Sult1a1 (sulfotransferase family 1A member 1) - Rat Genome Database

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Gene: Sult1a1 (sulfotransferase family 1A member 1) Rattus norvegicus
Analyze
Symbol: Sult1a1
Name: sulfotransferase family 1A member 1
RGD ID: 3767
Description: Enables 3'-phosphoadenosine 5'-phosphosulfate binding activity; aryl sulfotransferase activity; and identical protein binding activity. Involved in several processes, including 4-nitrophenol metabolic process; estrogen metabolic process; and sulfation. Predicted to be active in cytoplasm. Human ortholog(s) of this gene implicated in several diseases, including breast cancer; gastrointestinal system cancer (multiple); lung cancer (multiple); reproductive organ cancer (multiple); and urinary bladder cancer. Orthologous to several human genes including SULT1A1 (sulfotransferase family 1A member 1); SULT1A3 (sulfotransferase family 1A member 3); and SULT1A4 (sulfotransferase family 1A member 4); PARTICIPATES IN lamivudine pharmacokinetics pathway; paracetamol pharmacokinetics pathway; sulfite oxidase deficiency pathway; INTERACTS WITH (+)-schisandrin B; (S)-naringenin; 1,2-dimethylhydrazine.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: Aryl sulfotransferase cytosolic 1A phenol-preferring member 3; Aryl sulfotransferase cytosolic, 1A, phenol-preferring, member 3; aryl sulfotransferase IV; ASTIV; minoxidil sulfotransferase; Mx-ST; Phenol sulfotransferase 1a1; PST-1; St1a1; Stm; Stp1; sulfokinase; sulfotransferase 1A1; sulfotransferase family 1A, phenol-preferring, member 1; sulfotransferase family cytosolic 1A phenol preferring; sulfotransferase family, cytosolic, 1A, phenol preferring; sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1; sulphotransferase family cytosolic 1A phenol-prefering member 1; sulphotransferase family, cytosolic, 1A, phenol-prefering, member 1; Sult1a3; tyrosine-ester sulfotransferase
RGD Orthologs
Human
Bonobo
Dog
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Is Marker For: Strains:   SD-Del(Sult1a1-Spn)/YahIcsOrl ; SD-Dp(Sult1a1-Spn)/YahIcsOrl
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81190,702,592 - 190,706,112 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1190,702,592 - 190,706,131 (-)EnsemblGRCr8
mRatBN7.21181,272,022 - 181,276,750 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1181,272,023 - 181,275,562 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1189,623,229 - 189,626,764 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01196,809,299 - 196,812,834 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01189,476,705 - 189,480,237 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01198,100,586 - 198,104,106 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1198,100,586 - 198,104,109 (-)Ensemblrn6Rnor6.0
Rnor_5.01205,079,585 - 205,083,105 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41185,829,205 - 185,832,725 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1178,929,499 - 178,933,019 (-)NCBICelera
RGSC_v3.11185,979,085 - 185,982,606 (-)NCBI
Cytogenetic Map1q36NCBI
JBrowse:




Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-catechin  (ISO)
(+)-schisandrin B  (EXP)
(S)-naringenin  (EXP,ISO)
(S)-ropivacaine  (ISO)
1,2-dimethylhydrazine  (EXP)
1-aminobenzotriazole  (ISO)
1-Hydroxypyrene  (ISO)
1-Methylpyrene  (ISO)
1-naphthol  (ISO)
11-deoxycorticosterone  (EXP)
17alpha-ethynylestradiol  (EXP,ISO)
17beta-estradiol  (EXP,ISO)
2,2',4,4',5,5'-hexachlorobiphenyl  (EXP)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,2',4,5-tetrachlorobiphenyl  (ISO)
2,2',5,5'-tetrachlorobiphenyl  (ISO)
2,3,4,5-tetrachlorophenol  (ISO)
2,3,4,6-tetrachlorophenol  (ISO)
2,3,5,6-tetrachlorophenol  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4,5-trichlorophenol  (ISO)
