Tec (tec protein tyrosine kinase) - Rat Genome Database

Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Gene: Tec (tec protein tyrosine kinase) Rattus norvegicus
Analyze
Symbol: Tec
Name: tec protein tyrosine kinase
RGD ID: 620973
Description: Predicted to enable non-membrane spanning protein tyrosine kinase activity. Involved in tissue regeneration. Predicted to be located in cell-cell junction and cytoskeleton. Predicted to be active in plasma membrane. Orthologous to human TEC (tec protein tyrosine kinase); PARTICIPATES IN erythropoietin signaling pathway; T cell receptor signaling pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; acetamide.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: cytoplasmic tyrosine kinase; cytoplasmic tyrosine kinase, Dscr28C related; cytoplasmic tyrosine kinase, Dscr28C related (Drosophila); tyrosine-protein kinase Tec
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81435,706,557 - 35,815,563 (+)NCBIGRCr8
mRatBN7.21435,352,551 - 35,461,585 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1435,352,829 - 35,461,557 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1435,717,326 - 35,825,852 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01437,022,092 - 37,130,596 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01435,510,436 - 35,618,954 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01437,918,884 - 38,027,953 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1437,918,652 - 38,027,925 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01437,729,168 - 37,838,252 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41437,756,486 - 37,865,180 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11437,838,323 - 37,868,527 (+)NCBI
Celera1434,607,791 - 34,715,833 (+)NCBICelera
Cytogenetic Map14p11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


1 to 20 of 72 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
TecRat(-)-epigallocatechin 3-gallate multiple interactionsISOTEC (Homo sapiens)6480464[potassium chromate(VI) co-treated with epigallocatechin gallate] results in decreased expression of TEC mRNACTDPMID:22079256
TecRat(1->4)-beta-D-glucan multiple interactionsISOTec (Mus musculus)6480464[perfluorooctane sulfonic acid co-treated with Cellulose] results in decreased expression of TEC mRNACTDPMID:36331819
TecRat1,2-dimethylhydrazine increases expressionISOTec (Mus musculus)64804641 and 2-Dimethylhydrazine results in increased expression of TEC mRNACTDPMID:22206623
TecRat2,3,7,8-tetrachlorodibenzodioxine decreases expressionISOTec (Mus musculus)6480464Tetrachlorodibenzodioxin results in decreased expression of TEC mRNACTDPMID:19933214
TecRat2,3,7,8-tetrachlorodibenzodioxine increases expressionEXP 6480464Tetrachlorodibenzodioxin results in increased expression of TEC mRNACTDPMID:33387578
TecRat2,3,7,8-tetrachlorodibenzodioxine multiple interactionsISOTec (Mus musculus)6480464[TIPARP gene mutant form results in increased susceptibility to Tetrachlorodibenzodioxin] which results in increased expression of TEC mRNACTDPMID:25975270
TecRat2,3,7,8-tetrachlorodibenzodioxine affects expressionISOTec (Mus musculus)6480464Tetrachlorodibenzodioxin affects the expression of TEC mRNACTDPMID:21570461
TecRat2,3,7,8-tetrachlorodibenzodioxine decreases expressionEXP 6480464Tetrachlorodibenzodioxin results in decreased expression of TEC mRNACTDPMID:21215274 and PMID:32109520
TecRat2,3,7,8-tetrachlorodibenzodioxine affects expressionEXP 6480464Tetrachlorodibenzodioxin affects the expression of TEC mRNACTDPMID:22298810 and PMID:34747641
TecRat2-hydroxypropanoic acid decreases expressionISOTEC (Homo sapiens)6480464Lactic Acid results in decreased expression of TEC mRNACTDPMID:30851411
TecRat4,4'-diaminodiphenylmethane decreases expressionISOTec (Mus musculus)64804644 and 4'-diaminodiphenylmethane results in decreased expression of TEC mRNACTDPMID:18648102
TecRat4,4'-sulfonyldiphenol increases expressionISOTec (Mus musculus)6480464bisphenol S results in increased expression of TEC mRNACTDPMID:30951980
TecRat4,4'-sulfonyldiphenol decreases methylationISOTec (Mus musculus)6480464bisphenol S results in decreased methylation of TEC promoterCTDPMID:33297965
TecRat6-propyl-2-thiouracil increases expressionEXP 6480464Propylthiouracil results in increased expression of TEC mRNACTDPMID:24780913
TecRatacetamide decreases expressionEXP 6480464acetamide results in decreased expression of TEC mRNACTDPMID:31881176
TecRatacrylamide increases expressionISOTec (Mus musculus)6480464Acrylamide results in increased expression of TEC mRNACTDPMID:30807115
TecRataflatoxin B1 increases methylationISOTEC (Homo sapiens)6480464Aflatoxin B1 results in increased methylation of TEC geneCTDPMID:27153756
TecRataflatoxin B1 decreases methylationISOTEC (Homo sapiens)6480464Aflatoxin B1 results in decreased methylation of TEC intronCTDPMID:30157460
TecRatammonium chloride affects expressionEXP 6480464Ammonium Chloride affects the expression of TEC mRNACTDPMID:16483693
TecRatbenzo[a]pyrene multiple interactionsISOTec (Mus musculus)6480464[Benzo(a)pyrene co-treated with benz(a)anthracene co-treated with benzo(b)fluoranthene co-treated with chrysene] results in increased expression of TEC mRNACTDPMID:27858113

