Sfrp4 Rat Gene (secreted frizzled-related protein 4)

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Keyword

Gene:
Sfrp4 ( Rattus norvegicus )
secreted frizzled-related protein 4
Description: Wnt binding protein involved in modulation of Wnt signaling
ArrayIDs: AF012891_at; GE13168; A_44_P290187; 1388021_at; A_44_P292745; 1368394_at; 6325174; 5635178; rc_AA957779_at; 5913670; 6662874; 5637046; 6324245; 5932068; 6471915; 5690062; 6466285; A_43_P12847;  (details...)
Gene Type: protein-coding

Additional Data

Homologs
Homo sapiens: SFRP4     See the Human gene in context in:     UCSC     NCBI MapViewer

Mus musculus: Sfrp4     See the Mouse gene in context in:     UCSC     NCBI MapViewer

Comparative Map Data
Species Symbol Map Name Chr. Position
Rattus norvegicus Sfrp4 genome assembly 3.1 17 53124265 - 53134348
Rat Celera Assembly 17 51198518 - 51208589
RGSC genome assembly v3.4 17 53121425 - 53131521
Cytogenetic 17 q11
Mus musculus Sfrp4 Mouse genome assembly build 36.1 13 19715052 - 19724690
Cytogenetic 13 13 A2
Homo sapiens SFRP4 human genome assembly 7 37718782 - 37729617
Human genome assembly build 36.2 7 37912068 - 37922902
Cytogenetic 7 p14.1

View comparative maps:      NCBI MapViewer

Genome
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Browsers:

Annotation
Molecular Function

Gene Ontology

Wnt-protein binding,  protein binding (details...)
Biological Process

Gene Ontology

multicellular organismal development,  cell differentiation,  Wnt receptor signaling pathway (details...)
Cellular Component

Gene Ontology

extracellular region (details...)
Regulation

Note Reference

mRNA expression is up-regulated after estrogen treatment in the the pregnant uterus 633927

External Links
Databases
DATABASE ID SOURCE
SMART: C345C IPI
SMART: FRI IPI
PROSITE: FZ IPI
PROSITE: NTR IPI
UNIPARC: UPI00004E18F5 IPI
UNIPARC: UPI00000E86A5 IPI
KEGG Report: rno:89803 ENTREZGENE
HomoloGene Group ID: 2267 ENTREZGENE
Germonline: 621075
Pfam: Fz IPI
Pfam: NTR IPI
KEGG Pathway: 04310 ENTREZGENE
InterPro: Frizzled_Cys-rich. IPI
InterPro: Frizzled-like_dom. IPI
InterPro: Netrin_domain. IPI
InterPro: Frizzled_related. IPI
InterPro: Frizzled_dom_subgr. IPI
InterPro: TIMP-like_OB-fold. IPI
InterPro: Netrin_module_non-TIMP. IPI
IPI: IPI00204890 IPI
IPI: IPI00207235 IPI
Ensembl Protein: ENSRNOP00000059074 IPI
Ensembl Protein: ENSRNOP00000025645 IPI
Gene3D-CATH: Frizzled_Cys-rich IPI
Entrez Gene: Sfrp4 ENTREZGENE
UniProt: SFRP4_RAT IPI
UniProt: Q924N2_RAT IPI
Ensembl Genes: ENSRNOG00000018893 IPI
Superfamily-SCOP: TIMP_like IPI
Superfamily-SCOP: Frizzled_Cys-rich IPI
PANTHER: Fz_related IPI
Sequences
Nucleotide: AF012891 Get FASTA Search GEO Profiles
Nucleotide: AF140347 Get FASTA Search GEO Profiles
Nucleotide: AF220608 Get FASTA Search GEO Profiles
Nucleotide: NM_053544 Get FASTA Search GEO Profiles
Nucleotide: AF140346 Get FASTA Search GEO Profiles
Nucleotide: CH474072 Get FASTA Search GEO Profiles
(View all 6 Nucleotide Accessions)
Protein: NP_445996 Get FASTA
Protein: AAF66481 Get FASTA
Protein: EDL84516 Get FASTA
Protein: EDL84517 Get FASTA
Protein: AAB65431 Get FASTA
Protein: AAF66480 Get FASTA
Protein: AAK58511 Get FASTA
Protein: Q924N2 Get FASTA
Protein: Q9JLS4 Get FASTA
(View all 9 Protein Accessions)
Clusters
UniGene: 10788

References
Curated References
5 references in RGD related to Sfrp4

Other References
7 other references at PubMed related to Sfrp4

Database Information
RGD ID 621075
History

Date Current Symbol Current Name Previous Symbol Previous name Status Description Reference

20-JAN-05: Sfrp4 secreted frizzled-related protein 4 APPROVED Symbol and Name status set to approved 1299863

07-AUG-02: Sfrp4 secreted frizzled-related protein 4 PROVISIONAL Symbol and Name status set to provisional 70820