Gene:	Ihh ( Rattus norvegicus ) Indian hedgehog
Description:	member of the hedgehog family of secreted morphogens; regulates chondrocyte (cartilage cell) differentiation
Synonyms:	indian hedgehog homolog, (drosophila); Indian hedgehog homolog, (Drosophila);
ArrayIDs:	A_44_P306554; rc_AA955211_r_at; rc_AA955211_i_at; 1393271_at; 6470800; GE1142619; 6137790; 6515146; A_42_P666128; 6742333; 6744223; 5777090; 6277651;  (details...)
Gene Type:	protein-coding
Additional Data
Homologs
Homo sapiens: IHH     See the Human gene in context in:     UCSC     NCBI MapViewer
Mus musculus: Ihh     See the Mouse gene in context in:     UCSC     NCBI MapViewer
Comparative Map Data Species Symbol Map Name Chr. Position Rattus norvegicus Ihh Rat Celera Assembly 9 74074990 - 74081434     RGSC genome assembly v3.4 9 74287115 - 74293332     Cytogenetic 9 q33     genome assembly 3.1 9 74435304 - 74439783 Mus musculus Ihh Mouse genome assembly build 36.1 1 74991892 - 74998225     Cytogenetic 1 1 C3 Homo sapiens IHH Human genome assembly build 36.2 2 219628173 - 219633433     Cytogenetic 2 q33-q35   View comparative maps:      NCBI MapViewer
Genome
View:
Browsers:	Select a browser to viewGene (GBrowse)Gene and SNPs (GBrowse)UCSCVCMAPEnsemblNCBIECRVISTAVISTA+UCSC
Annotation
Molecular Function	Gene Ontology protein binding,  peptidase activity,  receptor binding (details...)
Biological Process	Gene Ontology patterning of blood vessels,  skeletal system development,  negative regulation of signal transduction ...  (details...)
Cellular Component	Gene Ontology extracellular space,  plasma membrane (details...)
Disease	Ontology Hand Deformities, Congenital,  Dwarfism (details...)
Pathway	Ontology altered Hedgehog signaling pathway,  Hedgehog signaling pathway (details...)
External Links
Databases	DATABASE ID SOURCE SMART: HintN IPI SMART: HintC IPI PROSITE: PUR_PYR_PR_TRANSFER IPI PROSITE: INTEIN_N_TER IPI UNIPARC: UPI00000E7E4F IPI UNIPARC: UPI000017EAAE IPI KEGG Report: rno:84399 ENTREZGENE HomoloGene Group ID: 22586 ENTREZGENE Germonline: 620021 Pfam: Hint IPI Pfam: HH_signal IPI KEGG Pathway: 04340 ENTREZGENE InterPro: Intein_splicing_site. IPI InterPro: Peptidase_C46. IPI InterPro: Hedgehog_hint_N. IPI InterPro: HH_signal. IPI InterPro: Peptidase_C46_hint. IPI InterPro: Hedgehog_hint_C. IPI InterPro: Hedgehog/DD-pept_Zn-bd. IPI InterPro: Pr/py_Pribosyl_transf_CS. IPI IPI: IPI00191961 IPI IPI: IPI00366969 IPI Ensembl Protein: ENSRNOP00000024419 IPI Entrez Gene: Ihh ENTREZGENE PIRSF: Peptidase_C46 IPI UniProt: Q9WV29_RAT IPI UniProt: Q9ESH3_RAT IPI Ensembl Genes: ENSRNOG00000018059 IPI Superfamily-SCOP: Hedgehog_sig_N IPI PRINTS: SONICHHOG. IPI
Sequences	Nucleotide: XM_576589 Get FASTA Search GEO Profiles Nucleotide: XM_001060415 Get FASTA Search GEO Profiles Nucleotide: NM_053384 Get FASTA Search GEO Profiles Nucleotide: CH474004 Get FASTA Search GEO Profiles Nucleotide: AF162914 Get FASTA Search GEO Profiles Nucleotide: AF175209 Get FASTA Search GEO Profiles (View all 6 Nucleotide Accessions) Protein: Q9WV29 Get FASTA Protein: NP_445836 Get FASTA Protein: AAG09197 Get FASTA Protein: AAD45372 Get FASTA Protein: XP_576589 Get FASTA Protein: EDL75378 Get FASTA Protein: XP_001060415 Get FASTA Protein: Q9ESH3 Get FASTA (View all 8 Protein Accessions)
Clusters	UniGene: 8711
References
Curated References	10 references in RGD related to Ihh
Other References	8 other references at PubMed related to Ihh
Database Information
RGD ID	620021
History	Date Current Symbol Current Name Previous Symbol Previous name Status Description Reference 22-FEB-08: Ihh Indian hedgehog Ihh Indian hedgehog homolog, (Drosophila) APPROVED Nomenclature updated to reflect human and mouse nomenclature 1299863 20-JAN-05: Ihh Indian hedgehog homolog, (Drosophila) indian hedgehog homolog, (Drosophila) APPROVED Name updated 1299863 07-AUG-02: Ihh indian hedgehog homolog, (Drosophila) PROVISIONAL Symbol and Name status set to provisional 70820