Ajuba (ajuba LIM protein) - Rat Genome Database

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Gene: Ajuba (ajuba LIM protein) Rattus norvegicus
Analyze
Symbol: Ajuba
Name: ajuba LIM protein
RGD ID: 620407
Description: Predicted to enable several functions, including actin filament binding activity; alpha-catenin binding activity; and transcription corepressor activity. Predicted to be involved in several processes, including regulation of cellular response to hypoxia; regulation of gene expression; and regulation of intracellular signal transduction. Predicted to act upstream of or within several processes, including calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules; focal adhesion assembly; and negative regulation of macromolecule biosynthetic process. Located in cell-cell junction. Orthologous to human AJUBA (ajuba LIM protein); PARTICIPATES IN E-cadherin signaling pathway; INTERACTS WITH 1,3-dinitrobenzene; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: ajuba homolog; ajuba homolog (Xenopus laevis); Jub; jub, ajuba homolog; jub, ajuba homolog (Xenopus laevis); LIM domain-containing protein ajuba; MGC93830
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81531,989,796 - 32,000,042 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1531,989,799 - 32,000,042 (-)EnsemblGRCr8
mRatBN7.21528,019,775 - 28,031,537 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1528,019,778 - 28,030,021 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1529,858,600 - 29,868,825 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01531,005,812 - 31,016,041 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01529,255,934 - 29,266,128 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01533,208,210 - 33,218,456 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1533,208,216 - 33,218,456 (-)Ensemblrn6Rnor6.0
Rnor_5.01537,092,299 - 37,103,304 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41532,627,633 - 32,637,861 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1527,595,895 - 27,610,669 (-)NCBICelera
RGSC_v3.11532,644,597 - 32,652,711 (-)NCBI
Cytogenetic Map15p13NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(-)-epigallocatechin 3-gallate  (ISO)
(1->4)-beta-D-glucan  (ISO)
1,2-dimethylhydrazine  (ISO)
1,3-dinitrobenzene  (EXP)
14-Deoxy-11,12-didehydroandrographolide  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4-dinitrotoluene  (EXP)
3,4-dichloroaniline  (ISO)
4,4'-diaminodiphenylmethane  (ISO)
4,4'-sulfonyldiphenol  (ISO)
4-hydroxyphenyl retinamide  (ISO)
4-phenylbutyric acid  (ISO)
6-propyl-2-thiouracil  (EXP)
acetamide  (EXP)
aflatoxin B1  (ISO)
ammonium chloride  (EXP)
antirheumatic drug  (ISO)
aristolochic acid A  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
benzo[a]pyrene  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
cadmium atom  (ISO)
cadmium dichloride  (EXP,ISO)
caffeine  (ISO)
carbamazepine  (ISO)
carbon nanotube  (ISO)
CGP 52608  (ISO)
choline  (ISO)
cisplatin  (ISO)
cobalt dichloride  (ISO)
copper atom  (EXP,ISO)
copper(0)  (EXP,ISO)
copper(II) sulfate  (ISO)
coumarin  (ISO)
coumestrol  (ISO)
CU-O LINKAGE  (ISO)
Cuprizon  (EXP)
cyclosporin A  (ISO)
DDE  (ISO)
deoxynivalenol  (ISO)
Dibutyl phosphate  (ISO)
dibutyl phthalate  (EXP,ISO)
diuron  (EXP,ISO)
dorsomorphin  (ISO)
Enterolactone  (ISO)
entinostat  (ISO)
ethyl methanesulfonate  (ISO)
fenamidone  (ISO)
flutamide  (EXP)
folic acid  (ISO)
formaldehyde  (ISO)
FR900359  (ISO)
furan  (EXP)
gentamycin  (EXP)
glycidyl methacrylate  (ISO)
hydrogen peroxide  (ISO)
L-methionine  (ISO)
lead(0)  (ISO)
lipopolysaccharide  (ISO)
manganese atom  (ISO)
manganese(0)  (ISO)
manganese(II) chloride  (ISO)
methyl methanesulfonate  (ISO)
