Fgf4 (fibroblast growth factor 4) - Rat Genome Database

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Gene: Fgf4 (fibroblast growth factor 4) Rattus norvegicus
Analyze
Symbol: Fgf4
Name: fibroblast growth factor 4
RGD ID: 620127
Description: Predicted to enable fibroblast growth factor receptor binding activity and growth factor activity. Predicted to be involved in several processes, including chondroblast differentiation; positive regulation of ERK1 and ERK2 cascade; and regulation of endothelial cell chemotaxis to fibroblast growth factor. Predicted to act upstream of or within several processes, including cellular response to leukemia inhibitory factor; positive regulation of macromolecule metabolic process; and skeletal system morphogenesis. Predicted to be active in cytoplasm and extracellular space. Orthologous to human FGF4 (fibroblast growth factor 4); PARTICIPATES IN fibroblast growth factor signaling pathway; melanoma pathway; mitogen activated protein kinase signaling pathway; INTERACTS WITH ammonium chloride; bisphenol A; copper atom.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: Fgf7a; fibroblast growth factor 7a; heparin-binding growth factor 1; Hst; Hst1
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81209,453,229 - 209,457,085 (+)NCBIGRCr8
mRatBN7.21200,023,937 - 200,027,793 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1200,024,056 - 200,025,466 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1208,405,105 - 208,408,963 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01215,491,358 - 215,495,214 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01208,165,562 - 208,169,418 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01218,024,537 - 218,029,539 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1218,025,810 - 218,027,220 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01224,895,162 - 224,896,687 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41205,292,272 - 205,293,705 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11205,445,724 - 205,447,158 (+)NCBI
Celera1197,582,129 - 197,583,539 (+)NCBICelera
Cytogenetic Map1q42NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Fgf4RatAicardi-Goutieres Syndrome 3  ISOFGF4 (Homo sapiens)8554872ClinVar Annotator: match by term: Aicardi-Goutieres syndrome 3ClinVarPMID:28492532
Fgf4Ratimmunodeficiency 90  ISOFGF4 (Homo sapiens)8554872ClinVar Annotator: match by term: Infections more ...ClinVarPMID:28492532
Fgf4Ratintellectual disability  ISOFGF4 (Homo sapiens)8554872ClinVar Annotator: match by term: Intellectual disabilityClinVar 
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Fgf4RatBreast Neoplasms  ISOFGF4 (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:21936542
Fgf4Rathepatocellular carcinoma  ISOFGF4 (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:25822088
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Fgf4RatPilonidal Sinus  ISOFGF4 (Canis lupus familiaris)9068941Dermoid sinusOMIAPMID:10713979 more ...

