Mcs32Mammary carcinoma susceptibility QTL 322.61mammary gland integrity trait (VT:0010552)mammary tumor incidence/prevalence measurement (CMO:0000946)1115540693238914717Rat

1 to 10 of 70 rows
D1Mgh8  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr81162,548,015 - 162,548,132 (+)Marker Load Pipeline
mRatBN7.21153,136,852 - 153,136,969 (+)MAPPERmRatBN7.2
Rnor_6.01163,796,316 - 163,796,432NCBIRnor6.0
Rnor_5.01169,999,389 - 169,999,505UniSTSRnor5.0
RGSC_v3.41156,124,624 - 156,124,741RGDRGSC3.4
RGSC_v3.41156,124,625 - 156,124,741UniSTSRGSC3.4
RGSC_v3.11156,203,030 - 156,203,147RGD
Celera1151,223,327 - 151,223,443UniSTS
RH 3.4 Map11215.0RGD
RH 3.4 Map11215.0UniSTS
RH 2.0 Map1788.6RGD
Cytogenetic Map1q32UniSTS
RP_L27  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21153,154,521 - 153,154,640 (+)MAPPERmRatBN7.2
Rnor_6.01163,813,984 - 163,814,102NCBIRnor6.0
Rnor_5.01170,017,057 - 170,017,175UniSTSRnor5.0
RGSC_v3.41156,142,293 - 156,142,411UniSTSRGSC3.4
Celera1151,240,957 - 151,241,075UniSTS
Cytogenetic Map1q32UniSTS
UniSTS:471854  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21153,145,737 - 153,145,942 (+)MAPPERmRatBN7.2
Rnor_6.01163,805,200 - 163,805,404NCBIRnor6.0
Rnor_5.01170,008,273 - 170,008,477UniSTSRnor5.0
RGSC_v3.41156,133,509 - 156,133,713UniSTSRGSC3.4
Celera1151,232,211 - 151,232,415UniSTS
Cytogenetic Map1q32UniSTS




alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 71 70 39 25 39 6 198 97 93 45 60 31



Ensembl Acc Id: ENSRNOT00000021674   ⟹   ENSRNOP00000021674
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1153,138,197 - 153,154,294 (+)Ensembl
Rnor_6.0 Ensembl1163,797,660 - 163,813,756 (+)Ensembl
RefSeq Acc Id: NM_080401   ⟹   NP_536326
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81162,549,360 - 162,565,456 (+)NCBI
mRatBN7.21153,138,197 - 153,154,294 (+)NCBI
Rnor_6.01163,797,660 - 163,813,756 (+)NCBI
Rnor_5.01169,997,286 - 170,016,829 (+)NCBI
RGSC_v3.41156,125,969 - 156,142,065 (+)RGD
Celera1151,224,671 - 151,240,729 (+)RGD
Sequence:
RefSeq Acc Id: XM_006229718   ⟹   XP_006229780
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81162,545,660 - 162,564,758 (+)NCBI
mRatBN7.21153,134,503 - 153,153,554 (+)NCBI
Rnor_6.01163,794,136 - 163,813,751 (+)NCBI
Rnor_5.01169,997,286 - 170,016,829 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006229720   ⟹   XP_006229782
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81162,547,414 - 162,564,758 (+)NCBI
mRatBN7.21153,136,144 - 153,153,554 (+)NCBI
Rnor_6.01163,794,543 - 163,813,751 (+)NCBI
Rnor_5.01169,997,286 - 170,016,829 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008759667   ⟹   XP_008757889
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81162,556,967 - 162,564,758 (+)NCBI
mRatBN7.21153,138,460 - 153,153,554 (+)NCBI
Rnor_6.01163,797,923 - 163,813,561 (+)NCBI
Sequence:
RefSeq Acc Id: XM_063270171   ⟹   XP_063126241
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81162,546,552 - 162,564,758 (+)NCBI
RefSeq Acc Id: NP_536326   ⟸   NM_080401
- UniProtKB: G3V819 (UniProtKB/TrEMBL),   A6I6F2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006229780   ⟸   XM_006229718
- Peptide Label: isoform X1
- UniProtKB: G3V819 (UniProtKB/TrEMBL),   A6I6F2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006229782   ⟸   XM_006229720
- Peptide Label: isoform X1
- UniProtKB: G3V819 (UniProtKB/TrEMBL),   A6I6F2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008757889   ⟸   XM_008759667
- Peptide Label: isoform X2
- Sequence:
Ensembl Acc Id: ENSRNOP00000021674   ⟸   ENSRNOT00000021674

Name Modeler Protein Id AA Range Protein Structure
AF-G3V819-F1-model_v2 AlphaFold G3V819 1-354 view protein structure


eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen



1 to 20 of 20 rows
Database
Acc Id
Source(s)
BioCyc Gene G2FUF-58414 BioCyc
Ensembl Genes ENSRNOG00000015982 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000021674 ENTREZGENE
  ENSRNOT00000021674.6 UniProtKB/TrEMBL
Gene3D-CATH 3.30.2460.20 UniProtKB/TrEMBL
InterPro Wnt UniProtKB/TrEMBL
  Wnt_C UniProtKB/TrEMBL
  Wnt_grthfactor_CS UniProtKB/TrEMBL
KEGG Report rno:140584 UniProtKB/TrEMBL
NCBI Gene 140584 ENTREZGENE
PANTHER PTHR12027:SF7 UniProtKB/TrEMBL
  Wnt UniProtKB/TrEMBL
Pfam wnt UniProtKB/TrEMBL
PhenoGen Wnt11 PhenoGen
PRINTS WNTPROTEIN UniProtKB/TrEMBL
PROSITE WNT1 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000015982 RatGTEx
SMART WNT1 UniProtKB/TrEMBL
UniProt A6I6F2 ENTREZGENE, UniProtKB/TrEMBL
  G3V819 ENTREZGENE, UniProtKB/TrEMBL
1 to 20 of 20 rows


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2017-03-29 Wnt11  Wnt family member 11  Wnt11  wingless-type MMTV integration site family, member 11  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-11-14 Wnt11  wingless-type MMTV integration site family, member 11  Wnt11  wingless-related MMTV integration site 11  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-02-22 Wnt11  wingless-related MMTV integration site 11  Wnt11  wingless-type MMTV integration site family, member 11  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2002-08-07 Wnt11  wingless-type MMTV integration site family, member 11      Symbol and Name status set to provisional 70820 PROVISIONAL

Note Type Note Reference
gene_product member of the Wnt family of secreted glycoproteins 727217