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Gene: Masp2 (MBL associated serine protease 2) Rattus norvegicus

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Symbol:

Masp2

Name:

MBL associated serine protease 2

RGD ID:

620214

Description:

Enables serine-type endopeptidase activity. Predicted to be involved in complement activation, lectin pathway and zymogen activation. Predicted to act upstream of or within several processes, including activation of membrane attack complex; killing of cells of another organism; and opsonization. Predicted to be located in extracellular region. Predicted to be active in extracellular space and symbiont cell surface. Orthologous to human MASP2 (MBL associated serine protease 2); PARTICIPATES IN coagulation cascade pathway; complement system pathway; Staphylococcus aureus infection pathway; INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

mannan-binding lectin serine peptidase 2; mannan-binding lectin serine protease 2; mannose binding lectin-associated serine protease-2; mannose-binding protein-associated serine protease 2; MAp19; MASP-2; MBL-associated serine protease 2

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	5	164,319,017 - 164,332,686 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	5	164,308,991 - 164,332,705 (+)	Ensembl				GRCr8
mRatBN7.2	5	159,035,892 - 159,049,561 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	5	159,035,911 - 159,049,580 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	5	161,752,620 - 161,766,267 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	5	163,575,096 - 163,588,727 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	5	163,531,441 - 163,545,072 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	5	165,415,105 - 165,429,857 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	5	165,415,136 - 165,430,054 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	5	169,071,707 - 169,086,458 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	5	165,682,509 - 165,696,426 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	5	157,312,039 - 157,325,671 (+)	NCBI		Celera
RGSC_v3.1	5	165,692,831 - 165,706,614 (+)	NCBI
Cytogenetic Map	5	q36	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

erythema multiforme (ISO)

hypersensitivity reaction type III disease (ISO)

Inflammation (ISO)

MASP2 Deficiency (ISO)

Pneumococcal Pneumonia (ISO)

ulcerative colitis (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(+)-schisandrin B (EXP)

(1->4)-beta-D-glucan (ISO)

1,2,4-trichloro-5-(2,5-dichlorophenyl)benzene (ISO)

1,2-dichloroethane (ISO)

17beta-estradiol (ISO)

2,2',4,4',5,5'-hexachlorobiphenyl (ISO)

2,2',5,5'-tetrachlorobiphenyl (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2,4,4'-trichlorobiphenyl (ISO)

2,4-dibromophenyl 2,4,5-tribromophenyl ether (ISO)

2,4-dinitrotoluene (EXP)

3,4-methylenedioxymethamphetamine (ISO)

4,4'-sulfonyldiphenol (ISO)

5-methoxy-2-\{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl\}-1H-benzimidazole (EXP)

6-propyl-2-thiouracil (EXP)

acrylamide (EXP)

aflatoxin B1 (ISO)

amiodarone (EXP)

ammonium chloride (EXP)

aristolochic acid A (ISO)

benzbromarone (EXP)

benzo[a]pyrene (ISO)

benzo[e]pyrene (ISO)

bisphenol A (EXP,ISO)

cadmium atom (ISO)

cadmium dichloride (ISO)

cefaloridine (EXP)

CGP 52608 (ISO)

chlordecone (ISO)

clofibrate (EXP,ISO)

copper(II) sulfate (ISO)

crocidolite asbestos (ISO)

dibutyl phthalate (EXP)

dioxygen (EXP)

fipronil (EXP)

flutamide (EXP)

folic acid (ISO)

genistein (ISO)

gentamycin (EXP)

iron dichloride (ISO)

L-ethionine (EXP)

lead(0) (ISO)

methapyrilene (ISO)

N-Nitrosopyrrolidine (ISO)

nitrofen (EXP)

okadaic acid (ISO)

omeprazole (EXP)

PCB138 (ISO)

perfluorooctane-1-sulfonic acid (ISO)

pirinixic acid (EXP,ISO)

quercetin (EXP)

S-nitrosoglutathione (ISO)

sodium arsenite (ISO)

Soman (EXP)

tauroursodeoxycholic acid (EXP)

tetrachloroethene (ISO)

tetrachloromethane (EXP,ISO)

tetrodotoxin (ISO)

thioacetamide (EXP)

trichloroethene (EXP)

urethane (ISO)

valproic acid (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

cell surface pattern recognition receptor signaling pathway (ISO)

complement activation (IEA,NAS)

complement activation, classical pathway (IEA)

complement activation, lectin pathway (IBA,IEA,ISO,ISS)

immune system process (IEA)

innate immune response (IEA)

polyamine biosynthetic process (IEA)

polyamine metabolic process (IEA)

positive regulation of opsonization (ISO)

protein maturation (ISO)

proteolysis (IEA,ISO)

zymogen activation (ISO)

Cellular Component

extracellular region (IEA)

extracellular space (IBA)

Golgi apparatus (IEA,ISO)

serine-type endopeptidase complex (ISO)

symbiont cell surface (ISO,ISS)

Molecular Function

calcium ion binding (IEA)

calcium-dependent protein binding (IEA,ISO)

catalytic activity (IEA)

complement component C4b binding (IEA,ISO)

hydrolase activity (IEA)

identical protein binding (ISO)

metal ion binding (IEA)

peptidase activity (IDA,IEA,ISO)

protein binding (IPI,ISO)

serine-type endopeptidase activity (IBA,IDA,IEA,ISO)

serine-type peptidase activity (IEA)

transferase activity (IEA)

