Symbol:
Polr1b
Name:
RNA polymerase I subunit B
RGD ID:
620822
Description:
Contributes to DNA-directed RNA polymerase activity. Involved in rRNA transcription. Part of RNA polymerase I complex. Human ortholog(s) of this gene implicated in Treacher Collins syndrome 4. Orthologous to human POLR1B (RNA polymerase I subunit B); PARTICIPATES IN RNA polymerase I transcription pathway; purine metabolic pathway; pyrimidine metabolic pathway; INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene.
Type:
protein-coding
RefSeq Status:
VALIDATED
Previously known as:
A127; DNA-directed RNA polymerase I subunit RPA2; polymerase (RNA) I polypeptide B; polymerase (RNA) I subunit B; RNA polymerase 1-2; RNA polymerase I (127 kDa subunit); RNA polymerase I polypeptide B; RNA polymerase I subunit 2; RPA135; RPA2; Rpo1-2
RGD Orthologs
Alliance Orthologs
More Info
more info ...
More Info
Latest Assembly:
GRCr8 - GRCr8 Assembly
Position:
Rat Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCr8 3 136,787,130 - 136,811,608 (+) NCBI GRCr8 mRatBN7.2 3 116,333,910 - 116,358,385 (+) NCBI mRatBN7.2 mRatBN7.2 mRatBN7.2 Ensembl 3 116,333,889 - 116,358,379 (+) Ensembl mRatBN7.2 Ensembl UTH_Rnor_SHR_Utx 3 120,231,013 - 120,255,438 (+) NCBI Rnor_SHR UTH_Rnor_SHR_Utx UTH_Rnor_SHRSP_BbbUtx_1.0 3 128,826,598 - 128,851,016 (+) NCBI Rnor_SHRSP UTH_Rnor_SHRSP_BbbUtx_1.0 UTH_Rnor_WKY_Bbb_1.0 3 126,487,078 - 126,511,500 (+) NCBI Rnor_WKY UTH_Rnor_WKY_Bbb_1.0 Rnor_6.0 3 121,632,043 - 121,656,506 (+) NCBI Rnor6.0 Rnor_6.0 rn6 Rnor6.0 Rnor_6.0 Ensembl 3 121,632,043 - 121,656,506 (+) Ensembl Rnor6.0 rn6 Rnor6.0 Rnor_5.0 3 128,358,264 - 128,382,727 (-) NCBI Rnor5.0 Rnor_5.0 rn5 Rnor5.0 RGSC_v3.4 3 116,706,483 - 116,730,946 (+) NCBI RGSC3.4 RGSC_v3.4 rn4 RGSC3.4 RGSC_v3.1 3 116,612,055 - 116,636,519 (+) NCBI Celera 3 115,159,305 - 115,183,765 (+) NCBI Celera Cytogenetic Map 3 q36 NCBI
JBrowse:
View Region in Genome Browser (JBrowse)
Model
Only show annotations with direct experimental evidence (0 objects hidden)
Polr1b Rat (+)-schisandrin B multiple interactions EXP 6480464 schizandrin B inhibits the reaction [Carbon Tetrachloride results in increased expression of POLR1B mRNA] CTD PMID:31150632 Polr1b Rat (-)-alpha-phellandrene decreases expression ISO RGD:1348858 6480464 alpha phellandrene results in decreased expression of POLR1B mRNA CTD PMID:25075043 Polr1b Rat 1,2-dimethylhydrazine increases expression ISO RGD:731265 6480464 1,2-Dimethylhydrazine results in increased expression of POLR1B mRNA CTD PMID:22206623 Polr1b Rat 17beta-estradiol increases expression ISO RGD:1348858 6480464 Estradiol results in increased expression of POLR1B mRNA CTD PMID:23019147|PMID:31614463 Polr1b Rat 2,3,7,8-tetrachlorodibenzodioxine increases expression EXP 6480464 Tetrachlorodibenzodioxin results in increased expression of POLR1B mRNA CTD PMID:32109520 Polr1b Rat 2,4-dinitrotoluene affects expression EXP 6480464 2,4-dinitrotoluene affects the expression of POLR1B mRNA CTD PMID:21346803 Polr1b Rat 4,4'-diaminodiphenylmethane increases expression ISO RGD:731265 6480464 4,4'-diaminodiphenylmethane results in increased expression of POLR1B mRNA CTD PMID:18648102 Polr1b Rat aflatoxin B1 increases methylation ISO RGD:1348858 6480464 Aflatoxin B1 results in increased methylation of POLR1B intron CTD PMID:30157460 Polr1b Rat all-trans-retinoic acid increases expression EXP 6480464 Tretinoin results in increased expression of POLR1B mRNA CTD PMID:20488242 Polr1b Rat all-trans-retinoic acid decreases expression ISO RGD:1348858 6480464 Tretinoin results in decreased expression of POLR1B mRNA CTD PMID:23724009|PMID:33167477 Polr1b Rat alpha-phellandrene decreases expression ISO RGD:1348858 6480464 alpha phellandrene results in decreased expression of POLR1B mRNA CTD PMID:25075043 Polr1b Rat ammonium chloride affects expression EXP 6480464 Ammonium Chloride affects the expression of POLR1B mRNA CTD PMID:16483693 Polr1b Rat amphetamine decreases expression EXP 6480464 Amphetamine results in decreased expression of POLR1B mRNA CTD PMID:30779732 Polr1b Rat antirheumatic drug decreases expression ISO RGD:1348858 6480464 Antirheumatic Agents results in decreased expression of POLR1B mRNA CTD PMID:24449571 Polr1b Rat arsane multiple interactions ISO RGD:1348858 6480464 [sodium arsenite results in increased abundance of Arsenic] which results in increased expression of POLR1B more ... CTD PMID:39836092 Polr1b Rat arsenic atom multiple interactions ISO RGD:1348858 6480464 [sodium arsenite results in increased abundance of Arsenic] which results in increased expression of POLR1B more ... CTD PMID:39836092 Polr1b Rat atrazine decreases