Myo1d (myosin ID) - Rat Genome Database

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Gene: Myo1d (myosin ID) Rattus norvegicus
Analyze
Symbol: Myo1d
Name: myosin ID
RGD ID: 621321
Description: Enables several functions, including actin filament binding activity; calcium-dependent protein binding activity; and calmodulin binding activity. Involved in forebrain development. Located in several cellular components, including axolemma; basolateral plasma membrane; and brush border. Part of myosin complex. Orthologous to human MYO1D (myosin ID); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 5-methoxy-2-\{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl\}-1H-benzimidazole; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: MGC93573; Myo1c; myosin 1C; myosin heavy chain myr 4; myosin IC; myosin-Id; myosin1C; Myr2; Myr4; Unconventional myosin from rat 4 for myosin I heavy chain; unconventional myosin-Id
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Allele / Splice: Myo1dTn(sb-T2/Bart3)2.334Mcwi
Genetic Models: F344-Myo1dTn(sb-T2/Bart3)2.334Mcwi
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81065,986,900 - 66,263,538 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1065,975,122 - 66,263,958 (-)EnsemblGRCr8
mRatBN7.21065,489,153 - 65,765,812 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1065,489,154 - 65,766,349 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1070,117,073 - 70,393,698 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01069,622,393 - 69,899,014 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01065,084,076 - 65,360,306 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01067,866,939 - 68,142,864 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1067,866,940 - 68,142,864 (-)Ensemblrn6Rnor6.0
Rnor_5.01067,520,649 - 67,811,744 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41068,720,729 - 68,997,721 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1064,447,472 - 64,723,456 (-)NCBICelera
Cytogenetic Map10q26NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,2-dimethylhydrazine  (ISO)
1-chloro-2,4-dinitrobenzene  (ISO)
17beta-estradiol  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2-butoxyethanol  (ISO)
3,4-methylenedioxymethamphetamine  (ISO)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
3-methylcholanthrene  (ISO)
3-Nitrobenzanthrone  (ISO)
4,4'-sulfonyldiphenol  (ISO)
4-hydroxyphenyl retinamide  (ISO)
5-methoxy-2-\{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl\}-1H-benzimidazole  (EXP)
6-propyl-2-thiouracil  (EXP)
acrolein  (ISO)
aflatoxin B1  (ISO)
all-trans-retinoic acid  (ISO)
amiodarone  (EXP)
amitrole  (EXP)
ammonium chloride  (EXP)
aristolochic acid A  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
benzbromarone  (EXP)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
beta-lapachone  (ISO)
beta-naphthoflavone  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
Bisphenol B  (ISO)
bisphenol F  (ISO)
Butylbenzyl phthalate  (EXP)
calcitriol  (ISO)
CGP 52608  (ISO)
chlordecone  (ISO)
cisplatin  (ISO)
clofibrate  (EXP)
cobalt dichloride  (EXP,ISO)
Cuprizon  (EXP)
cycloheximide  (ISO)
dexamethasone  (ISO)
diethylstilbestrol  (ISO)
dioxygen  (ISO)
diuron  (EXP)
dorsomorphin  (ISO)
endosulfan  (EXP)
entinostat  (ISO)
ethanol  (ISO)
flavonoids  (EXP)
folic acid  (ISO)
formaldehyde  (ISO)
fulvestrant  (ISO)
genistein  (ISO)
gentamycin  (EXP)
glafenine  (EXP)
glycidol  (EXP)
indometacin  (ISO)
inulin  (ISO)
isoniazide  (ISO)
L-ethionine  (EXP)
mercury dibromide  (ISO)
methyl methanesulfonate  (ISO)
N-methyl-4-phenylpyridinium  (ISO)
N-nitrosomorpholine  (EXP)
nefazodone  (EXP)
nimesulide  (EXP)
omeprazole  (EXP)
oxaliplatin  (EXP)
ozone  (ISO)
panobinostat  (ISO)
paracetamol  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
perfluorooctanoic acid  (ISO)
phenobarbital  (ISO)
phenylmercury acetate  (ISO)
pirinixic acid  (EXP,ISO)
profenofos  (EXP)
propiconazole  (EXP)
SB 431542  (ISO)
silicon dioxide  (ISO)
sodium arsenite  (ISO)
sulfadimethoxine  (EXP)
sulforaphane  (ISO)
testosterone  (ISO)
tetrachloromethane  (EXP,ISO)
thapsigargin  (EXP)
thioacetamide  (EXP)
titanium dioxide  (ISO)
topotecan  (EXP,ISO)
triadimefon  (EXP)
trichostatin A  (ISO)
triphenyl phosphate  (ISO)
triptonide  (ISO)
tunicamycin  (ISO)
urethane  (ISO)
valproic acid  (ISO)
vinclozolin  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Rat myr 4 defines a novel subclass of myosin I: identification, distribution, localization, and mapping of calmodulin-binding sites with differential calcium sensitivity. Bahler M, etal., J Cell Biol 1994 Jul;126(2):375-89.
