Abcf1 (ATP binding cassette subfamily F member 1) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)
Gene: Abcf1 (ATP binding cassette subfamily F member 1) Rattus norvegicus
Analyze
Symbol: Abcf1
Name: ATP binding cassette subfamily F member 1
RGD ID: 620286
Description: Predicted to enable ATP binding activity; ribosome binding activity; and translation activator activity. Predicted to be involved in positive regulation of translation and translational initiation. Located in ribosome. Orthologous to human ABCF1 (ATP binding cassette subfamily F member 1); INTERACTS WITH 17alpha-ethynylestradiol; 2,4-dinitrotoluene; 2,6-dinitrotoluene.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: Abc50; ATP-binding cassette 50; ATP-binding cassette sub-family F member 1; ATP-binding cassette, sub-family F (GCN20), member 1; ATP-binding cassette, subfamily F (GCN20), member 1
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8202,807,315 - 2,820,240 (+)NCBIGRCr8
mRatBN7.2202,802,519 - 2,815,433 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl202,802,488 - 2,815,433 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx202,854,007 - 2,867,015 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0202,858,976 - 2,871,984 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0202,885,513 - 2,898,407 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0203,309,914 - 3,322,828 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl203,309,899 - 3,322,825 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0205,407,475 - 5,420,356 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4202,953,604 - 2,962,140 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1202,953,831 - 2,962,361 (+)NCBI
Celera20228,398 - 241,279 (+)NCBICelera
Cytogenetic Map20p12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,2-dimethylhydrazine  (ISO)
1-nitropyrene  (ISO)
17alpha-ethynylestradiol  (EXP,ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (ISO)
2,4-dinitrotoluene  (EXP)
2,6-dinitrotoluene  (EXP)
2-methylcholine  (ISO)
3-chloropropane-1,2-diol  (EXP)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
4,4'-sulfonyldiphenol  (ISO)
4-amino-2,6-dinitrotoluene  (EXP)
acrylamide  (ISO)
aflatoxin B1  (ISO)
ammonium chloride  (EXP)
asperentin  (ISO)
atrazine  (ISO)
benzo[a]pyrene  (ISO)
bisphenol A  (EXP,ISO)
Bisphenol B  (ISO)
bisphenol F  (ISO)
Brevianamide A  (ISO)
buspirone  (EXP)
cadmium dichloride  (EXP)
caffeine  (ISO)
captan  (ISO)
carbamazepine  (ISO)
celecoxib  (ISO)
clobetasol  (ISO)
clofibrate  (ISO)
coumarin  (ISO)
coumestrol  (ISO)
CU-O LINKAGE  (ISO)
deguelin  (ISO)
deoxynivalenol  (ISO)
dexamethasone  (ISO)
Dibutyl phosphate  (ISO)
dibutyl phthalate  (ISO)
dicrotophos  (ISO)
disodium selenite  (ISO)
doxorubicin  (EXP)
endosulfan  (EXP)
Enterolactone  (ISO)
enzyme inhibitor  (ISO)
ethanol  (ISO)
flutamide  (EXP)
folic acid  (ISO)
folpet  (ISO)
FR900359  (ISO)
fulvestrant  (ISO)
gentamycin  (EXP)
hexadecanoic acid  (ISO)
indometacin  (ISO)
iron(2+) sulfate (anhydrous)  (ISO)
ivermectin  (ISO)
lead(0)  (ISO)
mycophenolic acid  (ISO)
mycotoxin  (ISO)
neoechinulin A  (ISO)
paracetamol  (ISO)
phenobarbital  (ISO)
potassium dichromate  (ISO)
resveratrol  (ISO)
rifampicin  (ISO)
rotenone  (EXP,ISO)
SB 431542  (ISO)
sodium arsenite  (ISO)
sodium dichromate  (ISO)
sodium fluoride  (ISO)
sterigmatocystin  (ISO)
tetrachloromethane  (EXP)
tetrahydropalmatine  (ISO)
TMC-120A  (ISO)
trichloroethene  (ISO)
trimellitic anhydride  (ISO)
triphenyl phosphate  (ISO)
troglitazone  (ISO)
tungsten  (ISO)
valproic acid  (ISO)
vinclozolin  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytoplasm  (IEA,ISO)
cytosol  (IEA,ISO)
nuclear envelope  (ISO,ISS)
nucleoplasm  (ISO,ISS)
ribosome  (IDA)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
4. GOA pipeline RGD automated data pipeline
5. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
6. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
7. ABC50 interacts with eukaryotic initiation factor 2 and associates with the ribosome in an ATP-dependent manner. Tyzack JK, etal., J Biol Chem 2000 Nov 3;275(44):34131-9.
Additional References at PubMed
PMID:12477932   PMID:15060004   PMID:17894550   PMID:19570978   PMID:19946888   PMID:22658674   PMID:22681889  


