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Gene: Slc24a1 (solute carrier family 24 member 1) Rattus norvegicus

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Symbol:

Slc24a1

Name:

solute carrier family 24 member 1

RGD ID:

620080

Description:

Predicted to enable calcium channel activity and calcium, potassium:sodium antiporter activity. Involved in calcium ion transmembrane transport. Located in cell surface. Human ortholog(s) of this gene implicated in congenital stationary night blindness 1D. Orthologous to human SLC24A1 (solute carrier family 24 member 1); PARTICIPATES IN calcium transport pathway; calcium/calcium-mediated signaling pathway; visual phototransduction pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; bisphenol A.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

na(+)/K(+)/Ca(2+)-exchange protein 1; Nckx1; retinal Na/Ca,K exchanger; retinal rod Na-Ca+K exchanger; sodium/calcium/potassium exchanger; sodium/potassium/calcium exchanger 1; solute carrier family 24 (sodium/potassium/calcium exchanger), member 1

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	8	74,334,556 - 74,361,313 (-)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	8	74,335,053 - 74,361,268 (-)	Ensembl				GRCr8
mRatBN7.2	8	65,440,842 - 65,466,001 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	8	65,440,730 - 65,466,001 (-)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	8	70,953,820 - 70,978,673 (-)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	8	69,226,409 - 69,251,675 (-)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	8	67,096,411 - 67,121,221 (-)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	8	70,409,683 - 70,438,352 (-)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	8	70,408,528 - 70,436,028 (-)	Ensembl			rn6	Rnor6.0
Rnor_5.0	8	70,111,171 - 70,136,142 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	8	69,175,549 - 69,208,432 (-)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	8	64,843,360 - 64,868,623 (-)	NCBI		Celera
RGSC_v3.1	8	69,194,602 - 69,227,483 (-)	NCBI
Cytogenetic Map	8	q24	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Cerebral Hemorrhage (IEP)

congenital stationary night blindness (ISO)

congenital stationary night blindness 1D (ISO,ISS)

congenital stationary night blindness autosomal dominant 2 (ISO)

fundus dystrophy (ISO)

genetic disease (ISO)

retinitis pigmentosa (ISO)

retinitis pigmentosa 1 (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

2,3,7,8-tetrachlorodibenzodioxine (EXP)

6-propyl-2-thiouracil (EXP)

acrolein (ISO)

aflatoxin B1 (ISO)

alpha-pinene (ISO)

benzo[a]pyrene (ISO)

bisphenol A (EXP)

butanal (ISO)

cisplatin (ISO)

copper atom (EXP)

copper(0) (EXP)

copper(II) sulfate (ISO)

dichloroacetic acid (ISO)

dicrotophos (ISO)

doxorubicin (ISO)

flavonoids (EXP)

folic acid (ISO)

okadaic acid (ISO)

ozone (ISO)

paracetamol (ISO)

pentanal (ISO)

resveratrol (ISO)

silicon dioxide (ISO)

sunitinib (ISO)

thiram (ISO)

titanium dioxide (ISO)

triphenyl phosphate (ISO)

urethane (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

calcium ion transmembrane transport (IBA,IDA,IEA,ISO)

calcium ion transport (IEA)

intracellular calcium ion homeostasis (IBA,ISO)

long-term synaptic depression (IBA)

long-term synaptic potentiation (IBA)

monoatomic ion transport (IEA)

potassium ion transmembrane transport (IEA,ISO)

sodium ion transmembrane transport (IEA,ISO)

transmembrane transport (IEA)

visual perception (IEA)

Cellular Component

cell surface (IDA)

membrane (IEA)

plasma membrane (IBA,IEA,ISO)

Molecular Function

antiporter activity (IEA)

calcium channel activity (IBA)

calcium, potassium:sodium antiporter activity (IBA,IEA,ISO)

protein binding (ISO)

symporter activity (IEA)

Molecular Pathway Annotations Click to see Annotation Detail View

calcium transport pathway (ISO)

calcium/calcium-mediated signaling pathway (ISO)

