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Gene: Strn (striatin) Rattus norvegicus

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Symbol:

Strn

Name:

striatin

RGD ID:

3782

Description:

Enables calmodulin binding activity and protein domain specific binding activity. Involved in dendrite development; locomotory behavior; and regulation of modification of postsynaptic structure. Located in dendritic spine; neuronal cell body; and postsynaptic membrane. Part of protein-containing complex. Is active in glutamatergic synapse and postsynaptic density. Orthologous to human STRN (striatin); INTERACTS WITH 17alpha-ethynylestradiol; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

striatin, calmodulin binding protein

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	STRN (striatin)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, Treefam
Mus musculus (house mouse):	Strn (striatin, calmodulin binding protein)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Strn (striatin)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	STRN (striatin)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	STRN (striatin)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Strn (striatin)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	STRN (striatin)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	STRN (striatin)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Strn (striatin)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus rattus (black rat):	Strn (striatin)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Homo sapiens (human):	STRN (striatin)	Alliance	DIOPT (HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Strn (striatin, calmodulin binding protein)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	strn (striatin, calmodulin binding protein)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Saccharomyces cerevisiae (baker's yeast):	FAR8	Alliance	DIOPT (Ensembl Compara\|OrthoFinder\|PANTHER)
Drosophila melanogaster (fruit fly):	Cka	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)
Caenorhabditis elegans (roundworm):	cash-1	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	strn	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	6	22,087,419 - 22,174,284 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	6	22,087,497 - 22,193,048 (+)	Ensembl				GRCr8
mRatBN7.2	6	16,335,265 - 16,422,159 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	6	16,335,358 - 16,417,083 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	6	16,644,013 - 16,725,908 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	6	16,966,222 - 17,048,119 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	6	16,447,405 - 16,530,225 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	6	1,232,729 - 1,319,603 (-)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	6	1,237,758 - 1,319,541 (-)	Ensembl			rn6	Rnor6.0
Rnor_5.0	6	1,223,200 - 1,310,035 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	6	1,428,548 - 1,510,817 (-)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	6	15,984,038 - 16,065,613 (+)	NCBI		Celera
RGSC_v3.1	8	38,404,106 - 38,404,723 (+)	NCBI
Cytogenetic Map	6	q12	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Brain Injuries (IEP)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(-)-epigallocatechin 3-gallate (ISO)

1,2-dimethylhydrazine (ISO)

17alpha-ethynylestradiol (EXP)

17beta-estradiol (EXP)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2-methoxyethanol (EXP)

4-hydroxyphenyl retinamide (ISO)

6-propyl-2-thiouracil (EXP)

aflatoxin B1 (ISO)

all-trans-retinoic acid (ISO)

ammonium chloride (EXP)

antirheumatic drug (ISO)

aristolochic acid A (ISO)

arsenite(3-) (ISO)

atrazine (ISO)

bisphenol A (EXP,ISO)

caffeine (ISO)

CGP 52608 (ISO)

coumarin (ISO)

cyclosporin A (ISO)

DDE (ISO)

Dibutyl phosphate (ISO)

dorsomorphin (ISO)

doxorubicin (ISO)

entinostat (ISO)

ethanol (ISO)

FR900359 (ISO)

gentamycin (EXP)

GSK-J4 (ISO)

hydrogen peroxide (ISO)

ivermectin (ISO)

manganese(II) chloride (ISO)

methoxychlor (EXP)

methyl methanesulfonate (ISO)

methylmercury chloride (ISO)

mono(2-ethylhexyl) phthalate (ISO)

N-nitrosodiethylamine (EXP)

okadaic acid (ISO)

oxaliplatin (EXP)

paracetamol (ISO)

phenethyl caffeate (EXP)

phenylmercury acetate (ISO)

pirinixic acid (ISO)

potassium chromate (ISO)

resveratrol (ISO)

SB 431542 (ISO)

sodium arsenite (ISO)

tetrachloromethane (EXP)

thiram (ISO)

titanium dioxide (ISO)

topotecan (EXP)

trichostatin A (ISO)

triphenyl phosphate (ISO)

tungsten (ISO)

urethane (ISO)

valproic acid (ISO)

vincaleukoblastine (ISO)

vitamin E (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

dendrite development (IMP)

locomotory behavior (IMP)

negative regulation of cell population proliferation (IEA,ISO)

regulation of modification of postsynaptic structure (IDA,IMP)

regulation of signal transduction (IBA)

Wnt signaling pathway (IBA,IEA,ISO)

Cellular Component

bicellular tight junction (IEA,ISO)

cell junction (IEA)

cytoplasm (IEA)

dendrite (IBA)

dendritic spine (IDA,IEA)

FAR/SIN/STRIPAK complex (IBA,IEA,ISO)

glutamatergic synapse (IDA)

membrane (IEA)

neuronal cell body (IBA,IDA)

postsynapse (IBA,IDA)

postsynaptic density (IDA)

postsynaptic membrane (IDA)

protein-containing complex (IDA,IEA)

Molecular Function

armadillo repeat domain binding (IEA,ISO)

calcium-dependent protein binding (NAS)

calmodulin binding (IDA,IEA)

nuclear estrogen receptor binding (IEA,ISO)

protein binding (IPI,ISO)

protein domain specific binding (IEA,IPI)

protein phosphatase 2A binding (IEA,ISO)

protein-containing complex binding (IEA,IPI,ISO)

protein-macromolecule adaptor activity (IBA)