Molecular Pathway Annotations Click to see Annotation Detail View

coagulation cascade pathway (IEA)

complement system pathway (IEA)

Staphylococcus aureus infection pathway (IEA)

References

References - curated

#	Reference Title	Reference Citation
1.	Two mechanisms for mannose-binding protein modulation of the activity of its associated serine proteases.	Chen CB and Wallis R, J Biol Chem. 2004 Jun 18;279(25):26058-65. Epub 2004 Apr 1.
2.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3.	Rat ISS GO annotations from MGI mouse gene data--August 2006	MGD data from the GO Consortium
4.	Electronic Transfer of LocusLink and RefSeq Data	NCBI rat LocusLink and RefSeq merged data July 26, 2002
5.	OMIM Disease Annotation Pipeline	OMIM Disease Annotation Pipeline
6.	KEGG Annotation Import Pipeline	Pipeline to import KEGG annotations from KEGG into RGD
7.	GOA pipeline	RGD automated data pipeline
8.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
9.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
10.	The rat and mouse homologues of MASP-2 and MAp19, components of the lectin activation pathway of complement.	Stover CM, etal., J Immunol 1999 Dec 15;163(12):6848-59.
11.	Engineering novel complement activity into a pulmonary surfactant protein.	Venkatraman Girija U, etal., J Biol Chem. 2010 Apr 2;285(14):10546-52. doi: 10.1074/jbc.M109.097493. Epub 2010 Jan 29.
12.	Interaction of mannose-binding protein with associated serine proteases: effects of naturally occurring mutations.	Wallis R and Dodd RB, J Biol Chem 2000 Oct 6;275(40):30962-9.

Additional References at PubMed

PMID:9087411	PMID:10092804	PMID:10946292	PMID:12421953	PMID:12477932	PMID:12538697	PMID:12743029	PMID:15672593	PMID:16272342	PMID:16328467	PMID:17182967	PMID:17204478
PMID:17579066	PMID:19056867	PMID:22949645	PMID:23376485	PMID:23533145	PMID:28111019

Genomics

Comparative Map Data

Masp2
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	5	164,319,017 - 164,332,686 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	5	164,308,991 - 164,332,705 (+)	Ensembl				GRCr8
mRatBN7.2	5	159,035,892 - 159,049,561 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	5	159,035,911 - 159,049,580 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	5	161,752,620 - 161,766,267 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	5	163,575,096 - 163,588,727 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	5	163,531,441 - 163,545,072 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	5	165,415,105 - 165,429,857 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	5	165,415,136 - 165,430,054 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	5	169,071,707 - 169,086,458 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	5	165,682,509 - 165,696,426 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	5	157,312,039 - 157,325,671 (+)	NCBI		Celera
RGSC_v3.1	5	165,692,831 - 165,706,614 (+)	NCBI
Cytogenetic Map	5	q36	NCBI

MASP2
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	1	11,026,523 - 11,047,239 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	1	11,022,009 - 11,047,241 (-)	Ensembl			hg38	GRCh38
GRCh37	1	11,086,580 - 11,107,296 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	1	11,009,167 - 11,029,872 (-)	NCBI	Build 36	Build 36	hg18	NCBI36
Celera	1	10,198,893 - 10,219,593 (-)	NCBI		Celera
Cytogenetic Map	1	p36.22	NCBI
HuRef	1	10,238,261 - 10,258,777 (-)	NCBI		HuRef
CHM1_1	1	11,074,241 - 11,095,206 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	1	10,567,802 - 10,588,801 (-)	NCBI		T2T-CHM13v2.0

Masp2
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	4	148,679,079 - 148,699,939 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	4	148,687,011 - 148,699,956 (+)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	4	148,594,622 - 148,615,499 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	4	148,602,554 - 148,615,499 (+)	Ensembl			mm10	GRCm38
MGSCv37	4	147,976,653 - 147,989,591 (+)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	4	147,446,346 - 147,459,282 (+)	NCBI		MGSCv36	mm8
Celera	4	150,863,826 - 150,876,764 (+)	NCBI		Celera
Cytogenetic Map	4	E2	NCBI
cM Map	4	78.76	NCBI

Masp2
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955486	2,641,837 - 2,643,828 (+)	Ensembl
ChiLan1.0	NW_004955486	2,641,730 - 2,655,125 (+)	NCBI	ChiLan1.0	ChiLan1.0

MASP2
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	1	217,177,788 - 217,180,227 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	1	215,823,726 - 215,826,165 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	1	9,787,565 - 9,810,276 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	1	11,006,990 - 11,030,734 (-)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	1	11,009,760 - 11,030,734 (-)	Ensembl			panPan2	panpan1.1

MASP2
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	2	84,976,366 - 84,987,376 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	2	84,976,456 - 84,989,797 (+)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	2	81,505,721 - 81,517,987 (+)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	2	85,637,736 - 85,650,054 (+)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	2	85,637,807 - 85,651,149 (+)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	2	82,385,857 - 82,398,112 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	2	83,387,306 - 83,399,558 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	2	84,450,144 - 84,462,407 (+)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Masp2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405058	34,275,903 - 34,289,740 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936474	101,402 - 114,313 (-)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936474	100,584 - 113,781 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