expression ISO RGD:1348858 6480464 Atrazine results in decreased expression of POLR1B mRNA CTD PMID:22378314 Polr1b Rat benzo[a]pyrene multiple interactions ISO RGD:731265 6480464 Benzo(a)pyrene promotes the reaction [AHR protein binds to POLR1B promoter] CTD PMID:19654925 Polr1b Rat benzo[a]pyrene decreases methylation ISO RGD:1348858 6480464 Benzo(a)pyrene results in decreased methylation of POLR1B promoter CTD PMID:27901495 Polr1b Rat benzo[a]pyrene increases methylation ISO RGD:1348858 6480464 Benzo(a)pyrene results in increased methylation of POLR1B 3' UTR CTD PMID:27901495 Polr1b Rat benzo[a]pyrene diol epoxide I decreases expression ISO RGD:1348858 6480464 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in decreased expression of POLR1B mRNA CTD PMID:19150397 Polr1b Rat beta-hexachlorocyclohexane decreases expression ISO RGD:731265 6480464 beta-hexachlorocyclohexane results in decreased expression of POLR1B mRNA CTD PMID:25270620 Polr1b Rat bis(2-chloroethyl) sulfide increases expression ISO RGD:731265 6480464 Mustard Gas results in increased expression of POLR1B mRNA CTD PMID:15674844 Polr1b Rat bisphenol A decreases expression ISO RGD:731265 6480464 bisphenol A results in decreased expression of POLR1B mRNA CTD PMID:26063408 Polr1b Rat bisphenol A increases methylation EXP 6480464 bisphenol A results in increased methylation of POLR1B gene CTD PMID:28505145 Polr1b Rat bisphenol A decreases methylation ISO RGD:731265 6480464 bisphenol A results in decreased methylation of POLR1B promoter CTD PMID:27312807 Polr1b Rat bisphenol A increases expression EXP 6480464 bisphenol A results in increased expression of POLR1B mRNA CTD PMID:25181051|PMID:30816183|PMID:34947998 Polr1b Rat bisphenol F decreases expression ISO RGD:731265 6480464 bisphenol F results in decreased expression of POLR1B mRNA CTD PMID:38685157 Polr1b Rat cadmium dichloride decreases expression ISO RGD:731265 6480464 Cadmium Chloride results in decreased expression of POLR1B mRNA CTD PMID:20883709 Polr1b Rat cadmium dichloride decreases expression ISO RGD:1348858 6480464 Cadmium Chloride results in decreased expression of POLR1B mRNA CTD PMID:38568856 Polr1b Rat carbon nanotube increases expression ISO RGD:731265 6480464 Nanotubes, Carbon results in increased expression of POLR1B mRNA CTD PMID:25554681 Polr1b Rat chlorpyrifos decreases expression ISO RGD:731265 6480464 Chlorpyrifos results in decreased expression of POLR1B mRNA CTD PMID:37019170 Polr1b Rat chromium(6+) affects expression ISO RGD:731265 6480464 chromium hexavalent ion affects the expression of POLR1B mRNA CTD PMID:28472532 Polr1b Rat copper(II) sulfate decreases expression ISO RGD:1348858 6480464 Copper Sulfate results in decreased expression of POLR1B mRNA CTD PMID:19549813 Polr1b Rat cordycepin decreases expression ISO RGD:731265 6480464 cordycepin results in decreased expression of POLR1B mRNA CTD PMID:32042022 Polr1b Rat coumestrol increases expression ISO RGD:1348858 6480464 Coumestrol results in increased expression of POLR1B mRNA CTD PMID:19167446 Polr1b Rat DDE increases expression ISO RGD:1348858 6480464 Dichlorodiphenyl Dichloroethylene results in increased expression of POLR1B mRNA CTD PMID:38568856 Polr1b Rat Dibutyl phosphate affects expression ISO RGD:1348858 6480464 di-n-butylphosphoric acid affects the expression of POLR1B mRNA CTD PMID:37042841 Polr1b Rat dioxygen multiple interactions ISO RGD:731265 6480464 [NFE2L2 protein affects the susceptibility to Oxygen] which affects the expression of POLR1B mRNA CTD PMID:30529165 Polr1b Rat doxorubicin decreases expression ISO RGD:1348858 6480464 Doxorubicin results in decreased expression of POLR1B mRNA CTD PMID:29803840 Polr1b Rat ethyl methanesulfonate decreases expression ISO RGD:1348858 6480464 Ethyl Methanesulfonate results in decreased expression of POLR1B mRNA CTD PMID:23649840 Polr1b Rat flavonoids increases expression EXP 6480464 Flavonoids results in increased expression of POLR1B mRNA CTD PMID:18035473 Polr1b Rat flutamide increases expression EXP 6480464 Flutamide results in increased expression of POLR1B mRNA CTD PMID:24136188 Polr1b Rat flutamide decreases expression EXP 6480464 Flutamide results in decreased expression of POLR1B mRNA CTD PMID:24793618 Polr1b Rat formaldehyde decreases expression ISO RGD:1348858 6480464 Formaldehyde results in decreased expression of POLR1B mRNA CTD PMID:20655997 Polr1b Rat gentamycin decreases expression EXP 6480464 Gentamicins results in decreased expression of POLR1B mRNA CTD PMID:33387578 Polr1b Rat hydrogen peroxide affects expression ISO RGD:1348858 6480464 Hydrogen Peroxide affects the expression of