Rag1 (recombination activating 1) - Rat Genome Database

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Gene: Rag1 (recombination activating 1) Rattus norvegicus
Analyze
Symbol: Rag1
Name: recombination activating 1
RGD ID: 619790
Description: Predicted to enable several functions, including histone binding activity; protein homodimerization activity; and zinc ion binding activity. Predicted to contribute to double-stranded DNA endonuclease activity. Involved in regulation of behavioral fear response and visual learning. Predicted to be located in nucleoplasm. Predicted to be part of DNA recombinase complex and endodeoxyribonuclease complex. Predicted to be active in nucleus. Used to study hypertension and severe combined immunodeficiency. Human ortholog(s) of this gene implicated in Omenn syndrome; combined cellular and humoral immune defects with granulomas; severe combined immunodeficiency; and severe combined immunodeficiency, autosomal recessive, T cell-negative, B cell-negative, Nk cell-positive. Orthologous to human RAG1 (recombination activating 1); PARTICIPATES IN primary immunodeficiency pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; ammonium chloride; amphetamine.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: LOC295954; recombination activating gene 1; recombination activation protein 1; recombination-activating protein 1; V(D)J recombination-activating protein 1
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Allele / Splice: Rag1em1Mcwi ; Rag1em2Mcwi ; Rag1em1Ztm ; Rag1em1Ang ; Rag1em1Sage ; Rag1em6Mcwi
Genetic Models: LEW-Rag1em1Ztm ; SS-Rag1em2Mcwi ; SS-Rag1em1Mcwi ; SD-Fahem3McwiIl2rgem2McwiRag1em6Mcwi ; SD-Rag1em1Ang ; SD-Rag1em1Sage ; F344-Rag1em1Sage
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83108,372,087 - 108,383,184 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl3108,371,978 - 108,383,261 (-)EnsemblGRCr8
mRatBN7.2387,917,061 - 87,928,158 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl387,917,004 - 87,928,291 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx391,407,934 - 91,419,028 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.03100,006,959 - 100,018,053 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0397,839,202 - 97,850,299 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0391,206,394 - 91,217,491 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl391,206,394 - 91,217,491 (-)Ensemblrn6Rnor6.0
Rnor_5.0397,866,048 - 97,877,145 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4386,780,782 - 86,791,878 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera387,023,254 - 87,034,352 (-)NCBICelera
RGSC_v3.1386,683,155 - 86,683,666 (-)NCBI
Cytogenetic Map3q31NCBI
JBrowse:




Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
Phenotype Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Contribution of Rag1 to spatial memory ability in rats. Fang M, etal., Behav Brain Res. 2013 Jan 1;236(1):200-9. doi: 10.1016/j.bbr.2012.09.002. Epub 2012 Sep 8.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. GENETIC MUTATION OF RECOMBINATION ACTIVATING GENE 1 IN DAHL SALT-SENSITIVE RATS ATTENUATES HYPERTENSION AND RENAL DAMAGE. Mattson DL, etal., Am J Physiol Regul Integr Comp Physiol. 2013 Jan 30.
4. Generation of Rag1-knockout immunodeficient rats and mice using engineered meganucleases. Menoret S, etal., FASEB J. 2012 Nov 12.
5. Generation of immunodeficient rats with Rag1 and Il2rg gene deletions and human tissue grafting models. Ménoret S, etal., Transplantation. 2018 Apr 24. doi: 10.1097/TP.0000000000002251.
6. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
7. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
8. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
9. Evidence for the extrathymic origin of intestinal TCRgammadelta(+) T cells in normal rats and for an impairment of this differentiation pathway in BB rats. Ramanathan S, etal., J Immunol 2002 Mar 1;168(5):2182-7.
10. GOA pipeline RGD automated data pipeline
11. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
12. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
13. Comprehensive gene review and curation RGD comprehensive gene curation
14. RAG mutations in human B cell-negative SCID. Schwarz K, etal., Science. 1996 Oct 4;274(5284):97-9.
15. Partial V(D)J recombination activity leads to Omenn syndrome. Villa A, etal., Cell. 1998 May 29;93(5):885-96.
16. Zinc-finger nuclease mediated disruption of Rag1 in the LEW/Ztm rat. Zschemisch NH, etal., BMC Immunol. 2012 Nov 8;13:60. doi: 10.1186/1471-2172-13-60.
Additional References at PubMed
PMID:1547488   PMID:2360047   PMID:8284210   PMID:9215624   PMID:9228952   PMID:10601033   PMID:11214319   PMID:11976687   PMID:12629039   PMID:14670978   PMID:14671314   PMID:15371245  
PMID:15522792   PMID:15728238   PMID:16929832   PMID:18684012   PMID:19396172   PMID:19448632   PMID:20122409   PMID:21149691   PMID:22801499   PMID:29537860  