References

References - curated

#	Reference Title	Reference Citation
1.	Molecular cloning and characterization of phocein, a protein found from the Golgi complex to dendritic spines.	Baillat G, etal., Mol Biol Cell 2001 Mar;12(3):663-73.
2.	Down-regulation of striatin, a neuronal calmodulin-binding protein, impairs rat locomotor activity.	Bartoli M, etal., J Neurobiol. 1999 Aug;40(2):234-43.
3.	Expression and distribution of phocein and members of the striatin family in neurones of rat peripheral ganglia.	Blondeau C, etal., Histochem Cell Biol. 2003 Feb;119(2):131-8. Epub 2003 Feb 7.
4.	A novel calmodulin-binding protein, belonging to the WD-repeat family, is localized in dendrites of a subset of CNS neurons.	Castets F, etal., J Cell Biol 1996 Aug;134(4):1051-62.
5.	Striatin, a calmodulin-dependent scaffolding protein, directly binds caveolin-1.	Gaillard S, etal., FEBS Lett. 2001 Nov 9;508(1):49-52.
6.	Targeting of proteins of the striatin family to dendritic spines: role of the coiled-coil domain.	Gaillard S, etal., Traffic. 2006 Jan;7(1):74-84.
7.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
8.	Rat ISS GO annotations from GOA human gene data--August 2006	GOA data from the GO Consortium
9.	Relationships between striatin-containing neurons and cortical or thalamic afferent fibres in the rat striatum. An ultrastructural study by dual labelling.	Kachidian P, etal., Neuroscience. 1998 Jul;85(1):111-22. doi: 10.1016/s0306-4522(97)00593-9.
10.	Striatin-1 is a B subunit of protein phosphatase PP2A that regulates dendritic arborization and spine development in striatal neurons.	Li D, etal., J Biol Chem. 2018 Jul 13;293(28):11179-11194. doi: 10.1074/jbc.RA117.001519. Epub 2018 May 25.
11.	Comparing calpain- and caspase-3-mediated degradation patterns in traumatic brain injury by differential proteome analysis.	Liu MC, etal., Biochem J. 2006 Mar 15;394(Pt 3):715-25.
12.	Electronic Transfer of LocusLink and RefSeq Data	NCBI rat LocusLink and RefSeq merged data July 26, 2002
13.	GOA pipeline	RGD automated data pipeline
14.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
15.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
16.	Tentative Sequence Identification Numbers	Tentative Sequence Data IDs. TIGR Gene Index, Rat Data

Additional References at PubMed

PMID:15569929	PMID:18502210	PMID:18782753	PMID:28825318	PMID:30053369	PMID:31565882

Genomics

Comparative Map Data

Strn
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	6	22,087,419 - 22,174,284 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	6	22,087,497 - 22,193,048 (+)	Ensembl				GRCr8
mRatBN7.2	6	16,335,265 - 16,422,159 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	6	16,335,358 - 16,417,083 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	6	16,644,013 - 16,725,908 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	6	16,966,222 - 17,048,119 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	6	16,447,405 - 16,530,225 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	6	1,232,729 - 1,319,603 (-)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	6	1,237,758 - 1,319,541 (-)	Ensembl			rn6	Rnor6.0
Rnor_5.0	6	1,223,200 - 1,310,035 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	6	1,428,548 - 1,510,817 (-)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	6	15,984,038 - 16,065,613 (+)	NCBI		Celera
RGSC_v3.1	8	38,404,106 - 38,404,723 (+)	NCBI
Cytogenetic Map	6	q12	NCBI

STRN
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	2	36,837,698 - 36,966,536 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	2	36,837,698 - 36,966,625 (-)	Ensembl			hg38	GRCh38
GRCh37	2	37,064,841 - 37,193,679 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	2	36,928,976 - 37,047,119 (-)	NCBI	Build 36	Build 36	hg18	NCBI36
Build 34	2	36,987,122 - 37,105,266	NCBI
Celera	2	36,916,520 - 37,034,632 (-)	NCBI		Celera
Cytogenetic Map	2	p22.2	NCBI
HuRef	2	36,805,145 - 36,933,870 (-)	NCBI		HuRef
CHM1_1	2	36,994,082 - 37,122,881 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	2	36,844,882 - 36,973,674 (-)	NCBI		T2T-CHM13v2.0

Strn
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	17	78,957,327 - 79,043,990 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	17	78,957,342 - 79,044,625 (-)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	17	78,649,898 - 78,737,322 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	17	78,649,913 - 78,737,196 (-)	Ensembl			mm10	GRCm38
MGSCv37	17	79,053,304 - 79,135,900 (-)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	17	78,559,022 - 78,641,618 (-)	NCBI		MGSCv36	mm8
Celera	17	82,961,171 - 83,054,539 (-)	NCBI		Celera
Cytogenetic Map	17	E3	NCBI
cM Map	17	49.54	NCBI

Strn
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955441	4,682,200 - 4,781,275 (-)	Ensembl
ChiLan1.0	NW_004955441	4,682,200 - 4,781,236 (-)	NCBI	ChiLan1.0	ChiLan1.0

STRN
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	12	89,514,075 - 89,636,703 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	2A	89,518,060 - 89,640,679 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	2A	36,870,487 - 36,993,103 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	2A	37,632,899 - 37,713,550 (-)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	2A	37,637,543 - 37,713,550 (-)	Ensembl			panPan2	panpan1.1

STRN
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	17	29,264,693 - 29,364,273 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	17	29,272,833 - 29,332,869 (-)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	17	29,083,296 - 29,179,262 (-)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	17	29,918,572 - 30,014,742 (-)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	17	29,918,576 - 30,013,760 (-)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	17	29,146,408 - 29,242,571 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	17	29,208,066 - 29,304,578 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	17	29,427,442 - 29,523,408 (-)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Strn
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024406292	42,606,057 - 42,714,700 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936663	1,271,548 - 1,377,655 (+)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936663	1,271,549 - 1,377,609 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

STRN
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	3	103,249,884 - 103,351,902 (+)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	3	103,249,826 - 103,364,750 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	3	109,829,466 - 109,935,208 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

STRN
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	14	70,437,593 - 70,563,631 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	14	70,437,570 - 70,558,013 (+)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM
Vero_WHO_p1.0	NW_023666045	41,395,122 - 41,516,122 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Strn
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624738	18,476,522 - 18,585,160 (-)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
HetGla 1.0	NW_004624738	18,474,603 - 18,585,109 (-)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Strn
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	7	14,494,995 - 14,575,713 (+)	NCBI		Rrattus_CSIRO_v1