1 to 20 of 62 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Fgf4Rat17beta-estradiol increases expressionISOFGF4 (Homo sapiens)6480464Estradiol results in increased expression of FGF4 mRNACTDPMID:21098263
Fgf4Rat3-isobutyl-1-methyl-7H-xanthine multiple interactionsISOFGF4 (Homo sapiens)6480464[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in increased expression of FGF4 mRNACTDPMID:28628672
Fgf4Rat4,4'-sulfonyldiphenol increases expressionISOFgf4 (Mus musculus)6480464bisphenol S results in increased expression of FGF4 mRNACTDPMID:30951980
Fgf4Rat4,4'-sulfonyldiphenol decreases methylationISOFGF4 (Homo sapiens)6480464bisphenol S results in decreased methylation of FGF4 geneCTDPMID:31601247
Fgf4Rat5-aza-2'-deoxycytidine increases expressionISOFgf4 (Mus musculus)6480464Decitabine results in increased expression of FGF4 mRNACTDPMID:27915011
Fgf4Rat5-fluorouracil affects expressionISOFgf4 (Mus musculus)6480464Fluorouracil affects the expression of FGF4 proteinCTDPMID:21296659
Fgf4Ratacetic acid increases expressionISOFgf4 (Mus musculus)6480464Acetic Acid results in increased expression of FGF4 proteinCTDPMID:21296659
Fgf4Ratall-trans-retinoic acid multiple interactionsISOFgf4 (Mus musculus)6480464NR6A1 protein affects the reaction [Tretinoin results in decreased expression of FGF4 mRNA]CTDPMID:16166633
Fgf4Ratall-trans-retinoic acid affects expressionISOFGF4 (Homo sapiens)6480464Tretinoin affects the expression of FGF4 mRNACTDPMID:31600526
Fgf4Ratammonium chloride affects expressionEXP 6480464Ammonium Chloride affects the expression of FGF4 mRNACTDPMID:16483693
Fgf4Ratamphotericin B increases expressionISOFGF4 (Homo sapiens)6480464Amphotericin B analog results in increased expression of FGF4 mRNACTDPMID:28534445
Fgf4Ratarsenite(3-) decreases methylationISOFGF4 (Homo sapiens)6480464arsenite results in decreased methylation of FGF4 promoterCTDPMID:23974009
Fgf4Ratbelinostat increases expressionISOFGF4 (Homo sapiens)6480464belinostat results in increased expression of FGF4 mRNACTDPMID:26272509
Fgf4Ratbelinostat multiple interactionsISOFGF4 (Homo sapiens)6480464[NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of FGF4 mRNACTDPMID:27188386
Fgf4Ratbenzo[a]pyrene increases methylationISOFGF4 (Homo sapiens)6480464Benzo(a)pyrene results in increased methylation of FGF4 exonCTDPMID:27901495
Fgf4Ratbenzo[a]pyrene affects methylationISOFGF4 (Homo sapiens)6480464Benzo(a)pyrene affects the methylation of FGF4 promoterCTDPMID:27901495
Fgf4Ratbis(2-ethylhexyl) phthalate decreases expressionISOFGF4 (Homo sapiens)6480464Diethylhexyl Phthalate results in decreased expression of FGF4 mRNACTDPMID:31163220
Fgf4Ratbisphenol A decreases expressionISOFgf4 (Mus musculus)6480464bisphenol A results in decreased expression of FGF4 mRNACTDPMID:25270620
Fgf4Ratbisphenol A decreases expressionEXP 6480464bisphenol A results in decreased expression of FGF4 mRNACTDPMID:25181051
Fgf4Ratbisphenol F multiple interactionsISOFGF4 (Homo sapiens)6480464[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in increased expression of FGF4 mRNACTDPMID:28628672

1 to 20 of 62 rows

Biological Process
1 to 20 of 56 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Fgf4Ratapoptotic process acts_upstream_ofISOFgf4 (Mus musculus)1624291MGI:99604 PMID:16245339RGDPMID:16245339
Fgf4Ratapoptotic process acts_upstream_ofIEAUniProtKB:P11403 and ensembl:ENSMUSP000000567521600115GO_REF:0000107EnsemblGO_REF:0000107
Fgf4Ratapoptotic process involved in morphogenesis acts_upstream_of_or_withinISOFgf4 (Mus musculus)1624291MGI:96970 PMID:15649466RGDPMID:15649466
Fgf4Ratapoptotic process involved in morphogenesis acts_upstream_of_or_withinIEAUniProtKB:P11403 and ensembl:ENSMUSP000000567521600115GO_REF:0000107EnsemblGO_REF:0000107
Fgf4Ratcartilage condensation acts_upstream_of_or_withinIEAUniProtKB:P11403 and ensembl:ENSMUSP000000567521600115GO_REF:0000107EnsemblGO_REF:0000107
Fgf4Ratcartilage condensation acts_upstream_of_or_withinISOFgf4 (Mus musculus)1624291MGI:98726 PMID:8565825RGDPMID:8565825
Fgf4Ratcell population proliferation acts_upstream_ofISOFgf4 (Mus musculus)1624291MGI:99604 PMID:16245339RGDPMID:16245339
Fgf4Ratcell population proliferation acts_upstream_ofIEAUniProtKB:P11403 and ensembl:ENSMUSP000000567521600115GO_REF:0000107EnsemblGO_REF:0000107
Fgf4Ratcellular response to leukemia inhibitory factor acts_upstream_of_or_withinISOFgf4 (Mus musculus)1624291 PMID:20439489RGDPMID:20439489
Fgf4Ratcellular response to leukemia inhibitory factor acts_upstream_of_or_withinIEAUniProtKB:P11403 and ensembl:ENSMUSP000000567521600115GO_REF:0000107EnsemblGO_REF:0000107
Fgf4Ratchondroblast differentiation involved_inISOFGF4 (Homo sapiens)1624291 PMID:17167778RGDPMID:17167778
Fgf4Ratchondroblast differentiation involved_inIEAUniProtKB:P08620 and ensembl:ENSP000001687121600115GO_REF:0000107EnsemblGO_REF:0000107
Fgf4Ratcranial suture morphogenesis acts_upstream_of_or_withinIEAUniProtKB:P11403 and ensembl:ENSMUSP000000567521600115GO_REF:0000107EnsemblGO_REF:0000107
Fgf4Ratcranial suture morphogenesis acts_upstream_of_or_withinISOFgf4 (Mus musculus)1624291 PMID:9477322RGDPMID:9477322
Fgf4Ratembryonic hindlimb morphogenesis acts_upstream_of_or_withinISOFgf4 (Mus musculus)1624291MGI:99604 PMID:16245339RGDPMID:16245339
Fgf4Ratembryonic hindlimb morphogenesis acts_upstream_of_or_withinIEAUniProtKB:P11403 and ensembl:ENSMUSP000000567521600115GO_REF:0000107EnsemblGO_REF:0000107
Fgf4Ratembryonic limb morphogenesis acts_upstream_of_or_withinISOFgf4 (Mus musculus)1624291MGI:99604 PMID:15328019RGDPMID:15328019
Fgf4Ratembryonic limb morphogenesis acts_upstream_of_or_withinIEAUniProtKB:P11403 and ensembl:ENSMUSP000000567521600115GO_REF:0000107EnsemblGO_REF:0000107
Fgf4Ratepithelial cell apoptotic process acts_upstream_of_or_withinISOFgf4 (Mus musculus)1624291MGI:96970 PMID:15649466RGDPMID:15649466
Fgf4Ratepithelial cell apoptotic process acts_upstream_of_or_withinIEAUniProtKB:P11403 and ensembl:ENSMUSP000000567521600115GO_REF:0000107EnsemblGO_REF:0000107
1 to 20 of 56 rows

