Ralbp1 (ralA binding protein 1) - Rat Genome Database

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Gene: Ralbp1 (ralA binding protein 1) Rattus norvegicus
Analyze
Symbol: Ralbp1
Name: ralA binding protein 1
RGD ID: 621134
Description: Enables GTPase activator activity and small GTPase binding activity. Involved in several processes, including negative regulation of smooth muscle cell proliferation; regulation of intracellular signal transduction; and small GTPase-mediated signal transduction. Is active in Schaffer collateral - CA1 synapse. Human ortholog(s) of this gene implicated in pancreatic adenocarcinoma. Orthologous to human RALBP1 (ralA binding protein 1); PARTICIPATES IN doxorubicin pharmacokinetics pathway; vinblastine pharmacodynamics pathway; vincristine pharmacodynamics pathway; INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: cytocentrin; dinitrophenyl S-glutathione ATPase; DNP-SG ATPase; MGC108645; ral-interacting protein 1; ralA-binding protein 1; RIP1; RLIP76
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Related Pseudogenes: Ralbp1-ps1  
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr89112,903,289 - 112,940,093 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl9112,903,302 - 112,939,659 (-)EnsemblGRCr8
mRatBN7.29105,456,425 - 105,493,235 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl9105,456,425 - 105,492,707 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx9113,864,919 - 113,901,662 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.09118,974,826 - 119,011,623 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.09117,330,768 - 117,367,512 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.09113,579,107 - 113,598,477 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl9113,579,107 - 113,598,480 (-)Ensemblrn6Rnor6.0
Rnor_5.09113,111,327 - 113,130,697 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.49104,617,400 - 104,653,856 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera9102,832,909 - 102,869,009 (-)NCBICelera
RGSC_v3.19104,826,889 - 104,863,322 (-)NCBI
Cytogenetic Map9q37NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(S)-colchicine  (ISO)
1,2-dimethylhydrazine  (ISO)
17alpha-ethynylestradiol  (EXP)
17beta-hydroxy-5alpha-androstan-3-one  (ISO)
2,2',4,4',5,5'-hexachlorobiphenyl  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4-dinitrotoluene  (EXP)
2,6-dinitrotoluene  (EXP)
3,3',5,5'-tetrabromobisphenol A  (EXP)
3,4-dichloroaniline  (ISO)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
3H-1,2-dithiole-3-thione  (EXP)
4,4'-sulfonyldiphenol  (ISO)
4-hydroxynon-2-enal  (ISO)
6-propyl-2-thiouracil  (EXP)
aflatoxin B1  (ISO)
amitrole  (EXP)
arsenous acid  (ISO)
ATP  (ISO)
atrazine  (ISO)
benzo[a]pyrene  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
Brodifacoum  (EXP)
caffeine  (ISO)
carbon nanotube  (ISO)
CGP 52608  (ISO)
chlorpyrifos  (ISO)
cisplatin  (ISO)
clotrimazole  (EXP)
copper(II) sulfate  (ISO)
coumarin  (ISO)
dexamethasone  (ISO)
diarsenic trioxide  (ISO)
dibutyl phthalate  (EXP)
doxorubicin  (ISO)
elemental selenium  (ISO)
ethanol  (ISO)
finasteride  (EXP)
flutamide  (EXP)
folic acid  (ISO)
FR900359  (ISO)
fulvestrant  (ISO)
gentamycin  (EXP)
hexadecanoic acid  (ISO)
indometacin  (ISO)
inulin  (ISO)
leukotriene C4  (ISO)
methapyrilene  (EXP)
methimazole  (EXP)
Monobutylphthalate  (EXP)
ochratoxin A  (EXP)
perfluorohexanesulfonic acid  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
phenobarbital  (ISO)
quercetin  (ISO)
selenium atom  (ISO)
silicon dioxide  (ISO)
sodium arsenite  (ISO)
sulfadimethoxine  (EXP)
sunitinib  (ISO)
titanium dioxide  (ISO)
triphenyl phosphate  (ISO)
triptonide  (ISO)
tungsten  (ISO)
urethane  (ISO)
valproic acid  (ISO)
vitamin E  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytosol  (IEA)
membrane  (IBA,ISO)
mitochondrion  (IEA,ISO,ISS)
nuclear body  (ISO)
nucleoplasm  (ISO)
nucleus  (IEA)
plasma membrane  (IEA,ISO)
Schaffer collateral - CA1 synapse  (EXP,IDA,IMP)
spindle pole  (IEA)