MASP2
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	6	71,224,637 - 71,243,874 (-)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	6	71,224,637 - 71,243,041 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	6	65,144,361 - 65,150,710 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

MASP2
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	20	120,731,591 - 120,753,104 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
Vero_WHO_p1.0	NW_023666054	24,640,608 - 24,661,227 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Masp2
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla 1.0	NW_004624818	1,745,401 - 1,759,051 (+)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Masp2
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	1	12,160,089 - 12,173,027 (-)	NCBI		Rrattus_CSIRO_v1

Variants

Variants in Masp2
29 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	86
Count of miRNA genes:	76
Interacting mature miRNAs:	79
Transcripts:	ENSRNOT00000016317
Prediction methods:	Microtar, Miranda, Rnahybrid
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
10053720	Scort26	Serum corticosterone level QTL 26	2.06	0.0147	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	5	130249266	172190305	Rat
1354583	Despr3	Despair related QTL3	4.98	0.0002	locomotor behavior trait (VT:0001392)	amount of time spent in voluntary immobility (CMO:0001043)	5	132930505	172190305	Rat
61444	Strs2	Sensitivity to stroke QTL 2	4.7		cerebrum integrity trait (VT:0010549)	post-insult time to onset of cerebrovascular lesion (CMO:0002343)	5	141212838	172190305	Rat
1300119	Bp180	Blood pressure QTL 180	3.82		arterial blood pressure trait (VT:2000000)	blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)	5	149642129	171146538	Rat
1549904	Neuinf1	Neuroinflammation QTL 1	3	0	nervous system integrity trait (VT:0010566)	blood T lymphocyte count (CMO:0000110)	5	160111176	171146538	Rat
61452	Ciaa5	CIA Autoantibody QTL 5	3.5		blood autoantibody amount (VT:0003725)	calculated serum anti-rat type 2 collagen autoantibody titer (CMO:0001281)	5	99905133	172190305	Rat
8552908	Pigfal4	Plasma insulin-like growth factor 1 level QTL 4	6.6		blood insulin-like growth factor amount (VT:0010479)	plasma insulin-like growth factor 1 level (CMO:0001299)	5	133789363	172190305	Rat
1331803	Rf32	Renal function QTL 32	2.798		kidney blood vessel physiology trait (VT:0100012)	absolute change in renal vascular resistance (CMO:0001900)	5	134369199	172190305	Rat
61393	Bp7	Blood pressure QTL 7	4.5	0.0001	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	5	65089051	166764498	Rat
7794791	Mcs33	Mammary carcinoma susceptibility QTL 33	1.93		mammary gland integrity trait (VT:0010552)	mammary tumor incidence/prevalence measurement (CMO:0000946)	5	136631198	172190305	Rat
1354631	Swd2	Spike wave discharge measurement QTL 2	3.64	0.0002	brain electrophysiology trait (VT:0010557)	brain total spike-and-wave discharge duration (CMO:0001740)	5	156396728	172190305	Rat
1598861	Cm64	Cardiac mass QTL 64	2.9		heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	5	133081618	172190305	Rat
1578766	Tcas11	Tongue tumor susceptibility QTL 11	4.12		tongue integrity trait (VT:0010553)	number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)	5	51657967	166600247	Rat
631505	Bp103	Blood pressure QTL 103	3.2		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	5	138002522	170842766	Rat
1581505	Rf54	Renal function QTL 54			kidney physiology trait (VT:0002136)	kidney 20-HETE level (CMO:0001854)	5	133270647	172190305	Rat
1641920	Colcs1	Colorectal carcinoma susceptibility QTL 1	2.99	0.0055	intestine integrity trait (VT:0010554)	benign colorectal tumor surface area measurement (CMO:0001799)	5	160071170	172129029	Rat
2317753	Glom24	Glomerulus QTL 24	3.1		kidney glomerulus integrity trait (VT:0010546)	kidney sclerotic glomeruli count to total glomeruli count ratio (CMO:0001269)	5	141764300	172190305	Rat
1331721	Bp210	Blood pressure QTL 210	3.413		arterial blood pressure trait (VT:2000000)	blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)	5	148093485	172129029	Rat
8694169	Bw148	Body weight QTL 148	5	0.001	body mass (VT:0001259)	body weight gain (CMO:0000420)	5	133789363	172190305	Rat
1581510	Cm54	Cardiac mass QTL 54	3.4	0.05	heart left ventricle mass (VT:0007031)	heart left ventricle weight to body weight ratio (CMO:0000530)	5	125969677	172190305	Rat
1576312	Emca8	Estrogen-induced mammary cancer QTL 8	4.1		mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	5	55124766	172190305	Rat
631272	Lanf1	Left ventricular atrial natriuretic factor QTL 1	12		heart left ventricle natriuretic peptide A amount (VT:0010596)	heart left ventricle natriuretic peptide A level (CMO:0002165)	5	156396728	167181764	Rat
724525	Bp147	Blood pressure QTL 147	4.3	0.0001	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	5	131708216	172190305	Rat
2313096	Bmd78	Bone mineral density QTL 78	3.1	0.0001	tibia mineral mass (VT:1000283)	total volumetric bone mineral density (CMO:0001728)	5	149661912	166600247	Rat
1298090	Bp155	Blood pressure QTL 155	3.8		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	5	156289283	171137955	Rat
1598819	Bp292	Blood pressure QTL 292	4.3		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	5	133081618	172190305	Rat