1 to 20 of 72 rows

Biological Process
1 to 11 of 11 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
TecRatadaptive immune response involved_inIBAMGI:102960 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
TecRatB cell receptor signaling pathway involved_inISOTEC (Homo sapiens)1624291 PMID:10518561RGDPMID:10518561
TecRatB cell receptor signaling pathway involved_inIEAUniProtKB:P42680 and ensembl:ENSP000003709121600115GO_REF:0000107EnsemblGO_REF:0000107
TecRatB cell receptor signaling pathway involved_inIBAPANTHER:PTN000700360 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
TecRatintegrin-mediated signaling pathway involved_inISOTEC (Homo sapiens)1624291 PMID:9652744RGDPMID:9652744
TecRatintegrin-mediated signaling pathway involved_inIEAUniProtKB:P42680 and ensembl:ENSP000003709121600115GO_REF:0000107EnsemblGO_REF:0000107
TecRatintracellular signal transduction involved_inIEAInterPro:IPR0015621600115GO_REF:0000002InterProGO_REF:0000002
TecRatregulation of platelet activation involved_inIEAUniProtKB:P42680 and ensembl:ENSP000003709121600115GO_REF:0000107EnsemblGO_REF:0000107
TecRatregulation of platelet activation involved_inISOTEC (Homo sapiens)1624291 PMID:9299487 and PMID:9652744RGDPMID:9299487 and PMID:9652744
TecRatT cell receptor signaling pathway involved_inIBAMGI:102960 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
TecRattissue regeneration  IEP 631955 RGD 
1 to 11 of 11 rows

Cellular Component
1 to 9 of 9 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
TecRatcell-cell junction located_inISOTec (Mus musculus)1624291 PMID:23793062RGDPMID:23793062
TecRatcytoplasm located_inIEAUniProtKB-KW:KW-09631600115GO_REF:0000043UniProtGO_REF:0000043
TecRatcytoplasm located_inIEAUniProtKB-SubCell:SL-00861600115GO_REF:0000044UniProtGO_REF:0000044
TecRatcytoskeleton located_inISOTEC (Homo sapiens)1624291 PMID:9299487 and PMID:9652744RGDPMID:9299487 and PMID:9652744
TecRatcytoskeleton located_inIEAUniProtKB:P42680 and ensembl:ENSP000003709121600115GO_REF:0000107EnsemblGO_REF:0000107
TecRatcytosol located_inIEAARBA:ARBA000292431600115GO_REF:0000117UniProtGO_REF:0000117
TecRatplasma membrane located_inISOTEC (Homo sapiens)1624291 RGDGO_REF:0000052
TecRatplasma membrane is_active_inIBAFB:FBgn0000017 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
TecRatplasma membrane located_inIEAUniProtKB:P42680 and ensembl:ENSP000003709121600115GO_REF:0000107EnsemblGO_REF:0000107
1 to 9 of 9 rows