References

References - curated
# Reference Title Reference Citation
1. The brain exocyst complex interacts with RalA in a GTP-dependent manner: identification of a novel mammalian Sec3 gene and a second Sec15 gene. Brymora A, etal., J Biol Chem. 2001 Aug 10;276(32):29792-7. Epub 2001 Jun 13.
2. Identification and characterization of Ral-binding protein 1, a potential downstream target of Ral GTPases. Cantor SB, etal., Mol Cell Biol 1995 Aug;15(8):4578-84.
3. Nitration of the mitochondrial complex I subunit NDUFB8 elicits RIP1- and RIP3-mediated necrosis. Davis CW, etal., Free Radic Biol Med. 2010 Jan 15;48(2):306-17. doi: 10.1016/j.freeradbiomed.2009.11.001. Epub 2009 Nov 5.
4. Pharmacological targeting of the mitochondrial phosphatase PTPMT1. Doughty-Shenton D, etal., J Pharmacol Exp Ther. 2010 May;333(2):584-92. doi: 10.1124/jpet.109.163329. Epub 2010 Feb 18.
5. Cyclin D1 interacts and collaborates with Ral GTPases enhancing cell detachment and motility. Fernandez RM, etal., Oncogene. 2011 Apr 21;30(16):1936-46. doi: 10.1038/onc.2010.577. Epub 2011 Jan 17.
6. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
7. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
8. Regulated RalBP1 binding to RalA and PSD-95 controls AMPA receptor endocytosis and LTD. Han K, etal., PLoS Biol. 2009 Sep;7(9):e1000187. Epub 2009 Sep 8.
9. Identification and characterization of a novel protein interacting with Ral-binding protein 1, a putative effector protein of Ral. Ikeda M, etal., J Biol Chem. 1998 Jan 9;273(2):814-21.
10. RLIP76 regulates PI3K/Akt signaling and chemo-radiotherapy resistance in pancreatic cancer. Leake K, etal., PLoS One. 2012;7(4):e34582. doi: 10.1371/journal.pone.0034582. Epub 2012 Apr 3.
11. Gender disparity in susceptibility to oxidative stress and apoptosis induced by autoantibodies specific to RLIP76 in vascular cells. Matarrese P, etal., Antioxid Redox Signal. 2011 Dec 1;15(11):2825-36. doi: 10.1089/ars.2011.3942. Epub 2011 Aug 8.
12. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
13. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
14. Eleostearic acid induces RIP1-mediated atypical apoptosis in a kinase-independent manner via ERK phosphorylation, ROS generation and mitochondrial dysfunction. Obitsu S, etal., Cell Death Dis. 2013 Jun 20;4:e674. doi: 10.1038/cddis.2013.188.
15. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
16. SMPDB Annotation Import Pipeline Pipeline to import SMPDB annotations from SMPDB into RGD
17. Cytocentrin is a Ral-binding protein involved in the assembly and function of the mitotic apparatus. Quaroni A and Paul EC, J Cell Sci. 1999 Mar;112 ( Pt 5):707-18.
18. Mitogenic responses of vascular smooth muscle cells to lipid peroxidation-derived aldehyde 4-hydroxy-trans-2-nonenal (HNE): role of aldose reductase-catalyzed reduction of the HNE-glutathione conjugates in regulating cell growth. Ramana KV, etal., J Biol Chem. 2006 Jun 30;281(26):17652-60. Epub 2006 Apr 28.
19. GOA pipeline RGD automated data pipeline
20. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
21. Comprehensive gene review and curation RGD comprehensive gene curation
22. Expression of ral GTPases, their effectors, and activators in human bladder cancer. Smith SC, etal., Clin Cancer Res. 2007 Jul 1;13(13):3803-13.
23. Doxorubicin pathways: pharmacodynamics and adverse effects. Thorn CF, etal., Pharmacogenet Genomics. 2011 Jul;21(7):440-6. doi: 10.1097/FPC.0b013e32833ffb56.
Additional References at PubMed
PMID:7673236   PMID:8570186   PMID:9753634   PMID:10924126   PMID:11437348   PMID:12477932   PMID:15592429   PMID:24056301   PMID:28252651   PMID:28395284   PMID:28579326   PMID:33629276  
PMID:33828080   PMID:36223414  