visual phototransduction pathway (IEA,ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Na+/Ca2+-K+ exchangers (NCKX): functional properties and physiological roles.	Altimimi HF and Schnetkamp PP, Channels (Austin). 2007 Mar-Apr;1(2):62-9. Epub 2007 Apr 30.
2.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3.	Rat ISS GO annotations from GOA human gene data--August 2006	GOA data from the GO Consortium
4.	Differential expression of Na/Ca exchanger and Na/Ca + K exchanger transcripts in rat brain.	Li XF and Lytton J, Ann N Y Acad Sci 2002 Nov;976:64-6.
5.	Na+/Ca2+ exchangers: three mammalian gene families control Ca2+ transport.	Lytton J Biochem J. 2007 Sep 15;406(3):365-82.
6.	Rat ISS GO annotations from MGI mouse gene data--August 2006	MGD data from the GO Consortium
7.	Electronic Transfer of LocusLink and RefSeq Data	NCBI rat LocusLink and RefSeq merged data July 26, 2002
8.	OMIM Disease Annotation Pipeline	OMIM Disease Annotation Pipeline
9.	KEGG Annotation Import Pipeline	Pipeline to import KEGG annotations from KEGG into RGD
10.	Alternatively spliced isoforms of the rat eye sodium/calcium+potassium exchanger NCKX1.	Poon S, etal., Am J Physiol Cell Physiol. 2000 Apr;278(4):C651-60.
11.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
12.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
13.	Alteration of intracellular calcium and its modulator SLC24A6 after experimental intracerebral hemorrhage.	Zheng M, etal., Acta Neurochir Suppl. 2013;118:169-73. doi: 10.1007/978-3-7091-1434-6_31.

Additional References at PubMed

PMID:26631410

Genomics

Comparative Map Data

Slc24a1
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	8	74,334,556 - 74,361,313 (-)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	8	74,335,053 - 74,361,268 (-)	Ensembl				GRCr8
mRatBN7.2	8	65,440,842 - 65,466,001 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	8	65,440,730 - 65,466,001 (-)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	8	70,953,820 - 70,978,673 (-)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	8	69,226,409 - 69,251,675 (-)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	8	67,096,411 - 67,121,221 (-)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	8	70,409,683 - 70,438,352 (-)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	8	70,408,528 - 70,436,028 (-)	Ensembl			rn6	Rnor6.0
Rnor_5.0	8	70,111,171 - 70,136,142 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	8	69,175,549 - 69,208,432 (-)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	8	64,843,360 - 64,868,623 (-)	NCBI		Celera
RGSC_v3.1	8	69,194,602 - 69,227,483 (-)	NCBI
Cytogenetic Map	8	q24	NCBI

SLC24A1
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	15	65,611,350 - 65,661,002 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	15	65,611,366 - 65,660,995 (+)	Ensembl			hg38	GRCh38
GRCh37	15	65,903,688 - 65,953,340 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	15	63,701,323 - 63,735,652 (+)	NCBI	Build 36	Build 36	hg18	NCBI36
Build 34	15	63,701,322 - 63,735,260	NCBI
Celera	15	42,792,100 - 42,826,427 (+)	NCBI		Celera
Cytogenetic Map	15	q22.31	NCBI
HuRef	15	42,738,496 - 42,772,472 (+)	NCBI		HuRef
CHM1_1	15	66,031,979 - 66,066,318 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	15	63,420,643 - 63,470,640 (+)	NCBI		T2T-CHM13v2.0

Slc24a1
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	9	64,830,143 - 64,858,902 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	9	64,830,143 - 64,858,889 (-)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	9	64,922,861 - 64,951,620 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	9	64,922,861 - 64,951,607 (-)	Ensembl			mm10	GRCm38
MGSCv37	9	64,770,668 - 64,799,414 (-)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	9	64,720,867 - 64,749,613 (-)	NCBI		MGSCv36	mm8
Celera	9	62,153,368 - 62,182,148 (-)	NCBI		Celera
Cytogenetic Map	9	C	NCBI
cM Map	9	35.0	NCBI

Slc24a1
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955450	9,856,718 - 9,881,172 (-)	Ensembl
ChiLan1.0	NW_004955450	9,850,170 - 9,881,172 (-)	NCBI	ChiLan1.0	ChiLan1.0

SLC24A1
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	16	54,859,732 - 54,904,439 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	15	59,031,935 - 59,075,520 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	15	44,552,886 - 44,597,640 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	15	62,831,987 - 62,882,805 (+)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	15	62,831,987 - 62,882,431 (+)	Ensembl			panPan2	panpan1.1

SLC24A1
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	30	29,967,762 - 29,996,762 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	30	29,967,762 - 29,995,005 (+)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	30	29,895,465 - 29,924,529 (+)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	30	30,157,940 - 30,187,034 (+)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	30	30,157,940 - 30,185,283 (+)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	30	30,087,715 - 30,116,960 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	30	30,150,083 - 30,178,950 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	30	30,390,877 - 30,419,972 (+)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Slc24a1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024408640	108,018,445 - 108,061,086 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936471	25,872,423 - 25,908,158 (+)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936471	25,872,854 - 25,909,102 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

