Rab10 (RAB10, member RAS oncogene family) - Rat Genome Database

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Gene: Rab10 (RAB10, member RAS oncogene family) Rattus norvegicus
Analyze
Symbol: Rab10
Name: RAB10, member RAS oncogene family
RGD ID: 620879
Description: Enables GDP-dissociation inhibitor binding activity and myosin V binding activity. Involved in Golgi to plasma membrane transport; cellular response to antibiotic; and generation of neurons. Located in cilium; perinuclear region of cytoplasm; and trans-Golgi network. Is active in synaptic vesicle membrane. Orthologous to human RAB10 (RAB10, member RAS oncogene family); PARTICIPATES IN insulin responsive facilitative sugar transporter mediated glucose transport pathway; Rab family mediated signaling pathway; INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,4,6-trinitrobenzenesulfonic acid.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: Ac1075; ras-related protein Rab-10; ras-related protein rab10
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8631,974,858 - 32,039,554 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl631,986,921 - 32,039,733 (-)EnsemblGRCr8
mRatBN7.2626,267,081 - 26,319,739 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl626,266,859 - 26,320,193 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx626,559,705 - 26,612,364 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0626,875,588 - 26,928,242 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0626,353,848 - 26,406,629 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0627,668,387 - 27,721,120 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl627,668,403 - 27,721,120 (-)Ensemblrn6Rnor6.0
Rnor_5.0637,479,058 - 37,531,622 (-)NCBIRnor_5.0Rnor_5.0rn5
Celera625,743,962 - 25,796,212 (-)NCBICelera
RGSC_v3.1626,260,312 - 26,297,639NCBI
Cytogenetic Map6q14NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,2-dichloroethane  (ISO)
1,2-dimethylhydrazine  (ISO)
17beta-estradiol  (EXP,ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4,6-trinitrobenzenesulfonic acid  (EXP)
2,4-dinitrotoluene  (EXP)
2-methylcholine  (ISO)
3,3',5,5'-tetrabromobisphenol A  (ISO)
3H-1,2-dithiole-3-thione  (EXP)
4,4'-sulfonyldiphenol  (EXP)
4-amino-2,6-dinitrotoluene  (EXP)
aconitine  (EXP)
acrylamide  (ISO)
actinomycin D  (ISO)
aflatoxin B1  (ISO)
ammonium chloride  (EXP)
Aroclor 1254  (ISO)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
bisphenol A  (EXP,ISO)
bisphenol AF  (ISO)
Bisphenol B  (ISO)
bisphenol F  (EXP)
Bufotalin  (ISO)
cadmium dichloride  (EXP)
carbon nanotube  (ISO)
carboplatin  (EXP)
chlorpyrifos  (ISO)
chromium(6+)  (ISO)
copper atom  (ISO)
copper(0)  (ISO)
copper(II) sulfate  (ISO)
cyclosporin A  (ISO)
decabromodiphenyl ether  (ISO)
dibutyl phthalate  (EXP)
dimethylarsinic acid  (EXP)
doxorubicin  (EXP,ISO)
ethanol  (EXP,ISO)
finasteride  (EXP)
flutamide  (EXP)
folic acid  (ISO)
FR900359  (ISO)
gentamycin  (EXP)
haloperidol  (EXP)
hydrogen peroxide  (ISO)
hypochlorous acid  (ISO)
ivermectin  (ISO)
methyl methanesulfonate  (ISO)
N,N-diethyl-m-toluamide  (EXP)
nickel atom  (ISO)
nitrates  (ISO)
Nutlin-3  (ISO)
ozone  (EXP)
paracetamol  (EXP,ISO)
permethrin  (EXP)
resveratrol  (ISO)
sodium arsenate  (ISO)
sodium arsenite  (ISO)
sodium fluoride  (ISO)
sulforaphane  (ISO)
tetrachloromethane  (ISO)
titanium dioxide  (ISO)
trichloroethene  (EXP)
trimellitic anhydride  (ISO)
valproic acid  (ISO)
vinclozolin  (EXP)
zoledronic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Rab10 associates with primary cilia and the exocyst complex in renal epithelial cells. Babbey CM, etal., Am J Physiol Renal Physiol. 2010 Sep;299(3):F495-506. doi: 10.1152/ajprenal.00198.2010. Epub 2010 Jun 24.
