Tec (tec protein tyrosine kinase) - Rat Genome Database

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Gene: Tec (tec protein tyrosine kinase) Rattus norvegicus
Analyze
Symbol: Tec
Name: tec protein tyrosine kinase
RGD ID: 620973
Description: Predicted to enable non-membrane spanning protein tyrosine kinase activity. Involved in tissue regeneration. Predicted to be located in cell-cell junction and cytoskeleton. Predicted to be active in plasma membrane. Orthologous to human TEC (tec protein tyrosine kinase); PARTICIPATES IN erythropoietin signaling pathway; T cell receptor signaling pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; acetamide.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: cytoplasmic tyrosine kinase; cytoplasmic tyrosine kinase, Dscr28C related; cytoplasmic tyrosine kinase, Dscr28C related (Drosophila); tyrosine-protein kinase Tec
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81435,706,557 - 35,815,563 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1435,691,741 - 35,815,585 (+)EnsemblGRCr8
mRatBN7.21435,352,551 - 35,461,585 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1435,352,829 - 35,461,557 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1435,717,326 - 35,825,852 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01437,022,092 - 37,130,596 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01435,510,436 - 35,618,954 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01437,918,884 - 38,027,953 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1437,918,652 - 38,027,925 (+)Ensemblrn6Rnor6.0
Rnor_5.01437,729,168 - 37,838,252 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41437,756,486 - 37,865,180 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1434,607,791 - 34,715,833 (+)NCBICelera
RGSC_v3.11437,838,323 - 37,868,527 (+)NCBI
Cytogenetic Map14p11NCBI
JBrowse:




Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cell-cell junction  (ISO)
cytoplasm  (IEA)
cytoskeleton  (IEA,ISO)
cytosol  (IEA)
plasma membrane  (IBA,IEA,ISO)

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
4. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
5. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
6. PID Annotation Import Pipeline Pipeline to import Pathway Interaction Database annotations from NCI into RGD
7. GOA pipeline RGD automated data pipeline
8. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
9. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
10. Identification and characterization of differentially expressed genes in the early response phase during liver regeneration. Xu W, etal., Biochem Biophys Res Commun 2000 Nov 19;278(2):318-25.
Additional References at PubMed
PMID:9299487   PMID:9652744   PMID:10518561   PMID:12477932   PMID:21094130   PMID:23793062  