Genomics

Comparative Map Data
Ralbp1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr89112,903,289 - 112,940,093 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl9112,903,302 - 112,939,659 (-)EnsemblGRCr8
mRatBN7.29105,456,425 - 105,493,235 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl9105,456,425 - 105,492,707 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx9113,864,919 - 113,901,662 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.09118,974,826 - 119,011,623 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.09117,330,768 - 117,367,512 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.09113,579,107 - 113,598,477 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl9113,579,107 - 113,598,480 (-)Ensemblrn6Rnor6.0
Rnor_5.09113,111,327 - 113,130,697 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.49104,617,400 - 104,653,856 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera9102,832,909 - 102,869,009 (-)NCBICelera
RGSC_v3.19104,826,889 - 104,863,322 (-)NCBI
Cytogenetic Map9q37NCBI
RALBP1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38189,475,009 - 9,538,114 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl189,474,991 - 9,538,114 (+)Ensemblhg38GRCh38
GRCh37189,475,511 - 9,538,112 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36189,465,530 - 9,528,106 (+)NCBIBuild 36Build 36hg18NCBI36
Build 34189,465,529 - 9,528,105NCBI
Celera189,359,767 - 9,422,335 (+)NCBICelera
Cytogenetic Map18p11.22NCBI
HuRef189,437,998 - 9,500,600 (+)NCBIHuRef
CHM1_1189,475,240 - 9,537,838 (+)NCBICHM1_1
T2T-CHM13v2.0189,636,797 - 9,701,515 (+)NCBIT2T-CHM13v2.0
Ralbp1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391766,155,410 - 66,192,750 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1766,155,413 - 66,192,793 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm381765,848,415 - 65,885,755 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1765,848,418 - 65,885,798 (-)Ensemblmm10GRCm38
MGSCv371766,197,755 - 66,217,171 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361765,747,984 - 65,784,368 (-)NCBIMGSCv36mm8
Celera1770,152,450 - 70,171,874 (-)NCBICelera
Cytogenetic Map17E1.1NCBI
cM Map1735.26NCBI
Ralbp1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554022,569,637 - 2,616,040 (-)Ensembl
ChiLan1.0NW_0049554022,571,672 - 2,616,040 (-)NCBIChiLan1.0ChiLan1.0
RALBP1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21728,912,572 - 28,978,250 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11814,604,717 - 14,670,844 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0184,747,555 - 4,810,710 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1187,028,188 - 7,091,369 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl187,028,188 - 7,090,934 (-)EnsemblpanPan2panpan1.1
RALBP1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1775,461,220 - 75,511,860 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl775,461,222 - 75,510,229 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha774,854,142 - 74,908,610 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0775,516,008 - 75,571,183 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl775,516,476 - 75,571,183 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1775,213,986 - 75,269,336 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0775,231,509 - 75,286,643 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0775,541,877 - 75,596,810 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Ralbp1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244049442,604,387 - 2,623,145 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366261,832,584 - 1,851,467 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049366261,832,703 - 1,851,486 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
RALBP1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl698,550,933 - 98,598,206 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1698,550,925 - 98,598,945 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2691,859,552 - 91,908,358 (-)NCBISscrofa10.2Sscrofa10.2susScr3
RALBP1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11868,353,823 - 68,415,221 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1868,391,245 - 68,413,555 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366605043,305,367 - 43,366,990 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ralbp1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462477018,127,025 - 18,147,465 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462477018,117,106 - 18,147,472 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Ralbp1
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v14175,839,086 - 175,858,348 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Ralbp1
223 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:149
Count of miRNA genes:128
Interacting mature miRNAs:134
Transcripts:ENSRNOT00000035606
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2290450Scl57Serum cholesterol level QTL 574.15blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)944458256121768150Rat
1300134Bp185Blood pressure QTL 1853.73arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)968875497121768150Rat
1354626Bvd1Brain ventricular dilatation QTL 13.730.001brain ventricle morphology trait (VT:0000822)hydrocephalus severity score (CMO:0001881)983161999118999486Rat
7794784Mcs31Mammary carcinoma susceptibility QTL 312.98mammary gland integrity trait (VT:0010552)mammary tumor incidence/prevalence measurement (CMO:0000946)985262459118999486Rat
2303178Bp334Blood pressure QTL 3343.70.01arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)986720043121768150Rat

