Dynlt1 (dynein light chain Tctex-type 1) - Rat Genome Database

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Gene: Dynlt1 (dynein light chain Tctex-type 1) Rattus norvegicus
Analyze
Symbol: Dynlt1
Name: dynein light chain Tctex-type 1
RGD ID: 620261
Description: Enables transmembrane transporter binding activity. Involved in several processes, including cardiac muscle cell apoptotic process; neuron projection development; and positive regulation of Rac protein signal transduction. Located in axonal growth cone; lamellipodium; and neuronal cell body. Orthologous to human DYNLT1 (dynein light chain Tctex-type 1); PARTICIPATES IN mitochondria transport pathway; INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: activator of G-protein signaling 2; AGS2; t-complex testis expressed 1; T-complex testis-specific protein 1 homolog; Tctex1
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8149,292,093 - 49,299,051 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl149,282,243 - 49,298,951 (-)EnsemblGRCr8
mRatBN7.2146,887,017 - 46,893,956 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl146,887,017 - 46,893,881 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx147,435,976 - 47,442,799 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0153,423,238 - 53,430,061 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0147,511,411 - 47,518,234 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0147,206,892 - 47,213,785 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl147,206,895 - 47,213,749 (-)Ensemblrn6Rnor6.0
Rnor_5.0148,510,103 - 48,516,996 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4141,097,174 - 41,103,997 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera142,574,662 - 42,581,485 (-)NCBICelera
RGSC_v3.1141,100,118 - 41,106,942 (-)NCBI
Cytogenetic Map1q11NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Cytoplasmic dynein. Allan VJ, Biochem Soc Trans. 2011 Oct;39(5):1169-78. doi: 10.1042/BST0391169.
2. The dynein light chain Tctex-1 has a dynein-independent role in actin remodeling during neurite outgrowth. Chuang JZ, etal., Dev Cell. 2005 Jul;9(1):75-86.
3. MAP4 mechanism that stabilizes mitochondrial permeability transition in hypoxia: microtubule enhancement and DYNLT1 interaction with VDAC1. Fang YD, etal., PLoS One. 2011;6(12):e28052. doi: 10.1371/journal.pone.0028052. Epub 2011 Dec 2.
4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
5. A tctex1-Ca2+ channel complex for selective surface expression of Ca2+ channels in neurons. Lai M, etal., Nat Neurosci. 2005 Apr;8(4):435-42. Epub 2005 Mar 13.
6. A direct interaction between cytoplasmic dynein and kinesin I may coordinate motor activity. Ligon LA, etal., J Biol Chem. 2004 Apr 30;279(18):19201-8. Epub 2004 Feb 24.
7. Sensory neuron proteins interact with the intracellular domains of sodium channel NaV1.8. Malik-Hall M, etal., Brain Res Mol Brain Res. 2003 Feb 20;110(2):298-304.
8. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
9. Interaction of Doc2 with tctex-1, a light chain of cytoplasmic dynein. Implication in dynein-dependent vesicle transport. Nagano F, etal., J Biol Chem 1998 Nov 13;273(46):30065-8.
10. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
11. GOA pipeline RGD automated data pipeline
12. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
13. Metabotropic glutamate receptor 5 knockout promotes motor and biochemical alterations in a mouse model of Huntington's disease. Ribeiro FM, etal., Hum Mol Genet. 2014 Apr 15;23(8):2030-42. doi: 10.1093/hmg/ddt598. Epub 2013 Nov 26.
14. Rhodopsin's carboxy-terminal cytoplasmic tail acts as a membrane receptor for cytoplasmic dynein by binding to the dynein light chain Tctex-1. Tai AW, etal., Cell. 1999 Jun 25;97(7):877-87.
15. Identification of hypertension-related genes through an integrated genomic-transcriptomic approach. Yagil C, etal., Circ Res. 2005 Apr 1;96(6):617-25. Epub 2005 Feb 24.