POLR1B mRNA CTD PMID:20044591 Polr1b Rat hydrogen peroxide multiple interactions ISO RGD:1348858 6480464 [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of POLR1B protein CTD PMID:18951874 Polr1b Rat hydroquinone decreases expression ISO RGD:1348858 6480464 hydroquinone results in decreased expression of POLR1B mRNA CTD PMID:31256213 Polr1b Rat Indeno[1,2,3-cd]pyrene decreases expression ISO RGD:731265 6480464 indeno(1,2,3-cd)pyrene results in decreased expression of POLR1B mRNA CTD PMID:26377693 Polr1b Rat ivermectin decreases expression ISO RGD:1348858 6480464 Ivermectin results in decreased expression of POLR1B protein CTD PMID:32959892 Polr1b Rat lead(0) increases expression ISO RGD:1348858 6480464 Lead results in increased expression of POLR1B mRNA CTD PMID:19921347 Polr1b Rat maneb multiple interactions ISO RGD:731265 6480464 [Maneb co-treated with Paraquat] results in decreased expression of POLR1B mRNA CTD PMID:36117858 Polr1b Rat methotrexate affects expression ISO RGD:731265 6480464 Methotrexate affects the expression of POLR1B mRNA CTD PMID:18502557 Polr1b Rat methotrexate decreases expression ISO RGD:1348858 6480464 Methotrexate results in decreased expression of POLR1B mRNA CTD PMID:24449571 Polr1b Rat methyl methanesulfonate decreases expression ISO RGD:1348858 6480464 Methyl Methanesulfonate results in decreased expression of POLR1B mRNA CTD PMID:23649840 Polr1b Rat methylmercury chloride increases expression ISO RGD:1348858 6480464 methylmercuric chloride results in increased expression of POLR1B mRNA CTD PMID:28001369 Polr1b Rat N-nitrosodiethylamine increases expression EXP 6480464 Diethylnitrosamine results in increased expression of POLR1B mRNA CTD PMID:20360939 Polr1b Rat nickel atom decreases expression ISO RGD:1348858 6480464 Nickel results in decreased expression of POLR1B mRNA CTD PMID:23195993 Polr1b Rat nitroglycerin increases expression EXP 6480464 Nitroglycerin results in increased expression of POLR1B mRNA CTD PMID:12102619 Polr1b Rat paracetamol decreases expression ISO RGD:1348858 6480464 Acetaminophen results in decreased expression of POLR1B mRNA CTD PMID:21420995 Polr1b Rat paraquat increases expression EXP 6480464 Paraquat results in increased expression of POLR1B mRNA CTD PMID:32680482 Polr1b Rat paraquat multiple interactions ISO RGD:731265 6480464 [Maneb co-treated with Paraquat] results in decreased expression of POLR1B mRNA CTD PMID:36117858 Polr1b Rat perfluorooctanoic acid increases expression EXP 6480464 perfluorooctanoic acid results in increased expression of POLR1B mRNA CTD PMID:19162173 Polr1b Rat perfluorooctanoic acid decreases expression ISO RGD:1348858 6480464 perfluorooctanoic acid results in decreased expression of POLR1B mRNA CTD PMID:23978341 Polr1b Rat phenobarbital increases expression EXP 6480464 Phenobarbital results in increased expression of POLR1B mRNA CTD PMID:12832660 Polr1b Rat pirinixic acid multiple interactions ISO RGD:731265 6480464 [pirinixic acid binds to and results in increased activity of PPARA protein] which results in more ... CTD PMID:19710929 Polr1b Rat pirinixic acid increases expression ISO RGD:731265 6480464 pirinixic acid results in increased expression of POLR1B mRNA CTD PMID:18301758 Polr1b Rat pregnenolone 16alpha-carbonitrile increases expression ISO RGD:731265 6480464 Pregnenolone Carbonitrile results in increased expression of POLR1B mRNA CTD PMID:28903501 Polr1b Rat progesterone decreases expression ISO RGD:1348858 6480464 Progesterone results in decreased expression of POLR1B mRNA CTD PMID:18037150 Polr1b Rat silicon dioxide increases expression ISO RGD:1348858 6480464 Silicon Dioxide analog results in increased expression of POLR1B mRNA CTD PMID:25895662 Polr1b Rat sodium arsenite decreases expression ISO RGD:731265 6480464 sodium arsenite results in decreased expression of POLR1B mRNA CTD PMID:20883709 Polr1b Rat sodium arsenite multiple interactions ISO RGD:1348858 6480464 [sodium arsenite results in increased abundance of Arsenic] which results in increased expression of POLR1B more ... CTD PMID:39836092 Polr1b Rat sodium arsenite decreases expression ISO RGD:1348858 6480464 sodium arsenite results in decreased expression of POLR1B mRNA CTD PMID:38568856 Polr1b Rat sodium dichromate increases expression EXP 6480464 sodium bichromate results in increased expression of POLR1B mRNA CTD PMID:25993096 Polr1b Rat sunitinib decreases expression ISO RGD:1348858 6480464 Sunitinib results in decreased expression of POLR1B mRNA CTD PMID:31533062 Polr1b Rat testosterone decreases expression ISO RGD:1348858 6480464 Testosterone results in decreased expression of POLR1B mRNA