H4c8 (H4 clustered histone 8) - Rat Genome Database

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Gene: H4c8 (H4 clustered histone 8) Rattus norvegicus
Analyze
Symbol: H4c8 (Ensembl: H4c14)
Name: H4 clustered histone 8 (Ensembl:H4 clustered histone 14)
RGD ID: 620814
Description: Predicted to be a structural constituent of chromatin. Predicted to be involved in negative regulation of megakaryocyte differentiation and nucleosome assembly. Predicted to be located in nucleoplasm. Predicted to be part of CENP-A containing nucleosome. Predicted to be active in nucleus. Orthologous to several human genes including H4C9 (H4 clustered histone 9); PARTICIPATES IN systemic lupus erythematosus pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; aldehydo-D-glucose; D-glucose.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: germinal histone H4; germinal histone H4 gene; H1ft; H4c16; H4c2; H4f16; Hist1h4b; Hist1h4m; Hist4; Hist4h4; histone cluster 1 H4 family member B; histone cluster 1, H4b; histone H4
RGD Orthologs
Human
Mouse
Bonobo
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81747,176,246 - 47,180,690 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1747,400,471 - 47,470,855 (-)EnsemblGRCr8
GRCr8 Ensembl1741,953,594 - 41,958,964 (-)EnsemblGRCr8
GRCr8 Ensembl1741,797,152 - 41,806,539 (+)EnsemblGRCr8
GRCr8 Ensembl4171,403,627 - 171,403,938 (-)EnsemblGRCr8
mRatBN7.21742,480,467 - 42,484,912 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1742,480,313 - 42,485,370 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1744,530,209 - 44,534,658 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01749,289,303 - 49,293,753 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01743,780,258 - 43,784,712 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01744,522,144 - 44,526,587 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1744,522,140 - 44,526,583 (+)Ensemblrn6Rnor6.0
Rnor_5.01758,943,971 - 58,948,414 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41750,113,499 - 50,117,942 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1753,976,729 - 53,981,173 (-)NCBICelera
RGSC_v3.11750,116,339 - 50,120,783 (+)NCBI
Cytogenetic Map17p11NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(-)-epigallocatechin 3-gallate  (ISO)
1,2,4-trichloro-5-(2,5-dichlorophenyl)benzene  (ISO)
1,2-dimethylhydrazine  (ISO)
2,2',4,4',5,5'-hexachlorobiphenyl  (ISO)
2,2',5,5'-tetrachlorobiphenyl  (ISO)
2,3',4,4',5-Pentachlorobiphenyl  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4,4'-trichlorobiphenyl  (ISO)
2,4-diaminotoluene  (ISO)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
4,4'-sulfonyldiphenol  (ISO)
4-hydroxyphenyl retinamide  (ISO)
acrolein  (ISO)
aldehydo-D-glucose  (EXP)
alpha-pinene  (ISO)
aristolochic acid A  (ISO)
arsenite(3-)  (ISO)
benzo[a]pyrene  (ISO)
berberine  (ISO)
bilirubin IXalpha  (ISO)
bisphenol A  (ISO)
bisphenol F  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
caffeine  (ISO)
cannabidiol  (ISO)
carbon nanotube  (ISO)
choline  (ISO)
chromium(6+)  (ISO)
ciguatoxin CTX1B  (ISO)
cisplatin  (ISO)
copper(II) sulfate  (ISO)
cyclosporin A  (ISO)
D-glucose  (EXP)
dexamethasone  (ISO)
dioxygen  (ISO)
folic acid  (ISO)
genistein  (ISO)
gentamycin  (EXP)
glucose  (EXP)
glyphosate  (ISO)
indinavir  (ISO)
indometacin  (ISO)
iron dichloride  (ISO)
L-methionine  (ISO)
lamivudine  (ISO)
Licochalcone B  (ISO)
lipopolysaccharide  (ISO)
methidathion  (ISO)
methoxyacetic acid  (EXP)
N-methyl-4-phenylpyridinium  (EXP)
N-Nitrosopyrrolidine  (ISO)
okadaic acid  (ISO)
ozone  (ISO)
paracetamol  (ISO)
PCB138  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
propanal  (ISO)
propiconazole  (ISO)
saquinavir  (ISO)
silicon dioxide  (ISO)
silver atom  (ISO)
silver(0)  (ISO)
sodium arsenite  (ISO)
Triptolide  (ISO)
troglitazone  (ISO)
trovafloxacin  (ISO)
tungsten  (ISO)
valproic acid  (ISO)
vancomycin  (ISO)
zidovudine  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. A rat histone H4 gene closely associated with the testis-specific H1t gene. Grimes S, etal., Exp Cell Res 1987 Dec;173(2):534-45.
3. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
4. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
6. Protein-DNA interactions within the rat histone H4t promoter. Wolfe SA and Grimes SR, J Biol Chem 1991 Apr 5;266(10):6637-43.
Additional References at PubMed
PMID:1582415   PMID:2920170   PMID:5171427   PMID:7932740   PMID:10318873   PMID:11319220   PMID:12477932   PMID:14585971   PMID:14718166   PMID:15489334   PMID:15607978   PMID:16042990  
PMID:16621524   PMID:16939626   PMID:18474616   PMID:20498094   PMID:21357467   PMID:21636898   PMID:22368283   PMID:23979707   PMID:24699735   PMID:25615412   PMID:25931508   PMID:29476059  
PMID:32357304   PMID:35352799  