methylmercury chloride  (ISO)
mifepristone  (EXP)
mono(2-ethylhexyl) phthalate  (EXP)
Monobutylphthalate  (EXP)
N-nitrosodiethylamine  (ISO)
organophosphorus compound  (EXP)
orphenadrine  (EXP)
oxaliplatin  (EXP)
paracetamol  (ISO)
perfluorohexanesulfonic acid  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
phencyclidine  (ISO)
phenobarbital  (ISO)
pioglitazone  (ISO)
potassium chromate  (ISO)
potassium dichromate  (ISO)
quercetin  (ISO)
S-(1,2-dichlorovinyl)-L-cysteine  (ISO)
SB 431542  (ISO)
silicon dioxide  (ISO)
silver atom  (ISO)
silver(0)  (ISO)
sodium arsenite  (ISO)
sodium dichromate  (EXP)
tamoxifen  (ISO)
tert-butyl hydroperoxide  (ISO)
testosterone  (ISO)
tetrachloromethane  (ISO)
thioacetamide  (EXP)
thiram  (ISO)
titanium dioxide  (ISO)
topotecan  (EXP)
trichloroethene  (EXP)
trichostatin A  (ISO)
troglitazone  (ISO)
urethane  (ISO)
valproic acid  (ISO)
vinclozolin  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
adherens junction  (IBA)
anchoring junction  (IEA)
cell-cell junction  (IDA,IEA,ISO)
centrosome  (IEA)
cytoskeleton  (IEA)
cytosol  (IEA,ISO)
focal adhesion  (IEA,ISO)
lamellipodium  (IEA,ISO)
nucleus  (IBA,IEA,ISO)
P-body  (IBA,IEA,ISO)
plasma membrane  (IEA)
transcription regulator complex  (IBA,IEA,ISO)

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. The LIM protein Ajuba is recruited to cadherin-dependent cell junctions through an association with alpha-catenin. Marie H, etal., J Biol Chem. 2003 Jan 10;278(2):1220-8. Epub 2002 Nov 1.
3. The amino terminus of the glial glutamate transporter GLT-1 interacts with the LIM protein Ajuba. Marie H, etal., Mol Cell Neurosci 2002 Feb;19(2):152-64.
4. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
5. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
6. PID Annotation Import Pipeline Pipeline to import Pathway Interaction Database annotations from NCI into RGD
7. GOA pipeline RGD automated data pipeline
8. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:10330178   PMID:12477932   PMID:15728191   PMID:15870270   PMID:15870274   PMID:17909014   PMID:18331720   PMID:18347060   PMID:18805794   PMID:19376971   PMID:20303269   PMID:20616046  
PMID:22286099  


Genomics

Comparative Map Data
Ajuba
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81531,989,796 - 32,000,042 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1531,989,799 - 32,000,042 (-)EnsemblGRCr8
mRatBN7.21528,019,775 - 28,031,537 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1528,019,778 - 28,030,021 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1529,858,600 - 29,868,825 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01531,005,812 - 31,016,041 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01529,255,934 - 29,266,128 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01533,208,210 - 33,218,456 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1533,208,216 - 33,218,456 (-)Ensemblrn6Rnor6.0
Rnor_5.01537,092,299 - 37,103,304 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41532,627,633 - 32,637,861 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1527,595,895 - 27,610,669 (-)NCBICelera
RGSC_v3.11532,644,597 - 32,652,711 (-)NCBI
Cytogenetic Map15p13NCBI
AJUBA
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381422,971,177 - 22,982,551 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1422,971,177 - 22,982,551 (-)Ensemblhg38GRCh38
GRCh371423,440,386 - 23,451,760 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361422,510,249 - 22,521,691 (-)NCBIBuild 36Build 36hg18NCBI36
Build 341422,510,248 - 22,516,272NCBI
Celera143,303,299 - 3,314,741 (-)NCBICelera
Cytogenetic Map14q11.2NCBI
HuRef143,557,642 - 3,569,085 (-)NCBIHuRef