CTD PMID:33359661 Polr1b Rat tetrachloromethane increases expression EXP 6480464 Carbon Tetrachloride results in increased expression of POLR1B mRNA CTD PMID:31150632 Polr1b Rat tetrachloromethane multiple interactions EXP 6480464 schizandrin B inhibits the reaction [Carbon Tetrachloride results in increased expression of POLR1B mRNA] CTD PMID:31150632 Polr1b Rat tetraphene decreases expression ISO RGD:731265 6480464 benz(a)anthracene results in decreased expression of POLR1B mRNA CTD PMID:26377693 Polr1b Rat theophylline multiple interactions ISO RGD:1348858 6480464 [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of POLR1B protein CTD PMID:18951874 Polr1b Rat thioacetamide decreases expression EXP 6480464 Thioacetamide results in decreased expression of POLR1B mRNA CTD PMID:16297948 Polr1b Rat thioacetamide increases expression EXP 6480464 Thioacetamide results in increased expression of POLR1B mRNA CTD PMID:23411599|PMID:34492290 Polr1b Rat thiram decreases expression ISO RGD:1348858 6480464 Thiram results in decreased expression of POLR1B mRNA CTD PMID:38568856 Polr1b Rat titanium dioxide increases expression ISO RGD:731265 6480464 titanium dioxide results in increased expression of POLR1B mRNA CTD PMID:23131501 Polr1b Rat titanium dioxide increases methylation ISO RGD:731265 6480464 titanium dioxide results in increased methylation of POLR1B gene CTD PMID:35295148 Polr1b Rat titanium dioxide decreases methylation ISO RGD:731265 6480464 titanium dioxide results in decreased methylation of POLR1B gene CTD PMID:35295148 Polr1b Rat toluene 2,4-diisocyanate increases expression ISO RGD:731265 6480464 Toluene 2,4-Diisocyanate results in increased expression of POLR1B mRNA CTD PMID:21404309 Polr1b Rat Tributyltin oxide decreases expression ISO RGD:731265 6480464 bis(tri-n-butyltin)oxide results in decreased expression of POLR1B mRNA CTD PMID:25270620 Polr1b Rat trimellitic anhydride increases expression ISO RGD:731265 6480464 trimellitic anhydride results in increased expression of POLR1B mRNA CTD PMID:19042947 Polr1b Rat triphenyl phosphate affects expression ISO RGD:1348858 6480464 triphenyl phosphate affects the expression of POLR1B mRNA CTD PMID:37042841 Polr1b Rat urethane decreases expression ISO RGD:1348858 6480464 Urethane results in decreased expression of POLR1B mRNA CTD PMID:28818685 Polr1b Rat valproic acid affects expression ISO RGD:731265 6480464 Valproic Acid affects the expression of POLR1B mRNA CTD PMID:17292431 Polr1b Rat valproic acid increases expression ISO RGD:1348858 6480464 Valproic Acid results in increased expression of POLR1B mRNA CTD PMID:23179753|PMID:29154799 Polr1b Rat vinclozolin affects expression EXP 6480464 vinclozolin affects the expression of POLR1B mRNA CTD PMID:23034163 Polr1b Rat vincristine decreases expression ISO RGD:1348858 6480464 Vincristine results in decreased expression of POLR1B mRNA CTD PMID:23649840
Imported Annotations - KEGG (archival)
(+)-schisandrin B (EXP) (-)-alpha-phellandrene (ISO) 1,2-dimethylhydrazine (ISO) 17beta-estradiol (ISO) 2,3,7,8-tetrachlorodibenzodioxine (EXP) 2,4-dinitrotoluene (EXP) 4,4'-diaminodiphenylmethane (ISO) aflatoxin B1 (ISO) all-trans-retinoic acid (EXP,ISO) alpha-phellandrene (ISO) ammonium chloride (EXP) amphetamine (EXP) antirheumatic drug (ISO) arsane (ISO) arsenic atom (ISO) atrazine (ISO) benzo[a]pyrene (ISO) benzo[a]pyrene diol epoxide I (ISO) beta-hexachlorocyclohexane (ISO) bis(2-chloroethyl) sulfide (ISO) bisphenol A (EXP,ISO) bisphenol F (ISO) cadmium dichloride (ISO) carbon nanotube (ISO) chlorpyrifos (ISO) chromium(6+) (ISO) copper(II) sulfate (ISO) cordycepin (ISO) coumestrol (ISO) DDE (ISO) Dibutyl phosphate (ISO) dioxygen (ISO) doxorubicin (ISO) ethyl methanesulfonate (ISO) flavonoids (EXP) flutamide (EXP) formaldehyde (ISO) gentamycin (EXP) hydrogen peroxide (ISO) hydroquinone (ISO) Indeno[1,2,3-cd]pyrene (ISO) ivermectin (ISO) lead(0) (ISO) maneb (ISO) methotrexate (ISO) methyl methanesulfonate (ISO) methylmercury chloride (ISO) N-nitrosodiethylamine (EXP) nickel atom (ISO) nitroglycerin (EXP) paracetamol (ISO) paraquat (EXP,ISO) perfluorooctanoic acid (EXP,ISO) phenobarbital (EXP) pirinixic acid (ISO) pregnenolone 16alpha-carbonitrile (ISO) progesterone (ISO) silicon dioxide (ISO) sodium arsenite (ISO) sodium dichromate (EXP) sunitinib (ISO) testosterone (ISO) tetrachloromethane (EXP) tetraphene (ISO) theophylline (ISO) thioacetamide (EXP) thiram (ISO) titanium dioxide (ISO) toluene 2,4-diisocyanate (ISO) Tributyltin oxide (ISO) trimellitic anhydride (ISO) triphenyl phosphate (ISO) urethane (ISO) valproic acid (ISO) vinclozolin (EXP) vincristine (ISO)
1.