2. Differential localization and dynamics of class I myosins in the enterocyte microvillus. Benesh AE, etal., Mol Biol Cell. 2010 Mar 15;21(6):970-8. doi: 10.1091/mbc.E09-07-0638. Epub 2010 Jan 20.
3. Myosin-I isozymes in neonatal rodent auditory and vestibular epithelia. Dumont RA, etal., J Assoc Res Otolaryngol 2002 Dec;3(4):375-89. Epub 2002 Feb 27.
4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
5. The two IQ-motifs and Ca2+/calmodulin regulate the rat myosin 1d ATPase activity. Kohler D, etal., FEBS J. 2005 May;272(9):2189-97.
6. Different degrees of lever arm rotation control myosin step size. Kohler D, etal., J Cell Biol. 2003 Apr 28;161(2):237-41.
7. Axonal isoforms of myosin-I. Lund LM, etal., Biochem Biophys Res Commun. 2005 May 13;330(3):857-64.
8. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
9. GOA pipeline RGD automated data pipeline
10. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
11. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
12. Comprehensive gene review and curation RGD comprehensive gene curation
13. Tentative Sequence Identification Numbers Tentative Sequence Data IDs. TIGR Gene Index, Rat Data
14. Two-dimensional electrophoresis with cationic detergents: a powerful tool for the proteomic analysis of myelin proteins. Part 2: analytical aspects. Yamaguchi Y, etal., J Neurosci Res. 2008 Mar;86(4):766-75.
Additional References at PubMed
PMID:11208135   PMID:12477932   PMID:15014434   PMID:15489334   PMID:17634366   PMID:19056867   PMID:19199708   PMID:19389623   PMID:20039646   PMID:21330445   PMID:22114352   PMID:22284616  
PMID:22871113   PMID:23376485   PMID:23533145   PMID:24625528   PMID:24903835   PMID:29476059  


Genomics

Comparative Map Data
Myo1d
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81065,986,900 - 66,263,538 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1065,975,122 - 66,263,958 (-)EnsemblGRCr8
mRatBN7.21065,489,153 - 65,765,812 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1065,489,154 - 65,766,349 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1070,117,073 - 70,393,698 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01069,622,393 - 69,899,014 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01065,084,076 - 65,360,306 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01067,866,939 - 68,142,864 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1067,866,940 - 68,142,864 (-)Ensemblrn6Rnor6.0
Rnor_5.01067,520,649 - 67,811,744 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41068,720,729 - 68,997,721 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1064,447,472 - 64,723,456 (-)NCBICelera
Cytogenetic Map10q26NCBI
MYO1D
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381732,492,522 - 32,877,124 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1732,492,522 - 32,877,192 (-)Ensemblhg38GRCh38
GRCh371730,819,540 - 31,204,142 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361727,843,741 - 28,228,015 (-)NCBIBuild 36Build 36hg18NCBI36
Build 341727,843,740 - 28,228,015NCBI
Celera1727,729,830 - 28,114,502 (-)NCBICelera
Cytogenetic Map17q11.2NCBI
HuRef1727,005,843 - 27,390,754 (-)NCBIHuRef
CHM1_11730,882,090 - 31,266,671 (-)NCBICHM1_1
T2T-CHM13v2.01733,438,289 - 33,823,203 (-)NCBIT2T-CHM13v2.0
Myo1d
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391180,372,945 - 80,670,881 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1180,372,952 - 80,670,851 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm381180,482,126 - 80,780,055 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1180,482,126 - 80,780,025 (-)Ensemblmm10GRCm38
MGSCv371180,295,629 - 80,593,527 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361180,400,022 - 80,596,220 (-)NCBIMGSCv36mm8
Celera1190,120,134 - 90,418,853 (-)NCBICelera
Cytogenetic Map11B5NCBI
cM Map1147.95NCBI
Myo1d
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554817,413,211 - 7,752,198 (-)Ensembl
