Agps (alkylglycerone phosphate synthase) - Rat Genome Database

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Pathways
Gene: Agps (alkylglycerone phosphate synthase) Rattus norvegicus
Analyze
Symbol: Agps
Name: alkylglycerone phosphate synthase
RGD ID: 620364
Description: Enables alkylglycerone-phosphate synthase activity. Predicted to be involved in ether lipid biosynthetic process. Located in peroxisome. Human ortholog(s) of this gene implicated in rhizomelic chondrodysplasia punctata and rhizomelic chondrodysplasia punctata type 3. Orthologous to human AGPS (alkylglycerone phosphate synthase); PARTICIPATES IN plasmalogen biosynthetic pathway; plasmalogen metabolic pathway; ether lipid metabolic pathway; INTERACTS WITH (+)-schisandrin B; 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: Adap-s; Adps; Ads; alkyl-DHAP synthase; alkyl-dihydroxyacetonephosphate synthase; alkyl-dihydroxyacetonephosphate synthase precursor; alkyldihydroxyacetone phosphate synthase; alkyldihydroxyacetonephosphate synthase, peroxisomal; alkylglycerone phosphate synthase-like; alkylglycerone-phosphate synthase; LOC100360503
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8381,154,599 - 81,253,099 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl381,154,604 - 81,258,277 (+)EnsemblGRCr8
mRatBN7.2360,747,323 - 60,845,831 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl360,747,323 - 60,845,830 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx364,120,994 - 64,219,055 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0372,704,658 - 72,802,714 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0370,471,616 - 70,569,962 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0362,648,352 - 62,749,250 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl362,648,447 - 62,749,153 (+)Ensemblrn6Rnor6.0
Rnor_5.0369,193,349 - 69,296,169 (+)NCBIRnor_5.0Rnor_5.0rn5
Celera360,248,210 - 60,345,456 (+)NCBICelera
RGSC_v3.1358,425,040 - 58,444,100 (+)NCBI
Cytogenetic Map3q23NCBI
JBrowse:




Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-schisandrin B  (EXP)
(-)-epigallocatechin 3-gallate  (ISO)
1,1-dichloroethene  (ISO)
17alpha-ethynylestradiol  (EXP)
17beta-hydroxy-5alpha-androstan-3-one  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4-dinitrotoluene  (EXP)
2-methylcholine  (ISO)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
4,4'-sulfonyldiphenol  (ISO)
aflatoxin B1  (ISO)
all-trans-retinoic acid  (ISO)
amphetamine  (EXP)
arsenous acid  (ISO)
atrazine  (ISO)
benzatropine  (ISO)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
beta-lapachone  (ISO)
bisphenol A  (EXP,ISO)
bisphenol AF  (ISO)
Bisphenol B  (ISO)
bisphenol F  (ISO)
Butylbenzyl phthalate  (EXP)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
carnosic acid  (ISO)
CGP 52608  (ISO)
chlordecone  (ISO)
chlorpyrifos  (ISO)
cobalt dichloride  (ISO)
copper atom  (ISO)
copper(0)  (ISO)
copper(II) sulfate  (ISO)
Cuprizon  (ISO)
cyclosporin A  (ISO)
dexamethasone  (ISO)
diarsenic trioxide  (ISO)
dicrotophos  (ISO)
diquat  (ISO)
ethyl methanesulfonate  (ISO)
fipronil  (EXP)
flavonoids  (EXP)
formaldehyde  (ISO)
FR900359  (ISO)
furan  (EXP)
haloperidol  (ISO)
indometacin  (EXP,ISO)
ivermectin  (ISO)
ketoconazole  (ISO)
methyl methanesulfonate  (ISO)
methylmercury chloride  (ISO)
nickel atom  (ISO)
paracetamol  (ISO)
phenobarbital  (ISO)
pirinixic acid  (ISO)
potassium chromate  (ISO)
resveratrol  (ISO)
Salinomycin  (ISO)
sodium arsenate  (ISO)
sodium arsenite  (ISO)
tamibarotene  (ISO)
temozolomide  (ISO)
tetrachloromethane  (EXP)
thioacetamide  (EXP)
titanium dioxide  (ISO)
trimellitic anhydride  (ISO)
triphenyl phosphate  (ISO)
Triptolide  (EXP)
valproic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
peroxisomal membrane  (IEA)
peroxisome  (IBA,IDA,IEA,ISO,TAS)

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Alkyl-dihydroxyacetonephosphate synthase. Fate in peroxisome biogenesis disorders and identification of the point mutation underlying a single enzyme deficiency. de Vet EC, etal., J Biol Chem 1998 Apr 24;273(17):10296-301.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
4. Kinetic studies of alkyl-dihydroxyacetone-phosphate (alkyl-glycerone-phosphate) synthase in peroxisomes of rat liver. Gunawan J, etal., Biol Chem Hoppe Seyler 1990 Apr;371(4):339-44.