Additional References at PubMed
PMID:11157096   PMID:12477932   PMID:17965411   PMID:18647839   PMID:21262767   PMID:24170091   PMID:25205765  


Genomics

Comparative Map Data
Dynlt1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8149,292,093 - 49,299,051 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl149,282,243 - 49,298,951 (-)EnsemblGRCr8
mRatBN7.2146,887,017 - 46,893,956 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl146,887,017 - 46,893,881 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx147,435,976 - 47,442,799 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0153,423,238 - 53,430,061 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0147,511,411 - 47,518,234 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0147,206,892 - 47,213,785 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl147,206,895 - 47,213,749 (-)Ensemblrn6Rnor6.0
Rnor_5.0148,510,103 - 48,516,996 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4141,097,174 - 41,103,997 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera142,574,662 - 42,581,485 (-)NCBICelera
RGSC_v3.1141,100,118 - 41,106,942 (-)NCBI
Cytogenetic Map1q11NCBI
DYNLT1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh386158,636,474 - 158,644,743 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl6158,636,474 - 158,644,755 (-)Ensemblhg38GRCh38
GRCh376159,057,506 - 159,065,775 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 366158,977,497 - 158,985,728 (-)NCBIBuild 36Build 36hg18NCBI36
Build 346159,027,914 - 159,036,149NCBI
Celera6159,705,500 - 159,713,799 (-)NCBICelera
Cytogenetic Map6q25.3NCBI
HuRef6156,528,404 - 156,536,700 (-)NCBIHuRef
CHM1_16159,320,069 - 159,328,365 (-)NCBICHM1_1
T2T-CHM13v2.06159,881,698 - 159,889,969 (-)NCBIT2T-CHM13v2.0
Dynlt1b
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39176,697,511 - 6,703,695 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl176,697,511 - 6,703,695 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm38176,429,530 - 6,440,500 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl176,306,340 - 6,317,500 (-)Ensemblmm10GRCm38
GRCm38.p6 Ensembl176,430,112 - 6,436,296 (+)Ensemblmm10GRCm38
GRCm38.p6 Ensembl176,646,602 - 6,655,900 (-)Ensemblmm10GRCm38
GRCm38.p6 Ensembl176,601,671 - 6,609,774 (+)Ensemblmm10GRCm38
MGSCv37176,429,260 - 6,435,444 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36176,412,303 - 6,418,495 (-)NCBIMGSCv36mm8
Cytogenetic Map17A1NCBI
cM Map173.97NCBI
Dynlt1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554393,833,525 - 3,842,393 (+)Ensembl
ChiLan1.0NW_0049554393,833,525 - 3,842,393 (+)NCBIChiLan1.0ChiLan1.0
DYNLT1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v25178,744,093 - 178,752,350 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan16176,647,991 - 176,656,267 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v06156,530,068 - 156,538,346 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.16161,544,128 - 161,552,391 (-)NCBIPanPan1.1PanPan1.1panPan2
DYNLT1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1148,058,804 - 48,066,389 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl148,058,804 - 48,066,609 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha148,903,907 - 48,911,551 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0148,244,957 - 48,252,653 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl148,244,957 - 48,253,247 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1148,121,663 - 48,129,302 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0147,992,244 - 47,999,994 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0148,551,864 - 48,559,503 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Dynlt1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404946143,077,230 - 143,083,807 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493648910,329,223 - 10,335,782 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_00493648910,329,223 - 10,335,758 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
DYNLT1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl18,556,059 - 8,563,676 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.118,556,083 - 8,562,865 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2110,385,073 - 10,391,588 (-)NCBISscrofa10.2Sscrofa10.2susScr3
DYNLT1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11386,210,462 - 86,218,002 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1386,210,465 - 86,217,956 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366604058,592,316 - 58,599,872 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Dynlt1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624929968,823 - 976,414 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_004624929969,294 - 976,420 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Dynlt1