Molecular Function
1 to 20 of 20 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
TecRatATP binding enablesIEAUniRule:UR0015033411600115GO_REF:0000104UniProtGO_REF:0000104
TecRatATP binding enablesIEAInterPro:IPR000719 and InterPro:IPR0174411600115GO_REF:0000002InterProGO_REF:0000002
TecRatATP binding enablesIEAUniProtKB-KW:KW-00671600115GO_REF:0000043UniProtGO_REF:0000043
TecRatkinase activity enablesIEAUniProtKB-KW:KW-04181600115GO_REF:0000043UniProtGO_REF:0000043
TecRatmetal ion binding enablesIEAUniProtKB-KW:KW-04791600115GO_REF:0000043UniProtGO_REF:0000043
TecRatnon-membrane spanning protein tyrosine kinase activity enablesISOTEC (Homo sapiens)1624291 PMID:10518561RGDPMID:10518561
TecRatnon-membrane spanning protein tyrosine kinase activity enablesIEAEC:2.7.10.21600115GO_REF:0000003UniProtGO_REF:0000003
TecRatnon-membrane spanning protein tyrosine kinase activity enablesIBAPANTHER:PTN001231474 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
TecRatnon-membrane spanning protein tyrosine kinase activity enablesIEAUniProtKB:P42680 and ensembl:ENSP000003709121600115GO_REF:0000107EnsemblGO_REF:0000107
TecRatnucleotide binding enablesIEAUniRule:UR0015033411600115GO_REF:0000104UniProtGO_REF:0000104
TecRatnucleotide binding enablesIEAUniProtKB-KW:KW-05471600115GO_REF:0000043UniProtGO_REF:0000043
TecRatprotein binding enablesISOTEC (Homo sapiens)1624291UniProtKB:P08581 more ...RGDPMID:10518561 more ...
TecRatprotein binding enablesISOTec (Mus musculus)1624291PR:Q9JM90 more ...RGDPMID:11716489 and PMID:23478294
TecRatprotein kinase activity enablesIEAInterPro:IPR000719 more ...1600115GO_REF:0000002InterProGO_REF:0000002
TecRatprotein tyrosine kinase activity enablesIEAARBA:ARBA000276311600115GO_REF:0000117UniProtGO_REF:0000117
TecRatprotein tyrosine kinase activity enablesIEARHEA:105961600115GO_REF:0000116RHEAGO_REF:0000116
TecRatprotein tyrosine kinase activity enablesIEAInterPro:IPR0206351600115GO_REF:0000002InterProGO_REF:0000002
TecRatprotein tyrosine kinase activity enablesIEAUniProtKB-KW:KW-08291600115GO_REF:0000043UniProtGO_REF:0000043
TecRattransferase activity enablesIEAUniProtKB-KW:KW-08081600115GO_REF:0000043UniProtGO_REF:0000043
TecRatzinc ion binding enablesIEAUniProtKB-KW:KW-08631600115GO_REF:0000043UniProtGO_REF:0000043
1 to 20 of 20 rows

Imported Annotations - KEGG (archival)

Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
TecRatT cell receptor signaling pathway  IEA 6907045 KEGGrno:04660

Imported Annotations - PID (archival)

Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
TecRaterythropoietin signaling pathway  ISOTEC (Homo sapiens)6484113 PIDPID:200183

1 to 10 of 10 rows
#
Reference Title
Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
4. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
5. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
6. PID Annotation Import Pipeline Pipeline to import Pathway Interaction Database annotations from NCI into RGD
7. GOA pipeline RGD automated data pipeline
8. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
9. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
10. Identification and characterization of differentially expressed genes in the early response phase during liver regeneration. Xu W, etal., Biochem Biophys Res Commun 2000 Nov 19;278(2):318-25.
1 to 10 of 10 rows
PMID:9299487   PMID:9652744   PMID:10518561   PMID:12477932   PMID:21094130   PMID:23793062  