Variants

Variants in Strn
252 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	357
Count of miRNA genes:	216
Interacting mature miRNAs:	243
Transcripts:	ENSRNOT00000006527
Prediction methods:	Microtar, Miranda, Rnahybrid
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
8552962	Pigfal16	Plasma insulin-like growth factor 1 level QTL 16	9.4		blood insulin-like growth factor amount (VT:0010479)	plasma insulin-like growth factor 1 level (CMO:0001299)	6	1975879	46975879	Rat
7411603	Foco13	Food consumption QTL 13	5.5	0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	6	1975879	46975879	Rat
1598843	Cm63	Cardiac mass QTL 63	2.6		heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	6	1	44788383	Rat
7411542	Bw127	Body weight QTL 127	5.5	0.001	body mass (VT:0001259)	body weight gain (CMO:0000420)	6	1975879	46975879	Rat
8693699	Alc37	Alcohol consumption QTL 37	2.6	0.224	drinking behavior trait (VT:0001422)	calculated ethanol drink intake rate (CMO:0001615)	6	13717169	27053860	Rat
2293706	Bmd20	Bone mineral density QTL 20	4.3	0.0002	femur mineral mass (VT:0010011)	total volumetric bone mineral density (CMO:0001728)	6	1	25740059	Rat
2292616	Ept15	Estrogen-induced pituitary tumorigenesis QTL 15	4.4		pituitary gland mass (VT:0010496)	pituitary gland wet weight (CMO:0000853)	6	1	44788383	Rat
9589048	Scfw3	Subcutaneous fat weight QTL 3	4.57	0.001	subcutaneous adipose mass (VT:1000472)	abdominal subcutaneous fat pad weight (CMO:0002069)	6	1975879	46975879	Rat
10401812	Kidm54	Kidney mass QTL 54			kidney mass (VT:0002707)	both kidneys wet weight (CMO:0000085)	6	20097635	65097635	Rat
1576309	Emca7	Estrogen-induced mammary cancer QTL 7	4		mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	6	20859430	113082285	Rat
2301964	Bp323	Blood pressure QTL 323	4.3		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	6	1	86868070	Rat
2293709	Bss23	Bone structure and strength QTL 23	5.18	0.0001	femur morphology trait (VT:0000559)	femur cross-sectional area (CMO:0001661)	6	3239989	48239989	Rat
2293650	Bss31	Bone structure and strength QTL 31	5.05	0.0001	femur strength trait (VT:0010010)	femur midshaft polar moment of inertia (CMO:0001669)	6	3239989	48239989	Rat
1300128	Rf16	Renal function QTL 16	3.89		renal blood flow trait (VT:2000006)	absolute change in renal blood flow rate (CMO:0001168)	6	1	40163351	Rat
70199	Coreg1	Compensatory renal growth QTL 1	11.8		kidney mass (VT:0002707)	compensatory renal growth score (CMO:0001894)	6	14599473	63457687	Rat
10401800	Kidm49	Kidney mass QTL 49			kidney mass (VT:0002707)	both kidneys wet weight (CMO:0000085)	6	20097635	65097635	Rat
1300164	Rf15	Renal function QTL 15	3.12		renal blood flow trait (VT:2000006)	absolute change in renal blood flow rate (CMO:0001168)	6	3239989	48239989	Rat
2301972	Bp325	Blood pressure QTL 325	4.8		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	6	16089372	61967788	Rat
1358190	Ept1	Estrogen-induced pituitary tumorigenesis QTL 1	4.4		pituitary gland mass (VT:0010496)	pituitary gland wet weight (CMO:0000853)	6	1	44788383	Rat
2293656	Bss28	Bone structure and strength QTL 28	6.79	0.0001	femur morphology trait (VT:0000559)	femur midshaft cortical cross-sectional area (CMO:0001663)	6	3239989	48239989	Rat
9589129	Insul24	Insulin level QTL 24	19.06	0.001	blood insulin amount (VT:0001560)	plasma insulin level (CMO:0000342)	6	1975879	46975879	Rat
8693690	Alc35	Alcohol consumption QTL 35	2.2	0.606	drinking behavior trait (VT:0001422)	calculated ethanol drink intake rate (CMO:0001615)	6	13717169	27053860	Rat

Markers in Region

D6Rat44

Rat Assembly	Chr	Position (strand)	Source	JBrowse
GRCr8	6	22,088,648 - 22,088,825 (+)	Marker Load Pipeline
mRatBN7.2	6	16,336,509 - 16,336,688 (-)	MAPPER	mRatBN7.2
Rnor_6.0	6	1,318,186 - 1,318,362	NCBI	Rnor6.0
Rnor_5.0	6	1,308,655 - 1,308,831	UniSTS	Rnor5.0
RGSC_v3.4	6	1,509,500 - 1,509,677	RGD	RGSC3.4
RGSC_v3.4	6	1,509,501 - 1,509,677	UniSTS	RGSC3.4
Celera	6	15,985,178 - 15,985,354	UniSTS
RGSC_v3.1	6	1,509,501 - 1,509,677	RGD
RH 3.4 Map	6	30.5	UniSTS
RH 3.4 Map	6	30.5	RGD
RH 2.0 Map	6	128.7	RGD
Cytogenetic Map	6	q11	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
16	12	67	165	91	90	59	92	59	6	356	192	11	144	81	92	31	17	17

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_019148	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006239622	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039111825	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	FQ212484	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000006	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000006527 ⟹ ENSRNOP00000006527

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	6	22,087,497 - 22,169,217 (+)	Ensembl
mRatBN7.2 Ensembl	6	16,335,358 - 16,417,083 (+)	Ensembl
Rnor_6.0 Ensembl	6	1,237,758 - 1,319,541 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000118929 ⟹ ENSRNOP00000093598

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	6	22,087,497 - 22,169,217 (+)	Ensembl
mRatBN7.2 Ensembl	6	16,335,358 - 16,417,083 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000172485 ⟹ ENSRNOP00000112827

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	6	22,087,497 - 22,193,048 (+)	Ensembl

RefSeq Acc Id:

NM_019148 ⟹ NP_062021

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	6	22,087,509 - 22,169,206 (+)	NCBI
mRatBN7.2	6	16,335,370 - 16,417,072 (+)	NCBI
Rnor_6.0	6	1,237,809 - 1,319,502 (-)	NCBI
Rnor_5.0	6	1,223,200 - 1,310,035 (-)	NCBI
RGSC_v3.4	6	1,428,548 - 1,510,817 (-)	RGD
Celera	6	15,984,038 - 16,065,613 (+)	RGD

Sequence:

show sequence

TGCTGGGCGCCTAGGCAGAGCTACCCACGGGGTTTCGTGCGGCCGCCATGGACGAGCAGGCGGG
GCCCGGCGTCTTCTTCAGCAACAACCATCCGGGAGCTGGCGGTGCTAAGGGGCTCGGGCCTCTG
GCGGAGGCTGCAGCGGCGGGAGACGGAGCGGCTGCGGCGGGGGCGGCCCGAGCTCAGTACAGCC
TCCCGGGGATCTTGCACTTCCTGCAGCACGAATGGGCCCGCTTCGAGGTGGAGAGAGCCCAGTG
GGAGGTGGAGCGGGCGGAGTTGCAGGCTCAGATTGCTTTCCTTCAGGGGGAGAGGAAAGGCCAA
GAAAACTTGAAGAAAGATCTTGTGAGGAGGATCAAAATGTTGGAATATGCTCTGAAGCAGGAAA
GAGCCAAATACCACAAGTTGAAATATGGGACAGAACTGAATCAGGGAGACATGAAGCCTCCAAG
CTATGATTCTGATGAAGGCAATGAAACGGAGGTGCAGCCACAGCAGAACAGCCAGTTCATGTGG
AAGCAAGGCCGGCAGCTCCTCAGACAGTATCTCCAGGAGGTCGGCTACACAGATACTATTCTAG
ATGTGAAGTCCAAGCGTGTGCGGGCATTGTTGGGCTTTTCAAGTGATGTCACTGACAGGGAGGA
TGACAAAAACCAGGACTCGGTGATAAATGGCACAGAGGCTGAAGTTAAAGAGACAGCAATGATT
GGAAAATCTGAGTTAACGGATTCTGCCTCCGTGCTGGACAATTTCAAATTCCTTGAAAATGCAG
CTGCAGATTTCAGTGATGAAGACGAGGATGAGGACATTGATGGAAGAGAGAAAAGTGTCATTGA
TACTTCAACCATTGTTAGGAAAAAACCATTACCTGATACCAGTGAAGATCGAGACACAAAAGAA
GCTCTGAAGGAGTTTGACTTCCTTGTCGCCTCAGAGGAAGGAGACAACGAGTCCAGAAGTGCAG
GCGACGGAACGGACTGGGAAAAGGAAGATCAGTGTCTGACGCCGGAGCGCTGGAATGTGGACCA
GGGAGTGATCACCAGACTGAAGGAGCAGTACAAAAAGGAGAGGAAGGGGAAGAAAGGGGTGAAG
AGGCCCAATAGGTCAAAACTACAAGATATGCTTGCTAATTTGAGAGACGTTGATGAACTTCCCT
CCTTGCAGCCATCTGTTGGCTCCCCTTCCAGACCCAGCAGCTCCAGGCTTCCTGAGCAGGACAT
CAGTAGGGCAGATGAAGTGGAAGCATTGACGTTCCCGCCTTCTTCAGGGAAGTCATTTATCATG
GGAGCAGATGAAGCCCTTGAAAGCGAGCTGGGGCTTGGAGAATTAGCAGGCCTTACAGTGGCCA
ATGAAGCAGACTCATTAGCTTATGATATAGCGAATAACAAAGACGCCTTGAGGAAGACGTGGAA
CCCTAAGTTTACATTAAGGAGTCACTTTGATGGCATCCGAGCCCTTGCTTTCCACCCCATCGAG
CCTGTGTTAATAACCGCGTCAGAGGACCACACGCTGAAAATGTGGAATCTGCAGAAAACAGCCC
CAGCTAAAAAGAGTACTTCTTTAGATGTGGAGCCTATCTACACCTTCAGGGCTCACAAAGGTCC
GGTGCTGTGTGTGGTCATGAGTAGCAATGGTGAGCAGTGCTACAGCGGCGGCACTGATGGCCTC
ATCCAGAGCTGGAGCACCACCAATCCCAACGTCGACCCCTACGATTCTTATGATCCTTCGGTTC
TAAGAGGCCCTCTGTTGGGCCACACGGATGCGGTGTGGGGGCTGGCCTACAGCGCGGCCCACCA
GCGCTTGTTGTCCTGTTCAGCAGACGGCACTCTTCGTCTATGGACCACCACTGAGGTTGCTCCA
GCGCTGACTGTATTTAATGATAACCAAGAACTGGGAATCCCTGCTTCTGTGGATCTGGTGAGCA
GTGACCCGAGCCATATGGTAGCATCGTTCAGCAAGGGATATACAAGCATCTTCAACATGGAAAC
ACAGCAGCGAATTCTCACGTTAGAATCCAATGTCGATTCAACGGCCAGTTCTTCCTGCCAAATA
AACAGAGTCATCAGTCACCCCACCCTCCCGATCAGCATCACTGCTCACGAGGACAGGCACATCA
AGTTCTACGATAACAACACAGGCAAACTGATCCACTCGATGGTGGCCCACCTGGAAGCCGTTAC
AAGTTTGGCGGTTGATCCCAACGGCCTGTACCTGATGTCTGGCAGTCATGACTGTTCAATACGC
TTGTGGAATTTAGAAAGTAAGACGTGTATCCAGGAGTTCACAGCTCATCGGAAAAAGTTTGAAG
AGTCGATCCATGATGTAGCATTCCACCCTTCTAAATGCTATATAGCCAGCGCTGGAGCCGACGC
CCTGGCTAAGGTCTTTGTATGATGGGGTACTTCAGCTTCACCCTGCAGCTCTTACAAGTCAACC
GCACACAGGAAACGGAAGACCAGGGCGGGAGCCAGCTCGCCCTGCCCTTTTGTTTGGCTGAGGG
AGCACAGAGACCTCTGTTAAAGTACAGTTTTGCAGTTCCTATACAGTTTTCTAAAATTAAGGTT
TGTTCAGGTTGCTGCAAGCTCAGCTGAACCTGTGAGCCCGAAACTTTCAGATCCCCCCAAAGAG
GCACTTTTATTTCTGAGGTTGTTCTCACTCGCTAGGCGGGCCCGAGCGTTCGTTCTCCCTTTTG
AGTAAGCAGGGCATGCTGTAATGGATAATTAGAGGTGAATGCCGGGAATGAGTAGAATGGAAAT
TTAACTATCCTTCCACCCCGAGACATCTGCTACCACACTAGGTAGTCAGCTCTGCGGCTGTGTG
TGCTCTACTAACCCCACTGTGTAGAAGGAGACAGTGTGTGTCAGTGTTCACATGAGGTCCTCCC
GCTGCTGTCCTCTCAGACCGTTCTCATGAAGCACAGGGAAGAGTGTTCCTTCCACCTGTAGGAG
GAAGAGATGCAATAATATGATTAATTATATGATATTCAGAA

hide sequence

RefSeq Acc Id:

XM_006239622 ⟹ XP_006239684

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	6	22,087,419 - 22,174,284 (+)	NCBI
mRatBN7.2	6	16,335,265 - 16,422,159 (+)	NCBI
Rnor_6.0	6	1,232,729 - 1,319,603 (-)	NCBI
Rnor_5.0	6	1,223,200 - 1,310,035 (-)	NCBI