2. Expression and localization of two low molecular weight GTP-binding proteins, Rab8 and Rab10, by epitope tag. Chen YT, etal., Proc Natl Acad Sci U S A 1993 Jul 15;90(14):6508-12.
3. rab15, a novel low molecular weight GTP-binding protein specifically expressed in rat brain. Elferink LA, etal., J Biol Chem 1992 Mar 25;267(9):5768-75.
4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
5. Rab proteins in endocytosis and Glut4 trafficking. Kaddai V, etal., Acta Physiol (Oxf). 2008 Jan;192(1):75-88.
6. Signal transduction meets vesicle traffic: the software and hardware of GLUT4 translocation. Klip A, etal., Am J Physiol Cell Physiol. 2014 May 15;306(10):C879-86. doi: 10.1152/ajpcell.00069.2014. Epub 2014 Mar 5.
7. The GLUT4 code. Larance M, etal., Mol Endocrinol. 2008 Feb;22(2):226-33. Epub 2007 Aug 23.
8. Myosin Vb controls biogenesis of post-Golgi Rab10 carriers during axon development. Liu Y, etal., Nat Commun. 2013;4:2005. doi: 10.1038/ncomms3005.
9. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
10. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
11. Quantitative analysis of synaptic vesicle Rabs uncovers distinct yet overlapping roles for Rab3a and Rab27b in Ca2+-triggered exocytosis. Pavlos NJ, etal., J Neurosci. 2010 Oct 6;30(40):13441-53. doi: 10.1523/JNEUROSCI.0907-10.2010.
12. GOA pipeline RGD automated data pipeline
13. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
14. Comprehensive gene review and curation RGD comprehensive gene curation
15. Hepatic interferon regulatory factor 8 expression mediates liver ischemia/reperfusion injury in mice. Shi G, etal., Biochem Pharmacol. 2021 Oct;192:114728. doi: 10.1016/j.bcp.2021.114728. Epub 2021 Aug 13.
16. Lgl1 activation of rab10 promotes axonal membrane trafficking underlying neuronal polarization. Wang T, etal., Dev Cell. 2011 Sep 13;21(3):431-44. doi: 10.1016/j.devcel.2011.07.007.
17. GLUT4 translocation: the last 200 nanometers. Watson RT and Pessin JE, Cell Signal. 2007 Nov;19(11):2209-17. Epub 2007 Jun 21.
18. Insulin action on glucose transporters through molecular switches, tracks and tethers. Zaid H, etal., Biochem J. 2008 Jul 15;413(2):201-15.