2,4,6-tribromophenol  (ISO)
2,4,6-trichlorophenol  (ISO)
2,4,6-trinitrotoluene  (EXP)
2,4-dichlorophenol  (ISO)
2,5-dihydroxybenzoic acid  (EXP,ISO)
2,6-dinitrotoluene  (EXP)
2-Amino-3-methyl-9H-pyrido[2,3-b]indole  (ISO)
2-amino-4,6-dinitrotoluene  (EXP)
2-Amino-9H-pyrido[2,3-b]indole  (ISO)
2-chlorophenol  (ISO)
2-hydroxy-17beta-estradiol  (ISO)
2-methoxy-17beta-estradiol  (ISO)
2-methylcholine  (ISO)
2-naphthylamine  (ISO)
3'-phospho-5'-adenylyl sulfate  (ISO)
3,3',4,4',5-pentachlorobiphenyl  (EXP)
3,3',5'-triiodo-L-thyronine  (ISO)
3,3',5,5'-tetrabromobisphenol A  (ISO)
3,3',5-triiodo-L-thyronine  (ISO)
3,3'-diiodothyronine  (ISO)
3-Amino-1-methyl-5H-pyrido[4,3-b]indole  (ISO)
3-chlorophenol  (ISO)
3-chloropropane-1,2-diol  (EXP)
3-Hydroxybenzo[a]pyrene  (ISO)
3-methylcholanthrene  (EXP,ISO)
3-Nitrobenzanthrone  (ISO)
4-chlorobiphenyl  (ISO)
4-chlorophenol  (ISO)
4-Hydroxy-N-desmethyltamoxifen  (ISO)
4-hydroxybenzoic acid  (ISO)
4-methylumbelliferone  (EXP,ISO)
4-nitrophenol  (EXP,ISO)
4-nonylphenol  (ISO)
4-octylphenol  (ISO)
5-hydroxyindole  (EXP,ISO)
5-hydroxymethylfurfural  (EXP,ISO)
5-Hydroxytryptophol  (EXP,ISO)
6-hydroxymelatonin  (EXP,ISO)
6-propyl-2-thiouracil  (EXP)
7,12-dimethyltetraphene  (EXP)
acetonitrile  (ISO)
actinomycin D  (ISO)
adenosine 3',5'-bismonophosphate  (EXP)
afimoxifene  (ISO)
aflatoxin B1  (ISO)
all-trans-retinoic acid  (ISO)
Aloe emodin  (ISO)
alpha-Zearalanol  (EXP)
amitrole  (EXP)
ammonium chloride  (EXP)
anthra[1,9-cd]pyrazol-6(2H)-one  (ISO)
apigenin  (ISO)
aristolochic acid A  (ISO)
Aroclor 1254  (EXP)
arsenous acid  (ISO)
benzene  (ISO)
benzo[a]pyrene  (EXP,ISO)
benzo[a]pyrene-7,8-dione  (ISO)
benzo[e]pyrene  (ISO)
benzyl alcohol  (ISO)
beta-naphthoflavone  (EXP,ISO)
bexarotene  (EXP)
biochanin A  (EXP)
biphenyl-4-amine  (ISO)
bis(2-ethylhexyl) phthalate  (EXP)
bisphenol A  (EXP,ISO)
bisphenol AF  (ISO)
Bisphenol B  (ISO)
bisphenol F  (ISO)
Butylbenzyl phthalate  (EXP)
butyric acid  (ISO)
cadmium acetate  (EXP)
cafestol  (ISO)
caffeine  (EXP)
carbamazepine  (EXP)
carbonyl sulfide  (EXP)
catechol  (ISO)
chrysin  (ISO)
chrysophanol  (ISO)
cis-caffeic acid  (ISO)
cisplatin  (ISO)
clofibrate  (EXP)
clotrimazole  (EXP)
cobalt dichloride  (EXP)
copper atom  (EXP)
copper(0)  (EXP)
corticosterone  (EXP)
crocidolite asbestos  (ISO)
cycloheximide  (ISO)
cyclosporin A  (ISO)
cylindrospermopsin  (ISO)
daidzein  (ISO)
decabromodiphenyl ether  (ISO)
deguelin  (ISO)
deoxynivalenol  (ISO)
dexamethasone  (EXP)
diarsenic trioxide  (ISO)
Dibutyl phosphate  (ISO)
diethyl maleate  (EXP)
diethylstilbestrol  (EXP,ISO)
dimethyl sulfoxide  (ISO)
dioxygen  (ISO)
diuron  (EXP)
dopamine  (EXP,ISO)
dorsomorphin  (ISO)
doxorubicin  (ISO)
emodin  (ISO)
endosulfan  (EXP)
entinostat  (ISO)
estrone  (ISO)
ethanol  (EXP,ISO)
ethyl methanesulfonate  (ISO)
felbamate  (EXP)
fenbuconazole  (ISO)
ferulic acid  (EXP)
fipronil  (EXP,ISO)
flavonoids  (ISO)
folic acid  (ISO)
formaldehyde  (ISO)
furan  (EXP)
furfuryl alcohol  (EXP,ISO)
gabapentin  (EXP)
gallic acid  (EXP,ISO)
gamma-hexachlorocyclohexane  (EXP)
genistein  (ISO)
gentamycin  (EXP)
Glu-P-1  (ISO)
Glu-P-2  (ISO)
glutathione disulfide  (EXP)
glycidyl methacrylate  (ISO)
harmol  (EXP,ISO)
heptachlor  (EXP)
hexachlorobenzene  (EXP)
hydrogen peroxide  (ISO)
indometacin  (EXP)
iodide salt  (EXP)
kahweol  (ISO)
ketamine  (EXP)
kojic acid  (EXP)
L-ascorbic acid  (ISO)
lead diacetate  (EXP)
lidocaine  (ISO)
lithium atom  (ISO)
lithium hydride  (ISO)
m-xylene  (EXP)
meclofenamic acid  (ISO)
mefenamic acid  (EXP,ISO)
mercury dibromide  (ISO)
methamphetamine  (EXP)
methanol  (ISO)
methapyrilene  (EXP,ISO)
methimazole  (EXP)
methotrexate  (ISO)
methyl methanesulfonate  (ISO)
mifepristone  (EXP)
minoxidil  (EXP,ISO)
N,N-diethyl-m-toluamide  (ISO)
N,N-dimethylformamide  (ISO)
N-Desmethyltamoxifen  (ISO)