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.
Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.
Affinity purification of mammalian RNA polymerase I. Identification of an associated kinase.
Hannan RD, etal., J Biol Chem. 1998 Jan 9;273(2):1257-67.
3.
KEGG: Kyoto Encyclopedia of Genes and Genomes
KEGG
4.
Rat ISS GO annotations from MGI mouse gene data--August 2006
MGD data from the GO Consortium
5.
Electronic Transfer of LocusLink and RefSeq Data
NCBI rat LocusLink and RefSeq merged data July 26, 2002
6.
KEGG Annotation Import Pipeline
Pipeline to import KEGG annotations from KEGG into RGD
7.
GOA pipeline
RGD automated data pipeline
8.
ClinVar Automated Import and Annotation Pipeline
RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
9.
Data Import for Chemical-Gene Interactions
RGD automated import pipeline for gene-chemical interactions
10.
Comprehensive gene review and curation
RGD comprehensive gene curation
11.
RNA polymerase I activity is regulated at multiple steps in the transcription cycle: recent insights into factors that influence transcription elongation.
Schneider DA Gene. 2012 Feb 10;493(2):176-84. doi: 10.1016/j.gene.2011.08.006. Epub 2011 Aug 26.
12.
Molecular cloning of RPA2, the gene encoding the second largest subunit of mouse RNA polymerase I.
Seither P and Grummt I, Genomics 1996 Oct 1;37(1):135-9.
13.
Conservation between the RNA polymerase I, II, and III transcription initiation machineries.
Vannini A and Cramer P, Mol Cell. 2012 Feb 24;45(4):439-46. doi: 10.1016/j.molcel.2012.01.023.
Polr1b Rat Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCr8 3 136,787,130 - 136,811,608 (+) NCBI GRCr8 mRatBN7.2 3 116,333,910 - 116,358,385 (+) NCBI mRatBN7.2 mRatBN7.2 mRatBN7.2 Ensembl 3 116,333,889 - 116,358,379 (+) Ensembl mRatBN7.2 Ensembl UTH_Rnor_SHR_Utx 3 120,231,013 - 120,255,438 (+) NCBI Rnor_SHR UTH_Rnor_SHR_Utx UTH_Rnor_SHRSP_BbbUtx_1.0 3 128,826,598 - 128,851,016 (+) NCBI Rnor_SHRSP UTH_Rnor_SHRSP_BbbUtx_1.0 UTH_Rnor_WKY_Bbb_1.0 3 126,487,078 - 126,511,500 (+) NCBI Rnor_WKY UTH_Rnor_WKY_Bbb_1.0 Rnor_6.0 3 121,632,043 - 121,656,506 (+) NCBI Rnor6.0 Rnor_6.0 rn6 Rnor6.0 Rnor_6.0 Ensembl 3 121,632,043 - 121,656,506 (+) Ensembl Rnor6.0 rn6 Rnor6.0 Rnor_5.0 3 128,358,264 - 128,382,727 (-) NCBI Rnor5.0 Rnor_5.0 rn5 Rnor5.0 RGSC_v3.4 3 116,706,483 - 116,730,946 (+) NCBI RGSC3.4 RGSC_v3.4 rn4 RGSC3.4 RGSC_v3.1 3 116,612,055 - 116,636,519 (+) NCBI Celera 3 115,159,305 - 115,183,765 (+) NCBI Celera Cytogenetic Map 3 q36 NCBI
POLR1B Human Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCh38 2 112,542,036 - 112,579,818 (+) NCBI GRCh38 GRCh38 hg38 GRCh38 GRCh38.p14 Ensembl 2 112,541,915 - 112,579,818 (+) Ensembl GRCh38 hg38 GRCh38 GRCh37 2 113,299,613 - 113,337,395 (+) NCBI GRCh37 GRCh37 hg19 GRCh37 Build 36 2 113,016,084 - 113,051,879 (+) NCBI NCBI36 Build 36 hg18 NCBI36 Build 34 2 113,015,843 - 113,051,639 NCBI Celera 2 106,685,049 - 106,720,277 (+) NCBI Celera Cytogenetic Map 2 q14.1 NCBI HuRef 2 105,754,007 - 105,789,231 (+) NCBI HuRef CHM1_1 2 113,303,652 - 113,338,870 (+) NCBI CHM1_1 T2T-CHM13v2.0 2 112,968,686 - 113,006,450 (+) NCBI T2T-CHM13v2.0