Markers in Region
BF416967  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.29105,456,242 - 105,456,355 (+)MAPPERmRatBN7.2
Rnor_6.09113,578,925 - 113,579,037NCBIRnor6.0
Rnor_5.09113,111,145 - 113,111,257UniSTSRnor5.0
RGSC_v3.49104,617,218 - 104,617,330UniSTSRGSC3.4
Celera9102,832,727 - 102,832,839UniSTS
Cytogenetic Map9q37UniSTS
RH80877  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.29105,472,175 - 105,472,401 (+)MAPPERmRatBN7.2
Rnor_6.09113,594,858 - 113,595,083NCBIRnor6.0
Rnor_5.09113,127,078 - 113,127,303UniSTSRnor5.0
RGSC_v3.49104,633,151 - 104,633,376UniSTSRGSC3.4
Celera9102,848,683 - 102,848,908UniSTS
Cytogenetic Map9q37UniSTS
RH125071  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_5.09113,111,425 - 113,111,538NCBIRnor5.0
Rnor_5.02176,419,835 - 176,419,948NCBIRnor5.0
Rnor_5.016518,615 - 518,728NCBIRnor5.0
RGSC_v3.47722,104 - 722,216UniSTSRGSC3.4
RGSC_v3.49104,617,499 - 104,617,611UniSTSRGSC3.4
Celera9102,833,008 - 102,833,120UniSTS
Cytogenetic Map9q37UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 164 91 90 59 92 59 6 356 192 11 143 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000035606   ⟹   ENSRNOP00000033120
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl9105,456,425 - 105,492,628 (-)Ensembl
Rnor_6.0 Ensembl9113,579,107 - 113,598,477 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000084884   ⟹   ENSRNOP00000073726
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl9112,903,302 - 112,939,659 (-)Ensembl
mRatBN7.2 Ensembl9105,456,425 - 105,492,707 (-)Ensembl
Rnor_6.0 Ensembl9113,579,118 - 113,598,480 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000099492   ⟹   ENSRNOP00000090470
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl9112,903,302 - 112,939,659 (-)Ensembl
mRatBN7.2 Ensembl9105,456,425 - 105,492,707 (-)Ensembl
RefSeq Acc Id: NM_001393664   ⟹   NP_001380593
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr89112,903,289 - 112,940,093 (-)NCBI
mRatBN7.29105,456,425 - 105,493,235 (-)NCBI
RefSeq Acc Id: NM_032067   ⟹   NP_114456
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr89112,903,289 - 112,939,659 (-)NCBI
mRatBN7.29105,456,425 - 105,492,801 (-)NCBI
Rnor_6.09113,579,107 - 113,598,477 (-)NCBI
Rnor_5.09113,111,327 - 113,130,697 (-)NCBI
RGSC_v3.49104,617,400 - 104,653,856 (-)RGD
Celera9102,832,909 - 102,869,009 (-)RGD
Sequence:
RefSeq Acc Id: NP_114456   ⟸   NM_032067
- UniProtKB: Q62796 (UniProtKB/Swiss-Prot),   O55195 (UniProtKB/Swiss-Prot),   A0A0G2K694 (UniProtKB/TrEMBL),   Q5FVT1 (UniProtKB/TrEMBL),   A0A9K3Y7X7 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000033120   ⟸   ENSRNOT00000035606
Ensembl Acc Id: ENSRNOP00000073726   ⟸   ENSRNOT00000084884
Ensembl Acc Id: ENSRNOP00000090470   ⟸   ENSRNOT00000099492
RefSeq Acc Id: NP_001380593   ⟸   NM_001393664
- UniProtKB: Q62796 (UniProtKB/Swiss-Prot),   O55195 (UniProtKB/Swiss-Prot),   A0A0G2K694 (UniProtKB/TrEMBL),   Q5FVT1 (UniProtKB/TrEMBL),   A0A9K3Y7X7 (UniProtKB/TrEMBL)
Protein Domains
Rho-GAP

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q62796-F1-model_v2 AlphaFold Q62796 1-647 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:621134 AgrOrtholog
BioCyc Gene G2FUF-26478 BioCyc
Ensembl Genes ENSRNOG00000013461 Ensembl, ENTREZGENE
Ensembl Transcript ENSRNOT00000084884 ENTREZGENE
Gene3D-CATH 1.10.555.10 UniProtKB/Swiss-Prot
  1.20.58.90 UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:7374343 IMAGE-MGC_LOAD
InterPro RALBP1 UniProtKB/Swiss-Prot
  RalBP1-like_Ral-bd UniProtKB/Swiss-Prot
  Rho_GTPase_activation_prot UniProtKB/Swiss-Prot
  RhoGAP_dom UniProtKB/Swiss-Prot
KEGG Report rno:84014 UniProtKB/Swiss-Prot
MGC_CLONE MGC:108645 IMAGE-MGC_LOAD
NCBI Gene 84014 ENTREZGENE
PANTHER PTHR12783 UniProtKB/Swiss-Prot
  RALA-BINDING PROTEIN 1 UniProtKB/Swiss-Prot
Pfam RhoGAP UniProtKB/Swiss-Prot
  RLIP76_Ral-bd UniProtKB/Swiss-Prot
PharmGKB RALBP1 RGD
PhenoGen Ralbp1 PhenoGen
PROSITE RHOGAP UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000013461 RatGTEx
SMART RhoGAP UniProtKB/Swiss-Prot
Superfamily-SCOP SSF48350 UniProtKB/Swiss-Prot
UniProt A0A0G2K694 ENTREZGENE
  A0A8I6GI79_RAT UniProtKB/TrEMBL
  A0A9K3Y7X7 ENTREZGENE, UniProtKB/TrEMBL
  O55195 ENTREZGENE
  Q5FVT1 ENTREZGENE, UniProtKB/TrEMBL
  Q62796 ENTREZGENE, UniProtKB/Swiss-Prot
UniProt Secondary O55195 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2004-02-26 Ralbp1  ralA binding protein 1    RalA binding protein 1  Symbol and Name status set to approved 625702 APPROVED
2002-08-07 Ralbp1  RalA binding protein 1      Symbol and Name status set to provisional 70820 PROVISIONAL