5. Proteomic analysis of rat liver peroxisome: presence of peroxisome-specific isozyme of Lon protease. Kikuchi M, etal., J Biol Chem. 2004 Jan 2;279(1):421-8. Epub 2003 Oct 15.
6. Activities of enzymes involved in the metabolism of ether-linked lipids in normal and neoplastic tissues of rat. Lee TC, etal., Biochim Biophys Acta. 1980 Aug 11;619(2):420-3.
7. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
8. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
9. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
10. SMPDB Annotation Import Pipeline Pipeline to import SMPDB annotations from SMPDB into RGD
11. GOA pipeline RGD automated data pipeline
12. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
13. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
14. PPAR gamma activators induce growth arrest and process extension in B12 oligodendrocyte-like cells and terminal differentiation of cultured oligodendrocytes. Roth AD, etal., J Neurosci Res. 2003 May 15;72(4):425-35.
15. Dihydroxyacetone phosphate acyltransferase and alkyldihydroxyacetone phosphate synthase activities in rat liver subcellular fractions and human skin fibroblasts. Singh H, etal., Arch Biochem Biophys. 1989 Feb 1;268(2):676-86.
16. Ether lipid synthesis: purification and identification of alkyl dihydroxyacetone phosphate synthase from guinea-pig liver. Zomer AW, etal., Biochim Biophys Acta. 1993 Oct 13;1170(2):189-96. doi: 10.1016/0005-2760(93)90070-p.
Additional References at PubMed
PMID:8889548   PMID:10415121   PMID:11369596   PMID:18614015   PMID:19946888   PMID:20833797   PMID:21525035  


Genomics

Comparative Map Data
Agps
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8381,154,599 - 81,253,099 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl381,154,604 - 81,258,277 (+)EnsemblGRCr8
mRatBN7.2360,747,323 - 60,845,831 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl360,747,323 - 60,845,830 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx364,120,994 - 64,219,055 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0372,704,658 - 72,802,714 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0370,471,616 - 70,569,962 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0362,648,352 - 62,749,250 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl362,648,447 - 62,749,153 (+)Ensemblrn6Rnor6.0
Rnor_5.0369,193,349 - 69,296,169 (+)NCBIRnor_5.0Rnor_5.0rn5
Celera360,248,210 - 60,345,456 (+)NCBICelera
RGSC_v3.1358,425,040 - 58,444,100 (+)NCBI
Cytogenetic Map3q23NCBI
AGPS
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382177,392,773 - 177,543,834 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2177,392,576 - 177,567,024 (+)Ensemblhg38GRCh38
GRCh372178,257,501 - 178,408,562 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362177,965,731 - 178,112,411 (+)NCBIBuild 36Build 36hg18NCBI36
Build 342178,083,009 - 178,228,512NCBI
Celera2171,860,003 - 172,011,409 (+)NCBICelera
Cytogenetic Map2q31.2NCBI
HuRef2170,128,203 - 170,279,631 (+)NCBIHuRef
CHM1_12178,262,812 - 178,413,489 (+)NCBICHM1_1
T2T-CHM13v2.02177,875,047 - 178,026,109 (+)NCBIT2T-CHM13v2.0
Agps
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39275,662,477 - 75,761,694 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl275,662,521 - 75,761,694 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm38275,832,177 - 75,931,350 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl275,832,177 - 75,931,350 (+)Ensemblmm10GRCm38
MGSCv37275,670,234 - 75,769,407 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36275,633,031 - 75,730,489 (+)NCBIMGSCv36mm8
Celera277,493,849 - 77,593,052 (+)NCBICelera
Cytogenetic Map2C3NCBI
cM Map244.77NCBI
Agps
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540319,257,501 - 19,381,901 (-)Ensembl
ChiLan1.0NW_00495540319,253,784 - 19,381,883 (-)NCBIChiLan1.0ChiLan1.0
AGPS
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21380,058,687 - 80,208,144 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12B80,073,679 - 80,223,118 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02B64,671,136 - 64,823,956 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12B182,375,149 - 182,526,192 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2B182,375,149 - 182,520,557 (+)EnsemblpanPan2panpan1.1