SLC24A1
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	1	163,604,594 - 163,658,318 (+)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	1	163,603,223 - 163,662,071 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	1	181,291,339 - 181,302,513 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

SLC24A1
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	26	17,924,872 - 17,969,413 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	26	17,923,872 - 17,956,668 (-)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM
Vero_WHO_p1.0	NW_023666048	123,472,543 - 123,516,955 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Slc24a1
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624781	6,935,239 - 6,974,196 (-)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
HetGla 1.0	NW_004624781	6,934,108 - 6,957,632 (-)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Slc24a1
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	8	59,223,173 - 59,255,199 (-)	NCBI		Rrattus_CSIRO_v1

Variants

Variants in Slc24a1
235 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	154
Count of miRNA genes:	50
Interacting mature miRNAs:	50
Transcripts:	ENSRNOT00000038156, ENSRNOT00000045430, ENSRNOT00000055087, ENSRNOT00000055093
Prediction methods:	Microtar, Miranda, Rnahybrid
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1298065	Scl16	Serum cholesterol level QTL 16	3.8		blood cholesterol amount (VT:0000180)	plasma total cholesterol level (CMO:0000585)	8	39752803	84752803	Rat
1554321	Bmd3	Bone mineral density QTL 3	7.9	0.0001	femur mineral mass (VT:0010011)	volumetric bone mineral density (CMO:0001553)	8	49849908	118871671	Rat
1578769	Uae31	Urinary albumin excretion QTL 31	3.3	0.001	urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	8	39106363	103375781	Rat
1298079	Activ2	Activity QTL 2	9.5	0.000001	voluntary movement trait (VT:0003491)	rearing measurement (CMO:0001515)	8	50763951	95763951	Rat
11556286	Cm81	Cardiac mass QTL 81		0.01	heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	8	39106258	84106258	Rat
70161	Bp62	Blood pressure QTL 62	2.9	0.001	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	8	51589699	99045312	Rat
1578765	Klgr1	Kidney lesion grade QTL 1	3.3	0.0001	kidney morphology trait (VT:0002135)	organ lesion measurement (CMO:0000677)	8	39106363	103375781	Rat
61464	Niddm11	Non-insulin dependent diabetes mellitus QTL 11	3.1	0.001	blood insulin amount (VT:0001560)	plasma insulin level (CMO:0000342)	8	44477926	89477926	Rat
4889938	Bss89	Bone structure and strength QTL 89	3.8		tibia size trait (VT:0100001)	tibia cortical bone volume (CMO:0001725)	8	58991697	91341052	Rat
1578755	Pur5	Proteinuria QTL 5	3.3	0.0001	urine total protein amount (VT:0000032)	urine total protein excretion rate (CMO:0000756)	8	39106258	103375958	Rat
631210	Bw3	Body weight QTL3	5.9		mesenteric fat pad mass (VT:0010427)	mesenteric fat pad weight to body weight ratio (CMO:0000654)	8	61019838	121662124	Rat
2313088	Bss75	Bone structure and strength QTL 75	3.1	0.0001	body length (VT:0001256)	body length, nose to rump (CMO:0000079)	8	39106258	91341052	Rat
8662823	Vetf5	Vascular elastic tissue fragility QTL 5	1.9		artery integrity trait (VT:0010639)	patent ductus arteriosus score (CMO:0002566)	8	63404444	108404444	Rat
1358896	Bp262	Blood pressure QTL 262	2.89		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	8	35464071	107982864	Rat
731182	Uae24	Urinary albumin excretion QTL 24	6.4		urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	8	47541419	92541419	Rat
61353	Bp35	Blood pressure QTL 35		0.001	arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	8	39106258	84106258	Rat
631842	Inf1	Infertility severity QTL 1	4.1	0.001	seminal gland mass (VT:0010524)	seminal vesicle wet weight (CMO:0001603)	8	31543661	76543661	Rat
1331769	Rf39	Renal function QTL 39	3.871		urine output (VT:0003620)	timed urine volume (CMO:0000260)	8	50763951	107970527	Rat
1359033	Bp273	Blood pressure QTL 273			arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	8	39106258	84106258	Rat
1358906	Bp253	Blood pressure QTL 253	4	0.0004	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	8	49610204	94610204	Rat
61358	Bp39	Blood pressure QTL 39	2		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	8	44447837	89447837	Rat
1358907	Cm40	Cardiac mass QTL 40	1.89		heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	8	35464071	107982864	Rat