Genomics

Comparative Map Data
H4c8
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81747,176,246 - 47,180,690 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1747,400,471 - 47,470,855 (-)EnsemblGRCr8
GRCr8 Ensembl1741,953,594 - 41,958,964 (-)EnsemblGRCr8
GRCr8 Ensembl1741,797,152 - 41,806,539 (+)EnsemblGRCr8
GRCr8 Ensembl4171,403,627 - 171,403,938 (-)EnsemblGRCr8
mRatBN7.21742,480,467 - 42,484,912 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1742,480,313 - 42,485,370 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1744,530,209 - 44,534,658 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01749,289,303 - 49,293,753 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01743,780,258 - 43,784,712 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01744,522,144 - 44,526,587 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1744,522,140 - 44,526,583 (+)Ensemblrn6Rnor6.0
Rnor_5.01758,943,971 - 58,948,414 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41750,113,499 - 50,117,942 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1753,976,729 - 53,981,173 (-)NCBICelera
RGSC_v3.11750,116,339 - 50,120,783 (+)NCBI
Cytogenetic Map17p11NCBI
H4C9
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38627,139,282 - 27,139,678 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl627,139,282 - 27,140,640 (+)Ensemblhg38GRCh38
GRCh37627,107,061 - 27,107,457 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36627,215,067 - 27,215,436 (+)NCBIBuild 36Build 36hg18NCBI36
Build 34627,215,066 - 27,215,436NCBI
Celera628,713,087 - 28,713,456 (+)NCBICelera
Cytogenetic Map6p22.1NCBI
HuRef626,915,149 - 26,915,518 (+)NCBIHuRef
CHM1_1627,109,410 - 27,109,779 (+)NCBICHM1_1
T2T-CHM13v2.0627,008,097 - 27,008,493 (+)NCBIT2T-CHM13v2.0
H4c8
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391323,715,214 - 23,715,648 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1323,715,220 - 23,715,689 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm381323,531,044 - 23,531,478 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1323,531,050 - 23,531,519 (+)Ensemblmm10GRCm38
MGSCv371323,622,919 - 23,623,388 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361323,538,515 - 23,538,984 (+)NCBIMGSCv36mm8
Celera1323,762,985 - 23,763,454 (+)NCBICelera
Cytogenetic Map13A3.1NCBI
cM Map139.77NCBI
LOC100981824
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2541,784,458 - 41,790,190 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1637,785,914 - 37,791,120 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0626,971,978 - 26,975,626 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1627,633,627 - 27,637,235 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl627,634,245 - 27,634,556 (+)EnsemblpanPan2panpan1.1
LOC101967236
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404946816,126 - 817,757 (-)NCBIHiC_Itri_2
SpeTri2.0NW_0049366712,803,784 - 2,804,173 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
H4C9
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1721,224,973 - 21,225,379 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
H4C9
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11745,370,125 - 45,370,754 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1114,670,283 - 14,670,591 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366604426,834,357 - 26,834,758 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0