Sequence:

show sequence

GCCCGGCCCCCGCGCCCGGGCGGCTGCTCCCTGCTGACTGGGGTGTGGGCGGGGAGCGGCGGAG
GGAGGAGGCAGAGCTGGCCGCCGCAGTTTGCCGCCGCTGCTGGGCGCCTAGGCAGAGCTCCCCG
GGGTTCGTGCGGCCGCCATGGACGAGCAGGCGGGGCCCGGCGTCTTCTTCAGCAACAACCATCC
GGGAGCTGGCGGTGCTAAGGGGCTCGGGCCTCTGGCGGAGGCTGCAGCGGCGGGAGACGGAGCG
GCTGCGGCGGGGGCGGCCCGAGCTCAGTACAGCCTCCCGGGGATCTTGCACTTCCTGCAGCACG
AATGGGCCCGCTTCGAGGTGGAGAGAGCCCAGTGGGAGGTGGAGCGGGCGGAGTTGCAGGCTCA
GATTGCTTTCCTTCAGGGGGAGAGGAAAGGCCAAGAAAACTTGAAGAAAGATCTTGTGAGGAGG
ATCAAAATGTTGGAATATGCTCTGAAGCAGGAAAGAGCCAAATACCACAAGTTGAAATATGGGA
CAGAACTGAATCAGGGAGACATGAAGCCTCCAAGCTATGATTCTGATGAAGGCAATGAAACGGA
GGTGCAGCCACAGCAGAACAGCCAGTTCATGTGGAAGCAAGGCCGGCAGCTCCTCAGACAGTAT
CTCCAGGAGGTCGGCTACACAGATACTATTCTAGATGTGAAGTCCAAGCGTGTGCGGGCATTGT
TGGGCTTTTCAAGTGATGTCACTGACAGGGAGGATGACAAAAACCAGGACTCGGTGATAAATGG
CACAGAGGCTGAAGTTAAAGAGACAGCAATGATTGGAAAATCTGAGTTAACGGATTCTGCCTCC
GTGCTGGACAATTTCAAATTCCTTGAAAATGCAGCTGCAGATTTCAGTGATGAAGACGAGGATG
AGGACATTGATGGAAGAGAGAAAAGTGTCATTGATACTTCAACCATTGTTAGGAAAAAACCATT
ACCTGATACCAGTGAAGATCGAGACACAAAAGAAGCTCTGAAGGAGTTTGACTTCCTTGTCGCC
TCAGAGGAAGGAGACAACGAGTCCAGAAGTGCAGGCGACGGAACGGACTGGGAAAAGGAAGATC
AGTGTCTGACGCCGGAGGCCTGGAATGTGGACCAGGGAGTGATCACCAGACTGAAGGAGCAGTA
CAAAAAGGAGAGGAAGGGGAAGAAAGGGGTGAAGAGAAAAACTACCGAAGATCTGTTTCAGCCT
CTATCCTATATAAAACAGTCAAAACAGGGATGTGGGAGAATGAAGAAGCAAAGCCCAGGGCCCA
ATAGGTCAAAACTACAAGATATGCTTGCTAATTTGAGAGACGTTGATGAACTTCCCTCCTTGCA
GCCATCTGTTGGCTCCCCTTCCAGACCCAGCAGCTCCAGGCTTCCTGAGCAGGACATCAGTAGG
GCAGATGAAGTGGAAGCATTGACGTTCCCGCCTTCTTCAGGGAAGTCATTTATCATGGGAGCAG
ATGAAGCCCTTGAAAGCGAGCTGGGGCTTGGAGAATTAGCAGGCCTTACAGTGGCCAATGAAGC
AGACTCATTAGCTTATGATATAGCGAATAACAAAGACGCCTTGAGGAAGACGTGGAACCCTAAG
TTTACATTAAGGAGTCACTTTGATGGCATCCGAGCCCTTGCTTTCCACCCCATCGAGCCTGTGT
TAATAACCGCGTCAGAGGACCACACGCTGAAAATGTGGAATCTGCAGAAAACAGCCCCAGCTAA
AAAGAGTACTTCTTTAGATGTGGAGCCTATCTACACCTTCAGGGCTCACAAAGGTCCGGTGCTG
TGTGTGGTCATGAGTAGCAATGGTGAGCAGTGCTACAGCGGCGGCACTGATGGCCTCATCCAGA
GCTGGAGCACCACCAATCCCAACGTCGACCCCTACGATTCTTATGATCCTTCGGTTCTAAGAGG
CCCTCTGTTGGGCCACACGGATGCGGTGTGGGGGCTGGCCTACAGCGCGGCCCACCAGCGCTTG
TTGTCCTGTTCAGCAGACGGCACTCTTCGTCTATGGACCACCACTGAGGTTGCTCCAGCGCTGA
CTGTATTTAATGATAACCAAGAACTGGGAATCCCTGCTTCTGTGGATCTGGTGAGCAGTGACCC
GAGCCATATGGTAGCATCGTTCAGCAAGGGATATACAAGCATCTTCAACATGGAAACACAGCAG
CGAATTCTCACGTTAGAATCCAATGTCGATTCAACGGCCAGTTCTTCCTGCCAAATAAACAGAG
TCATCAGTCACCCCACCCTCCCGATCAGCATCACTGCTCACGAGGACAGGCACATCAAGTTCTA
CGATAACAACACAGGCAAACTGATCCACTCGATGGTGGCCCACCTGGAAGCCGTTACAAGTTTG
GCGGTTGATCCCAACGGCCTGTACCTGATGTCTGGCAGTCATGACTGTTCAATACGCTTGTGGA
ATTTAGAAAGTAAGACGTGTATCCAGGAGTTCACAGCTCATCGGAAAAAGTTTGAAGAGTCGAT
CCATGATGTAGCATTCCACCCTTCTAAATGCTATATAGCCAGCGCTGGAGCCGACGCCCTGGCT
AAGGTCTTTGTATGATGGGGTACTTCAGCTTCACCCTGCAGCTCTTACAAGTCAACCGCACACA
GGAAACGGAAGACCAGGGCGGGAGCCAGCTCGCCCTGCCCTTTTGTTTGGCTGAGGGAGCACAG
AGACCTCTGTTAAAGTACAGTTTTGCAGTTCCTATACAGTTTTCTAAAATTAAGGTTTGTTCAG
GTTGCTGCAAGCTCAGCTGAACCTGTGAGCCCGAAACTTTCAGATCCCCCCAAAGAGGCACTTT
TATTTCTGAGGTTGTTCTCACTCGCTAGGCGGGCCCGAGCGTTCGTTCTCCCTTTTGAGTAAGC
AGGGCATGCTGTAATGGATAATTAGAGGTGAATGCCGGGAATGAGTAGAATGGAAACTTAACTA
TCCTTCCACCCCGAGACATCTGCTACCACACTAGGTAGTCAGCTCTGCGGCTGTGTGTGCTCTA
CTAACCCCACTGTGTAGAAGGAGACAGTGTGTGTCAGTGTTCACATGAGGTCCTCCCGCTGCTG
TCCTCTCAGCCGTTCTCATGAAGCACAGGGAAGAGTGTTCCTTCCACCTGTTAGGAGGAAGAGA
TGCAATAATATGTTAATTATATGATATTCAGAAATGCTAAACAAATACTTAATTTGCAAGCAAA
TTTCTATATTGTATTACAATTTTGAAAGTAGATATGGAACATTCTAAAGTTTAGCTGTGAGGCA
CTCGCAGTCAGGAATGGTGAATGGAGTCTGCTTTTACTAAAGGTGTTTAACTCATCCAGGTTTG
AGATCCTGTTTATTTTTAAGGGCAAACAGGGCATATTTCTACAATTTGTCTAAAACTTCACCTC
ATTAATGTACTAGAGTGATCATTTCAATTGATAAATTTACTTCCTAGTGACTCTCTGCCAAAGG
AGAAAACTTTATTAGCATCCGTTTCCCAGCACCCATACAACTGGTTCAACCGATCTTCACTGTT
TCTAACCTGCCCCTCACCTTCATGTTGTCTGATGCTTACCATAGACAGTTTATAATGACTGTGT
CATGTAGTCCAAAGCACGTGGTCACCTCAGGCAGCTGCTTTTGCAACTGCACTTGGTAAAGCAG
TGCACCCCAGCATGTCCTCAGTAGTGTCTCGAAAAAGAACTCTGTGGAGATCTAGATGGAGATG
TTAGTACCTGTGATGTCTTCAAGGTTCTTTCTCCTCCCCTCTCTGCATTGTTTAATTGGAACAC
ACATTTTAATGAACAGTTGATCAATACTGTATCCAGAGAAAACCATGTCCTAAAATGGTCAGCT
TGTGGAAGTCTCAGAATCCTGCTGACTCAACCAAAGGCAGCCTCATACCCTTCACACCCTCTCT
ACCTCTGTCCTAAATGACAGAGACCACTATAAATAATACATTCAAATTAATCTCCATCCTTTTT
ATCAAAATGTGTACACCATGGGCTCTCTGTCTTAAAAATACTATACCCATAAATATTATGAGCC
ATTAAAATAATTCCATTGCCATAGCCATGGCTTTTCTGGTGATCTGTTCTTTGAAGTGGATTCT