Markers in Region

RH129791

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	5	159,037,096 - 159,037,746 (+)	MAPPER	mRatBN7.2
Rnor_6.0	5	165,416,346 - 165,416,995	NCBI	Rnor6.0
Rnor_5.0	5	169,072,947 - 169,073,596	UniSTS	Rnor5.0
RGSC_v3.4	5	165,683,694 - 165,684,343	UniSTS	RGSC3.4
Celera	5	157,313,224 - 157,313,873	UniSTS
RH 3.4 Map	5	1110.4	UniSTS
Cytogenetic Map	5	q36	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
16	12	43	140	91	90	59	91	59	6	324	167	10	119	74	89	31	17	17

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001429904	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_001429905	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_172043	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006239400	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006239401	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017593610	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063288351	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AJ277747	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AJ542538	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC128700	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473968	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CO557085	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000005	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	Y18285	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	Y18564	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	Y18565	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	Y18566	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	Y18567	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	Y18568	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	Y18569	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	Y18570	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	Y18571	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	Y18572	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	Y18573	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	Y19161	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	Y19162	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000016317 ⟹ ENSRNOP00000016317

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	5	159,035,911 - 159,049,580 (+)	Ensembl
Rnor_6.0 Ensembl	5	165,415,136 - 165,430,054 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000079407 ⟹ ENSRNOP00000072546

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	5	159,035,911 - 159,037,828 (+)	Ensembl
Rnor_6.0 Ensembl	5	165,415,278 - 165,417,077 (+)	Ensembl

RefSeq Acc Id:

NM_172043 ⟹ NP_742040

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	5	164,319,039 - 164,332,686 (+)	NCBI
mRatBN7.2	5	159,035,912 - 159,049,561 (+)	NCBI
Rnor_6.0	5	165,415,161 - 165,429,857 (+)	NCBI
Rnor_5.0	5	169,071,707 - 169,086,458 (+)	NCBI
RGSC_v3.4	5	165,682,509 - 165,696,426 (+)	RGD
Celera	5	157,312,039 - 157,325,671 (+)	RGD

Sequence:

show sequence

TGACAGGCGCTGGACCTGCAGAGCTGGGTGGCACACCATGAGGCTACTGATCGTCCTGGGTCTG
CTTTGGAGTTTGGTGGCCACACTTTTGGGCTCCAAGTGGCCTGAGCCTGTATTCGGGCGCCTGG
TGTCCCCTGGCTTCCCAGAGAAGTATGGCAACCATCAGGATCGATCCTGGACGCTGACTGCACC
CCCTGGCTTCCGCCTGCGCCTCTACTTCACCCACTTCAACCTGGAACTCTCTTACCGCTGCGAG
TATGACTTTGTCAAGTTGACCTCAGGGACCAAGGTGCTAGCCACGCTGTGTGGGCAGGAGAGTA
CAGATACTGAGCGGGCACCTGGCAATGACACCTTCTACTCACTGGGTCCCAGCCTAAAGGTCAC
CTTCCACTCCGACTACTCCAATGAGAAGCCATTCACAGGATTTGAGGCCTTCTATGCAGCGGAG
GATGTGGATGAATGCAGAACATCCCTGGGAGACTCAGTCCCTTGTGACCATTATTGCCACAACT
ACCTGGGCGGCTACTACTGCTCCTGCCGAGTGGGCTACATTCTGCACCAGAACAAGCATACCTG
CTCAGCCCTTTGTTCAGGCCAGGTGTTCACTGGGAGGTCTGGCTTTCTCAGTAGCCCTGAGTAC
CCACAGCCATACCCCAAACTCTCCAGCTGCGCCTACAACATCCGCCTGGAGGAAGGCTTCAGTA
TCACCCTGGACTTCGTGGAGTCCTTTGATGTGGAGATGCACCCTGAAGCCCAGTGCCCCTACGA
CTCCCTCAAGATTCAAACAGACAAGAGGGAATACGGCCCGTTTTGTGGGAAGACGCTGCCCCCC
AGGATTGAAACTGACAGCAACAAGGTGACCATTACCTTTACCACCGACGAGTCAGGGAACCACA
CAGGCTGGAAGATACACTACACAAGCACAGCACAGCCCTGCCCTGATCCAACGGCGCCACCTAA
TGGTCACATTTCACCTGTGCAAGCCACGTATGTCCTGAAGGACAGCTTTTCTGTCTTCTGCAAG
ACTGGCTTCGAGCTTCTGCAAGGTTCTGTCCCCCTGAAGTCATTCACTGCTGTCTGTCAGAAAG
ATGGATCTTGGGACCGGCCGATACCAGAGTGCAGCATTATTGACTGTGGCCCTCCCGATGACCT
ACCCAATGGCCACGTGGACTATATCACAGGCCCTGAAGTGACCACCTACAAAGCTGTGATTCAG
TACAGCTGTGAAGAGACTTTCTACACAATGAGCAGCAATGGTAAATATGTGTGTGAGGCTGATG
GATTCTGGACGAGCTCCAAAGGAGAAAAATCCCTCCCGGTTTGCAAGCCTGTCTGTGGACTGTC
CACACACACTTCAGGAGGCCGTATAATTGGAGGACAGCCTGCAAAGCCTGGTGACTTTCCTTGG
CAAGTCTTGTTACTGGGTGAAACTACAGCAGCAGGTGCTCTTATACATGACGACTGGGTCCTAA
CAGCGGCTCATGCTGTATATGGGAAAACAGAGGCGATGTCCTCCCTGGACATCCGCATGGGCAT
CCTCAAAAGGCTCTCCCCTCATTACACTCAAGCCTGGCCAGAGGCTGTCTTTATCCATGAAGGC
TACACTCACGGAGCTGGTTTTGACAATGATATAGCACTGATTAAACTCAAGAACAAAGTCACAA
TCAACAGAAACATCATGCCGATTTGTCTACCAAGAAAAGAAGCTGCATCCTTAATGAAAACAGA
CTTCGTTGGAACTGTGGCTGGCTGGGGGTTAACCCAGAAGGGGTTTCTTGCTAGAAACCTAATG
TTTGTGGACATACCAATTGTTGACCACCAAAAATGTGCTACTGCGTATACAAAGCAGCCCTACC
CAGGAGCAAAAGTGACTGTTAACATGCTCTGTGCTGGCCTAGACGCCGGTGGCAAGGACAGCTG
CAGAGGTGACAGCGGAGGGGCATTAGTGTTTCTAGACAATGAAACACAGAGATGGTTTGTGGGA
GGAATAGTTTCCTGGGGTTCTATTAACTGTGGGGGGTCAGAACAGTATGGGGTCTACACGAAAG
TCACGAACTATATTCCCTGGATTGAGAACATAATAAATAATTTCTAA