Variants

.
Variants in H4c8
23 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:234
Count of miRNA genes:146
Interacting mature miRNAs:162
Transcripts:ENSRNOT00000043151
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
8552966Pigfal18Plasma insulin-like growth factor 1 level QTL 188.7blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)171286094257860942Rat
2302377Scl61Serum cholesterol level QTL 614.36blood HDL cholesterol amount (VT:0000184)serum high density lipoprotein cholesterol level (CMO:0000361)17622199858177198Rat
1354654Spl7Serum phospholipid level QTL 75.5blood phospholipid amount (VT:0006084)blood phospholipid level (CMO:0001169)173803135483031354Rat
70157Niddm32Non-insulin dependent diabetes mellitus QTL 324.34blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)172266079955604694Rat
9589151Insul30Insulin level QTL 308.820.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)171286094257860942Rat
1598871Memor5Memory QTL 55.3exploratory behavior trait (VT:0010471)total horizontal distance resulting from voluntary locomotion in an experimental apparatus (CMO:0001443)174096801789341781Rat
1354628Stl13Serum triglyceride level QTL 133.8blood triglyceride amount (VT:0002644)blood triglyceride level (CMO:0000118)172149899450592236Rat
1354629Scl31Serum cholesterol level QTL 314.1blood cholesterol amount (VT:0000180)blood total cholesterol level (CMO:0000051)173803135483031354Rat
1600398Edcs5Endometrial carcinoma susceptibility QTL 52.2uterus morphology trait (VT:0001120)percentage of study population developing endometrioid carcinoma during a period of time (CMO:0001759)173544694975762341Rat
1559055Bp278Blood pressure QTL 2780.04arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)172385892668858926Rat
9590154Scort9Serum corticosterone level QTL 923.570.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)171286094257860942Rat
152025238Slep14Serum leptin concentration QTL 144.62blood leptin amount (VT:0005667)172439059584432719Rat
1354638Insul1Insulin level QTL 14.8blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)173803135483031354Rat
1354635Bp245Blood pressure QTL 2456arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)173803135483031354Rat
1331765Hrtrt15Heart rate QTL 154.094heart pumping trait (VT:2000009)heart rate (CMO:0000002)171553702560531414Rat
7411666Foco31Food consumption QTL 3111.40.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)171286094257860942Rat
1300148Bp192Blood pressure QTL 1923.47arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)174605012691050126Rat
2303627Vencon8Ventilatory control QTL 80.001respiration trait (VT:0001943)tidal volume (CMO:0000222)17473353449733534Rat
4889955Bss93Bone structure and strength QTL 934.4tibia size trait (VT:0100001)tibia cortical bone volume to tibia total bone volume ratio (CMO:0001727)172723344565155015Rat
2324621Coatc5Coat color QTL 5coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)174265489587654895Rat
1300129Rf25Renal function QTL 253.03blood creatinine amount (VT:0005328)creatinine clearance (CMO:0000765)174106235286062352Rat
1354663Bvd5Brain ventricular dilatation QTL 53.510.001brain ventricle morphology trait (VT:0000822)hydrocephalus severity score (CMO:0001881)173219953486201342Rat
152023740Bp406Blood pressure QTL 4066.06arterial blood pressure trait (VT:2000000)172413612784432719Rat
7488966Bp370Blood pressure QTL 3700.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)172385892668858926Rat
152023737Bp405Blood pressure QTL 4055.06arterial blood pressure trait (VT:2000000)2413612784432719Rat
152023736Bp404Blood pressure QTL 4043.78arterial blood pressure trait (VT:2000000)172413612784432719Rat
724528Uae4Urinary albumin excretion QTL 44.90.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)173604553781045537Rat
70210Cm15Cardiac mass QTL 156.5heart right ventricle mass (VT:0007033)heart right ventricle wet weight (CMO:0000072)173006647275066472Rat
152023626Bp403Blood pressure QTL 4033.86arterial blood pressure trait (VT:2000000)172413612784432719Rat
2301412Kidm40Kidney mass QTL 400.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)174238816487388164Rat
9590107Sffal7Serum free fatty acids level QTL 74.810.001blood free fatty acid amount (VT:0001553)plasma free fatty acids level (CMO:0000546)173310464578104645Rat
724549Niddm56Non-insulin dependent diabetes mellitus QTL 560.03blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)173219953449497050Rat
1581512Cm55Cardiac mass QTL 552.80.05heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)172723344583975845Rat
10054088Scort28Serum corticosterone level QTL 282.040.0102blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)17473353449733534Rat
61394Bp8Blood pressure QTL 82.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)172328632264246472Rat
9589057Scfw6Subcutaneous fat weight QTL 68.620.001subcutaneous adipose mass (VT:1000472)abdominal subcutaneous fat pad weight (CMO:0002069)171286094257860942Rat
2317045Aia11Adjuvant induced arthritis QTL 114.06joint integrity trait (VT:0010548)left rear ankle joint diameter (CMO:0002149)172652205171522051Rat
10450503Bp386Blood pressure QTL 3860.28arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)172201970567019705Rat
9590088Insglur7Insulin/glucose ratio QTL 720.380.001blood insulin amount (VT:0001560)calculated plasma insulin level (CMO:0002170)171286094257860942Rat
2313854Bp343Blood pressure QTL 3433.9life span trait (VT:0005372)age at time of death (CMO:0001193)173219953455604694Rat
2317053Aia25Adjuvant induced arthritis QTL 252.69joint integrity trait (VT:0010548)right rear ankle joint diameter (CMO:0002150)171060469455604694Rat
8552928Pigfal9Plasma insulin-like growth factor 1 level QTL 99blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)173310464578104645Rat
12904736Cm121Cardiac mass QTL 1210.043heart mass (VT:0007028)heart wet weight to body weight ratio (CMO:0002408)174238816487388164Rat
12903980Cm120Cardiac mass QTL 1200.002heart right ventricle mass (VT:0007033)heart right ventricle weight to body weight ratio (CMO:0000914)172385892668858926Rat
4889891Eae32Experimental allergic encephalomyelitis QTL 324.80.0002nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis severity score (CMO:0001419)172723344572233445Rat
12903981Am17Aortic mass QTL 170.001aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)172385892668858926Rat
12903982Kidm70Kidney mass QTL 700.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)172385892668858926Rat
12903978Cm118Cardiac mass QTL 1180.001heart mass (VT:0007028)heart wet weight to body weight ratio (CMO:0002408)172385892668858926Rat
1354619Bp242Blood pressure QTL 2426.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)173768787782687877Rat
12903979Cm119Cardiac mass QTL 1190.001heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)172385892668858926Rat

