Advanced Search (OLGA)

Gene: Polr1b (RNA polymerase I subunit B) Rattus norvegicus

Analyze

Symbol:

Polr1b

Name:

RNA polymerase I subunit B

RGD ID:

620822

Description:

Contributes to DNA-directed RNA polymerase activity. Involved in rRNA transcription. Part of RNA polymerase I complex. Human ortholog(s) of this gene implicated in Treacher Collins syndrome 4. Orthologous to human POLR1B (RNA polymerase I subunit B); PARTICIPATES IN RNA polymerase I transcription pathway; purine metabolic pathway; pyrimidine metabolic pathway; INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

A127; DNA-directed RNA polymerase I subunit RPA2; polymerase (RNA) I polypeptide B; polymerase (RNA) I subunit B; RNA polymerase 1-2; RNA polymerase I (127 kDa subunit); RNA polymerase I polypeptide B; RNA polymerase I subunit 2; RPA135; RPA2; Rpo1-2

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	POLR1B (RNA polymerase I subunit B)	HGNC	Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther
Mus musculus (house mouse):	Polr1b (polymerase (RNA) I polypeptide B)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Polr1b (RNA polymerase I subunit B)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	POLR1B (RNA polymerase I subunit B)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	POLR1B (RNA polymerase I subunit B)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Polr1b (RNA polymerase I subunit B)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	POLR1B (RNA polymerase I subunit B)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	POLR1B (RNA polymerase I subunit B)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Polr1b (RNA polymerase I subunit B)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus rattus (black rat):	Polr1b (RNA polymerase I subunit B)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Other homologs ²
Homo sapiens (human):	LDLRAD4 (low density lipoprotein receptor class A domain containing 4)	HGNC	OMA
Alliance orthologs ³
Mus musculus (house mouse):	Polr1b (polymerase (RNA) I polypeptide B)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Homo sapiens (human):	POLR1B (RNA polymerase I subunit B)	Alliance	DIOPT (HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	polr1b (RNA polymerase I subunit B)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Caenorhabditis elegans (roundworm):	rpoa-2	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Caenorhabditis elegans (roundworm):	rpoa-2	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Saccharomyces cerevisiae (baker's yeast):	RPA135	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	RpI135	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	polr1b	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	polr1b	Alliance	DIOPT (Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	3	136,787,130 - 136,811,608 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	3	136,787,107 - 136,811,607 (+)	Ensembl				GRCr8
mRatBN7.2	3	116,333,910 - 116,358,385 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	3	116,333,889 - 116,358,379 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	3	120,231,013 - 120,255,438 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	3	128,826,598 - 128,851,016 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	3	126,487,078 - 126,511,500 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	3	121,632,043 - 121,656,506 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	3	121,632,043 - 121,656,506 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	3	128,358,264 - 128,382,727 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	3	116,706,483 - 116,730,946 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	3	115,159,305 - 115,183,765 (+)	NCBI		Celera
RGSC_v3.1	3	116,612,055 - 116,636,519 (+)	NCBI
Cytogenetic Map	3	q36	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Mandibulofacial Dysostosis (ISO)

Treacher Collins syndrome (ISO)

Treacher Collins syndrome 4 (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(+)-schisandrin B (EXP)

(-)-alpha-phellandrene (ISO)

1,2-dimethylhydrazine (ISO)

17beta-estradiol (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP)

2,4-dinitrotoluene (EXP)

4,4'-diaminodiphenylmethane (ISO)

aflatoxin B1 (ISO)

all-trans-retinoic acid (EXP,ISO)

alpha-phellandrene (ISO)

ammonium chloride (EXP)

amphetamine (EXP)

antirheumatic drug (ISO)

arsane (ISO)

arsenic atom (ISO)

atrazine (ISO)

benzo[a]pyrene (ISO)

benzo[a]pyrene diol epoxide I (ISO)

beta-hexachlorocyclohexane (ISO)

bis(2-chloroethyl) sulfide (ISO)

bisphenol A (EXP,ISO)

bisphenol F (ISO)

cadmium dichloride (ISO)

carbon nanotube (ISO)

chlorpyrifos (ISO)

chromium(6+) (ISO)

copper(II) sulfate (ISO)

cordycepin (ISO)

coumestrol (ISO)

DDE (ISO)

Dibutyl phosphate (ISO)

dimethyl sulfoxide (ISO)

dioxygen (ISO)

doxorubicin (ISO)

ethyl methanesulfonate (ISO)

flavonoids (EXP)

flutamide (EXP)

formaldehyde (ISO)

gentamycin (EXP)

hydrogen peroxide (ISO)

hydroquinone (ISO)