CATGGTGATATGGTTAATAATTGACTTCTTAAAGTTTTCTGCTCATCTGTCTTTAGAATTCCCC
AGTGCAGGCAGACTTTTACTACTACATTGTAAGACTCCTGTTGAAGTTCCCTGATTATTGTATA
GACAGCTGTAGTAGTTAACACAACTGCTGTTTATCCTTGTGCTTTGGTTAACAAGCAGACTTAA
GAGATGGATTGGTATATGCAGGTGAATTGAGTTACACCTAACTACCAGGCAAATCCTCATGCAG
ATAGAGTTTTACGTTGTGACGGGTAAATTCTTCCATTCTTTGTGAAATGAACAGAAGGATTTGT
TAACATGTGTAGAATATTAGAAGATTCCAGTCAGAATTGGCATAGTTATGATGGCTGACCACAG
AAACTGCTTCAGTTACTTTCCAGTCTTCGGTGTGTCTTACTCTCGTCCCCAGCGCTCCAGAACC
CAGGAGAATCTGCCCTGTTCGCTCTGCCTCGTGAGATTGAAGTTCTCCTGTTACTGGGTGGGAA
ATTGTCCTAAGATAGGCAAAGTGTGATGAACTGGCAGAACTGCTGTAAGGCTTTAGGAAGTGTG
CTTTGTGCCACTGAAGACTGCACATAGAGAGAGTCCTCCAAACCCGCCCTGTTCGCTGTCATCC
TAGAAATGAGCCAAAGCGGTCTTCCAACTGGATGGTAGCATGGACACGTGTTTGACTTTCCCCA
TCCTATTGAAAAGTCACAAGACGAGCAATTTCAAGATTCAAAATCCTTGAAATACTTTGATGAA
TACTTACCAGATTGTAACGTCTCGGGCGAGCTGCTCTGGAATGGAGACTTGGAAGTCAGCAGGT
AGGCTAGGGCCCTGCCTCGCTCTCTTGTGCTGTGGATGTGACTCGGGGCTTCCAGTGCTTCTCC
AGGTGCAGCTGTGACTCAGAGCTCATTCGCTACTCAAACCATAGACACGTAGGTGATGGATGAC
CTTCAGTATTTTTGTATTGAACAAAGTTATCAATTTTTGCCATTAAACAGATAATTAGTTATGC
AAAATATTTAGCTTTTGTAACCATTTAGTTGTAACTGAGAGGGGGATTGAACTGTACCACTGAT
AATGAACTTGGTGAGAAATTATTTGTTTATCTGACTTCATTCCTTCAGTATTCTTGCTATAAAT
TTCTTTTGGAGATAATGATTCTTTATTTGAAAGATGTCTAAAATGTATGTATATTTTATAAATA
TATATTATATATATTATAGGGATATATATAATATATAGACTATATATATCTATCTAAACCATGG
GTGCATTGTACTGTTTGCGTCTTCACTTTCGGAGGTAGTATGCTCACAAGTTGATGAGTCTGGC
GACTGTTGTGCTGTTTGCTTTTACAGTGTAATATATAGTTCCAAGTGTTTAAATACTGTATATA
CTATATTCATTATAGGCTAGCATGCTTGTTTTAAAGACTGTCATTCTAGTTTATTAAAATCTGA
ATGTAAGAAAACCTGGCTATTCAAATGTGAATTGAAAAAATTCCATTCTCAGAACTGAACTATT
TCCATATAACTGAACATTCAAGCTTTTTGACAAAATGTGTCATCGAGAAGGCAATAGCTAGAAA
GTGAGAGGTGCCTTTAAAAAATCCTACAAATGCAGCCTTACAGTGAGGGTGAAGATTGAATCTG
TGTCAGGGGGTGGGAGGGGGAAGAGAGTGTGTGAGAGATGGTGTGTGTGTGTGTGTGTGTGTGT
GTGTGTGTGTGTGTGTGTATGCGCGTGTGTGTGCGCATGCGCGCACGGACGCACCAATCTGTGA
AGATCCTGATTTGTGATTGTCAGTGTCGTTTAATATATCTGTTCAACTTCTAGGACTTGAGGGG
TCATCTCCATATAGTTGCCGTACTCCTTCGAGCACTTTCTGTGCTTTCCAAGAGTTTTGAATGT
GAACTCCTAGAAAATTCACTAAAGAATAAATAGCTCCTTTTTTTAAAAATCAATCTCAGATAAC
AAATTATTGGTTCCCTGGAATTATGGGCTTCTCGCTGATACTGTAATTTTGTAAACCTTGACTT
TCTAGTGCTTCGTGTGTTTCCCCTGTTCACAAGAGTATGGCATAAAGTTGTTAGATGATGAGGA
TTGGTCTAGTAAATCTCGCTCTTAGATGAAACACTTGAACTAACTCAACTCCACCTAACAGTAG
TCGTGAAGACCTGAAACGGCCTCTCATATCTACCTCATGGTCATTGCTGCCATCCTAAGTAGAA
CAGCGGTCTGCATTACAGATAATAGTCGATGCAGCTTAATCATCTGTCGGTGCTTTTCTCGGGC
TGTGTCATCTCAGCTGCACGCCACAGAGCAGCTTGTAACATTCGGGCTAGTTTAGGTCTGTCGC
TTGTTTCCTTTGTTTTGTTTTCCTAAGGACGGCTTTAAAATACTATCAGTGTACTTTTTCGGAG
GGAGTTGGTTCCCGGTTGTTATGTCTGTGAAATATATATATATTTTTTTTGGTTCTTTTTTTCG
GAGCTGGGGACCGAACCCAGGGCCTTGCGCTTCCTAGGCAAGCGCTCTACCACTGAGCTAAATC
CCCAGCCCCTTGTGAAATATTTTTAACCAAGAATCAGATCGTTAGTGAATTTACCTGAAACTCC
AGCCATAGACACTCTTATGTAATCCAACCAATTGAAAGGTGAAGGCAAGAGAATCACAAGTTCA
AGATCATCCTCAGCTGTATAAGGAGCTCAAGGCCAGCCTGGGCTACACAAGGCCAGCCTGGACT
ACACGAACCCTTGTCTCAATACAACAAGAAGTGTACCTGGAAAGGGAAGTCTAGTTTTATTTGG
CTTACTTTATTCTTGAAAGGCATTTCAACGCTCTTAGGTATATAATTATTCACCTTACTGACTT
AGAAAATGCCTCTCTAAGCCTGCTACTTCTTTGTTTATATTTCAGTACTTAGAATGTTTGACAC
TGGGATTCTGGTTGCACAAAAGTAGTATCAGATGAAGTGTGTGTGTGTGTGTGTGTGTGTGTGT
GTGTGTGTGTGTGTGTGTGTGTGTGAGAGAGAGAGGGGGGGGTGGTGGGGAGAGTGTGAGATGG
GGGGAGAGAGAGAATGTGTGTGTGAAATACATTATTTCTTAAAGTCCATTTCAGTGGAAGGCCA
GAGGATGAGTATATCTGTTTAGCAGGTAAACAATGTGAATCAGTGTCCACATCAGGCCTGTAGT
TAGGTCTCTGTGTCCATGGAAGGGACCCCACATTGACCAAGTGTTTAACAGAACCTTTACATCA
GTTTTATTGCTATGAGTTTAATGTTGAGAGGATTACGTCAGACCAAAGGAGAGCTTTAGACCCA
CCCTTTATTCTAACGATGTTCCTGAAGCAGTGCTGAAGATTTTTTTTTTTCTGGATTTTTCTGG
ATCTTGGCTAGTCAAGGTTTAGGTGTCATTTAACTGGGACCACATGCTCATCATCCCTCTGGTG
CAAATTAGAGAGTTCATGTTGATTTAGACTAACTTTAATGTCTGCCTGGGTGTTTACCAGGCTG
TGAACCAGTGAGTGCCTTGTTAGTGTAGCGTGATTTACCCGTTGTGCGTTAGGTCTTTCTGAGG
GTCTCAGACTGAGCTTCGAGCTGGCTGTGGCGAGCTGCGGAGATTAGGAACGCAGCATTAGGAG
GTCTTCGGTCTGCCATGTCCACTCCCCTGCTTTCTCTTCAGTGTTTGGCTGGTGTTGGCCCTTG
TGAGAAAACAAGTAGAGCCCTCTTCACACTTTTTTTCTTTTTTATTCCCGATTGAGGAGTGTCC
CCCATTCCCACCCCGGCTATATGATCAAATGCCTGTTTTAGGAAGAACCACTTCTTTGTAATAC
TAAAACCTACCACTTACCTTATGTCTTCTCAGTATCAGTTTACTGGAGCGGATCTCAGGGTGTC
ATCAGTTCAGATTCCTAAATAACCCGTTCCCTCCAGCCCAAACCCCAACTGGTGAGCCCTGAGC
CAGATCGTTTGATATTCAGGTATCTTCAACTTTAGTTACAATATCAATTAATGTAAATCCAAAT
GCGGATTCGTGTGGTGCAAGCAGTGTCTTTGTAAATCCAGGGTGTGGATAAGCTAACTGATATC
CAGTTTTGGTGGCTCTAAGTGTATTATTTGTTTTTAAATAAAGTGTACAAACATAGT