AGPS
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13621,131,616 - 21,264,615 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3621,131,641 - 21,329,467 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha3621,149,863 - 21,284,172 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.03621,274,757 - 21,409,268 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3621,276,105 - 21,474,081 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13621,345,042 - 21,479,391 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03621,346,803 - 21,481,415 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03621,462,141 - 21,596,527 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Agps
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405303138,188,897 - 138,319,862 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365096,742,673 - 6,868,401 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049365096,742,800 - 6,872,045 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
AGPS
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1583,146,002 - 83,391,984 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.11583,146,063 - 83,285,905 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21592,609,561 - 92,727,304 (+)NCBISscrofa10.2Sscrofa10.2susScr3
AGPS
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11062,943,914 - 63,101,644 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1062,946,695 - 63,096,044 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_023666040136,479,515 - 136,640,249 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Agps
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462478714,513,082 - 14,656,632 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462478714,517,552 - 14,661,138 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Agps
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v1553,179,426 - 53,279,181 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Agps
556 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:82
Count of miRNA genes:71
Interacting mature miRNAs:73
Transcripts:ENSRNOT00000002111
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1300178Hrtrt4Heart rate QTL 43.74heart pumping trait (VT:2000009)heart rate (CMO:0000002)351490129111359995Rat
61377Edpm3Estrogen-dependent pituitary mass QTL 37.050.038pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)373592611110333156Rat
1358293Bw38Body weight QTL 3860.0000031body mass (VT:0001259)body weight (CMO:0000012)374364268119364268Rat
1582238Bw68Body weight QTL 683.20.0064body mass (VT:0001259)body weight (CMO:0000012)373592512136118980Rat
1331795Rf30Renal function QTL 303.708urine potassium amount (VT:0010539)urine potassium level (CMO:0000128)35986366387321459Rat
1582239Epfw1Epididymal fat weight QTL 14.50.0006epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)373592512136118980Rat
70216Cm14Cardiac mass QTL 142.1heart mass (VT:0007028)heart wet weight (CMO:0000069)351581665184004958Rat
1354589Bw31Body weight QTL 313.3body mass (VT:0001259)body weight (CMO:0000012)35365182698651826Rat
2303593Gluco46Glucose level QTL 463blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)34887661993876619Rat
1354590Despr11Despair related QTL 110.000031locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)34887661993876619Rat
2298542Neuinf11Neuroinflammation QTL 113.9nervous system integrity trait (VT:0010566)spinal cord complement component 1, q subcomponent, B chain mRNA level (CMO:0002126)33540319997383526Rat
2292591Esta4Estrogen-induced thymic atrophy QTL 4thymus mass (VT:0004954)thymus wet weight (CMO:0000855)367641776167835660Rat
1358362Srcrt2Stress Responsive Cort QTL 22.78blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)358601291153936591Rat
631832Sach1Saccharin preference QTL 12.70.02consumption behavior trait (VT:0002069)calculated saccharin drink intake volume (CMO:0001600)34790417292904172Rat
737818Hcar12Hepatocarcinoma resistance QTL 122.6liver integrity trait (VT:0010547)volume of individual liver tumorous lesion (CMO:0001078)349872657138829559Rat
