Serpind1 (serpin family D member 1) - Rat Genome Database

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Gene: Serpind1 (serpin family D member 1) Rattus norvegicus
Analyze
Symbol: Serpind1
Name: serpin family D member 1
RGD ID: 619854
Description: Predicted to enable serine-type endopeptidase inhibitor activity. Predicted to be involved in blood coagulation. Predicted to be active in extracellular space. Human ortholog(s) of this gene implicated in heparin cofactor II deficiency. Orthologous to human SERPIND1 (serpin family D member 1); PARTICIPATES IN coagulation cascade pathway; complement system pathway; INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: HC-II; heparin cofactor 2; heparin cofactor II; leuserpin 2; leuserpin-2; protease inhibitor leuserpin-2; rls2var1; serine (or cysteine) peptidase inhibitor, clade D, member 1; serine (or cysteine) proteinase inhibitor, clade D, member 1; serpin D1; serpin peptidase inhibitor, clade D (heparin cofactor), member 1
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81197,168,753 - 97,179,830 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1197,168,754 - 97,179,755 (-)EnsemblGRCr8
mRatBN7.21183,664,517 - 83,675,593 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1183,664,518 - 83,675,519 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1192,392,269 - 92,403,338 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01185,053,419 - 85,064,488 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01184,107,025 - 84,118,094 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Dahl_SR_JrHsd1199,032,822 - 99,043,955 (-)NCBIDahl_SR_JrHsd
Lyon_Normotensive1197,229,160 - 97,240,162 (-)NCBILyon_Normotensive
Lyon_Hypertensive1198,153,492 - 98,164,625 (-)NCBILyon_Hypertensive
F344_StmMcwi1196,959,054 - 96,970,056 (-)NCBIF344_StmMcwi
Rnor_6.01187,913,814 - 87,924,880 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1187,913,806 - 87,924,816 (-)Ensemblrn6Rnor6.0
Rnor_5.01190,969,513 - 90,980,577 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41185,666,714 - 85,677,716 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1182,428,108 - 82,439,110 (-)NCBICelera
RGSC_v3.11185,707,310 - 85,718,313 (-)NCBI
Cytogenetic Map11q23NCBI
JBrowse:




Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-schisandrin B  (EXP)
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4-dibromophenyl 2,4,5-tribromophenyl ether  (ISO)
2,4-dinitrotoluene  (EXP)
3,3',4,4'-tetrachlorobiphenyl  (ISO)
4,4'-sulfonyldiphenol  (ISO)
5-fluorouracil  (ISO)
aflatoxin B1  (ISO)
ammonium chloride  (EXP)
benzo[a]pyrene  (EXP,ISO)
bexarotene  (EXP)
bisphenol A  (EXP,ISO)
cadmium atom  (EXP,ISO)
cadmium dichloride  (EXP)
carbon nanotube  (ISO)
CGP 52608  (ISO)
clofibrate  (ISO)
cobalt dichloride  (EXP)
copper atom  (ISO)
copper(0)  (ISO)
copper(II) sulfate  (ISO)
cyclosporin A  (ISO)
dermatan sulfate  (ISO)
dibenz[a,h]anthracene  (EXP)
dibenzo[a,l]pyrene  (EXP)
diethyl maleate  (ISO)
dioxygen  (ISO)
doxorubicin  (ISO)
fenthion  (ISO)
flavonoids  (EXP)
fluoranthene  (EXP)
flutamide  (EXP)
furan  (EXP)
gestodene  (ISO)
glyphosate  (ISO)
hexadecanoic acid  (ISO)
hydroquinone O-beta-D-glucopyranoside  (ISO)
methidathion  (ISO)
methyltestosterone  (ISO)
N-nitrosodiethylamine  (EXP)
nefazodone  (EXP)
nickel atom  (ISO)
nickel dichloride  (EXP)
nimesulide  (EXP)
nitrofen  (EXP)
O-methyleugenol  (ISO)
p-toluidine  (EXP)
paracetamol  (ISO)
perfluorodecanoic acid  (ISO)
perfluorododecanoic acid  (ISO)
perfluorohexanesulfonic acid  (ISO)
perfluorononanoic acid  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
perfluorooctanoic acid  (EXP,ISO)
perfluoroundecanoic acid  (ISO)
pirinixic acid  (ISO)
potassium dichromate  (ISO)
quercetin  (ISO)
resveratrol  (ISO)
sodium arsenite  (ISO)
sodium dichromate  (EXP)
succimer  (ISO)
tauroursodeoxycholic acid  (EXP)
tetrachloromethane  (EXP,ISO)
thioacetamide  (EXP)
trichloroethene  (EXP)
trimellitic anhydride  (ISO)
troglitazone  (ISO)
valproic acid  (ISO)
zinc atom  (ISO)
zinc(0)  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. Molecular and cellular basis for type I heparin cofactor II deficiency (heparin cofactor II Awaji). Kondo S, etal., Blood. 1996 Feb 1;87(3):1006-12.
4. A novel missense mutation in the human plasmin inhibitor (alpha2-antiplasmin) gene associated with a bleeding tendency. Lind B and Thorsen S, Br J Haematol. 1999 Nov;107(2):317-22.
5. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
6. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
7. Plasma levels of heparin cofactor II (HCII) and thrombin-HCII complex in patients with disseminated intravascular coagulation. Noda A, etal., Clin Appl Thromb Hemost. 2002 Jul;8(3):265-71.
8. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
9. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
10. GOA pipeline RGD automated data pipeline
11. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
12. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
13. Comprehensive gene review and curation RGD comprehensive gene curation
14. Inhibitors of fibrinolysis are elevated in atherosclerotic plaque. Robbie LA, etal., Arterioscler Thromb Vasc Biol. 1996 Apr;16(4):539-45.
15. Secondary thrombin-binding site, glycosaminoglycan binding domain and reactive center region of leuserpin-2 are strongly conserved in mammalian species. Westrup D and Ragg H, Biochim Biophys Acta 1994 Jan 18;1217(1):93-6.
Additional References at PubMed
PMID:12477932   PMID:23376485   PMID:23533145   PMID:27068509  