Tec
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81435,706,557 - 35,815,563 (+)NCBIGRCr8
mRatBN7.21435,352,551 - 35,461,585 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1435,352,829 - 35,461,557 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1435,717,326 - 35,825,852 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01437,022,092 - 37,130,596 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01435,510,436 - 35,618,954 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01437,918,884 - 38,027,953 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1437,918,652 - 38,027,925 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01437,729,168 - 37,838,252 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41437,756,486 - 37,865,180 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11437,838,323 - 37,868,527 (+)NCBI
Celera1434,607,791 - 34,715,833 (+)NCBICelera
Cytogenetic Map14p11NCBI
TEC
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38448,135,783 - 48,269,838 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl448,135,783 - 48,269,838 (-)EnsemblGRCh38hg38GRCh38
GRCh37448,137,800 - 48,271,855 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36447,832,557 - 47,966,571 (-)NCBINCBI36Build 36hg18NCBI36
Build 34447,978,728 - 48,112,742NCBI
Celera448,586,515 - 48,720,532 (-)NCBICelera
Cytogenetic Map4p12-p11NCBI
HuRef447,457,565 - 47,591,606 (-)NCBIHuRef
CHM1_1448,136,907 - 48,270,950 (-)NCBICHM1_1
T2T-CHM13v2.0448,102,615 - 48,236,780 (-)NCBIT2T-CHM13v2.0
Tec
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39572,913,061 - 73,025,997 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl572,913,059 - 73,025,826 (-)EnsemblGRCm39 Ensembl
GRCm38572,755,718 - 72,868,654 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl572,755,716 - 72,868,483 (-)EnsemblGRCm38mm10GRCm38
MGSCv37573,146,962 - 73,259,687 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36573,034,873 - 73,147,618 (-)NCBIMGSCv36mm8
Celera570,005,814 - 70,119,901 (-)NCBICelera
Cytogenetic Map5C3.2NCBI
cM Map538.44NCBI
Tec
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955443340,940 - 476,702 (+)EnsemblChiLan1.0
ChiLan1.0NW_004955443339,678 - 474,029 (+)NCBIChiLan1.0ChiLan1.0
TEC
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2379,597,405 - 79,732,679 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1479,858,809 - 79,999,701 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0473,885,588 - 74,018,061 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1484,618,088 - 84,750,319 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl484,618,088 - 84,750,319 (+)Ensemblpanpan1.1panPan2
TEC
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11343,978,964 - 44,111,256 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1343,978,573 - 44,062,795 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1343,931,930 - 44,063,497 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01344,579,240 - 44,711,903 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1344,578,650 - 44,711,864 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11344,256,721 - 44,388,235 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01343,788,809 - 43,921,144 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01344,671,707 - 44,803,644 (-)NCBIUU_Cfam_GSD_1.0
Tec
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440528531,945,875 - 32,049,975 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493648214,248,233 - 14,341,402 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493648214,248,277 - 14,341,329 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TEC
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl838,051,059 - 38,181,874 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1838,051,053 - 38,182,259 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2840,100,495 - 40,275,177 (-)NCBISscrofa10.2Sscrofa10.2susScr3
TEC
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1271,982,549 - 2,118,533 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl272,024,719 - 2,117,763 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604747,991,627 - 48,131,736 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Tec
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462476118,695,177 - 18,822,078 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462476118,695,168 - 18,824,045 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

.

.
Variants in Tec
920 total Variants

Predicted Target Of
Summary Value
Count of predictions:76
Count of miRNA genes:56
Interacting mature miRNAs:74
Transcripts:ENSRNOT00000003125
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


1 to 10 of 15 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
1581500Renag1Renal agenesis QTL 1kidney development trait (VT:0000527)percentage of study population developing unilateral renal agenesis during a period of time (CMO:0000940)14817066868298175Rat
731183Pia20Pristane induced arthritis QTL 203.55joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)14908897839057237Rat
10755459Coatc15Coat color QTL 150.01681coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)141983694464836944Rat
1300154Bp189Blood pressure QTL 1893.04arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)143088377768757901Rat
70187Pancm5Pancreatic morphology QTL 516.7pancreas mass (VT:0010144)pancreas weight to body weight ratio (CMO:0000630)143032009280829842Rat
2324617Coatc2Coat color QTL 20.001coat/hair pigmentation trait (VT:0010463)pigmented coat/hair area to total coat/hair area ratio (CMO:0001810)143076702539153750Rat
1358296Ael3Aortic elastin QTL 33.70.00051aorta elastin amount (VT:0003905)aortic elastin14826709053267090Rat
71117Niddm17Non-insulin dependent diabetes mellitus QTL 172.35blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)141759376142336881Rat
61420Pia6Pristane induced arthritis QTL 64.9joint integrity trait (VT:0010548)arthritic paw count (CMO:0001460)141863134542337007Rat
7387267Uae42Urinary albumin excretion QTL 420.61urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)142216796767167967Rat