hide sequence

RefSeq Acc Id:

XM_039111825 ⟹ XP_038967753

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	6	22,135,936 - 22,174,284 (+)	NCBI
mRatBN7.2	6	16,384,649 - 16,422,159 (+)	NCBI

Protein Sequences


Protein RefSeqs	NP_062021	(Get FASTA)	NCBI Sequence Viewer
	XP_006239684	(Get FASTA)	NCBI Sequence Viewer
	XP_038967753	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000006527
	ENSRNOP00000093598
GenBank Protein	P70483	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

NP_062021 ⟸ NM_019148

- UniProtKB:

P70483 (UniProtKB/Swiss-Prot), G3V6L8 (UniProtKB/TrEMBL), A6H9V7 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MDEQAGPGVFFSNNHPGAGGAKGLGPLAEAAAAGDGAAAAGAARAQYSLPGILHFLQHEWARFE
VERAQWEVERAELQAQIAFLQGERKGQENLKKDLVRRIKMLEYALKQERAKYHKLKYGTELNQG
DMKPPSYDSDEGNETEVQPQQNSQFMWKQGRQLLRQYLQEVGYTDTILDVKSKRVRALLGFSSD
VTDREDDKNQDSVINGTEAEVKETAMIGKSELTDSASVLDNFKFLENAAADFSDEDEDEDIDGR
EKSVIDTSTIVRKKPLPDTSEDRDTKEALKEFDFLVASEEGDNESRSAGDGTDWEKEDQCLTPE
RWNVDQGVITRLKEQYKKERKGKKGVKRPNRSKLQDMLANLRDVDELPSLQPSVGSPSRPSSSR
LPEQDISRADEVEALTFPPSSGKSFIMGADEALESELGLGELAGLTVANEADSLAYDIANNKDA
LRKTWNPKFTLRSHFDGIRALAFHPIEPVLITASEDHTLKMWNLQKTAPAKKSTSLDVEPIYTF
RAHKGPVLCVVMSSNGEQCYSGGTDGLIQSWSTTNPNVDPYDSYDPSVLRGPLLGHTDAVWGLA
YSAAHQRLLSCSADGTLRLWTTTEVAPALTVFNDNQELGIPASVDLVSSDPSHMVASFSKGYTS
IFNMETQQRILTLESNVDSTASSSCQINRVISHPTLPISITAHEDRHIKFYDNNTGKLIHSMVA
HLEAVTSLAVDPNGLYLMSGSHDCSIRLWNLESKTCIQEFTAHRKKFEESIHDVAFHPSKCYIA
SAGADALAKVFV