Genomics

Comparative Map Data
Tec
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81435,706,557 - 35,815,563 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1435,691,741 - 35,815,585 (+)EnsemblGRCr8
mRatBN7.21435,352,551 - 35,461,585 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1435,352,829 - 35,461,557 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1435,717,326 - 35,825,852 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01437,022,092 - 37,130,596 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01435,510,436 - 35,618,954 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01437,918,884 - 38,027,953 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1437,918,652 - 38,027,925 (+)Ensemblrn6Rnor6.0
Rnor_5.01437,729,168 - 37,838,252 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41437,756,486 - 37,865,180 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1434,607,791 - 34,715,833 (+)NCBICelera
RGSC_v3.11437,838,323 - 37,868,527 (+)NCBI
Cytogenetic Map14p11NCBI
TEC
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38448,135,783 - 48,269,838 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl448,135,783 - 48,269,858 (-)Ensemblhg38GRCh38
GRCh37448,137,800 - 48,271,855 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36447,832,557 - 47,966,571 (-)NCBIBuild 36Build 36hg18NCBI36
Build 34447,978,728 - 48,112,742NCBI
Celera448,586,515 - 48,720,532 (-)NCBICelera
Cytogenetic Map4p12-p11NCBI
HuRef447,457,565 - 47,591,606 (-)NCBIHuRef
CHM1_1448,136,907 - 48,270,950 (-)NCBICHM1_1
T2T-CHM13v2.0448,102,615 - 48,236,780 (-)NCBIT2T-CHM13v2.0
Tec
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39572,913,061 - 73,025,997 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl572,913,059 - 73,025,826 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm38572,755,718 - 72,868,654 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl572,755,716 - 72,868,483 (-)Ensemblmm10GRCm38
MGSCv37573,146,962 - 73,259,687 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36573,034,873 - 73,147,618 (-)NCBIMGSCv36mm8
Celera570,005,814 - 70,119,901 (-)NCBICelera
Cytogenetic Map5C3.2NCBI
cM Map538.44NCBI
Tec
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955443340,940 - 476,702 (+)Ensembl
ChiLan1.0NW_004955443339,678 - 474,029 (+)NCBIChiLan1.0ChiLan1.0
TEC
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2379,597,405 - 79,732,679 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1479,858,809 - 79,999,701 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0473,885,588 - 74,018,061 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1484,618,088 - 84,750,319 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl484,618,088 - 84,750,319 (+)EnsemblpanPan2panpan1.1
TEC
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11343,978,964 - 44,111,256 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1343,978,573 - 44,062,795 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha1343,931,930 - 44,063,497 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.01344,579,240 - 44,711,903 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1344,578,650 - 44,711,864 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11344,256,721 - 44,388,235 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01343,788,809 - 43,921,144 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01344,671,707 - 44,803,644 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Tec
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440528531,945,875 - 32,049,975 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493648214,248,233 - 14,341,402 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_00493648214,248,277 - 14,341,329 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TEC
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl838,051,059 - 38,181,874 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1838,051,053 - 38,182,259 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2840,100,495 - 40,275,177 (-)NCBISscrofa10.2Sscrofa10.2susScr3
TEC
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1271,982,549 - 2,118,533 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl272,024,719 - 2,117,763 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366604747,991,627 - 48,131,736 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Tec
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462476118,695,177 - 18,822,078 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462476118,695,168 - 18,824,045 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Tec
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v11129,565,334 - 29,629,230 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Tec
1175 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:76
Count of miRNA genes:56
Interacting mature miRNAs:74
Transcripts:ENSRNOT00000003125
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
631528Scl11Serum cholesterol level QTL 114.9blood cholesterol amount (VT:0000180)blood total cholesterol level (CMO:0000051)141787564536079022Rat
7411573Bw139Body weight QTL 1394.70.001body mass (VT:0001259)body weight gain (CMO:0000420)14140068101Rat
9589814Gluco67Glucose level QTL 674.540.001blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)14140068101Rat
731183Pia20Pristane induced arthritis QTL 203.55joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)14939329839411170Rat
1300154Bp189Blood pressure QTL 1893.04arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)143123808072970315Rat
70187Pancm5Pancreatic morphology QTL 516.7pancreas mass (VT:0010144)pancreas weight to body weight ratio (CMO:0000630)143067446985041098Rat
2324617Coatc2Coat color QTL 20.001coat/hair pigmentation trait (VT:0010463)pigmented coat/hair area to total coat/hair area ratio (CMO:0001810)143112133339507682Rat
631523Pia13Pristane induced arthritis QTL 133.3joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1433424686102238540Rat
1358296Ael3Aortic elastin QTL 33.70.00051aorta elastin amount (VT:0003905)aortic elastin14862139853621398Rat
61420Pia6Pristane induced arthritis QTL 64.9joint integrity trait (VT:0010548)arthritic paw count (CMO:0001460)141891545442433608Rat
7387267Uae42Urinary albumin excretion QTL 420.61urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)142252151767521517Rat
631839Niddm37Non-insulin dependent diabetes mellitus QTL 373.37blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)1411334716100078267Rat
2313397Coatc1Coat color QTL1coat/hair pigmentation trait (VT:0010463)coat/hair color measurement (CMO:0001808)141889519263895192Rat
631262Tcas4Tongue tumor susceptibility QTL 47.29tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)141790672654251504Rat
634352Apr6Acute phase response QTL 63.7blood interleukin-6 amount (VT:0008595)plasma interleukin-6 level (CMO:0001927)14141415516Rat
2302045Pia39Pristane induced arthritis QTL 394.90.001blood immunoglobulin amount (VT:0002460)serum immunoglobulin G2a level (CMO:0002116)14862139853621398Rat