Indeno[1,2,3-cd]pyrene (ISO)

ivermectin (ISO)

lead(0) (ISO)

maneb (ISO)

methotrexate (ISO)

methyl methanesulfonate (ISO)

methylmercury chloride (ISO)

N-nitrosodiethylamine (EXP)

nickel atom (ISO)

nitroglycerin (EXP)

ochratoxin A (ISO)

paracetamol (ISO)

paraquat (EXP,ISO)

perfluorooctanoic acid (EXP,ISO)

phenobarbital (EXP)

pirinixic acid (ISO)

pregnenolone 16alpha-carbonitrile (ISO)

progesterone (ISO)

silicon dioxide (ISO)

sodium arsenite (ISO)

sodium dichromate (EXP)

sunitinib (ISO)

testosterone (ISO)

tetrachloromethane (EXP)

tetraphene (ISO)

theophylline (ISO)

thioacetamide (EXP)

thiram (ISO)

titanium dioxide (ISO)

toluene 2,4-diisocyanate (ISO)

Tributyltin oxide (ISO)

trimellitic anhydride (ISO)

triphenyl phosphate (ISO)

urethane (ISO)

valproic acid (ISO)

vinclozolin (EXP)

vincristine (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

DNA-templated transcription (IEA)

embryo implantation (ISO)

neural crest formation (ISS)

nucleologenesis (ISO)

rRNA transcription (IDA,IEA,ISO)

transcription elongation by RNA polymerase I (IBA,IEA,ISO)

Cellular Component

chromosome (IEA,ISO,ISS)

DNA-directed RNA polymerase complex (IEA)

fibrillar center (IEA,ISO)

nucleolus (IEA,ISO)

nucleus (IEA,ISO)

RNA polymerase I complex (IBA,IDA,IEA,ISO)

Molecular Function

5'-3' RNA polymerase activity (IEA)

DNA binding (IEA)

DNA-directed RNA polymerase activity (IBA,IDA,IEA,ISO)

DNA/RNA hybrid binding (IEA,ISO)

metal ion binding (IEA)

nucleotidyltransferase activity (IEA)

protein binding (ISO)

ribonucleoside binding (IEA)

transferase activity (IEA)

zinc ion binding (IEA,ISO)

Molecular Pathway Annotations Click to see Annotation Detail View

purine metabolic pathway (IEA)

pyrimidine metabolic pathway (IEA)

RNA polymerase I transcription pathway (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	Affinity purification of mammalian RNA polymerase I. Identification of an associated kinase.	Hannan RD, etal., J Biol Chem. 1998 Jan 9;273(2):1257-67.
3.	KEGG: Kyoto Encyclopedia of Genes and Genomes	KEGG
4.	Rat ISS GO annotations from MGI mouse gene data--August 2006	MGD data from the GO Consortium
5.	Electronic Transfer of LocusLink and RefSeq Data	NCBI rat LocusLink and RefSeq merged data July 26, 2002
6.	KEGG Annotation Import Pipeline	Pipeline to import KEGG annotations from KEGG into RGD
7.	GOA pipeline	RGD automated data pipeline
8.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
9.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
10.	Comprehensive gene review and curation	RGD comprehensive gene curation
11.	RNA polymerase I activity is regulated at multiple steps in the transcription cycle: recent insights into factors that influence transcription elongation.	Schneider DA Gene. 2012 Feb 10;493(2):176-84. doi: 10.1016/j.gene.2011.08.006. Epub 2011 Aug 26.
12.	Molecular cloning of RPA2, the gene encoding the second largest subunit of mouse RNA polymerase I.	Seither P and Grummt I, Genomics 1996 Oct 1;37(1):135-9.
13.	Conservation between the RNA polymerase I, II, and III transcription initiation machineries.	Vannini A and Cramer P, Mol Cell. 2012 Feb 24;45(4):439-46. doi: 10.1016/j.molcel.2012.01.023.