Additional References at PubMed
PMID:2732579   PMID:11042173   PMID:12477932   PMID:16641372   PMID:17132146   PMID:17403373   PMID:18504258   PMID:19056867   PMID:19717423   PMID:20458337   PMID:20937701   PMID:21423176  
PMID:22908308   PMID:23263280   PMID:23533145   PMID:24006491   PMID:24478353   PMID:24662485   PMID:24891604   PMID:25468996   PMID:27354378   PMID:29476059   PMID:31505169  


Genomics

Comparative Map Data
Rab10
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8631,974,858 - 32,039,554 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl631,986,921 - 32,039,733 (-)EnsemblGRCr8
mRatBN7.2626,267,081 - 26,319,739 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl626,266,859 - 26,320,193 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx626,559,705 - 26,612,364 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0626,875,588 - 26,928,242 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0626,353,848 - 26,406,629 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0627,668,387 - 27,721,120 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl627,668,403 - 27,721,120 (-)Ensemblrn6Rnor6.0
Rnor_5.0637,479,058 - 37,531,622 (-)NCBIRnor_5.0Rnor_5.0rn5
Celera625,743,962 - 25,796,212 (-)NCBICelera
RGSC_v3.1626,260,312 - 26,297,639NCBI
Cytogenetic Map6q14NCBI
RAB10
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38226,033,285 - 26,137,454 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl226,033,481 - 26,138,436 (+)Ensemblhg38GRCh38
GRCh37226,256,953 - 26,360,323 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36226,110,478 - 26,213,782 (+)NCBIBuild 36Build 36hg18NCBI36
Build 34226,168,624 - 26,271,929NCBI
Celera226,097,002 - 26,200,567 (+)NCBICelera
Cytogenetic Map2p23.3NCBI
HuRef225,993,019 - 26,096,921 (+)NCBIHuRef
CHM1_1226,186,807 - 26,290,405 (+)NCBICHM1_1
T2T-CHM13v2.0226,069,400 - 26,172,749 (+)NCBIT2T-CHM13v2.0
Rab10
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39123,297,428 - 3,359,969 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl123,297,428 - 3,359,969 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm38123,247,428 - 3,309,969 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl123,247,428 - 3,309,969 (-)Ensemblmm10GRCm38
MGSCv37123,247,428 - 3,309,969 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36123,247,726 - 3,309,939 (-)NCBIMGSCv36mm8
Celera123,174,851 - 3,237,418 (-)NCBICelera
Cytogenetic Map12A1.1NCBI
cM Map121.71NCBI
Rab10
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554698,057,235 - 8,138,983 (+)Ensembl
ChiLan1.0NW_0049554698,057,235 - 8,138,983 (+)NCBIChiLan1.0ChiLan1.0
RAB10
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v212100,381,221 - 100,485,143 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12A100,385,189 - 100,488,306 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02A26,034,046 - 26,132,658 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12A26,125,984 - 26,228,505 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2A26,125,985 - 26,228,505 (+)EnsemblpanPan2panpan1.1
RAB10
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11720,181,363 - 20,264,927 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1720,181,363 - 20,264,927 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha1720,077,187 - 20,160,857 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.01720,503,635 - 20,587,796 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1720,503,607 - 20,589,813 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11720,190,180 - 20,274,283 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01720,200,321 - 20,284,230 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01720,247,131 - 20,331,947 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Rab10
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440629264,488,453 - 64,575,695 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364936,263,863 - 6,351,327 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049364936,263,870 - 6,351,327 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
RAB10