ChiLan1.0NW_0049554817,413,211 - 7,752,198 (-)NCBIChiLan1.0ChiLan1.0
MYO1D
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21931,581,486 - 31,964,509 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11733,462,675 - 33,845,563 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01723,900,814 - 24,283,721 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11724,287,194 - 24,574,209 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1724,284,959 - 24,572,183 (+)EnsemblpanPan2panpan1.1
MYO1D
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1940,171,426 - 40,497,556 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl940,171,158 - 40,496,210 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha939,330,493 - 39,656,452 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0940,987,302 - 41,313,614 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl940,986,996 - 41,313,603 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1939,773,164 - 40,099,782 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0940,067,715 - 40,393,998 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0940,142,489 - 40,468,690 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Myo1d
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560239,224,247 - 39,531,010 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365382,102,186 - 2,408,954 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049365382,102,192 - 2,408,953 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MYO1D
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1242,120,368 - 42,489,194 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.11242,120,373 - 42,489,191 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21243,931,996 - 44,248,454 (+)NCBISscrofa10.2Sscrofa10.2susScr3
MYO1D
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11626,050,272 - 26,425,568 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1626,049,861 - 26,425,455 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_0236660753,614,758 - 3,993,139 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Myo1d
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624875543,260 - 877,953 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_004624875544,065 - 877,958 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Myo1d
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v1989,659,688 - 89,932,566 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Myo1d
1889 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:238
Count of miRNA genes:151
Interacting mature miRNAs:169
Transcripts:ENSRNOT00000004609
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1549846Scl47Serum cholesterol level QTL 473.6blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)105107189796071897Rat
152025229Scl83Serum cholesterol level QTL 834.33blood cholesterol amount (VT:0000180)103621155669161158Rat
1578779Tcas10Tongue tumor susceptibility QTL 103.12tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)103179628176796281Rat
152025227Bw195Body weight QTL 1955.73body mass (VT:0001259)104748901769161158Rat
1298069Bp168Blood pressure QTL 1685.5blood pressure trait (VT:0000183)systolic blood pressure (CMO:0000004)102702353598502431Rat
2293669Bmd33Bone mineral density QTL 334.50.0001femur strength trait (VT:0010010)femoral neck polar moment of inertia (CMO:0001670)102744378772443787Rat
152025224Bw193Body weight QTL 1936.47body mass (VT:0001259)105216243375582749Rat
61449Ciaa2CIA Autoantibody QTL 27.1blood autoantibody amount (VT:0003725)calculated serum anti-type 2 collagen antibody titer (CMO:0001279)1063719161107713808Rat
631552Vetf2Vascular elastic tissue fragility QTL 24.50.0002aorta elastic tissue integrity trait (VT:0010556)artery internal elastic lamina non-tumorous lesion count (CMO:0001913)103550938391417879Rat
631557Bp136Blood pressure QTL 1360.003arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)105686844076129113Rat