hide sequence

RefSeq Acc Id:	XP_006239684 ⟸ XM_006239622
- Peptide Label:	isoform X1
- UniProtKB:	P70483 (UniProtKB/Swiss-Prot), A0A8I6AG38 (UniProtKB/TrEMBL)
- Sequence:	show sequence MDEQAGPGVFFSNNHPGAGGAKGLGPLAEAAAAGDGAAAAGAARAQYSLPGILHFLQHEWARFE VERAQWEVERAELQAQIAFLQGERKGQENLKKDLVRRIKMLEYALKQERAKYHKLKYGTELNQG DMKPPSYDSDEGNETEVQPQQNSQFMWKQGRQLLRQYLQEVGYTDTILDVKSKRVRALLGFSSD VTDREDDKNQDSVINGTEAEVKETAMIGKSELTDSASVLDNFKFLENAAADFSDEDEDEDIDGR EKSVIDTSTIVRKKPLPDTSEDRDTKEALKEFDFLVASEEGDNESRSAGDGTDWEKEDQCLTPE AWNVDQGVITRLKEQYKKERKGKKGVKRKTTEDLFQPLSYIKQSKQGCGRMKKQSPGPNRSKLQ DMLANLRDVDELPSLQPSVGSPSRPSSSRLPEQDISRADEVEALTFPPSSGKSFIMGADEALES ELGLGELAGLTVANEADSLAYDIANNKDALRKTWNPKFTLRSHFDGIRALAFHPIEPVLITASE DHTLKMWNLQKTAPAKKSTSLDVEPIYTFRAHKGPVLCVVMSSNGEQCYSGGTDGLIQSWSTTN PNVDPYDSYDPSVLRGPLLGHTDAVWGLAYSAAHQRLLSCSADGTLRLWTTTEVAPALTVFNDN QELGIPASVDLVSSDPSHMVASFSKGYTSIFNMETQQRILTLESNVDSTASSSCQINRVISHPT LPISITAHEDRHIKFYDNNTGKLIHSMVAHLEAVTSLAVDPNGLYLMSGSHDCSIRLWNLESKT CIQEFTAHRKKFEESIHDVAFHPSKCYIASAGADALAKVFV hide sequence

Ensembl Acc Id:

ENSRNOP00000006527 ⟸ ENSRNOT00000006527

RefSeq Acc Id:	XP_038967753 ⟸ XM_039111825
- Peptide Label:	isoform X2

Ensembl Acc Id:

ENSRNOP00000093598 ⟸ ENSRNOT00000118929

Ensembl Acc Id:

ENSRNOP00000112827 ⟸ ENSRNOT00000172485

Protein Domains

Striatin N-terminal

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-P70483-F1-model_v2	AlphaFold	P70483	1-780	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13694351

Promoter ID:

EPDNEW_R4876

Type:

multiple initiation site

Name:

Strn_1

Description:

striatin

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	6	1,319,515 - 1,319,575	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:3782	AgrOrtholog
BioCyc Gene	G2FUF-38485	BioCyc
Ensembl Genes	ENSRNOG00000004806	Ensembl, ENTREZGENE
Ensembl Transcript	ENSRNOT00000006527	ENTREZGENE
	ENSRNOT00000118929	ENTREZGENE
Gene3D-CATH	1.20.5.300	UniProtKB/Swiss-Prot
	2.130.10.10	UniProtKB/Swiss-Prot
InterPro	G-protein_beta_WD-40_rep	UniProtKB/Swiss-Prot
	Striatin_N	UniProtKB/Swiss-Prot
	WD40/YVTN_repeat-like_dom_sf	UniProtKB/Swiss-Prot
	WD40_repeat	UniProtKB/Swiss-Prot
	WD40_repeat_CS	UniProtKB/Swiss-Prot
	WD40_repeat_dom_sf	UniProtKB/Swiss-Prot
	WD_repeat_striatin	UniProtKB/Swiss-Prot
KEGG Report	rno:29149	UniProtKB/Swiss-Prot
NCBI Gene	29149	ENTREZGENE
PANTHER	STRIATIN	UniProtKB/Swiss-Prot
	STRIATIN	UniProtKB/Swiss-Prot
Pfam	Striatin	UniProtKB/Swiss-Prot
	WD40	UniProtKB/Swiss-Prot
PhenoGen	Strn	PhenoGen
PRINTS	GPROTEINBRPT	UniProtKB/Swiss-Prot
PROSITE	WD_REPEATS_1	UniProtKB/Swiss-Prot
	WD_REPEATS_2	UniProtKB/Swiss-Prot
	WD_REPEATS_REGION	UniProtKB/Swiss-Prot
RatGTEx	ENSRNOG00000004806	RatGTEx
SMART	WD40	UniProtKB/Swiss-Prot
Superfamily-SCOP	SSF50978	UniProtKB/Swiss-Prot
TIGR	TC239681
UniProt	A0A8I6AG38	ENTREZGENE, UniProtKB/TrEMBL
	A0ABK0MA30_RAT	UniProtKB/TrEMBL
	A6H9V7	ENTREZGENE, UniProtKB/TrEMBL
	G3V6L8	ENTREZGENE, UniProtKB/TrEMBL
	P70483	ENTREZGENE, UniProtKB/Swiss-Prot

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2015-12-02	Strn	striatin	Strn	striatin, calmodulin binding protein	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2004-09-10	Strn	striatin, calmodulin binding protein		striatin	Name updated	1299863	APPROVED
2002-06-10	Strn	striatin			Name updated	70584	APPROVED

RGD Curation Notes

Note Type	Note	Reference
gene_cellular_localization	localized to the plasma membrane	70027
gene_process	may be involved in neuronal excitatory Ca(++)-signaling pathways	70027
gene_product	member of WD repeat family	70027

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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