Genomics

Comparative Map Data
Abcf1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8202,807,315 - 2,820,240 (+)NCBIGRCr8
mRatBN7.2202,802,519 - 2,815,433 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl202,802,488 - 2,815,433 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx202,854,007 - 2,867,015 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0202,858,976 - 2,871,984 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0202,885,513 - 2,898,407 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0203,309,914 - 3,322,828 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl203,309,899 - 3,322,825 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0205,407,475 - 5,420,356 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4202,953,604 - 2,962,140 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1202,953,831 - 2,962,361 (+)NCBI
Celera20228,398 - 241,279 (+)NCBICelera
Cytogenetic Map20p12NCBI
ABCF1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38630,571,442 - 30,591,522 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl630,571,393 - 30,597,179 (+)EnsemblGRCh38hg38GRCh38
GRCh37630,539,219 - 30,559,299 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36630,647,149 - 30,667,288 (+)NCBINCBI36Build 36hg18NCBI36
Build 34630,647,148 - 30,667,067NCBI
Celera632,137,288 - 32,157,421 (+)NCBICelera
Cytogenetic Map6p21.33NCBI
HuRef630,339,240 - 30,359,384 (+)NCBIHuRef
CHM1_1630,541,266 - 30,561,417 (+)NCBICHM1_1
T2T-CHM13v2.0630,435,621 - 30,455,699 (+)NCBIT2T-CHM13v2.0
Abcf1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391736,267,711 - 36,280,642 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1736,267,711 - 36,280,653 (-)EnsemblGRCm39 Ensembl
GRCm381735,956,819 - 35,969,750 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1735,956,819 - 35,969,761 (-)EnsemblGRCm38mm10GRCm38
MGSCv371736,093,764 - 36,106,695 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361735,564,872 - 35,577,803 (-)NCBIMGSCv36mm8
Celera1739,470,344 - 39,483,322 (-)NCBICelera
Cytogenetic Map17B1NCBI
cM Map1718.8NCBI
Abcf1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955583600,398 - 606,820 (+)EnsemblChiLan1.0
ChiLan1.0NW_004955583600,381 - 607,211 (+)NCBIChiLan1.0ChiLan1.0
ABCF1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2545,129,737 - 45,149,503 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1641,092,823 - 41,112,558 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0630,314,216 - 30,333,912 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1631,184,720 - 31,203,789 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl631,184,831 - 31,203,059 (+)Ensemblpanpan1.1panPan2
ABCF1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.112396,947 - 410,951 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl12401,118 - 411,179 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha12527,719 - 549,348 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.012533,984 - 555,482 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl12540,881 - 555,480 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.112390,728 - 412,380 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.012460,059 - 481,701 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.012529,843 - 551,482 (+)NCBIUU_Cfam_GSD_1.0
Abcf1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494633,882,849 - 33,899,757 (+)NCBIHiC_Itri_2
SpeTri2.0NW_004936837248,133 - 265,016 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ABCF1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl723,126,283 - 23,145,006 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1723,126,255 - 23,144,030 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2726,795,857 - 26,813,632 (+)NCBISscrofa10.2Sscrofa10.2susScr3
LOC103221832
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11741,866,152 - 41,885,673 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1741,866,062 - 41,884,972 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604430,235,086 - 30,259,243 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Abcf1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475425,098,182 - 25,110,092 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462475425,097,202 - 25,110,164 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Abcf1
127 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:431
Count of miRNA genes:207
Interacting mature miRNAs:258
Transcripts:ENSRNOT00000001049
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
61472Aia1Adjuvant induced arthritis QTL 1180.001joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)2026463954597031Rat
2306850Pia40Pristane induced arthritis QTL 400.0001joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)2015279595304575Rat
1641915Colcr9Colorectal carcinoma resistance QTL 92.970.0024intestine integrity trait (VT:0010554)benign colorectal tumor number (CMO:0001795)20153065546530655Rat
7387283Uae44Urinary albumin excretion QTL 440.1712urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)20126123605Rat
7411668Foco32Food consumption QTL 3280.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)20136600972Rat
2305926Iddm37Insulin dependent diabetes mellitus QTL 376blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)20152784246527842Rat
1354642Despr15Despair related QTL 150.0027locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)20124159021Rat
1600382Edcs3Endometrial carcinoma susceptibility QTL33.50.003uterus morphology trait (VT:0001120)percentage of study population developing endometrioid carcinoma during a period of time (CMO:0001759)20125159026Rat
61448Ciaa1CIA Autoantibody QTL 1300.001blood autoantibody amount (VT:0003725)calculated serum anti-rat type 2 collagen autoantibody titer (CMO:0001281)2026463954597031Rat
8694189Bw153Body weight QTL 1533.130.001body mass (VT:0001259)body weight gain (CMO:0000420)20129191651Rat
724519Bp144Blood pressure QTL 1440.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)2013624629Rat
9590109Sffal8Serum free fatty acids level QTL 85.320.01blood free fatty acid amount (VT:0001553)plasma free fatty acids level (CMO:0000546)20129191651Rat
9590275Scort15Serum corticosterone level QTL 153.480.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)20129191651Rat
9589155Insul32Insulin level QTL 326.380.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)20129191651Rat
7411650Foco23Food consumption QTL 2320.70.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)20129191651Rat
2317851Alcrsp22Alcohol response QTL 223.20.05response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)20127339237Rat
1598816Memor12Memory QTL 122.4exploratory behavior trait (VT:0010471)average horizontal distance between subject and target during voluntary locomotion in an experimental apparatus (CMO:0002674)20260683647606836Rat
1641893Alcrsp7Alcohol response QTL 7response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)20127339237Rat
6893685Bw111Body weight QTL 1112.70.004body mass (VT:0001259)body weight (CMO:0000012)20132578807Rat
9590252Scort12Serum corticosterone level QTL 1220.460.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)20136600972Rat

