Rps8 (ribosomal protein S8) - Rat Genome Database

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Gene: Rps8 (ribosomal protein S8) Rattus norvegicus
Analyze
Symbol: Rps8
Name: ribosomal protein S8
RGD ID: 61910
Description: Predicted to be a structural constituent of ribosome. Predicted to be involved in maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA). Part of cytosolic small ribosomal subunit. Orthologous to human RPS8 (ribosomal protein S8); PARTICIPATES IN ribosome biogenesis pathway; translation pathway; INTERACTS WITH 1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane; 1-naphthyl isothiocyanate; 17alpha-ethynylestradiol.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: 40S ribosomal protein S8; small ribosomal subunit protein eS8
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Related Pseudogenes: Rps8-ps1   Rps8-ps18  
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr85135,866,941 - 135,869,511 (-)NCBIGRCr8
mRatBN7.25130,630,362 - 130,632,932 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl5130,629,716 - 130,633,268 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx5133,254,801 - 133,257,371 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.05135,009,404 - 135,011,974 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.05135,031,836 - 135,034,406 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.05136,020,941 - 136,023,511 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5136,020,941 - 136,023,511 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.05139,813,893 - 139,816,579 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45137,466,705 - 137,469,275 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.15137,471,930 - 137,474,501 (-)NCBI
Celera5129,151,937 - 129,154,507 (-)NCBICelera
Cytogenetic Map5q36NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(1->4)-beta-D-glucan  (ISO)
1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane  (EXP)
1,2-dimethylhydrazine  (ISO)
1-naphthyl isothiocyanate  (EXP)
17alpha-ethynylestradiol  (EXP,ISO)
17beta-hydroxy-17-methylestra-4,9,11-trien-3-one  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,6-dinitrotoluene  (EXP)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
4,4'-diaminodiphenylmethane  (ISO)
4,4'-sulfonyldiphenol  (EXP,ISO)
5-methoxy-2-\{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl\}-1H-benzimidazole  (EXP)
6-propyl-2-thiouracil  (EXP)
amiodarone  (EXP)
ammonium chloride  (EXP)
amphotericin B  (ISO)
arsenite(3-)  (ISO)
benzbromarone  (EXP)
benzo[a]pyrene  (ISO)
bisphenol A  (EXP,ISO)
Bisphenol B  (ISO)
bisphenol F  (EXP,ISO)
Brodifacoum  (EXP)
bromobenzene  (EXP)
caffeine  (ISO)
carbon nanotube  (ISO)
chloropicrin  (ISO)
chlorpyrifos  (ISO)
chromium(6+)  (ISO)
clobetasol  (ISO)
clofibrate  (EXP)
dexamethasone  (ISO)
dihydroartemisinin  (ISO)
doxorubicin  (ISO)
enzyme inhibitor  (ISO)
ethanol  (EXP)
fenthion  (ISO)
flutamide  (EXP)
FR900359  (ISO)
furan  (ISO)
gentamycin  (EXP)
indometacin  (EXP,ISO)
ivermectin  (ISO)
L-ethionine  (EXP)
lead(0)  (ISO)
methidathion  (ISO)
miconazole  (ISO)
nitric oxide  (ISO)
omeprazole  (EXP)
ozone  (ISO)
paracetamol  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
pirinixic acid  (EXP,ISO)
Propiverine  (EXP)
rimonabant  (ISO)
S-butyl-DL-homocysteine (S,R)-sulfoximine  (ISO)
SB 431542  (ISO)
sodium arsenite  (EXP,ISO)
Soman  (EXP)
tetrachloromethane  (EXP)
thapsigargin  (EXP)
thioacetamide  (EXP)
trichloroethene  (EXP)
tungsten  (ISO)
zearalenone  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Structures of the human and Drosophila 80S ribosome. Anger AM, etal., Nature. 2013 May 2;497(7447):80-5. doi: 10.1038/nature12104.