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl3112,829,137 - 112,924,269 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.13112,842,190 - 112,924,188 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.23119,827,428 - 119,909,414 (-)NCBISscrofa10.2Sscrofa10.2susScr3
RAB10
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11481,508,800 - 81,618,172 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1481,507,031 - 81,617,983 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366604530,540,276 - 30,649,087 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Rab10
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247388,212,355 - 8,294,423 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046247388,212,401 - 8,294,307 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Rab10
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v1723,956,895 - 24,012,032 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Rab10
249 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:275
Count of miRNA genes:171
Interacting mature miRNAs:219
Transcripts:ENSRNOT00000071425
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
8552962Pigfal16Plasma insulin-like growth factor 1 level QTL 169.4blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)6197587946975879Rat
10401812Kidm54Kidney mass QTL 54kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)62009763565097635Rat
8552910Pigfal5Plasma insulin-like growth factor 1 level QTL 54.3blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)62265388967653889Rat
10401800Kidm49Kidney mass QTL 49kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)62009763565097635Rat
1300164Rf15Renal function QTL 153.12renal blood flow trait (VT:2000006)absolute change in renal blood flow rate (CMO:0001168)6323998948239989Rat
1331779Rf38Renal function QTL 382.876kidney blood vessel physiology trait (VT:0100012)absolute change in renal vascular resistance (CMO:0001900)63118500276185002Rat
9589129Insul24Insulin level QTL 2419.060.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)6197587946975879Rat
7411603Foco13Food consumption QTL 135.50.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)6197587946975879Rat
1598843Cm63Cardiac mass QTL 632.6heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)6144788383Rat
7411542Bw127Body weight QTL 1275.50.001body mass (VT:0001259)body weight gain (CMO:0000420)6197587946975879Rat
2292616Ept15Estrogen-induced pituitary tumorigenesis QTL 154.4pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)6144788383Rat
9589048Scfw3Subcutaneous fat weight QTL 34.570.001subcutaneous adipose mass (VT:1000472)abdominal subcutaneous fat pad weight (CMO:0002069)6197587946975879Rat
2293839Kiddil2Kidney dilation QTL 24.8kidney pelvis morphology trait (VT:0004194)hydronephrosis severity score (CMO:0001208)62661831486868070Rat
1576309Emca7Estrogen-induced mammary cancer QTL 74mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)620859430113082285Rat
2301964Bp323Blood pressure QTL 3234.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)6186868070Rat
2293709Bss23Bone structure and strength QTL 235.180.0001femur morphology trait (VT:0000559)femur cross-sectional area (CMO:0001661)6323998948239989Rat
2293650Bss31Bone structure and strength QTL 315.050.0001femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)6323998948239989Rat
2293841Kiddil4Kidney dilation QTL 44.4kidney pelvis morphology trait (VT:0004194)hydronephrosis severity score (CMO:0001208)62661831486868070Rat
1300128Rf16Renal function QTL 163.89renal blood flow trait (VT:2000006)absolute change in renal blood flow rate (CMO:0001168)6140163351Rat
1641898Colcr4Colorectal carcinoma resistance QTL43.710.0007intestine integrity trait (VT:0010554)well differentiated malignant colorectal tumor surface area measurement (CMO:0002077)63093763275937632Rat
70199Coreg1Compensatory renal growth QTL 111.8kidney mass (VT:0002707)compensatory renal growth score (CMO:0001894)61459947363457687Rat
2301972Bp325Blood pressure QTL 3254.8arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)61608937261967788Rat
1358190Ept1Estrogen-induced pituitary tumorigenesis QTL 14.4pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)6144788383Rat
2293656Bss28Bone structure and strength QTL 286.790.0001femur morphology trait (VT:0000559)femur midshaft cortical cross-sectional area (CMO:0001663)6323998948239989Rat