Additional References at PubMed

PMID:9236775	PMID:11592397	PMID:18023416

Genomics

Comparative Map Data

Polr1b
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	3	136,787,130 - 136,811,608 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	3	136,787,107 - 136,811,607 (+)	Ensembl				GRCr8
mRatBN7.2	3	116,333,910 - 116,358,385 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	3	116,333,889 - 116,358,379 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	3	120,231,013 - 120,255,438 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	3	128,826,598 - 128,851,016 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	3	126,487,078 - 126,511,500 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	3	121,632,043 - 121,656,506 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	3	121,632,043 - 121,656,506 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	3	128,358,264 - 128,382,727 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	3	116,706,483 - 116,730,946 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	3	115,159,305 - 115,183,765 (+)	NCBI		Celera
RGSC_v3.1	3	116,612,055 - 116,636,519 (+)	NCBI
Cytogenetic Map	3	q36	NCBI

POLR1B
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	2	112,542,036 - 112,579,818 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	2	112,541,915 - 112,579,818 (+)	Ensembl			hg38	GRCh38
GRCh37	2	113,299,613 - 113,337,395 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	2	113,016,084 - 113,051,879 (+)	NCBI	Build 36	Build 36	hg18	NCBI36
Build 34	2	113,015,843 - 113,051,639	NCBI
Celera	2	106,685,049 - 106,720,277 (+)	NCBI		Celera
Cytogenetic Map	2	q14.1	NCBI
HuRef	2	105,754,007 - 105,789,231 (+)	NCBI		HuRef
CHM1_1	2	113,303,652 - 113,338,870 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	2	112,968,686 - 113,006,450 (+)	NCBI		T2T-CHM13v2.0

Polr1b
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	2	128,942,891 - 128,969,980 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	2	128,942,915 - 128,968,514 (+)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	2	129,100,970 - 129,128,060 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	2	129,100,995 - 129,126,594 (+)	Ensembl			mm10	GRCm38
MGSCv37	2	128,926,732 - 128,952,331 (+)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	2	128,792,479 - 128,818,036 (+)	NCBI		MGSCv36	mm8
Celera	2	130,328,366 - 130,353,838 (+)	NCBI		Celera
Cytogenetic Map	2	F1	NCBI
cM Map	2	62.68	NCBI

Polr1b
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955470	1,714,156 - 1,737,820 (-)	Ensembl
ChiLan1.0	NW_004955470	1,714,156 - 1,737,749 (-)	NCBI	ChiLan1.0	ChiLan1.0

POLR1B
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	12	15,545,294 - 15,588,412 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	2A	15,548,058 - 15,584,608 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	2A	89,478,133 - 89,516,559 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	2A	113,555,452 - 113,590,377 (+)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	2A	113,555,452 - 113,590,377 (+)	Ensembl			panPan2	panpan1.1

POLR1B
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	17	36,774,472 - 36,798,900 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	17	36,774,541 - 36,797,525 (+)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	17	36,543,712 - 36,568,761 (+)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	17	37,550,047 - 37,575,002 (+)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	17	37,545,667 - 37,575,002 (+)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	17	36,688,159 - 36,713,214 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	17	36,742,224 - 36,767,072 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	17	36,956,099 - 36,980,996 (+)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Polr1b
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024406292	82,139,613 - 82,161,453 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936783	1,034,054 - 1,056,384 (+)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936783	1,034,097 - 1,055,798 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

POLR1B
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	3	43,950,002 - 43,975,683 (-)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	3	43,949,032 - 43,974,283 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	3	45,544,060 - 45,568,445 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

POLR1B
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	14	15,549,963 - 15,585,947 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	14	15,550,254 - 15,584,521 (+)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM
Vero_WHO_p1.0	NW_023666080	4,095,537 - 4,131,082 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Polr1b
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624749	12,602,004 - 12,625,200 (+)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
HetGla 1.0	NW_004624749	12,602,078 - 12,625,200 (+)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Polr1b
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	5	107,871,216 - 107,894,762 (+)	NCBI		Rrattus_CSIRO_v1