Genomics

Comparative Map Data
Rag1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83108,372,087 - 108,383,184 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl3108,371,978 - 108,383,261 (-)EnsemblGRCr8
mRatBN7.2387,917,061 - 87,928,158 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl387,917,004 - 87,928,291 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx391,407,934 - 91,419,028 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.03100,006,959 - 100,018,053 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0397,839,202 - 97,850,299 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0391,206,394 - 91,217,491 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl391,206,394 - 91,217,491 (-)Ensemblrn6Rnor6.0
Rnor_5.0397,866,048 - 97,877,145 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4386,780,782 - 86,791,878 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera387,023,254 - 87,034,352 (-)NCBICelera
RGSC_v3.1386,683,155 - 86,683,666 (-)NCBI
Cytogenetic Map3q31NCBI
RAG1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381136,510,353 - 36,579,762 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1136,510,372 - 36,593,156 (+)Ensemblhg38GRCh38
GRCh371136,531,903 - 36,601,312 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361136,546,139 - 36,557,851 (+)NCBIBuild 36Build 36hg18NCBI36
Build 341136,546,138 - 36,557,871NCBI
Celera1136,741,994 - 36,753,743 (+)NCBICelera
Cytogenetic Map11p12NCBI
HuRef1136,292,349 - 36,304,098 (+)NCBIHuRef
CHM1_11136,588,249 - 36,599,998 (+)NCBICHM1_1
T2T-CHM13v2.01136,653,524 - 36,722,938 (+)NCBIT2T-CHM13v2.0
Rag1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm392101,468,597 - 101,479,877 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl2101,468,627 - 101,479,846 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm382101,638,252 - 101,649,532 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2101,638,282 - 101,649,501 (-)Ensemblmm10GRCm38
MGSCv372101,478,409 - 101,489,689 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv362101,439,121 - 101,450,340 (-)NCBIMGSCv36mm8
Celera2102,863,243 - 102,874,521 (-)NCBICelera
Cytogenetic Map2E2NCBI
cM Map253.88NCBI
Rag1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554229,891,878 - 9,919,504 (-)Ensembl
ChiLan1.0NW_0049554229,891,878 - 9,928,569 (-)NCBIChiLan1.0ChiLan1.0
RAG1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2938,787,605 - 38,794,076 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11138,792,269 - 38,798,740 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01136,483,697 - 36,546,242 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11136,356,483 - 36,418,891 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1136,412,420 - 36,422,904 (+)EnsemblpanPan2panpan1.1
RAG1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11831,628,231 - 31,639,980 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1831,630,737 - 31,641,660 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha1831,238,815 - 31,241,946 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.01832,241,825 - 32,244,956 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1832,241,825 - 32,244,956 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11831,811,828 - 31,814,959 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01831,396,201 - 31,399,332 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01832,033,403 - 32,036,534 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Rag1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494728,691,865 - 28,695,927 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365331,817,135 - 1,827,393 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049365331,817,135 - 1,827,393 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
RAG1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl224,561,156 - 24,573,851 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1224,565,447 - 24,573,853 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2226,730,528 - 26,733,659 (-)NCBISscrofa10.2Sscrofa10.2susScr3
RAG1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1128,667,996 - 28,701,002 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_023666038125,803,873 - 125,811,767 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Rag1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462476710,694,867 - 10,698,001 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462476710,694,867 - 10,698,041 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Rag1