N-hydroxy-4-aminobiphenyl  (ISO)
N-hydroxy-PhIP  (ISO)
N-methyl-4-phenylpyridinium  (EXP)
N-nitrosodiethylamine  (EXP)
N-nitrosodimethylamine  (ISO)
N-nitrosomorpholine  (EXP)
NADP zwitterion  (ISO)
NADP(+)  (ISO)
naphthalene  (EXP)
neoglucobrassicin  (ISO)
nevirapine  (EXP)
nickel dichloride  (EXP)
nimesulide  (ISO)
nitrofen  (EXP,ISO)
Nivalenol  (ISO)
ochratoxin A  (EXP)
okadaic acid  (ISO)
oxaliplatin  (EXP)
oxybenzone  (EXP)
oxycodone  (EXP)
p-chloromercuribenzoic acid  (ISO)
p-cresol  (EXP)
panobinostat  (ISO)
paracetamol  (EXP,ISO)
paraquat  (EXP)
parathion  (EXP)
pentachlorophenol  (ISO)
perfluorodecanoic acid  (EXP)
perfluorooctane-1-sulfonic acid  (EXP)
perfluorooctanoic acid  (EXP)
phenobarbital  (EXP,ISO)
phenols  (EXP)
phentolamine  (EXP,ISO)
phenylmercury acetate  (ISO)
phenytoin  (EXP)
PhIP  (EXP,ISO)
physcion  (ISO)
picoxystrobin  (ISO)
pinocembrin  (EXP,ISO)
pirinixic acid  (EXP)
piroxicam  (ISO)
pregnenolone 16alpha-carbonitrile  (EXP)
progesterone  (EXP)
quercetin  (ISO)
resveratrol  (ISO)
Rhein  (ISO)
rotenone  (EXP,ISO)
salicylamide  (EXP,ISO)
SB 203580  (ISO)
SB 431542  (ISO)
scopolamine  (EXP)
serotonin  (EXP,ISO)
sevoflurane  (EXP)
sodium arsenite  (ISO)
sodium chloride  (ISO)
sodium dichromate  (EXP)
sulfadimethoxine  (EXP)
sunitinib  (ISO)
tamoxifen  (ISO)
tauroursodeoxycholic acid  (EXP)
tetrachloromethane  (EXP)
thioacetamide  (EXP)
thiram  (ISO)
thyroxine  (ISO)
titanium dioxide  (EXP)
toluene 2,4-diisocyanate  (ISO)
topotecan  (EXP)
trans-caffeic acid  (ISO)
triamcinolone acetonide  (EXP)
trichloroethene  (EXP)
trichostatin A  (ISO)
triclosan  (ISO)
triphenyl phosphate  (EXP,ISO)
troglitazone  (EXP,ISO)
umbelliferone  (EXP,ISO)
ursodeoxycholic acid  (EXP)
valdecoxib  (EXP)
valproic acid  (EXP,ISO)
vincaleukoblastine  (ISO)
vinclozolin  (EXP)
xanthohumol  (ISO)
zaragozic acid A  (EXP)
zinc atom  (EXP)
zinc sulfate  (EXP)
zinc(0)  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytoplasm  (IBA,IEA)

References

References - curated
# Reference Title Reference Citation
1. Phenol sulphotransferase SULT1A1*1 genotype is associated with reduced risk of colorectal cancer. Bamber DE, etal., Pharmacogenetics. 2001 Nov;11(8):679-85.
2. Sulfotransferase 1A1 polymorphism and gastric cancer risk: a pilot case-control study. Boccia S, etal., Cancer Lett. 2005 Nov 18;229(2):235-43. Epub 2005 Aug 30.
3. Phenol sulfotransferase. I. Purification of a rat liver enzyme by affinity chromatography. Borchardt RT and Schasteen CS, Biochim Biophys Acta. 1982 Nov 19;708(3):272-9.
4. Genetic polymorphisms of SULT1A1 and SULT1E1 and the risk and survival of breast cancer. Choi JY, etal., Cancer Epidemiol Biomarkers Prev. 2005 May;14(5):1090-5.
5. Human thyroid phenol sulfotransferase enzymes 1A1 and 1A3: activities in normal and diseased thyroid glands, and inhibition by thyroid hormones and phytoestrogens. Ebmeier CC and Anderson RJ, J Clin Endocrinol Metab. 2004 Nov;89(11):5597-605.
6. Transactivation of glucocorticoid-inducible rat aryl sulfotransferase (SULT1A1) gene transcription. Fang HL, etal., Drug Metab Dispos. 2003 Nov;31(11):1378-81.
7. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
8. Use of genetically manipulated Salmonella typhimurium strains to evaluate the role of sulfotransferases and acetyltransferases in nitrofen mutagenicity. Glatt H and Meinl W, Carcinogenesis. 2004 May;25(5):779-86. Epub 2004 Jan 30.
9. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
10. Comparative analysis of SNP in estrogen-metabolizing enzymes for ovarian, endometrial, and breast cancers in Novosibirsk, Russia. Gulyaeva LF, etal., Adv Exp Med Biol. 2008;617:359-66.
11. CYP1A1, SULT1A1, and SULT1E1 polymorphisms are risk factors for endometrial cancer susceptibility. Hirata H, etal., Cancer. 2008 May 1;112(9):1964-73.