1359023Bp272Blood pressure QTL 2722.5arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)62228825732981219Rat
1354664Slep2Serum leptin concentration QTL 24.49blood leptin amount (VT:0005667)serum leptin level (CMO:0000780)62228825767288257Rat

Markers in Region
BI283356  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2626,267,200 - 26,267,405 (+)MAPPERmRatBN7.2
Rnor_6.0627,668,507 - 27,668,711NCBIRnor6.0
Rnor_5.0637,479,178 - 37,479,382UniSTSRnor5.0
Celera625,744,082 - 25,744,286UniSTS
RH 3.4 Map6118.2UniSTS
Cytogenetic Map6q12UniSTS
BF393954  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2626,285,386 - 26,285,553 (+)MAPPERmRatBN7.2
Rnor_6.0627,686,682 - 27,686,848NCBIRnor6.0
Rnor_5.0637,497,184 - 37,497,350UniSTSRnor5.0
RGSC_v3.4626,257,916 - 26,258,082UniSTSRGSC3.4
Celera625,761,930 - 25,762,096UniSTS
RH 3.4 Map6118.19UniSTS
Cytogenetic Map6q12UniSTS
AU048675  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2626,313,990 - 26,314,190 (+)MAPPERmRatBN7.2
Rnor_6.0627,715,372 - 27,715,571NCBIRnor6.0
Rnor_5.0637,525,874 - 37,526,073UniSTSRnor5.0
RGSC_v3.4626,288,785 - 26,288,984UniSTSRGSC3.4
Celera625,790,473 - 25,790,661UniSTS
Cytogenetic Map6q12UniSTS
RAB10_1045  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2626,266,838 - 26,267,720 (+)MAPPERmRatBN7.2
Rnor_6.0627,668,145 - 27,669,026NCBIRnor6.0
Rnor_5.0637,478,816 - 37,479,697UniSTSRnor5.0
Celera625,743,720 - 25,744,601UniSTS
Cytogenetic Map6q12UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 165 91 90 59 92 59 6 356 192 11 144 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000071425   ⟹   ENSRNOP00000065234
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl631,986,921 - 32,039,733 (-)Ensembl
mRatBN7.2 Ensembl626,266,859 - 26,320,193 (-)Ensembl
Rnor_6.0 Ensembl627,668,403 - 27,721,120 (-)Ensembl
RefSeq Acc Id: NM_017359   ⟹   NP_059055
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8631,986,905 - 32,039,554 (-)NCBI
mRatBN7.2626,267,081 - 26,319,739 (-)NCBI
Rnor_6.0627,668,387 - 27,721,120 (-)NCBI
Rnor_5.0637,479,058 - 37,531,622 (-)NCBI
Celera625,743,962 - 25,796,212 (-)RGD
Sequence:
RefSeq Acc Id: XM_063262358   ⟹   XP_063118428
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8631,974,858 - 32,039,550 (-)NCBI
RefSeq Acc Id: NP_059055   ⟸   NM_017359
- UniProtKB: P35281 (UniProtKB/Swiss-Prot),   Q5RKJ9 (UniProtKB/TrEMBL),   M0R717 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000065234   ⟸   ENSRNOT00000071425
RefSeq Acc Id: XP_063118428   ⟸   XM_063262358
- Peptide Label: isoform X1
- UniProtKB: P35281 (UniProtKB/Swiss-Prot)

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P35281-F1-model_v2 AlphaFold P35281 1-200 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:620879 AgrOrtholog
BioCyc Gene G2FUF-38299 BioCyc
Ensembl Genes ENSRNOG00000047088 Ensembl, ENTREZGENE
Ensembl Transcript ENSRNOT00000071425 ENTREZGENE
Gene3D-CATH 3.40.50.300 UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:7191921 IMAGE-MGC_LOAD
InterPro P-loop_NTPase UniProtKB/Swiss-Prot
  Small_GTP-bd_dom UniProtKB/Swiss-Prot
  Small_GTPase UniProtKB/Swiss-Prot
  Small_GTPase_Rab UniProtKB/Swiss-Prot
MGC_CLONE MGC:93509 IMAGE-MGC_LOAD
NCBI Gene 50993 ENTREZGENE
PANTHER LD44762P UniProtKB/Swiss-Prot
Pfam Ras UniProtKB/Swiss-Prot
PhenoGen Rab10 PhenoGen
PRINTS RASTRNSFRMNG UniProtKB/Swiss-Prot
PROSITE RAB UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000047088 RatGTEx
SMART RAB UniProtKB/Swiss-Prot
  RAN UniProtKB/Swiss-Prot
  RAS UniProtKB/Swiss-Prot
  RHO UniProtKB/Swiss-Prot
Superfamily-SCOP SSF52540 UniProtKB/Swiss-Prot
UniProt A6HAF0_RAT UniProtKB/TrEMBL
  M0R717 ENTREZGENE, UniProtKB/TrEMBL
  P35281 ENTREZGENE
  Q5RKJ9 ENTREZGENE, UniProtKB/TrEMBL
  RAB10_RAT UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2004-09-10 Rab10  RAB10, member RAS oncogene family    ras-related protein rab10  Name updated 1299863 APPROVED
2002-08-07 Rab10  ras-related protein rab10      Symbol and Name status set to provisional 70820 PROVISIONAL

RGD Curation Notes
Note Type Note Reference
gene_cellular_localization localized to membranes in the perinuclear region, possibly to the Golgi apparatus 734514