hide sequence

RefSeq Acc Id:

XM_006239400 ⟹ XP_006239462

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	5	164,319,017 - 164,324,923 (+)	NCBI
mRatBN7.2	5	159,035,892 - 159,040,860 (+)	NCBI
Rnor_6.0	5	165,415,105 - 165,420,399 (+)	NCBI
Rnor_5.0	5	169,071,707 - 169,086,458 (+)	NCBI

Sequence:

show sequence

GGAGGCTGGGGGTGGGGCTGGGGGTGGGGCCTGGTGCTGGACAAACAGGTCAAAGGTGACAGGC
GCTGGACCTGCAGAGCTGGGTGGCACACCATGAGGCTACTGATCGTCCTGGGTCTGCTTTGGAG
TTTGGTGGCCACACTTTTGGGCTCCAAGTGGCCTGAGCCTGTATTCGGGCGCCTGGTGTCCCCT
GGCTTCCCAGAGAAGTATGGCAACCATCAGGATCGATCCTGGACGCTGACTGCACCCCCTGGCT
TCCGCCTGCGCCTCTACTTCACCCACTTCAACCTGGAACTCTCTTACCGCTGCGAGTATGACTT
TGTCAAGTTGACCTCAGGGACCAAGGTGCTAGCCACGCTGTGTGGGCAGGAGAGTACAGATACT
GAGCGGGCACCTGGCAATGACACCTTCTACTCACTGGGTCCCAGCCTAAAGGTCACCTTCCACT
CCGACTACTCCAATGAGAAGCCATTCACAGGATTTGAGGCCTTCTATGCAGCGGAGGATGTGGA
TGAATGCAGAACATCCCTGGGAGACTCAGTCCCTTGTGACCATTATTGCCACAACTACCTGGGC
GGCTACTACTGCTCCTGCCGAGTGGGCTACATTCTGCACCAGAACAAGCATACCTGCTCAGCCC
TTTGTTCAGGCCAGGTGTTCACTGGGAGGTCTGGCTTTCTCAGTAGCCCTGAGTACCCACAGCC
ATACCCCAAACTCTCCAGCTGCGCCTACAACATCCGCCTGGAGGAAGGCTTCAGTATCACCCTG
GACTTCGTGGAGTCCTTTGATGTGGAGATGCACCCTGAAGCCCAGTGCCCCTACGACTCCCTCA
AGATTCAAACAGACAAGAGGGAATACGGCCCGTTTTGTGGGAAGACGCTGCCCCCCAGGATTGA
AACTGACAGCAACAAGGTGACCATTACCTTTACCACCGACGAGTCAGGGAACCACACAGGCTGG
AAGATACACTACACAAGCACAGATTAAGAAGAAAATTGTCAAAAATACTAAGTGCGGAGGACAG
GGTCCGAACAGCATCTGCTCTCAGTCCAGAGGGGAAATGAAGTCGCTGTGGCACGGCCTTTGAG
TCAAGCATGTAGTAGAGTAAAATGGGGGTGGGAGCTCAGAGTGGGACATCAACATTGTTACTCA
TCTGTCTTGCTCTTTTCCTAGAAGTGACACTCTTGGCTTCAAACCACATGTATAATCTTCCTGG
CATAGACATTCCATCATTCTGGGATATCTGATTTTTTGGGGGGGAGGAGGTGGGAGGACACAAA
GCAGTGGTGTCTCAGGACAGGGTTTCTCTGCATAATAGCACTGGCTGTCCTTGAACTCACTTTG
TAGGCCATGCTTGTCCCAAACTCACAGAATTTACCGGCTTTTGGGCTGGAGAGATGGCTCAGCG
GTTAAGAGCACTGACTGCTCTTCCAGAGGTCCTGAG

hide sequence

RefSeq Acc Id:

XM_006239401 ⟹ XP_006239463

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	5	164,319,017 - 164,320,956 (+)	NCBI
mRatBN7.2	5	159,035,892 - 159,037,829 (+)	NCBI
Rnor_6.0	5	165,415,106 - 165,417,078 (+)	NCBI
Rnor_5.0	5	169,071,707 - 169,086,458 (+)	NCBI

Sequence:

show sequence

GAGGCTGGGGGTGGGGCTGGGGGTGGGGCCTGGTGCTGGACAAACAGGTCAAAGGTGACAGGCG
CTGGACCTGCAGAGCTGGGTGGCACACCATGAGGCTACTGATCGTCCTGGGTCTGCTTTGGAGT
TTGGTGGCCACACTTTTGGGCTCCAAGTGGCCTGAGCCTGTATTCGGGCGCCTGGTGTCCCCTG
GCTTCCCAGAGAAGTATGGCAACCATCAGGATCGATCCTGGACGCTGACTGCACCCCCTGGCTT
CCGCCTGCGCCTCTACTTCACCCACTTCAACCTGGAACTCTCTTACCGCTGCGAGTATGACTTT
GTCAAGTTGACCTCAGGGACCAAGGTGCTAGCCACGCTGTGTGGGCAGGAGAGTACAGATACTG
AGCGGGCACCTGGCAATGACACCTTCTACTCACTGGGTCCCAGCCTAAAGGTCACCTTCCACTC
CGACTACTCCAATGAGAAGCCATTCACAGGATTTGAGGCCTTCTATGCAGCGGAGGATGTGGAT
GAATGCAGAACATCCCTGGGAGACTCAGTCCCTTGTGACCATTATTGCCACAACTACCTGGGCG
GCTACTACTGCTCCTGCCGAGTGGGCTACATTCTGCACCAGAACAAGCATACCTGCTCAGAGCA
GAGCCTCTAACCTCCCTCGCTCCAGCCTGCCCACCCCAGTGAGTCAGACACCAGTCAATACATG
CCCACACGACTCAGCTCTGTCAGGCTGGAGTGGCTGCCAGCACCCATTCACCTTTCCCAGACAA
TAAACCTGCCTCCACTTCCA

hide sequence

RefSeq Acc Id:

XM_063288351 ⟹ XP_063144421

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	5	164,319,017 - 164,331,592 (+)	NCBI

Protein Sequences


Protein RefSeqs	NP_001416833	(Get FASTA)	NCBI Sequence Viewer
	NP_001416834	(Get FASTA)	NCBI Sequence Viewer
	NP_742040	(Get FASTA)	NCBI Sequence Viewer
	XP_006239462	(Get FASTA)	NCBI Sequence Viewer
	XP_006239463	(Get FASTA)	NCBI Sequence Viewer
	XP_063144421	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAI28701	(Get FASTA)	NCBI Sequence Viewer
	CAB50738	(Get FASTA)	NCBI Sequence Viewer
	CAB65248	(Get FASTA)	NCBI Sequence Viewer
	CAB65249	(Get FASTA)	NCBI Sequence Viewer
	CAB65382	(Get FASTA)	NCBI Sequence Viewer
	CAB65383	(Get FASTA)	NCBI Sequence Viewer
	CAB65384	(Get FASTA)	NCBI Sequence Viewer
	CAB65385	(Get FASTA)	NCBI Sequence Viewer
	CAB65386	(Get FASTA)	NCBI Sequence Viewer
	CAB65387	(Get FASTA)	NCBI Sequence Viewer
	CAB65388	(Get FASTA)	NCBI Sequence Viewer
	CAB65389	(Get FASTA)	NCBI Sequence Viewer
	CAB65390	(Get FASTA)	NCBI Sequence Viewer
	CAB70973	(Get FASTA)	NCBI Sequence Viewer
	CAB90832	(Get FASTA)	NCBI Sequence Viewer
	CAD66058	(Get FASTA)	NCBI Sequence Viewer
	EDL81126	(Get FASTA)	NCBI Sequence Viewer
	EDL81127	(Get FASTA)	NCBI Sequence Viewer
	EDL81128	(Get FASTA)	NCBI Sequence Viewer
	EDL81129	(Get FASTA)	NCBI Sequence Viewer
	EDL81130	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000016317
GenBank Protein	Q9JJS8	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:	NP_742040 ⟸ NM_172043
- Peptide Label:	precursor
- UniProtKB:	Q9WUZ0 (UniProtKB/Swiss-Prot), Q9QXD4 (UniProtKB/Swiss-Prot), Q9QX91 (UniProtKB/Swiss-Prot), Q9QX90 (UniProtKB/Swiss-Prot), Q9QX89 (UniProtKB/Swiss-Prot), Q9QX88 (UniProtKB/Swiss-Prot), Q9QX87 (UniProtKB/Swiss-Prot), Q9QX86 (UniProtKB/Swiss-Prot), Q9QX85 (UniProtKB/Swiss-Prot), Q9QX84 (UniProtKB/Swiss-Prot), Q9QX83 (UniProtKB/Swiss-Prot), Q9JJP3 (UniProtKB/Swiss-Prot), Q9JJS8 (UniProtKB/Swiss-Prot), A2VCV7 (UniProtKB/TrEMBL), F7FHD3 (UniProtKB/TrEMBL)
- Sequence:	show sequence MRLLIVLGLLWSLVATLLGSKWPEPVFGRLVSPGFPEKYGNHQDRSWTLTAPPGFRLRLYFTHF NLELSYRCEYDFVKLTSGTKVLATLCGQESTDTERAPGNDTFYSLGPSLKVTFHSDYSNEKPFT GFEAFYAAEDVDECRTSLGDSVPCDHYCHNYLGGYYCSCRVGYILHQNKHTCSALCSGQVFTGR SGFLSSPEYPQPYPKLSSCAYNIRLEEGFSITLDFVESFDVEMHPEAQCPYDSLKIQTDKREYG PFCGKTLPPRIETDSNKVTITFTTDESGNHTGWKIHYTSTAQPCPDPTAPPNGHISPVQATYVL KDSFSVFCKTGFELLQGSVPLKSFTAVCQKDGSWDRPIPECSIIDCGPPDDLPNGHVDYITGPE VTTYKAVIQYSCEETFYTMSSNGKYVCEADGFWTSSKGEKSLPVCKPVCGLSTHTSGGRIIGGQ PAKPGDFPWQVLLLGETTAAGALIHDDWVLTAAHAVYGKTEAMSSLDIRMGILKRLSPHYTQAW PEAVFIHEGYTHGAGFDNDIALIKLKNKVTINRNIMPICLPRKEAASLMKTDFVGTVAGWGLTQ KGFLARNLMFVDIPIVDHQKCATAYTKQPYPGAKVTVNMLCAGLDAGGKDSCRGDSGGALVFLD NETQRWFVGGIVSWGSINCGGSEQYGVYTKVTNYIPWIENIINNF hide sequence