Polr1b Mouse Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCm39 2 128,942,891 - 128,969,980 (+) NCBI GRCm39 GRCm39 mm39 GRCm39 Ensembl 2 128,942,915 - 128,968,514 (+) Ensembl GRCm39 Ensembl GRCm38 2 129,100,970 - 129,128,060 (+) NCBI GRCm38 GRCm38 mm10 GRCm38 GRCm38.p6 Ensembl 2 129,100,995 - 129,126,594 (+) Ensembl GRCm38 mm10 GRCm38 MGSCv37 2 128,926,732 - 128,952,331 (+) NCBI GRCm37 MGSCv37 mm9 NCBIm37 MGSCv36 2 128,792,479 - 128,818,036 (+) NCBI MGSCv36 mm8 Celera 2 130,328,366 - 130,353,838 (+) NCBI Celera Cytogenetic Map 2 F1 NCBI cM Map 2 62.68 NCBI
Polr1b Chinchilla Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl ChiLan1.0 Ensembl NW_004955470 1,714,156 - 1,737,820 (-) Ensembl ChiLan1.0 ChiLan1.0 NW_004955470 1,714,156 - 1,737,749 (-) NCBI ChiLan1.0 ChiLan1.0
POLR1B Bonobo Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl NHGRI_mPanPan1-v2 12 15,545,294 - 15,588,412 (-) NCBI NHGRI_mPanPan1-v2 NHGRI_mPanPan1 2A 15,548,058 - 15,584,608 (-) NCBI NHGRI_mPanPan1 Mhudiblu_PPA_v0 2A 89,478,133 - 89,516,559 (-) NCBI Mhudiblu_PPA_v0 Mhudiblu_PPA_v0 panPan3 PanPan1.1 2A 113,555,452 - 113,590,377 (+) NCBI panpan1.1 PanPan1.1 panPan2 PanPan1.1 Ensembl 2A 113,555,452 - 113,590,377 (+) Ensembl panpan1.1 panPan2
POLR1B Dog Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl CanFam3.1 17 36,774,472 - 36,798,900 (+) NCBI CanFam3.1 CanFam3.1 canFam3 CanFam3.1 CanFam3.1 Ensembl 17 36,774,541 - 36,797,525 (+) Ensembl CanFam3.1 canFam3 CanFam3.1 Dog10K_Boxer_Tasha 17 36,543,712 - 36,568,761 (+) NCBI Dog10K_Boxer_Tasha ROS_Cfam_1.0 17 37,550,047 - 37,575,002 (+) NCBI ROS_Cfam_1.0 ROS_Cfam_1.0 Ensembl 17 37,545,667 - 37,575,002 (+) Ensembl ROS_Cfam_1.0 Ensembl UMICH_Zoey_3.1 17 36,688,159 - 36,713,214 (+) NCBI UMICH_Zoey_3.1 UNSW_CanFamBas_1.0 17 36,742,224 - 36,767,072 (+) NCBI UNSW_CanFamBas_1.0 UU_Cfam_GSD_1.0 17 36,956,099 - 36,980,996 (+) NCBI UU_Cfam_GSD_1.0
Polr1b Squirrel Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl HiC_Itri_2 NW_024406292 82,139,613 - 82,161,453 (+) NCBI HiC_Itri_2 SpeTri2.0 Ensembl NW_004936783 1,034,054 - 1,056,384 (+) Ensembl SpeTri2.0 SpeTri2.0 Ensembl SpeTri2.0 NW_004936783 1,034,097 - 1,055,798 (+) NCBI SpeTri2.0 SpeTri2.0 SpeTri2.0
POLR1B Pig Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl Sscrofa11.1 Ensembl 3 43,950,002 - 43,975,683 (-) Ensembl Sscrofa11.1 susScr11 Sscrofa11.1 Sscrofa11.1 3 43,949,032 - 43,974,283 (-) NCBI Sscrofa11.1 Sscrofa11.1 susScr11 Sscrofa11.1 Sscrofa10.2 3 45,544,060 - 45,568,445 (-) NCBI Sscrofa10.2 Sscrofa10.2 susScr3
POLR1B Green Monkey Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl ChlSab1.1 14 15,549,963 - 15,585,947 (+) NCBI ChlSab1.1 ChlSab1.1 chlSab2 ChlSab1.1 Ensembl 14 15,550,254 - 15,584,521 (+) Ensembl ChlSab1.1 ChlSab1.1 Ensembl chlSab2 Vero_WHO_p1.0 NW_023666080 4,095,537 - 4,131,082 (-) NCBI Vero_WHO_p1.0 Vero_WHO_p1.0
Polr1b
.
