Btnl2 (butyrophilin-like 2) - Rat Genome Database

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Gene: Btnl2 (butyrophilin-like 2) Rattus norvegicus
Analyze
Symbol: Btnl2
Name: butyrophilin-like 2
RGD ID: 620731
Description: Predicted to enable signaling receptor binding activity. Predicted to be involved in T cell receptor signaling pathway and regulation of cytokine production. Predicted to act upstream of or within negative regulation of T cell receptor signaling pathway; positive regulation of T cell proliferation; and positive regulation of interleukin-2 production. Predicted to be located in membrane. Predicted to be active in external side of plasma membrane. Human ortholog(s) of this gene implicated in several diseases, including Graves' disease; Kawasaki disease; berylliosis; rheumatoid arthritis; and ulcerative colitis. Orthologous to human BTNL2 (butyrophilin like 2); INTERACTS WITH 1-naphthyl isothiocyanate; bisphenol A; endosulfan.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: BTL-II; butyrophilin-like 2 (MHC class II associated); butyrophilin-like protein 2; Ng9
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Black Rat
Alliance Orthologs
More Info more info ...
Is Marker For: Strains:   DA.E3-(Btnl2-RT1-DMb)
QTLs:   Tcs2  
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8204,492,100 - 4,505,932 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl204,492,111 - 4,505,932 (-)EnsemblGRCr8
mRatBN7.2204,490,169 - 4,504,002 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl204,489,517 - 4,503,341 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx205,254,364 - 5,265,996 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0204,616,104 - 4,627,736 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0205,088,388 - 5,099,896 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0204,140,184 - 4,156,365 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl204,141,878 - 4,154,978 (+)Ensemblrn6Rnor6.0
Rnor_5.0206,221,727 - 6,236,503 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4204,613,726 - 4,625,383 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera206,093,476 - 6,105,126 (-)NCBICelera
RGSC_v3.1204,701,740 - 4,702,792 (+)NCBI
Cytogenetic Map20p12NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Genetic analysis in young-age-of-onset Graves' disease reveals new susceptibility loci. Brown RS, etal., J Clin Endocrinol Metab. 2014 Jul;99(7):E1387-91. doi: 10.1210/jc.2013-4358. Epub 2014 Mar 31.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. BTNL2 gene polymorphisms may be associated with susceptibility to Kawasaki disease and formation of coronary artery lesions in Taiwanese children. Hsueh KC, etal., Eur J Pediatr. 2010 Jun;169(6):713-9. doi: 10.1007/s00431-009-1099-5. Epub 2009 Nov 1.
4. Analysis of the association between BTNL2 polymorphism and tuberculosis in Chinese Han population. Lian Y, etal., Infect Genet Evol. 2010 May;10(4):517-21. doi: 10.1016/j.meegid.2010.02.006. Epub 2010 Feb 20.
5. Exome sequencing identifies novel rheumatoid arthritis-susceptible variants in the BTNL2. Mitsunaga S, etal., J Hum Genet. 2013 Apr;58(4):210-5. doi: 10.1038/jhg.2013.2. Epub 2013 Jan 31.
6. Allelic variation in BTNL2 and susceptibility to tuberculosis in a South African population. Moller M, etal., Microbes Infect. 2007 Apr;9(4):522-8. Epub 2007 Jan 27.
7. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
8. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
9. Confirmation of the novel association at the BTNL2 locus with ulcerative colitis. Pathan S, etal., Tissue Antigens. 2009 Oct;74(4):322-9. doi: 10.1111/j.1399-0039.2009.01314.x. Epub 2009 Jul 29.
10. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
11. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
12. Comprehensive gene review and curation RGD comprehensive gene curation
13. BTNL2 allele associations with chronic beryllium disease in HLA-DPB1*Glu69-negative individuals. Sato H, etal., Tissue Antigens. 2007 Dec;70(6):480-6. Epub 2007 Oct 8.
14. Genetic characterization and susceptibility for sarcoidosis in Japanese patients: risk factors of BTNL2 gene polymorphisms and HLA class II alleles. Suzuki H, etal., Invest Ophthalmol Vis Sci. 2012 Oct 11;53(11):7109-15. doi: 10.1167/iovs.12-10491.
15. Sequence of a cDNA coding for a rat class II A alpha chain: extensive DNA and protein sequence identity to H-2 A alpha and HLA-DC1 alpha chains. Wallis AE and McMaster WR, Immunogenetics 1984;19(1):53-62.
Additional References at PubMed
PMID:15060004   PMID:16751379  