12. Sequence analysis, in vitro translation, and expression of the cDNA for rat liver minoxidil sulfotransferase. Hirshey SJ, etal., Mol Pharmacol 1992 Aug;42(2):257-64.
13. Enzymatic characterization and interspecies difference of phenol sulfotransferases, ST1A forms. Honma W, etal., Drug Metab Dispos. 2001 Mar;29(3):274-81.
14. Sulfotransferase 1A2*2 is a risk factor for early-onset breast cancer. Hou MF, etal., Int J Mol Med. 2002 Nov;10(5):609-12.
15. [Study on the relationship between polymorphisms of genes (CYP17, CYP19 and SULT1A1) and susceptibility to breast cancer in Chinese women] Hu MB, etal., Zhonghua Liu Xing Bing Xue Za Zhi. 2006 Apr;27(4):351-5.
16. Sulfotransferase1A1 and risk of postmenopausal breast cancer. Jerevall PL, etal., Anticancer Res. 2005 May-Jun;25(3c):2515-7.
17. KEGG: Kyoto Encyclopedia of Genes and Genomes KEGG
18. Further evidence for null association of phenol sulfotransferase SULT1A1 polymorphism with prostate cancer risk: a case-control study of familial prostate cancer in a Japanese population. Koike H, etal., Int Urol Nephrol. 2008 Mar 27.
19. Epigenetic silencing of the sulfotransferase 1A1 gene by hypermethylation in breast tissue. Kwon MS, etal., Oncol Rep. 2006 Jan;15(1):27-32.
20. Genetic variants of the sulfotransferase 1A1 and breast cancer risk. Langsenlehner U, etal., Breast Cancer Res Treat. 2004 Sep;87(1):19-22.
21. A functional polymorphism in the SULT1A1 gene (G638A) is associated with risk of lung cancer in relation to tobacco smoking. Liang G, etal., Carcinogenesis. 2004 May;25(5):773-8. Epub 2003 Dec 19.
22. Stress regulation of sulfotransferases in male rat liver. Maiti S, etal., Biochem Biophys Res Commun. 2004 Oct 8;323(1):235-41.
23. In vivo and in vitro oxidative regulation of rat aryl sulfotransferase IV (AST IV). Maiti S, etal., J Biochem Mol Toxicol. 2005 Mar-Apr;19(2):109-18.
24. Inhibition of rat liver sulfotransferases SULT1A1 and SULT2A1 and glucuronosyltransferase by dietary flavonoids. Mesia-Vela S and Kauffman FC, Xenobiotica. 2003 Dec;33(12):1211-20.
25. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
26. Estrogen-metabolizing gene polymorphisms in the assessment of female hormone-dependent cancer risk. Mikhailova ON, etal., Pharmacogenomics J. 2006 May-Jun;6(3):189-93.
27. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
28. Association of SULT1A1 phenotype and genotype with prostate cancer risk in African-Americans and Caucasians. Nowell S, etal., Cancer Epidemiol Biomarkers Prev. 2004 Feb;13(2):270-6.
29. Nucleotide sequence of a full-length cDNA (PST-1) for aryl sulfotransferase from rat liver. Ozawa S, etal., Nucleic Acids Res 1990 Jul 11;18(13):4001.
30. The relationship among the polymorphisms of SULT1A1, 1A2 and different types of cancers in Taiwanese. Peng CT, etal., Int J Mol Med. 2003 Jan;11(1):85-9.
31. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
32. SMPDB Annotation Import Pipeline Pipeline to import SMPDB annotations from SMPDB into RGD
33. Estrogen sulfation genes, hormone replacement therapy, and endometrial cancer risk. Rebbeck TR, etal., J Natl Cancer Inst. 2006 Sep 20;98(18):1311-20.
34. GOA pipeline RGD automated data pipeline
35. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
36. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
37. [Association of polymorphisms in SULT1A1 and UGT1A1 Genes with breast cancer risk and phenotypes in Russian women]. Shatalova EG, etal., Mol Biol (Mosk). 2006 Mar-Apr;40(2):263-70.
38. Phase II antioxidant enzyme activities in brain of male and female ACI rats treated chronically with estradiol. Stakhiv TM, etal., Brain Res. 2006 Aug 9;1104(1):80-91. Epub 2006 Jul 5.
39. Phenol sulphotransferase SULT1A1 polymorphism in prostate cancer: lack of association. Steiner M, etal., Arch Toxicol. 2000 Jul;74(4-5):222-5.
40. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
41. Human NAD(P)H:quinone oxidoreductase 1 (NQO1) and sulfotransferase 1A1 (SULT1A1) polymorphisms and urothelial cancer risk in Taiwan. Wang YH, etal., J Cancer Res Clin Oncol. 2008 Feb;134(2):203-9. Epub 2007 Jul 10.
42. A physiogenomic approach to study the regulation of blood pressure. Westhoff TH, etal., Physiol Genomics. 2005 Sep 21;23(1):46-53. Epub 2005 Jun 7.
43. Association of the SULT1A1 R213H polymorphism with colorectal cancer. Wong CF, etal., Clin Exp Pharmacol Physiol. 2002 Sep;29(9):754-8.