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v12192,495,030 - 192,501,999 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Dynlt1
57 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:27
Count of miRNA genes:26
Interacting mature miRNAs:26
Transcripts:ENSRNOT00000024656
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1331732Srn4Serum renin concentration QTL 44.467renin activity (VT:0005581)plasma renin activity level (CMO:0000116)14345783787558729Rat
631688Hcas2Hepatocarcinoma susceptibility QTL 230.0001liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)1774611852746118Rat
1357397Bw41Body weight QTL 414.190.0001body mass (VT:0001259)body weight (CMO:0000012)12940927974409279Rat
1358359Sradr1Stress Responsive Adrenal Weight QTL 14.74adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)139728272132889942Rat
4889929Bss87Bone structure and strength QTL 876.7tibia area (VT:1000281)tibia-fibula cortical bone endosteal cross-sectional area (CMO:0001722)14630261591302615Rat
1331792Rf29Renal function QTL 294.589urine potassium amount (VT:0010539)urine potassium level (CMO:0000128)14345783787558729Rat
2313062Bmd73Bone mineral density QTL 733.90.0001tibia mineral mass (VT:1000283)compact volumetric bone mineral density (CMO:0001730)14630261591302615Rat
8552900Pigfal1Plasma insulin-like growth factor 1 level QTL 17.4blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)14350995288509952Rat
1354643Foco2Food consumption QTL 27.170.0001eating behavior trait (VT:0001431)food intake rate (CMO:0000427)14212296887122968Rat
2313065Bss67Bone structure and strength QTL 673.10.0001tibia area (VT:1000281)tibia total energy absorbed before break (CMO:0001736)14630261591302615Rat
7421626Bp360Blood pressure QTL 3600.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1694102251941022Rat
1357401Bw43Body weight QTL 433.75body mass (VT:0001259)body weight (CMO:0000012)1690935351909353Rat
2313069Bss68Bone structure and strength QTL 682.90.0001tibia size trait (VT:0100001)tibia total energy absorbed before break (CMO:0001736)14630261591302615Rat
631494Bp95Blood pressure QTL 95400.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)11731537851816258Rat
70225Bp58Blood pressure QTL 583.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)134184556172281316Rat
2313075Bss66Bone structure and strength QTL 663.40.0001tibia length (VT:0004357)tibia length (CMO:0000450)14630261591302615Rat
5684998Bss101Bone structure and strength QTL 1013.6tibia strength trait (VT:1000284)tibia ultimate force (CMO:0001734)1690935351909353Rat
5684999Bss102Bone structure and strength QTL 1025.57e-07tibia strength trait (VT:1000284)tibia stiffness (CMO:0001735)1690935351909353Rat
10059597Bp377Blood pressure QTL 3773.420.025arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)134565911208798288Rat
1331778Rf28Renal function QTL 284.66urine potassium amount (VT:0010539)urine potassium excretion rate (CMO:0000761)14345783787558729Rat
2313077Bss69Bone structure and strength QTL 693.50.0001tibia strength trait (VT:1000284)bone polar moment of inertia (CMO:0001558)14630261591302615Rat
1578756Iddm22Insulin dependent diabetes mellitus QTL 222.7blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)12050832665508326Rat
1331785Rf27Renal function QTL 274.643urine sodium amount (VT:0006274)urine sodium level (CMO:0000129)13070837587558729Rat
631508Sald1Serum aldosterone level QTL 13.7blood aldosterone amount (VT:0005346)serum aldosterone level (CMO:0000487)11168446456684464Rat
1300172Bp172Blood pressure QTL 1723.56arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)13456572679565726Rat
4889451Eae29Experimental allergic encephalomyelitis QTL 295.51nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis severity score (CMO:0001419)1774612152746121Rat
1558642Prcr2Prostate cancer resistance QTL 24.3prostate integrity trait (VT:0010571)area of ventral prostate occupied by tumorous lesions to total ventral prostate area ratio (CMO:0000899)11037949255379492Rat
2313092Bmd72Bone mineral density QTL 722.50.0001tibia mineral mass (VT:1000283)total volumetric bone mineral density (CMO:0001728)14630261591302615Rat
2313097Bss70Bone structure and strength QTL 703.50.0001tibia strength trait (VT:1000284)tibia total energy absorbed before break (CMO:0001736)14630261591302615Rat
9589820Insglur3Insulin/glucose ratio QTL 310.750.001blood insulin amount (VT:0001560)calculated plasma insulin level (CMO:0002170)14350995288509952Rat
1354599Bw29Body weight QTL 293.460.001body mass (VT:0001259)body weight (CMO:0000012)14212296887122968Rat
2302038Pia31Pristane induced arthritis QTL 315.50.001blood autoantibody amount (VT:0003725)serum immunoglobulin M-type rheumatoid factor level relative to an arbitrary reference serum (CMO:0002111)11282049457820494Rat