Variants

Variants in Polr1b
407 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	59
Count of miRNA genes:	47
Interacting mature miRNAs:	55
Transcripts:	ENSRNOT00000024882
Prediction methods:	Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1582233	Insul10	Insulin level QTL 10	5.4	0.0015	blood insulin amount (VT:0001560)	serum insulin level times blood glucose level (CMO:0002040)	3	133259579	178259579	Rat
2301414	Kidm37	Kidney mass QTL 37		0.001	kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	3	96509147	141509147	Rat
2302373	Gluco39	Glucose level QTL 39	5.01		blood glucose amount (VT:0000188)	blood glucose level area under curve (AUC) (CMO:0000350)	3	129154923	182114333	Rat
70216	Cm14	Cardiac mass QTL 14	2.1		heart mass (VT:0007028)	heart wet weight (CMO:0000069)	3	51581665	184004958	Rat
2292591	Esta4	Estrogen-induced thymic atrophy QTL 4			thymus mass (VT:0004954)	thymus wet weight (CMO:0000855)	3	67641776	167835660	Rat
1358362	Srcrt2	Stress Responsive Cort QTL 2	2.78		blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	3	58601291	153936591	Rat
737818	Hcar12	Hepatocarcinoma resistance QTL 12	2.6		liver integrity trait (VT:0010547)	volume of individual liver tumorous lesion (CMO:0001078)	3	49872657	138829559	Rat
7387306	Bw124	Body weight QTL 124	3.2	0.0003	body mass (VT:0001259)	body weight (CMO:0000012)	3	104545086	149545086	Rat
1578754	Stresp16	Stress response QTL 16	4	0.001	blood renin amount (VT:0003349)	plasma renin activity level (CMO:0000116)	3	133134628	178134628	Rat
1300111	Rf12	Renal function QTL 12	3.78		renal blood flow trait (VT:2000006)	absolute change in renal blood flow rate (CMO:0001168)	3	81425008	141509147	Rat
1600376	Arunc5	Aerobic running capacity QTL 5		0.21	exercise endurance trait (VT:0002332)	longest distance run on treadmill (CMO:0001406)	3	93829559	138829559	Rat
8694437	Bw167	Body weight QTL 167	22.46	0.001	retroperitoneal fat pad mass (VT:0010430)	retroperitoneal fat pad weight to body weight ratio (CMO:0000635)	3	112250810	157250810	Rat
8662816	Vetf4	Vascular elastic tissue fragility QTL 4	4		renal artery integrity trait (VT:0010642)	number of ruptures of the internal elastic lamina of the renal arteries (CMO:0002563)	3	79649560	177741895	Rat
1581503	Cm58	Cardiac mass QTL 58	2.7	0.05	heart left ventricle mass (VT:0007031)	heart left ventricle weight to body weight ratio (CMO:0000530)	3	96509147	141509147	Rat
1354611	Despr2	Despair related QTL 2	3.03	0.0028	locomotor behavior trait (VT:0001392)	amount of time spent in voluntary immobility (CMO:0001043)	3	117537367	162537367	Rat
2303620	Vencon4	Ventilatory control QTL 4	3.9		respiration trait (VT:0001943)	tidal volume (CMO:0000222)	3	125116475	170116475	Rat
631649	Bp123	Blood pressure QTL 123	3.2		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	3	110225882	155225882	Rat
1358204	Insglur1	Insulin/glucose ratio QTL 1	3.8		blood glucose amount (VT:0000188)	serum glucose level (CMO:0000543)	3	136091420	155634702	Rat
12879848	Bw181	Body weght QTL 181		0.015	body mass (VT:0001259)	body weight (CMO:0000012)	3	90755164	141509147	Rat
5686842	Rf59	Renal function QTL 59			urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	3	122395989	167395989	Rat
2301971	Cm71	Cardiac mass QTL 71	4.63		heart left ventricle mass (VT:0007031)	heart left ventricle weight (CMO:0000776)	3	131036586	176036586	Rat
1358885	Bp251	Blood pressure QTL 251	3.8		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	3	1	141509147	Rat
2301970	Bw81	Body weight QTL 81	5.19		body mass (VT:0001259)	body weight (CMO:0000012)	3	131036586	176036586	Rat
1581546	Pur13	Proteinuria QTL 13	2.93	0.0335	urine total protein amount (VT:0000032)	urine protein excretion rate (CMO:0000759)	3	98651826	167012663	Rat
631665	Bw8	Body weight QTL 8	5.5		body mass (VT:0001259)	body weight (CMO:0000012)	3	125814931	139636791	Rat
1331758	Bp207	Blood pressure QTL 207	2.848		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	3	110634702	155634702	Rat
1358888	Bp264	Blood pressure QTL 264	4.43		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	3	5675975	141509147	Rat
724532	Cm17	Cardiac mass QTL 17	2		heart mass (VT:0007028)	calculated heart weight (CMO:0000073)	3	116188400	161188400	Rat

Markers in Region

RH139042

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	3	116,357,595 - 116,357,833 (+)	MAPPER	mRatBN7.2
Rnor_6.0	3	121,655,724 - 121,655,961	NCBI	Rnor6.0
Rnor_5.0	3	128,358,809 - 128,359,046	UniSTS	Rnor5.0
RGSC_v3.4	3	116,730,164 - 116,730,401	UniSTS	RGSC3.4
Celera	3	115,182,983 - 115,183,220	UniSTS
RH 3.4 Map	3	998.2	UniSTS
Cytogenetic Map	3	q36	UniSTS