44. SULT1A1 polymorphism and esophageal cancer in males. Wu MT, etal., Int J Cancer. 2003 Jan 1;103(1):101-4.
45. Modifying effects of sulfotransferase 1A1 gene polymorphism on the association of breast cancer risk with body mass index or endogenous steroid hormones. Yang G, etal., Breast Cancer Res Treat. 2005 Nov;94(1):63-70.
46. Characterization of a complementary DNA for rat liver aryl sulfotransferase IV and use in evaluating the hepatic gene transcript levels of rats at various stages of 2-acetylaminofluorene-induced hepatocarcinogenesis. Yerokun T, etal., Cancer Res 1992 Sep 1;52(17):4779-86.
47. Sulfotransferase 1A1 (SULT1A1) polymorphism and bladder cancer risk: a case-control study. Zheng L, etal., Cancer Lett. 2003 Dec 8;202(1):61-9.
Additional References at PubMed
PMID:7889867   PMID:7982943   PMID:8033271   PMID:8299966   PMID:8447833   PMID:12390022   PMID:12471039   PMID:16221673   PMID:19548878   PMID:20056724   PMID:21721019   PMID:22041107  
PMID:22081606   PMID:23026138   PMID:23207770   PMID:25370010   PMID:26022216   PMID:31100325  


Genomics

Comparative Map Data
Sult1a1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81190,702,592 - 190,706,112 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1190,702,592 - 190,706,131 (-)EnsemblGRCr8
mRatBN7.21181,272,022 - 181,276,750 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1181,272,023 - 181,275,562 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1189,623,229 - 189,626,764 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01196,809,299 - 196,812,834 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01189,476,705 - 189,480,237 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01198,100,586 - 198,104,106 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1198,100,586 - 198,104,109 (-)Ensemblrn6Rnor6.0
Rnor_5.01205,079,585 - 205,083,105 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41185,829,205 - 185,832,725 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1178,929,499 - 178,933,019 (-)NCBICelera
RGSC_v3.11185,979,085 - 185,982,606 (-)NCBI
Cytogenetic Map1q36NCBI
SULT1A1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381628,605,258 - 28,623,375 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1628,605,008 - 28,612,503 (-)Ensemblhg38GRCh38
GRCh371628,616,579 - 28,634,696 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361628,524,414 - 28,542,367 (-)NCBIBuild 36Build 36hg18NCBI36
Build 341628,524,418 - 28,542,367NCBI
Celera1627,573,787 - 27,591,759 (+)NCBICelera
Cytogenetic Map16p11.2NCBI
HuRef1626,642,169 - 26,659,808 (-)NCBIHuRef
CHM1_11629,629,153 - 29,647,182 (-)NCBICHM1_1
T2T-CHM13v2.01628,772,308 - 28,790,437 (+)NCBIT2T-CHM13v2.0
LOC100969764
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21831,222,978 - 31,241,380 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11634,852,633 - 34,871,037 (+)NCBINHGRI_mPanPan1
SULT1A1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1618,176,156 - 18,179,492 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl618,176,355 - 18,179,489 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha619,755,231 - 19,758,321 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0618,312,221 - 18,315,557 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl618,312,420 - 18,315,554 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1618,111,461 - 18,114,551 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0618,026,685 - 18,029,775 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0618,342,761 - 18,345,851 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
SULT1A1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1526,439,618 - 26,452,997 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_0236660683,122,984 - 3,127,864 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
LOC101697399
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462478213,079,596 - 13,094,149 (-)NCBIHetGla 1.0HetGla 1.0hetGla2

Variants

.
Variants in Sult1a1
20 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:46
Count of miRNA genes:37
Interacting mature miRNAs:43
Transcripts:ENSRNOT00000026186
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1578778Pur4Proteinuria QTL 43.30.003urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)1160111531262090437Rat
1354646Kidm18Kidney mass QTL 185.7kidney mass (VT:0002707)calculated kidney weight (CMO:0000160)1160573753266453731Rat
1354652Kidm20Kidney mass QTL 204.3kidney mass (VT:0002707)calculated kidney weight (CMO:0000160)1186658830266453731Rat
2302378Insul11Insulin level QTL 113.25blood insulin amount (VT:0001560)serum insulin level (CMO:0000358)1153679879198679879Rat
1354653Despr9Despair related QTL 90.00019locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)1177339686222339686Rat
1578770Stresp23Stress response QTL 23kidney sympathetic nerve activity (VT:0004050)stimulated renal sympathetic nerve activity to basal renal sympathetic nerve activity ratio (CMO:0001786)1132760429191848948Rat
2293673Bss27Bone structure and strength QTL 2718.630.0001femur morphology trait (VT:0000559)femur midshaft cortical cross-sectional area (CMO:0001663)1181059071226059071Rat
61326Eae6Experimental allergic encephalomyelitis QTL 65.3body mass (VT:0001259)change in body weight (CMO:0002045)1182383862191260518Rat