1582218Bw74Body weight QTL 743.90.0021body mass (VT:0001259)body weight (CMO:0000012)373592512136118980Rat
1331777Bw24Body weight QTL 243.503body mass (VT:0001259)body weight (CMO:0000012)35986366387321459Rat
631647Bp122Blood pressure QTL 1226.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)35109256196092561Rat
1300169Bp177Blood pressure QTL 1772.96arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)33642511681425116Rat
9590286Uminl1Urine mineral level QTL 13.50.001urine mineral amount (VT:0015086)urine electrolyte level (CMO:0000593)34865774493657744Rat
724523Tsu1Thymus enlargement suppressive QTL 13.84thymus mass (VT:0004954)thymus weight to body weight ratio (CMO:0000612)370845569136091483Rat
4889966Bss95Bone structure and strength QTL 954.4tibia area (VT:1000281)tibia-fibula cross-sectional area (CMO:0001718)33779691982796919Rat
8662816Vetf4Vascular elastic tissue fragility QTL 44renal artery integrity trait (VT:0010642)number of ruptures of the internal elastic lamina of the renal arteries (CMO:0002563)379649560177741895Rat
2302276Bw82Body weight QTL 824.32body mass (VT:0001259)body weight (CMO:0000012)35986366383358329Rat
2292613Ept16Estrogen-induced pituitary tumorigenesis QTL 168.3pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)367641995130815812Rat
738019Anxrr10Anxiety related response QTL 103.9exploratory behavior trait (VT:0010471)number of entries into a discrete space in an experimental apparatus (CMO:0000960)358925062103925062Rat
631841Niddm39Non-insulin dependent diabetes mellitus QTL 393.36blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)370311536115311536Rat
9590136Scort3Serum corticosterone level QTL 323.370.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)34865774493657744Rat
61419Cia11Collagen induced arthritis QTL 115.6joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)35076614595766145Rat
61356Bp37Blood pressure QTL 373blood pressure trait (VT:0000183)systolic blood pressure (CMO:0000004)35109256196092561Rat
1358905Hrtrt17Heart rate QTL 175.90.000014heart pumping trait (VT:2000009)heart rate (CMO:0000002)336721849110333156Rat
1558650Cm48Cardiac mass QTL 4840.0001heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)35076614595766145Rat
8694196Abfw2Abdominal fat weight QTL 216.580.001visceral adipose mass (VT:0010063)abdominal fat pad weight to body weight ratio (CMO:0000095)34865774493657744Rat
1358885Bp251Blood pressure QTL 2513.8arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)31141509147Rat
1354597Kidm13Kidney mass QTL 132.9kidney mass (VT:0002707)right kidney wet weight (CMO:0000082)342158111124558371Rat
1582249Bw77Body weight QTL 773.20.0025epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)37359251285062403Rat
2325840Bp345Blood pressure QTL 3450.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)33870893183708931Rat
8552950Pigfal12Plasma insulin-like growth factor 1 level QTL 127.3blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)34865774493657744Rat
631676Cm8Cardiac mass QTL 87.030.0001aorta mass (VT:0002845)aorta weight (CMO:0000076)33736373482363734Rat
8694386Bw159Body weight QTL 1594.520.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)34865774493657744Rat
1354604Bw36Body weight QTL 362.9body mass (VT:0001259)body weight (CMO:0000012)342158111124558371Rat
1358888Bp264Blood pressure QTL 2644.43arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)35675975141509147Rat
1358186Ept2Estrogen-induced pituitary tumorigenesis QTL 28.3pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)367641995130815812Rat

Markers in Region
BF403642  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2360,746,079 - 60,746,284 (+)MAPPERmRatBN7.2
Rnor_6.0362,647,109 - 62,647,313NCBIRnor6.0
Rnor_5.0369,192,106 - 69,192,310UniSTSRnor5.0
RGSC_v3.4358,527,331 - 58,527,535UniSTSRGSC3.4
Celera360,246,966 - 60,247,170UniSTS
Cytogenetic Map3q23UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 163 91 90 59 92 59 6 355 192 11 142 80 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000002111   ⟹   ENSRNOP00000002111
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl381,154,604 - 81,258,277 (+)Ensembl
