Rbp2 (retinol binding protein 2) - Rat Genome Database

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Gene: Rbp2 (retinol binding protein 2) Rattus norvegicus
Analyze
Symbol: Rbp2
Name: retinol binding protein 2
RGD ID: 3544
Description: Enables retinol binding activity. Predicted to be involved in fatty acid transport and retinoid metabolic process. Predicted to be active in cytosol and nucleus. Orthologous to human RBP2 (retinol binding protein 2); PARTICIPATES IN retinol metabolic pathway; INTERACTS WITH 17alpha-ethynylestradiol; 17beta-estradiol; 2,2',4,4'-Tetrabromodiphenyl ether.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: cellular retinol-binding protein II; CRBP-II; retinol binding protein 2, cellular; retinol-binding protein 2; Retinol-binding protein 2 cellular; Retinol-binding protein 2, cellular
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr88107,958,670 - 107,983,850 (+)NCBIGRCr8
mRatBN7.2899,079,293 - 99,104,489 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl899,079,104 - 99,104,473 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx8104,752,605 - 104,772,947 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.08102,951,869 - 102,972,216 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.08100,794,370 - 100,814,714 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.08106,479,253 - 106,527,726 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl8106,503,504 - 106,527,711 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.08105,945,338 - 105,969,565 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.48103,665,461 - 103,685,771 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.18103,684,970 - 103,705,027 (+)NCBI
Celera898,493,627 - 98,513,957 (+)NCBICelera
RH 3.4 Map81052.2RGD
Cytogenetic Map8q31NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


1 to 20 of 61 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Rbp2Rat1,2-dimethylhydrazine decreases expressionISORbp2 (Mus musculus)64804641 and 2-Dimethylhydrazine results in decreased expression of RBP2 mRNACTDPMID:22206623
Rbp2Rat17alpha-ethynylestradiol multiple interactionsISORbp2 (Mus musculus)6480464[Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of RBP2 mRNACTDPMID:17942748
Rbp2Rat17alpha-ethynylestradiol decreases expressionISORBP2 (Homo sapiens)6480464Ethinyl Estradiol results in decreased expression of RBP2 mRNACTDPMID:18936297
Rbp2Rat17alpha-ethynylestradiol increases expressionEXP 6480464Ethinyl Estradiol results in increased expression of RBP2 mRNACTDPMID:17557909
Rbp2Rat17beta-estradiol multiple interactionsEXP 6480464[Estradiol co-treated with Plant Preparations] results in increased expression of RBP2 mRNACTDPMID:26945725
Rbp2Rat17beta-estradiol decreases expressionEXP 6480464Estradiol results in decreased expression of RBP2 mRNA and Estradiol results in decreased expression of RBP2 proteinCTDPMID:32145629
Rbp2Rat17beta-estradiol increases expressionEXP 6480464Estradiol results in increased expression of RBP2 mRNACTDPMID:26945725
Rbp2Rat2,2',4,4'-Tetrabromodiphenyl ether affects expressionISORbp2 (Mus musculus)64804642 more ...CTDPMID:30294300
Rbp2Rat2,2',4,4'-Tetrabromodiphenyl ether increases expressionEXP 64804642 more ...CTDPMID:31826744
Rbp2Rat2,3,7,8-tetrachlorodibenzodioxine multiple interactionsISORbp2 (Mus musculus)6480464[Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of RBP2 mRNACTDPMID:17942748
Rbp2Rat2,3,7,8-tetrachlorodibenzodioxine increases expressionEXP 6480464Tetrachlorodibenzodioxin results in increased expression of RBP2 mRNACTDPMID:33387578
Rbp2Rat2,3,7,8-tetrachlorodibenzodioxine affects expressionISORbp2 (Mus musculus)6480464Tetrachlorodibenzodioxin affects the expression of RBP2 mRNACTDPMID:21570461
Rbp2Rat2-hydroxypropanoic acid increases expressionISORBP2 (Homo sapiens)6480464Lactic Acid results in increased expression of RBP2 mRNACTDPMID:30851411
Rbp2Rat6-propyl-2-thiouracil multiple interactionsISORbp2 (Mus musculus)6480464[Propylthiouracil co-treated with Iodine deficiency] results in decreased expression of RBP2 mRNACTDPMID:36706583
Rbp2Rat9-cis-retinoic acid increases expressionEXP 6480464Alitretinoin results in increased expression of RBP2 mRNACTDPMID:19409899
Rbp2Ratacetamide increases expressionEXP 6480464acetamide results in increased expression of RBP2 mRNACTDPMID:31881176
Rbp2Ratall-trans-retinoic acid increases expressionISORBP2 (Homo sapiens)6480464Tretinoin results in increased expression of RBP2 mRNACTDPMID:17023940
Rbp2Ratall-trans-retinoic acid affects expressionISORBP2 (Homo sapiens)6480464Tretinoin affects the expression of RBP2 mRNACTDPMID:31600526
Rbp2Ratall-trans-retinoic acid increases expressionEXP 6480464Tretinoin results in increased expression of RBP2 mRNACTDPMID:19409899
Rbp2Ratall-trans-retinol multiple interactionsISORbp2 (Mus musculus)6480464[RBP1 gene mutant form results in increased abundance of Vitamin A] which results in increased expression of RBP2 mRNACTDPMID:21670153