Markers in Region
D20Yum34  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2202,807,242 - 2,807,408 (+)MAPPERmRatBN7.2
Rnor_6.0203,314,639 - 3,314,804NCBIRnor6.0
Rnor_5.0205,412,167 - 5,412,332UniSTSRnor5.0
RGSC_v3.4202,953,951 - 2,954,116UniSTSRGSC3.4
Celera20233,090 - 233,255UniSTS
Cytogenetic Map20p12UniSTS
RH128459  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2202,815,085 - 2,815,274 (+)MAPPERmRatBN7.2
Rnor_6.0203,322,481 - 3,322,669NCBIRnor6.0
Rnor_5.0205,420,009 - 5,420,197UniSTSRnor5.0
RGSC_v3.4202,961,792 - 2,961,981UniSTSRGSC3.4
Celera20240,932 - 241,120UniSTS
Cytogenetic Map20p12UniSTS
RH140082  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2202,810,160 - 2,810,370 (+)MAPPERmRatBN7.2
Rnor_6.0203,317,557 - 3,317,766NCBIRnor6.0
Rnor_5.0205,415,085 - 5,415,294UniSTSRnor5.0
RGSC_v3.4202,956,869 - 2,957,078UniSTSRGSC3.4
Celera20236,008 - 236,217UniSTS
Cytogenetic Map20p12UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31