Cellular Component

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Fgf4Ratcytoplasm is_active_inIBAMGI:109178 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Fgf4Ratextracellular space is_active_inIBAMGI:1099809 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033

Molecular Function

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Fgf4Ratfibroblast growth factor receptor binding enablesIBAFB:FBgn0014135 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Fgf4Ratgrowth factor activity enablesIEAInterPro:IPR0022091600115GO_REF:0000002InterProGO_REF:0000002
Fgf4Ratgrowth factor activity enablesIBAMGI:95516 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Fgf4Ratprotein binding enablesISOFgf4 (Mus musculus)1624291PR:P21803 PMID:8393815RGDPMID:8393815

Imported Annotations - KEGG (archival)

Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Fgf4Ratmelanoma pathway  IEA 6907045 KEGGrno:05218
Fgf4Ratmitogen activated protein kinase signaling pathway   IEA 6907045 KEGGrno:04010

Imported Annotations - PID (archival)

Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Fgf4Ratfibroblast growth factor signaling pathway  ISOFGF4 (Homo sapiens)6484113 PIDPID:200220

#
Reference Title
Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Synergistic effect of fibroblast growth factor-4 in ectopic bone formation induced by bone morphogenetic protein-2. Kubota K, etal., Bone 2002 Oct;31(4):465-71.
3. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
4. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
5. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
6. PID Annotation Import Pipeline Pipeline to import Pathway Interaction Database annotations from NCI into RGD
7. GOA pipeline RGD automated data pipeline
8. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
PMID:8565825   PMID:8663044   PMID:8898217   PMID:9244299   PMID:9477322   PMID:11023873   PMID:12502739   PMID:15328019   PMID:15328412   PMID:15649466   PMID:16245339   PMID:16756958  
PMID:17167778   PMID:17951031   PMID:19289495   PMID:20439489   PMID:32788570  