Markers in Region
D14Got44  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21435,442,032 - 35,442,185 (+)MAPPERmRatBN7.2
Rnor_6.01438,008,403 - 38,008,555NCBIRnor6.0
Rnor_5.01437,818,685 - 37,818,837UniSTSRnor5.0
RGSC_v3.41437,845,655 - 37,845,808RGDRGSC3.4
RGSC_v3.41437,845,656 - 37,845,808UniSTSRGSC3.4
Celera1434,696,308 - 34,696,463UniSTS
RGSC_v3.11437,848,980 - 37,849,133RGD
Cytogenetic Map14p11UniSTS
RH144023  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21435,409,966 - 35,410,230 (+)MAPPERmRatBN7.2
Rnor_6.01437,976,338 - 37,976,601NCBIRnor6.0
Rnor_5.01437,786,425 - 37,786,688UniSTSRnor5.0
RGSC_v3.41437,813,591 - 37,813,854UniSTSRGSC3.4
Celera1434,664,807 - 34,665,070UniSTS
Cytogenetic Map14p11UniSTS
RH141346  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21435,461,158 - 35,461,338 (+)MAPPERmRatBN7.2
Rnor_6.01438,027,527 - 38,027,706NCBIRnor6.0
Rnor_5.01437,837,826 - 37,838,005UniSTSRnor5.0
RGSC_v3.41437,864,780 - 37,864,959UniSTSRGSC3.4
Celera1434,715,433 - 34,715,612UniSTS
Cytogenetic Map14p11UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
17 13 80 208 91 90 59 131 59 6 433 252 20 188 97 124 31 28 28