1 to 20 of 61 rows

Biological Process

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Rbp2Ratfatty acid transport involved_inIBAMGI:88038 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Rbp2Ratretinoid metabolic process involved_inISORbp2 (Mus musculus)1624291MGI:2672086 PMID:12138113 and PMID:35552670RGDPMID:12138113 and PMID:35552670
Rbp2Ratretinol metabolic process  TAS 729693 RGD 
Rbp2Rattriglyceride biosynthetic process acts_upstream_of_or_withinISORbp2 (Mus musculus)1624291 PMID:14966132RGDPMID:14966132

Cellular Component

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Rbp2Ratcytoplasm located_inIEAUniProtKB-KW:KW-09631600115GO_REF:0000043UniProtGO_REF:0000043
Rbp2Ratcytoplasm located_inIEAUniProtKB-SubCell:SL-00861600115GO_REF:0000044UniProtGO_REF:0000044
Rbp2Ratcytosol is_active_inIBAMGI:101790 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Rbp2Ratcytosol is_active_inISORbp2 (Mus musculus)1624291 PMID:25992653RGDPMID:25992653
Rbp2Ratnucleus is_active_inIBAMGI:101790 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033

Molecular Function
1 to 10 of 10 rows

  
1 to 10 of 10 rows

RGD Manual Annotations


  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Rbp2Ratretinol metabolic pathway   ISORBP2 (Homo sapiens)6484679 RGD 