CHM1_11423,439,040 - 23,450,482 (-)NCBICHM1_1
T2T-CHM13v2.01417,171,795 - 17,183,169 (-)NCBIT2T-CHM13v2.0
Ajuba
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391454,804,926 - 54,815,118 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1454,804,929 - 54,815,015 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm381454,567,469 - 54,577,661 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1454,567,472 - 54,577,558 (-)Ensemblmm10GRCm38
MGSCv371455,186,309 - 55,196,253 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361453,521,677 - 53,531,621 (-)NCBIMGSCv36mm8
Celera1452,356,267 - 52,366,350 (-)NCBICelera
Cytogenetic Map14C2NCBI
cM Map1427.84NCBI
Ajuba
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540937,318,597 - 37,329,155 (+)Ensembl
ChiLan1.0NW_00495540937,318,597 - 37,329,068 (+)NCBIChiLan1.0ChiLan1.0
AJUBA
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21524,403,945 - 24,415,391 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11423,613,714 - 23,631,909 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0143,791,309 - 3,802,763 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11421,889,443 - 21,900,700 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1421,889,443 - 21,900,700 (-)EnsemblpanPan2panpan1.1
AJUBA
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.183,272,408 - 3,302,179 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl83,272,405 - 3,301,708 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha83,219,989 - 3,250,272 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.083,379,492 - 3,410,108 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl83,380,278 - 3,410,168 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.183,070,717 - 3,101,039 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.083,132,252 - 3,162,764 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.083,394,515 - 3,424,826 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Ajuba
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440864035,047,132 - 35,057,420 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049367221,331,566 - 1,341,863 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049367221,331,568 - 1,341,854 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
AJUBA
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl776,063,058 - 76,076,585 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1776,063,009 - 76,072,884 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
AJUBA
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12923,341,841 - 23,352,630 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2923,341,249 - 23,352,685 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366605923,067,978 - 23,079,304 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ajuba
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248209,552,287 - 9,563,472 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046248209,551,664 - 9,562,773 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Ajuba
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v11270,430,108 - 70,439,916 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Ajuba
23 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:846
Count of miRNA genes:307
Interacting mature miRNAs:391
Transcripts:ENSRNOT00000017753
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1641913Colcr2Colorectal carcinoma resistance QTL 26.570.0197intestine integrity trait (VT:0010554)poorly differentiated malignant colorectal tumor number (CMO:0002076)15231575947315759Rat
5684946Bss98Bone structure and strength QTL 983.90.0026tibia strength trait (VT:1000284)tibia ultimate force (CMO:0001734)15139411584Rat