2. The primary structure of rat ribosomal protein S8. Chan YL, etal., Nucleic Acids Res 1987 Nov 25;15(22):9451-9.
3. The isolation of eukaryotic ribosomal proteins. The purification and characterization of the 40 S ribosomal subunit proteins S2, S3, S4, S5, S6, S7, S8, S9, S13, S23/S24, S27, and S28. Collatz E, etal., J Biol Chem. 1976 Aug 10;251(15):4666-72.
4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
5. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
6. Functional dichotomy of ribosomal proteins during the synthesis of mammalian 40S ribosomal subunits. O'Donohue MF, etal., J Cell Biol. 2010 Sep 6;190(5):853-66. doi: 10.1083/jcb.201005117.
7. Semiquantitative proteomic analysis of rat forebrain postsynaptic density fractions by mass spectrometry. Peng J, etal., J Biol Chem. 2004 May 14;279(20):21003-11. doi: 10.1074/jbc.M400103200. Epub 2004 Mar 12.
8. GOA pipeline RGD automated data pipeline
9. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
10. Comprehensive gene review and curation RGD comprehensive gene curation
11. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
12. Tentative Sequence Identification Numbers Tentative Sequence Data IDs. TIGR Gene Index, Rat Data
Additional References at PubMed
PMID:398910   PMID:8706699   PMID:15489334   PMID:15883184   PMID:16854843   PMID:17289661   PMID:19946888   PMID:20458337   PMID:21423176   PMID:21630459   PMID:21700703   PMID:22658674  
PMID:22681889   PMID:22871113   PMID:23376485   PMID:24625528   PMID:26316108   PMID:30053369   PMID:35352799  


Genomics

Comparative Map Data
Rps8
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr85135,866,941 - 135,869,511 (-)NCBIGRCr8
mRatBN7.25130,630,362 - 130,632,932 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl5130,629,716 - 130,633,268 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx5133,254,801 - 133,257,371 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.05135,009,404 - 135,011,974 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.05135,031,836 - 135,034,406 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.05136,020,941 - 136,023,511 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5136,020,941 - 136,023,511 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.05139,813,893 - 139,816,579 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45137,466,705 - 137,469,275 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.15137,471,930 - 137,474,501 (-)NCBI
Celera5129,151,937 - 129,154,507 (-)NCBICelera
Cytogenetic Map5q36NCBI
RPS8
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38144,775,540 - 44,778,779 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl144,775,251 - 44,778,779 (+)EnsemblGRCh38hg38GRCh38
GRCh37145,241,212 - 45,244,451 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36145,013,833 - 45,016,999 (+)NCBINCBI36Build 36hg18NCBI36
Build 34144,910,338 - 44,913,505NCBI
Celera143,524,133 - 43,527,299 (+)NCBICelera
Cytogenetic Map1p34.1NCBI
HuRef143,354,301 - 43,357,468 (+)NCBIHuRef
CHM1_1145,357,155 - 45,360,321 (+)NCBICHM1_1
T2T-CHM13v2.0144,646,529 - 44,649,769 (+)NCBIT2T-CHM13v2.0
Rps8
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm394117,011,033 - 117,013,329 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl4117,011,024 - 117,013,440 (-)EnsemblGRCm39 Ensembl
GRCm384117,153,836 - 117,156,132 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl4117,153,827 - 117,156,243 (-)EnsemblGRCm38mm10GRCm38
MGSCv374116,826,441 - 116,828,737 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv364116,651,768 - 116,654,064 (-)NCBIMGSCv36mm8
Celera4115,892,449 - 115,894,875 (-)NCBICelera
Cytogenetic Map4D1NCBI
cM Map453.41NCBI
Rps8
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495546413,443,631 - 13,445,389 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495546413,443,580 - 13,445,391 (-)NCBIChiLan1.0ChiLan1.0
RPS8
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21182,029,610 - 182,032,869 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11181,171,032 - 181,174,275 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0144,078,633 - 44,081,891 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1145,444,879 - 45,448,166 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl145,444,879 - 45,448,166 (+)Ensemblpanpan1.1panPan2