Fgf4
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81209,453,229 - 209,457,085 (+)NCBIGRCr8
mRatBN7.21200,023,937 - 200,027,793 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1200,024,056 - 200,025,466 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1208,405,105 - 208,408,963 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01215,491,358 - 215,495,214 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01208,165,562 - 208,169,418 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01218,024,537 - 218,029,539 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1218,025,810 - 218,027,220 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01224,895,162 - 224,896,687 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41205,292,272 - 205,293,705 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11205,445,724 - 205,447,158 (+)NCBI
Celera1197,582,129 - 197,583,539 (+)NCBICelera
Cytogenetic Map1q42NCBI
FGF4
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381169,771,022 - 69,775,341 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1169,771,022 - 69,775,341 (-)EnsemblGRCh38hg38GRCh38
GRCh371169,585,790 - 69,590,109 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361169,296,978 - 69,299,352 (-)NCBINCBI36Build 36hg18NCBI36
Build 341169,296,977 - 69,299,352NCBI
Celera1166,884,811 - 66,887,185 (-)NCBICelera
Cytogenetic Map11q13.3NCBI
HuRef1165,880,131 - 65,882,505 (-)NCBIHuRef
CHM1_11169,470,729 - 69,473,103 (-)NCBICHM1_1
T2T-CHM13v2.01169,787,944 - 69,792,263 (-)NCBIT2T-CHM13v2.0
Fgf4
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm397144,415,123 - 144,418,982 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl7144,401,104 - 144,418,980 (+)EnsemblGRCm39 Ensembl
GRCm387144,861,386 - 144,865,245 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl7144,847,367 - 144,865,243 (+)EnsemblGRCm38mm10GRCm38
MGSCv377152,047,291 - 152,051,148 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv367144,670,776 - 144,674,633 (+)NCBIMGSCv36mm8
Celera7144,626,624 - 144,630,481 (+)NCBICelera
Cytogenetic Map7F5NCBI
cM Map788.88NCBI
Fgf4
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_00495542216,362,418 - 16,364,126 (+)NCBIChiLan1.0ChiLan1.0
FGF4
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2970,736,483 - 70,740,546 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11171,779,631 - 71,783,694 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01164,866,649 - 64,871,031 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11168,158,485 - 68,196,616 (-)NCBIpanpan1.1PanPan1.1panPan2
FGF4
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11848,413,480 - 48,417,494 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1848,413,187 - 48,416,977 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1847,023,493 - 47,027,360 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01849,090,454 - 49,093,840 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1849,090,383 - 49,093,914 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11848,537,232 - 48,541,095 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01848,123,673 - 48,127,013 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01848,869,443 - 48,873,311 (+)NCBIUU_Cfam_GSD_1.0
Fgf4
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244049474,451,742 - 4,453,375 (+)NCBIHiC_Itri_2
SpeTri2.0NW_004936599894,091 - 895,676 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
FGF4
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl23,526,914 - 3,529,874 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.123,527,113 - 3,529,011 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.222,004,484 - 2,006,245 (+)NCBISscrofa10.2Sscrofa10.2susScr3
FGF4
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.114,786,296 - 4,791,441 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl14,789,203 - 4,791,036 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666038102,062,579 - 102,067,196 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Fgf4
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462476717,381,791 - 17,383,468 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462476717,381,387 - 17,385,698 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

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Variants in Fgf4
4 total Variants

Predicted Target Of
Summary Value
Count of predictions:120
Count of miRNA genes:103
Interacting mature miRNAs:115
Transcripts:ENSRNOT00000028355
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


1 to 10 of 92 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
1578778Pur4Proteinuria QTL 43.30.003urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)1150700247252085048Rat
1354646Kidm18Kidney mass QTL 185.7kidney mass (VT:0002707)calculated kidney weight (CMO:0000160)1151162512256448636Rat
1357335Bw39Body weight QTL 393.3body mass (VT:0001259)body weight (CMO:0000012)1197814409242814409Rat
1578780Cm52Cardiac mass QTL 523.30.0001heart mass (VT:0007028)heart wet weight (CMO:0000069)181591954219808434Rat
2302375Bw83Body weight QTL 834.870.0002body mass (VT:0001259)body weight (CMO:0000012)1197697768242697768Rat
1354652Kidm20Kidney mass QTL 204.3kidney mass (VT:0002707)calculated kidney weight (CMO:0000160)1177227632256448636Rat
2302378Insul11Insulin level QTL 113.25blood insulin amount (VT:0001560)serum insulin level (CMO:0000358)1144267353251128347Rat
1354653Despr9Despair related QTL 90.00019locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)1167909849212909849Rat
2293673Bss27Bone structure and strength QTL 2718.630.0001femur morphology trait (VT:0000559)femur midshaft cortical cross-sectional area (CMO:0001663)1171629477216629477Rat
2293677Bss41Bone structure and strength QTL 419.380.0001lumbar vertebra size trait (VT:0010518)lumbar vertebra cross-sectional area (CMO:0001689)1171629477216629477Rat