1641887Alcrsp14Alcohol response QTL 14response to alcohol trait (VT:0010489)brain neurotensin receptor 1 density (CMO:0002068)15144836456Rat
738017Hcas7Hepatocarcinoma susceptibility QTL 72.91liver integrity trait (VT:0010547)liver nonremodeling tumorous lesion volume to total liver volume ratio (CMO:0001464)15231575953331089Rat
152025253Hrtrt24Heart rate QTL 243.82heart pumping trait (VT:2000009)153185580392671517Rat
10054130Srcrt8Stress Responsive Cort QTL 82.180.0085blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)152852773273527732Rat
10755503Bp391Blood pressure QTL 3912.37arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)152272835342072050Rat
1578646Bmd18Bone mineral density QTL 185.2femur mineral mass (VT:0010011)trabecular volumetric bone mineral density (CMO:0001729)1525285835104695021Rat
2324620Coatc3Coat color QTL 3coat/hair pigmentation trait (VT:0010463)pigmented coat/hair area to total coat/hair area ratio (CMO:0001810)152233635152597086Rat
1578647Bmd17Bone mineral density QTL 174femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)1525285835104695021Rat
61424Scl1Serum cholesterol level QTL 17.70.001blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)151915576287086765Rat
10401805Kidm51Kidney mass QTL 51kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)15278592347785923Rat
1354657Despr13Despair related QTL 130.0022locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)15132342855Rat
2317750Glom26Glomerulus QTL 264.3urine protein amount (VT:0005160)urine protein level (CMO:0000591)151492659471614418Rat
631550Bw7Body weight QTL 73.6body mass (VT:0001259)body weight (CMO:0000012)152233635167336351Rat
1578660Bss19Bone structure and strength QTL 194.3femur morphology trait (VT:0000559)bone trabecular cross-sectional area (CMO:0002311)1525285835104695021Rat
5685002Bss103Bone structure and strength QTL 1032.8tibia strength trait (VT:1000284)tibia total energy absorbed before break (CMO:0001736)151691152132439851Rat

Markers in Region
D15Rat6  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21528,030,665 - 28,030,847 (+)MAPPERmRatBN7.2
Rnor_6.01533,219,101 - 33,219,282NCBIRnor6.0
Rnor_5.01537,103,190 - 37,103,371UniSTSRnor5.0
RGSC_v3.41532,638,412 - 32,638,778RGDRGSC3.4
RGSC_v3.41532,638,506 - 32,638,707UniSTSRGSC3.4
RGSC_v3.11532,654,112 - 32,654,478RGD
RH 2.0 Map15174.3RGD
SHRSP x BN Map1525.6198RGD
Cytogenetic Map15p13UniSTS
D15Rat85  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr81532,000,633 - 32,000,868 (+)Marker Load Pipeline
mRatBN7.21528,030,612 - 28,030,847 (+)MAPPERmRatBN7.2
Rnor_6.01533,219,048 - 33,219,282NCBIRnor6.0
Rnor_5.01537,103,137 - 37,103,371UniSTSRnor5.0
RGSC_v3.41532,638,452 - 32,638,707RGDRGSC3.4
RGSC_v3.41532,638,453 - 32,638,707UniSTSRGSC3.4
Celera1527,611,261 - 27,611,582UniSTS
RGSC_v3.11532,654,153 - 32,654,407RGD
RH 3.4 Map15201.0UniSTS
RH 3.4 Map15201.0RGD
RH 2.0 Map15173.8RGD
SHRSP x BN Map1525.6598RGD
Cytogenetic Map15p13UniSTS
RH131975  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21528,019,869 - 28,020,077 (+)MAPPERmRatBN7.2
mRatBN7.25139,221,340 - 139,221,548 (-)MAPPERmRatBN7.2
mRatBN7.25139,221,340 - 139,221,548 (+)MAPPERmRatBN7.2
mRatBN7.21528,019,869 - 28,020,077 (-)MAPPERmRatBN7.2
Rnor_6.01533,208,305 - 33,208,512NCBIRnor6.0
Rnor_6.05144,953,185 - 144,953,392NCBIRnor6.0
Rnor_5.05148,723,437 - 148,723,644UniSTSRnor5.0
Rnor_5.01537,092,394 - 37,092,601UniSTSRnor5.0
RGSC_v3.45146,342,495 - 146,342,702UniSTSRGSC3.4
RGSC_v3.41532,627,728 - 32,627,935UniSTSRGSC3.4
Celera1527,595,990 - 27,596,197UniSTS
Celera5137,716,397 - 137,716,604UniSTS
Cytogenetic Map15p13UniSTS
Cytogenetic Map5q36UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 162 91 90 59 49 59 6 313 149 11 141 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000017753   ⟹   ENSRNOP00000017753