Markers in Region
RH129544  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21742,484,566 - 42,484,785 (+)MAPPERmRatBN7.2
Rnor_6.01744,526,242 - 44,526,460NCBIRnor6.0
Rnor_5.01758,944,098 - 58,944,316UniSTSRnor5.0
RGSC_v3.41750,117,597 - 50,117,815UniSTSRGSC3.4
Celera1753,976,856 - 53,977,074UniSTS
Cytogenetic Map17q11UniSTS
RH129874  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21742,484,582 - 42,484,785 (+)MAPPERmRatBN7.2
Rnor_6.01744,526,258 - 44,526,460NCBIRnor6.0
Rnor_5.01758,944,098 - 58,944,300UniSTSRnor5.0
RGSC_v3.41750,117,613 - 50,117,815UniSTSRGSC3.4
Celera1753,976,856 - 53,977,058UniSTS
Cytogenetic Map17q11UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
10 12 61 134 57 60 41 86 41 298 168 11 125 71 73 19 17 17

Sequence


RefSeq Acc Id: NM_022686   ⟹   NP_073177
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81747,176,246 - 47,180,690 (+)NCBI
mRatBN7.21742,480,467 - 42,484,912 (+)NCBI
Rnor_6.01744,522,144 - 44,526,587 (+)NCBI
Rnor_5.01758,943,971 - 58,948,414 (-)NCBI
RGSC_v3.41750,113,499 - 50,117,942 (+)RGD
Celera1753,976,729 - 53,981,173 (-)RGD
Sequence:
RefSeq Acc Id: NP_073177   ⟸   NM_022686
- UniProtKB: Q5BM23 (UniProtKB/Swiss-Prot),   Q7M0E8 (UniProtKB/Swiss-Prot),   P62804 (UniProtKB/Swiss-Prot),   A6KLQ0 (UniProtKB/TrEMBL)
- Sequence:
Protein Domains
TATA box binding protein associated factor (TAF)