1 to 16 of 16 rows
#
Reference Title
Reference Citation
1. The cellular retinol binding protein II gene. Sequence analysis of the rat gene, chromosomal localization in mice and humans, and documentation of its close linkage to the cellular retinol binding protein gene. Demmer LA, etal., J Biol Chem 1987 Feb 25;262(6):2458-67.
2. New insights on the protein-ligand interaction differences between the two primary cellular retinol carriers. Franzoni L, etal., J Lipid Res. 2010 Jun;51(6):1332-43. Epub 2009 Nov 25.
3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
4. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
5. Differential expression of interphotoreceptor retinoid-binding protein, opsin, cellular retinaldehyde-binding protein, and basic fibroblastic growth factor. Gonzalez-Fernandez F, etal., Exp Eye Res 1993 Apr;56(4):411-27.
6. Mechanisms involved in the intestinal absorption of dietary vitamin A and provitamin A carotenoids. Harrison EH Biochim Biophys Acta. 2012 Jan;1821(1):70-7. Epub 2011 Jun 12.
7. Genetic isolation of a region of chromosome 8 that exerts major effects on blood pressure and cardiac mass in the spontaneously hypertensive rat. Kren V, etal., J Clin Invest 1997 Feb 15;99(4):577-81
8. High-density rat radiation hybrid maps containing over 24,000 SSLPs, genes, and ESTs provide a direct link to the rat genome sequence. Kwitek AE, etal., Genome Res. 2004 Apr;14(4):750-7
9. Rat cellular retinol-binding protein II: use of a cloned cDNA to define its primary structure, tissue-specific expression, and developmental regulation. Li E, etal., Proc Natl Acad Sci U S A 1986 Aug;83(16):5779-83.
10. Two homologous rat cellular retinol-binding proteins differ in local conformational flexibility. Lu J, etal., J Mol Biol. 2003 Jul 18;330(4):799-812.
11. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
12. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
13. GOA pipeline RGD automated data pipeline
14. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
15. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
16. Gene-based anchoring of the rat genetic linkage and cytogenetic maps: new regional localizations, orientation of the linkage groups, and insights into mammalian chromosome evolution. Szpirer C, etal., Mamm Genome 1998 Sep;9(9):721-34
1 to 16 of 16 rows
PMID:2645288   PMID:8487303   PMID:8889548   PMID:10047490   PMID:17692466   PMID:25585692   PMID:27142737  



Rbp2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr88107,958,670 - 107,983,850 (+)NCBIGRCr8
mRatBN7.2899,079,293 - 99,104,489 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl899,079,104 - 99,104,473 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx8104,752,605 - 104,772,947 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.08102,951,869 - 102,972,216 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.08100,794,370 - 100,814,714 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.08106,479,253 - 106,527,726 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl8106,503,504 - 106,527,711 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.08105,945,338 - 105,969,565 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.48103,665,461 - 103,685,771 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.18103,684,970 - 103,705,027 (+)NCBI
Celera898,493,627 - 98,513,957 (+)NCBICelera
RH 3.4 Map81052.2RGD
Cytogenetic Map8q31NCBI
RBP2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh383139,452,884 - 139,476,516 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl3139,452,884 - 139,480,747 (-)EnsemblGRCh38hg38GRCh38
GRCh373139,171,726 - 139,195,358 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 363140,654,416 - 140,678,042 (-)NCBINCBI36Build 36hg18NCBI36
Build 343140,654,424 - 140,678,050NCBI
Celera3137,594,686 - 137,618,327 (-)NCBICelera
Cytogenetic Map3q23NCBI
HuRef3136,547,188 - 136,570,833 (-)NCBIHuRef
CHM1_13139,135,301 - 139,158,940 (-)NCBICHM1_1
T2T-CHM13v2.03142,200,416 - 142,224,059 (-)NCBIT2T-CHM13v2.0
Rbp2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39998,372,590 - 98,391,824 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl998,368,168 - 98,391,834 (+)EnsemblGRCm39 Ensembl
GRCm38998,490,537 - 98,509,771 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl998,486,115 - 98,509,781 (+)EnsemblGRCm38mm10GRCm38
MGSCv37998,390,956 - 98,410,190 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36998,299,905 - 98,319,089 (+)NCBIMGSCv36mm8
Celera998,036,063 - 98,055,300 (+)NCBICelera
Cytogenetic Map9E3.3NCBI
cM Map951.37NCBI
Rbp2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555086,111,168 - 6,136,010 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049555086,111,558 - 6,135,929 (+)NCBIChiLan1.0ChiLan1.0
RBP2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22137,366,814 - 137,394,504 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan13137,369,656 - 137,399,234 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v03136,488,536 - 136,513,337 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.13144,089,322 - 144,112,840 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl3144,089,322 - 144,112,840 (-)Ensemblpanpan1.1panPan2
RBP2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12335,619,215 - 35,642,249 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2335,619,221 - 35,642,213 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2335,607,084 - 35,630,082 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02336,157,741 - 36,180,747 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2336,157,751 - 36,180,723 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12335,838,270 - 35,861,272 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02335,911,556 - 35,934,581 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02336,153,873 - 36,176,911 (-)NCBIUU_Cfam_GSD_1.0
Rbp2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560274,807,601 - 74,831,624 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365401,547,386 - 1,571,430 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365401,547,406 - 1,571,374 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
RBP2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1380,320,931 - 80,352,975 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11380,321,024 - 80,346,032 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21387,988,050 - 88,013,085 (-)NCBISscrofa10.2Sscrofa10.2susScr3
RBP2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11551,077,753 - 51,102,110 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1551,078,169 - 51,102,249 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604124,055,079 - 24,079,140 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Rbp2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473016,016,524 - 16,060,141 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473016,018,142 - 16,060,179 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