Genomics

Comparative Map Data
Btnl2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8204,492,100 - 4,505,932 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl204,492,111 - 4,505,932 (-)EnsemblGRCr8
mRatBN7.2204,490,169 - 4,504,002 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl204,489,517 - 4,503,341 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx205,254,364 - 5,265,996 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0204,616,104 - 4,627,736 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0205,088,388 - 5,099,896 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0204,140,184 - 4,156,365 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl204,141,878 - 4,154,978 (+)Ensemblrn6Rnor6.0
Rnor_5.0206,221,727 - 6,236,503 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4204,613,726 - 4,625,383 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera206,093,476 - 6,105,126 (-)NCBICelera
RGSC_v3.1204,701,740 - 4,702,792 (+)NCBI
Cytogenetic Map20p12NCBI
BTNL2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38632,393,339 - 32,407,181 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl632,393,339 - 32,407,181 (-)Ensemblhg38GRCh38
GRCh37632,361,116 - 32,374,958 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36632,470,491 - 32,482,878 (-)NCBIBuild 36Build 36hg18NCBI36
Build 34632,470,490 - 32,482,878NCBI
Celera633,929,258 - 33,941,628 (-)NCBICelera
Cytogenetic Map6p21.32NCBI
HuRef632,116,435 - 32,128,672 (-)NCBIHuRef
CHM1_1632,364,981 - 32,377,368 (-)NCBICHM1_1
T2T-CHM13v2.0632,246,262 - 32,260,103 (-)NCBIT2T-CHM13v2.0
Btnl2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391734,573,763 - 34,588,466 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1734,573,796 - 34,588,469 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm381734,354,789 - 34,369,492 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1734,354,822 - 34,369,495 (+)Ensemblmm10GRCm38
MGSCv371734,491,767 - 34,506,437 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361733,962,403 - 33,977,115 (+)NCBIMGSCv36mm8
Celera1737,117,517 - 37,137,992 (+)NCBICelera
Cytogenetic Map17B1NCBI
cM Map1717.98NCBI
Btnl2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554371,083,745 - 1,101,730 (-)Ensembl
ChiLan1.0NW_0049554371,084,330 - 1,101,751 (-)NCBIChiLan1.0ChiLan1.0
BTNL2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2546,879,850 - 46,942,392 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1642,844,186 - 42,903,429 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0632,067,223 - 32,126,032 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1632,944,694 - 32,950,097 (-)NCBIPanPan1.1PanPan1.1panPan2
BTNL2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1122,085,589 - 2,106,787 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl122,086,324 - 2,107,124 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha122,235,540 - 2,256,084 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0122,362,341 - 2,383,324 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl122,362,672 - 2,383,780 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1122,085,680 - 2,106,664 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0122,166,791 - 2,187,786 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0122,240,782 - 2,261,746 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Btnl2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494636,973,660 - 36,993,788 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936727567,656 - 587,784 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_004936727567,656 - 587,784 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
