TEC (tec protein tyrosine kinase)

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Keyword

Gene: TEC (tec protein tyrosine kinase) Homo sapiens

Symbol:

TEC

Name:

tec protein tyrosine kinase

Description:

The protein encoded by this gene belongs to the Tec family of non-receptor protein-tyrosine kinases containing a pleckstrin homology domain. Tec family kinases are involved in the intracellular signaling mechanisms of cytokine receptors, lymphocyte surface antigens, heterotrimeric G-protein coupled receptors, and integrin molecules. They are also key players in the regulation of the immune functions. Tec kinase is an integral component of T cell signaling and has a distinct role in T cell activation. This gene may be associated with myelodysplastic syndrome. [provided by RefSeq, Jul 2008]

Type:

protein-coding

RefSeq Status:

REVIEWED

Also known as:

MGC126760; MGC126762; OTTHUMP00000158787; PSCTK4; tyrosine-protein kinase Tec

Orthologs:

Mus musculus : Tec (tec protein tyrosine kinase) MGI
Rattus norvegicus : Tec (tec protein tyrosine kinase)

Latest Assembly:

Human Genome Assembly GRCh37

Position:

Map	Chr	Position	Strand	Source
Human Alternate Assembly CHM1_1	4	48,019,101 - 48,153,014	-	NCBI
Human Genome Assembly HuRef	4	47,457,565 - 47,591,606	-	NCBI
Human Genome Assembly GRCh37	4	48,137,800 - 48,271,814	-	NCBI
Human Genome Assembly Build 36	4	47,832,557 - 47,966,571	-	NCBI
Human Cytogenetic Map	4	p12		NCBI
Human Genome Assembly	4	47,978,728 - 48,112,742		NCBI