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1531,989,799 - 32,000,042 (-)Ensembl
mRatBN7.2 Ensembl1528,019,778 - 28,030,021 (-)Ensembl
Rnor_6.0 Ensembl1533,208,216 - 33,218,456 (-)Ensembl
RefSeq Acc Id: NM_053503   ⟹   NP_445955
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81531,989,796 - 32,000,042 (-)NCBI
mRatBN7.21528,019,775 - 28,030,021 (-)NCBI
Rnor_6.01533,208,210 - 33,218,456 (-)NCBI
Rnor_5.01537,092,299 - 37,103,304 (-)NCBI
RGSC_v3.41532,627,633 - 32,637,861 (-)RGD
Celera1527,595,895 - 27,610,669 (-)RGD
Sequence:
RefSeq Acc Id: XM_063274732   ⟹   XP_063130802
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81531,989,796 - 31,995,461 (-)NCBI
Protein Sequences
Protein RefSeqs NP_445955 (Get FASTA)   NCBI Sequence Viewer  
  XP_063130802 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAH85802 (Get FASTA)   NCBI Sequence Viewer  
  CAC28536 (Get FASTA)   NCBI Sequence Viewer  
  EDM14178 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000017753
  ENSRNOP00000017753.3
GenBank Protein Q5U2Z2 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_445955   ⟸   NM_053503
- UniProtKB: Q99ND4 (UniProtKB/Swiss-Prot),   Q5U2Z2 (UniProtKB/Swiss-Prot),   A6KGU9 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000017753   ⟸   ENSRNOT00000017753
RefSeq Acc Id: XP_063130802   ⟸   XM_063274732
- Peptide Label: isoform X1
Protein Domains
LIM zinc-binding

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q5U2Z2-F1-model_v2 AlphaFold Q5U2Z2 1-548 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13699654
Promoter ID:EPDNEW_R10177
Type:single initiation site
Name:Ajuba_1
Description:ajuba LIM protein
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01533,218,422 - 33,218,482EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:620407 AgrOrtholog
BioCyc Gene G2FUF-13794 BioCyc
Ensembl Genes ENSRNOG00000012791 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000017753 ENTREZGENE
  ENSRNOT00000017753.6 UniProtKB/Swiss-Prot
Gene3D-CATH Cysteine Rich Protein UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:7110970 IMAGE-MGC_LOAD
InterPro Ajuba-like UniProtKB/Swiss-Prot
  Ajuba-like_LIM1 UniProtKB/Swiss-Prot
  Ajuba-like_LIM2 UniProtKB/Swiss-Prot
  Ajuba-like_LIM3 UniProtKB/Swiss-Prot
  Znf_LIM UniProtKB/Swiss-Prot
KEGG Report rno:85265 UniProtKB/Swiss-Prot
MGC_CLONE MGC:93830 IMAGE-MGC_LOAD
NCBI Gene 85265 ENTREZGENE
PANTHER LIM DOMAIN-CONTAINING PROTEIN AJUBA UniProtKB/Swiss-Prot
  LIM DOMAIN-CONTAINING PROTEIN JUB UniProtKB/Swiss-Prot
Pfam LIM UniProtKB/Swiss-Prot
PhenoGen Ajuba PhenoGen
PROSITE LIM_DOMAIN_1 UniProtKB/Swiss-Prot
  LIM_DOMAIN_2 UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000012791 RatGTEx
SMART LIM UniProtKB/Swiss-Prot
Superfamily-SCOP Glucocorticoid receptor-like (DNA-binding domain) UniProtKB/Swiss-Prot
UniProt A6KGU9 ENTREZGENE, UniProtKB/TrEMBL
  AJUBA_RAT UniProtKB/Swiss-Prot, ENTREZGENE
  Q99ND4 ENTREZGENE
UniProt Secondary Q99ND4 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2011-12-06 Ajuba  ajuba LIM protein  Jub  jub, ajuba homolog (Xenopus laevis)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-10-17 Jub  jub, ajuba homolog (Xenopus laevis)  Jub  ajuba  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-02-25 Jub  ajuba  Jub  ajuba homolog (Xenopus laevis)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-01-20 Jub  ajuba homolog (Xenopus laevis)    Ajuba protein  Name updated 1299863 APPROVED
2002-08-07 Jub  Ajuba protein      Symbol and Name status set to provisional 70820 PROVISIONAL

RGD Curation Notes
Note Type Note Reference
gene_cellular_localization localizes to the cytoplasm and translocates to the plasma membrane