70197	BpQTLcluster8	Blood pressure QTL cluster 8	3.482		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	8	55428333	127966348	Rat
2316950	Scl66	Serum cholesterol level QTL 66	4.1		blood cholesterol amount (VT:0000180)	plasma total cholesterol level (CMO:0000585)	8	39106363	114525825	Rat
1582254	Kidm31	Kidney mass QTL 31	3		kidney mass (VT:0002707)	both kidneys wet weight (CMO:0000085)	8	49245178	94245178	Rat
724540	Uae8	Urinary albumin excretion QTL 8	5		urine albumin amount (VT:0002871)	urine albumin level (CMO:0000130)	8	39106258	103375958	Rat
10402857	Bp380	Blood pressure QTL 380		0.95	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	8	62848139	107848139	Rat
1358892	Kidm26	Kidney mass QTL 26	3.69		kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	8	35464071	107982864	Rat
1582243	Bw66	Body weight QTL 66	3.4	0.0048	body mass (VT:0001259)	body weight (CMO:0000012)	8	49245178	94245178	Rat
5684973	Bss100	Bone structure and strength QTL 100	4.7		tibia area (VT:1000281)	tibia area measurement (CMO:0001382)	8	58991697	91341052	Rat
61373	Mcs4	Mammary carcinoma susceptibility QTL 4	1.1		mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	8	44475043	89475043	Rat
1300177	Cm2	Cardiac mass QTL 2	3.65		heart mass (VT:0007028)	heart weight (CMO:0000017)	8	63141536	109261840	Rat
2313057	Bss76	Bone structure and strength QTL 76	3	0.0001	tibia size trait (VT:0100001)	tibia midshaft cross-sectional area (CMO:0001717)	8	39106258	91341052	Rat
12879878	Bw183	Body weight QTL 183		0.001	body mass (VT:0001259)	body weight (CMO:0000012)	8	62848139	107848139	Rat
1549908	Neudeg1	Neurodegradation QTL 1	5.5	0	nervous system integrity trait (VT:0010566)	logarithm of the ratio of the lesioned side motor neuron count to contralateral side motor neuron count (CMO:0001986)	8	58337123	103337123	Rat
12879879	Cm99	Cardiac mass QTL 99		0.001	heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	8	62848139	107848139	Rat
1331804	Cm30	Cardiac mass QTL 30	3.77443		heart mass (VT:0007028)	heart wet weight (CMO:0000069)	8	62970527	107970527	Rat
2313067	Bss77	Bone structure and strength QTL 77	3.1	0.0001	tibia size trait (VT:0100001)	tibia midshaft endosteal cross-sectional area (CMO:0001716)	8	39106258	91341052	Rat
12879880	Cm100	Cardiac mass QTL 100		0.001	heart left ventricle mass (VT:0007031)	heart left ventricle weight to body weight ratio (CMO:0000530)	8	62848139	107848139	Rat
12879881	Cm101	Cardiac mass QTL 101		0.001	heart right ventricle mass (VT:0007033)	heart right ventricle weight to body weight ratio (CMO:0000914)	8	62848139	107848139	Rat
12879882	Am8	Aortic mass QTL 8		0.001	aorta mass (VT:0002845)	aorta weight to aorta length to body weight ratio (CMO:0002722)	8	62848139	107848139	Rat
12879883	Kidm65	Kidney mass QTL 65		0.001	kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	8	62848139	107848139	Rat
71120	Niddm21	Non-insulin dependent diabetes mellitus QTL 21	3.73		blood glucose amount (VT:0000188)	plasma glucose level (CMO:0000042)	8	66992095	111992095	Rat
1358912	Bw51	Body weight QTL 51	2.95		body mass (VT:0001259)	body weight (CMO:0000012)	8	60248093	105248093	Rat
2313086	Bss60	Bone structure and strength QTL 60	4.1	0.0001	tibia length (VT:0004357)	tibia length (CMO:0000450)	8	58991697	91341052	Rat
2293697	Bmd39	Bone mineral density QTL 39			femur strength trait (VT:0010010)	femur total energy absorbed before break (CMO:0001677)	8	62848139	107848139	Rat
1331837	Bw23	Body weight QTL 23	4.19	0.00007	body mass (VT:0001259)	body weight (CMO:0000012)	8	55428416	107963099	Rat
1331838	Niddm61	Non-insulin dependent diabetes mellitus QTL 61	3.53	0.0004	blood insulin amount (VT:0001560)	plasma insulin level (CMO:0000342)	8	62963099	107963099	Rat
631650	Stl6	Serum triglyceride level QTL 6	4	0.0019	blood triglyceride amount (VT:0002644)	plasma triglyceride level (CMO:0000548)	8	70041301	121080908	Rat
1581557	Eae16	Experimental allergic encephalomyelitis QTL 16	3.8		nervous system integrity trait (VT:0010566)	experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)	8	68690349	119799881	Rat
2313046	Bss78	Bone structure and strength QTL 78	3.5	0.0001	tibia strength trait (VT:1000284)	tibia total energy absorbed before break (CMO:0001736)	8	39106258	91341052	Rat
631664	Hcar3	Hepatocarcinoma resistance QTL 3	2.9	0.0005	liver integrity trait (VT:0010547)	volume of individual liver tumorous lesion (CMO:0001078)	8	62982864	107982864	Rat
2301402	Bp316	Blood pressure QTL 316		0.005	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	8	62848139	107848139	Rat