Sequence


Ensembl Acc Id: ENSRNOT00000003125   ⟹   ENSRNOP00000003125
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1435,706,890 - 35,815,583 (+)Ensembl
mRatBN7.2 Ensembl1435,352,863 - 35,461,557 (+)Ensembl
Rnor_6.0 Ensembl1437,919,233 - 38,027,925 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000088441   ⟹   ENSRNOP00000075313
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1435,706,836 - 35,815,585 (+)Ensembl
mRatBN7.2 Ensembl1435,352,829 - 35,461,557 (+)Ensembl
Rnor_6.0 Ensembl1437,918,652 - 38,027,920 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000097152   ⟹   ENSRNOP00000084561
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1435,706,890 - 35,815,583 (+)Ensembl
mRatBN7.2 Ensembl1435,352,863 - 35,461,557 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000105424   ⟹   ENSRNOP00000082206
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1435,706,890 - 35,815,583 (+)Ensembl
mRatBN7.2 Ensembl1435,352,863 - 35,461,557 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000109580   ⟹   ENSRNOP00000085542
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1435,691,741 - 35,815,585 (+)Ensembl
mRatBN7.2 Ensembl1435,352,863 - 35,461,406 (+)Ensembl
RefSeq Acc Id: NM_053432   ⟹   NP_445884
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81435,706,870 - 35,815,563 (+)NCBI
mRatBN7.21435,352,863 - 35,461,559 (+)NCBI
Rnor_6.01437,919,233 - 38,027,927 (+)NCBI
Rnor_5.01437,729,168 - 37,838,252 (+)NCBI
RGSC_v3.41437,756,486 - 37,865,180 (+)RGD
Celera1434,607,791 - 34,715,833 (+)RGD
Sequence:
RefSeq Acc Id: XM_039092512   ⟹   XP_038948440
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81435,706,853 - 35,815,563 (+)NCBI
mRatBN7.21435,352,860 - 35,461,585 (+)NCBI
RefSeq Acc Id: XM_039092513   ⟹   XP_038948441
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81435,706,864 - 35,813,903 (+)NCBI
mRatBN7.21435,352,854 - 35,459,903 (+)NCBI
RefSeq Acc Id: XM_039092514   ⟹   XP_038948442
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81435,750,483 - 35,815,563 (+)NCBI
mRatBN7.21435,396,506 - 35,461,585 (+)NCBI
RefSeq Acc Id: XM_063273683   ⟹   XP_063129753
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81435,706,862 - 35,815,563 (+)NCBI
RefSeq Acc Id: XM_063273684   ⟹   XP_063129754
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81435,729,780 - 35,815,563 (+)NCBI
RefSeq Acc Id: XM_063273685   ⟹   XP_063129755
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81435,706,557 - 35,815,563 (+)NCBI
RefSeq Acc Id: XM_063273686   ⟹   XP_063129756
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81435,750,483 - 35,815,563 (+)NCBI
RefSeq Acc Id: NP_445884   ⟸   NM_053432
- UniProtKB: B2RYC7 (UniProtKB/TrEMBL),   A0A8I5ZXG2 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000003125   ⟸   ENSRNOT00000003125
Ensembl Acc Id: ENSRNOP00000075313   ⟸   ENSRNOT00000088441
RefSeq Acc Id: XP_038948441   ⟸   XM_039092513
- Peptide Label: isoform X4
RefSeq Acc Id: XP_038948440   ⟸   XM_039092512
- Peptide Label: isoform X2
- UniProtKB: B2RYC7 (UniProtKB/TrEMBL),   A0A8I5ZXG2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038948442   ⟸   XM_039092514
- Peptide Label: isoform X5
- UniProtKB: Q9EQ78 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000084561   ⟸   ENSRNOT00000097152
Ensembl Acc Id: ENSRNOP00000082206   ⟸   ENSRNOT00000105424
Ensembl Acc Id: ENSRNOP00000085542   ⟸   ENSRNOT00000109580
RefSeq Acc Id: XP_063129755   ⟸   XM_063273685
- Peptide Label: isoform X1
- UniProtKB: A0A8I5ZXG2 (UniProtKB/TrEMBL),   A0A8I6A3K6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063129753   ⟸   XM_063273683
- Peptide Label: isoform X1
- UniProtKB: A0A8I5ZXG2 (UniProtKB/TrEMBL),   A0A8I6A3K6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063129754   ⟸   XM_063273684
- Peptide Label: isoform X1
- UniProtKB: A0A8I5ZXG2 (UniProtKB/TrEMBL),   A0A8I6A3K6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063129756   ⟸   XM_063273686
- Peptide Label: isoform X3
- UniProtKB: Q9EQ78 (UniProtKB/TrEMBL)
Protein Domains
PH   Protein kinase   SH2   SH3