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Variants in Rbp2
122 total Variants

Predicted Target Of
Summary Value
Count of predictions:45
Count of miRNA genes:40
Interacting mature miRNAs:45
Transcripts:ENSRNOT00000018755
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


1 to 10 of 35 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
1300177Cm2Cardiac mass QTL 23.65heart mass (VT:0007028)heart weight (CMO:0000017)854259986100382532Rat
1549909Stresp11Stress response QTL 116.830.0019stress-related behavior trait (VT:0010451)number of approaches toward negative stimulus before onset of defensive burying response (CMO:0001960)873473045118473045Rat
1554321Bmd3Bone mineral density QTL 37.90.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)840952565123900184Rat
9590292Uminl3Urine mineral level QTL 33.620.001urine mineral amount (VT:0015086)urine electrolyte level (CMO:0000593)871888757116888757Rat
1578769Uae31Urinary albumin excretion QTL 313.30.001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)830848154101699754Rat
738011Anxrr9Anxiety related response QTL 96.1exploratory behavior trait (VT:0010471)number of entries into a discrete space in an experimental apparatus (CMO:0000960)893535351123900184Rat
8693654Alc32Alcohol consumption QTL 3220.755drinking behavior trait (VT:0001422)calculated ethanol drink intake rate (CMO:0001615)888612425107550209Rat
1358912Bw51Body weight QTL 512.95body mass (VT:0001259)body weight (CMO:0000012)851351728107062046Rat
1578765Klgr1Kidney lesion grade QTL 13.30.0001kidney morphology trait (VT:0002135)organ lesion measurement (CMO:0000677)830848154101699754Rat
738014Anxrr15Anxiety related response QTL 153.60.005locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)895718998123900184Rat