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
11	12	64	153	80	79	48	79	48	6	313	176	10	132	70	91	31	17	17

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_020090	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017595873	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063266044	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC107597	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AF176688	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000008	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	U49235	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000077152 ⟹ ENSRNOP00000074571

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	8	74,335,053 - 74,361,207 (-)	Ensembl
mRatBN7.2 Ensembl	8	65,440,730 - 65,466,001 (-)	Ensembl
Rnor_6.0 Ensembl	8	70,408,528 - 70,436,028 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000100509 ⟹ ENSRNOP00000087860

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	8	74,335,053 - 74,361,268 (-)	Ensembl
mRatBN7.2 Ensembl	8	65,440,730 - 65,466,001 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000101835 ⟹ ENSRNOP00000091100

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	8	74,335,053 - 74,361,268 (-)	Ensembl
mRatBN7.2 Ensembl	8	65,440,730 - 65,465,997 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000116039 ⟹ ENSRNOP00000087726

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	8	74,335,053 - 74,361,207 (-)	Ensembl
mRatBN7.2 Ensembl	8	65,440,730 - 65,466,001 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000130614 ⟹ ENSRNOP00000102934

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	8	74,335,053 - 74,361,268 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000149459 ⟹ ENSRNOP00000103692

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	8	74,335,053 - 74,361,268 (-)	Ensembl

RefSeq Acc Id:

NM_020090 ⟹ NP_064475

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	8	74,336,054 - 74,361,207 (-)	NCBI
mRatBN7.2	8	65,440,842 - 65,466,001 (-)	NCBI
Rnor_6.0	8	70,411,186 - 70,436,337 (-)	NCBI
Rnor_5.0	8	70,111,171 - 70,136,142 (-)	NCBI
RGSC_v3.4	8	69,175,549 - 69,208,432 (-)	RGD
Celera	8	64,843,360 - 64,868,623 (-)	RGD

Sequence:

show sequence

CACCATGGGGAAATTGATCAGGATGGGGACGCAGGAGAGGCGGTTACTCCGACCAAAGAGGCTT
CATTGGAGTCGCCTCCTTTTCTTCCTGGGAATGTTGATCATTGGTTCCACTTATCAGCACCTGA
GGAGACCCCAGAATCCCCCTTCAATGTGGACAAAAGTCTCCTCACAGCAGCCTATTAAACTGGC
CATCAGGGACCTCCCCAATGATGAGATAACAGTGACAGACAAAGACCCTCCAGAGGCTAGCTCT
GAAGTGGAGGGTGAGATGCTAGCACCCCAAGACACAGTGATCATAGGTGAAGCAGCACCTAGCA
TAGCAATGGAGGACACCCCCAATCCACCCATAACAACCAAGATCACTCCAACGTCACTAAAGAA
CAATTATAGCCCCACAACAGCTGGCACGAGGAGACAAAAAGAAAACATTCCACCCACACCTAGC
AGAGCACCGAGTCACTTCATCTCAACTTCAGGCAGACAGAGAGTGAAAAGCTATACCCCAAAAC
CCAGGGGAGGAAGGAAGAGCTCCAGCCCAACTCACACCAGGGAAGAAGGAAGGATGCATACCCC
ATCCCCAGCAGGTGCGCCCCGCACCATCAGCCCCACATCAACAGAGAAAGACAGTGAAACCACG
GCAACCTATAGGATGTTGGAGCCCAGATCTGAGAGAACAGCAGGAAAAACTTCTCTCAAGAGAA
TGGTTCCGAACACCCGGACTTTCTTAACACGCGAAGTAGAAACAGACCTCGTGACTTCTCCAAG
TTTGGTGGGGAAGAACACCCTGGGAAGTCCTAGAAGAGGAGAAAGAAACAGCTCTACCACTCCC
CTGCGAGCAGTCCTGCAGCCTACCCCTGCCACCTCTGAGGAGCAAGTGACGGCAAGCATCAGGA
TGGGTAGCACCCCAGCAACCACTGAAGGTTCTACTGCTGCCCAGAGAATTGGCAATCCCTTGTC
CGGAACTAGTACACCAGCTGTTAGAATTGCCTCAGTCACGGACAGGGAAAAGAGACCTTCCACA
GCACACGGCACCCTAGTAACTCCCCAAGTCAAGGCAGTCCTGACCACACAGGTCCACCGCTGTG
TGGTTGTGAAGCCAGCCCCAGCTGTACCCATGACCCCATCTCCGAGCATGACAGCCATCCTGTT
CCCAGAGGCACCTACTTCCGGTCCCTCAGCCTTGCCGCCTGGCTGGCCAAACCTCCACCCCAAG
GCGGAGTATCCCCCAGACCTGTTCAGTGTGGAGGATCGACGCCAGGGCTGGGTGGTCCTACACA
TCTTCGGTATGACGTACGTGTTTGTGGCCTTGGCCATCGTGTGTGATGAGTACTTTGTCCCAGC
CCTGGGGGTCATCACGGACAAGCTTCAGATCTCCGAGGATGTGGCCGGGGCCACATTCATGGCT
GCCGGAGGCTCAGCCCCTGAGCTCTTCACCTCTCTCATTGGTGTCTTTATCTCCCATAGCAATG
TGGGTATTGGTACCATCGTGGGCTCTGCTGTGTTCAACATCCTTTTTGTCATCGGCACCTGCGC
CCTCTTCTCCCGGGAGATCCTCAACCTCACCTGGTGGCCCCTGTTCCGAGATGTCTCCTTCTAC
ATCCTTGACTTGTCTATGCTCATAGTCTTTTTCCTGGATAGTCTCATTGCCTGGTGGGAGAGCC
TGCTGCTGCTGCTGGCCTACGCTCTCTATGTGTTCACCATGAAGTGGAACAAGCAGATTGAACG
CTGGGTGAAAGAGCAGCTTAGCAGGAGGCCAGTAGCCAAAGTCATGGCTCTAGGAGACCTCAGC
AAGCCCAGTGATGGTGCCATTGAGGAAAATGAACAACAGGATAACAAGAAGCTGAAGCTCCCGT
CTGTGCTGACCCGAGGGAGCAGCTCGGCCTCCCTGCACAACAGCATCATCCGCAGCACCATCTA
CCACCTCATGCTCCACAGCTTGGACCCCCTGGGGGAAGCCCGCCCCTCCAAGGACAAGCAGGAA
AGTTTGAATCAGGAAGCCAGAGTCCTCCCCCAGACCAAAGCAGAAAGCAGCTCAGACGAGGAGG
AGCCAGCCGAGCTCCCTGCGGTCACGGTCACTCCAGCCCCTGCTCCAGAGGACAAGGGAGATCA
GGAGGAGGATCCAGGCTGCCAGGAAGATGTGGATGAGGCTGAACACAGAGGAGACATGACAGGT
GAAGAGGGTGAAAGGGAAACCGAGGCAGAAGGAAAAAAAGATGAAGAAGGGGAAACTGAGGCAG
AAAGGAAAGAAGATGGTCAAGAAGAAGAAACTGAGACAAAAGGGAAAGAGAAACAAGAAGGGGA
AACTGAGTCAGAAGGAAAAGATGAACAAGAAGGGGAAACTGAGGCAGAAGGAAAAGAAGCTGAC
CATGAAGGGGAAACTGAGGCAGAAGGAAAAGAGGTTGAACATGAAGGGGAAACTGAAGCAGAAG
GAACAGAAGATGAACAAGAAGGGGAAACTGAGGCAGAAGGAAAAGAAGTTGAACAAGAAGGGGA
AACTGAGGCAGAAGGAAAAGAAGTTGAACATGAAGTGGAAACTGAGGCAGAAAGAAAAGAAACT
AACCATGAAGGGGAAACTGAGGCAGAAGGAAAAGAAGCTGACCATGAAGGGGAAACAGAGGCAG
AAGGAAATGTTGAACATCAAGGGGAAACTGAGGCAGAAGGAAAAGTTGAACATGAGGGGGAAAC
CGAGGCAGGAGAAAAAGATGAGCATGAAGGGCAAAGTGAGACCCAAGCAGACGACACTGAGGTG
AAAGATGGTGAGGGTGAAGCAGAAGCCAATGCTGAAGATCAATGTGAGACCGCCCAAGGTGAGA
AAGGTGCAGACGGTGGAGGGGGAAGTGATGGAGGGGACAGTGAAGAAGAGGAGGATGAAGAGGA
TGAAGAGGAGGAGGAAGAGGAGGAAGAGGAGGAAGAGGAGGAGGAAAGTGAGGAGCCTCTGTCC
TTGGAATGGCCTGAGAGCAGGCAGAAGCAGGCTATCTACCTCTTTCTCCTGCCCATCGTGTTCC
CACTGTGGCTGACAATACCTGATGTACGGAGGCAGGAGGCCAGGAAGTTTTTTGTCATCACCTT
CCTGGGATCCATCATCTGGATAGCCATGTTCTCATACCTCATGGTGTGGTGGGCTCACCAGGTT
GGTGAAACCATTGGGATTTCTGAAGAGATTATGGGTTTGACGATCCTAGCGGCAGGCACTTCAA
TTCCTGACCTCATCACCAGTGTGATCGTTGCCCGGAAAGGCCTGGGAGACATGGCCGTGTCAAG
CTCGGTGGGCAGTAACATATTTGATATCACAGTGGGCCTGCCTGTCCCCTGGCTCCTGTTCTCC
CTCATCAATGCGCTGCAGCCTATCCCTGTCAGCAGCAACGGCCTGTTCTGTGCCATTGTCTTGC
TGTTTCTCATGCTCCTGTTTGTGATCTTCTCAATCGCTTCGTGTAAATGGAGAATGAACAAGAT
CCTGGGCTTCACCATGTTCCTTCTCTACTTTGTGTTCCTGGTGATCAGTGTGATGTTAGAAGAT
CGCATCATATCCTGCCCTGTATCTGTCTGA