1 to 10 of 15 rows
D14Got44  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21435,442,032 - 35,442,185 (+)MAPPERmRatBN7.2
Rnor_6.01438,008,403 - 38,008,555NCBIRnor6.0
Rnor_5.01437,818,685 - 37,818,837UniSTSRnor5.0
RGSC_v3.41437,845,655 - 37,845,808RGDRGSC3.4
RGSC_v3.41437,845,656 - 37,845,808UniSTSRGSC3.4
RGSC_v3.11437,848,980 - 37,849,133RGD
Celera1434,696,308 - 34,696,463UniSTS
Cytogenetic Map14p11UniSTS
RH144023  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21435,409,966 - 35,410,230 (+)MAPPERmRatBN7.2
Rnor_6.01437,976,338 - 37,976,601NCBIRnor6.0
Rnor_5.01437,786,425 - 37,786,688UniSTSRnor5.0
RGSC_v3.41437,813,591 - 37,813,854UniSTSRGSC3.4
Celera1434,664,807 - 34,665,070UniSTS
Cytogenetic Map14p11UniSTS
RH141346  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21435,461,158 - 35,461,338 (+)MAPPERmRatBN7.2
Rnor_6.01438,027,527 - 38,027,706NCBIRnor6.0
Rnor_5.01437,837,826 - 37,838,005UniSTSRnor5.0
RGSC_v3.41437,864,780 - 37,864,959UniSTSRGSC3.4
Celera1434,715,433 - 34,715,612UniSTS
Cytogenetic Map14p11UniSTS




alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31



Ensembl Acc Id: ENSRNOT00000003125   ⟹   ENSRNOP00000003125
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1435,352,863 - 35,461,557 (+)Ensembl
Rnor_6.0 Ensembl1437,919,233 - 38,027,925 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000088441   ⟹   ENSRNOP00000075313
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1435,352,829 - 35,461,557 (+)Ensembl
Rnor_6.0 Ensembl1437,918,652 - 38,027,920 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000097152   ⟹   ENSRNOP00000084561
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1435,352,863 - 35,461,557 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000105424   ⟹   ENSRNOP00000082206
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1435,352,863 - 35,461,557 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000109580   ⟹   ENSRNOP00000085542
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1435,352,863 - 35,461,406 (+)Ensembl
RefSeq Acc Id: NM_053432   ⟹   NP_445884
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81435,706,870 - 35,815,563 (+)NCBI
mRatBN7.21435,352,863 - 35,461,559 (+)NCBI
Rnor_6.01437,919,233 - 38,027,927 (+)NCBI
Rnor_5.01437,729,168 - 37,838,252 (+)NCBI
RGSC_v3.41437,756,486 - 37,865,180 (+)RGD
Celera1434,607,791 - 34,715,833 (+)RGD
Sequence:
RefSeq Acc Id: XM_039092512   ⟹   XP_038948440
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81435,706,853 - 35,815,563 (+)NCBI
mRatBN7.21435,352,860 - 35,461,585 (+)NCBI
RefSeq Acc Id: XM_039092513   ⟹   XP_038948441
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81435,706,864 - 35,813,903 (+)NCBI
mRatBN7.21435,352,854 - 35,459,903 (+)NCBI
RefSeq Acc Id: XM_039092514   ⟹   XP_038948442
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81435,750,483 - 35,815,563 (+)NCBI
mRatBN7.21435,396,506 - 35,461,585 (+)NCBI
RefSeq Acc Id: XM_063273683   ⟹   XP_063129753
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81435,706,862 - 35,815,563 (+)NCBI
RefSeq Acc Id: XM_063273684   ⟹   XP_063129754
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81435,729,780 - 35,815,563 (+)NCBI
RefSeq Acc Id: XM_063273685   ⟹   XP_063129755
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81435,706,557 - 35,815,563 (+)NCBI
RefSeq Acc Id: XM_063273686   ⟹   XP_063129756
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81435,750,483 - 35,815,563 (+)NCBI
1 to 5 of 13 rows
1 to 5 of 13 rows
RefSeq Acc Id: NP_445884   ⟸   NM_053432
- UniProtKB: B2RYC7 (UniProtKB/TrEMBL),   A0A8I5ZXG2 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000003125   ⟸   ENSRNOT00000003125
Ensembl Acc Id: ENSRNOP00000075313   ⟸   ENSRNOT00000088441
RefSeq Acc Id: XP_038948441   ⟸   XM_039092513
- Peptide Label: isoform X4
RefSeq Acc Id: XP_038948440   ⟸   XM_039092512
- Peptide Label: isoform X2
- UniProtKB: B2RYC7 (UniProtKB/TrEMBL),   A0A8I5ZXG2 (UniProtKB/TrEMBL)
PH   Protein kinase   SH2   SH3