RPS8
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11515,542,569 - 15,545,285 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1515,542,580 - 15,545,163 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1515,662,878 - 15,665,489 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01515,698,190 - 15,700,801 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1515,697,116 - 15,700,775 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11515,495,395 - 15,498,006 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01515,562,696 - 15,565,307 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01515,635,756 - 15,638,369 (-)NCBIUU_Cfam_GSD_1.0
Rps8
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505860,181,401 - 60,184,044 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647426,006,217 - 26,009,505 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647426,006,226 - 26,008,824 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
RPS8
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl6166,549,949 - 166,553,230 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.16166,550,574 - 166,553,289 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.26154,026,501 - 154,029,235 (+)NCBISscrofa10.2Sscrofa10.2susScr3
RPS8
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12088,011,614 - 88,014,769 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2088,010,616 - 88,015,477 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603328,921,775 - 28,924,988 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Rps8
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624906669,496 - 672,635 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624906669,466 - 671,933 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Rps8
18 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:40
Count of miRNA genes:37
Interacting mature miRNAs:38
Transcripts:ENSRNOT00000025796
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1549845Scl44Serum cholesterol level QTL 446blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)540128307148607290Rat
8552960Pigfal15Plasma insulin-like growth factor 1 level QTL 15blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)5111416838156416838Rat
1300122Wbc1White blood cell count QTL 12.75leukocyte quantity (VT:0000217)total white blood cell count (CMO:0000365)5125392826139989768Rat
61452Ciaa5CIA Autoantibody QTL 53.5blood autoantibody amount (VT:0003725)calculated serum anti-rat type 2 collagen autoantibody titer (CMO:0001281)594858972143070159Rat
70156Niddm30Non-insulin dependent diabetes mellitus QTL 303.98blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)5129132447151006154Rat
7411582Foco3Food consumption QTL 37.50.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)587468046132468046Rat
1302790Scl20Serum cholesterol level QTL 206.40.0001blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)582394392166664054Rat
1598861Cm64Cardiac mass QTL 642.9heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)5127798274166875058Rat
1578766Tcas11Tongue tumor susceptibility QTL 114.12tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)546711509161317411Rat
1549838Bss4Bone structure and strength QTL 49.2femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)5106906205151906205Rat
2317753Glom24Glomerulus QTL 243.1kidney glomerulus integrity trait (VT:0010546)kidney sclerotic glomeruli count to total glomeruli count ratio (CMO:0001269)597570330136479578Rat
7411564Bw135Body weight QTL 1350.001body mass (VT:0001259)body weight gain (CMO:0000420)587468046132468046Rat
8694169Bw148Body weight QTL 14850.001body mass (VT:0001259)body weight gain (CMO:0000420)5128506074166875058Rat
8657050Bw146Body weight QTL 14619.840.001body mass (VT:0001259)body weight gain (CMO:0000420)5108938288153938288Rat
1641912Alcrsp18Alcohol response QTL 18response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)535189153141643988Rat
2317056Wbc3White blood cell count QTL 32.510.01leukocyte quantity (VT:0000217)white blood cell count (CMO:0000027)5105999803150999803Rat
724525Bp147Blood pressure QTL 1474.30.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)5126424772166875058Rat