Predicted Target Of
Count of predictions: 59 Count of miRNA genes: 47 Interacting mature miRNAs: 55 Transcripts: ENSRNOT00000024882 Prediction methods: Miranda, Rnahybrid, Targetscan Result types: miRGate_prediction
2312673 Scl63 Serum cholesterol level QTL 63 0.001 blood cholesterol amount (VT:0000180) serum total cholesterol level (CMO:0000363) 3 98535255 168026850 Rat 2301414 Kidm37 Kidney mass QTL 37 0.001 kidney mass (VT:0002707) both kidneys wet weight to body weight ratio (CMO:0000340) 3 70653097 121056321 Rat 2302373 Gluco39 Glucose level QTL 39 5.01 blood glucose amount (VT:0000188) blood glucose level area under curve (AUC) (CMO:0000350) 3 98535386 161695835 Rat 70216 Cm14 Cardiac mass QTL 14 2.1 heart mass (VT:0007028) heart wet weight (CMO:0000069) 3 31172320 163586636 Rat 2292591 Esta4 Estrogen-induced thymic atrophy QTL 4 thymus mass (VT:0004954) thymus wet weight (CMO:0000855) 3 47233211 147415807 Rat 1358362 Srcrt2 Stress Responsive Cort QTL 2 2.78 blood corticosterone amount (VT:0005345) plasma corticosterone level (CMO:0001173) 3 38192233 133483320 Rat 737818 Hcar12 Hepatocarcinoma resistance QTL 12 2.6 liver integrity trait (VT:0010547) volume of individual liver tumorous lesion (CMO:0001078) 3 29463235 118376539 Rat 1581568 Rf53 Renal function QTL 53 urine total protein amount (VT:0000032) urine protein excretion rate to body weight ratio (CMO:0001099) 3 56395968 161299569 Rat 7387306 Bw124 Body weight QTL 124 3.2 0.0003 body mass (VT:0001259) body weight (CMO:0000012) 3 84091273 129091273 Rat 1578754 Stresp16 Stress response QTL 16 4 0.001 blood renin amount (VT:0003349) plasma renin activity level (CMO:0000116) 3 112681431 157681431 Rat 1300111 Rf12 Renal function QTL 12 3.78 renal blood flow trait (VT:2000006) absolute change in renal blood flow rate (CMO:0001168) 3 61017749 121056321 Rat 1600376 Arunc5 Aerobic running capacity QTL 5 0.21 exercise endurance trait (VT:0002332) maximum distance run on treadmill (CMO:0001406) 3 73376539 118376539 Rat 8694437 Bw167 Body weight QTL 167 22.46 0.001 retroperitoneal fat pad mass (VT:0010430) retroperitoneal fat pad weight to body weight ratio (CMO:0000635) 3 91797474 136797474 Rat 8662816 Vetf4 Vascular elastic tissue fragility QTL 4 4 renal artery integrity trait (VT:0010642) number of ruptures of the internal elastic lamina of the renal arteries (CMO:0002563) 3 59242096 157323038 Rat 1559282 Emca5 Estrogen-induced mammary cancer QTL 5 3.9 mammary gland integrity trait (VT:0010552) percentage of study population developing mammary tumors during a period of time (CMO:0000948) 3 43827364 169034231 Rat 1581503 Cm58 Cardiac mass QTL 58 2.7 0.05 heart left ventricle mass (VT:0007031) heart left ventricle weight to body weight ratio (CMO:0000530) 3 43827364 121056321 Rat 1354611 Despr2 Despair related QTL 2 3.03 0.0028 locomotor behavior trait (VT:0001392) amount of time spent in voluntary immobility (CMO:0001043) 3 97084464 142084464 Rat 631649 Bp123 Blood pressure QTL 123 3.2 arterial blood pressure trait (VT:2000000) systolic blood pressure (CMO:0000004) 3 89772419 134772419 Rat 631841 Niddm39 Non-insulin dependent diabetes mellitus QTL 39 3.36 blood glucose amount (VT:0000188) blood glucose level (CMO:0000046) 3 94856903 159898684 Rat 1358204 Insglur1 Insulin/glucose ratio QTL 1 3.8 blood glucose amount (VT:0000188) serum glucose level (CMO:0000543) 3 115638168 135181505 Rat 619618 Rf3 Renal disease susceptibility QTL 3 6.5 0.001 urine albumin amount (VT:0002871) urine albumin excretion rate to body weight ratio (CMO:0001270) 3 107693393 152693393 Rat 12879848 Bw181 Body weght QTL 181 0.015 body mass (VT:0001259) body weight (CMO:0000012) 3 70348525 121056321 Rat 2301971 Cm71 Cardiac mass QTL 71 4.63 heart left ventricle mass (VT:0007031) heart left ventricle weight (CMO:0000776) 3 41874578 155617519 Rat 2312659 Slep7 Serum leptin concentration QTL 7 0.001 blood leptin amount (VT:0005667) serum leptin level (CMO:0000780) 3 98535255 168026850 Rat 1358885 Bp251 Blood pressure QTL 251 3.8 arterial blood pressure trait (VT:2000000) mean arterial blood pressure (CMO:0000009) 3 14489145 121056321 Rat 2301970 Bw81 Body weight QTL 81 5.19 body mass (VT:0001259) body weight (CMO:0000012) 3 41874578 155617519 Rat 1581546 Pur13 Proteinuria QTL 13 2.93 0.0335 