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v1579,469,849 - 79,481,046 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Rag1
76 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:1140
Count of miRNA genes:355
Interacting mature miRNAs:503
Transcripts:ENSRNOT00000006115
Prediction methods:Microtar, Miranda, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1300178Hrtrt4Heart rate QTL 43.74heart pumping trait (VT:2000009)heart rate (CMO:0000002)351490129111359995Rat
1358293Bw38Body weight QTL 3860.0000031body mass (VT:0001259)body weight (CMO:0000012)374364268119364268Rat
61377Edpm3Estrogen-dependent pituitary mass QTL 37.050.038pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)373592611110333156Rat
2301414Kidm37Kidney mass QTL 370.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)396509147141509147Rat
1582238Bw68Body weight QTL 683.20.0064body mass (VT:0001259)body weight (CMO:0000012)373592512136118980Rat
1582239Epfw1Epididymal fat weight QTL 14.50.0006epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)373592512136118980Rat
70216Cm14Cardiac mass QTL 142.1heart mass (VT:0007028)heart wet weight (CMO:0000069)351581665184004958Rat
2292591Esta4Estrogen-induced thymic atrophy QTL 4thymus mass (VT:0004954)thymus wet weight (CMO:0000855)367641776167835660Rat
1358362Srcrt2Stress Responsive Cort QTL 22.78blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)358601291153936591Rat
737818Hcar12Hepatocarcinoma resistance QTL 122.6liver integrity trait (VT:0010547)volume of individual liver tumorous lesion (CMO:0001078)349872657138829559Rat
1582218Bw74Body weight QTL 743.90.0021body mass (VT:0001259)body weight (CMO:0000012)373592512136118980Rat
1582221Kidm30Kidney mass QTL 303.50.0008kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)385062224136118980Rat
1582210Bw71Body weight QTL 713.30.0012body mass (VT:0001259)body weight (CMO:0000012)385062224136118980Rat
7387306Bw124Body weight QTL 1243.20.0003body mass (VT:0001259)body weight (CMO:0000012)3104545086149545086Rat
1300111Rf12Renal function QTL 123.78renal blood flow trait (VT:2000006)absolute change in renal blood flow rate (CMO:0001168)381425008141509147Rat
724523Tsu1Thymus enlargement suppressive QTL 13.84thymus mass (VT:0004954)thymus weight to body weight ratio (CMO:0000612)370845569136091483Rat
1600376Arunc5Aerobic running capacity QTL 50.21exercise endurance trait (VT:0002332)longest distance run on treadmill (CMO:0001406)393829559138829559Rat
2302273Gluco35Glucose level QTL 355.30.001blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)3101255536134750886Rat
8662816Vetf4Vascular elastic tissue fragility QTL 44renal artery integrity trait (VT:0010642)number of ruptures of the internal elastic lamina of the renal arteries (CMO:0002563)379649560177741895Rat
1581503Cm58Cardiac mass QTL 582.70.05heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)396509147141509147Rat
2292613Ept16Estrogen-induced pituitary tumorigenesis QTL 168.3pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)367641995130815812Rat
631841Niddm39Non-insulin dependent diabetes mellitus QTL 393.36blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)370311536115311536Rat
631200Cm25Cardiac mass QTL 254.80.0001heart left ventricle mass (VT:0007031)heart left ventricle wet weight (CMO:0000071)381541464126563126Rat
12879848Bw181Body weght QTL 1810.015body mass (VT:0001259)body weight (CMO:0000012)390755164141509147Rat
1358905Hrtrt17Heart rate QTL 175.90.000014heart pumping trait (VT:2000009)heart rate (CMO:0000002)336721849110333156Rat
1354597Kidm13Kidney mass QTL 132.9kidney mass (VT:0002707)right kidney wet weight (CMO:0000082)342158111124558371Rat
1358885Bp251Blood pressure QTL 2513.8arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)31141509147Rat
1581546Pur13Proteinuria QTL 132.930.0335urine total protein amount (VT:0000032)urine protein excretion rate (CMO:0000759)398651826167012663Rat
1354604Bw36Body weight QTL 362.9body mass (VT:0001259)body weight (CMO:0000012)342158111124558371Rat
1358888Bp264Blood pressure QTL 2644.43arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)35675975141509147Rat
1358186Ept2Estrogen-induced pituitary tumorigenesis QTL 28.3pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)367641995130815812Rat

