Ptpn23 (protein tyrosine phosphatase, non-receptor type 23) - Rat Genome Database

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Gene: Ptpn23 (protein tyrosine phosphatase, non-receptor type 23) Rattus norvegicus
Analyze
Symbol: Ptpn23
Name: protein tyrosine phosphatase, non-receptor type 23
RGD ID: 619892
Description: Predicted to enable protein kinase binding activity and protein tyrosine phosphatase activity. Predicted to be involved in several processes, including endosomal transport; positive regulation of adherens junction organization; and positive regulation of transport. Predicted to be located in ciliary basal body; early endosome; and nuclear body. Predicted to be active in endosome. Orthologous to human PTPN23 (protein tyrosine phosphatase non-receptor type 23); INTERACTS WITH (+)-schisandrin B; 2,4-dinitrotoluene; 2,6-dinitrotoluene.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: HD-PTP; his domain-containing protein tyrosine phosphatase; protein tyrosine phosphatase TD14; Ptp-Td14; tyrosine-protein phosphatase non-receptor type 23
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr88119,239,213 - 119,261,675 (-)NCBIGRCr8
mRatBN7.28110,360,804 - 110,383,271 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl8110,360,804 - 110,383,271 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx8115,976,297 - 115,998,824 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.08114,175,487 - 114,198,014 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.08112,018,278 - 112,040,806 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.08118,628,777 - 118,651,238 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl8118,628,777 - 118,651,238 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.08117,972,419 - 117,994,931 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.48114,761,478 - 114,768,927 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.18114,780,932 - 114,788,379 (-)NCBI
Celera8109,646,218 - 109,668,775 (-)NCBICelera
Cytogenetic Map8q32NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
ciliary basal body  (IEA,ISO,ISS)
cytoplasm  (ISO,ISS)
early endosome  (IEA,ISO,ISS)
endosome  (IBA,ISO,ISS)
intracellular membrane-bounded organelle  (ISO)
nuclear body  (IEA,ISO)
nucleoplasm  (ISO)
nucleus  (ISO,ISS)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. A novel putative protein-tyrosine phosphatase contains a BRO1-like domain and suppresses Ha-ras-mediated transformation. Cao L, etal., J Biol Chem 1998 Aug 14;273(33):21077-83.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
4. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
5. GOA pipeline RGD automated data pipeline
6. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
7. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:11095967   PMID:19056867   PMID:20393563   PMID:21179510   PMID:21724833   PMID:21757351   PMID:24821423  