2293677Bss41Bone structure and strength QTL 419.380.0001lumbar vertebra size trait (VT:0010518)lumbar vertebra cross-sectional area (CMO:0001689)1181059071226059071Rat
70160Bw18Body weight QTL 185.7body mass (VT:0001259)body weight (CMO:0000012)1153679879205813246Rat
1549830Bss1Bone structure and strength QTL 14.8femur strength trait (VT:0010010)femur ultimate force (CMO:0001675)1182039247227039247Rat
70163Bw20Body weight QTL 205.1body mass (VT:0001259)body weight (CMO:0000012)1183564652228564652Rat
8694166Bw147Body weight QTL 1476.830.001body mass (VT:0001259)body weight gain (CMO:0000420)1153788989198788989Rat
1354624Cm35Cardiac mass QTL355.7heart left ventricle mass (VT:0007031)calculated heart weight (CMO:0000073)1186658830266453731Rat
1600397Edcs4Endometrial carcinoma susceptibility QTL 42.2uterus morphology trait (VT:0001120)percentage of study population developing endometrioid carcinoma during a period of time (CMO:0001759)1176288899270518180Rat
1354636Lmblg1Limb length QTL 16.4tibia length (VT:0004357)tibia length (CMO:0000450)1160573753210707719Rat
1549837Hcar15Hepatocarcinoma resistance QTL 150.05liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)1162548015270518180Rat
2293689Bss47Bone structure and strength QTL 477.250.0001lumbar vertebra size trait (VT:0010518)lumbar vertebra trabecular cross-sectional area (CMO:0001692)1181059071226059071Rat
152025235Bw194Body weight QTL 1944.86body mass (VT:0001259)1132966869252856240Rat
1598853Memor3Memory QTL 34.5exploratory behavior trait (VT:0010471)total horizontal distance resulting from voluntary locomotion in an experimental apparatus (CMO:0001443)1152919152268496042Rat
61341Bp26Blood pressure QTL 26arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1139442053223964440Rat
1354634Kidm12Kidney mass QTL 123.9kidney mass (VT:0002707)right kidney wet weight (CMO:0000082)1160573753210707719Rat
4889428Stresp24Stress response QTL 240.05heart pumping trait (VT:2000009)absolute change in electrocardiographic low frequency R-R spectral component to high frequency R-R spectral component ratio (CMO:0002162)1165278545210278545Rat
2293693Bss22Bone structure and strength QTL 2233.520.0001femur morphology trait (VT:0000559)femur cross-sectional area (CMO:0001661)1181059071226059071Rat
1578759Uae30Urinary albumin excretion QTL 303.30.003urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)1160111531262090437Rat
61343Bp28Blood pressure QTL 28arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1161077990206077990Rat
152025232Bw192Body weight QTL 1923.93body mass (VT:0001259)1127329268206393015Rat
2300161Bmd43Bone mineral density QTL 438.40.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)1181059071226059071Rat
1358902Bw47Body weight QTL 471.67body mass (VT:0001259)body weight (CMO:0000012)199645382221502378Rat
61347Bp197Blood pressure QTL 1974.2arterial blood pressure trait (VT:2000000)blood pressure measurement (CMO:0000003)1168063662213063662Rat
61348Bp30Blood pressure QTL 302.4arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1159894717207261263Rat
2303622Vencon6Ventilatory control QTL 60.001respiration trait (VT:0001943)respiration rate (CMO:0000289)1163992710208992710Rat
8655649Arrd1Age-related retinal degeneration QTL 14.89retinal layer morphology trait (VT:0003727)percentage of study population developing retinopathy during a period of time (CMO:0002453)1109493780193400781Rat
631214Bw61Body weight QTL613.40.0001intramuscular adipose amount (VT:0010044)intramuscular fat area (CMO:0001162)1182535316227535316Rat
7771612Cm80Cardiac mass QTL 808.4heart left ventricle mass (VT:0007031)heart left ventricle weight (CMO:0000776)1146080545243492863Rat
731168Bp154Blood pressure QTL 1543.4arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1103779152223964440Rat
631205Bp196Blood pressure QTL 19640.0001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)198879955208479939Rat
2300174Bmd42Bone mineral density QTL 428.40.0001lumbar vertebra mineral mass (VT:0010511)bone mineral density (CMO:0001226)1181059071226059071Rat
1300158Bp173Blood pressure QTL 1733.48arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)1155359438194575574Rat
737828Hcas3Hepatocarcinoma susceptibility QTL 34.9liver integrity trait (VT:0010547)liver tumorous lesion volume to total liver volume ratio (CMO:0001082)1153679879232414077Rat
1354661Bw33Body weight QTL 335.2body mass (VT:0001259)body weight (CMO:0000012)1160573753266453731Rat
1358886Bp260Blood pressure QTL 2603.67arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1160574007235238518Rat
1331751Bp199Blood pressure QTL 1993.60022arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)1116099376191260518Rat
2293654Bss30Bone structure and strength QTL 3032.650.0001femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)1181059071226059071Rat
724531Uae5Urinary albumin excretion QTL 54urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)1160111426262090599Rat
2300187Bmd41Bone mineral density QTL 418.90.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)1181059071226059071Rat
1641895Bp298Blood pressure QTL 298arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1132760429191848948Rat