Genomics

Comparative Map Data
Serpind1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81197,168,753 - 97,179,830 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1197,168,754 - 97,179,755 (-)EnsemblGRCr8
mRatBN7.21183,664,517 - 83,675,593 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1183,664,518 - 83,675,519 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1192,392,269 - 92,403,338 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01185,053,419 - 85,064,488 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01184,107,025 - 84,118,094 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Dahl_SR_JrHsd1199,032,822 - 99,043,955 (-)NCBIDahl_SR_JrHsd
Lyon_Normotensive1197,229,160 - 97,240,162 (-)NCBILyon_Normotensive
Lyon_Hypertensive1198,153,492 - 98,164,625 (-)NCBILyon_Hypertensive
F344_StmMcwi1196,959,054 - 96,970,056 (-)NCBIF344_StmMcwi
Rnor_6.01187,913,814 - 87,924,880 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1187,913,806 - 87,924,816 (-)Ensemblrn6Rnor6.0
Rnor_5.01190,969,513 - 90,980,577 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41185,666,714 - 85,677,716 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1182,428,108 - 82,439,110 (-)NCBICelera
RGSC_v3.11185,707,310 - 85,718,313 (-)NCBI
Cytogenetic Map11q23NCBI
SERPIND1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382220,774,113 - 20,787,720 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2220,774,112 - 20,787,721 (+)Ensemblhg38GRCh38
GRCh372221,128,401 - 21,142,008 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362219,458,383 - 19,472,008 (+)NCBIBuild 36Build 36hg18NCBI36
Build 342219,452,940 - 19,466,562NCBI
Celera224,619,743 - 4,633,367 (+)NCBICelera
Cytogenetic Map22q11.21ENTREZGENE
HuRef224,396,258 - 4,409,872 (+)NCBIHuRef
CHM1_12221,128,573 - 21,142,203 (+)NCBICHM1_1
T2T-CHM13v2.02221,182,821 - 21,196,428 (+)NCBIT2T-CHM13v2.0
Serpind1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391617,149,235 - 17,161,438 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1617,149,235 - 17,161,439 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm381617,331,371 - 17,343,574 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1617,331,371 - 17,343,575 (+)Ensemblmm10GRCm38
MGSCv371617,331,464 - 17,343,665 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361617,244,978 - 17,257,135 (+)NCBIMGSCv36mm8
Celera1617,904,289 - 17,916,527 (+)NCBICelera
Cytogenetic Map16A3NCBI
cM Map1610.74NCBI
Serpind1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495544219,525,411 - 19,538,384 (-)Ensembl
ChiLan1.0NW_00495544219,525,411 - 19,537,986 (-)NCBIChiLan1.0ChiLan1.0
SERPIND1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22330,479,547 - 30,494,177 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12233,028,430 - 33,043,063 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0222,997,480 - 3,011,469 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12219,488,733 - 19,502,380 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2219,488,733 - 19,502,380 (+)EnsemblpanPan2panpan1.1
SERPIND1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12630,686,074 - 30,697,437 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2630,686,663 - 30,693,848 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha2630,644,440 - 30,655,802 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.02632,092,332 - 32,104,026 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2632,092,321 - 32,100,437 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12630,140,268 - 30,151,742 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02629,765,126 - 29,776,487 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02630,854,649 - 30,866,010 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Serpind1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118140,443,481 - 140,455,345 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366192,298,893 - 2,310,716 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049366192,298,745 - 2,310,740 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SERPIND1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1450,427,115 - 50,436,468 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.11450,427,121 - 50,436,470 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21453,875,835 - 53,885,198 (+)NCBISscrofa10.2Sscrofa10.2susScr3
SERPIND1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1194,709,896 - 4,724,620 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl194,715,806 - 4,726,111 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_0236660852,274,595 - 2,288,806 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Serpind1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624945915,789 - 932,515 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_004624945919,639 - 932,515 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Serpind1
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v142,600,385 - 2,607,140 (+)NCBIRrattus_CSIRO_v1

miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:238
Count of miRNA genes:168
Interacting mature miRNAs:185
Transcripts:ENSRNOT00000031819
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
10058954Gmadr7Adrenal mass QTL 72.490.0049adrenal gland mass (VT:0010420)both adrenal glands wet weight to body weight ratio (CMO:0002411)117385089499753367Rat
4889859Pur28Proteinuria QTL 2819.50.001urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)115892833699753367Rat
724561Plsm4Polydactyly-luxate syndrome (PLS) morphotypes QTL 40.0003forelimb integrity trait (VT:0010562)front foot phalanges count (CMO:0001947)116796218499753367Rat
7411658Foco27Food consumption QTL 2716.20.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)116985594399753367Rat
631506Bp104Blood pressure QTL 1042.8arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)117330831599753367Rat
1549848Bvd6Brain ventricular dilatation QTL 63.10.0001brain ventricle morphology trait (VT:0000822)hydrocephalus severity score (CMO:0001881)117961851999753367Rat

Markers in Region
D11Wox17  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21183,674,893 - 83,675,061 (+)MAPPERmRatBN7.2
Rnor_6.01187,924,191 - 87,924,358NCBIRnor6.0
Rnor_5.01190,979,890 - 90,980,057UniSTSRnor5.0
RGSC_v3.41185,677,091 - 85,677,258UniSTSRGSC3.4
Celera1182,438,485 - 82,438,652UniSTS
Cytogenetic Map11q23UniSTS
MHAa22f12.seq  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21183,670,701 - 83,670,897 (+)MAPPERmRatBN7.2
Rnor_6.01187,919,999 - 87,920,194NCBIRnor6.0
Rnor_5.01190,975,698 - 90,975,893UniSTSRnor5.0
RGSC_v3.41185,672,899 - 85,673,094UniSTSRGSC3.4
Celera1182,434,293 - 82,434,488UniSTS
Cytogenetic Map11q23UniSTS
RH130116  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21183,664,552 - 83,664,737 (+)MAPPERmRatBN7.2
Rnor_6.01187,913,850 - 87,914,034NCBIRnor6.0
Rnor_5.01190,969,549 - 90,969,733UniSTSRnor5.0
RGSC_v3.41185,666,750 - 85,666,934UniSTSRGSC3.4
Celera1182,428,144 - 82,428,328UniSTS
RH 3.4 Map11722.22UniSTS
Cytogenetic Map11q23UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
13 10 30 88 85 87 59 75 59 4 262 126 3 75 56 56 28 8 8