Genomics

Comparative Map Data
Ptpn23
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr88119,239,213 - 119,261,675 (-)NCBIGRCr8
mRatBN7.28110,360,804 - 110,383,271 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl8110,360,804 - 110,383,271 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx8115,976,297 - 115,998,824 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.08114,175,487 - 114,198,014 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.08112,018,278 - 112,040,806 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.08118,628,777 - 118,651,238 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl8118,628,777 - 118,651,238 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.08117,972,419 - 117,994,931 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.48114,761,478 - 114,768,927 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.18114,780,932 - 114,788,379 (-)NCBI
Celera8109,646,218 - 109,668,775 (-)NCBICelera
Cytogenetic Map8q32NCBI
PTPN23
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38347,381,021 - 47,413,435 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl347,381,011 - 47,413,435 (+)EnsemblGRCh38hg38GRCh38
GRCh37347,422,511 - 47,454,925 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36347,397,495 - 47,429,935 (+)NCBINCBI36Build 36hg18NCBI36
Build 34347,397,538 - 47,429,935NCBI
Celera347,361,133 - 47,393,570 (+)NCBICelera
Cytogenetic Map3p21.31NCBI
HuRef347,465,405 - 47,497,882 (+)NCBIHuRef
CHM1_1347,372,731 - 47,405,159 (+)NCBICHM1_1
T2T-CHM13v2.0347,397,442 - 47,429,855 (+)NCBIT2T-CHM13v2.0
Ptpn23
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm399110,214,152 - 110,237,278 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl9110,214,150 - 110,237,281 (-)EnsemblGRCm39 Ensembl
GRCm389110,385,084 - 110,408,210 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl9110,385,082 - 110,408,213 (-)EnsemblGRCm38mm10GRCm38
MGSCv379110,287,593 - 110,310,714 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv369110,230,249 - 110,253,380 (-)NCBIMGSCv36mm8
Celera9110,114,048 - 110,137,187 (-)NCBICelera
Cytogenetic Map9F2NCBI
cM Map959.92NCBI
Ptpn23
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542024,869,894 - 24,897,102 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495542024,869,737 - 24,897,196 (-)NCBIChiLan1.0ChiLan1.0
PTPN23
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2247,335,386 - 47,370,508 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1347,340,727 - 47,375,277 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0347,280,706 - 47,314,268 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1348,378,367 - 48,413,739 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl348,379,810 - 48,413,488 (+)Ensemblpanpan1.1panPan2
PTPN23
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12041,485,959 - 41,511,250 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2041,485,195 - 41,587,003 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2041,402,362 - 41,427,545 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02041,968,876 - 41,994,058 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2041,968,884 - 41,994,053 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12041,210,842 - 41,236,027 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02041,611,994 - 41,637,374 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02041,892,621 - 41,917,798 (-)NCBIUU_Cfam_GSD_1.0
Ptpn23
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118201,526,967 - 201,575,339 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365961,094,205 - 1,124,712 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365961,094,285 - 1,124,483 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PTPN23
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1330,190,755 - 30,253,113 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11330,190,659 - 30,252,980 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21333,423,209 - 33,483,647 (+)NCBISscrofa10.2Sscrofa10.2susScr3
PTPN23
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1228,788,927 - 8,821,566 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl228,788,961 - 8,821,316 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666041158,318,824 - 158,351,484 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ptpn23
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473073,975,655 - 74,004,572 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473073,975,490 - 74,004,454 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Ptpn23
95 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:131
Count of miRNA genes:108
Interacting mature miRNAs:113
Transcripts:ENSRNOT00000056145
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1581557Eae16Experimental allergic encephalomyelitis QTL 163.8nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)88462195110921472Rat
631650Stl6Serum triglyceride level QTL 640.0019blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)810378157112202585Rat
1554321Bmd3Bone mineral density QTL 37.90.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)840952565123900184Rat
70197BpQTLcluster8Blood pressure QTL cluster 83.482arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)846531639119088626Rat
70197BpQTLcluster8Blood pressure QTL cluster 83.482arterial blood pressure trait (VT:2000000)pulse pressure (CMO:0000292)846531639119088626Rat
70197BpQTLcluster8Blood pressure QTL cluster 83.482arterial blood pressure trait (VT:2000000)absolute change in systolic blood pressure (CMO:0000607)846531639119088626Rat
70197BpQTLcluster8Blood pressure QTL cluster 83.482arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)846531639119088626Rat
2303171Bp331Blood pressure QTL 3315.570.005arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)861290298119084929Rat
631653Bp125Blood pressure QTL 1253.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)866142385111142385Rat
631210Bw3Body weight QTL35.9mesenteric fat pad mass (VT:0010427)mesenteric fat pad weight to body weight ratio (CMO:0000654)869349194112783834Rat
1300171Bp184Blood pressure QTL 1843.66arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)870513503118219066Rat
8694446Bw170Body weight QTL 17012.070.001retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)871888757116888757Rat
9590292Uminl3Urine mineral level QTL 33.620.001urine mineral amount (VT:0015086)urine electrolyte level (CMO:0000593)871888757116888757Rat
8694200Abfw4Abdominal fat weight QTL 49.070.001visceral adipose mass (VT:0010063)abdominal fat pad weight to body weight ratio (CMO:0000095)871888757116888757Rat
8694392Bw161Body weight QTL 1618.060.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)871888757116888757Rat
1549909Stresp11Stress response QTL 116.830.0019stress-related behavior trait (VT:0010451)number of approaches toward negative stimulus before onset of defensive burying response (CMO:0001960)873473045118473045Rat
2300181Bmd55Bone mineral density QTL 555.70.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)876468691121468691Rat
61437Cia6Collagen induced arthritis QTL 6joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)882460758122812818Rat
2313400Anxrr25Anxiety related response QTL 25aggression-related behavior trait (VT:0015014)tameness/aggressiveness composite score (CMO:0002136)889265192114019816Rat
738011Anxrr9Anxiety related response QTL 96.1exploratory behavior trait (VT:0010471)number of entries into a discrete space in an experimental apparatus (CMO:0000960)893535351123900184Rat
1358893Bp263Blood pressure QTL 2635.01arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)893965141123900184Rat
1358903Bp252Blood pressure QTL 25270.0001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)893965141123900184Rat
738014Anxrr15Anxiety related response QTL 153.60.005locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)895718998123900184Rat
2300182Bmd56Bone mineral density QTL 565.4femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)895718998123900184Rat
724539Cm19Cardiac mass QTL 192.6heart mass (VT:0007028)calculated heart weight (CMO:0000073)8100149864120994388Rat