1 to 10 of 35 rows
D8Mgh3  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr88107,982,728 - 107,982,864 (+)Marker Load Pipeline
mRatBN7.2899,103,367 - 99,103,503 (+)MAPPERmRatBN7.2
Rnor_6.08106,526,605 - 106,526,740NCBIRnor6.0
Rnor_5.08105,968,444 - 105,968,579UniSTSRnor5.0
RGSC_v3.48103,684,650 - 103,684,785UniSTSRGSC3.4
RGSC_v3.48103,684,649 - 103,684,785RGDRGSC3.4
RGSC_v3.18103,704,104 - 103,704,240RGD
Celera898,512,833 - 98,512,971UniSTS
RH 3.4 Map81051.79RGD
RH 3.4 Map81051.79UniSTS
RH 2.0 Map8841.5RGD
SHRSP x BN Map859.54RGD
FHH x ACI Map869.0899RGD
Cytogenetic Map8q31UniSTS
D8Wox6  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr88107,962,975 - 107,963,099 (+)Marker Load Pipeline
mRatBN7.2899,083,612 - 99,083,736 (+)MAPPERmRatBN7.2
Rnor_6.08106,506,850 - 106,506,973NCBIRnor6.0
Rnor_5.08105,948,689 - 105,948,812UniSTSRnor5.0
RGSC_v3.48103,664,894 - 103,665,018RGDRGSC3.4
RGSC_v3.48103,664,895 - 103,665,018UniSTSRGSC3.4
RGSC_v3.18103,684,349 - 103,684,473RGD
Celera898,493,061 - 98,493,184UniSTS
RH 3.4 Map81052.4RGD
RH 3.4 Map81052.4UniSTS
RH 2.0 Map8834.8RGD
Cytogenetic Map8q31UniSTS
D8Arb17  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr88107,962,659 - 107,963,151 (+)Marker Load Pipeline
mRatBN7.2899,083,296 - 99,083,788 (+)MAPPERmRatBN7.2
Rnor_6.08106,506,534 - 106,507,025NCBIRnor6.0
Rnor_5.08105,948,373 - 105,948,864UniSTSRnor5.0
RGSC_v3.48103,664,579 - 103,665,070UniSTSRGSC3.4
Celera898,492,745 - 98,493,236UniSTS
RH 3.4 Map81052.0UniSTS
RH 3.4 Map81052.0RGD
RH 2.0 Map8852.6RGD
SHRSP x BN Map860.6299RGD
Cytogenetic Map8q31UniSTS
D8Mgh15  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr88107,970,397 - 107,970,527 (+)Marker Load Pipeline
Rnor_5.08105,956,109 - 105,956,241NCBIRnor5.0
RGSC_v3.48103,672,316 - 103,672,447RGDRGSC3.4
RGSC_v3.18103,691,771 - 103,691,902RGD
Cytogenetic Map8q31UniSTS
RH94395  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr88107,962,959 - 107,963,126 (+)Marker Load Pipeline
mRatBN7.2899,083,596 - 99,083,763 (+)MAPPERmRatBN7.2
Rnor_6.08106,506,834 - 106,507,000NCBIRnor6.0
Rnor_5.08105,948,673 - 105,948,839UniSTSRnor5.0
RGSC_v3.48103,664,879 - 103,665,045UniSTSRGSC3.4
Celera898,493,045 - 98,493,211UniSTS
RH 3.4 Map81052.2UniSTS
Cytogenetic Map8q31UniSTS




alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 3 30 88 79 87 57 16 57 6 166 54 77 45 58 30



Ensembl Acc Id: ENSRNOT00000018755   ⟹   ENSRNOP00000018755
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl899,079,104 - 99,104,473 (+)Ensembl
Rnor_6.0 Ensembl8106,503,504 - 106,527,711 (+)Ensembl
RefSeq Acc Id: NM_012640   ⟹   NP_036772
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr88107,963,542 - 107,983,850 (+)NCBI
mRatBN7.2899,084,179 - 99,104,489 (+)NCBI
Rnor_6.08106,507,416 - 106,527,726 (+)NCBI
Rnor_5.08105,945,338 - 105,969,565 (+)NCBI
RGSC_v3.48103,665,461 - 103,685,771 (+)RGD
Celera898,493,627 - 98,513,957 (+)RGD
Sequence:
RefSeq Acc Id: XM_006243607   ⟹   XP_006243669
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr88107,958,670 - 107,983,834 (+)NCBI
mRatBN7.2899,079,293 - 99,104,489 (+)NCBI
Rnor_6.08106,503,499 - 106,527,711 (+)NCBI
Rnor_5.08105,945,338 - 105,969,565 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039080832   ⟹   XP_038936760
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr88107,958,670 - 107,983,834 (+)NCBI
mRatBN7.2899,079,293 - 99,104,489 (+)NCBI
1 to 9 of 9 rows
Protein RefSeqs NP_036772 (Get FASTA)   NCBI Sequence Viewer  
  XP_006243669 (Get FASTA)   NCBI Sequence Viewer  
  XP_038936760 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAA40963 (Get FASTA)   NCBI Sequence Viewer  
  AAA42022 (Get FASTA)   NCBI Sequence Viewer  
  EDL77463 (Get FASTA)   NCBI Sequence Viewer  
  EDL77464 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000018755.5
GenBank Protein P06768 (Get FASTA)   NCBI Sequence Viewer  
1 to 9 of 9 rows
RefSeq Acc Id: NP_036772   ⟸   NM_012640
- UniProtKB: P06768 (UniProtKB/Swiss-Prot),   A6I2B3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006243669   ⟸   XM_006243607
- Peptide Label: isoform X1
- UniProtKB: P06768 (UniProtKB/Swiss-Prot),   A6I2B3 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000018755   ⟸   ENSRNOT00000018755
RefSeq Acc Id: XP_038936760   ⟸   XM_039080832
- Peptide Label: isoform X1
- UniProtKB: P06768 (UniProtKB/Swiss-Prot),   A6I2B3 (UniProtKB/TrEMBL)
Name Modeler Protein Id AA Range Protein Structure
AF-P06768-F1-model_v2 AlphaFold P06768 1-134 view protein structure


eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

RGD ID:13696203
Promoter ID:EPDNEW_R6727
Type:single initiation site
Name:Rbp2_1
Description:retinol binding protein 2
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.08106,503,475 - 106,503,535EPDNEW


1 to 28 of 28 rows
Database
Acc Id
Source(s)
BioCyc Gene G2FUF-29418 BioCyc
BioCyc Pathway PWY-6857 [retinol biosynthesis] BioCyc
  PWY-6861 [the visual cycle I (vertebrates)] BioCyc
  PWY-6872 [retinoate biosynthesis I] BioCyc
  PWY-6875 [retinoate biosynthesis II] BioCyc
BioCyc Pathway Image PWY-6857 BioCyc
  PWY-6861 BioCyc
  PWY-6872 BioCyc
  PWY-6875 BioCyc
Ensembl Genes ENSRNOG00000013932 Ensembl, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000018755.7 UniProtKB/Swiss-Prot
Gene3D-CATH 2.40.128.20 UniProtKB/Swiss-Prot
InterPro Calycin UniProtKB/Swiss-Prot
  Fatty_acid-bd UniProtKB/Swiss-Prot
  ILBP UniProtKB/Swiss-Prot
  Lipocln_cytosolic_FA-bd_dom UniProtKB/Swiss-Prot
KEGG Report rno:24710 UniProtKB/Swiss-Prot
NCBI Gene 24710 ENTREZGENE
PANTHER PTHR11955 UniProtKB/Swiss-Prot
Pfam Lipocalin UniProtKB/Swiss-Prot
PhenoGen Rbp2 PhenoGen
PRINTS FATTYACIDBP UniProtKB/Swiss-Prot
PROSITE FABP UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000013932 RatGTEx
Superfamily-SCOP SSF50814 UniProtKB/Swiss-Prot
UniProt A6I2B3 ENTREZGENE, UniProtKB/TrEMBL
  A6I2B4_RAT UniProtKB/TrEMBL
  P06768 ENTREZGENE, UniProtKB/Swiss-Prot
1 to 28 of 28 rows


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-12-09 Rbp2  retinol binding protein 2  Rbp2  retinol binding protein 2, cellular  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2004-09-10 Rbp2  retinol binding protein 2, cellular    retinol-binding protein 2   Name updated 1299863 APPROVED
2002-06-10 Rbp2  retinol-binding protein 2       Name updated 70585 PROVISIONAL

Note Type Note Reference
gene_expression found primarily in the enterocytes of small intestine 61054
gene_expression found primarily in the enterocytes of small intestine 61489
gene_homology highly conserved in rats, mice, and humans 61054
gene_homology highly conserved in rats, mice, and humans 61489
gene_process may play a role in the intestinal absorption and/or metabolism of vitamin A 61054
gene_process may modulate the supply of retinoic acid to the nuclei of endometrial cells during the menstrual cycle 61054
gene_transcript contains 4 exons that span 0.65 kb 61054