urine total protein amount (VT:0000032) urine protein excretion rate (CMO:0000759) 3 78196190 146592722 Rat 631665 Bw8 Body weight QTL 8 5.5 body mass (VT:0001259) body weight (CMO:0000012) 3 50437042 119183768 Rat 1331758 Bp207 Blood pressure QTL 207 2.848 arterial blood pressure trait (VT:2000000) mean arterial blood pressure (CMO:0000009) 3 112287552 135181505 Rat 1358888 Bp264 Blood pressure QTL 264 4.43 arterial blood pressure trait (VT:2000000) mean arterial blood pressure (CMO:0000009) 3 14489145 121056321 Rat 2293087 Iddm27 Insulin dependent diabetes mellitus QTL 27 2.68 blood glucose amount (VT:0000188) blood glucose level (CMO:0000046) 3 97551417 147415807 Rat 2312670 Bw94 Body weight QTL 94 0.01 inguinal fat pad mass (VT:0010424) inguinal fat pad weight to body weight ratio (CMO:0001253) 3 98535255 168026850 Rat 724532 Cm17 Cardiac mass QTL 17 2 heart mass (VT:0007028) calculated heart weight (CMO:0000073) 3 95735366 140735366 Rat
RH139042
Rat Assembly Chr Position (strand) Source JBrowse mRatBN7.2 3 116,357,595 - 116,357,833 (+) MAPPER mRatBN7.2 Rnor_6.0 3 121,655,724 - 121,655,961 NCBI Rnor6.0 Rnor_5.0 3 128,358,809 - 128,359,046 UniSTS Rnor5.0 RGSC_v3.4 3 116,730,164 - 116,730,401 UniSTS RGSC3.4 Celera 3 115,182,983 - 115,183,220 UniSTS RH 3.4 Map 3 998.2 UniSTS Cytogenetic Map 3 q36 UniSTS
RH140641
Rat Assembly Chr Position (strand) Source JBrowse mRatBN7.2 3 116,358,088 - 116,358,286 (+) MAPPER mRatBN7.2 Rnor_6.0 3 121,656,217 - 121,656,414 NCBI Rnor6.0 Rnor_5.0 3 128,358,356 - 128,358,553 UniSTS Rnor5.0 RGSC_v3.4 3 116,730,657 - 116,730,854 UniSTS RGSC3.4 Celera 3 115,183,476 - 115,183,673 UniSTS RH 3.4 Map 3 997.9 UniSTS Cytogenetic Map 3 q36 UniSTS
Click on a value in the shaded box below the category label to view a detailed expression data table for that system.
alimentary part of gastrointestinal system
9
11
49
113
91
90
59
25
59
6
218
97
93
45
60
31
Too many to show, limit is 500. Download them if you would like to view them all.
Ensembl Acc Id:
ENSRNOT00000024882 ⟹ ENSRNOP00000024882
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source mRatBN7.2 Ensembl 3 116,333,889 - 116,358,379 (+) Ensembl Rnor_6.0 Ensembl 3 121,632,043 - 121,656,506 (+) Ensembl
RefSeq Acc Id:
NM_031773 ⟹ NP_113961
RefSeq Status:
VALIDATED
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source GRCr8 3 136,787,130 - 136,811,608 (+) NCBI mRatBN7.2 3 116,333,910 - 116,358,385 (+) NCBI Rnor_6.0 3 121,632,043 - 121,656,506 (+) NCBI Rnor_5.0 3 128,358,264 - 128,382,727 (-) NCBI RGSC_v3.4 3 116,706,483 - 116,730,946 (+) RGD Celera 3 115,159,305 - 115,183,765 (+) RGD
Sequence:
TGAATTGGTCCACGAGTGGAGTCGTAGCTCCGGTTTCCCGTCCGGGGCTCGCAGAAGCATGGATGTCGACAGCCGGTGGCGGAACCTGCCCAGCGGGCCCAGCCTAAAGCATTTAACCGACCCCTCGT
hide sequence
RefSeq Acc Id:
NP_113961 ⟸ NM_031773
- UniProtKB:
O54888 (UniProtKB/Swiss-Prot), F1LM57 (UniProtKB/TrEMBL), A6HQ47 (UniProtKB/TrEMBL)
- Sequence:
MDVDSRWRNLPSGPSLKHLTDPSYAVPPEQQKAALQDLTRAHVDSFNYAVLEGLSHAVQAIPPFEFAFKDERISLTIVDAAISPPAVPKGTICKELNIYPAECRGRRSTYRGKLTADISWAVNGVPKG
hide sequence
Ensembl Acc Id:
ENSRNOP00000024882 ⟸ ENSRNOT00000024882
RGD ID: 13692419 Promoter ID: EPDNEW_R2944 Type: multiple initiation site Name: Polr1b_1 Description: RNA polymerase I subunit B SO ACC ID: SO:0000170 Source: EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/ ) Experiment Methods: Single-end sequencing. Position: Rat Assembly Chr Position (strand) Source Rnor_6.0 3 121,632,035 - 121,632,095 EPDNEW
Date
Current Symbol
Current Name
Previous Symbol
Previous Name
Description
Reference
Status
2016-07-21
Polr1b
RNA polymerase I subunit B
Polr1b
polymerase (RNA) I subunit B
Nomenclature updated to reflect human and mouse nomenclature
1299863 APPROVED
2016-03-09
Polr1b
polymerase (RNA) I subunit B
Polr1b
polymerase (RNA) I polypeptide B
Nomenclature updated to reflect human and mouse nomenclature
1299863 APPROVED
2008-11-06
Polr1b
polymerase (RNA) I polypeptide B
Rpo1-2
RNA polymerase 1-2
Nomenclature updated to reflect human and mouse nomenclature
1299863 APPROVED
2004-02-11
Ptpn23
RNA polymerase 1-2
Rpo1-2
RNA polymerase I (127 kDa subunit)
Name updated to reflect Human and Mouse nomenclature
625702 APPROVED
2002-08-07
Rpo1-2
RNA polymerase I (127 kDa subunit)
Symbol and Name status set to provisional
70820 PROVISIONAL