Markers in Region
UniSTS:236259  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.28110,360,304 - 110,360,447 (+)MAPPERmRatBN7.2
Rnor_6.08118,628,278 - 118,628,420NCBIRnor6.0
Rnor_5.08117,971,920 - 117,972,062UniSTSRnor5.0
RGSC_v3.48114,760,972 - 114,761,114UniSTSRGSC3.4
Celera8109,645,719 - 109,645,861UniSTS
Cytogenetic Map8q32UniSTS
Ptpn23  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.28110,364,962 - 110,365,237 (+)MAPPERmRatBN7.2
Rnor_6.08118,632,936 - 118,633,210NCBIRnor6.0
Rnor_5.08117,976,578 - 117,976,852UniSTSRnor5.0
RGSC_v3.48114,765,630 - 114,765,904UniSTSRGSC3.4
Celera8109,650,378 - 109,650,652UniSTS
Cytogenetic Map8q32UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 26 11 9 4 9 66 28 37 3
Low 17 46 32 15 32 8 11 8 7 4 8 8
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000056145   ⟹   ENSRNOP00000052992
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl8110,360,804 - 110,383,271 (-)Ensembl
Rnor_6.0 Ensembl8118,628,777 - 118,651,238 (-)Ensembl
RefSeq Acc Id: NM_057204   ⟹   NP_476552
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr88119,239,213 - 119,261,675 (-)NCBI
mRatBN7.28110,360,804 - 110,383,271 (-)NCBI
Rnor_6.08118,628,777 - 118,651,238 (-)NCBI
Rnor_5.08117,972,419 - 117,994,931 (-)NCBI
RGSC_v3.48114,761,478 - 114,768,927 (-)RGD
Celera8109,646,218 - 109,668,775 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_476552 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAF13172 (Get FASTA)   NCBI Sequence Viewer  
  EDL77085 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000052992
  ENSRNOP00000052992.1
GenBank Protein O88902 (Get FASTA)   NCBI Sequence Viewer  
Reference Protein Sequences
RefSeq Acc Id: NP_476552   ⟸   NM_057204
- UniProtKB: Q9QZP8 (UniProtKB/Swiss-Prot),   O88902 (UniProtKB/Swiss-Prot),   F1M951 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000052992   ⟸   ENSRNOT00000056145
Protein Domains
BRO1   Tyrosine specific protein phosphatases   Tyrosine-protein phosphatase

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-O88902-F1-model_v2 AlphaFold O88902 1-1499 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13696330
Promoter ID:EPDNEW_R6855
Type:multiple initiation site
Name:Ptpn23_1
Description:protein tyrosine phosphatase, non-receptor type 23
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.08118,651,280 - 118,651,340EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:619892 AgrOrtholog
BioCyc Gene G2FUF-29074 BioCyc
Ensembl Genes ENSRNOG00000020862 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000056145 ENTREZGENE
  ENSRNOT00000056145.3 UniProtKB/TrEMBL
Gene3D-CATH 1.25.40.280 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  3.90.190.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  alix/aip1 in complex with the ypdl late domain UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  alix/aip1 like domains UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro ALIX_V_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  BRO1-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  BRO1_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  BRO1_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Prot-tyrosine_phosphatase-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTPase_domain UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Tyr_Pase_AS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Tyr_Pase_cat UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TYR_PHOSPHATASE_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:117552 UniProtKB/TrEMBL
NCBI Gene 117552 ENTREZGENE
PANTHER PTHR23030 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE 23 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam ALIX_LYPXL_bnd UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  BRO1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Y_phosphatase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Ptpn23 PhenoGen
PRINTS PRTYPHPHTASE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE BRO1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TYR_PHOSPHATASE_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TYR_PHOSPHATASE_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TYR_PHOSPHATASE_PTP UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RatGTEx ENSRNOG00000020862 RatGTEx
SMART BRO1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTPc UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTPc_motif UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF52799 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A6I3E2_RAT UniProtKB/TrEMBL
  F1M951 ENTREZGENE, UniProtKB/TrEMBL
  O88902 ENTREZGENE, UniProtKB/Swiss-Prot
  Q9QZP8 ENTREZGENE
UniProt Secondary Q9QZP8 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2004-02-11 Ptpn23  protein tyrosine phosphatase, non-receptor type 23  Ptp-Td14  protein tyrosine phosphatase TD14  Symbol and Name updated to reflect Human and Mouse nomenclature 625702 APPROVED
2002-08-07 Ptp-Td14  protein tyrosine phosphatase TD14      Symbol and Name status set to provisional 70820 PROVISIONAL

RGD Curation Notes
Note Type Note Reference
gene_domains contains a PTP-like domain, and a proline-rich region with two putative SH3-domain binding sites 633738