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P62804-F1-model_v2 AlphaFold P62804 1-103 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:620814 AgrOrtholog
BioCyc Gene G2FUF-9296 BioCyc
Ensembl Genes ENSRNOG00000032224 UniProtKB/Swiss-Prot
  ENSRNOG00000054017 Ensembl, UniProtKB/Swiss-Prot
  ENSRNOG00000063552 UniProtKB/Swiss-Prot
  ENSRNOG00000064025 UniProtKB/Swiss-Prot
  ENSRNOG00000065263 Ensembl, UniProtKB/Swiss-Prot
  ENSRNOG00000066473 Ensembl, UniProtKB/Swiss-Prot
  ENSRNOG00000067648 Ensembl, UniProtKB/Swiss-Prot
  ENSRNOG00000070513 Ensembl, UniProtKB/Swiss-Prot
  ENSRNOG00000070706 UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000040210.5 UniProtKB/Swiss-Prot
  ENSRNOT00000080490.2 UniProtKB/Swiss-Prot
  ENSRNOT00000088408.2 UniProtKB/Swiss-Prot
  ENSRNOT00000105806.1 UniProtKB/Swiss-Prot
  ENSRNOT00000106060.1 UniProtKB/Swiss-Prot
  ENSRNOT00000107328.1 UniProtKB/Swiss-Prot
  ENSRNOT00000112120.1 UniProtKB/Swiss-Prot
  ENSRNOT00000112947.1 UniProtKB/Swiss-Prot
  ENSRNOT00000114507.1 UniProtKB/Swiss-Prot
  ENSRNOT00000115294.1 UniProtKB/Swiss-Prot
  ENSRNOT00000117583.1 UniProtKB/Swiss-Prot
  ENSRNOT00000120238.1 UniProtKB/Swiss-Prot
Gene3D-CATH 1.10.20.10 UniProtKB/Swiss-Prot
InterPro CENP-T/H4_C UniProtKB/Swiss-Prot
  Histone-fold UniProtKB/Swiss-Prot
  Histone_H4 UniProtKB/Swiss-Prot
  Histone_H4_CS UniProtKB/Swiss-Prot
  TAF_TATA-bd UniProtKB/Swiss-Prot
KEGG Report rno:291152 UniProtKB/Swiss-Prot
  rno:295277 UniProtKB/Swiss-Prot
  rno:64627 UniProtKB/Swiss-Prot
NCBI Gene 64627 ENTREZGENE
PANTHER HISTONE H4 UniProtKB/Swiss-Prot
Pfam CENP-T_C UniProtKB/Swiss-Prot
PhenoGen H4c8 PhenoGen
PRINTS HISTONEH4 UniProtKB/Swiss-Prot
PROSITE HISTONE_H4 UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000032224 RatGTEx
  ENSRNOG00000054017 RatGTEx
  ENSRNOG00000063552 RatGTEx
  ENSRNOG00000064025 RatGTEx
  ENSRNOG00000065263 RatGTEx
  ENSRNOG00000066473 RatGTEx
  ENSRNOG00000067648 RatGTEx
  ENSRNOG00000070513 RatGTEx
  ENSRNOG00000070706 RatGTEx
SMART SM00417 UniProtKB/Swiss-Prot
  TAF UniProtKB/Swiss-Prot
Superfamily-SCOP SSF47113 UniProtKB/Swiss-Prot
UniProt A6KLQ0 ENTREZGENE, UniProtKB/TrEMBL
  H4_RAT UniProtKB/Swiss-Prot, ENTREZGENE
  Q5BM23 ENTREZGENE
  Q7M0E8 ENTREZGENE
UniProt Secondary P02304 UniProtKB/Swiss-Prot
  P02305 UniProtKB/Swiss-Prot
  Q5BM23 UniProtKB/Swiss-Prot
  Q7M0E8 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2025-07-14 H4c8  H4 clustered histone 8  Hist1h4b  histone cluster 1 H4 family member B  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2017-05-23 Hist1h4b  histone cluster 1 H4 family member B  Hist1h4b  histone cluster 1, H4b  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-11-07 Hist1h4b  histone cluster 1, H4b    germinal histone H4 gene  Name updated 1299863 APPROVED
2005-02-24 Hist1h4b  germinal histone H4 gene  H1ft  germinal histone H4 gene  Data merged from RGD:628839 737654 APPROVED
2004-09-10 Hist1h4b  germinal histone H4 gene  Hist4    Symbol and Name updated 1299863 APPROVED
2003-02-27 H1ft  germinal histone H4 gene      Symbol and Name status set to provisional 70820 PROVISIONAL
2002-08-07 Hist4  germinal histone H4 gene      Symbol and Name status set to provisional 70820 PROVISIONAL

RGD Curation Notes
Note Type Note Reference
gene_regulation expression is down-regulated in postmeiotic early spermatids 632841