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-A0A0G2KA94-F1-model_v2 AlphaFold A0A0G2KA94 1-674 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13699300
Promoter ID:EPDNEW_R9821
Type:multiple initiation site
Name:Tec_2
Description:tec protein tyrosine kinase
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_R9822  
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01437,918,621 - 37,918,681EPDNEW
RGD ID:13699297
Promoter ID:EPDNEW_R9822
Type:multiple initiation site
Name:Tec_1
Description:tec protein tyrosine kinase
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_R9821  
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01437,919,237 - 37,919,297EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:620973 AgrOrtholog
BioCyc Gene G2FUF-15856 BioCyc
Ensembl Genes ENSRNOG00000002278 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000003125 ENTREZGENE
  ENSRNOT00000003125.7 UniProtKB/TrEMBL
  ENSRNOT00000088441 ENTREZGENE
  ENSRNOT00000088441.3 UniProtKB/TrEMBL
  ENSRNOT00000097152.2 UniProtKB/TrEMBL
  ENSRNOT00000105424.2 UniProtKB/TrEMBL
  ENSRNOT00000109580.2 UniProtKB/TrEMBL
Gene3D-CATH 2.30.29.30 UniProtKB/TrEMBL
  3.30.505.10 UniProtKB/TrEMBL
  SH3 Domains UniProtKB/TrEMBL
  Transferase(Phosphotransferase) domain 1 UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7934247 IMAGE-MGC_LOAD
InterPro Kinase-like_dom UniProtKB/TrEMBL
  Non-receptor_tyrosine_kinases UniProtKB/TrEMBL
  PH_like_dom UniProtKB/TrEMBL
  Pleckstrin_homology UniProtKB/TrEMBL
  Prot_kinase_cat_dom UniProtKB/TrEMBL
  Protein_kinase_ATP_BS UniProtKB/TrEMBL
  Ser-Thr/Tyr-Pkinase UniProtKB/TrEMBL
  SH2 UniProtKB/TrEMBL
  SH2_dom_sf UniProtKB/TrEMBL
  SH3-like_dom UniProtKB/TrEMBL
  SH3_domain UniProtKB/TrEMBL
  Tec_SH3 UniProtKB/TrEMBL
  Tyr_Pkinase_cat_dom UniProtKB/TrEMBL
  Tyr_prot_kinase_AS UniProtKB/TrEMBL
  Znf_Btk_motif UniProtKB/TrEMBL
KEGG Report rno:84492 UniProtKB/TrEMBL
MGC_CLONE MGC:188447 IMAGE-MGC_LOAD
NCBI Gene 84492 ENTREZGENE
PANTHER TYROSINE-PROTEIN KINASE UniProtKB/TrEMBL
Pfam BTK UniProtKB/TrEMBL
  PF00169 UniProtKB/TrEMBL
  Pkinase_Tyr UniProtKB/TrEMBL
  SH2 UniProtKB/TrEMBL
  SH3_1 UniProtKB/TrEMBL
PhenoGen Tec PhenoGen
PIRSF TyrPK_CSF1-R UniProtKB/TrEMBL
PRINTS SH2DOMAIN UniProtKB/TrEMBL
  SH3DOMAIN UniProtKB/TrEMBL
  TECBTKDOMAIN UniProtKB/TrEMBL
  TYRKINASE UniProtKB/TrEMBL
PROSITE PH_DOMAIN UniProtKB/TrEMBL
  PROTEIN_KINASE_ATP UniProtKB/TrEMBL
  PROTEIN_KINASE_DOM UniProtKB/TrEMBL
  PROTEIN_KINASE_TYR UniProtKB/TrEMBL
  SH2 UniProtKB/TrEMBL
  SH3 UniProtKB/TrEMBL
  ZF_BTK UniProtKB/TrEMBL
RatGTEx ENSRNOG00000002278 RatGTEx
SMART BTK UniProtKB/TrEMBL
  SH2 UniProtKB/TrEMBL
  SH3 UniProtKB/TrEMBL
  SM00233 UniProtKB/TrEMBL
  TyrKc UniProtKB/TrEMBL
Superfamily-SCOP Kinase_like UniProtKB/TrEMBL
  PH domain-like UniProtKB/TrEMBL
  SH3 UniProtKB/TrEMBL
  SSF55550 UniProtKB/TrEMBL
UniProt A0A0G2KA94_RAT UniProtKB/TrEMBL
  A0A8I5ZXG2 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6A3K6 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6GBZ8_RAT UniProtKB/TrEMBL
  A6JD61_RAT UniProtKB/TrEMBL
  B2RYC7 ENTREZGENE, UniProtKB/TrEMBL
  Q9EQ78 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-10-23 Tec  tec protein tyrosine kinase  Tec  cytoplasmic tyrosine kinase, Dscr28C related (Drosophila)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-02-22 Tec  cytoplasmic tyrosine kinase, Dscr28C related (Drosophila)  Tec  tec protein tyrosine kinase  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2002-08-07 Tec  tec protein tyrosine kinase      Symbol and Name status set to provisional 70820 PROVISIONAL

RGD Curation Notes
Note Type Note Reference
gene_expression expressed exclusively in liver 631955
gene_regulation induced in regeneration liver; induced by EGF 631955