70209Niddm23Non-insulin dependent diabetes mellitus QTL 232.82blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)1162753891207753891Rat
1354580Scort1Serum corticosterone level QTL 13.4blood corticosterone amount (VT:0005345)blood corticosterone level (CMO:0001172)1154961463266453731Rat
1358294Bw37Body weight QTL 3750.000011body mass (VT:0001259)body weight (CMO:0000012)1180739993225739993Rat
634314Niddm44Non-insulin dependent diabetes mellitus QTL 44blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)151941022208479811Rat
2312420Pur17Proteinuria QTL 177.10.0001urine protein amount (VT:0005160)urine total protein excretion rate (CMO:0000756)1172718770228180370Rat
10059600Bp378Blood pressure QTL 3783.080.05arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1186298393231298393Rat
1354591Cm36Cardiac mass QTL 364.1heart left ventricle mass (VT:0007031)calculated heart weight (CMO:0000073)1111949780210707719Rat
2312558Glom17Glomerulus QTL 173.90.001kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)1175967553200707874Rat
10059597Bp377Blood pressure QTL 3773.420.025arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)134565911208798288Rat
631519Pia11Pristane induced arthritis QTL 115.3joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)193903998191260518Rat
619614Bp78Blood pressure QTL 780.001arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)1178547286206690557Rat
634321Hc1Hypercalciuria QTL 12.91urine calcium amount (VT:0002985)urine calcium excretion rate (CMO:0000763)1188241285250779312Rat
724562Rends1Renal damage susceptibility QTL 10.05kidney glomerulus integrity trait (VT:0010546)index of glomerular damage (CMO:0001135)1139442053223964440Rat
2292222Bp307Blood pressure QTL 3073.060.0014arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1186298393231298393Rat
2292220Bp306Blood pressure QTL 3063.470.00087arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1186298393231298393Rat
1354615Cm32Cardiac mass QTL 325.2heart left ventricle mass (VT:0007031)heart left ventricle wet weight (CMO:0000071)1111949780210707719Rat
1600380Niddm70Non-insulin dependent diabetes mellitus QTL 703.10.0008blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)1185979875230979875Rat
1354610Bw34Body weight QTL 344.1body mass (VT:0001259)body weight (CMO:0000012)1160573753266453731Rat
1354620Kidm19Kidney mass QTL 194kidney mass (VT:0002707)calculated kidney weight (CMO:0000160)1160573753210707719Rat
1576310Schws2Schwannoma susceptibility QTL 20.029nervous system integrity trait (VT:0010566)percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)1153788989198788989Rat
1354618Kidm15Kidney mass QTL 155kidney mass (VT:0002707)left kidney wet weight (CMO:0000083)1165707719210707719Rat
6903303Scl34Serum cholesterol QTL 342.50.0033blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)1173363824227535316Rat
631544Bp84Blood pressure QTL 845.6arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1132760429191190115Rat
152025212Bw190Body weight QTL 1905.7body mass (VT:0001259)1132966869206393015Rat
1358189Cstrr1Cold stress response QTL 10.0001catecholamine amount (VT:0010543)urine norepinephrine level (CMO:0001629)1132760429191848948Rat
1354606Bp246Blood pressure QTL 2463.6arterial blood pressure trait (VT:2000000)pulse pressure (CMO:0000292)1111949780228180370Rat
738032Hcas5Hepatocarcinoma susceptibility QTL 53.12liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)1185857683270518180Rat
2325727Pia41Pristane induced arthritis QTL 41joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1188241285233241285Rat
2325725Eae31Experimental allergic encephalomyelitis QTL 31nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis severity score (CMO:0001419)1188241285197807511Rat
1354602Bw35Body weight QTL 3512.2body mass (VT:0001259)body weight (CMO:0000012)1160573753210707719Rat
7411599Foco11Food consumption QTL 1118.50.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)1153788989198788989Rat
631670Iddm10Insulin dependent diabetes mellitus QTL 101.9blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)1183564652205813246Rat

Markers in Region
RH127510  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21181,272,105 - 181,272,289 (+)MAPPERmRatBN7.2
Rnor_6.01198,100,669 - 198,100,852NCBIRnor6.0
Rnor_5.01205,079,668 - 205,079,851UniSTSRnor5.0
RGSC_v3.41185,829,288 - 185,829,471UniSTSRGSC3.4
Celera1178,929,582 - 178,929,765UniSTS
Cytogenetic Map1q35-q37UniSTS
Cytogenetic Map1q36UniSTS
AI266890  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21181,272,146 - 181,272,258 (+)MAPPERmRatBN7.2
Rnor_6.01198,100,710 - 198,100,821NCBIRnor6.0
Rnor_5.01205,079,709 - 205,079,820UniSTSRnor5.0
RGSC_v3.41185,829,329 - 185,829,440UniSTSRGSC3.4
Celera1178,929,623 - 178,929,734UniSTS
Cytogenetic Map1q35-q37UniSTS
Cytogenetic Map1q36UniSTS
D1Bda35  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr81190,702,829 - 190,703,214 (+)Marker Load Pipeline
mRatBN7.21181,272,260 - 181,272,645 (+)MAPPERmRatBN7.2
Rnor_6.01198,100,824 - 198,101,208NCBIRnor6.0
Rnor_5.01205,079,823 - 205,080,207UniSTSRnor5.0
RGSC_v3.41185,829,443 - 185,829,827UniSTSRGSC3.4
Celera1178,929,737 - 178,930,121UniSTS
Cytogenetic Map1q35-q37UniSTS
BE120712  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21181,276,538 - 181,276,718 (+)MAPPERmRatBN7.2