BTNL2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl724,789,888 - 24,810,132 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1724,789,988 - 24,809,920 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2729,001,473 - 29,021,390 (-)NCBISscrofa10.2Sscrofa10.2susScr3
Btnl2
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v1187,058,234 - 7,071,945 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Btnl2
332 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:108
Count of miRNA genes:92
Interacting mature miRNAs:99
Transcripts:ENSRNOT00000060366
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
4889610Pancm3Pancreatic morphology QTL 33.750.001pancreas mass (VT:0010144)pancreas wet weight (CMO:0000626)20418947649189476Rat
2306850Pia40Pristane induced arthritis QTL 400.0001joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)2015332005306452Rat
1354642Despr15Despair related QTL 150.0027locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)20124164241Rat
70154Insul2Insulin level QTL 23.75blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)2016693431Rat
4889857Pur27Proteinuria QTL 2712.20.001urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)20127341128Rat
9590109Sffal8Serum free fatty acids level QTL 85.320.01blood free fatty acid amount (VT:0001553)plasma free fatty acids level (CMO:0000546)20129193376Rat
9590275Scort15Serum corticosterone level QTL 153.480.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)20129193376Rat
7175099Tcs2T cell selection QTL 2T cell selection trait (VT:0004917)expression2045059324695009Rat
6893685Bw111Body weight QTL 1112.70.004body mass (VT:0001259)body weight (CMO:0000012)20132578510Rat
61474Eae1Experimental allergic encephalomyelitis QTL 13nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis severity score (CMO:0001419)2016693431Rat
2317057Aia27Adjuvant induced arthritis QTL 272.83joint integrity trait (VT:0010548)right rear ankle joint diameter (CMO:0002150)20126925056Rat
1641915Colcr9Colorectal carcinoma resistance QTL 92.970.0024intestine integrity trait (VT:0010554)benign colorectal tumor number (CMO:0001795)20133724594Rat
7387283Uae44Urinary albumin excretion QTL 440.1712urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)20126128279Rat
7411668Foco32Food consumption QTL 3280.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)20136600300Rat
2305926Iddm37Insulin dependent diabetes mellitus QTL 376blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)20153308346533083Rat
1558640Prcs2Prostate cancer susceptibility QTL 23.3prostate integrity trait (VT:0010571)percentage of study population developing ventral prostate tumorous lesions during a period of time (CMO:0000943)20134066551Rat
1331772Cdexp2CD45RC expression in CD8 T cells QTL 25.7CD8-positive T cell quantity (VT:0008077)blood CD45RC(high) CD8 T cell count to CD45RC(low) CD8 T cell count ratio (CMO:0001990)20362632310078622Rat
8694189Bw153Body weight QTL 1533.130.001body mass (VT:0001259)body weight gain (CMO:0000420)20129193376Rat
1300152Bp195Blood pressure QTL 1953.46arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2036263239244918Rat
9589155Insul32Insulin level QTL 326.380.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)20129193376Rat
7411650Foco23Food consumption QTL 2320.70.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)20129193376Rat
61432Cia1Collagen induced arthritis QTL 1joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)20114100378Rat
2317851Alcrsp22Alcohol response QTL 223.20.05response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)20127341128Rat
1641893Alcrsp7Alcohol response QTL 7response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)20127341128Rat
9590252Scort12Serum corticosterone level QTL 1220.460.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)20136600300Rat