Sequence


Ensembl Acc Id: ENSRNOT00000001049   ⟹   ENSRNOP00000001049
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl202,802,488 - 2,815,426 (+)Ensembl
Rnor_6.0 Ensembl203,309,899 - 3,322,825 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000078355
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl203,317,247 - 3,317,854 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000081403
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl203,309,947 - 3,316,427 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000095040   ⟹   ENSRNOP00000090778
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl202,802,584 - 2,815,433 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000113889   ⟹   ENSRNOP00000087295
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl202,802,560 - 2,815,426 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000119600   ⟹   ENSRNOP00000085554
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl202,802,551 - 2,815,427 (+)Ensembl
RefSeq Acc Id: NM_001109883   ⟹   NP_001103353
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8202,807,359 - 2,820,240 (+)NCBI
mRatBN7.2202,802,551 - 2,815,433 (+)NCBI
Rnor_6.0203,309,947 - 3,322,828 (+)NCBI
Rnor_5.0205,407,475 - 5,420,356 (+)NCBI
RGSC_v3.4202,953,604 - 2,962,140 (+)RGD
Celera20228,398 - 241,279 (+)RGD
Sequence:
RefSeq Acc Id: XM_017601783   ⟹   XP_017457272
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8202,807,315 - 2,820,237 (+)NCBI
mRatBN7.2202,802,519 - 2,815,430 (+)NCBI
Rnor_6.0203,309,914 - 3,322,825 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_001103353 (Get FASTA)   NCBI Sequence Viewer  
  XP_017457272 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAG23960 (Get FASTA)   NCBI Sequence Viewer  
  CAE84039 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000001049.7
  ENSRNOP00000085554.1
  ENSRNOP00000087295.1
  ENSRNOP00000090778.1
GenBank Protein Q6MG08 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_001103353   ⟸   NM_001109883
- UniProtKB: Q9ERQ2 (UniProtKB/Swiss-Prot),   Q6MG08 (UniProtKB/Swiss-Prot),   A0A8L2PZQ3 (UniProtKB/TrEMBL),   A6KT63 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017457272   ⟸   XM_017601783
- Peptide Label: isoform X1
- UniProtKB: A0A8L2PZQ3 (UniProtKB/TrEMBL),   A6KT63 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000001049   ⟸   ENSRNOT00000001049
Ensembl Acc Id: ENSRNOP00000085554   ⟸   ENSRNOT00000119600
Ensembl Acc Id: ENSRNOP00000090778   ⟸   ENSRNOT00000095040
Ensembl Acc Id: ENSRNOP00000087295   ⟸   ENSRNOT00000113889
Protein Domains
ABC transporter

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q6MG08-F1-model_v2 AlphaFold Q6MG08 1-839 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13701292
Promoter ID:EPDNEW_R11816
Type:initiation region
Name:Abcf1_1
Description:ATP binding cassette subfamily F member 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0203,309,943 - 3,310,003EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:620286 AgrOrtholog
BioCyc Gene G2FUF-4790 BioCyc
Ensembl Genes ENSRNOG00000000799 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000001049.8 UniProtKB/TrEMBL
  ENSRNOT00000095040.1 UniProtKB/TrEMBL
  ENSRNOT00000113889.1 UniProtKB/TrEMBL
  ENSRNOT00000119600.1 UniProtKB/TrEMBL
Gene3D-CATH 3.40.50.300 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7460278 IMAGE-MGC_LOAD
InterPro AAA+_ATPase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ABC_tran_Xtn UniProtKB/TrEMBL
  ABC_transporter-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ABC_transporter-like_CS UniProtKB/TrEMBL, UniProtKB/Swiss-Prot
  ABCF_EF3_subfamily UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  P-loop_NTPase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:85493 UniProtKB/Swiss-Prot
MGC_CLONE MGC:116244 IMAGE-MGC_LOAD
NCBI Gene 85493 ENTREZGENE
PANTHER ATP-BINDING CASSETTE SUB-FAMILY F MEMBER 1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ATP-BINDING TRANSPORT PROTEIN-RELATED UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam ABC_tran UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ABC_tran_Xtn UniProtKB/TrEMBL
PhenoGen Abcf1 PhenoGen
PROSITE ABC_TRANSPORTER_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ABC_TRANSPORTER_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RatGTEx ENSRNOG00000000799 RatGTEx
SMART AAA UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF52540 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A8I6A3L7_RAT UniProtKB/TrEMBL
  A0A8I6A7P9_RAT UniProtKB/TrEMBL
  A0A8I6AAT6_RAT UniProtKB/TrEMBL
  A0A8L2PZQ3 ENTREZGENE, UniProtKB/TrEMBL
  A6KT63 ENTREZGENE, UniProtKB/TrEMBL
  ABCF1_RAT UniProtKB/Swiss-Prot, ENTREZGENE
  Q9ERQ2 ENTREZGENE
UniProt Secondary Q9ERQ2 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-12-09 Abcf1  ATP binding cassette subfamily F member 1  Abcf1  ATP-binding cassette, subfamily F (GCN20), member 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2010-11-16 Abcf1  ATP-binding cassette, subfamily F (GCN20), member 1  Abcf1  ATP-binding cassette, sub-family F (GCN20), member 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2004-02-26 Abcf1  ATP-binding cassette, sub-family F (GCN20), member 1      Symbol and Name status set to approved 625702 APPROVED
2002-08-07 Abcf1  ATP-binding cassette, sub-family F (GCN20), member 1      Symbol and Name status set to provisional 70820 PROVISIONAL

RGD Curation Notes
Note Type Note Reference
gene_process no effect on eIF2 binding to GDP but greatly promoted the association of methionyl-tRNA with the factor 631944
gene_protein 110 kDa 631944