61325Aia5Adjuvant induced arthritis QTL 50.01joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1023948641107713808Rat
1298078Stresp5Stress response QTL 52.990.00025blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)1042546145107713808Rat
2293679Bmd30Bone mineral density QTL 303.50.0001femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)102744378772443787Rat
1549831Bss6Bone structure and strength QTL 64lumbar vertebra strength trait (VT:0010574)vertebra ultimate force (CMO:0001678)1058073360103073360Rat
70164Bw21Body weight QTL 214.360.00005body mass (VT:0001259)body weight (CMO:0000012)105429633699451733Rat
2298548Neuinf7Neuroinflammation QTL 73.4nervous system integrity trait (VT:0010566)spinal cord RT1-B protein level (CMO:0002132)1064939013107713808Rat
61463Bp12Blood pressure QTL 126.30.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)104183127886831278Rat
1579919Bp281Blood pressure QTL 2810.01arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)105046480295464802Rat
2300218Hpcl2Hepatic cholesterol level QTL 2liver cholesterol amount (VT:0010498)liver cholesterol level (CMO:0001597)104552916496099749Rat
8694173Bw149Body weight QTL 1494.380.001body mass (VT:0001259)body weight gain (CMO:0000420)104493935989939359Rat
70171Cari1Carrageenan-induced inflammation QTL 14.90.0005hypodermis integrity trait (VT:0010550)inflammatory exudate volume (CMO:0001429)1054296227107713808Rat
10450493Bp382Blood pressure QTL 3820.002arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)105086028895860288Rat
724527Bp148Blood pressure QTL 1480.0001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)102895035373950353Rat
2300171Bmd58Bone mineral density QTL 584.90.0001lumbar vertebra mineral mass (VT:0010511)volumetric bone mineral density (CMO:0001553)102744378772443787Rat
61354Pia10Pristane induced arthritis QTL 100.01joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1023948641107713808Rat
2301967Cm73Cardiac mass QTL 734.55heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)101499153586964295Rat
2313103Bss80Bone structure and strength QTL 8020.0001tibia strength trait (VT:1000284)tibia midshaft endosteal cross-sectional area (CMO:0001716)1062556066107556066Rat
70188BpQTLcluster1Blood pressure QTL cluster 14.864arterial blood pressure trait (VT:2000000)pulse pressure (CMO:0000292)14282327487823274Rat
2313105Bss79Bone structure and strength QTL 791.80.0001tibia size trait (VT:0100001)tibia midshaft cross-sectional area (CMO:0001717)1062556066107556066Rat
9589030Epfw9Epididymal fat weight QTL 919.240.001epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)104493935989939359Rat
2293652Bmd22Bone mineral density QTL 224.90.0001femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)102744378772443787Rat
2316949Gluco60Glucose level QTL 603.7blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)1014991535107556066Rat
70198BpQTLcluster9Blood pressure QTL cluster 92.94arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)104282327487823274Rat
2306970Anxrr22Anxiety related response QTL 225.95fear/anxiety-related behavior trait (VT:1000241)number of periods of voluntary immobility (CMO:0001045)106184349698710773Rat
2306787Ean3Experimental allergic neuritis QTL 33.1nervous system integrity trait (VT:0010566)body weight loss (CMO:0001399)105429622767476781Rat
7387312Bw125Body weight QTL 12530.0047retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight (CMO:0000356)1065390777107713808Rat
724556Pur2Proteinuria QTL 25.5urine protein amount (VT:0005160)urine protein level (CMO:0000591)102293137391127454Rat
8662860Vetf10Vascular elastic tissue fragility QTL 10artery integrity trait (VT:0010639)number of ruptures of the internal elastic lamina of the abdominal aorta and iliac arteries (CMO:0002562)10666092373950353Rat
2306792Ean4Experimental allergic neuritis QTL 44nervous system integrity trait (VT:0010566)IFNG-secreting splenocyte count (CMO:0002122)104949549294495492Rat