RH140641

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	3	116,358,088 - 116,358,286 (+)	MAPPER	mRatBN7.2
Rnor_6.0	3	121,656,217 - 121,656,414	NCBI	Rnor6.0
Rnor_5.0	3	128,358,356 - 128,358,553	UniSTS	Rnor5.0
RGSC_v3.4	3	116,730,657 - 116,730,854	UniSTS	RGSC3.4
Celera	3	115,183,476 - 115,183,673	UniSTS
RH 3.4 Map	3	997.9	UniSTS
Cytogenetic Map	3	q36	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
16	12	67	163	91	90	59	92	59	6	356	192	11	142	81	92	31	17	17

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_031773	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC121664	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AF025424	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473949	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000003	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000024882 ⟹ ENSRNOP00000024882

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	3	136,787,107 - 136,811,607 (+)	Ensembl
mRatBN7.2 Ensembl	3	116,333,889 - 116,358,379 (+)	Ensembl
Rnor_6.0 Ensembl	3	121,632,043 - 121,656,506 (+)	Ensembl

RefSeq Acc Id:

NM_031773 ⟹ NP_113961

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	3	136,787,130 - 136,811,608 (+)	NCBI
mRatBN7.2	3	116,333,910 - 116,358,385 (+)	NCBI
Rnor_6.0	3	121,632,043 - 121,656,506 (+)	NCBI
Rnor_5.0	3	128,358,264 - 128,382,727 (-)	NCBI
RGSC_v3.4	3	116,706,483 - 116,730,946 (+)	RGD
Celera	3	115,159,305 - 115,183,765 (+)	RGD

Sequence:

show sequence

TGAATTGGTCCACGAGTGGAGTCGTAGCTCCGGTTTCCCGTCCGGGGCTCGCAGAAGCATGGAT
GTCGACAGCCGGTGGCGGAACCTGCCCAGCGGGCCCAGCCTAAAGCATTTAACCGACCCCTCGT
ACGCGGTTCCTCCGGAGCAGCAAAAGGCGGCGTTGCAGGACCTGACGCGGGCGCACGTGGACTC
CTTCAACTACGCAGTGCTGGAGGGGCTGAGCCACGCGGTGCAGGCCATACCTCCCTTCGAATTT
GCTTTCAAAGATGAGCGCATATCTCTTACTATTGTGGACGCTGCCATCAGTCCACCGGCAGTGC
CCAAAGGGACCATCTGCAAAGAGCTCAACATTTATCCAGCTGAGTGCCGTGGCCGGAGGAGCAC
GTACCGAGGGAAGCTGACGGCTGATATCAGCTGGGCCGTGAATGGAGTCCCCAAAGGCATCATT
AAACAATTTCTTGGCWATGTTCCCATCATGGTGAAGTCCAAGCTTTGCAACTTATACAACCTTC
CTCCTCAAGTCCTCATTGAGCACCACGAGGAGGCAGAGGAAATGGGCGGTTATTTTATAATCAA
CGGCATTGAGAAAGTCATCCGCATGTTGATTATGCCTCGGAGAAATTTTCCCATCGCAATGATA
AGACCGAAATGGAAAAGCAGAGGGCTCGGCTACACTCAGTTCGGGGTTTCCATTCACTGTGTGA
GAGAGGAGCACTCTGCTGTCAATATGAACCTTCACTATGTGGAGAACGGCACGGTCATGTTAAA
CTTTATTTACCGCAAAGAGCTGTTTTTCCTTCCTTTGGGATTTGCACTTAAGGCACTTGTGAGC
TTTTCTGACTATCAGATTTTCCAGGAGCTCATCAAAGGCAAAGAGGAGGACTCTTTCTTTAAGA
ATTCTGTTTCTCAGATGCTGAGGATTGTAATGGAGGAGGGTTGTCACACACAGAAGCAGGTCCT
CGACTATCTGGGCGAACGCTTCAGAGTAAAGCTCAGTCTTCCCGATTGGTACCCTAATGCGGAA
GCTGCCGAGTTCCTGTTTAACCAGTGTATCTGCATCCACTTGAAATCCAACACTGACAAGTTTT
ACCTGCTCTGTCTCATGACCCGGAAGCTCTTTGCTTTAGCCAGAGGAGAGTGCATGGAGGACAA
TCCTGACAGTTTAGTGAATCAAGAAGTCCTTACCCCTGGGCAGCTCTTCCTGATGTTTCTGAAG
GAAAAGATGGAGAATTGGCTACTGTCTATTAAAATAGCTTTAGATAAAAGGGCTCAGAAGACCA
ATGTTTCCATAAACAATGAAAATTTGATGAAGATTTTTAGTATGGGAACAGAGCTAACAAGACC
ATTTGAATATCTTCTTGCTACTGGAAATCTGCGTTCTAAAACAGGTCTTGGCTTCATGCAGGAT
TCTGGCCTGTGTGTTGTGGCTGACAAGCTGAACTTCATTCGCTATCTCTCCCATTTCCGCTGTG
TGCACAGAGGGGCTGACTTTGCCAAGATGAGGACCACCACCGTGCGCAAGCTGCTGCCAGAATC
CTGGGGCTTCCTCTGCCCTGTGCACACCCCAGACGGGGCACCGTGTGGGCTGCTGAACCACCTG
ACTGCTGTGTGTGAGGTTGTTACCAAGTTTGTGTACACAGCATCTATTCCAGCCTTGCTCTGTG
GCTTAGGAGTCACTCCTGTTGATGCAGCACCATGTCGACCGTATAGTGACTGCTACCCTGTCCT
GCTGGATGGCGTCATGGTGGGCTGGGTGGATAAGGAGCTGGCTCCTGAAGTGGCAGACACTCTC
CGTCGATTTAAGGTGTTGAGAGAAAGGAGATGTTCCTCCCTGGATGGAGGTGGCCCTGATTCCC
ATGACAGGAAAGCCAAGCCTGTACCCAGGGCTGTTCCTCTTCACCACTCCCTGCAGGCTGGTGA
GGCCTGTGCAGAACCTGGAGCTGGGCAAAGAAGAGCTCGTTGGAACTATGGAGCAGCTCTTCAT
GAACATTGCCATCTTCGAGGACGAGGTTTTTGGTGGAGTTTCCACACACCAGGAGCTCTTCCCT
CACAGCCTGCTGAGGTGATCGCCAACTTCATCCCCTTCTCTGATCACAACCAGAGTCCTCGGAA
CATGTACCAGTGCCAGATGGGTAAGCAGACCATGGGCTTCCCGCTGCTCACCTACCAAGACCGA
TCAGATAATAAACTCTATCGTCTCCAGACACCCCAGAGCCCTCTAGTGAGACCGTGCATGTATG
ATCATTATGACATGGACAACTATCCCATCGGGACAAACGCCATTGTGGCTGTGATCTCCTACAC
TGGCTATGATATGGAGGACGCCATGATTGTAAACAAGGCCTCCTGGGAACGAGGCTTTGCTCAT
GGAAGTGTCTACAAGTCTGAGTTCATAGACCTCTCTGAGAAATTTAAGCAAGGGGATGATAGTC
TGGTATTTGGGGTCAAACCTGGTGACCCACGGGTTATGCAGAAGCTGGACAATGATGGCTTGCC
ATTCATAGGAGCAAAGCTGGAGTTTGGTGATCCTTACTACGGCTACCTAAACCTTAACACCGGA
GAAGGCTTCGTGGTTTACTATAAGAGTAAAGAAAACTGTGTTGTGGACAACATCAAAGTGTGCA
GTAATGACACAGGAAGTGGGAAGTTCAAGTGCGTCTGCGTCACCGTCCGAGTCCCCCGGAACCC
AACTATTGGAGATAAGTTTGCCAGCCGTCACGGACAGAAGGGCATTTTGAGCAGATTGTGGCCA
GCTGAGGACATGCCTTTCACAGAGAGTGGGATGATGCCGGACATTCTGTTTAATCCTCATGGGT
TTCCCTCCCGTATGACCATAGGTATGTTAATCGAGAGTATGGCTGGGAAGTCAGCAGCTTTGCA
TGGTCTCTGCCATGATGCTACACCCTTCATCTTCTCCGAGGAGAACTCTGCCCTAGAGTACTTT
GGTGAGATGTTAAAGGCTGCCGGCTACAACTTCTATGGCACGGAGAGATTGTACAGCGGCATCA
GCGGGATGGAGCTGGAGGCTGACATTTTCATTGGTGTGGTTTATTACCAGCGCCTACGACACAT
GGTGTCAGACAAATTTCAAGTCAGAACAACTGGAGCCAGGGACAAAGTCACCAACCAGCCCATT
GGAGGCAGGAACGTCCAGGGTGGGATCCGATTTGGGGAGATGGAGCGGGATGCTCTGTTGGCGC
ACGGCACATCTTTCCTTCTGCATGACCGCCTCTTCAACTGCTCCGACCGCTCTGTGGCCCACGT
ATGCGTGAAGTGTGGCAGTTTGCTTTCTCCGCTGCTCGAGAAGCCTCCCCCATCTTGGTCTGCG
ATGCGTAACAGAAAATACAACTGCACCGTCTGCGGCCGCAGTGACTCCATCGACACTGTCTCTG
TGCCGTATGTTTTCCGGTACTTTGTAGCTGAGCTGGCTGCCATGAACATCAAAGTGAAACTGGA
CGTCATTTAACTTGATCACGGCCATCTGCGCTAGGAGAAGAGAACAAAAGGTGTCTTTAATCCA
GTGAGGATACTATGGGTTTGCTCTGGGTCTATATAAGAATTTCAGTACAGAAATGTCTCAGTAA
CCTACTGAAGTTGGTTTTGGTACATTCATTTTTAAAAAAAAATTATGTGCCTTCTTTAAAAAAT
GACTTAATTGATAATAGGTCATACAGGGCCCTTCTGGGCCCAGGTTCACTCGCTGTTCCCTGCT
TTGAGTAGTAGAGTGTGTCCGCCGTCTAGAGCAGGGCAGTACAATAAACAGAAAATG