Rnor_6.01198,105,102 - 198,105,281NCBIRnor6.0
Rnor_5.01205,084,101 - 205,084,280UniSTSRnor5.0
RGSC_v3.41185,833,721 - 185,833,900UniSTSRGSC3.4
Celera1178,934,015 - 178,934,194UniSTS
Cytogenetic Map1q35-q37UniSTS


Related Rat Strains
The following Strains have been annotated to Sult1a1
SD-Del(Sult1a1-Spn)/YahIcsOrl     SD-Dp(Sult1a1-Spn)/YahIcsOrl    


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 161 91 90 59 89 59 6 353 189 11 140 81 91 31 17 17

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_031834 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AF394783 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC072468 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH473956 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ209630 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ210886 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ214244 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ218459 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ218506 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ218658 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ219174 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ219178 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ219521 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ219542 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ219948 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000001 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  L16241 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  L19998 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X52883 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X68640 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000026186   ⟹   ENSRNOP00000026186
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1190,702,592 - 190,706,131 (-)Ensembl
mRatBN7.2 Ensembl1181,272,023 - 181,275,562 (-)Ensembl
Rnor_6.0 Ensembl1198,100,586 - 198,104,109 (-)Ensembl
RefSeq Acc Id: NM_031834   ⟹   NP_114022
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81190,702,592 - 190,706,112 (-)NCBI
mRatBN7.21181,272,023 - 181,275,543 (-)NCBI
Rnor_6.01198,100,586 - 198,104,106 (-)NCBI
Rnor_5.01205,079,585 - 205,083,105 (-)NCBI
RGSC_v3.41185,829,205 - 185,832,725 (-)RGD
Celera1178,929,499 - 178,933,019 (-)RGD
Sequence:
RefSeq Acc Id: NP_114022   ⟸   NM_031834
- UniProtKB: Q548D2 (UniProtKB/Swiss-Prot),   P17988 (UniProtKB/Swiss-Prot),   A6I9A6 (UniProtKB/TrEMBL),   A6I9A5 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000026186   ⟸   ENSRNOT00000026186
Protein Domains
Sulfotransferase

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P17988-F1-model_v2 AlphaFold P17988 1-291 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13690405
Promoter ID:EPDNEW_R930
Type:multiple initiation site
Name:Sult1a1_1
Description:sulfotransferase family 1A member 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01198,104,118 - 198,104,178EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:3767 AgrOrtholog
BioCyc Gene G2FUF-57433 BioCyc
Ensembl Genes ENSRNOG00000019342 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000026186 ENTREZGENE
  ENSRNOT00000026186.5 UniProtKB/Swiss-Prot
Gene3D-CATH 3.40.50.300 UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:7098229 IMAGE-MGC_LOAD
InterPro P-loop_NTPase UniProtKB/Swiss-Prot
  Sulfotransferase_dom UniProtKB/Swiss-Prot
KEGG Report rno:83783 UniProtKB/Swiss-Prot
MGC_CLONE MGC:91614 IMAGE-MGC_LOAD
NCBI Gene Sult1a1 ENTREZGENE
PANTHER SULFOTRANSFERASE SULT UniProtKB/Swiss-Prot
Pfam Sulfotransfer_1 UniProtKB/Swiss-Prot
PharmGKB SULT1A1 RGD
PhenoGen Sult1a1 PhenoGen
RatGTEx ENSRNOG00000019342 RatGTEx
Superfamily-SCOP SSF52540 UniProtKB/Swiss-Prot
UniProt A6I9A5 ENTREZGENE, UniProtKB/TrEMBL
  A6I9A6 ENTREZGENE, UniProtKB/TrEMBL
  A6I9A7_RAT UniProtKB/TrEMBL
  P17988 ENTREZGENE
  Q548D2 ENTREZGENE
  ST1A1_RAT UniProtKB/Swiss-Prot
UniProt Secondary Q548D2 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-11-12 Sult1a1  sulfotransferase family 1A member 1  Sult1a1  sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-10-23 Sult1a1  sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1  Sult1a1  sulfotransferase family 1A, phenol-preferring, member 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2003-04-09 Sult1a1  sulfotransferase family 1A, phenol-preferring, member 1      Symbol and Name updated 629477 APPROVED
2003-03-12 Sult1a1  sulfotransferase family 1A, phenol-preferring, member 1  Sult1a3    Data merged from RGD:621051 628472 PROVISIONAL
2002-08-07 Sult1a3        Symbol and Name status set to provisional 70820 PROVISIONAL
2001-06-26 Sult1a1  sulphotransferase family, cytosolic, 1A, phenol-prefering, member 1      Symbol and Name updated to reflect Human and Mouse nomenclature 67952 APPROVED
2001-06-26 St1a1  Phenol sulfotransferase 1a1      Symbol and Name withdrawn 67952 WITHDRAWN

RGD Curation Notes
Note Type Note Reference
gene_disease downregulated at transcriptional and translational level during hepatocarcinogenesis induced by 2-acetylaminofluorine (2AAF) 730163
gene_expression expressed in liver 730083
gene_expression expressed in liver 730163
gene_protein 291 amino acid protein 730163