DYNLT1 (dynein light chain Tctex-type 1) - Rat Genome Database

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Gene: DYNLT1 (dynein light chain Tctex-type 1) Canis lupus familiaris
Analyze
Symbol: DYNLT1
Name: dynein light chain Tctex-type 1
RGD ID: 12185672
Description: ENCODES a protein that exhibits G-protein beta-subunit binding (ortholog); GTP-dependent protein binding (ortholog); identical protein binding (ortholog); INVOLVED IN axon development (ortholog); cardiac muscle cell apoptotic process (ortholog); dendrite development (ortholog); PARTICIPATES IN mitochondria transport pathway; ASSOCIATED WITH 3-methylglutaconic aciduria with deafness, encephalopathy, and Leigh-like syndrome (ortholog); chromosome 6q24-q25 deletion syndrome (ortholog); primary ciliary dyskinesia 32 (ortholog); FOUND IN axonal growth cone (ortholog); cytoplasmic microtubule (ortholog); dynein complex (ortholog)
Type: protein-coding
RefSeq Status: MODEL
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1148,058,804 - 48,066,389 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl148,058,804 - 48,066,609 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha148,903,907 - 48,911,551 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0148,244,957 - 48,252,653 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl148,244,957 - 48,253,247 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1148,121,663 - 48,129,302 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0147,992,244 - 47,999,994 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0148,551,864 - 48,559,503 (-)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
DYNLT1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1148,058,804 - 48,066,389 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl148,058,804 - 48,066,609 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha148,903,907 - 48,911,551 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0148,244,957 - 48,252,653 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl148,244,957 - 48,253,247 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1148,121,663 - 48,129,302 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0147,992,244 - 47,999,994 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0148,551,864 - 48,559,503 (-)NCBIUU_Cfam_GSD_1.0
DYNLT1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh386158,636,474 - 158,644,743 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl6158,636,474 - 158,644,743 (-)EnsemblGRCh38hg38GRCh38
GRCh376159,057,506 - 159,065,775 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 366158,977,497 - 158,985,728 (-)NCBINCBI36Build 36hg18NCBI36
Build 346159,027,914 - 159,036,149NCBI
Celera6159,705,500 - 159,713,799 (-)NCBICelera
Cytogenetic Map6q25.3NCBI
HuRef6156,528,404 - 156,536,700 (-)NCBIHuRef
CHM1_16159,320,069 - 159,328,365 (-)NCBICHM1_1
T2T-CHM13v2.06159,881,698 - 159,889,969 (-)NCBIT2T-CHM13v2.0
Dynlt1b
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39176,697,511 - 6,703,695 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl176,697,511 - 6,703,695 (+)EnsemblGRCm39 Ensembl
GRCm38176,429,530 - 6,440,500 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl176,306,340 - 6,317,500 (-)EnsemblGRCm38mm10GRCm38
GRCm38.p6 Ensembl176,430,112 - 6,436,296 (+)EnsemblGRCm38mm10GRCm38
GRCm38.p6 Ensembl176,646,602 - 6,655,900 (-)EnsemblGRCm38mm10GRCm38
GRCm38.p6 Ensembl176,601,671 - 6,609,774 (+)EnsemblGRCm38mm10GRCm38
MGSCv37176,429,260 - 6,435,444 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36176,412,303 - 6,418,495 (-)NCBIMGSCv36mm8
Cytogenetic Map17A1NCBI
cM Map173.97NCBI
Dynlt1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8149,292,093 - 49,299,051 (-)NCBIGRCr8
mRatBN7.2146,887,017 - 46,893,956 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl146,887,017 - 46,893,881 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx147,435,976 - 47,442,799 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0153,423,238 - 53,430,061 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0147,511,411 - 47,518,234 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0147,206,892 - 47,213,785 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl147,206,895 - 47,213,749 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0148,510,103 - 48,516,996 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4141,097,174 - 41,103,997 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1141,100,118 - 41,106,942 (-)NCBI
Celera142,574,662 - 42,581,485 (-)NCBICelera
Cytogenetic Map1q11NCBI
Dynlt1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554393,833,525 - 3,842,393 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554393,833,525 - 3,842,393 (+)NCBIChiLan1.0ChiLan1.0