hide sequence

RefSeq Acc Id:

XM_063266044 ⟹ XP_063122114

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	8	74,334,556 - 74,361,313 (-)	NCBI

Protein Sequences


Protein RefSeqs	NP_064475	(Get FASTA)	NCBI Sequence Viewer
	XP_063122114	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAB37753	(Get FASTA)	NCBI Sequence Viewer
	AAD53121	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000074571
	ENSRNOP00000074571.2
	ENSRNOP00000087726.1
	ENSRNOP00000087860.1
	ENSRNOP00000091100
	ENSRNOP00000091100.1
GenBank Protein	Q9QZM6	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

NP_064475 ⟸ NM_020090

- UniProtKB:

Q62932 (UniProtKB/Swiss-Prot), Q9QZM6 (UniProtKB/Swiss-Prot), A0A0G2K8E1 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MGKLIRMGTQERRLLRPKRLHWSRLLFFLGMLIIGSTYQHLRRPQNPPSMWTKVSSQQPIKLAI
RDLPNDEITVTDKDPPEASSEVEGEMLAPQDTVIIGEAAPSIAMEDTPNPPITTKITPTSLKNN
YSPTTAGTRRQKENIPPTPSRAPSHFISTSGRQRVKSYTPKPRGGRKSSSPTHTREEGRMHTPS
PAGAPRTISPTSTEKDSETTATYRMLEPRSERTAGKTSLKRMVPNTRTFLTREVETDLVTSPSL
VGKNTLGSPRRGERNSSTTPLRAVLQPTPATSEEQVTASIRMGSTPATTEGSTAAQRIGNPLSG
TSTPAVRIASVTDREKRPSTAHGTLVTPQVKAVLTTQVHRCVVVKPAPAVPMTPSPSMTAILFP
EAPTSGPSALPPGWPNLHPKAEYPPDLFSVEDRRQGWVVLHIFGMTYVFVALAIVCDEYFVPAL
GVITDKLQISEDVAGATFMAAGGSAPELFTSLIGVFISHSNVGIGTIVGSAVFNILFVIGTCAL
FSREILNLTWWPLFRDVSFYILDLSMLIVFFLDSLIAWWESLLLLLAYALYVFTMKWNKQIERW
VKEQLSRRPVAKVMALGDLSKPSDGAIEENEQQDNKKLKLPSVLTRGSSSASLHNSIIRSTIYH
LMLHSLDPLGEARPSKDKQESLNQEARVLPQTKAESSSDEEEPAELPAVTVTPAPAPEDKGDQE
EDPGCQEDVDEAEHRGDMTGEEGERETEAEGKKDEEGETEAERKEDGQEEETETKGKEKQEGET
ESEGKDEQEGETEAEGKEADHEGETEAEGKEVEHEGETEAEGTEDEQEGETEAEGKEVEQEGET
EAEGKEVEHEVETEAERKETNHEGETEAEGKEADHEGETEAEGNVEHQGETEAEGKVEHEGETE
AGEKDEHEGQSETQADDTEVKDGEGEAEANAEDQCETAQGEKGADGGGGSDGGDSEEEEDEEDE
EEEEEEEEEEEEEESEEPLSLEWPESRQKQAIYLFLLPIVFPLWLTIPDVRRQEARKFFVITFL
GSIIWIAMFSYLMVWWAHQVGETIGISEEIMGLTILAAGTSIPDLITSVIVARKGLGDMAVSSS
VGSNIFDITVGLPVPWLLFSLINALQPIPVSSNGLFCAIVLLFLMLLFVIFSIASCKWRMNKIL
GFTMFLLYFVFLVISVMLEDRIISCPVSV

hide sequence

Ensembl Acc Id:

ENSRNOP00000074571 ⟸ ENSRNOT00000077152

Ensembl Acc Id:

ENSRNOP00000087860 ⟸ ENSRNOT00000100509

Ensembl Acc Id:

ENSRNOP00000087726 ⟸ ENSRNOT00000116039

Ensembl Acc Id:

ENSRNOP00000091100 ⟸ ENSRNOT00000101835

RefSeq Acc Id:	XP_063122114 ⟸ XM_063266044
- Peptide Label:	isoform X1
- UniProtKB:	A0A0G2K8E1 (UniProtKB/TrEMBL)

Ensembl Acc Id:

ENSRNOP00000102934 ⟸ ENSRNOT00000130614

Ensembl Acc Id:

ENSRNOP00000103692 ⟸ ENSRNOT00000149459

Protein Domains

Sodium/calcium exchanger membrane region

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q9QZM6-F1-model_v2	AlphaFold	Q9QZM6	1-1181	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:620080	AgrOrtholog
BioCyc Gene	G2FUF-30082	BioCyc
Ensembl Genes	ENSRNOG00000052051	Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript	ENSRNOT00000077152	ENTREZGENE
	ENSRNOT00000077152.2	UniProtKB/Swiss-Prot
	ENSRNOT00000100509.1	UniProtKB/Swiss-Prot
	ENSRNOT00000101835	ENTREZGENE
	ENSRNOT00000101835.1	UniProtKB/Swiss-Prot
	ENSRNOT00000116039.1	UniProtKB/Swiss-Prot
Gene3D-CATH	1.20.1420.30	UniProtKB/Swiss-Prot
InterPro	K/Na/Ca-exchanger	UniProtKB/Swiss-Prot
	NaCa_Exmemb	UniProtKB/Swiss-Prot
	NCX_ion-bd_dom_sf	UniProtKB/Swiss-Prot
	SLC24A1	UniProtKB/Swiss-Prot
KEGG Report	rno:56814	UniProtKB/Swiss-Prot
NCBI Gene	56814	ENTREZGENE
PANTHER	PTHR10846	UniProtKB/Swiss-Prot
	SODIUM/POTASSIUM/CALCIUM EXCHANGER 1	UniProtKB/Swiss-Prot
Pfam	Na_Ca_ex	UniProtKB/Swiss-Prot
PhenoGen	Slc24a1	PhenoGen
RatGTEx	ENSRNOG00000052051	RatGTEx
UniProt	A0A0G2K8E1	ENTREZGENE, UniProtKB/TrEMBL
	A0ABK0LMK5_RAT	UniProtKB/TrEMBL
	A0ABK0LT17_RAT	UniProtKB/TrEMBL
	NCKX1_RAT	UniProtKB/Swiss-Prot
	Q62932	ENTREZGENE
	Q9QZM6	ENTREZGENE
UniProt Secondary	Q62932	UniProtKB/Swiss-Prot

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2016-03-09	Slc24a1	solute carrier family 24 member 1	Slc24a1	solute carrier family 24 (sodium/potassium/calcium exchanger), member 1	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-01-09	Slc24a1	solute carrier family 24 (sodium/potassium/calcium exchanger), member 1	LOC678758	hypothetical protein LOC678758	Data merged from RGD:1596926	1643240	APPROVED
2006-11-20	LOC678758	hypothetical protein LOC678758			Symbol and Name status set to provisional	70820	PROVISIONAL
2004-09-10	Slc24a1	solute carrier family 24 (sodium/potassium/calcium exchanger), member 1		sodium/calcium/potassium exchanger	Name updated	1299863	APPROVED
2002-08-07	Slc24a1	sodium/calcium/potassium exchanger			Symbol and Name status set to provisional	70820	PROVISIONAL

RGD Curation Notes

Note Type	Note	Reference
gene_expression	highly expressed in the brain	634213

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - MGI

Imported Disease Annotations - OMIM

RGD Manual Annotations

Imported Annotations - KEGG (archival)

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Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - MGI

Imported Disease Annotations - OMIM

RGD Manual Annotations

Imported Annotations - KEGG (archival)