mRatBN7.2 Ensembl360,747,323 - 60,845,830 (+)Ensembl
Rnor_6.0 Ensembl362,648,447 - 62,749,153 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000093964   ⟹   ENSRNOP00000095474
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl381,154,604 - 81,258,277 (+)Ensembl
mRatBN7.2 Ensembl360,763,713 - 60,845,830 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000096806   ⟹   ENSRNOP00000079560
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl381,154,604 - 81,258,277 (+)Ensembl
mRatBN7.2 Ensembl360,747,323 - 60,845,830 (+)Ensembl
RefSeq Acc Id: NM_053350   ⟹   NP_445802
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8381,154,599 - 81,253,099 (+)NCBI
mRatBN7.2360,747,323 - 60,845,831 (+)NCBI
Rnor_6.0362,648,352 - 62,749,250 (+)NCBI
Rnor_5.0369,193,349 - 69,296,169 (+)NCBI
Celera360,248,210 - 60,345,456 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_445802 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAG43235 (Get FASTA)   NCBI Sequence Viewer  
  CAB40909 (Get FASTA)   NCBI Sequence Viewer  
  EDL79213 (Get FASTA)   NCBI Sequence Viewer  
  EDL79214 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000079560
GenBank Protein Q9EQR2 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_445802   ⟸   NM_053350
- UniProtKB: A0A8I5ZN98 (UniProtKB/TrEMBL),   A6HMG2 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000002111   ⟸   ENSRNOT00000002111
Ensembl Acc Id: ENSRNOP00000095474   ⟸   ENSRNOT00000093964
Ensembl Acc Id: ENSRNOP00000079560   ⟸   ENSRNOT00000096806
Protein Domains
FAD-binding PCMH-type

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q9EQR2-F1-model_v2 AlphaFold Q9EQR2 1-644 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13692154
Promoter ID:EPDNEW_R2679
Type:initiation region
Name:Agps_1
Description:alkylglycerone phosphate synthase
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0362,648,430 - 62,648,490EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:620364 AgrOrtholog
BioCyc Gene G2FUF-49298 BioCyc
BioCyc Pathway PWY-7782 [plasmalogen biosynthesis] BioCyc
BioCyc Pathway Image PWY-7782 BioCyc
Ensembl Genes ENSRNOG00000001547 Ensembl, ENTREZGENE
Ensembl Transcript ENSRNOT00000096806 ENTREZGENE
Gene3D-CATH 3.30.160.650 UniProtKB/Swiss-Prot
  3.30.300.330 UniProtKB/Swiss-Prot
  3.30.43.10 UniProtKB/Swiss-Prot
  3.30.465.10 UniProtKB/Swiss-Prot
  3.30.70.3450 UniProtKB/Swiss-Prot
  Vanillyl-alcohol Oxidase, Chain A, domain 4 UniProtKB/Swiss-Prot
InterPro Alkyl-DHAP_Synthase UniProtKB/Swiss-Prot
  FAD-bd_PCMH UniProtKB/Swiss-Prot
  FAD-bd_PCMH-like_sf UniProtKB/Swiss-Prot
  FAD-bd_PCMH_sub1 UniProtKB/Swiss-Prot
  FAD-bd_PCMH_sub2 UniProtKB/Swiss-Prot
  FAD-linked_Oxase-like_C UniProtKB/Swiss-Prot
  FAD-linked_oxidase_C UniProtKB/Swiss-Prot
  Oxid_FAD_bind_N UniProtKB/Swiss-Prot
  Vanillyl_alc_oxidase_C-sub2 UniProtKB/Swiss-Prot
KEGG Report rno:84114 UniProtKB/Swiss-Prot
NCBI Gene 84114 ENTREZGENE
PANTHER ALKYLDIHYDROXYACETONEPHOSPHATE SYNTHASE, PEROXISOMAL UniProtKB/Swiss-Prot
  PTHR46568 UniProtKB/Swiss-Prot
Pfam FAD-oxidase_C UniProtKB/Swiss-Prot
  FAD_binding_4 UniProtKB/Swiss-Prot
PhenoGen Agps PhenoGen
PROSITE FAD_PCMH UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000001547 RatGTEx
Superfamily-SCOP SSF55103 UniProtKB/Swiss-Prot
  SSF56176 UniProtKB/Swiss-Prot
UniProt A0A8I5ZN98 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6GLM9_RAT UniProtKB/TrEMBL
  A6HMG2 ENTREZGENE, UniProtKB/TrEMBL
  A6HMG3_RAT UniProtKB/TrEMBL
  ADAS_RAT UniProtKB/Swiss-Prot
  F1M9Q8_RAT UniProtKB/TrEMBL
  Q9EQR2 ENTREZGENE
  Q9WUW6_RAT UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2013-04-17 Agps  alkylglycerone phosphate synthase  LOC100360503  alkylglycerone phosphate synthase-like  Data merged from RGD:2321954 737654 PROVISIONAL
2010-05-06 LOC100360503  alkylglycerone phosphate synthase-like      Symbol and Name status set to provisional 70820 PROVISIONAL
2005-01-20 Agps  alkylglycerone phosphate synthase    alkyl-dihydroxyacetonephosphate synthase precursor  Name updated 1299863 APPROVED
2002-08-07 Agps  alkyl-dihydroxyacetonephosphate synthase precursor      Symbol and Name status set to provisional 70820 PROVISIONAL