DYNLT1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v25178,744,093 - 178,752,350 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan16176,647,991 - 176,656,267 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v06156,530,068 - 156,538,346 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.16161,544,128 - 161,552,391 (-)NCBIpanpan1.1PanPan1.1panPan2
Dynlt1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404946143,077,230 - 143,083,807 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493648910,329,223 - 10,335,782 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493648910,329,223 - 10,335,758 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
DYNLT1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl18,556,059 - 8,563,676 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.118,556,083 - 8,562,865 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2110,385,073 - 10,391,588 (-)NCBISscrofa10.2Sscrofa10.2susScr3
DYNLT1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11386,210,462 - 86,218,002 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1386,210,465 - 86,217,956 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604058,592,316 - 58,599,872 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Dynlt1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624929968,823 - 976,414 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624929969,294 - 976,420 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in DYNLT1
84 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system reproductive system respiratory system adipose tissue
High
Medium 5 5 20 4 6 4 6 3 12 8 10 6
Low 2 2 2 3
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSCAFT00000001013   ⟹   ENSCAFP00000000928
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl148,058,804 - 48,066,609 (-)Ensembl
RefSeq Acc Id: ENSCAFT00845002265   ⟹   ENSCAFP00845001793
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl148,244,957 - 48,253,247 (-)Ensembl
RefSeq Acc Id: XM_003638782   ⟹   XP_003638830
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1148,058,804 - 48,066,389 (-)NCBI
Dog10K_Boxer_Tasha148,903,907 - 48,911,551 (-)NCBI
Sequence:
RefSeq Acc Id: XM_038465779   ⟹   XP_038321707
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.1148,121,663 - 48,129,302 (-)NCBI
RefSeq Acc Id: XM_038526448   ⟹   XP_038382376
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0148,551,864 - 48,559,503 (-)NCBI
RefSeq Acc Id: XM_038590745   ⟹   XP_038446673
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0147,992,244 - 47,993,729 (-)NCBI
RefSeq Acc Id: XM_038590746   ⟹   XP_038446674
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0147,992,244 - 47,999,994 (-)NCBI
RefSeq Acc Id: XM_038654535   ⟹   XP_038510463
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0148,244,957 - 48,246,386 (-)NCBI
RefSeq Acc Id: XM_038654536   ⟹   XP_038510464
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0148,244,957 - 48,252,653 (-)NCBI
Reference Protein Sequences
RefSeq Acc Id: XP_003638830   ⟸   XM_003638782
- Peptide Label: isoform X1
- UniProtKB: A0A8C0NCN5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSCAFP00000000928   ⟸   ENSCAFT00000001013
RefSeq Acc Id: XP_038321707   ⟸   XM_038465779
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038446674   ⟸   XM_038590746
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038446673   ⟸   XM_038590745
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038510464   ⟸   XM_038654536
- Peptide Label: isoform X1
- UniProtKB: A0A8C0NCN5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038510463   ⟸   XM_038654535
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038382376   ⟸   XM_038526448
- Peptide Label: isoform X1
- UniProtKB: A0A8C0NCN5 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSCAFP00845001793   ⟸   ENSCAFT00845002265


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000000657 Ensembl, UniProtKB/TrEMBL
  ENSCAFG00030015326 UniProtKB/TrEMBL
  ENSCAFG00040021879 UniProtKB/TrEMBL
  ENSCAFG00845001317 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000001013.5 UniProtKB/TrEMBL
  ENSCAFT00030028279.1 UniProtKB/TrEMBL
  ENSCAFT00040040626.1 UniProtKB/TrEMBL
  ENSCAFT00845002265.1 UniProtKB/TrEMBL
Gene3D-CATH 3.30.1140.40 UniProtKB/TrEMBL
InterPro Tctex-1-like UniProtKB/TrEMBL
  Tctex-1-like_sf UniProtKB/TrEMBL
KEGG Report cfa:100856149 UniProtKB/TrEMBL
NCBI Gene DYNLT1 ENTREZGENE
PANTHER DYNEIN LIGHT CHAIN TCTEX-TYPE 1 UniProtKB/TrEMBL
  PTHR21255 UniProtKB/TrEMBL
Pfam Tctex-1 UniProtKB/TrEMBL
UniProt A0A8C0NCN5 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C0TD90_CANLF UniProtKB/TrEMBL
  A0A8I3MK65_CANLF UniProtKB/TrEMBL
UniProt Secondary A0A8P0S6Y1 UniProtKB/TrEMBL
VGNC ID VGNC:54841 ENTREZGENE