61387Bp1Blood pressure QTL 15.1arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)1052269185107713808Rat
1354587Kidm21Kidney mass QTL 213.3kidney mass (VT:0002707)right kidney wet weight (CMO:0000082)101553301273695498Rat
634329Pia15Pristane induced arthritis QTL 153.1joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)102466212373695339Rat
2298481Eau9Experimental allergic uveoretinitis QTL 90.0169uvea integrity trait (VT:0010551)experimental autoimmune uveitis score (CMO:0001504)106413959783061459Rat
2298480Eau7Experimental allergic uveoretinitis QTL 70.0049uvea integrity trait (VT:0010551)experimental autoimmune uveitis score (CMO:0001504)103550938380509383Rat
1358915Stresp7Stress response QTL 73.52blood norepinephrine amount (VT:0005663)plasma norepinephrine level (CMO:0001010)1065307813107713808Rat
70363Bp71Blood pressure QTL 710.04arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1061843496106843496Rat
61402Niddm3Non-insulin dependent diabetes mellitus QTL 34.58blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)106184363383061236Rat
1331791Cm31Cardiac mass QTL 313.84606heart mass (VT:0007028)heart wet weight (CMO:0000069)102980091091417879Rat
2289985Bp305Blood pressure QTL 305arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)102907697874076978Rat
631530Tls3T-lymphoma susceptibility QTL 300.0001thymus integrity trait (VT:0010555)percentage of study population developing T-cell lymphomas during a period of time (CMO:0001911)102758722696099902Rat
1354608Cm33Cardiac mass QTL 332.8heart left ventricle mass (VT:0007031)heart left ventricle wet weight (CMO:0000071)105530797293608131Rat
1558643Cm44Cardiac mass QTL 444.80.0000368heart mass (VT:0007028)heart wet weight (CMO:0000069)1061843496100198886Rat
8552805Bw145Body weight QTL 1452.2body mass (VT:0001259)change in body weight to body weight ratio (CMO:0002216)104360879388608793Rat
631267Cia20Collagen induced arthritis QTL 203.2joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1023948641107713808Rat
1331839Eae18bExperimental allergic encephalomyelitis QTL 18b5.80.03nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis severity score (CMO:0001419)106174653268282731Rat
2293705Bmd25Bone mineral density QTL 257.10.0001femur mineral mass (VT:0010011)compact volumetric bone mineral density (CMO:0001730)102744378772443787Rat
631269Cia22Collagen induced arthritis QTL 228.9joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1040535708107713808Rat
1576308Schws1Schwannoma susceptibility QTL 10.0041nervous system integrity trait (VT:0010566)percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)1040535708107713808Rat
631268Cia21Collagen induced arthritis QTL 213.1joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1014991535107713808Rat
7207811Bmd90Bone mineral density QTL 905.2femur size trait (VT:1000369)femoral neck cross-sectional area (CMO:0001697)104994371094943710Rat
631270Cia23Collagen induced arthritis QTL 233.9joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1040535708107713808Rat
631526Bp76Blood pressure QTL 760.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)106184363367241334Rat
1581559Eae18Experimental allergic encephalomyelitis QTL 180.00002nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis severity score (CMO:0001419)1066108888107555881Rat
1576311Pia26Pristane induced arthritis QTL 26joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)103112911376129113Rat
7411614Foco18Food consumption QTL 180.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)104493935989939359Rat
6893336Cm75Cardiac mass QTL 750.10.87heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)1061843496100198886Rat
631547Bp87Blood pressure QTL 874.5arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)104786912992869129Rat
61427Cia16Collagen induced arthritis QTL 163.2joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)10686461896620484Rat