Markers in Region
GDB:624547  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr83108,375,915 - 108,376,489 (+)Marker Load Pipeline
mRatBN7.2387,920,889 - 87,921,462 (+)MAPPERmRatBN7.2
Rnor_6.0391,210,223 - 91,210,795NCBIRnor6.0
Rnor_5.0397,869,877 - 97,870,449UniSTSRnor5.0
RGSC_v3.4386,784,610 - 86,785,182UniSTSRGSC3.4
Celera387,027,084 - 87,027,656UniSTS
Cytogenetic Map3q31UniSTS


Genetic Models
This gene Rag1 is modified in the following models/strains:
LEW-Rag1em1Ztm     SS-Rag1em2Mcwi     SS-Rag1em1Mcwi     SD-Fahem3McwiIl2rgem2McwiRag1em6Mcwi     SD-Rag1em1Ang     SD-Rag1em1Sage     F344-Rag1em1Sage    


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
7 9 38 62 75 77 50 58 50 217 117 11 45 35 54 27 5 5

Sequence


Ensembl Acc Id: ENSRNOT00000006115   ⟹   ENSRNOP00000006115
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl3108,371,978 - 108,383,261 (-)Ensembl
mRatBN7.2 Ensembl387,917,004 - 87,928,291 (-)Ensembl
Rnor_6.0 Ensembl391,206,394 - 91,217,491 (-)Ensembl
RefSeq Acc Id: NM_053468   ⟹   NP_445920
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83108,372,087 - 108,383,184 (-)NCBI
mRatBN7.2387,917,061 - 87,928,158 (-)NCBI
Rnor_6.0391,206,394 - 91,217,491 (-)NCBI
Rnor_5.0397,866,048 - 97,877,145 (-)NCBI
RGSC_v3.4386,780,782 - 86,791,878 (-)RGD
Celera387,023,254 - 87,034,352 (-)RGD
Sequence:
RefSeq Acc Id: NP_445920   ⟸   NM_053468
- UniProtKB: G3V6K9 (UniProtKB/TrEMBL),   A6HNM3 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000006115   ⟸   ENSRNOT00000006115
Protein Domains
NBD   RAG1 importin-binding   RAG1-type   RING-type

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-G3V6K9-F1-model_v2 AlphaFold G3V6K9 1-1040 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13692243
Promoter ID:EPDNEW_R2766
Type:multiple initiation site
Name:Rag1_1
Description:recombination activating 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0391,217,521 - 91,217,581EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:619790 AgrOrtholog
BioCyc Gene G2FUF-48611 BioCyc
Ensembl Genes ENSRNOG00000004630 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000006115 ENTREZGENE
  ENSRNOT00000006115.7 UniProtKB/TrEMBL
Gene3D-CATH 3.30.40.10 UniProtKB/TrEMBL
  6.10.140.510 UniProtKB/TrEMBL
  Classic Zinc Finger UniProtKB/TrEMBL
InterPro RAG1 UniProtKB/TrEMBL
  RAG1_imp-bd UniProtKB/TrEMBL
  RAG_nonamer-bd_dom UniProtKB/TrEMBL
  Znf_C2H2_sf UniProtKB/TrEMBL
  Znf_C3HC4_RING-type UniProtKB/TrEMBL
  Znf_RING UniProtKB/TrEMBL
  Znf_RING/FYVE/PHD UniProtKB/TrEMBL
  Znf_RING_CS UniProtKB/TrEMBL
  Znf_VDJ_recomb-activ_1 UniProtKB/TrEMBL
KEGG Report rno:84600 UniProtKB/TrEMBL
NCBI Gene 84600 ENTREZGENE
PANTHER PTHR11539 UniProtKB/TrEMBL
  V(D)J RECOMBINATION-ACTIVATING PROTEIN 1 UniProtKB/TrEMBL
Pfam RAG1 UniProtKB/TrEMBL
  RAG1_imp_bd UniProtKB/TrEMBL
  zf-C3HC4 UniProtKB/TrEMBL
  zf-RAG1 UniProtKB/TrEMBL
PhenoGen Rag1 PhenoGen
PROSITE NBD UniProtKB/TrEMBL
  ZF_RAG1 UniProtKB/TrEMBL
  ZF_RING_1 UniProtKB/TrEMBL
  ZF_RING_2 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000004630 RatGTEx
SMART RING UniProtKB/TrEMBL
Superfamily-SCOP RING/U-box UniProtKB/TrEMBL
  SSF57667 UniProtKB/TrEMBL
UniProt A0A858CAG1_RAT UniProtKB/TrEMBL
  A6HNM3 ENTREZGENE, UniProtKB/TrEMBL
  G3V6K9 ENTREZGENE, UniProtKB/TrEMBL
  O70607_RAT UniProtKB/TrEMBL
  Q68AY0_RAT UniProtKB/TrEMBL
  Q6WDI9_RAT UniProtKB/TrEMBL
  Q99NN7_RAT UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2006-04-27 Rag1  recombination activating gene 1  Rag1_predicted  recombination activating gene 1 (predicted)  Data merged from RGD:1308224 737654 APPROVED
2005-01-20 Rag1  recombination activating gene 1    recombination activation protein 1  Name updated 1299863 APPROVED
2005-01-12 Rag1_predicted  recombination activating gene 1 (predicted)      Symbol and Name status set to approved 70820 APPROVED
2002-08-07 Rag1  recombination activation protein 1      Symbol and Name status set to provisional 70820 PROVISIONAL