1 to 10 of 92 rows
Fgf4  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21200,024,265 - 200,025,443 (+)MAPPERmRatBN7.2
Rnor_6.01218,026,020 - 218,027,197NCBIRnor6.0
Rnor_5.01224,895,406 - 224,896,583UniSTSRnor5.0
RGSC_v3.41205,292,482 - 205,293,682UniSTSRGSC3.4
Celera1197,582,339 - 197,583,516UniSTS
Cytogenetic Map1q42UniSTS
UniSTS:464785  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21200,024,838 - 200,025,411 (+)MAPPERmRatBN7.2
Rnor_6.01218,026,593 - 218,027,165NCBIRnor6.0
Rnor_5.01224,895,979 - 224,896,551UniSTSRnor5.0
RGSC_v3.41205,293,078 - 205,293,650UniSTSRGSC3.4
Celera1197,582,912 - 197,583,484UniSTS
Cytogenetic Map1q42UniSTS
Fgf4  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21200,024,301 - 200,025,448 (+)MAPPERmRatBN7.2
Rnor_6.01218,026,056 - 218,027,202NCBIRnor6.0
Rnor_5.01224,895,442 - 224,896,588UniSTSRnor5.0
RGSC_v3.41205,292,518 - 205,293,687UniSTSRGSC3.4
Celera1197,582,375 - 197,583,521UniSTS
Cytogenetic Map1q42UniSTS




alimentary part of gastrointestinal system
appendage
ectoderm
endocrine system
endoderm
hemolymphoid system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
5 3 4 9 13 3 3 17 5 1 4 17 13



Ensembl Acc Id: ENSRNOT00000028355   ⟹   ENSRNOP00000028355
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1200,024,056 - 200,025,466 (+)Ensembl
Rnor_6.0 Ensembl1218,025,810 - 218,027,220 (+)Ensembl
RefSeq Acc Id: NM_001389212   ⟹   NP_001376141
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81209,453,229 - 209,457,085 (+)NCBI
mRatBN7.21200,023,937 - 200,027,793 (+)NCBI
Protein RefSeqs NP_001376141 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAF70374 (Get FASTA)   NCBI Sequence Viewer  
  BAB84703 (Get FASTA)   NCBI Sequence Viewer  
  EDM12255 (Get FASTA)   NCBI Sequence Viewer  
  EDM12256 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000028355.6
  ENSRNOP00000109820
GenBank Protein VDK10964 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Acc Id: ENSRNOP00000028355   ⟸   ENSRNOT00000028355
RefSeq Acc Id: NP_001376141   ⟸   NM_001389212
- Peptide Label: precursor
- UniProtKB: A0A7U3L6A6 (UniProtKB/TrEMBL),   F1LSQ8 (UniProtKB/TrEMBL),   Q8R5L6 (UniProtKB/TrEMBL)

Name Modeler Protein Id AA Range Protein Structure
AF-F1LSQ8-F1-model_v2 AlphaFold F1LSQ8 1-194 view protein structure


eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen



1 to 25 of 25 rows
Database
Acc Id
Source(s)
BioCyc Gene G2FUF-56842 BioCyc
Ensembl Genes ENSRNOG00000020890 Ensembl, UniProtKB/TrEMBL
  ENSRNOG00000083188 ENTREZGENE
Ensembl Transcript ENSRNOT00000028355.6 UniProtKB/TrEMBL
  ENSRNOT00000168129 ENTREZGENE
Gene3D-CATH 2.80.10.50 UniProtKB/TrEMBL
InterPro Cytokine_IL1-like UniProtKB/TrEMBL
  GF_heparin-bd UniProtKB/TrEMBL
NCBI Gene 116499 ENTREZGENE
PANTHER IL1_HBGF UniProtKB/TrEMBL
Pfam FGF UniProtKB/TrEMBL
PhenoGen Fgf4 PhenoGen
PRINTS HBGFFGF UniProtKB/TrEMBL
  IL1HBGF UniProtKB/TrEMBL
PROSITE HBGF_FGF UniProtKB/TrEMBL
RatGTEx ENSRNOG00000020890 RatGTEx
  ENSRNOG00000083188 RatGTEx
SMART FGF UniProtKB/TrEMBL
Superfamily-SCOP Cytok_IL1_like UniProtKB/TrEMBL
UniProt A0A7U3L6A6 ENTREZGENE
  A6HYH4_RAT UniProtKB/TrEMBL
  A6HYH5_RAT UniProtKB/TrEMBL
  F1LSQ8 ENTREZGENE, UniProtKB/TrEMBL
  Q8R5L6 ENTREZGENE, UniProtKB/TrEMBL
UniProt Secondary A0A7U3L6A6 UniProtKB/TrEMBL
1 to 25 of 25 rows


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2005-01-20 Fgf4  fibroblast growth factor 4      Symbol and Name status set to approved 1299863 APPROVED
2002-08-07 Fgf4  fibroblast growth factor 4      Symbol and Name status set to provisional 70820 PROVISIONAL