Markers in Region
D20Yum72  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2204,493,138 - 4,493,307 (-)MAPPERmRatBN7.2
Rnor_6.0204,152,575 - 4,152,743NCBIRnor6.0
Rnor_5.0206,232,713 - 6,232,881UniSTSRnor5.0
RGSC_v3.4204,615,961 - 4,616,129UniSTSRGSC3.4
Celera206,095,711 - 6,095,875UniSTS
Cytogenetic Map20p12UniSTS


Related Rat Strains
The following Strains have been annotated to Btnl2
DA.E3-(Btnl2-RT1-DMb)    


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 49 23 28 8 72 8 6 133 95 7 35 14 77 20 5 5

Sequence


Ensembl Acc Id: ENSRNOT00000060366   ⟹   ENSRNOP00000057110
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl204,492,111 - 4,504,267 (-)Ensembl
mRatBN7.2 Ensembl204,489,517 - 4,503,341 (-)Ensembl
Rnor_6.0 Ensembl204,143,321 - 4,154,978 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000077656   ⟹   ENSRNOP00000074272
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl204,141,878 - 4,153,132 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000120529   ⟹   ENSRNOP00000098182
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl204,492,111 - 4,505,932 (-)Ensembl
RefSeq Acc Id: NM_053815   ⟹   NP_446267
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8204,492,100 - 4,505,932 (-)NCBI
mRatBN7.2204,490,169 - 4,504,002 (-)NCBI
Rnor_6.0204,143,321 - 4,154,978 (+)NCBI
Rnor_5.0206,221,727 - 6,236,503 (+)NCBI
RGSC_v3.4204,613,726 - 4,625,383 (-)RGD
Celera206,093,476 - 6,105,126 (-)RGD
Sequence:
Protein Sequences
Protein RefSeqs NP_446267 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein CAE83949 (Get FASTA)   NCBI Sequence Viewer  
  EDL96795 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000098182
GenBank Protein Q6MG97 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_446267   ⟸   NM_053815
- UniProtKB: Q6MG97 (UniProtKB/Swiss-Prot),   A0A0A0MY44 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000074272   ⟸   ENSRNOT00000077656
Ensembl Acc Id: ENSRNOP00000057110   ⟸   ENSRNOT00000060366
Ensembl Acc Id: ENSRNOP00000098182   ⟸   ENSRNOT00000120529
Protein Domains
Ig-like   Ig-like V-type

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q6MG97-F1-model_v2 AlphaFold Q6MG97 1-454 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13701333
Promoter ID:EPDNEW_R11855
Type:initiation region
Name:Btnl2_1
Description:butyrophilin-like 2
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0204,141,895 - 4,141,955EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:620731 AgrOrtholog
BioCyc Gene G2FUF-4567 BioCyc
Ensembl Genes ENSRNOG00000028541 Ensembl, ENTREZGENE
Ensembl Transcript ENSRNOT00000120529 ENTREZGENE
Gene3D-CATH 2.60.40.10 UniProtKB/Swiss-Prot
InterPro BTN3A2-like_Ig-C UniProtKB/Swiss-Prot
  Ig-like_dom UniProtKB/Swiss-Prot
  Ig-like_dom_sf UniProtKB/Swiss-Prot
  Ig-like_fold UniProtKB/Swiss-Prot
  Ig_sub UniProtKB/Swiss-Prot
  Ig_sub2 UniProtKB/Swiss-Prot
  Ig_V-set UniProtKB/Swiss-Prot
  IgSF_BTN/MOG UniProtKB/Swiss-Prot
NCBI Gene Btnl2 ENTREZGENE
PANTHER BTNL2-RELATED UniProtKB/Swiss-Prot
  BUTYROPHILIN UniProtKB/Swiss-Prot
Pfam C2-set_3 UniProtKB/Swiss-Prot
  V-set UniProtKB/Swiss-Prot
PhenoGen Btnl2 PhenoGen
PROSITE IG_LIKE UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000028541 RatGTEx
SMART IGc2 UniProtKB/Swiss-Prot
  IGv UniProtKB/Swiss-Prot
  SM00409 UniProtKB/Swiss-Prot
Superfamily-SCOP SSF48726 UniProtKB/Swiss-Prot
UniProt A0A0A0MY44 ENTREZGENE, UniProtKB/TrEMBL
  A0ABK0L490_RAT UniProtKB/TrEMBL
  A6JJC9_RAT UniProtKB/TrEMBL
  BTNL2_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-03-16 Btnl2  butyrophilin-like 2  Btnl2  butyrophilin-like 2 (MHC class II associated)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2013-01-14 Btnl2  butyrophilin-like 2 (MHC class II associated)  Btnl2  butyrophilin-like 2  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-02-25 Btnl2  butyrophilin-like 2  Btnl2  butyrophilin-like 2 (MHC class II associated)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-01-20 Btnl2  butyrophilin-like 2 (MHC class II associated)      Symbol and Name status set to approved 1299863 APPROVED
2002-08-07 Btnl2  butyrophilin-like 2 (MHC class II associated)      Symbol and Name status set to provisional 70820 PROVISIONAL

RGD Curation Notes
Note Type Note Reference
gene_expression expressed in spleen 632355
gene_protein 129 amino acids 632355