RefSeq Acc Id:

XP_006239462 ⟸ XM_006239400

- Peptide Label:

isoform X2

- Sequence:

show sequence

MRLLIVLGLLWSLVATLLGSKWPEPVFGRLVSPGFPEKYGNHQDRSWTLTAPPGFRLRLYFTHF
NLELSYRCEYDFVKLTSGTKVLATLCGQESTDTERAPGNDTFYSLGPSLKVTFHSDYSNEKPFT
GFEAFYAAEDVDECRTSLGDSVPCDHYCHNYLGGYYCSCRVGYILHQNKHTCSALCSGQVFTGR
SGFLSSPEYPQPYPKLSSCAYNIRLEEGFSITLDFVESFDVEMHPEAQCPYDSLKIQTDKREYG
PFCGKTLPPRIETDSNKVTITFTTDESGNHTGWKIHYTSTD

hide sequence

RefSeq Acc Id:	XP_006239463 ⟸ XM_006239401
- Peptide Label:	isoform X3
- Sequence:	show sequence MRLLIVLGLLWSLVATLLGSKWPEPVFGRLVSPGFPEKYGNHQDRSWTLTAPPGFRLRLYFTHF NLELSYRCEYDFVKLTSGTKVLATLCGQESTDTERAPGNDTFYSLGPSLKVTFHSDYSNEKPFT GFEAFYAAEDVDECRTSLGDSVPCDHYCHNYLGGYYCSCRVGYILHQNKHTCSEQSL hide sequence

Ensembl Acc Id:

ENSRNOP00000072546 ⟸ ENSRNOT00000079407

Ensembl Acc Id:

ENSRNOP00000016317 ⟸ ENSRNOT00000016317

RefSeq Acc Id:	XP_063144421 ⟸ XM_063288351
- Peptide Label:	isoform X1

Protein Domains

CUB EGF-like Peptidase S1 Sushi

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q9JJS8-F1-model_v2	AlphaFold	Q9JJS8	1-685	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13694265

Promoter ID:

EPDNEW_R4789

Type:

initiation region

Name:

Masp2_1

Description:

mannan-binding lectin serine peptidase 2

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	5	165,415,180 - 165,415,240	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:620214	AgrOrtholog
BioCyc Gene	G2FUF-39159	BioCyc
Ensembl Genes	ENSRNOG00000011258	Ensembl, ENTREZGENE
Ensembl Transcript	ENSRNOT00000016317	ENTREZGENE
Gene3D-CATH	2.40.10.10	UniProtKB/Swiss-Prot
	2.60.120.290	UniProtKB/Swiss-Prot
	Complement Module, domain 1	UniProtKB/Swiss-Prot
	Laminin	UniProtKB/Swiss-Prot
IMAGE_CLONE	IMAGE:7324989	IMAGE-MGC_LOAD
InterPro	CUB_dom	UniProtKB/Swiss-Prot
	EGF-like_Ca-bd_dom	UniProtKB/Swiss-Prot
	EGF-like_dom	UniProtKB/Swiss-Prot
	EGF_Ca-bd_CS	UniProtKB/Swiss-Prot
	NOTCH1_EGF-like	UniProtKB/Swiss-Prot
	Pept_S1A_C1r/C1S/mannan-bd	UniProtKB/Swiss-Prot
	Peptidase_S1_PA	UniProtKB/Swiss-Prot
	Peptidase_S1_PA_chymotrypsin	UniProtKB/Swiss-Prot
	Peptidase_S1A	UniProtKB/Swiss-Prot
	Sperma_CUB_dom_sf	UniProtKB/Swiss-Prot
	Sushi/SCR/CCP_sf	UniProtKB/Swiss-Prot
	Sushi_SCR_CCP_dom	UniProtKB/Swiss-Prot
	Trypsin_dom	UniProtKB/Swiss-Prot
	TRYPSIN_SER	UniProtKB/Swiss-Prot
KEGG Report	rno:64459	UniProtKB/Swiss-Prot
MGC_CLONE	MGC:156488	IMAGE-MGC_LOAD
NCBI Gene	64459	ENTREZGENE
PANTHER	COMPLEMENT COMPONENT 1, S SUBCOMPONENT-RELATED	UniProtKB/Swiss-Prot
	PTHR24255:SF10	UniProtKB/Swiss-Prot
Pfam	CUB	UniProtKB/Swiss-Prot
	EGF_CA	UniProtKB/Swiss-Prot
	Sushi	UniProtKB/Swiss-Prot
	Trypsin	UniProtKB/Swiss-Prot
PhenoGen	Masp2	PhenoGen
PIRSF	C1r_C1s_MASP	UniProtKB/Swiss-Prot
PRINTS	CHYMOTRYPSIN	UniProtKB/Swiss-Prot
PROSITE	ASX_HYDROXYL	UniProtKB/Swiss-Prot
	CUB	UniProtKB/Swiss-Prot
	EGF_2	UniProtKB/Swiss-Prot
	EGF_CA	UniProtKB/Swiss-Prot
	SUSHI	UniProtKB/Swiss-Prot
	TRYPSIN_DOM	UniProtKB/Swiss-Prot
	TRYPSIN_SER	UniProtKB/Swiss-Prot
RatGTEx	ENSRNOG00000011258	RatGTEx
SMART	CCP	UniProtKB/Swiss-Prot
	CUB	UniProtKB/Swiss-Prot
	EGF	UniProtKB/Swiss-Prot
	EGF_CA	UniProtKB/Swiss-Prot
	Tryp_SPc	UniProtKB/Swiss-Prot
Superfamily-SCOP	EGF/Laminin	UniProtKB/Swiss-Prot
	SSF49854	UniProtKB/Swiss-Prot
	SSF50494	UniProtKB/Swiss-Prot
	SSF57535	UniProtKB/Swiss-Prot
UniProt	A0A0G2K392	ENTREZGENE, UniProtKB/TrEMBL
	A0ABK0M2R6_RAT	UniProtKB/TrEMBL
	A2VCV7	ENTREZGENE, UniProtKB/TrEMBL
	A6IU76	ENTREZGENE, UniProtKB/TrEMBL
	A6IU77_RAT	UniProtKB/TrEMBL
	A6IU78_RAT	UniProtKB/TrEMBL
	A6IU79_RAT	UniProtKB/TrEMBL
	F7FHD3	ENTREZGENE, UniProtKB/TrEMBL
	MASP2_RAT	UniProtKB/Swiss-Prot
	Q9JJP3	ENTREZGENE
	Q9JJS8	ENTREZGENE
	Q9QX83	ENTREZGENE
	Q9QX84	ENTREZGENE
	Q9QX85	ENTREZGENE
	Q9QX86	ENTREZGENE
	Q9QX87	ENTREZGENE
	Q9QX88	ENTREZGENE
	Q9QX89	ENTREZGENE
	Q9QX90	ENTREZGENE
	Q9QX91	ENTREZGENE
	Q9QXD4	ENTREZGENE
	Q9WUZ0	ENTREZGENE
UniProt Secondary	Q9JJP3	UniProtKB/Swiss-Prot
	Q9QX83	UniProtKB/Swiss-Prot
	Q9QX84	UniProtKB/Swiss-Prot
	Q9QX85	UniProtKB/Swiss-Prot
	Q9QX86	UniProtKB/Swiss-Prot
	Q9QX87	UniProtKB/Swiss-Prot
	Q9QX88	UniProtKB/Swiss-Prot
	Q9QX89	UniProtKB/Swiss-Prot
	Q9QX90	UniProtKB/Swiss-Prot
	Q9QX91	UniProtKB/Swiss-Prot
	Q9QXD4	UniProtKB/Swiss-Prot
	Q9WUZ0	UniProtKB/Swiss-Prot

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2021-02-18	Masp2	MBL associated serine protease 2	Masp2	mannan-binding lectin serine peptidase 2	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2006-03-30	Masp2	mannan-binding lectin serine peptidase 2		mannan-binding lectin serine protease 2	Name updated	1299863	APPROVED
2004-09-10	Masp2	mannan-binding lectin serine protease 2		MASP-2 protein	Name updated	1299863	APPROVED
2002-08-07	Masp2	MASP-2 protein			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - OMIM

Imported Annotations - KEGG (archival)

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Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - OMIM

Imported Annotations - KEGG (archival)