2293642Bss37Bone structure and strength QTL 374.640.0001femur strength trait (VT:0010010)femur ultimate force (CMO:0001675)5120740824151018848Rat
1578673Bmd13Bone mineral density QTL 134.9femur mineral mass (VT:0010011)trabecular volumetric bone mineral density (CMO:0001729)5103689353148689353Rat
70189Mcs5Mammary carcinoma susceptibility QTL 510.51mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)555805606132207589Rat
7207488Bss110Bone structure and strength QTL 18.4femur strength trait (VT:0010010)femur stiffness (CMO:0001674)5106906205151906205Rat
8694441Bw169Body weight QTL 16917.610.001retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)5111416838156416838Rat
7207491Bss112Bone structure and strength QTL 1127femur morphology trait (VT:0000559)femur midshaft cortical cross-sectional area (CMO:0001663)5106906205151906205Rat
2290448Scl54Serum cholesterol level QTL 542.93blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)531663789131345958Rat
8694198Abfw3Abdominal fat weight QTL 316.130.001visceral adipose mass (VT:0010063)abdominal fat pad weight to body weight ratio (CMO:0000095)5111416838156416838Rat
1298089Scl14Serum cholesterol level QTL 145.80.0004blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)5108845856153845856Rat
1331796Thshl2Thyroid stimulating hormone level QTL 22.3blood thyroid-stimulating hormone amount (VT:0005119)serum thyroid stimulating hormone level (CMO:0001248)597059760147465714Rat
10053720Scort26Serum corticosterone level QTL 262.060.0147blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)5124965598166875058Rat
70212Niddm25Non-insulin dependent diabetes mellitus QTL 253.54blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)51131345958Rat
7365049Bp359Blood pressure QTL 359arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)5128071929134724733Rat
8552908Pigfal4Plasma insulin-like growth factor 1 level QTL 46.6blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)5128506074166875058Rat
1331803Rf32Renal function QTL 322.798kidney blood vessel physiology trait (VT:0100012)absolute change in renal vascular resistance (CMO:0001900)5129132428143070159Rat
61393Bp7Blood pressure QTL 74.50.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)560293434161481680Rat
7207486Bss109Bone structure and strength QTL 109femur strength trait (VT:0010010)femur total energy absorbed before break (CMO:0001677)5106906205151906205Rat
7207481Bss106Bone structure and strength QTL 1067.9femur strength trait (VT:0010010)femur ultimate force (CMO:0001675)5106906205151906205Rat
1641920Colcs1Colorectal carcinoma susceptibility QTL 12.990.0055intestine integrity trait (VT:0010554)benign colorectal tumor surface area measurement (CMO:0001799)5121846814166846814Rat
1581505Rf54Renal function QTL 54kidney physiology trait (VT:0002136)kidney 20-HETE level (CMO:0001854)5128033842133011550Rat
1581510Cm54Cardiac mass QTL 543.40.05heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)5120740824143608494Rat
1576312Emca8Estrogen-induced mammary cancer QTL 84.1mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)550328551141643988Rat
7411601Foco12Food consumption QTL 1219.70.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)587468046132468046Rat
1576314Eutr1Estrogen induced uterine response QTL 1uterus integrity trait (VT:0010575)pyometritis severity score (CMO:0002009)52138965166875058Rat
634349Bp139Blood pressure QTL 1390.001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)5128924607166875058Rat
7394710Emca12Estrogen-induced mammary cancer QTL 12mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)5124160767133749643Rat
1598847Cm62Cardiac mass QTL 623.4heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)5108845856153845856Rat
738018Anxrr4Anxiety related response QTL 45.1exploratory behavior trait (VT:0010471)percentage of entries into a discrete space in an experimental apparatus (CMO:0000961)5130130159166875058Rat
631527Tls1T-lymphoma susceptibility QTL 100.001thymus integrity trait (VT:0010555)post-insult time to onset of T-cell lymphoma (CMO:0001907)590450144135450144Rat
8694389Bw160Body weight QTL 1606.170.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)5111416838156416838Rat
61426Scl2Serum cholesterol level QTL 27.30.001blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)559793399143070159Rat