2292436Bp310Blood pressure QTL 310arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)105060467795604677Rat
12880050Am10Aortic mass QTL 100.016aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)103950348784503487Rat
6893342Cm78Cardiac mass QTL 780.10.88heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)103550938388177745Rat
634354Rends3Renal damage susceptibility QTL 30.05kidney blood vessel morphology trait (VT:0000530)organ lesion measurement (CMO:0000677)1061997479106997479Rat
631542Bp82Blood pressure QTL 826.8arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)102702353599451848Rat

Markers in Region
D10Rat29  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr81066,108,698 - 66,108,888 (+)Marker Load Pipeline
Rnor_6.01067,988,035 - 67,988,218NCBIRnor6.0
Rnor_5.01067,642,121 - 67,642,304UniSTSRnor5.0
RGSC_v3.41068,842,878 - 68,843,272RGDRGSC3.4
RGSC_v3.41068,842,891 - 68,843,074UniSTSRGSC3.4
Celera1064,569,293 - 64,569,476UniSTS
RGSC_v3.11068,856,501 - 68,856,895RGD
RH 2.0 Map10657.7RGD
SHRSP x BN Map1046.5699RGD
FHH x ACI Map1053.73RGD
Cytogenetic Map10q26UniSTS
D10Chm124  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.01068,135,192 - 68,135,379NCBIRnor6.0
Rnor_5.01067,804,072 - 67,804,259UniSTSRnor5.0
RGSC_v3.41068,990,048 - 68,990,235UniSTSRGSC3.4
Cytogenetic Map10q26UniSTS
RH128556  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21065,489,302 - 65,489,519 (+)MAPPERmRatBN7.2
Rnor_6.01067,867,089 - 67,867,305NCBIRnor6.0
Rnor_5.01067,520,799 - 67,521,015UniSTSRnor5.0
RGSC_v3.41068,720,879 - 68,721,095UniSTSRGSC3.4
Celera1064,447,622 - 64,447,838UniSTS
Cytogenetic Map10q26UniSTS
BF386417  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr81066,000,671 - 66,000,828 (+)Marker Load Pipeline
mRatBN7.21065,502,924 - 65,503,081 (+)MAPPERmRatBN7.2
Rnor_6.01067,880,711 - 67,880,867NCBIRnor6.0
Rnor_5.01067,534,564 - 67,534,720UniSTSRnor5.0
RGSC_v3.41068,734,823 - 68,734,979UniSTSRGSC3.4
Celera1064,461,236 - 64,461,392UniSTS
Cytogenetic Map10q26UniSTS
BI292081  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21065,740,839 - 65,741,036 (+)MAPPERmRatBN7.2
Rnor_6.01068,117,901 - 68,118,097NCBIRnor6.0
Rnor_5.01067,786,781 - 67,786,977UniSTSRnor5.0
RGSC_v3.41068,972,757 - 68,972,953UniSTSRGSC3.4
Celera1064,698,561 - 64,698,757UniSTS
Cytogenetic Map10q26UniSTS
BI274510  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21065,723,927 - 65,724,022 (+)MAPPERmRatBN7.2
Rnor_6.01068,100,990 - 68,101,084NCBIRnor6.0
Rnor_5.01067,769,870 - 67,769,964UniSTSRnor5.0
RGSC_v3.41068,955,846 - 68,955,940UniSTSRGSC3.4
Celera1064,681,651 - 64,681,745UniSTS
Cytogenetic Map10q26UniSTS


Genetic Models
This gene Myo1d is modified in the following models/strains:
F344-Myo1dTn(sb-T2/Bart3)2.334Mcwi    


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
23 14 82 189 91 90 59 120 59 6 475 247 24 166 138 127 31 29 29

Sequence


Ensembl Acc Id: ENSRNOT00000004609   ⟹   ENSRNOP00000004609
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1065,986,901 - 66,263,538 (-)Ensembl
mRatBN7.2 Ensembl1065,489,154 - 65,765,812 (-)Ensembl
Rnor_6.0 Ensembl1067,866,940 - 68,142,864 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000108255   ⟹   ENSRNOP00000091463
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1065,986,901 - 66,263,958 (-)Ensembl
mRatBN7.2 Ensembl1065,489,154 - 65,766,349 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000125487   ⟹   ENSRNOP00000107785
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1065,986,901 - 66,263,538 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000162168   ⟹   ENSRNOP00000112609
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1065,975,122 - 66,263,585 (-)Ensembl
RefSeq Acc Id: NM_012983   ⟹   NP_037115
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81065,986,900 - 66,263,538 (-)NCBI
mRatBN7.21065,489,153 - 65,765,812 (-)NCBI
Rnor_6.01067,866,939 - 68,142,864 (-)NCBI
Rnor_5.01067,520,649 - 67,811,744 (-)NCBI
RGSC_v3.41068,720,729 - 68,997,721 (-)RGD
