Dvl1 Rat Gene (dishevelled, dsh homolog 1 (Drosophila))

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Keyword

Gene:
Dvl1 ( Rattus norvegicus )
dishevelled, dsh homolog 1 (Drosophila)
Description: signal transducer in the wnt-frizzled pathway; may be involved in wound healing and control of cell proliferation and/or migration after myocardial infarction
Synonyms: dvl-1; dishevelled 1;  (details...)
ArrayIDs: 6306863; 6067157; 5864695; 1369397_at; 6266571; 6008052; rc_AA963810_at; 6338508; rc_AI101690_at; 1397351_s_at; 5975454; 6010069; A_42_P538868; 6016365; 5974115; 6600085; 6716376; 6579664; 6699970; 6451343; 6150800; 1369997_at; 6067738; 6405044; 6239225; 5931482; 6634840; 5894716; 5883858; 6669166; 6323724; 6671613; GE1158415; 5693473;  (details...)
Gene Type: protein-coding

Additional Data

Homologs
Homo sapiens: DVL1     See the Human gene in context in:     UCSC     NCBI MapViewer

Mus musculus: Dvl1     See the Mouse gene in context in:     UCSC     NCBI MapViewer

Comparative Map Data
Species Symbol Map Name Chr. Position
Rattus norvegicus Dvl1 genome assembly 3.1 5 172716445 - 172728121
Rat Celera Assembly 5 164657716 - 164669383
RGSC genome assembly v3.4 5 172705951 - 172717626
Cytogenetic 5 q36
Mus musculus Dvl1 Mouse genome assembly build 36.1 4 155221521 - 155233412
Cytogenetic 4 4 E2
Homo sapiens DVL1 human genome assembly 1 1310581 - 1324438
Human genome assembly build 36.2 1 1260521 - 1274623
Cytogenetic 1 p36

View comparative maps:      NCBI MapViewer

Genome
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Annotation
Molecular Function

Gene Ontology

signal transducer activity,  protein binding,  Rac GTPase binding ... (details...)
Biological Process

Gene Ontology

multicellular organismal development,  negative regulation of protein kinase activity,  dendrite morphogenesis ... (details...)
Cellular Component

Gene Ontology

synapse,  cytoplasm,  cytoplasmic membrane-bounded vesicle ... (details...)
Disease

Ontology

Schizophrenia,  DiGeorge Syndrome (details...)
Pathway

Ontology

Wnt signaling pathway,  the planar cell polarity Wnt signaling pathway,  canonical Wnt signaling pathway (details...)
Other

Note Reference

excluded as a candidate gene for brain ischemia in the stroke-prone spontaneously hypertensive rat (SHRSP) because sequences in stroke-prone and control rats are identical 634738

External Links
Databases
DATABASE ID SOURCE
SMART: DAX IPI
SMART: PDZ IPI
SMART: DEP IPI
PROSITE: PDZ IPI
PROSITE: DIX IPI
PROSITE: DEP IPI
UNIPARC: UPI00001299A7 IPI
KEGG Report: rno:83721 ENTREZGENE
HomoloGene Group ID: 20926 ENTREZGENE
Germonline: 620632
Pfam: DEP IPI
Pfam: DIX IPI
Pfam: PDZ IPI
Pfam: Dishevelled IPI
KEGG Pathway: 05200 ENTREZGENE
KEGG Pathway: 05217 ENTREZGENE
KEGG Pathway: 05210 ENTREZGENE
KEGG Pathway: 04916 ENTREZGENE
KEGG Pathway: 04310 ENTREZGENE
KEGG Pathway: 04330 ENTREZGENE
InterPro: Dishevelled. IPI
InterPro: Wing_hlx_DNA_bd. IPI
InterPro: Dsh. IPI
InterPro: DIX. IPI
InterPro: Dishevelled_1. IPI
InterPro: PDZ/DHR/GLGF. IPI
InterPro: Dishevell. IPI
InterPro: Pleckstrin/G-protein_interact. IPI
Ensembl Protein: ENSRNOP00000026439 IPI
IPI: IPI00204871 IPI
Gene3D-CATH: Wing_hlx_DNA_bd IPI
Entrez Gene: Dvl1 ENTREZGENE
IMAGE_CLONE: IMAGE:5599217 IMAGE-MGC_LOAD
IMAGE_CLONE: IMAGE:7461890 IMAGE-MGC_LOAD
MGC_CLONE: MGC:72382 IMAGE-MGC_LOAD
MGC_CLONE: MGC:188669 IMAGE-MGC_LOAD
UniProt: DVL1_RAT IPI
Ensembl Genes: ENSRNOG00000019423 IPI
Superfamily-SCOP: PDZ IPI
PANTHER: Dsh IPI
PANTHER: Dishevelled_1 IPI
PRINTS: DISHEVELLED1. IPI
PRINTS: DISHEVELLED. IPI
Sequences
Nucleotide: CH473968 Get FASTA Search GEO Profiles
Nucleotide: BC090034 Get FASTA Search GEO Profiles
Nucleotide: BC062070 Get FASTA Search GEO Profiles
Nucleotide: AF143546 Get FASTA Search GEO Profiles
Nucleotide: AF143545 Get FASTA Search GEO Profiles
Nucleotide: BC160920 Get FASTA Search GEO Profiles
Nucleotide: AF143550 Get FASTA Search GEO Profiles
Nucleotide: AF143549 Get FASTA Search GEO Profiles
Nucleotide: AF143548 Get FASTA Search GEO Profiles
Nucleotide: AF143547 Get FASTA Search GEO Profiles
Nucleotide: NM_031820 Get FASTA Search GEO Profiles
(View all 11 Nucleotide Accessions)
Protein: AAD33897 Get FASTA
Protein: NP_114008 Get FASTA
Protein: AAD41492 Get FASTA
Protein: Q9WVB9 Get FASTA
Protein: AAI60920 Get FASTA
Protein: AAD33896 Get FASTA
Protein: EDL81336 Get FASTA
Protein: AAD41493 Get FASTA
(View all 8 Protein Accessions)
Clusters
UniGene: 144610

References
Curated References
12 references in RGD related to Dvl1

Other References
11 other references at PubMed related to Dvl1

Database Information
RGD ID 620632
History

Date Current Symbol Current Name Previous Symbol Previous name Status Description Reference

10-SEP-04: Dvl1 dishevelled, dsh homolog 1 (Drosophila) dishevelled 1 APPROVED Name updated 1299863

07-AUG-02: Dvl1 dishevelled 1 PROVISIONAL Symbol and Name status set to provisional 70820