Name Modeler Protein Id AA Range Protein Structure
AF-A0A0G2KA94-F1-model_v2 AlphaFold A0A0G2KA94 1-674 view protein structure


eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

RGD ID:13699300
Promoter ID:EPDNEW_R9821
Type:multiple initiation site
Name:Tec_2
Description:tec protein tyrosine kinase
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_R9822  
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01437,918,621 - 37,918,681EPDNEW
RGD ID:13699297
Promoter ID:EPDNEW_R9822
Type:multiple initiation site
Name:Tec_1
Description:tec protein tyrosine kinase
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_R9821  
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01437,919,237 - 37,919,297EPDNEW


1 to 40 of 68 rows
Database
Acc Id
Source(s)
BioCyc Gene G2FUF-15856 BioCyc
Ensembl Genes ENSRNOG00000002278 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000003125 ENTREZGENE
  ENSRNOT00000003125.6 UniProtKB/TrEMBL
  ENSRNOT00000088441 ENTREZGENE
  ENSRNOT00000088441.2 UniProtKB/TrEMBL
  ENSRNOT00000097152.1 UniProtKB/TrEMBL
  ENSRNOT00000105424.1 UniProtKB/TrEMBL
  ENSRNOT00000109580.1 UniProtKB/TrEMBL
Gene3D-CATH 2.30.29.30 UniProtKB/TrEMBL
  3.30.505.10 UniProtKB/TrEMBL
  SH3 Domains UniProtKB/TrEMBL
  Transferase(Phosphotransferase) domain 1 UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7934247 IMAGE-MGC_LOAD
InterPro Kinase-like_dom UniProtKB/TrEMBL
  Non-receptor_tyrosine_kinases UniProtKB/TrEMBL
  PH_like_dom UniProtKB/TrEMBL
  Pleckstrin_homology UniProtKB/TrEMBL
  Prot_kinase_cat_dom UniProtKB/TrEMBL
  Protein_kinase_ATP_BS UniProtKB/TrEMBL
  Ser-Thr/Tyr-Pkinase UniProtKB/TrEMBL
  SH2 UniProtKB/TrEMBL
  SH2_dom_sf UniProtKB/TrEMBL
  SH3-like_dom UniProtKB/TrEMBL
  SH3_domain UniProtKB/TrEMBL
  Tec_SH3 UniProtKB/TrEMBL
  Tyr_Pkinase_cat_dom UniProtKB/TrEMBL
  Tyr_prot_kinase_AS UniProtKB/TrEMBL
  Znf_Btk_motif UniProtKB/TrEMBL
KEGG Report rno:84492 UniProtKB/TrEMBL
MGC_CLONE MGC:188447 IMAGE-MGC_LOAD
NCBI Gene 84492 ENTREZGENE
PANTHER TYROSINE-PROTEIN KINASE UniProtKB/TrEMBL
Pfam BTK UniProtKB/TrEMBL
  PF00169 UniProtKB/TrEMBL
  Pkinase_Tyr UniProtKB/TrEMBL
  SH2 UniProtKB/TrEMBL
  SH3_1 UniProtKB/TrEMBL
PhenoGen Tec PhenoGen
PIRSF TyrPK_CSF1-R UniProtKB/TrEMBL
1 to 40 of 68 rows


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-10-23 Tec  tec protein tyrosine kinase  Tec  cytoplasmic tyrosine kinase, Dscr28C related (Drosophila)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-02-22 Tec  cytoplasmic tyrosine kinase, Dscr28C related (Drosophila)  Tec  tec protein tyrosine kinase  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2002-08-07 Tec  tec protein tyrosine kinase      Symbol and Name status set to provisional 70820 PROVISIONAL

Note Type Note Reference
gene_expression expressed exclusively in liver 631955
gene_regulation induced in regeneration liver; induced by EGF 631955