Celera1064,447,472 - 64,723,456 (-)RGD
Sequence:
RefSeq Acc Id: XM_063268468   ⟹   XP_063124538
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81065,986,900 - 66,211,912 (-)NCBI
RefSeq Acc Id: XM_063268469   ⟹   XP_063124539
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81065,986,900 - 66,250,282 (-)NCBI
RefSeq Acc Id: NP_037115   ⟸   NM_012983
- UniProtKB: Q5PQU2 (UniProtKB/Swiss-Prot),   Q63357 (UniProtKB/Swiss-Prot),   A6HHC1 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000004609   ⟸   ENSRNOT00000004609
Ensembl Acc Id: ENSRNOP00000091463   ⟸   ENSRNOT00000108255
RefSeq Acc Id: XP_063124539   ⟸   XM_063268469
- Peptide Label: isoform X1
- UniProtKB: A0A8I6GJN3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063124538   ⟸   XM_063268468
- Peptide Label: isoform X1
- UniProtKB: A0A8I6GJN3 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000107785   ⟸   ENSRNOT00000125487
Ensembl Acc Id: ENSRNOP00000112609   ⟸   ENSRNOT00000162168
Protein Domains
IQ   Myosin motor   TH1

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q63357-F1-model_v2 AlphaFold Q63357 1-1006 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13697504
Promoter ID:EPDNEW_R8029
Type:initiation region
Name:Myo1d_1
Description:myosin ID
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01068,142,930 - 68,142,990EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:621321 AgrOrtholog
BioCyc Gene G2FUF-23964 BioCyc
Ensembl Genes ENSRNOG00000003276 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000004609 ENTREZGENE
  ENSRNOT00000004609.5 UniProtKB/Swiss-Prot
  ENSRNOT00000108255 ENTREZGENE
Gene3D-CATH 1.10.10.820 UniProtKB/Swiss-Prot
  1.20.5.4820 UniProtKB/Swiss-Prot
  1.20.58.530 UniProtKB/Swiss-Prot
  3.40.850.10 UniProtKB/Swiss-Prot
  Myosin VI head, motor domain, U50 subdomain UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:7106587 IMAGE-MGC_LOAD
InterPro IQ_motif_EF-hand-BS UniProtKB/Swiss-Prot
  Kinesin_motor_dom_sf UniProtKB/Swiss-Prot
  Myosin_head_motor_dom UniProtKB/Swiss-Prot
  Myosin_TH1 UniProtKB/Swiss-Prot
  MYSc_Myo1 UniProtKB/Swiss-Prot
  P-loop_NTPase UniProtKB/Swiss-Prot
KEGG Report rno:25485 UniProtKB/Swiss-Prot
MGC_CLONE MGC:93573 IMAGE-MGC_LOAD
NCBI Gene 25485 ENTREZGENE
PANTHER MYOSIN UniProtKB/Swiss-Prot
  UNCONVENTIONAL MYOSIN-ID UniProtKB/Swiss-Prot
Pfam Myosin_head UniProtKB/Swiss-Prot
  Myosin_TH1 UniProtKB/Swiss-Prot
  PF00612 UniProtKB/Swiss-Prot
PhenoGen Myo1d PhenoGen
PRINTS MYOSINHEAVY UniProtKB/Swiss-Prot
PROSITE MYOSIN_MOTOR UniProtKB/Swiss-Prot
  PS50096 UniProtKB/Swiss-Prot
  TH1 UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000003276 RatGTEx
SMART MYSc UniProtKB/Swiss-Prot
  SM00015 UniProtKB/Swiss-Prot
Superfamily-SCOP SSF52540 UniProtKB/Swiss-Prot
TIGR TC214852
UniProt A0A8I6GJN3 ENTREZGENE, UniProtKB/TrEMBL
  A0ABK0LB45_RAT UniProtKB/TrEMBL
  A0ABK0M8M9_RAT UniProtKB/TrEMBL
  A6HHC1 ENTREZGENE, UniProtKB/TrEMBL
  A6HHC2_RAT UniProtKB/TrEMBL
  A6HHC3_RAT UniProtKB/TrEMBL
  MYO1D_RAT UniProtKB/Swiss-Prot
  Q5PQU2 ENTREZGENE
  Q63357 ENTREZGENE
UniProt Secondary Q5PQU2 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2005-12-02 Myo1d  myosin ID  Myo1c  myosin IC  Symbol and Name updated to reflect Human and Mouse nomenclature 1298993 APPROVED
2003-04-09 Myo1c  myosin1C    myosin 1C  Symbol and Name updated 629477 APPROVED
2003-03-06 Myo1c  myosin1C  Myo1d  myosin ID  Data merged from RGD:3145 628472 PROVISIONAL
2002-11-06 Myo1d  myosin ID  Myr4  Unconventional myosin from rat 4 for myosin I heavy chain  Symbol and Name updated 625702 APPROVED
2002-08-07 Myo1c        Symbol and Name status set to provisional 70820 PROVISIONAL
2002-06-10 Myr4  Unconventional myosin from rat 4 for myosin I heavy chain      Symbol and Name status set to approved 70586 APPROVED

RGD Curation Notes
Note Type Note Reference
gene_cellular_localization localized to the cell bodies and apical dendrites of neurons 633383