1354598Srn6Serum renin concentration QTL 63.8blood renin amount (VT:0003349)plasma renin activity level (CMO:0000116)569540295151018848Rat
1598819Bp292Blood pressure QTL 2924.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)5127798274166875058Rat
6903316Bw113Body weight QTL 11320.0103body mass (VT:0001259)body weight (CMO:0000012)587765973132765973Rat
1358187Emca1Estrogen-induced mammary cancer QTL 14.4mammary gland integrity trait (VT:0010552)post-insult time to mammary tumor formation (CMO:0000345)599216724148607142Rat


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31

Sequence


Ensembl Acc Id: ENSRNOT00000081747   ⟹   ENSRNOP00000074753
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl5130,630,362 - 130,633,268 (-)Ensembl
Rnor_6.0 Ensembl5136,020,941 - 136,023,511 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000109040   ⟹   ENSRNOP00000091201
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl5130,629,716 - 130,632,775 (-)Ensembl
RefSeq Acc Id: NM_031706   ⟹   NP_113894
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85135,866,941 - 135,869,511 (-)NCBI
mRatBN7.25130,630,362 - 130,632,932 (-)NCBI
Rnor_6.05136,020,941 - 136,023,511 (-)NCBI
Rnor_5.05139,813,893 - 139,816,579 (-)NCBI
RGSC_v3.45137,466,705 - 137,469,275 (-)RGD
Celera5129,151,937 - 129,154,507 (-)RGD
Sequence:
RefSeq Acc Id: XM_063288367   ⟹   XP_063144437
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85135,868,435 - 135,869,499 (-)NCBI
RefSeq Acc Id: NP_113894   ⟸   NM_031706
- UniProtKB: P62243 (UniProtKB/Swiss-Prot),   B2RYR8 (UniProtKB/TrEMBL),   A0A8L2R9H0 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000074753   ⟸   ENSRNOT00000081747
Ensembl Acc Id: ENSRNOP00000091201   ⟸   ENSRNOT00000109040
RefSeq Acc Id: XP_063144437   ⟸   XM_063288367
- Peptide Label: isoform X1

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P62243-F1-model_v2 AlphaFold P62243 1-208 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13693949
Promoter ID:EPDNEW_R4474
Type:initiation region
Name:Rps8_1
Description:ribosomal protein S8
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.05136,023,511 - 136,023,571EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:61910 AgrOrtholog
BioCyc Gene G2FUF-40215 BioCyc
Ensembl Genes ENSRNOG00000054626 Ensembl, UniProtKB/TrEMBL
  ENSRNOG00055012609 UniProtKB/Swiss-Prot
  ENSRNOG00060030056 UniProtKB/Swiss-Prot
  ENSRNOG00065016980 UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000081747.2 UniProtKB/TrEMBL
  ENSRNOT00000109040.1 UniProtKB/TrEMBL
  ENSRNOT00055021504 UniProtKB/Swiss-Prot
  ENSRNOT00060052212 UniProtKB/Swiss-Prot
  ENSRNOT00065028324 UniProtKB/Swiss-Prot
Gene3D-CATH 1.10.168.20 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  3.10.290.70 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:6920981 IMAGE-MGC_LOAD
  IMAGE:7302521 IMAGE-MGC_LOAD
InterPro Ribosomal_protein_S8e_euk UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ribosomal_S8e UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ribosomal_S8e/biogenesis_NSA2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ribosomal_S8e_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:65136 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGC_CLONE MGC:105393 IMAGE-MGC_LOAD
  MGC:188809 IMAGE-MGC_LOAD
NCBI Gene 65136 ENTREZGENE
PANTHER 40S RIBOSOMAL PROTEIN S8 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR10394 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Ribosomal_S8e UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Rps8 PhenoGen
PROSITE RIBOSOMAL_S8E UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RatGTEx ENSRNOG00000054626 RatGTEx
  ENSRNOG00055012609 RatGTEx
  ENSRNOG00060030056 RatGTEx
  ENSRNOG00065016980 RatGTEx
TIGR TC204188
UniProt A0A8I6AEU6_RAT UniProtKB/TrEMBL
  A0A8L2R9H0 ENTREZGENE, UniProtKB/TrEMBL
  B2RYR8 ENTREZGENE, UniProtKB/TrEMBL
  P62243 ENTREZGENE, UniProtKB/Swiss-Prot
UniProt Secondary P09058 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2002-06-10 Rps8  ribosomal protein S8      Name updated 70584 APPROVED

RGD Curation Notes
Note Type Note Reference
gene_protein 207 amino acids and has a molecular weight of 23,928 61744