Sequence


Ensembl Acc Id: ENSRNOT00000031819   ⟹   ENSRNOP00000031829
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1197,168,754 - 97,179,755 (-)Ensembl
mRatBN7.2 Ensembl1183,664,518 - 83,675,519 (-)Ensembl
Rnor_6.0 Ensembl1187,913,819 - 87,924,816 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000084973   ⟹   ENSRNOP00000074639
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1197,168,754 - 97,175,613 (-)Ensembl
mRatBN7.2 Ensembl1183,664,518 - 83,671,652 (-)Ensembl
Rnor_6.0 Ensembl1187,913,806 - 87,921,679 (-)Ensembl
RefSeq Acc Id: NM_024382   ⟹   NP_077358
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81197,168,753 - 97,179,755 (-)NCBI
mRatBN7.21183,664,517 - 83,675,519 (-)NCBI
Dahl_SR_JrHsd1199,032,822 - 99,043,955 (-)NCBI
Lyon_Normotensive1197,229,160 - 97,240,162 (-)NCBI
Lyon_Hypertensive1198,153,492 - 98,164,625 (-)NCBI
F344_StmMcwi1196,959,054 - 96,970,056 (-)NCBI
Rnor_6.01187,913,814 - 87,924,816 (-)NCBI
Rnor_5.01190,969,513 - 90,980,577 (-)NCBI
RGSC_v3.41185,666,714 - 85,677,716 (-)RGD
Celera1182,428,108 - 82,439,110 (-)RGD
Sequence:
RefSeq Acc Id: XM_006248709   ⟹   XP_006248771
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81197,168,753 - 97,179,830 (-)NCBI
mRatBN7.21183,664,517 - 83,675,593 (-)NCBI
Rnor_6.01187,913,814 - 87,924,880 (-)NCBI
Rnor_5.01190,969,513 - 90,980,577 (-)NCBI
Sequence:
RefSeq Acc Id: NP_077358   ⟸   NM_024382
- Peptide Label: precursor
- UniProtKB: Q5BKA6 (UniProtKB/Swiss-Prot),   Q64268 (UniProtKB/Swiss-Prot),   A6JSM3 (UniProtKB/TrEMBL),   A0A0G2K8K3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006248771   ⟸   XM_006248709
- Peptide Label: isoform X1
- UniProtKB: Q5BKA6 (UniProtKB/Swiss-Prot),   Q64268 (UniProtKB/Swiss-Prot),   A6JSM3 (UniProtKB/TrEMBL),   A0A0G2K8K3 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000031829   ⟸   ENSRNOT00000031819
Ensembl Acc Id: ENSRNOP00000074639   ⟸   ENSRNOT00000084973
Protein Domains
SERPIN

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q64268-F1-model_v2 AlphaFold Q64268 1-479 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13698329
Promoter ID:EPDNEW_R8854
Type:initiation region
Name:Serpind1_1
Description:serpin family D member 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01187,924,806 - 87,924,866EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:619854 AgrOrtholog
BioCyc Gene G2FUF-20585 BioCyc
Ensembl Genes ENSRNOG00000001865 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000031819 ENTREZGENE
  ENSRNOT00000031819.6 UniProtKB/Swiss-Prot
  ENSRNOT00000084973 ENTREZGENE
Gene3D-CATH 2.30.39.10 UniProtKB/Swiss-Prot
  3.30.497.10 UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:7372906 IMAGE-MGC_LOAD
InterPro HCII UniProtKB/Swiss-Prot
  Serpin_CS UniProtKB/Swiss-Prot
  Serpin_dom UniProtKB/Swiss-Prot
  Serpin_fam UniProtKB/Swiss-Prot
  Serpin_sf UniProtKB/Swiss-Prot
  Serpin_sf_1 UniProtKB/Swiss-Prot
  Serpin_sf_2 UniProtKB/Swiss-Prot
KEGG Report rno:79224 UniProtKB/Swiss-Prot
MGC_CLONE MGC:108674 IMAGE-MGC_LOAD
NCBI Gene 79224 ENTREZGENE
PANTHER HEPARIN COFACTOR 2 UniProtKB/Swiss-Prot
  PTHR11461 UniProtKB/Swiss-Prot
Pfam Serpin UniProtKB/Swiss-Prot
PhenoGen Serpind1 PhenoGen
PRINTS LEUSERPINII UniProtKB/Swiss-Prot
PROSITE SERPIN UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000001865 RatGTEx
SMART SERPIN UniProtKB/Swiss-Prot
Superfamily-SCOP SSF56574 UniProtKB/Swiss-Prot
UniProt A0A0G2K8K3 ENTREZGENE, UniProtKB/TrEMBL
  A6JSM3 ENTREZGENE, UniProtKB/TrEMBL
  HEP2_RAT UniProtKB/Swiss-Prot
  Q5BKA6 ENTREZGENE
  Q64268 ENTREZGENE
UniProt Secondary Q5BKA6 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-04-13 Serpind1  serpin family D member 1  Serpind1  serpin peptidase inhibitor, clade D (heparin cofactor), member 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2011-01-19 Serpind1  serpin peptidase inhibitor, clade D (heparin cofactor), member 1  Serpind1  serine (or cysteine) peptidase inhibitor, clade D, member 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-03-30 Serpind1  serine (or cysteine) peptidase inhibitor, clade D, member 1    serine (or cysteine) proteinase inhibitor, clade D, member 1  Name updated 1299863 APPROVED
2004-12-14 Serpind1  serine (or cysteine) proteinase inhibitor, clade D, member 1    leuserpin-2  Name updated 1299863 APPROVED
2002-08-07 Serpind1  leuserpin-2      Symbol and Name status set to provisional 70820 PROVISIONAL