hide sequence

Protein Sequences


Protein RefSeqs	NP_113961	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAB94600	(Get FASTA)	NCBI Sequence Viewer
	EDL80148	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000024882
GenBank Protein	O54888	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

NP_113961 ⟸ NM_031773

- UniProtKB:

O54888 (UniProtKB/Swiss-Prot), F1LM57 (UniProtKB/TrEMBL), A6HQ47 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MDVDSRWRNLPSGPSLKHLTDPSYAVPPEQQKAALQDLTRAHVDSFNYAVLEGLSHAVQAIPPF
EFAFKDERISLTIVDAAISPPAVPKGTICKELNIYPAECRGRRSTYRGKLTADISWAVNGVPKG
IIKQFLGXVPIMVKSKLCNLYNLPPQVLIEHHEEAEEMGGYFIINGIEKVIRMLIMPRRNFPIA
MIRPKWKSRGLGYTQFGVSIHCVREEHSAVNMNLHYVENGTVMLNFIYRKELFFLPLGFALKAL
VSFSDYQIFQELIKGKEEDSFFKNSVSQMLRIVMEEGCHTQKQVLDYLGERFRVKLSLPDWYPN
AEAAEFLFNQCICIHLKSNTDKFYLLCLMTRKLFALARGECMEDNPDSLVNQEVLTPGQLFLMF
LKEKMENWLLSIKIALDKRAQKTNVSINNENLMKIFSMGTELTRPFEYLLATGNLRSKTGLGFM
QDSGLCVVADKLNFIRYLSHFRCVHRGADFAKMRTTTVRKLLPESWGFLCPVHTPDGAPCGLLN
HLTAVCEVVTKFVYTASIPALLCGLGVTPVDAAPCRPYSDCYPVLLDGVMVGWVDKELAPEVAD
TLRRFKVLRERRCSSLDGGGPDSHDRKAKPVPRAVPLHHSLQAGEACAEPGAGQRRARWNYGAA
LHEHCHLRGRGFWWSFHTPGALPSQPAEVIANFIPFSDHNQSPRNMYQCQMGKQTMGFPLLTYQ
DRSDNKLYRLQTPQSPLVRPCMYDHYDMDNYPIGTNAIVAVISYTGYDMEDAMIVNKASWERGF
AHGSVYKSEFIDLSEKFKQGDDSLVFGVKPGDPRVMQKLDNDGLPFIGAKLEFGDPYYGYLNLN
TGEGFVVYYKSKENCVVDNIKVCSNDTGSGKFKCVCVTVRVPRNPTIGDKFASRHGQKGILSRL
WPAEDMPFTESGMMPDILFNPHGFPSRMTIGMLIESMAGKSAALHGLCHDATPFIFSEENSALE
YFGEMLKAAGYNFYGTERLYSGISGMELEADIFIGVVYYQRLRHMVSDKFQVRTTGARDKVTNQ
PIGGRNVQGGIRFGEMERDALLAHGTSFLLHDRLFNCSDRSVAHVCVKCGSLLSPLLEKPPPSW
SAMRNRKYNCTVCGRSDSIDTVSVPYVFRYFVAELAAMNIKVKLDVI

hide sequence

Ensembl Acc Id:

ENSRNOP00000024882 ⟸ ENSRNOT00000024882

Protein Domains

DNA-directed RNA polymerase I subunit RPA2 DNA-directed RNA polymerase subunit 2 hybrid- RNA polymerase beta subunit protrusion RNA polymerase Rpb2

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13692419

Promoter ID:

EPDNEW_R2944

Type:

multiple initiation site

Name:

Polr1b_1

Description:

RNA polymerase I subunit B

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	3	121,632,035 - 121,632,095	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:620822	AgrOrtholog
BioCyc Gene	G2FUF-47926	BioCyc
Ensembl Genes	ENSRNOG00000018349	Ensembl, ENTREZGENE
Ensembl Transcript	ENSRNOT00000024882	ENTREZGENE
Gene3D-CATH	2.40.270.10	UniProtKB/Swiss-Prot
	2.40.50.150	UniProtKB/Swiss-Prot
	3.90.1070.20	UniProtKB/Swiss-Prot
	3.90.1100.10	UniProtKB/Swiss-Prot
	3.90.1110.10	UniProtKB/Swiss-Prot
	RNA polymerase alpha subunit dimerisation domain	UniProtKB/Swiss-Prot
InterPro	DNA-dir_RNA_pol_su2	UniProtKB/Swiss-Prot
	DNA-dir_RNAP_su2_dom	UniProtKB/Swiss-Prot
	DNA-dir_RNAP_su2_hyb_sf	UniProtKB/Swiss-Prot
	RNA_pol_bsu_CS	UniProtKB/Swiss-Prot
	RNA_pol_bsu_protrusion	UniProtKB/Swiss-Prot
	RNA_pol_Rpb2_2	UniProtKB/Swiss-Prot
	RNA_pol_Rpb2_2_sf	UniProtKB/Swiss-Prot
	RNA_pol_Rpb2_3	UniProtKB/Swiss-Prot
	RNA_pol_Rpb2_7	UniProtKB/Swiss-Prot
	RNA_pol_RPB2_OB-fold	UniProtKB/Swiss-Prot
KEGG Report	rno:83582	UniProtKB/Swiss-Prot
NCBI Gene	83582	ENTREZGENE
PANTHER	PTHR20856	UniProtKB/Swiss-Prot
Pfam	RNA_pol_Rpb2_1	UniProtKB/Swiss-Prot
	RNA_pol_Rpb2_2	UniProtKB/Swiss-Prot
	RNA_pol_Rpb2_3	UniProtKB/Swiss-Prot
	RNA_pol_Rpb2_6	UniProtKB/Swiss-Prot
	RNA_pol_Rpb2_7	UniProtKB/Swiss-Prot
PhenoGen	Polr1b	PhenoGen
PROSITE	RNA_POL_BETA	UniProtKB/Swiss-Prot
RatGTEx	ENSRNOG00000018349	RatGTEx
Superfamily-SCOP	beta and beta-prime subunits of DNA dependent RNA-polymerase	UniProtKB/Swiss-Prot
UniProt	A6HQ47	ENTREZGENE, UniProtKB/TrEMBL
	F1LM57	ENTREZGENE, UniProtKB/TrEMBL
	O54888	ENTREZGENE, UniProtKB/Swiss-Prot

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2016-07-21	Polr1b	RNA polymerase I subunit B	Polr1b	polymerase (RNA) I subunit B	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2016-03-09	Polr1b	polymerase (RNA) I subunit B	Polr1b	polymerase (RNA) I polypeptide B	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-11-06	Polr1b	polymerase (RNA) I polypeptide B	Rpo1-2	RNA polymerase 1-2	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2004-02-11	Ptpn23	RNA polymerase 1-2	Rpo1-2	RNA polymerase I (127 kDa subunit)	Name updated to reflect Human and Mouse nomenclature	625702	APPROVED
2002-08-07	Rpo1-2	RNA polymerase I (127 kDa subunit)			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - OMIM

RGD Manual Annotations

Imported Annotations - KEGG (archival)

Send us a Message

Imported Disease Annotations - ClinVar

Imported Disease Annotations - OMIM

RGD Manual Annotations

Imported Annotations - KEGG (archival)