4889919Bss86Bone structure and strength QTL 864.1tibia area (VT:1000281)tibia midshaft total cross-sectional area (CMO:0001715)14630261591302615Rat
8552948Pigfal11Plasma insulin-like growth factor 1 level QTL 114.7blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)14350995288509952Rat
634353Rends2Renal damage susceptibility QTL 20.05kidney blood vessel morphology trait (VT:0000530)organ lesion measurement (CMO:0000677)12065642065656420Rat

Markers in Region
D1Ztm7  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.0147,200,222 - 47,200,455NCBIRnor6.0
Rnor_5.0148,503,432 - 48,503,665UniSTSRnor5.0
RGSC_v3.4141,090,502 - 41,090,735UniSTSRGSC3.4
Celera142,567,990 - 42,568,223UniSTS
Cytogenetic Map1q11UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 165 91 90 59 92 59 6 356 192 11 144 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000024656   ⟹   ENSRNOP00000024656
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl149,292,095 - 49,298,949 (-)Ensembl
mRatBN7.2 Ensembl146,887,017 - 46,893,881 (-)Ensembl
Rnor_6.0 Ensembl147,206,895 - 47,213,749 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000107400   ⟹   ENSRNOP00000077983
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl149,292,094 - 49,298,728 (-)Ensembl
mRatBN7.2 Ensembl146,887,017 - 46,893,551 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000132321   ⟹   ENSRNOP00000101617
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl149,282,243 - 49,298,951 (-)Ensembl
RefSeq Acc Id: NM_031318   ⟹   NP_112608
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8149,292,094 - 49,298,917 (-)NCBI
mRatBN7.2146,887,018 - 46,893,841 (-)NCBI
Rnor_6.0147,206,894 - 47,213,717 (-)NCBI
Rnor_5.0148,510,103 - 48,516,996 (-)NCBI
RGSC_v3.4141,097,174 - 41,103,997 (-)RGD
Celera142,574,662 - 42,581,485 (-)RGD
Sequence:
RefSeq Acc Id: XM_006227901   ⟹   XP_006227963
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8149,292,093 - 49,299,051 (-)NCBI
mRatBN7.2146,887,017 - 46,893,956 (-)NCBI
Rnor_6.0147,206,892 - 47,213,785 (-)NCBI
Rnor_5.0148,510,103 - 48,516,996 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_112608 (Get FASTA)   NCBI Sequence Viewer  
  XP_006227963 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAI66879 (Get FASTA)   NCBI Sequence Viewer  
  BAA34532 (Get FASTA)   NCBI Sequence Viewer  
  CAC18728 (Get FASTA)   NCBI Sequence Viewer  
  EDL83717 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000024656
GenBank Protein Q9Z336 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_112608   ⟸   NM_031318
- UniProtKB: Q9Z336 (UniProtKB/Swiss-Prot),   B2RYR9 (UniProtKB/TrEMBL),   A0A8L2QD70 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006227963   ⟸   XM_006227901
- Peptide Label: isoform X1
- Sequence:
Ensembl Acc Id: ENSRNOP00000024656   ⟸   ENSRNOT00000024656
Ensembl Acc Id: ENSRNOP00000077983   ⟸   ENSRNOT00000107400
Ensembl Acc Id: ENSRNOP00000101617   ⟸   ENSRNOT00000132321

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q9Z336-F1-model_v2 AlphaFold Q9Z336 1-113 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13689607
Promoter ID:EPDNEW_R131
Type:initiation region
Name:Dynlt1_1
Description:dynein light chain Tctex-type 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0147,213,749 - 47,213,809EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:620261 AgrOrtholog
BioCyc Gene G2FUF-61616 BioCyc
Ensembl Genes ENSRNOG00000018207 Ensembl, ENTREZGENE
Ensembl Transcript ENSRNOT00000024656 ENTREZGENE
Gene3D-CATH 3.30.1140.40 UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:6919674 IMAGE-MGC_LOAD
InterPro Tctex-1-like UniProtKB/Swiss-Prot
  Tctex-1-like_sf UniProtKB/Swiss-Prot
KEGG Report rno:83462 UniProtKB/Swiss-Prot
MGC_CLONE MGC:188810 IMAGE-MGC_LOAD
NCBI Gene 83462 ENTREZGENE
PANTHER DYNEIN LIGHT CHAIN TCTEX-TYPE 1 UniProtKB/Swiss-Prot
  PTHR21255 UniProtKB/Swiss-Prot
Pfam Tctex-1 UniProtKB/Swiss-Prot
PhenoGen Dynlt1 PhenoGen
RatGTEx ENSRNOG00000018207 RatGTEx
UniProt A0A8I5Y6Y0_RAT UniProtKB/TrEMBL
  A0A8L2QD70 ENTREZGENE, UniProtKB/TrEMBL
  A0ABK0LJ87_RAT UniProtKB/TrEMBL
  B2RYR9 ENTREZGENE, UniProtKB/TrEMBL
  DYLT1_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-02-22 Dynlt1  dynein light chain Tctex-type 1  Tctex1  t-complex testis expressed 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2004-09-10 Tctex1  t-complex testis expressed 1      Symbol and Name status set to approved 1299863 APPROVED
2002-08-07 Tctex1  t-complex testis expressed 1      Symbol and Name status set to provisional 70820 PROVISIONAL

RGD Curation Notes
Note Type Note Reference
gene_disease identified as a possible hypertension gene 1559295
gene_expression ubiquitously expressed 634245
gene_physical_interaction binds to Doc2 634245
gene_protein 113 amino acids; 12.4 kDa 634245